Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3tgr_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TRP 2.A NE1 GLU 48.A OE1 no hydrogen 2.686 N/A LEU 9.A N GLN 60.A OE1 no hydrogen 2.880 N/A PHE 10.A N CYS 102.A O no hydrogen 3.141 N/A CYS 11.A SG ALA 30.A O no hydrogen 3.539 N/A ALA 12.A N HIS 100.A O no hydrogen 2.773 N/A SER 13.A N VAL 32.A O no hydrogen 3.090 N/A ALA 15.A N SER 13.A OG no hydrogen 3.387 N/A LYS 16.A N ASN 24.A OD1 no hydrogen 3.208 N/A GLU 19.A N LYS 16.A O no hydrogen 3.209 N/A VAL 22.A N SER 93.A O no hydrogen 3.128 N/A VAL 25.A N GLU 21.A O no hydrogen 2.888 N/A TRP 26.A N VAL 22.A O no hydrogen 2.877 N/A ALA 27.A N HIS 23.A O no hydrogen 3.209 N/A THR 28.A N ASN 24.A O no hydrogen 2.953 N/A THR 28.A OG1 ASN 24.A O no hydrogen 3.069 N/A THR 28.A OG1 VAL 25.A O no hydrogen 3.048 N/A HIS 29.A N TRP 26.A O no hydrogen 3.364 N/A HIS 29.A NE2 GLU 71.A OE1 no hydrogen 2.876 N/A ALA 30.A N ALA 27.A O no hydrogen 3.073 N/A CYS 31.A N ALA 27.A O no hydrogen 2.608 N/A VAL 32.A N CYS 11.A O no hydrogen 3.023 N/A THR 34.A N SER 13.A O no hydrogen 3.294 N/A THR 34.A OG1 ASP 14.A OD1 no hydrogen 2.538 N/A MET 41.A N THR 128.A O no hydrogen 2.860 N/A GLU 48.A N CYS 123.A O no hydrogen 3.224 N/A MET 52.A N GLY 119.A O no hydrogen 2.934 N/A TRP 53.A N ASN 51.A OD1 no hydrogen 3.094 N/A LYS 54.A N ASN 51.A O no hydrogen 3.052 N/A ASN 55.A ND2 TYR 340.A O no hydrogen 3.357 N/A MET 57.A N ASN 55.A OD1 no hydrogen 2.876 N/A VAL 58.A N ASN 55.A O no hydrogen 3.258 N/A GLN 60.A N ASP 56.A O no hydrogen 2.962 N/A GLN 60.A NE2 THR 7.A O no hydrogen 2.535 N/A GLN 60.A NE2 ASP 56.A OD2 no hydrogen 3.216 N/A MET 61.A N MET 57.A O no hydrogen 2.919 N/A HIS 62.A N VAL 58.A O no hydrogen 2.759 N/A GLU 63.A N GLU 59.A O no hydrogen 3.104 N/A ASP 64.A N GLN 60.A O no hydrogen 3.297 N/A ILE 65.A N MET 61.A O no hydrogen 3.052 N/A ILE 66.A N HIS 62.A O no hydrogen 3.041 N/A SER 67.A N GLU 63.A O no hydrogen 2.858 N/A LEU 68.A N ASP 64.A O no hydrogen 2.563 N/A TRP 69.A N ILE 65.A O no hydrogen 2.767 N/A ASP 70.A N ILE 66.A O no hydrogen 2.953 N/A ASP 70.A N SER 67.A O no hydrogen 2.924 N/A GLU 71.A N SER 67.A O no hydrogen 3.245 N/A SER 72.A N LEU 68.A O no hydrogen 3.152 N/A SER 72.A OG LEU 68.A O no hydrogen 2.702 N/A LYS 74.A N SER 72.A O no hydrogen 3.251 N/A VAL 77.A N ILE 290.A O no hydrogen 3.195 N/A LYS 78.A N ILE 85.A O no hydrogen 2.891 N/A LYS 78.A NZ GLU 285.A OE1 no hydrogen 3.232 N/A LEU 79.A N ARG 288.A O no hydrogen 2.792 N/A THR 80.A N SER 83.A O no hydrogen 2.882 N/A SER 83.A N THR 80.A O no hydrogen 3.371 N/A ILE 85.A N LYS 78.A O no hydrogen 3.214 N/A GLN 87.A N CYS 76.A O no hydrogen 3.129 N/A LYS 91.A NZ GLU 240.A OE2 no hydrogen 2.838 N/A LYS 91.A NZ ALA 292.A O no hydrogen 3.044 N/A LYS 91.A NZ PRO 293.A O no hydrogen 2.814 N/A LEU 99.A N ILE 135.A O no hydrogen 2.795 N/A HIS 100.A N ALA 12.A O no hydrogen 3.166 N/A TYR 101.A N THR 132.A OG1 no hydrogen 3.088 N/A CYS 102.A N PHE 10.A O no hydrogen 2.690 N/A CYS 102.A SG HIS 100.A O no hydrogen 4.046 N/A ALA 103.A N GLN 130.A O no hydrogen 2.871 N/A PHE 107.A N PRO 104.A O no hydrogen 3.283 N/A ALA 108.A N VAL 343.A O no hydrogen 3.059 N/A ILE 109.A N VAL 129.A O no hydrogen 2.979 N/A LEU 110.A N LYS 341.A O no hydrogen 2.799 N/A LYS 111.A N SER 127.A O no hydrogen 3.134 N/A LYS 111.A NZ GLU 40.A OE2 no hydrogen 3.177 N/A CYS 112.A N LYS 339.A O no hydrogen 2.998 N/A ASN 113.A N ASN 125.A O no hydrogen 2.920 N/A LYS 115.A NZ GLU 151.A OE1 no hydrogen 3.098 N/A THR 116.A N ASN 114.A OD1 no hydrogen 2.822 N/A PHE 117.A N ASN 114.A O no hydrogen 3.056 N/A THR 120.A N ASN 118.A OD1 no hydrogen 3.059 N/A THR 120.A OG1 ASN 118.A OD1 no hydrogen 3.296 N/A CYS 123.A SG ASN 125.A O no hydrogen 3.758 N/A THR 128.A N SER 127.A OG no hydrogen 2.850 N/A VAL 129.A N ILE 109.A O no hydrogen 3.198 N/A CYS 131.A SG ASP 35.A OD2 no hydrogen 3.600 N/A THR 132.A N TYR 101.A O no hydrogen 2.912 N/A THR 132.A OG1 HIS 133.A O no hydrogen 3.000 N/A HIS 133.A N TYR 340.A OH no hydrogen 3.108 N/A HIS 133.A ND1 TYR 340.A OH no hydrogen 2.668 N/A ILE 135.A N LEU 99.A O no hydrogen 3.245 N/A VAL 138.A N LYS 136.A O no hydrogen 2.724 N/A SER 140.A OG LEU 143.A O no hydrogen 2.814 N/A THR 141.A N SER 234.A O no hydrogen 3.042 N/A THR 141.A OG1 GLU 229.A O no hydrogen 2.710 N/A THR 141.A OG1 THR 232.A O no hydrogen 2.920 N/A THR 141.A OG1 SER 234.A OG no hydrogen 3.042 N/A GLN 142.A NE2 ILE 230.A O no hydrogen 2.731 N/A LEU 143.A N THR 141.A O no hydrogen 2.589 N/A LEU 144.A N GLY 307.A O no hydrogen 2.711 N/A ASN 146.A N ASN 304.A O no hydrogen 2.864 N/A GLY 147.A N THR 306.A OG1 no hydrogen 3.165 N/A SER 148.A N GLU 336.A OE2 no hydrogen 3.184 N/A SER 148.A OG GLU 336.A OE1 no hydrogen 2.927 N/A ALA 150.A N LEU 172.A O no hydrogen 2.928 N/A ILE 155.A N HIS 171.A O no hydrogen 3.317 N/A ARG 157.A N ILE 169.A O no hydrogen 2.773 N/A ARG 157.A NH1 PHE 117.A O no hydrogen 2.791 N/A ARG 157.A NH2 HIS 171.A ND1 no hydrogen 2.950 N/A SER 158.A OG ASN 160.A O no hydrogen 3.234 N/A THR 162.A N ASN 160.A OD1 no hydrogen 2.928 N/A THR 162.A OG1 ASN 160.A OD1 no hydrogen 2.774 N/A ASN 163.A N ASN 160.A OD1 no hydrogen 3.273 N/A ASN 164.A ND2 ASP 313.A O no hydrogen 2.677 N/A LYS 166.A N ASN 163.A O no hydrogen 2.977 N/A LYS 166.A NZ GLU 159.A OE2 no hydrogen 3.291 N/A ILE 168.A N LEU 310.A O no hydrogen 3.055 N/A ILE 169.A N ARG 157.A O no hydrogen 2.624 N/A VAL 170.A N LEU 308.A O no hydrogen 2.869 N/A HIS 171.A N ILE 155.A O no hydrogen 2.867 N/A HIS 171.A NE2 SER 148.A O no hydrogen 2.593 N/A LEU 172.A N THR 306.A O no hydrogen 3.002 N/A ASN 173.A ND2 GLU 152.A O no hydrogen 3.012 N/A VAL 176.A N ILE 305.A O no hydrogen 3.037 N/A ASN 177.A ND2 ASN 302.A OD1 no hydrogen 2.735 N/A ASN 177.A ND2 ASN 304.A OD1 no hydrogen 3.230 N/A ILE 178.A N SER 303.A O no hydrogen 2.892 N/A VAL 179.A N ASN 192.A O no hydrogen 3.270 N/A CYS 180.A N CYS 301.A O no hydrogen 3.030 N/A THR 181.A N HIS 190.A O no hydrogen 2.821 N/A ARG 182.A N ILE 299.A O no hydrogen 2.797 N/A ARG 182.A NE ARG 182.A O no hydrogen 2.897 N/A ARG 182.A NH1 ILE 186.A O no hydrogen 2.594 N/A ARG 182.A NH2 ILE 295.A O no hydrogen 2.915 N/A ARG 182.A NH2 GLY 297.A O no hydrogen 2.775 N/A ARG 187.A N ASN 185.A OD1 no hydrogen 2.826 N/A ARG 187.A NE ILE 276.A O no hydrogen 3.448 N/A GLN 188.A N ASN 185.A O no hydrogen 3.302 N/A ALA 189.A N CYS 274.A O no hydrogen 3.039 N/A HIS 190.A N THR 181.A O no hydrogen 3.059 N/A CYS 191.A N LEU 272.A O no hydrogen 2.923 N/A ASN 192.A N VAL 179.A O no hydrogen 2.957 N/A ILE 193.A N ILE 270.A O no hydrogen 2.867 N/A GLU 195.A N GLY 268.A O no hydrogen 3.410 N/A SER 196.A OG ASN 194.A OD1 no hydrogen 2.427 N/A LYS 197.A N ASN 194.A O no hydrogen 3.145 N/A LYS 197.A N ASN 194.A OD1 no hydrogen 2.796 N/A TRP 198.A N ASN 194.A O no hydrogen 3.020 N/A TRP 198.A NE1 LEU 249.A O no hydrogen 3.008 N/A ASN 199.A N GLU 195.A O no hydrogen 2.598 N/A ASN 200.A N SER 196.A O no hydrogen 3.214 N/A THR 201.A N LYS 197.A O no hydrogen 3.229 N/A THR 201.A OG1 LYS 197.A O no hydrogen 2.768 N/A LEU 202.A N TRP 198.A O no hydrogen 3.206 N/A GLN 203.A N ASN 199.A O no hydrogen 3.068 N/A GLN 203.A N ASN 200.A O no hydrogen 3.241 N/A GLN 203.A NE2 GLY 257.A O no hydrogen 3.116 N/A LYS 204.A N ASN 200.A O no hydrogen 3.097 N/A VAL 205.A N THR 201.A O no hydrogen 2.908 N/A GLY 206.A N LEU 202.A O no hydrogen 2.782 N/A GLU 207.A N GLN 203.A O no hydrogen 2.835 N/A GLU 208.A N LYS 204.A O no hydrogen 2.922 N/A LEU 209.A N VAL 205.A O no hydrogen 2.920 N/A ALA 210.A N GLY 206.A O no hydrogen 2.906 N/A LYS 211.A N GLU 207.A O no hydrogen 3.043 N/A HIS 212.A N LEU 209.A O no hydrogen 2.841 N/A HIS 212.A ND1 GLU 208.A O no hydrogen 3.021 N/A PHE 213.A N ALA 210.A O no hydrogen 3.001 N/A SER 215.A N PHE 213.A O no hydrogen 2.549 N/A LYS 216.A NZ GLU 320.A OE2 no hydrogen 3.134 N/A THR 217.A N ASP 318.A O no hydrogen 2.812 N/A THR 217.A OG1 ASP 318.A O no hydrogen 2.992 N/A LYS 219.A N GLU 320.A O no hydrogen 2.863 N/A PHE 220.A N GLY 252.A O no hydrogen 2.759 N/A GLU 221.A N PHE 322.A O no hydrogen 2.918 N/A ILE 230.A N ASP 227.A O no hydrogen 2.921 N/A THR 231.A N ASP 227.A O no hydrogen 2.919 N/A THR 231.A OG1 ASP 227.A O no hydrogen 3.340 N/A THR 232.A OG1 LEU 228.A O no hydrogen 2.637 N/A HIS 233.A N CYS 244.A O no hydrogen 3.054 N/A HIS 233.A ND1 THR 141.A O no hydrogen 2.750 N/A SER 234.A N THR 141.A OG1 no hydrogen 3.083 N/A SER 234.A OG THR 141.A OG1 no hydrogen 3.042 N/A SER 234.A OG GLU 229.A O no hydrogen 3.026 N/A PHE 235.A N PHE 242.A O no hydrogen 3.075 N/A CYS 237.A N GLU 240.A O no hydrogen 2.850 N/A GLY 239.A N ASN 236.A OD1 no hydrogen 2.853 N/A GLU 240.A N CYS 237.A O no hydrogen 2.951 N/A PHE 242.A N PHE 235.A O no hydrogen 2.827 N/A TYR 243.A N LYS 275.A O no hydrogen 2.825 N/A TYR 243.A OH GLU 229.A OE2 no hydrogen 2.935 N/A CYS 244.A N HIS 233.A O no hydrogen 2.860 N/A ASN 245.A N GLN 273.A O no hydrogen 2.837 N/A SER 247.A N ASN 245.A OD1 no hydrogen 3.014 N/A SER 247.A OG ASN 245.A OD1 no hydrogen 2.893 N/A LEU 249.A N THR 246.A O no hydrogen 3.013 N/A PHE 250.A N THR 246.A O no hydrogen 3.353 N/A ASN 251.A ND2 SER 247.A O no hydrogen 2.868 N/A GLY 252.A N PHE 220.A O no hydrogen 3.299 N/A THR 253.A N ASN 260.A O no hydrogen 3.180 N/A TYR 254.A N ILE 218.A O no hydrogen 3.024 N/A THR 258.A N ARG 255.A O no hydrogen 3.435 N/A THR 258.A OG1 ARG 255.A O no hydrogen 2.494 N/A TYR 259.A OH TRP 198.A O no hydrogen 3.176 N/A TYR 259.A OH ASN 199.A OD1 no hydrogen 3.142 N/A ASN 260.A N THR 253.A O no hydrogen 3.303 N/A HIS 261.A NE2 LEU 249.A O no hydrogen 2.932 N/A THR 262.A OG1 ASN 251.A O no hydrogen 3.279 N/A ARG 264.A NH1 HIS 261.A O no hydrogen 2.883 N/A SER 265.A N GLU 195.A OE2 no hydrogen 3.093 N/A SER 265.A OG THR 269.A O no hydrogen 2.548 N/A GLY 268.A N SER 265.A O no hydrogen 2.665 N/A THR 269.A OG1 SER 265.A OG no hydrogen 3.430 N/A ILE 270.A N ILE 193.A O no hydrogen 2.626 N/A THR 271.A OG1 ASN 192.A OD1 no hydrogen 3.029 N/A LEU 272.A N CYS 191.A O no hydrogen 2.796 N/A CYS 274.A N ALA 189.A O no hydrogen 2.667 N/A CYS 274.A SG LEU 272.A O no hydrogen 3.734 N/A LYS 275.A N TYR 243.A O no hydrogen 2.990 N/A ILE 276.A N ARG 187.A O no hydrogen 2.941 N/A LYS 277.A N PHE 241.A O no hydrogen 3.099 N/A LYS 277.A NZ ILE 279.A O no hydrogen 3.315 N/A ILE 280.A N ALA 289.A O no hydrogen 2.922 N/A ASN 281.A N GLU 229.A OE2 no hydrogen 3.190 N/A ASN 281.A ND2 GLU 229.A OE1 no hydrogen 2.851 N/A MET 282.A N GLY 287.A O no hydrogen 2.928 N/A TRP 283.A N GLN 284.A OE1 no hydrogen 3.064 N/A GLN 284.A N GLN 284.A OE1 no hydrogen 2.753 N/A ARG 288.A N LEU 79.A O no hydrogen 2.855 N/A ALA 289.A N ILE 280.A O no hydrogen 2.859 N/A ILE 290.A N VAL 77.A O no hydrogen 2.712 N/A TYR 291.A N GLN 278.A O no hydrogen 2.825 N/A ILE 295.A N GLU 240.A OE2 no hydrogen 3.164 N/A ILE 299.A N ARG 182.A O no hydrogen 3.245 N/A CYS 301.A N CYS 180.A O no hydrogen 2.702 N/A CYS 301.A SG THR 300.A O no hydrogen 3.680 N/A SER 303.A N ILE 178.A O no hydrogen 2.935 N/A ASN 304.A N ASN 146.A OD1 no hydrogen 3.144 N/A ILE 305.A N VAL 176.A O no hydrogen 2.716 N/A THR 306.A N LEU 144.A O no hydrogen 2.941 N/A THR 306.A OG1 LEU 144.A O no hydrogen 3.472 N/A LEU 308.A N VAL 170.A O no hydrogen 2.809 N/A LEU 309.A N GLN 142.A O no hydrogen 3.088 N/A LEU 310.A N ILE 168.A O no hydrogen 2.739 N/A ARG 312.A NH1 GLU 320.A OE1 no hydrogen 3.084 N/A ARG 312.A NH2 LEU 161.A O no hydrogen 3.258 N/A ASP 313.A N THR 321.A O no hydrogen 2.966 N/A GLU 320.A N THR 217.A O no hydrogen 2.633 N/A PHE 322.A N LYS 219.A O no hydrogen 2.835 N/A ARG 323.A N LEU 311.A O no hydrogen 3.026 N/A ARG 323.A NE ASP 313.A OD1 no hydrogen 3.429 N/A ARG 323.A NE ASP 313.A OD2 no hydrogen 3.196 N/A ARG 323.A NH1 PRO 222.A O no hydrogen 2.706 N/A ARG 323.A NH2 ASP 313.A OD2 no hydrogen 3.484 N/A GLY 325.A N LEU 309.A O no hydrogen 2.842 N/A ASP 331.A N ASP 328.A O no hydrogen 3.016 N/A ASN 332.A N MET 329.A O no hydrogen 2.923 N/A ASN 332.A ND2 VAL 138.A O no hydrogen 3.551 N/A ASN 332.A ND2 SER 140.A O no hydrogen 2.783 N/A TRP 333.A N ARG 330.A O no hydrogen 3.038 N/A ARG 334.A N ARG 330.A O no hydrogen 3.039 N/A ARG 334.A NE MET 52.A O no hydrogen 3.106 N/A ARG 334.A NH1 ASP 331.A OD1 no hydrogen 3.499 N/A SER 335.A N ASP 331.A O no hydrogen 3.314 N/A SER 335.A OG ASP 331.A O no hydrogen 3.512 N/A SER 335.A OG ASN 332.A O no hydrogen 2.915 N/A GLU 336.A N TRP 333.A O no hydrogen 3.312 N/A LEU 337.A N TRP 333.A O no hydrogen 2.863 N/A TYR 340.A N LEU 337.A O no hydrogen 3.232 N/A TYR 340.A OH HIS 133.A ND1 no hydrogen 2.668 N/A LYS 341.A N LEU 110.A O no hydrogen 3.100 N/A LYS 341.A NZ GLU 4.A OE2 no hydrogen 3.056 N/A VAL 343.A N ALA 108.A O no hydrogen 2.961 N/A ILE 345.A N GLY 106.A O no hydrogen 3.154 N/A