Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3vv7_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PHE 3.A N ASP 172.A OD2 no hydrogen 2.938 N/A GLU 5.A N GLU 5.A OE1 no hydrogen 2.594 N/A MET 6.A N PHE 3.A O no hydrogen 2.912 N/A VAL 7.A N VAL 4.A O no hydrogen 3.314 N/A ASP 8.A N SER 165.A OG no hydrogen 2.816 N/A ASN 9.A N MET 6.A O no hydrogen 3.261 N/A ASN 9.A ND2 HIS 93.A O no hydrogen 2.981 N/A ASN 9.A ND2 MET 166.A O no hydrogen 2.997 N/A LEU 10.A N GLY 164.A O no hydrogen 2.958 N/A ARG 11.A N TYR 19.A O no hydrogen 3.057 N/A ARG 11.A NH1 ASP 8.A OD2 no hydrogen 2.689 N/A ARG 11.A NH2 ASP 8.A OD1 no hydrogen 2.977 N/A ARG 11.A NH2 ASP 8.A OD2 no hydrogen 3.479 N/A ARG 11.A NH2 LEU 10.A O no hydrogen 2.889 N/A GLN 16.A N LYS 13.A O no hydrogen 2.946 N/A TYR 18.A OH GLU 315.A OE2 no hydrogen 2.579 N/A TYR 19.A N ARG 11.A O no hydrogen 2.731 N/A VAL 20.A N ILE 33.A O no hydrogen 2.746 N/A MET 22.A N LEU 31.A O no hydrogen 2.875 N/A THR 23.A N SER 90.A O no hydrogen 2.876 N/A THR 23.A OG1 SER 90.A OG no hydrogen 2.687 N/A VAL 24.A N GLN 29.A O no hydrogen 2.832 N/A GLY 25.A N LEU 88.A O no hydrogen 2.819 N/A SER 26.A N SER 61.A OG no hydrogen 3.142 N/A SER 26.A OG THR 63.A OG1 no hydrogen 2.678 N/A GLN 29.A N VAL 24.A O no hydrogen 2.721 N/A GLN 29.A NE2 GLN 57.A O no hydrogen 3.041 N/A LEU 31.A N MET 22.A O no hydrogen 2.918 N/A ASN 32.A N GLU 120.A OE1 no hydrogen 2.835 N/A ASN 32.A ND2 ASN 118.A O no hydrogen 2.901 N/A ILE 33.A N VAL 20.A O no hydrogen 2.774 N/A LEU 34.A N GLY 121.A O no hydrogen 2.875 N/A VAL 35.A N TYR 18.A O no hydrogen 2.816 N/A ASP 36.A N LEU 123.A O no hydrogen 2.965 N/A THR 37.A N SER 221.A OG no hydrogen 2.884 N/A THR 37.A OG1 VAL 219.A O no hydrogen 2.971 N/A GLY 38.A N ASP 36.A OD1 no hydrogen 2.938 N/A SER 39.A OG ASP 36.A OD2 no hydrogen 2.573 N/A SER 40.A OG TYR 127.A O no hydrogen 2.685 N/A ALA 43.A N ILE 122.A O no hydrogen 3.010 N/A VAL 44.A N ALA 104.A O no hydrogen 2.946 N/A GLY 45.A N GLU 120.A O no hydrogen 2.789 N/A ALA 46.A N ILE 106.A O no hydrogen 3.105 N/A HIS 49.A N ALA 47.A O no hydrogen 2.871 N/A PHE 51.A N HIS 49.A ND1 no hydrogen 3.084 N/A LEU 52.A N HIS 49.A O no hydrogen 3.021 N/A ARG 54.A NE GLU 120.A OE1 no hydrogen 2.960 N/A TYR 56.A N GLY 45.A O no hydrogen 2.832 N/A TYR 56.A OH ASP 87.A OD2 no hydrogen 2.536 N/A GLN 57.A N GLN 29.A OE1 no hydrogen 2.822 N/A ARG 58.A NH1 GLU 83.A OE1 no hydrogen 2.794 N/A ARG 58.A NH2 GLU 83.A OE1 no hydrogen 3.232 N/A LEU 60.A N GLN 57.A O no hydrogen 2.969 N/A SER 61.A N ARG 58.A O no hydrogen 2.967 N/A SER 61.A OG THR 63.A OG1 no hydrogen 3.428 N/A SER 61.A OG ASP 87.A OD1 no hydrogen 3.234 N/A SER 61.A OG ASP 87.A OD2 no hydrogen 2.692 N/A SER 62.A N SER 26.A O no hydrogen 2.978 N/A SER 62.A OG SER 26.A O no hydrogen 3.336 N/A THR 63.A OG1 SER 26.A OG no hydrogen 2.678 N/A THR 63.A OG1 SER 61.A OG no hydrogen 3.428 N/A THR 63.A OG1 ASP 87.A OD1 no hydrogen 2.683 N/A TYR 64.A N SER 61.A O no hydrogen 3.447 N/A ARG 65.A N THR 86.A O no hydrogen 2.894 N/A LEU 67.A N LEU 84.A O no hydrogen 3.063 N/A ARG 68.A N ASP 66.A OD1 no hydrogen 2.755 N/A VAL 71.A N GLY 82.A O no hydrogen 2.879 N/A VAL 73.A N TRP 80.A O no hydrogen 2.751 N/A TYR 75.A N GLY 78.A O no hydrogen 2.673 N/A LYS 79.A N ASP 110.A O no hydrogen 2.949 N/A LYS 79.A NZ GLU 81.A OE1 no hydrogen 3.043 N/A TRP 80.A N VAL 73.A O no hydrogen 3.008 N/A GLU 81.A N GLU 108.A O no hydrogen 2.835 N/A GLY 82.A N VAL 71.A O no hydrogen 2.842 N/A GLU 83.A N ALA 105.A O no hydrogen 2.859 N/A LEU 84.A N LYS 69.A O no hydrogen 2.868 N/A GLY 85.A N ILE 103.A O no hydrogen 3.054 N/A THR 86.A N ARG 65.A O no hydrogen 2.741 N/A ASP 87.A N ALA 101.A O no hydrogen 3.239 N/A LEU 88.A N ASP 87.A OD1 no hydrogen 2.754 N/A VAL 89.A N VAL 99.A O no hydrogen 2.728 N/A SER 90.A N THR 23.A O no hydrogen 3.140 N/A SER 90.A OG THR 23.A OG1 no hydrogen 2.687 N/A GLY 94.A N ILE 91.A O no hydrogen 2.779 N/A VAL 97.A N PRO 95.A O no hydrogen 2.875 N/A VAL 99.A N VAL 89.A O no hydrogen 2.890 N/A ARG 100.A NH1 THR 63.A O no hydrogen 3.005 N/A ARG 100.A NH1 THR 86.A OG1 no hydrogen 2.828 N/A ARG 100.A NH2 THR 63.A O no hydrogen 2.885 N/A ALA 101.A N ASP 87.A O no hydrogen 3.051 N/A ILE 103.A N GLY 85.A O no hydrogen 2.894 N/A ALA 104.A N PHE 42.A O no hydrogen 2.911 N/A ALA 105.A N GLU 83.A O no hydrogen 2.861 N/A ILE 106.A N VAL 44.A O no hydrogen 2.711 N/A THR 107.A N GLU 81.A O no hydrogen 3.022 N/A GLU 108.A N GLU 81.A O no hydrogen 3.329 N/A ASP 110.A N LYS 79.A O no hydrogen 2.850 N/A LYS 111.A NZ ASP 110.A OD1 no hydrogen 3.507 N/A LYS 111.A NZ ASP 110.A OD2 no hydrogen 2.897 N/A SER 117.A N ILE 114.A O no hydrogen 3.019 N/A SER 117.A OG ILE 114.A O no hydrogen 3.105 N/A ASN 118.A ND2 TYR 19.A OH no hydrogen 3.144 N/A GLU 120.A N ASN 32.A O no hydrogen 2.783 N/A ILE 122.A N ALA 43.A O no hydrogen 2.770 N/A LEU 123.A N LEU 34.A O no hydrogen 2.690 N/A GLY 124.A N ASN 41.A O no hydrogen 2.893 N/A LEU 125.A N ASP 36.A O no hydrogen 2.897 N/A ALA 126.A N SER 39.A O no hydrogen 2.857 N/A TYR 127.A N TRP 189.A O no hydrogen 3.085 N/A ILE 130.A N TYR 127.A O no hydrogen 3.218 N/A ALA 131.A N ALA 128.A O no hydrogen 2.854 N/A SER 136.A N ASP 134.A OD1 no hydrogen 2.949 N/A SER 136.A OG ASP 134.A OD1 no hydrogen 2.560 N/A LEU 137.A N ASP 134.A O no hydrogen 3.204 N/A SER 143.A N PRO 139.A O no hydrogen 3.058 N/A SER 143.A OG GLU 138.A OE2 no hydrogen 2.500 N/A SER 143.A OG PRO 139.A O no hydrogen 3.378 N/A LEU 144.A N PHE 140.A O no hydrogen 2.866 N/A VAL 145.A N PHE 141.A O no hydrogen 3.007 N/A LYS 146.A N ASP 142.A O no hydrogen 3.058 N/A GLN 147.A N SER 143.A O no hydrogen 2.906 N/A THR 148.A N LEU 144.A O no hydrogen 3.128 N/A THR 148.A OG1 LEU 144.A O no hydrogen 2.630 N/A VAL 150.A N THR 148.A OG1 no hydrogen 3.114 N/A LEU 153.A N PRO 151.A O no hydrogen 2.833 N/A PHE 154.A N PHE 321.A O no hydrogen 3.397 N/A SER 155.A N ILE 167.A O no hydrogen 2.921 N/A SER 155.A OG GLY 170.A O no hydrogen 3.017 N/A SER 155.A OG TYR 318.A OH no hydrogen 2.567 N/A LEU 156.A N VAL 319.A O no hydrogen 2.775 N/A GLN 157.A N SER 165.A O no hydrogen 2.898 N/A CYS 159.A N GLY 163.A O no hydrogen 2.843 N/A GLY 160.A N TYR 18.A OH no hydrogen 2.835 N/A VAL 162.A N GLY 12.A O no hydrogen 3.033 N/A GLY 163.A N GLY 160.A O no hydrogen 3.305 N/A GLY 164.A N LEU 10.A O no hydrogen 3.205 N/A SER 165.A N GLN 157.A O no hydrogen 2.793 N/A MET 166.A N ASN 9.A OD1 no hydrogen 2.785 N/A ILE 167.A N SER 155.A O no hydrogen 2.838 N/A GLY 169.A N LEU 153.A O no hydrogen 2.773 N/A ASP 172.A N TYR 318.A OH no hydrogen 2.913 N/A HIS 173.A N GLY 1.A O no hydrogen 3.044 N/A HIS 173.A ND1 TYR 176.A OH no hydrogen 2.657 N/A SER 174.A N ASP 172.A OD1 no hydrogen 3.024 N/A SER 174.A OG ASP 172.A OD1 no hydrogen 2.426 N/A LEU 175.A N ASP 172.A O no hydrogen 2.943 N/A TYR 176.A OH HIS 173.A ND1 no hydrogen 2.657 N/A THR 177.A N VAL 332.A O no hydrogen 3.090 N/A SER 179.A OG LEU 180.A O no hydrogen 2.987 N/A TRP 181.A N PHE 330.A O no hydrogen 2.874 N/A THR 183.A N ILE 328.A O no hydrogen 2.948 N/A THR 183.A OG1 MET 272.A O no hydrogen 2.578 N/A ILE 185.A N LYS 326.A O no hydrogen 2.901 N/A ARG 186.A N GLU 192.A O no hydrogen 2.737 N/A ARG 186.A NH1 GLU 192.A OE2 no hydrogen 3.210 N/A ARG 186.A NH1 TYR 360.A O no hydrogen 2.872 N/A ARG 186.A NH2 TYR 360.A O no hydrogen 3.173 N/A ARG 187.A NH1 GLU 129.A OE2 no hydrogen 2.416 N/A TRP 189.A N ARG 187.A O no hydrogen 3.121 N/A TRP 189.A N TYR 190.A O no hydrogen 3.113 N/A TRP 189.A NE1 GLU 192.A OE1 no hydrogen 2.957 N/A TYR 191.A OH LEU 125.A O no hydrogen 2.619 N/A VAL 193.A N SER 217.A O no hydrogen 2.910 N/A VAL 196.A N TYR 270.A O no hydrogen 2.890 N/A ARG 197.A NE GLU 199.A OE2 no hydrogen 3.070 N/A ARG 197.A NH2 GLU 199.A OE2 no hydrogen 3.265 N/A GLU 199.A N SER 268.A O no hydrogen 2.942 N/A ILE 200.A N GLN 203.A O no hydrogen 2.869 N/A ASN 201.A N VAL 266.A O no hydrogen 2.911 N/A GLN 203.A N ILE 200.A O no hydrogen 2.801 N/A LEU 205.A N VAL 198.A O no hydrogen 3.029 N/A LYS 206.A N ASP 204.A OD1 no hydrogen 3.193 N/A LYS 210.A N ASP 208.A OD1 no hydrogen 3.300 N/A LYS 210.A NZ ASP 357.A O no hydrogen 3.260 N/A GLU 211.A N ASP 208.A O no hydrogen 2.821 N/A TYR 212.A N CYS 209.A O no hydrogen 2.887 N/A ASN 213.A N LYS 210.A O no hydrogen 3.343 N/A ASN 213.A ND2 SER 217.A OG no hydrogen 2.658 N/A TYR 214.A N GLU 211.A O no hydrogen 3.221 N/A LYS 216.A NZ THR 305.A O no hydrogen 2.821 N/A ILE 218.A N THR 307.A O no hydrogen 3.030 N/A VAL 219.A N TYR 191.A O no hydrogen 3.044 N/A ASP 220.A N MET 309.A O no hydrogen 2.959 N/A SER 221.A N THR 37.A OG1 no hydrogen 2.927 N/A SER 221.A OG VAL 35.A O no hydrogen 2.658 N/A GLY 222.A N ASP 220.A OD1 no hydrogen 2.771 N/A THR 223.A N ASP 220.A O no hydrogen 3.188 N/A THR 223.A OG1 ASP 220.A OD2 no hydrogen 2.673 N/A THR 224.A OG1 GLY 15.A O no hydrogen 3.219 N/A ASN 225.A ND2 SER 301.A OG no hydrogen 2.986 N/A LEU 226.A N ALA 299.A O no hydrogen 3.017 N/A ARG 227.A N VAL 308.A O no hydrogen 2.948 N/A ARG 227.A NH2 GLN 302.A O no hydrogen 3.124 N/A LEU 228.A N SER 301.A O no hydrogen 2.857 N/A PHE 233.A N PRO 229.A O no hydrogen 2.749 N/A GLU 234.A N LYS 230.A O no hydrogen 2.694 N/A ALA 235.A N LYS 231.A O no hydrogen 3.389 N/A ALA 236.A N VAL 232.A O no hydrogen 2.829 N/A VAL 237.A N PHE 233.A O no hydrogen 2.778 N/A LYS 238.A N GLU 234.A O no hydrogen 2.907 N/A SER 239.A N ALA 235.A O no hydrogen 2.970 N/A ILE 240.A N ALA 236.A O no hydrogen 2.687 N/A LYS 241.A N VAL 237.A O no hydrogen 2.450 N/A ALA 242.A N LYS 238.A O no hydrogen 3.010 N/A ALA 243.A N SER 239.A O no hydrogen 2.958 N/A SER 244.A OG ILE 240.A O no hydrogen 2.559 N/A SER 245.A N ALA 242.A O no hydrogen 3.066 N/A SER 245.A OG LYS 241.A O no hydrogen 2.984 N/A SER 245.A OG ALA 242.A O no hydrogen 3.141 N/A PHE 252.A N PRO 249.A O no hydrogen 3.357 N/A LEU 254.A N GLY 251.A O no hydrogen 3.014 N/A GLY 255.A N PHE 252.A O no hydrogen 2.967 N/A GLU 256.A N GLY 251.A O no hydrogen 2.965 N/A VAL 259.A N TYR 296.A O no hydrogen 3.285 N/A PHE 264.A N TRP 261.A O no hydrogen 2.915 N/A VAL 266.A N ASN 201.A OD1 no hydrogen 2.846 N/A ILE 267.A N ILE 284.A O no hydrogen 3.099 N/A SER 268.A N GLU 199.A O no hydrogen 2.946 N/A SER 268.A OG THR 283.A OG1 no hydrogen 2.565 N/A LEU 269.A N ILE 282.A O no hydrogen 2.907 N/A TYR 270.A N ARG 197.A O no hydrogen 2.817 N/A TYR 270.A OH GLU 199.A OE2 no hydrogen 2.605 N/A LEU 271.A N PHE 280.A O no hydrogen 2.805 N/A MET 272.A N ILE 194.A O no hydrogen 3.051 N/A VAL 275.A N GLN 278.A OE1 no hydrogen 3.172 N/A GLN 278.A N VAL 275.A O no hydrogen 3.001 N/A SER 279.A N PHE 350.A O no hydrogen 2.863 N/A SER 279.A OG THR 352.A OG1 no hydrogen 2.705 N/A PHE 280.A N LEU 271.A O no hydrogen 3.262 N/A ARG 281.A N GLU 347.A O no hydrogen 2.764 N/A ARG 281.A NE GLU 347.A OE1 no hydrogen 3.000 N/A ARG 281.A NH1 TYR 270.A OH no hydrogen 3.092 N/A ARG 281.A NH2 GLU 347.A OE1 no hydrogen 3.011 N/A ARG 281.A NH2 GLU 347.A OE2 no hydrogen 2.996 N/A ILE 282.A N LEU 269.A O no hydrogen 2.858 N/A THR 283.A N ALA 345.A O no hydrogen 2.798 N/A THR 283.A OG1 SER 268.A OG no hydrogen 2.565 N/A ILE 284.A N ILE 267.A O no hydrogen 2.926 N/A LEU 285.A N GLN 288.A OE1 no hydrogen 2.778 N/A GLN 288.A N LEU 285.A O no hydrogen 2.974 N/A GLN 288.A NE2 VAL 337.A O no hydrogen 3.167 N/A TYR 289.A N LEU 285.A O no hydrogen 3.251 N/A TYR 289.A OH PRO 265.A O no hydrogen 2.566 N/A LEU 290.A N PRO 286.A O no hydrogen 2.529 N/A ARG 291.A N LYS 297.A O no hydrogen 3.427 N/A VAL 293.A N CYS 295.A O no hydrogen 2.610 N/A TYR 296.A N VAL 259.A O no hydrogen 2.935 N/A LYS 297.A N ARG 291.A O no hydrogen 3.090 N/A ALA 299.A N TYR 289.A O no hydrogen 2.976 N/A SER 301.A N LEU 226.A O no hydrogen 3.024 N/A SER 303.A OG GLY 306.A O no hydrogen 2.874 N/A THR 305.A N SER 303.A OG no hydrogen 2.854 N/A THR 307.A N LYS 216.A O no hydrogen 2.694 N/A THR 307.A OG1 TYR 212.A O no hydrogen 2.742 N/A VAL 308.A N ARG 227.A O no hydrogen 2.731 N/A MET 309.A N ILE 218.A O no hydrogen 2.841 N/A GLY 310.A N ASN 225.A O no hydrogen 3.175 N/A ALA 311.A N THR 223.A O no hydrogen 2.771 N/A VAL 312.A N THR 224.A O no hydrogen 3.016 N/A ILE 313.A N GLY 310.A O no hydrogen 2.966 N/A MET 314.A N GLY 310.A O no hydrogen 3.062 N/A GLU 315.A N ALA 311.A O no hydrogen 2.787 N/A GLY 316.A N ILE 313.A O no hydrogen 2.934 N/A PHE 317.A N MET 314.A O no hydrogen 3.099 N/A TYR 318.A N ALA 331.A O no hydrogen 2.779 N/A VAL 319.A N LEU 156.A O no hydrogen 2.963 N/A VAL 320.A N GLY 329.A O no hydrogen 2.767 N/A PHE 321.A N PHE 154.A O no hydrogen 2.781 N/A ASP 322.A N ARG 327.A O no hydrogen 2.853 N/A ARG 323.A N PHE 321.A O no hydrogen 2.902 N/A ARG 323.A NE ASN 152.A OD1 no hydrogen 2.869 N/A ARG 323.A NH1 ASP 142.A OD1 no hydrogen 3.054 N/A ARG 323.A NH2 TYR 191.A OH no hydrogen 3.005 N/A ALA 324.A N ASN 152.A O no hydrogen 2.975 N/A ARG 325.A N ASP 322.A O no hydrogen 3.113 N/A ARG 325.A N ASP 322.A OD1 no hydrogen 3.237 N/A LYS 326.A N ARG 323.A O no hydrogen 3.173 N/A ARG 327.A N ASP 322.A O no hydrogen 3.162 N/A ARG 327.A NE ASP 322.A OD2 no hydrogen 2.867 N/A ARG 327.A NH1 GLU 274.A OE1 no hydrogen 2.800 N/A ARG 327.A NH2 ASP 322.A OD2 no hydrogen 3.230 N/A ILE 328.A N THR 183.A O no hydrogen 2.859 N/A GLY 329.A N VAL 320.A O no hydrogen 2.794 N/A PHE 330.A N TRP 181.A O no hydrogen 2.811 N/A ALA 331.A N TYR 318.A O no hydrogen 3.064 N/A SER 333.A N GLY 316.A O no hydrogen 3.217 N/A SER 333.A OG GLN 157.A OE1 no hydrogen 3.511 N/A ALA 334.A N LEU 175.A O no hydrogen 2.878 N/A CYS 335.A N SER 333.A OG no hydrogen 3.077 N/A CYS 335.A SG LEU 158.A O no hydrogen 3.995 N/A CYS 335.A SG SER 333.A OG no hydrogen 3.269 N/A HIS 336.A N SER 333.A O no hydrogen 3.471 N/A HIS 336.A ND1 SER 333.A O no hydrogen 2.965 N/A HIS 338.A ND1 HIS 336.A O no hydrogen 3.173 N/A PHE 341.A N ASP 339.A OD1 no hydrogen 2.706 N/A ARG 342.A N ASP 339.A OD1 no hydrogen 2.766 N/A ARG 342.A NH1 PHE 264.A O no hydrogen 2.770 N/A ARG 342.A NH2 TRP 261.A O no hydrogen 2.947 N/A ARG 342.A NH2 PHE 264.A O no hydrogen 2.938 N/A ALA 344.A N HIS 336.A NE2 no hydrogen 3.138 N/A ALA 345.A N THR 283.A O no hydrogen 3.053 N/A GLU 347.A N ARG 281.A O no hydrogen 2.889 N/A PHE 350.A N SER 279.A O no hydrogen 2.786 N/A THR 352.A N ASN 277.A O no hydrogen 3.063 N/A THR 352.A OG1 SER 279.A OG no hydrogen 2.705 N/A ASP 357.A N ASP 354.A O no hydrogen 3.161 N/A CYS 358.A N MET 355.A O no hydrogen 2.978 N/A CYS 358.A SG ASP 354.A O no hydrogen 3.912 N/A GLY 359.A N GLU 356.A O no hydrogen 3.220 N/A