Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3tz2_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 5.A OG1 PRO 4.A O no hydrogen 2.372 N/A MET 6.A N THR 3.A O no hydrogen 3.176 N/A LEU 8.A N ARG 1.A O no hydrogen 2.601 N/A SER 13.A OG SER 17.A OG no hydrogen 2.950 N/A GLY 16.A N SER 13.A O no hydrogen 3.183 N/A SER 17.A OG SER 13.A OG no hydrogen 2.950 N/A SER 17.A OG ASP 15.A OD1 no hydrogen 3.091 N/A LEU 19.A N GLY 16.A O no hydrogen 3.283 N/A SER 22.A N HIS 18.A O no hydrogen 2.769 N/A SER 22.A OG HIS 139.A ND1 no hydrogen 2.485 N/A GLY 23.A N LEU 19.A O no hydrogen 3.203 N/A ARG 24.A N LEU 20.A O no hydrogen 2.643 N/A TYR 25.A N LYS 21.A O no hydrogen 2.961 N/A LEU 26.A N SER 22.A O no hydrogen 2.876 N/A GLN 27.A N GLY 23.A O no hydrogen 2.832 N/A GLN 28.A N ARG 24.A O no hydrogen 3.343 N/A GLN 28.A NE2 GLU 29.A OE1 no hydrogen 3.214 N/A GLU 29.A N TYR 25.A O no hydrogen 2.829 N/A LEU 30.A N LEU 26.A O no hydrogen 2.776 N/A ARG 33.A N GLU 29.A O no hydrogen 3.054 N/A ILE 34.A N LEU 30.A O no hydrogen 2.911 N/A ALA 35.A N PRO 31.A O no hydrogen 2.906 N/A HIS 36.A N VAL 32.A O no hydrogen 3.083 N/A ARG 37.A N ILE 34.A O no hydrogen 2.839 N/A ARG 37.A NE SER 128.A OG no hydrogen 3.190 N/A ILE 38.A N ILE 34.A O no hydrogen 3.070 N/A LYS 39.A N ALA 35.A O no hydrogen 3.061 N/A GLY 40.A N HIS 36.A O no hydrogen 3.301 N/A PHE 41.A N ARG 37.A O no hydrogen 3.101 N/A ARG 42.A N ILE 38.A O no hydrogen 2.940 N/A SER 43.A N LYS 39.A O no hydrogen 2.907 N/A SER 43.A OG GLY 40.A O no hydrogen 2.941 N/A LEU 44.A N PHE 41.A O no hydrogen 3.279 N/A GLY 49.A N PRO 45.A O no hydrogen 2.993 N/A ASN 51.A N ILE 48.A O no hydrogen 2.815 N/A ASN 51.A ND2 GLU 107.A OE1 no hydrogen 3.067 N/A THR 53.A OG1 GLU 107.A OE2 no hydrogen 3.201 N/A LEU 55.A N ASN 51.A O no hydrogen 2.781 N/A HIS 56.A N PRO 52.A O no hydrogen 2.561 N/A VAL 57.A N THR 53.A O no hydrogen 2.951 N/A HIS 58.A N ILE 54.A O no hydrogen 2.819 N/A GLU 59.A N LEU 55.A O no hydrogen 2.918 N/A LEU 60.A N HIS 56.A O no hydrogen 2.855 N/A TYR 61.A N VAL 57.A O no hydrogen 3.158 N/A ILE 62.A N HIS 58.A O no hydrogen 3.245 N/A ARG 63.A N GLU 59.A O no hydrogen 2.774 N/A ALA 64.A N LEU 60.A O no hydrogen 2.807 N/A PHE 65.A N TYR 61.A O no hydrogen 2.865 N/A GLN 66.A N ILE 62.A O no hydrogen 2.887 N/A LYS 67.A N ARG 63.A O no hydrogen 2.977 N/A LEU 68.A N ALA 64.A O no hydrogen 2.975 N/A THR 69.A N PHE 65.A O no hydrogen 3.126 N/A THR 69.A OG1 PHE 65.A O no hydrogen 2.670 N/A ASP 70.A N GLN 66.A O no hydrogen 2.803 N/A PHE 71.A N LYS 67.A O no hydrogen 3.119 N/A LYS 75.A N ASP 79.A OD2 no hydrogen 2.993 N/A ASP 79.A N ASP 76.A OD1 no hydrogen 2.789 N/A GLU 80.A N ASP 76.A O no hydrogen 3.406 N/A ALA 81.A N GLN 77.A O no hydrogen 2.865 N/A GLN 82.A N ALA 78.A O no hydrogen 3.120 N/A TYR 83.A N ASP 79.A O no hydrogen 2.811 N/A CYS 84.A N GLU 80.A O no hydrogen 2.932 N/A CYS 84.A SG GLU 80.A O no hydrogen 3.503 N/A CYS 84.A SG GLU 80.A OE2 no hydrogen 3.023 N/A CYS 84.A SG HIS 143.A NE2 no hydrogen 3.102 N/A LEU 86.A N GLN 82.A O no hydrogen 3.240 N/A VAL 87.A N TYR 83.A O no hydrogen 3.113 N/A ARG 88.A N CYS 84.A O no hydrogen 2.980 N/A GLN 89.A N GLN 85.A O no hydrogen 3.068 N/A LEU 90.A N LEU 86.A O no hydrogen 2.727 N/A LEU 91.A N VAL 87.A O no hydrogen 2.917 N/A ASP 92.A N ARG 88.A O no hydrogen 3.116 N/A ASP 93.A N GLN 89.A O no hydrogen 2.859 N/A HIS 94.A N LEU 90.A O no hydrogen 2.945 N/A LYS 95.A N ASP 92.A O no hydrogen 3.444 N/A VAL 97.A N HIS 94.A O no hydrogen 3.195 N/A THR 99.A N ASP 96.A O no hydrogen 2.981 N/A LEU 100.A N ASP 96.A O no hydrogen 3.143 N/A LEU 101.A N VAL 97.A O no hydrogen 2.863 N/A ALA 102.A N VAL 98.A O no hydrogen 3.288 N/A GLU 103.A N THR 99.A O no hydrogen 3.135 N/A GLY 104.A N LEU 100.A O no hydrogen 2.708 N/A LEU 105.A N LEU 101.A O no hydrogen 2.757 N/A ARG 106.A N ALA 102.A O no hydrogen 2.845 N/A GLU 107.A N GLU 103.A O no hydrogen 2.911 N/A SER 108.A N LEU 105.A O no hydrogen 2.973 N/A SER 108.A OG SER 108.A O no hydrogen 2.438 N/A ARG 109.A N ARG 106.A O no hydrogen 3.365 N/A ARG 109.A NE ARG 106.A O no hydrogen 3.122 N/A LYS 110.A NZ GLU 107.A O no hydrogen 3.076 N/A ILE 112.A N ARG 109.A O no hydrogen 2.962 N/A GLU 115.A N GLU 115.A OE1 no hydrogen 2.631 N/A VAL 118.A N GLU 115.A O no hydrogen 2.883 N/A ARG 119.A N GLU 115.A O no hydrogen 3.033 N/A ARG 119.A NH2 ASP 262.A OD1 no hydrogen 2.831 N/A TYR 120.A N LYS 116.A O no hydrogen 3.044 N/A PHE 121.A N LEU 117.A O no hydrogen 3.339 N/A LEU 122.A N VAL 118.A O no hydrogen 2.771 N/A ASP 123.A N ARG 119.A O no hydrogen 2.966 N/A LYS 124.A N TYR 120.A O no hydrogen 2.986 N/A THR 125.A N PHE 121.A O no hydrogen 2.868 N/A THR 125.A OG1 PHE 121.A O no hydrogen 2.747 N/A LEU 126.A N LEU 122.A O no hydrogen 2.740 N/A THR 127.A N ASP 123.A O no hydrogen 3.128 N/A THR 127.A OG1 ASP 123.A O no hydrogen 2.661 N/A THR 127.A OG1 LYS 124.A O no hydrogen 3.534 N/A SER 128.A N LYS 124.A O no hydrogen 3.056 N/A ARG 129.A N THR 125.A O no hydrogen 2.782 N/A ARG 129.A NH2 HIS 94.A O no hydrogen 2.810 N/A LEU 130.A N LEU 126.A O no hydrogen 3.036 N/A GLY 131.A N THR 127.A O no hydrogen 3.072 N/A ILE 132.A N SER 128.A O no hydrogen 3.132 N/A ARG 133.A N ARG 129.A O no hydrogen 2.958 N/A ARG 133.A NH1 LEU 91.A O no hydrogen 3.329 N/A ARG 133.A NH2 LEU 91.A O no hydrogen 2.919 N/A MET 134.A N LEU 130.A O no hydrogen 2.740 N/A LEU 135.A N GLY 131.A O no hydrogen 2.921 N/A ALA 136.A N ILE 132.A O no hydrogen 2.914 N/A THR 137.A N ARG 133.A O no hydrogen 2.978 N/A THR 137.A OG1 ARG 133.A O no hydrogen 2.844 N/A HIS 138.A N MET 134.A O no hydrogen 2.737 N/A HIS 138.A NE2 TYR 9.A O no hydrogen 3.033 N/A HIS 139.A N LEU 135.A O no hydrogen 3.174 N/A HIS 139.A ND1 SER 22.A OG no hydrogen 2.485 N/A HIS 139.A NE2 GLU 80.A OE2 no hydrogen 2.763 N/A LEU 140.A N ALA 136.A O no hydrogen 3.129 N/A ALA 141.A N THR 137.A O no hydrogen 2.746 N/A LEU 142.A N HIS 138.A O no hydrogen 3.046 N/A LEU 142.A N HIS 139.A O no hydrogen 2.850 N/A HIS 143.A N LEU 140.A O no hydrogen 3.173 N/A HIS 143.A NE2 GLU 80.A OE2 no hydrogen 2.695 N/A GLU 144.A N ALA 141.A O no hydrogen 2.909 N/A VAL 150.A N ILE 153.A O no hydrogen 2.900 N/A ILE 152.A N HIS 138.A ND1 no hydrogen 3.228 N/A ILE 153.A N VAL 150.A O no hydrogen 3.243 N/A CYS 154.A N PHE 196.A O no hydrogen 2.726 N/A CYS 154.A SG ASP 148.A O no hydrogen 3.716 N/A THR 155.A N ASP 148.A O no hydrogen 2.812 N/A LEU 157.A N PHE 194.A O no hydrogen 3.108 N/A LYS 160.A NZ GLU 164.A OE2 no hydrogen 2.423 N/A LYS 161.A N SER 158.A OG no hydrogen 3.024 N/A ILE 162.A N SER 158.A O no hydrogen 3.148 N/A ILE 163.A N PRO 159.A O no hydrogen 2.963 N/A GLU 164.A N LYS 160.A O no hydrogen 2.918 N/A LYS 165.A N LYS 161.A O no hydrogen 3.109 N/A LYS 165.A NZ ASP 202.A OD1 no hydrogen 3.484 N/A TRP 166.A N ILE 162.A O no hydrogen 3.295 N/A TRP 166.A NE1 ASP 202.A OD1 no hydrogen 2.704 N/A VAL 167.A N ILE 163.A O no hydrogen 2.799 N/A ASP 168.A N GLU 164.A O no hydrogen 3.010 N/A PHE 169.A N LYS 165.A O no hydrogen 3.184 N/A ALA 170.A N TRP 166.A O no hydrogen 2.872 N/A ARG 171.A N VAL 167.A O no hydrogen 2.537 N/A ARG 172.A N ASP 168.A O no hydrogen 3.020 N/A LEU 173.A N PHE 169.A O no hydrogen 3.253 N/A CYS 174.A N ALA 170.A O no hydrogen 2.978 N/A CYS 174.A SG ASN 180.A O no hydrogen 3.683 N/A GLU 175.A N ARG 171.A O no hydrogen 2.646 N/A HIS 176.A N ARG 172.A O no hydrogen 3.152 N/A LYS 177.A N CYS 174.A O no hydrogen 2.879 N/A TYR 178.A N CYS 174.A O no hydrogen 3.038 N/A TYR 178.A OH GLU 218.A OE2 no hydrogen 2.596 N/A GLY 179.A N GLU 175.A O no hydrogen 2.557 N/A ASN 180.A ND2 PRO 224.A O no hydrogen 2.924 N/A ARG 185.A N VAL 230.A O no hydrogen 2.897 N/A ARG 185.A NH1 ASP 229.A OD2 no hydrogen 3.192 N/A ASN 187.A N ILE 232.A O no hydrogen 2.782 N/A HIS 189.A N ILE 234.A O no hydrogen 2.862 N/A ALA 192.A N HIS 189.A O no hydrogen 3.455 N/A ARG 193.A NE ARG 156.A O no hydrogen 3.362 N/A PHE 194.A N LEU 157.A O no hydrogen 3.167 N/A PHE 196.A N CYS 154.A O no hydrogen 2.905 N/A ASP 202.A N PRO 198.A O no hydrogen 2.863 N/A TYR 203.A N MET 199.A O no hydrogen 3.301 N/A TYR 203.A N PRO 200.A O no hydrogen 2.891 N/A ILE 204.A N PRO 200.A O no hydrogen 3.165 N/A LEU 205.A N LEU 201.A O no hydrogen 3.079 N/A GLU 207.A N ILE 204.A O no hydrogen 2.728 N/A LEU 208.A N ILE 204.A O no hydrogen 3.166 N/A LEU 209.A N LEU 205.A O no hydrogen 2.862 N/A LYS 210.A N PRO 206.A O no hydrogen 3.082 N/A LYS 210.A NZ GLU 207.A OE2 no hydrogen 3.192 N/A ASN 211.A N GLU 207.A O no hydrogen 3.076 N/A ALA 212.A N LEU 208.A O no hydrogen 2.808 N/A MET 213.A N LEU 209.A O no hydrogen 2.918 N/A ARG 214.A N LYS 210.A O no hydrogen 2.852 N/A ALA 215.A N ASN 211.A O no hydrogen 2.828 N/A THR 216.A N ALA 212.A O no hydrogen 3.188 N/A THR 216.A OG1 ALA 212.A O no hydrogen 2.941 N/A MET 217.A N MET 213.A O no hydrogen 2.863 N/A GLU 218.A N ARG 214.A O no hydrogen 2.718 N/A SER 219.A N THR 216.A O no hydrogen 3.368 N/A SER 219.A OG ALA 215.A O no hydrogen 3.139 N/A SER 219.A OG THR 216.A O no hydrogen 3.043 N/A HIS 220.A N MET 217.A O no hydrogen 2.933 N/A THR 223.A OG1 ASN 226.A O no hydrogen 3.093 N/A ASN 226.A N THR 223.A O no hydrogen 2.794 N/A VAL 230.A N ARG 183.A O no hydrogen 2.950 N/A VAL 231.A N SER 246.A O no hydrogen 3.036 N/A ILE 232.A N ARG 185.A O no hydrogen 2.678 N/A THR 233.A N ARG 244.A O no hydrogen 2.889 N/A THR 233.A OG1 ASN 187.A OD1 no hydrogen 3.101 N/A ILE 234.A N ASN 187.A O no hydrogen 2.998 N/A ALA 235.A N ILE 242.A O no hydrogen 2.848 N/A ASN 236.A N HIS 189.A ND1 no hydrogen 2.815 N/A ASN 237.A N ASP 240.A O no hydrogen 3.373 N/A ASN 237.A ND2 ASP 240.A OD2 no hydrogen 3.329 N/A VAL 239.A N ASN 237.A OD1 no hydrogen 2.863 N/A ASP 240.A N ASN 237.A OD1 no hydrogen 2.889 N/A LEU 241.A N LEU 297.A O no hydrogen 2.936 N/A ILE 242.A N ALA 235.A O no hydrogen 2.846 N/A ILE 243.A N LEU 295.A O no hydrogen 2.885 N/A ARG 244.A N THR 233.A O no hydrogen 2.848 N/A ARG 244.A NH1 TYR 294.A OH no hydrogen 3.531 N/A ARG 244.A NH2 THR 233.A OG1 no hydrogen 3.416 N/A ILE 245.A N VAL 293.A O no hydrogen 2.801 N/A SER 246.A N VAL 231.A O no hydrogen 2.882 N/A ASP 247.A N THR 291.A O no hydrogen 2.908 N/A GLY 249.A N ASP 247.A OD2 no hydrogen 3.400 N/A GLY 250.A N ILE 289.A O no hydrogen 2.932 N/A LEU 257.A N HIS 254.A O no hydrogen 3.125 N/A VAL 260.A N ASP 256.A O no hydrogen 2.704 N/A TYR 263.A OH ASP 123.A OD1 no hydrogen 2.367 N/A THR 269.A OG1 PHE 265.A O no hydrogen 3.058 N/A SER 270.A N GLY 266.A O no hydrogen 3.212 N/A SER 270.A OG GLY 266.A O no hydrogen 3.072 N/A ARG 271.A N LEU 267.A O no hydrogen 2.884 N/A ALA 272.A N PRO 268.A O no hydrogen 3.066 N/A TYR 273.A N THR 269.A O no hydrogen 3.046 N/A ALA 274.A N SER 270.A O no hydrogen 2.979 N/A GLU 275.A N ARG 271.A O no hydrogen 2.980 N/A TYR 276.A N ALA 272.A O no hydrogen 2.894 N/A LEU 277.A N TYR 273.A O no hydrogen 3.220 N/A LEU 277.A N ALA 274.A O no hydrogen 3.158 N/A GLY 278.A N GLU 275.A O no hydrogen 2.834 N/A GLY 279.A N ALA 274.A O no hydrogen 2.874 N/A SER 280.A N ARG 296.A O no hydrogen 2.990 N/A GLN 282.A N TYR 294.A O no hydrogen 2.833 N/A GLN 284.A N ASP 292.A O no hydrogen 2.859 N/A SER 285.A OG ILE 252.A O no hydrogen 2.772 N/A LEU 286.A N GLY 290.A O no hydrogen 2.860 N/A GLN 287.A N GLN 287.A OE1 no hydrogen 2.910 N/A GLN 287.A NE2 ILE 252.A O no hydrogen 2.756 N/A GLY 288.A N GLY 250.A O no hydrogen 3.103 N/A ILE 289.A N LEU 286.A O no hydrogen 2.880 N/A GLY 290.A N LEU 286.A O no hydrogen 3.153 N/A THR 291.A N ASP 247.A O no hydrogen 3.258 N/A THR 291.A N ASP 247.A OD2 no hydrogen 3.203 N/A ASP 292.A N GLN 284.A O no hydrogen 2.890 N/A VAL 293.A N ILE 245.A O no hydrogen 2.973 N/A TYR 294.A N GLN 282.A O no hydrogen 2.834 N/A LEU 295.A N ILE 243.A O no hydrogen 3.046 N/A ARG 296.A N SER 280.A O no hydrogen 3.097 N/A ARG 296.A NH1.B ASP 240.A OD1 no hydrogen 2.591 N/A LEU 297.A N LEU 241.A O no hydrogen 3.042 N/A ARG 298.A NE GLY 278.A O no hydrogen 2.987 N/A HIS 299.A N VAL 239.A O no hydrogen 3.064 N/A HIS 299.A NE2 ASN 236.A OD1 no hydrogen 2.692 N/A