Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3vo1_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 1.A OG GLU 5.A OE1 no hydrogen 3.340 N/A SER 1.A OG GLU 288.A OE1 no hydrogen 3.042 N/A LYS 2.A N GLU 288.A OE2 no hydrogen 3.076 N/A LYS 2.A NZ SER 287.A O no hydrogen 2.766 N/A LYS 3.A N SER 1.A OG no hydrogen 2.953 N/A LYS 3.A NZ TYR 251.A OH no hydrogen 3.526 N/A LYS 3.A NZ GLU 288.A O no hydrogen 3.163 N/A LYS 3.A NZ ASN 291.A OD1 no hydrogen 2.859 N/A GLN 4.A N MET 138.A O no hydrogen 2.823 N/A GLN 4.A NE2 PRO 139.A O no hydrogen 2.798 N/A GLU 5.A N LYS 3.A O no hydrogen 2.793 N/A LEU 8.A N GLU 5.A O no hydrogen 3.077 N/A ASN 11.A N PRO 131.A O no hydrogen 2.709 N/A LYS 12.A NZ TYR 13.A OH no hydrogen 3.327 N/A LYS 12.A NZ GLU 48.A O no hydrogen 2.837 N/A TYR 13.A N GLY 130.A O no hydrogen 3.045 N/A LYS 14.A NZ ASN 11.A O no hydrogen 2.895 N/A GLU 17.A N LYS 14.A O no hydrogen 2.977 N/A TYR 19.A N ILE 128.A O no hydrogen 2.769 N/A TYR 19.A OH GLU 46.A OE2 no hydrogen 2.540 N/A GLY 21.A N VAL 126.A O no hydrogen 2.962 N/A ARG 22.A N SER 44.A OG no hydrogen 3.293 N/A ARG 22.A NH1 GLU 125.A OE2 no hydrogen 3.491 N/A CYS 23.A N ALA 124.A O no hydrogen 2.733 N/A LEU 24.A N VAL 42.A O no hydrogen 2.711 N/A LEU 25.A N VAL 42.A O no hydrogen 3.335 N/A ASN 26.A ND2 LEU 117.A O no hydrogen 3.409 N/A ASN 26.A ND2 CYS 118.A O no hydrogen 3.277 N/A ASN 26.A ND2 LEU 120.A O no hydrogen 2.748 N/A THR 27.A N HIS 40.A O no hydrogen 2.910 N/A ARG 28.A NH1 GLU 37.A OE1 no hydrogen 3.526 N/A ILE 29.A N THR 38.A O no hydrogen 2.821 N/A GLY 31.A N ASP 189.A O no hydrogen 2.865 N/A GLN 33.A NE2 GLN 33.A O no hydrogen 3.476 N/A ALA 34.A N GLY 31.A O no hydrogen 3.176 N/A THR 38.A N THR 30.A OG1 no hydrogen 3.081 N/A TRP 39.A N VAL 96.A O no hydrogen 2.763 N/A TRP 39.A NE1 GLU 37.A OE2 no hydrogen 3.012 N/A HIS 40.A N THR 27.A O no hydrogen 2.652 N/A HIS 40.A ND1 TYR 193.A OH no hydrogen 2.669 N/A HIS 40.A NE2 ASP 85.A OD2 no hydrogen 2.835 N/A MET 41.A N LEU 94.A O no hydrogen 3.069 N/A VAL 42.A N LEU 25.A O no hydrogen 2.810 N/A PHE 43.A N VAL 92.A O no hydrogen 2.767 N/A SER 44.A N ARG 22.A O no hydrogen 2.885 N/A SER 44.A OG ARG 22.A O no hydrogen 3.551 N/A THR 45.A N LYS 90.A O no hydrogen 2.855 N/A GLY 47.A N THR 45.A OG1 no hydrogen 3.144 N/A GLU 48.A N THR 45.A O no hydrogen 2.794 N/A TYR 51.A N VAL 49.A O no hydrogen 3.001 N/A TYR 51.A OH SER 80.A OG no hydrogen 2.876 N/A TYR 51.A OH SER 81.A O no hydrogen 2.792 N/A TYR 51.A OH THR 91.A O no hydrogen 2.936 N/A ARG 52.A N GLN 55.A OE1 no hydrogen 3.107 N/A ARG 52.A NH1 GLN 4.A O no hydrogen 2.884 N/A ARG 52.A NH1 GLU 6.A O no hydrogen 2.695 N/A ARG 52.A NH2 GLU 6.A O no hydrogen 2.690 N/A GLU 53.A N GLU 53.A OE1 no hydrogen 2.655 N/A GLN 55.A N ARG 52.A O no hydrogen 3.075 N/A GLN 55.A NE2 VAL 9.A O no hydrogen 2.994 N/A GLN 55.A NE2 GLY 133.A O no hydrogen 2.922 N/A SER 56.A N VAL 132.A O no hydrogen 2.875 N/A ILE 57.A N TYR 76.A O no hydrogen 3.123 N/A GLY 58.A N THR 129.A O no hydrogen 2.911 N/A VAL 59.A N ARG 74.A O no hydrogen 2.877 N/A ILE 60.A N LYS 127.A O no hydrogen 2.927 N/A ASP 65.A N LYS 69.A O no hydrogen 2.748 N/A ASN 67.A N ASP 65.A OD2 no hydrogen 2.953 N/A GLY 68.A N ASP 65.A O no hydrogen 3.069 N/A LYS 69.A N ASP 65.A OD2 no hydrogen 2.764 N/A ARG 74.A N VAL 59.A O no hydrogen 3.061 N/A ARG 74.A NH1 LYS 72.A O no hydrogen 2.740 N/A TYR 76.A N ILE 57.A O no hydrogen 2.982 N/A ILE 78.A N GLN 55.A O no hydrogen 2.951 N/A ALA 79.A N SER 93.A O no hydrogen 2.885 N/A SER 80.A OG TYR 51.A OH no hydrogen 2.876 N/A SER 81.A OG GLU 168.A OE2 no hydrogen 2.486 N/A ALA 82.A N GLU 53.A OE2 no hydrogen 2.829 N/A GLY 84.A N SER 81.A O no hydrogen 2.943 N/A GLY 84.A N SER 81.A OG no hydrogen 3.351 N/A GLY 87.A N GLY 84.A O no hydrogen 2.863 N/A SER 89.A N LEU 83.A O no hydrogen 2.689 N/A LYS 90.A N ASP 88.A OD1 no hydrogen 2.937 N/A VAL 92.A N PHE 43.A O no hydrogen 2.949 N/A SER 93.A N SER 80.A OG no hydrogen 2.997 N/A SER 93.A OG ASP 85.A OD2 no hydrogen 2.591 N/A LEU 94.A N MET 41.A O no hydrogen 2.912 N/A VAL 96.A N TRP 39.A O no hydrogen 2.868 N/A ARG 98.A N GLU 37.A O no hydrogen 2.853 N/A ARG 98.A NE GLU 37.A OE2 no hydrogen 2.848 N/A ARG 98.A NH1 ASN 115.A OD1 no hydrogen 3.009 N/A ARG 98.A NH1 ASP 119.A OD1 no hydrogen 2.928 N/A ARG 98.A NH2 GLU 37.A OE2 no hydrogen 3.410 N/A ARG 98.A NH2 ASP 119.A OD1 no hydrogen 3.068 N/A LEU 99.A N SER 114.A OG no hydrogen 2.807 N/A TYR 101.A N VAL 109.A O no hydrogen 3.147 N/A ASN 103.A N GLU 107.A O no hydrogen 3.035 N/A ASN 103.A ND2 GLU 107.A OE1 no hydrogen 2.936 N/A GLN 105.A N ASN 103.A OD1 no hydrogen 2.804 N/A GLN 105.A NE2 ASP 104.A OD1 no hydrogen 2.748 N/A GLY 106.A N ASN 103.A O no hydrogen 3.166 N/A GLU 107.A N ASN 103.A OD1 no hydrogen 2.885 N/A VAL 109.A N TYR 101.A O no hydrogen 2.697 N/A GLY 111.A N LEU 99.A O no hydrogen 2.714 N/A CYS 113.A SG VAL 59.A O no hydrogen 3.642 N/A ASN 115.A N GLY 111.A O no hydrogen 3.418 N/A ASN 115.A ND2 LEU 99.A O no hydrogen 3.140 N/A ASN 115.A ND2 GLY 111.A O no hydrogen 2.540 N/A PHE 116.A N VAL 112.A O no hydrogen 3.230 N/A LEU 117.A N CYS 113.A O no hydrogen 2.879 N/A CYS 118.A N SER 114.A O no hydrogen 2.967 N/A CYS 118.A SG VAL 96.A O no hydrogen 3.649 N/A CYS 118.A SG SER 114.A O no hydrogen 3.308 N/A ASP 119.A N ASN 115.A O no hydrogen 2.937 N/A LEU 120.A N LEU 117.A O no hydrogen 3.127 N/A GLY 123.A N CYS 23.A O no hydrogen 2.774 N/A ALA 124.A N LYS 121.A O no hydrogen 2.957 N/A VAL 126.A N GLY 21.A O no hydrogen 2.882 N/A ILE 128.A N TYR 19.A O no hydrogen 2.758 N/A THR 129.A N GLY 58.A O no hydrogen 2.839 N/A GLY 130.A N TYR 13.A O no hydrogen 2.992 N/A VAL 132.A N SER 56.A O no hydrogen 2.640 N/A LYS 140.A N LYS 2.A O no hydrogen 2.694 N/A LYS 140.A NZ SER 1.A O no hydrogen 3.015 N/A LYS 140.A NZ LYS 3.A O no hydrogen 2.708 N/A ASN 143.A N ASP 141.A OD1 no hydrogen 2.750 N/A ALA 144.A N ASP 141.A O no hydrogen 3.189 N/A THR 145.A N ASN 247.A O no hydrogen 2.853 N/A ILE 146.A N LEU 178.A O no hydrogen 2.803 N/A ILE 147.A N TYR 249.A O no hydrogen 2.956 N/A MET 148.A N TRP 180.A O no hydrogen 2.730 N/A LEU 149.A N TYR 251.A O no hydrogen 2.818 N/A ALA 150.A N PHE 182.A O no hydrogen 2.848 N/A THR 151.A N CYS 253.A O no hydrogen 3.245 N/A GLY 152.A N GLY 184.A O no hydrogen 3.166 N/A THR 153.A OG1 TYR 295.A OH no hydrogen 2.811 N/A GLY 154.A N THR 151.A O no hydrogen 2.927 N/A ILE 155.A N GLY 152.A O no hydrogen 3.189 N/A ALA 156.A N THR 153.A O no hydrogen 2.989 N/A ARG 159.A N ILE 155.A O no hydrogen 2.959 N/A ARG 159.A N ALA 156.A O no hydrogen 3.112 N/A ARG 159.A NE GLU 196.A OE1 no hydrogen 2.682 N/A ARG 159.A NE GLU 196.A OE2 no hydrogen 3.371 N/A ARG 159.A NH1 ALA 79.A O no hydrogen 2.731 N/A ARG 159.A NH1 ASP 85.A OD1 no hydrogen 2.914 N/A ARG 159.A NH2 ASP 85.A OD1 no hydrogen 3.199 N/A ARG 159.A NH2 GLU 196.A OE2 no hydrogen 2.848 N/A SER 160.A N ALA 156.A O no hydrogen 3.132 N/A SER 160.A OG SER 80.A O no hydrogen 2.734 N/A PHE 161.A N PRO 157.A O no hydrogen 2.848 N/A LEU 162.A N PHE 158.A O no hydrogen 2.807 N/A TRP 163.A N ARG 159.A O no hydrogen 2.999 N/A TRP 163.A NE1 GLU 196.A OE1 no hydrogen 2.948 N/A LYS 164.A N SER 160.A O no hydrogen 3.448 N/A LYS 164.A NZ GLN 4.A OE1 no hydrogen 2.814 N/A MET 165.A N PHE 161.A O no hydrogen 3.019 N/A PHE 166.A N LEU 162.A O no hydrogen 2.832 N/A PHE 167.A N TRP 163.A O no hydrogen 2.901 N/A HIS 170.A NE2 GLU 168.A OE1 no hydrogen 2.754 N/A ASP 172.A N ASP 172.A OD1 no hydrogen 2.630 N/A TYR 173.A N HIS 170.A O no hydrogen 2.897 N/A LYS 174.A NZ GLU 171.A OE1 no hydrogen 3.271 N/A TYR 175.A OH ALA 144.A O no hydrogen 2.703 N/A THR 176.A N PRO 142.A O no hydrogen 2.859 N/A THR 176.A OG1 ASN 143.A OD1 no hydrogen 2.813 N/A ALA 179.A N ASN 207.A O no hydrogen 2.850 N/A TRP 180.A N ILE 146.A O no hydrogen 2.793 N/A TRP 180.A NE1 ASP 211.A OD2 no hydrogen 2.877 N/A LEU 181.A N ARG 209.A O no hydrogen 2.931 N/A PHE 182.A N MET 148.A O no hydrogen 2.806 N/A LEU 183.A N ASP 211.A O no hydrogen 2.969 N/A GLY 184.A N ALA 150.A O no hydrogen 2.808 N/A VAL 185.A N ALA 213.A O no hydrogen 2.998 N/A THR 187.A N THR 190.A OG1 no hydrogen 3.377 N/A SER 188.A N GLU 217.A OE2 no hydrogen 2.720 N/A SER 188.A OG GLU 217.A OE1 no hydrogen 2.950 N/A SER 188.A OG GLU 217.A OE2 no hydrogen 3.325 N/A THR 190.A N THR 187.A O no hydrogen 2.962 N/A THR 190.A OG1 THR 187.A O no hydrogen 2.729 N/A LEU 192.A N THR 190.A O no hydrogen 3.006 N/A TYR 193.A OH HIS 40.A ND1 no hydrogen 2.669 N/A LYS 194.A N LEU 191.A O no hydrogen 3.143 N/A LYS 194.A NZ GLU 198.A OE1 no hydrogen 3.479 N/A LEU 197.A N TYR 193.A O no hydrogen 2.882 N/A GLU 198.A N LYS 194.A O no hydrogen 2.911 N/A LYS 199.A N GLU 195.A O no hydrogen 2.981 N/A MET 200.A N GLU 196.A O no hydrogen 3.019 N/A LYS 201.A N LEU 197.A O no hydrogen 3.020 N/A LYS 201.A NZ PRO 205.A O no hydrogen 3.011 N/A LYS 201.A NZ PHE 208.A O no hydrogen 2.742 N/A GLU 202.A N GLU 198.A O no hydrogen 3.071 N/A MET 203.A N LYS 199.A O no hydrogen 3.157 N/A ALA 204.A N MET 200.A O no hydrogen 2.908 N/A ASN 207.A N ALA 204.A O no hydrogen 3.284 N/A PHE 208.A N ALA 204.A O no hydrogen 3.024 N/A ARG 209.A N ALA 179.A O no hydrogen 2.808 N/A ARG 209.A NH1 GLU 238.A OE2 no hydrogen 2.791 N/A ARG 209.A NH2 GLU 238.A OE1 no hydrogen 2.941 N/A ASP 211.A N LEU 181.A O no hydrogen 2.908 N/A ALA 213.A N LEU 183.A O no hydrogen 2.870 N/A VAL 214.A N GLN 218.A OE1 no hydrogen 2.906 N/A SER 215.A N VAL 185.A O no hydrogen 3.235 N/A ARG 216.A N PRO 186.A O no hydrogen 3.074 N/A GLU 217.A N VAL 214.A O no hydrogen 3.108 N/A GLN 218.A N VAL 214.A O no hydrogen 2.794 N/A THR 219.A OG1 ASN 220.A O no hydrogen 3.155 N/A ASN 220.A N GLU 224.A O no hydrogen 2.983 N/A ASN 220.A ND2 GLU 224.A OE2 no hydrogen 2.942 N/A GLY 223.A N ASN 220.A O no hydrogen 2.929 N/A GLU 224.A N ASN 220.A OD1 no hydrogen 2.979 N/A LYS 225.A NZ TYR 227.A OH no hydrogen 2.754 N/A MET 226.A N GLN 218.A O no hydrogen 2.892 N/A TYR 227.A N LYS 225.A O no hydrogen 3.020 N/A TYR 227.A N THR 230.A OG1 no hydrogen 3.167 N/A GLN 229.A N GLN 229.A OE1 no hydrogen 2.703 N/A THR 230.A N TYR 227.A O no hydrogen 2.995 N/A THR 230.A OG1 LYS 225.A O no hydrogen 3.061 N/A ARG 231.A N TYR 227.A O no hydrogen 3.104 N/A ARG 231.A NE PHE 212.A O no hydrogen 2.856 N/A ARG 231.A NH2 PHE 212.A O no hydrogen 3.056 N/A ARG 231.A NH2 GLN 218.A OE1 no hydrogen 2.931 N/A MET 232.A N ILE 228.A O no hydrogen 3.021 N/A ALA 233.A N GLN 229.A O no hydrogen 2.980 N/A GLU 234.A N ARG 231.A O no hydrogen 3.013 N/A TYR 235.A N MET 232.A O no hydrogen 2.799 N/A TYR 235.A OH ASP 211.A OD1 no hydrogen 2.534 N/A LYS 236.A N ALA 233.A O no hydrogen 3.353 N/A GLU 237.A N GLU 237.A OE2 no hydrogen 2.659 N/A LEU 239.A N TYR 235.A O no hydrogen 2.974 N/A TRP 240.A N LYS 236.A O no hydrogen 3.083 N/A TRP 240.A NE1 ASP 273.A OD2 no hydrogen 2.844 N/A GLU 241.A N GLU 237.A O no hydrogen 3.174 N/A LEU 242.A N GLU 238.A O no hydrogen 2.984 N/A LEU 243.A N LEU 239.A O no hydrogen 2.842 N/A LYS 244.A N GLU 241.A O no hydrogen 3.240 N/A LYS 244.A NZ ASP 273.A OD2 no hydrogen 3.172 N/A LYS 245.A N LEU 242.A O no hydrogen 3.003 N/A ASN 247.A ND2 ASN 143.A O no hydrogen 3.607 N/A THR 248.A N LYS 245.A O no hydrogen 3.332 N/A THR 248.A OG1 LEU 242.A O no hydrogen 2.692 N/A TYR 249.A N THR 145.A O no hydrogen 2.860 N/A VAL 250.A N GLN 289.A O no hydrogen 2.772 N/A TYR 251.A N ILE 147.A O no hydrogen 2.874 N/A TYR 251.A OH LEU 137.A O no hydrogen 2.641 N/A MET 252.A N ASN 291.A O no hydrogen 2.754 N/A CYS 253.A N LEU 149.A O no hydrogen 2.965 N/A CYS 253.A SG GLU 293.A O no hydrogen 3.366 N/A GLY 254.A N GLU 293.A O no hydrogen 3.348 N/A LEU 255.A N THR 151.A OG1 no hydrogen 2.983 N/A LYS 256.A N TYR 295.A O no hydrogen 2.682 N/A MET 258.A N LEU 255.A O no hydrogen 3.113 N/A LYS 260.A NZ ASP 264.A OD2 no hydrogen 3.011 N/A ILE 262.A N MET 258.A O no hydrogen 3.456 N/A ASP 263.A N GLU 259.A O no hydrogen 2.886 N/A ASP 264.A N LYS 260.A O no hydrogen 2.891 N/A ILE 265.A N GLY 261.A O no hydrogen 3.352 N/A MET 266.A N ILE 262.A O no hydrogen 3.172 N/A LEU 267.A N ASP 263.A O no hydrogen 2.656 N/A ASP 268.A N ASP 264.A O no hydrogen 3.305 N/A LEU 269.A N ILE 265.A O no hydrogen 3.139 N/A ALA 270.A N MET 266.A O no hydrogen 2.907 N/A ALA 271.A N LEU 267.A O no hydrogen 3.016 N/A LYS 272.A N ASP 268.A O no hydrogen 3.057 N/A ASP 273.A N ALA 270.A O no hydrogen 2.766 N/A GLY 274.A N ALA 271.A O no hydrogen 2.706 N/A ILE 275.A N ALA 270.A O no hydrogen 2.862 N/A TRP 277.A NE1 ASP 263.A OD1 no hydrogen 2.777 N/A LEU 278.A N ASN 276.A OD1 no hydrogen 2.958 N/A ASP 279.A N ASN 276.A O no hydrogen 3.164 N/A TYR 280.A N ASN 276.A O no hydrogen 3.090 N/A TYR 280.A OH LEU 243.A O no hydrogen 3.021 N/A LYS 281.A N TRP 277.A O no hydrogen 2.806 N/A LYS 281.A NZ ASP 263.A OD1 no hydrogen 2.990 N/A LYS 281.A NZ ASP 263.A OD2 no hydrogen 2.773 N/A LYS 282.A N LEU 278.A O no hydrogen 3.381 N/A GLN 283.A N ASP 279.A O no hydrogen 3.099 N/A GLN 283.A NE2 ASP 279.A OD2 no hydrogen 2.930 N/A LEU 284.A N TYR 280.A O no hydrogen 2.880 N/A LYS 285.A N LYS 281.A O no hydrogen 2.911 N/A LYS 286.A N LYS 282.A O no hydrogen 3.051 N/A SER 287.A N GLN 283.A O no hydrogen 2.849 N/A SER 287.A OG GLN 283.A O no hydrogen 3.198 N/A SER 287.A OG LEU 284.A O no hydrogen 3.278 N/A GLU 288.A N LYS 285.A O no hydrogen 3.041 N/A GLN 289.A N LEU 284.A O no hydrogen 2.659 N/A GLN 289.A NE2 SER 287.A OG no hydrogen 2.636 N/A ASN 291.A N VAL 250.A O no hydrogen 2.712 N/A ASN 291.A ND2 VAL 250.A O no hydrogen 3.332 N/A ASN 291.A ND2 GLU 288.A O no hydrogen 3.319 N/A VAL 292.A N GLU 135.A OE2 no hydrogen 3.071 N/A GLU 293.A N MET 252.A O no hydrogen 2.792 N/A TYR 295.A N GLY 254.A O no hydrogen 2.890 N/A TYR 295.A OH THR 153.A OG1 no hydrogen 2.811 N/A