Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3tlg_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 2.A N GLY 125.A O no hydrogen 3.128 N/A LEU 7.A N LEU 156.A O no hydrogen 2.992 N/A ALA 8.A N ASP 11.A OD2 no hydrogen 2.841 N/A ASP 11.A N ALA 8.A O no hydrogen 2.985 N/A ILE 13.A N LYS 43.A O no hydrogen 2.767 N/A GLY 14.A N CYS 79.A O no hydrogen 2.894 N/A PHE 15.A N VAL 45.A O no hydrogen 2.991 N/A SER 17.A N GLU 67.A OE1 no hydrogen 2.772 N/A SER 17.A OG THR 82.A OG1 no hydrogen 2.801 N/A SER 18.A OG SER 88.A OG no hydrogen 2.670 N/A ALA 20.A N GLY 84.A O no hydrogen 3.007 N/A VAL 24.A N PRO 21.A O no hydrogen 3.027 N/A THR 25.A N PRO 21.A O no hydrogen 3.182 N/A THR 25.A OG1 PRO 21.A O no hydrogen 3.554 N/A ALA 26.A N ALA 22.A O no hydrogen 2.839 N/A ASN 28.A ND2 ASN 180.A O no hydrogen 2.854 N/A ARG 29.A N ASN 180.A OD1 no hydrogen 3.012 N/A ARG 29.A NE ILE 135.A O no hydrogen 2.937 N/A ARG 29.A NH1 TRP 179.A O no hydrogen 3.025 N/A ARG 29.A NH2 PRO 136.A O no hydrogen 2.803 N/A ARG 29.A NH2 GLU 140.A OE1 no hydrogen 2.803 N/A PHE 30.A N ALA 26.A O no hydrogen 2.897 N/A PHE 31.A N LYS 27.A O no hydrogen 2.933 N/A ARG 32.A N ASN 28.A O no hydrogen 3.089 N/A ARG 32.A NH1 GLY 139.A O no hydrogen 2.921 N/A ARG 32.A NH2 GLU 181.A O no hydrogen 2.391 N/A GLY 33.A N ARG 29.A O no hydrogen 3.004 N/A VAL 34.A N PHE 30.A O no hydrogen 2.971 N/A GLU 35.A N PHE 31.A O no hydrogen 2.921 N/A PHE 36.A N ARG 32.A O no hydrogen 2.911 N/A LEU 37.A N GLY 33.A O no hydrogen 3.128 N/A GLN 38.A N VAL 34.A O no hydrogen 2.952 N/A ARG 39.A N GLU 35.A O no hydrogen 2.928 N/A LYS 40.A N PHE 36.A O no hydrogen 3.325 N/A GLY 41.A N GLN 38.A O no hydrogen 2.925 N/A PHE 42.A N LEU 37.A O no hydrogen 3.197 N/A LYS 43.A N ASP 11.A O no hydrogen 3.089 N/A VAL 45.A N ILE 13.A O no hydrogen 2.836 N/A GLY 47.A N PHE 15.A O no hydrogen 2.765 N/A LYS 48.A NZ GLU 63.A OE1 no hydrogen 3.245 N/A LYS 48.A NZ GLU 63.A OE2 no hydrogen 3.499 N/A LYS 48.A NZ GLN 66.A OE1 no hydrogen 2.772 N/A LYS 48.A NZ GLU 70.A OE2 no hydrogen 3.335 N/A LEU 49.A N GLU 67.A OE2 no hydrogen 2.893 N/A THR 50.A N GLY 47.A O no hydrogen 3.029 N/A THR 50.A OG1 GLY 47.A O no hydrogen 2.868 N/A GLY 51.A N THR 23.A OG1 no hydrogen 2.917 N/A LYS 52.A N LEU 49.A O no hydrogen 3.011 N/A ASP 54.A N ARG 57.A O no hydrogen 2.730 N/A ARG 57.A N ASP 54.A O no hydrogen 3.230 N/A ARG 57.A NE ASP 54.A OD2 no hydrogen 2.869 N/A ARG 57.A NH2 ASP 54.A OD2 no hydrogen 3.311 N/A SER 58.A N SER 19.A O no hydrogen 2.934 N/A SER 58.A OG SER 17.A O no hydrogen 2.672 N/A GLU 63.A N THR 60.A OG1 no hydrogen 3.031 N/A ARG 64.A N THR 60.A O no hydrogen 2.964 N/A ARG 64.A NE GLY 59.A O no hydrogen 2.909 N/A ARG 64.A NE THR 60.A O no hydrogen 3.353 N/A ARG 64.A NH1 SER 18.A O no hydrogen 2.901 N/A ARG 64.A NH1 ASN 87.A O no hydrogen 3.023 N/A ALA 65.A N ILE 61.A O no hydrogen 3.072 N/A GLN 66.A N LYS 62.A O no hydrogen 2.899 N/A GLU 67.A N GLU 63.A O no hydrogen 2.902 N/A PHE 68.A N ARG 64.A O no hydrogen 3.205 N/A ASN 69.A N ALA 65.A O no hydrogen 2.911 N/A ASN 69.A ND2 PHE 94.A O no hydrogen 3.107 N/A GLU 70.A N GLN 66.A O no hydrogen 2.885 N/A LEU 71.A N PHE 68.A O no hydrogen 3.019 N/A VAL 72.A N PHE 68.A O no hydrogen 3.211 N/A TYR 73.A N ASN 69.A O no hydrogen 2.987 N/A TYR 73.A OH ASP 96.A OD2 no hydrogen 2.559 N/A ASN 74.A N LEU 71.A O no hydrogen 3.266 N/A ASP 76.A N ASN 74.A OD1 no hydrogen 2.925 N/A ILE 77.A N ASN 74.A O no hydrogen 3.286 N/A THR 78.A N THR 12.A O no hydrogen 3.053 N/A THR 78.A OG1 ASP 11.A OD2 no hydrogen 3.085 N/A CYS 79.A SG ILE 106.A O no hydrogen 4.015 N/A ILE 80.A N ILE 106.A O no hydrogen 2.700 N/A SER 81.A OG THR 113.A OG1 no hydrogen 3.215 N/A THR 82.A N PHE 16.A O no hydrogen 2.878 N/A THR 82.A OG1 PHE 16.A O no hydrogen 3.255 N/A THR 82.A OG1 SER 17.A OG no hydrogen 2.801 N/A ASP 86.A N SER 19.A OG no hydrogen 2.779 N/A ASN 87.A N SER 19.A OG no hydrogen 2.932 N/A SER 88.A N ASP 112.A OD2 no hydrogen 2.796 N/A SER 88.A OG SER 18.A OG no hydrogen 2.670 N/A SER 88.A OG ASP 112.A OD2 no hydrogen 2.594 N/A ASN 89.A ND2 GLY 215.A O no hydrogen 2.986 N/A SER 90.A N ASN 87.A O no hydrogen 3.178 N/A LEU 91.A N SER 88.A O no hydrogen 2.993 N/A LEU 92.A N ASN 89.A O no hydrogen 3.251 N/A PHE 94.A N LEU 91.A O no hydrogen 2.824 N/A ASP 96.A N ASN 69.A OD1 no hydrogen 2.866 N/A TYR 97.A N LEU 95.A O no hydrogen 3.098 N/A TYR 97.A OH LEU 92.A O no hydrogen 2.643 N/A ALA 99.A N ASP 96.A OD1 no hydrogen 3.011 N/A ILE 100.A N ASP 96.A O no hydrogen 3.107 N/A ILE 101.A N TYR 97.A O no hydrogen 3.002 N/A ALA 102.A N ASP 98.A O no hydrogen 2.962 N/A ASN 103.A N ALA 99.A O no hydrogen 3.010 N/A LYS 105.A NZ ASN 74.A O no hydrogen 3.194 N/A LYS 105.A NZ ILE 77.A O no hydrogen 2.613 N/A ILE 106.A N THR 78.A O no hydrogen 3.136 N/A ILE 108.A N ILE 80.A O no hydrogen 2.978 N/A GLY 109.A N PHE 129.A O no hydrogen 3.329 N/A SER 111.A N TYR 130.A OH no hydrogen 2.873 N/A THR 113.A N TYR 110.A O no hydrogen 3.045 N/A THR 113.A OG1 SER 81.A OG no hydrogen 3.215 N/A THR 113.A OG1 TYR 110.A O no hydrogen 3.148 N/A THR 114.A N SER 111.A O no hydrogen 2.864 N/A THR 114.A OG1 SER 111.A O no hydrogen 2.688 N/A ALA 115.A N ASP 112.A O no hydrogen 3.109 N/A LEU 117.A N THR 113.A O no hydrogen 3.043 N/A ALA 118.A N THR 114.A O no hydrogen 2.869 N/A GLY 119.A N ALA 115.A O no hydrogen 2.936 N/A ILE 120.A N LEU 116.A O no hydrogen 2.821 N/A TYR 121.A N LEU 117.A O no hydrogen 3.154 N/A ALA 122.A N ALA 118.A O no hydrogen 2.858 N/A LYS 123.A N GLY 119.A O no hydrogen 3.062 N/A LYS 123.A NZ GLU 220.A OE2 no hydrogen 3.033 N/A THR 124.A N ILE 120.A O no hydrogen 2.900 N/A THR 124.A OG1 ILE 120.A O no hydrogen 2.703 N/A GLY 125.A N TYR 121.A O no hydrogen 2.843 N/A LEU 126.A N THR 124.A OG1 no hydrogen 3.033 N/A ILE 127.A N LEU 2.A O no hydrogen 3.031 N/A THR 128.A OG1 LEU 117.A O no hydrogen 3.531 N/A PHE 129.A N ILE 107.A O no hydrogen 2.972 N/A TYR 130.A N LEU 307.A O no hydrogen 2.808 N/A TYR 130.A OH GLU 233.A OE2 no hydrogen 2.470 N/A GLY 131.A N GLY 109.A O no hydrogen 2.973 N/A ALA 133.A N SER 137.A OG no hydrogen 3.051 N/A LEU 134.A N SER 81.A O no hydrogen 2.820 N/A ILE 135.A N THR 82.A O no hydrogen 2.914 N/A SER 137.A N ALA 133.A O no hydrogen 2.965 N/A PHE 138.A N LEU 134.A O no hydrogen 3.081 N/A GLY 139.A N ILE 135.A O no hydrogen 3.144 N/A VAL 145.A N HIS 141.A O no hydrogen 3.499 N/A ASP 146.A N PRO 143.A O no hydrogen 3.108 N/A ILE 147.A N LEU 144.A O no hydrogen 3.113 N/A THR 148.A N LEU 144.A O no hydrogen 3.197 N/A THR 148.A OG1 LEU 144.A O no hydrogen 3.468 N/A TYR 149.A N VAL 145.A O no hydrogen 2.900 N/A GLU 150.A N ASP 146.A O no hydrogen 2.945 N/A SER 151.A N ILE 147.A O no hydrogen 3.253 N/A PHE 152.A N THR 148.A O no hydrogen 3.089 N/A ILE 153.A N TYR 149.A O no hydrogen 2.895 N/A LYS 154.A N GLU 150.A O no hydrogen 3.043 N/A ILE 155.A N SER 151.A O no hydrogen 2.893 N/A LEU 156.A N PHE 152.A O no hydrogen 3.120 N/A THR 157.A N ILE 153.A O no hydrogen 3.013 N/A THR 157.A OG1 ILE 153.A O no hydrogen 2.586 N/A ARG 158.A N LYS 154.A O no hydrogen 3.059 N/A ARG 158.A NH1 TYR 328.A OH no hydrogen 3.218 N/A ARG 158.A NH2 GLY 162.A O no hydrogen 3.122 N/A TYR 164.A N ILE 324.A O no hydrogen 2.978 N/A THR 165.A OG1 SER 323.A OG no hydrogen 2.741 N/A TYR 166.A N ILE 322.A O no hydrogen 2.945 N/A TYR 166.A OH THR 306.A O no hydrogen 2.601 N/A TRP 172.A N TYR 189.A O no hydrogen 3.047 N/A TRP 172.A NE1 LYS 190.A O no hydrogen 3.030 N/A SER 173.A N HIS 302.A O no hydrogen 2.784 N/A SER 173.A OG LYS 187.A O no hydrogen 2.676 N/A GLU 175.A N SER 173.A OG no hydrogen 3.128 N/A ILE 177.A N GLU 175.A O no hydrogen 3.039 N/A ASN 178.A ND2 ARG 184.A O no hydrogen 2.975 N/A GLU 181.A N GLU 181.A OE1 no hydrogen 2.602 N/A ARG 184.A NH1 GLU 175.A OE2 no hydrogen 2.517 N/A ARG 184.A NH2 GLU 175.A OE1 no hydrogen 3.003 N/A ARG 184.A NH2 PRO 185.A O no hydrogen 3.118 N/A LYS 186.A NZ GLU 140.A OE1 no hydrogen 2.961 N/A LYS 186.A NZ GLU 140.A OE2 no hydrogen 2.867 N/A LYS 187.A N GLU 175.A OE1 no hydrogen 2.918 N/A TYR 189.A N TRP 172.A O no hydrogen 2.865 N/A ASN 191.A ND2 PRO 169.A O no hydrogen 2.872 N/A ASN 191.A ND2 ASP 297.A OD2 no hydrogen 2.835 N/A CYS 193.A N ASN 191.A OD1 no hydrogen 3.078 N/A CYS 193.A SG ASP 294.A O no hydrogen 3.636 N/A ALA 194.A N ASP 294.A O no hydrogen 2.801 N/A TYR 196.A N VAL 292.A O no hydrogen 2.820 N/A GLY 199.A N ASP 318.A OD1 no hydrogen 3.000 N/A GLY 199.A N ASP 318.A OD2 no hydrogen 3.104 N/A VAL 201.A N ILE 315.A O no hydrogen 2.900 N/A GLY 203.A N LEU 313.A O no hydrogen 3.008 N/A ARG 204.A NE ASP 228.A OD1 no hydrogen 2.983 N/A ARG 204.A NH1 TYR 121.A OH no hydrogen 2.886 N/A ARG 204.A NH2 GLU 223.A O no hydrogen 2.946 N/A ARG 204.A NH2 ASP 228.A OD1 no hydrogen 3.333 N/A ARG 204.A NH2 ASP 228.A OD2 no hydrogen 2.727 N/A VAL 205.A N VAL 311.A O no hydrogen 2.954 N/A ILE 206.A N ILE 229.A O no hydrogen 2.993 N/A GLY 208.A N PHE 231.A O no hydrogen 2.850 N/A ASN 209.A N THR 114.A OG1 no hydrogen 2.977 N/A ASN 209.A ND2 GLU 233.A OE2 no hydrogen 2.954 N/A LEU 210.A N GLU 233.A O no hydrogen 3.038 N/A ASN 211.A N ASP 234.A OD1 no hydrogen 2.892 N/A THR 212.A N ASN 209.A OD1 no hydrogen 3.011 N/A THR 212.A OG1 SER 111.A O no hydrogen 3.429 N/A THR 212.A OG1 ASN 209.A OD1 no hydrogen 2.788 N/A LEU 213.A N ASN 209.A O no hydrogen 3.107 N/A THR 214.A N ASN 211.A O no hydrogen 3.207 N/A THR 214.A OG1 ASN 211.A O no hydrogen 2.607 N/A GLY 215.A N THR 212.A O no hydrogen 2.942 N/A ILE 216.A N LEU 213.A O no hydrogen 3.102 N/A TRP 217.A NE1 ASN 251.A OD1 no hydrogen 2.841 N/A SER 219.A N ILE 216.A O no hydrogen 3.129 N/A SER 219.A OG ILE 216.A O no hydrogen 2.737 N/A TRP 221.A N SER 219.A OG no hydrogen 3.082 N/A ARG 225.A N ASP 228.A OD2 no hydrogen 2.792 N/A GLY 227.A N LYS 256.A O no hydrogen 2.859 N/A ASP 228.A N ARG 225.A O no hydrogen 3.000 N/A ILE 229.A N ARG 204.A O no hydrogen 2.756 N/A LEU 230.A N ALA 259.A O no hydrogen 3.038 N/A PHE 231.A N ILE 206.A O no hydrogen 2.849 N/A ILE 232.A N ILE 261.A O no hydrogen 2.962 N/A GLU 233.A N GLY 208.A O no hydrogen 3.078 N/A SER 235.A OG GLU 266.A OE1 no hydrogen 2.649 N/A ARG 236.A N GLU 266.A O no hydrogen 2.778 N/A ARG 236.A NH2 SER 176.A OG no hydrogen 2.830 N/A SER 238.A OG THR 241.A OG1 no hydrogen 3.187 N/A ILE 239.A N ASP 269.A O no hydrogen 2.828 N/A THR 241.A N SER 238.A OG no hydrogen 3.063 N/A THR 241.A OG1 SER 238.A OG no hydrogen 3.187 N/A VAL 242.A N SER 238.A O no hydrogen 2.990 N/A GLU 243.A N ILE 239.A O no hydrogen 2.937 N/A ARG 244.A N ALA 240.A O no hydrogen 3.086 N/A LEU 245.A N THR 241.A O no hydrogen 2.944 N/A PHE 246.A N VAL 242.A O no hydrogen 2.975 N/A SER 247.A N GLU 243.A O no hydrogen 2.888 N/A LYS 249.A N PHE 246.A O no hydrogen 3.045 N/A LYS 249.A NZ VAL 284.A O no hydrogen 2.997 N/A LEU 250.A N SER 247.A O no hydrogen 2.828 N/A ARG 252.A N LYS 249.A O no hydrogen 2.958 N/A VAL 253.A N LEU 248.A O no hydrogen 3.115 N/A ASP 255.A N ARG 252.A O no hydrogen 3.116 N/A LYS 256.A N VAL 253.A O no hydrogen 3.045 N/A LYS 256.A NZ ILE 224.A O no hydrogen 3.034 N/A VAL 257.A N VAL 253.A O no hydrogen 3.182 N/A SER 258.A N ASP 228.A O no hydrogen 2.850 N/A SER 258.A OG GLY 227.A O no hydrogen 2.953 N/A SER 258.A OG ASP 228.A O no hydrogen 3.330 N/A ILE 260.A N PRO 291.A O no hydrogen 3.005 N/A ILE 261.A N LEU 230.A O no hydrogen 2.736 N/A LEU 262.A N LEU 293.A O no hydrogen 2.827 N/A GLY 263.A N ILE 232.A O no hydrogen 2.889 N/A LYS 264.A N PHE 296.A O no hydrogen 3.054 N/A LYS 264.A NZ ASN 191.A OD1 no hydrogen 2.794 N/A LYS 264.A NZ GLY 295.A O no hydrogen 2.762 N/A LYS 264.A NZ ASP 297.A OD1 no hydrogen 2.775 N/A LYS 264.A NZ ASP 297.A OD2 no hydrogen 3.247 N/A LEU 267.A N ASP 174.A OD2 no hydrogen 2.881 N/A ASP 269.A N LYS 237.A O no hydrogen 2.967 N/A ALA 271.A N ASP 269.A OD1 no hydrogen 2.968 N/A SER 273.A N CYS 270.A O no hydrogen 2.968 N/A SER 273.A OG CYS 270.A O no hydrogen 2.713 N/A ARG 275.A N SER 273.A OG no hydrogen 3.066 N/A GLU 279.A N ARG 276.A O no hydrogen 2.998 N/A VAL 280.A N ARG 276.A O no hydrogen 3.396 N/A LEU 281.A N PRO 277.A O no hydrogen 2.890 N/A THR 282.A N TYR 278.A O no hydrogen 2.920 N/A THR 282.A OG1 TYR 278.A O no hydrogen 3.029 N/A GLU 283.A N GLU 279.A O no hydrogen 3.126 N/A VAL 284.A N VAL 280.A O no hydrogen 3.011 N/A LEU 285.A N LEU 281.A O no hydrogen 2.805 N/A ASP 286.A N GLU 283.A O no hydrogen 3.170 N/A LYS 288.A N LEU 285.A O no hydrogen 3.139 N/A ILE 290.A N LYS 288.A O no hydrogen 3.132 N/A VAL 292.A N TYR 196.A O no hydrogen 2.904 N/A LEU 293.A N ILE 260.A O no hydrogen 2.890 N/A ASP 294.A N ALA 194.A O no hydrogen 2.822 N/A GLY 295.A N LEU 262.A O no hydrogen 2.801 N/A PHE 296.A N LEU 262.A O no hydrogen 3.011 N/A CYS 298.A N PHE 296.A O no hydrogen 2.921 N/A CYS 298.A SG TYR 130.A O no hydrogen 3.704 N/A CYS 298.A SG LEU 305.A O no hydrogen 3.430 N/A SER 299.A OG LYS 264.A O no hydrogen 2.856 N/A HIS 300.A ND1 GLU 233.A OE1 no hydrogen 2.862 N/A THR 301.A N SER 299.A OG no hydrogen 3.297 N/A THR 301.A OG1 SER 299.A OG no hydrogen 3.050 N/A HIS 302.A N SER 173.A O no hydrogen 2.977 N/A MET 304.A N THR 148.A OG1 no hydrogen 2.982 N/A LEU 305.A N ASP 297.A O no hydrogen 2.770 N/A THR 306.A N SER 151.A OG no hydrogen 3.027 N/A LEU 307.A N TYR 130.A O no hydrogen 2.868 N/A LEU 309.A N THR 128.A O no hydrogen 2.882 N/A GLY 310.A N VAL 205.A O no hydrogen 2.830 N/A LYS 312.A N GLU 326.A OE1 no hydrogen 2.889 N/A LEU 313.A N GLY 203.A O no hydrogen 3.010 N/A ALA 314.A N SER 323.A O no hydrogen 2.799 N/A ILE 315.A N VAL 201.A O no hydrogen 2.753 N/A ASP 316.A N ASN 321.A O no hydrogen 2.838 N/A PHE 317.A N GLY 199.A O no hydrogen 2.852 N/A ASN 319.A N ASP 316.A OD1 no hydrogen 2.891 N/A ASN 321.A N ASP 316.A O no hydrogen 3.077 N/A SER 323.A N ALA 314.A O no hydrogen 2.877 N/A SER 323.A OG THR 165.A OG1 no hydrogen 2.741 N/A ILE 324.A N TYR 164.A O no hydrogen 2.795 N/A THR 325.A N LYS 312.A O no hydrogen 2.978 N/A THR 325.A OG1 GLU 202.A OE1 no hydrogen 2.658 N/A THR 325.A OG1 LYS 312.A O no hydrogen 3.378 N/A GLN 327.A NE2 LEU 329.A O no hydrogen 2.895 N/A TYR 328.A N GLN 160.A OE1 no hydrogen 2.906 N/A TYR 328.A OH ILE 155.A O no hydrogen 2.752 N/A SER 330.A N ALA 4.A O no hydrogen 2.757 N/A SER 330.A OG ALA 4.A O no hydrogen 3.520 N/A