Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3wlx_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 2.A N ASN 298.A O no hydrogen 3.049 N/A LEU 4.A N LEU 300.A O no hydrogen 2.968 N/A ARG 5.A N ASP 3.A OD1 no hydrogen 2.992 N/A ARG 5.A NE ASP 3.A OD1 no hydrogen 2.896 N/A ARG 5.A NE ASP 3.A OD2 no hydrogen 3.097 N/A ARG 5.A NH2 ASP 3.A OD2 no hydrogen 2.624 N/A SER 6.A OG ASP 7.A OD1 no hydrogen 3.089 N/A SER 6.A OG THR 8.A OG1 no hydrogen 3.243 N/A THR 8.A N SER 6.A OG no hydrogen 3.098 N/A THR 8.A OG1 SER 6.A OG no hydrogen 3.243 N/A THR 10.A N ASP 7.A O no hydrogen 3.471 N/A THR 10.A OG1 ASP 7.A O no hydrogen 3.115 N/A THR 10.A OG1 LYS 197.A O no hydrogen 2.865 N/A ARG 11.A N ASP 314.A OD2 no hydrogen 2.749 N/A MET 16.A N SER 13.A OG no hydrogen 3.296 N/A LEU 17.A N SER 13.A O no hydrogen 2.841 N/A GLU 18.A N ARG 14.A O no hydrogen 2.812 N/A ALA 19.A N ALA 15.A O no hydrogen 3.063 N/A MET 20.A N MET 16.A O no hydrogen 2.934 N/A MET 21.A N LEU 17.A O no hydrogen 3.044 N/A ASP 28.A N ARG 229.A O no hydrogen 2.782 N/A VAL 29.A N ASP 27.A OD1 no hydrogen 3.083 N/A GLY 31.A N ASP 28.A O no hydrogen 2.811 N/A ASP 32.A N ASP 27.A O no hydrogen 2.747 N/A THR 35.A N ASP 33.A OD1 no hydrogen 3.047 N/A THR 35.A OG1 PRO 24.A O no hydrogen 2.391 N/A VAL 36.A N ASP 33.A OD1 no hydrogen 3.126 N/A ASN 37.A N ASP 33.A O no hydrogen 3.117 N/A ASN 37.A ND2 GLY 31.A O no hydrogen 3.304 N/A ALA 38.A N PRO 34.A O no hydrogen 2.984 N/A LEU 39.A N THR 35.A O no hydrogen 3.025 N/A GLN 40.A N VAL 36.A O no hydrogen 3.052 N/A ASP 41.A N ASN 37.A O no hydrogen 2.809 N/A TYR 42.A N ALA 38.A O no hydrogen 2.859 N/A ALA 43.A N LEU 39.A O no hydrogen 2.934 N/A ALA 44.A N GLN 40.A O no hydrogen 3.064 N/A GLU 45.A N ASP 41.A O no hydrogen 3.053 N/A LEU 46.A N TYR 42.A O no hydrogen 2.926 N/A SER 47.A N ALA 43.A O no hydrogen 3.249 N/A SER 47.A N ALA 44.A O no hydrogen 3.271 N/A SER 47.A OG ALA 43.A O no hydrogen 2.741 N/A SER 47.A OG ALA 44.A O no hydrogen 3.155 N/A GLY 48.A N GLU 45.A O no hydrogen 3.224 N/A LYS 49.A N ALA 44.A O no hydrogen 2.872 N/A LYS 49.A NZ CYS 188.A O no hydrogen 3.048 N/A ALA 51.A N GLY 209.A O no hydrogen 3.131 N/A ILE 53.A N LEU 207.A O no hydrogen 2.843 N/A PHE 54.A N GLN 40.A OE1 no hydrogen 2.889 N/A LEU 55.A N SER 205.A O no hydrogen 2.831 N/A GLN 60.A N THR 57.A OG1 no hydrogen 3.136 N/A ALA 61.A N THR 57.A O no hydrogen 3.149 N/A ASN 62.A N GLY 58.A O no hydrogen 3.038 N/A ASN 62.A ND2 GLY 58.A O no hydrogen 2.947 N/A LEU 63.A N THR 59.A O no hydrogen 2.959 N/A VAL 64.A N GLN 60.A O no hydrogen 2.723 N/A ALA 65.A N ALA 61.A O no hydrogen 3.072 N/A LEU 66.A N ASN 62.A O no hydrogen 2.789 N/A LEU 67.A N LEU 63.A O no hydrogen 3.022 N/A SER 68.A N VAL 64.A O no hydrogen 2.906 N/A SER 68.A OG VAL 64.A O no hydrogen 2.732 N/A HIS 69.A N ALA 65.A O no hydrogen 3.125 N/A HIS 69.A NE2 SER 190.A OG no hydrogen 2.688 N/A CYS 70.A N LEU 66.A O no hydrogen 2.796 N/A GLU 71.A N GLU 74.A OE1 no hydrogen 2.608 N/A GLY 73.A N SER 97.A O no hydrogen 3.191 N/A GLU 74.A N GLU 71.A O no hydrogen 3.007 N/A GLU 75.A N ARG 129.A O no hydrogen 2.667 N/A TYR 76.A N GLN 99.A O no hydrogen 3.063 N/A TYR 76.A OH ASN 84.A O no hydrogen 2.841 N/A ILE 77.A N LEU 132.A O no hydrogen 2.762 N/A VAL 78.A N GLN 101.A O no hydrogen 3.032 N/A GLN 80.A N ILE 103.A O no hydrogen 2.852 N/A ALA 82.A N GLY 79.A O no hydrogen 3.050 N/A HIS 83.A N GLU 136.A OE1 no hydrogen 2.717 N/A HIS 83.A ND1 GLU 88.A OE2 no hydrogen 2.983 N/A ASN 84.A ND2 ASN 62.A OD1 no hydrogen 3.375 N/A ASN 84.A ND2 SER 134.A OG no hydrogen 2.885 N/A TYR 85.A N ALA 82.A O no hydrogen 3.369 N/A LEU 86.A N ALA 82.A O no hydrogen 2.897 N/A PHE 87.A N HIS 83.A O no hydrogen 2.872 N/A GLY 91.A N GLU 88.A O no hydrogen 3.007 N/A ALA 93.A N GLY 90.A O no hydrogen 3.031 N/A VAL 94.A N GLY 90.A O no hydrogen 2.805 N/A LEU 95.A N GLY 91.A O no hydrogen 2.823 N/A GLY 96.A N GLY 91.A O no hydrogen 3.209 N/A ILE 98.A N ALA 92.A O no hydrogen 2.906 N/A GLN 99.A N GLU 74.A O no hydrogen 3.024 N/A GLN 101.A N TYR 76.A O no hydrogen 2.967 N/A GLN 101.A NE2 PRO 102.A O no hydrogen 3.225 N/A ILE 103.A N VAL 78.A O no hydrogen 2.779 N/A ALA 106.A N THR 110.A O no hydrogen 2.471 N/A GLY 109.A N ALA 106.A O no hydrogen 2.851 N/A THR 110.A N ASP 108.A OD2 no hydrogen 3.001 N/A LYS 115.A N PRO 112.A O no hydrogen 3.008 N/A LYS 115.A NZ ASP 104.A O no hydrogen 2.513 N/A VAL 116.A N PRO 112.A O no hydrogen 3.037 N/A ALA 117.A N LEU 113.A O no hydrogen 2.965 N/A LYS 119.A N VAL 116.A O no hydrogen 2.917 N/A ILE 120.A N ALA 117.A O no hydrogen 3.346 N/A LYS 121.A N THR 130.A OG1 no hydrogen 2.956 N/A LYS 121.A NZ GLU 75.A OE1 no hydrogen 3.141 N/A LYS 121.A NZ GLU 75.A OE2 no hydrogen 2.821 N/A LYS 121.A NZ GLN 101.A OE1 no hydrogen 3.088 N/A LYS 121.A NZ LYS 119.A O no hydrogen 2.372 N/A ASP 124.A N PRO 122.A O no hydrogen 2.764 N/A HIS 126.A N ASP 124.A OD2 no hydrogen 2.908 N/A HIS 126.A ND1 ASP 124.A OD2 no hydrogen 2.577 N/A PHE 127.A N ASP 124.A O no hydrogen 3.040 N/A ARG 129.A N GLY 73.A O no hydrogen 3.184 N/A THR 130.A OG1 GLU 75.A OE2 no hydrogen 2.790 N/A LYS 131.A N GLU 75.A O no hydrogen 2.854 N/A LYS 131.A NZ HIS 69.A O no hydrogen 2.854 N/A LYS 131.A NZ GLU 74.A OE1 no hydrogen 3.103 N/A LEU 132.A N GLU 75.A O no hydrogen 3.273 N/A LEU 133.A N ALA 162.A O no hydrogen 2.815 N/A SER 134.A N ILE 77.A O no hydrogen 2.866 N/A LEU 135.A N HIS 164.A O no hydrogen 2.648 N/A ASN 137.A N ASP 166.A O no hydrogen 3.027 N/A ASN 137.A ND2 TYR 177.A OH no hydrogen 3.133 N/A THR 138.A N ARG 169.A O no hydrogen 3.412 N/A HIS 139.A N LYS 142.A O no hydrogen 3.047 N/A HIS 139.A ND1 GLU 136.A OE2 no hydrogen 2.762 N/A LYS 142.A N HIS 139.A O no hydrogen 3.043 N/A LYS 142.A NZ ALA 107.A O no hydrogen 2.467 N/A LEU 144.A N ASN 137.A OD1 no hydrogen 3.224 N/A TYR 148.A N PRO 145.A O no hydrogen 3.081 N/A TYR 148.A OH LEU 111.A O no hydrogen 2.510 N/A LEU 149.A N PRO 145.A O no hydrogen 3.384 N/A LYS 150.A N ARG 146.A O no hydrogen 3.317 N/A GLU 151.A N GLU 147.A O no hydrogen 3.139 N/A ALA 152.A N TYR 148.A O no hydrogen 2.685 N/A TRP 153.A N LEU 149.A O no hydrogen 3.197 N/A GLU 154.A N LYS 150.A O no hydrogen 2.957 N/A PHE 155.A N GLU 151.A O no hydrogen 3.016 N/A THR 156.A N ALA 152.A O no hydrogen 3.050 N/A THR 156.A OG1 ALA 152.A O no hydrogen 3.050 N/A THR 156.A OG1 TRP 153.A O no hydrogen 2.852 N/A ARG 157.A N TRP 153.A O no hydrogen 3.173 N/A ARG 157.A NE TRP 153.A O no hydrogen 3.021 N/A ARG 157.A NE THR 156.A OG1 no hydrogen 3.246 N/A ARG 157.A NH1 ASP 189.A OD1 no hydrogen 2.784 N/A ARG 157.A NH1 ASP 189.A OD2 no hydrogen 3.536 N/A ARG 157.A NH2 THR 156.A OG1 no hydrogen 3.128 N/A ARG 157.A NH2 ASP 189.A OD2 no hydrogen 2.840 N/A GLU 158.A N GLU 154.A O no hydrogen 2.916 N/A ARG 159.A N PHE 155.A O no hydrogen 2.976 N/A ASN 160.A N ARG 157.A O no hydrogen 3.282 N/A LEU 161.A N THR 156.A O no hydrogen 2.624 N/A ALA 162.A N LYS 131.A O no hydrogen 2.836 N/A LEU 163.A N ASP 189.A OD2 no hydrogen 2.738 N/A HIS 164.A N LEU 133.A O no hydrogen 2.891 N/A HIS 164.A ND1 SER 190.A OG no hydrogen 2.958 N/A HIS 164.A NE2 ASN 62.A OD1 no hydrogen 3.045 N/A VAL 165.A N SER 190.A O no hydrogen 3.203 N/A ASP 166.A N LEU 135.A O no hydrogen 2.624 N/A GLY 167.A N THR 192.A OG1 no hydrogen 2.824 N/A ALA 168.A N ASP 166.A OD1 no hydrogen 3.264 N/A ARG 169.A NE ASP 7.A OD2 no hydrogen 2.657 N/A ARG 169.A NH2 ASP 7.A OD1 no hydrogen 2.909 N/A ILE 170.A N GLY 167.A O no hydrogen 3.114 N/A ASN 172.A ND2 HIS 253.A NE2 no hydrogen 3.029 N/A ALA 173.A N ARG 169.A O no hydrogen 3.357 N/A VAL 174.A N ILE 170.A O no hydrogen 2.861 N/A VAL 175.A N PHE 171.A O no hydrogen 3.271 N/A ALA 176.A N ASN 172.A O no hydrogen 3.358 N/A TYR 177.A N ALA 173.A O no hydrogen 2.730 N/A TYR 177.A OH LEU 144.A O no hydrogen 2.287 N/A GLY 178.A N VAL 174.A O no hydrogen 2.877 N/A CYS 179.A N VAL 174.A O no hydrogen 3.386 N/A CYS 179.A SG GLU 180.A O no hydrogen 3.276 N/A GLU 180.A N GLU 183.A OE1 no hydrogen 2.852 N/A GLU 183.A N GLU 180.A O no hydrogen 3.114 N/A ILE 184.A N LEU 181.A O no hydrogen 2.891 N/A THR 185.A N LEU 181.A O no hydrogen 2.913 N/A THR 185.A OG1 SER 47.A O no hydrogen 2.653 N/A THR 185.A OG1 LEU 181.A O no hydrogen 3.188 N/A THR 185.A OG1 LYS 182.A O no hydrogen 3.242 N/A GLN 186.A N LYS 182.A O no hydrogen 3.345 N/A GLN 186.A NE2 GLU 183.A O no hydrogen 2.780 N/A TYR 187.A N ILE 184.A O no hydrogen 3.265 N/A CYS 188.A N THR 185.A O no hydrogen 3.200 N/A CYS 188.A SG THR 185.A O no hydrogen 3.248 N/A CYS 188.A SG SER 190.A O no hydrogen 3.488 N/A ASP 189.A N LEU 163.A O no hydrogen 2.912 N/A SER 190.A N LEU 163.A O no hydrogen 3.412 N/A SER 190.A OG HIS 69.A NE2 no hydrogen 2.688 N/A SER 190.A OG HIS 164.A ND1 no hydrogen 2.958 N/A PHE 191.A N VAL 208.A O no hydrogen 3.088 N/A THR 192.A N VAL 165.A O no hydrogen 3.224 N/A THR 192.A OG1 ASP 166.A OD1 no hydrogen 3.185 N/A ILE 193.A N LEU 206.A O no hydrogen 2.817 N/A LEU 195.A N GLY 204.A O no hydrogen 2.905 N/A THR 201.A N LEU 195.A O no hydrogen 2.867 N/A THR 201.A OG1 VAL 203.A O no hydrogen 3.266 N/A SER 205.A N LEU 55.A O no hydrogen 2.838 N/A SER 205.A OG ILE 193.A O no hydrogen 3.064 N/A LEU 206.A N ILE 193.A O no hydrogen 2.650 N/A LEU 207.A N ILE 53.A O no hydrogen 3.019 N/A VAL 208.A N PHE 191.A O no hydrogen 3.111 N/A GLY 209.A N ALA 51.A O no hydrogen 3.095 N/A ARG 211.A N GLU 50.A OE2 no hydrogen 2.860 N/A TYR 213.A N ASN 210.A OD1 no hydrogen 2.839 N/A TYR 213.A OH ALA 65.A O no hydrogen 2.836 N/A ILE 214.A N ASN 210.A O no hydrogen 3.015 N/A LYS 215.A N ARG 211.A O no hydrogen 3.060 N/A ARG 216.A N ASP 212.A O no hydrogen 3.229 N/A ARG 216.A NE SER 68.A O no hydrogen 3.275 N/A ARG 216.A NH2 SER 68.A O no hydrogen 2.921 N/A ALA 217.A N TYR 213.A O no hydrogen 2.978 N/A ILE 218.A N ILE 214.A O no hydrogen 2.878 N/A TRP 220.A N ARG 216.A O no hydrogen 3.193 N/A ARG 221.A N ALA 217.A O no hydrogen 2.935 N/A ARG 221.A NH1 PHE 54.A O no hydrogen 2.774 N/A LYS 222.A N ILE 218.A O no hydrogen 3.197 N/A MET 223.A N ARG 219.A O no hydrogen 3.204 N/A THR 224.A N TRP 220.A O no hydrogen 2.969 N/A THR 224.A OG1 TRP 220.A O no hydrogen 2.794 N/A THR 224.A OG1 ARG 221.A O no hydrogen 3.009 N/A GLY 225.A N LYS 222.A O no hydrogen 3.195 N/A GLY 226.A N ARG 221.A O no hydrogen 2.731 N/A ARG 229.A NE ASP 27.A OD1 no hydrogen 2.896 N/A ARG 229.A NE ASP 27.A OD2 no hydrogen 2.981 N/A ARG 229.A NH2 ASP 27.A OD2 no hydrogen 2.907 N/A GLY 232.A N ASP 33.A OD2 no hydrogen 2.849 N/A LEU 234.A N SER 231.A O no hydrogen 3.018 N/A ALA 235.A N SER 231.A O no hydrogen 2.937 N/A ALA 236.A N GLY 232.A O no hydrogen 2.801 N/A ALA 237.A N LEU 234.A O no hydrogen 3.132 N/A GLY 238.A N LEU 234.A O no hydrogen 3.364 N/A ILE 239.A N ALA 235.A O no hydrogen 2.966 N/A TYR 240.A N ALA 236.A O no hydrogen 3.108 N/A ALA 241.A N ALA 237.A O no hydrogen 2.999 N/A LEU 242.A N GLY 238.A O no hydrogen 3.013 N/A LYS 243.A N ILE 239.A O no hydrogen 3.279 N/A LYS 243.A N TYR 240.A O no hydrogen 3.269 N/A ASN 244.A N ALA 241.A O no hydrogen 3.397 N/A ASN 244.A ND2 TYR 240.A O no hydrogen 2.795 N/A ASN 245.A N ALA 241.A O no hydrogen 2.810 N/A ASN 245.A ND2 LEU 199.A O no hydrogen 2.753 N/A ARG 248.A NH1 ASP 252.A OD2 no hydrogen 3.087 N/A ARG 248.A NH2 ASP 252.A OD1 no hydrogen 2.955 N/A LEU 249.A N VAL 246.A O no hydrogen 3.200 N/A GLN 250.A N ALA 247.A O no hydrogen 3.296 N/A GLN 250.A NE2 GLN 250.A O no hydrogen 3.346 N/A GLN 250.A NE2 ASP 254.A OD2 no hydrogen 2.853 N/A GLU 251.A N ARG 248.A O no hydrogen 3.018 N/A HIS 253.A N LEU 249.A O no hydrogen 3.159 N/A ASP 254.A N GLN 250.A O no hydrogen 2.912 N/A ASN 255.A N GLU 251.A O no hydrogen 2.877 N/A ALA 256.A N ASP 252.A O no hydrogen 3.023 N/A ALA 257.A N HIS 253.A O no hydrogen 2.985 N/A TRP 258.A N ASP 254.A O no hydrogen 2.772 N/A MET 259.A N ASN 255.A O no hydrogen 2.674 N/A ALA 260.A N ALA 256.A O no hydrogen 2.931 N/A GLU 261.A N ALA 257.A O no hydrogen 3.267 N/A GLN 262.A N TRP 258.A O no hydrogen 3.098 N/A LEU 263.A N MET 259.A O no hydrogen 3.004 N/A ARG 264.A N ALA 260.A O no hydrogen 2.957 N/A GLU 265.A N GLU 261.A O no hydrogen 2.943 N/A ALA 266.A N GLN 262.A O no hydrogen 2.977 N/A GLY 267.A N ARG 264.A O no hydrogen 3.315 N/A ALA 268.A N LEU 263.A O no hydrogen 2.779 N/A VAL 270.A N ALA 268.A O no hydrogen 3.043 N/A MET 271.A N PHE 279.A O no hydrogen 2.671 N/A ARG 272.A NH1 ASN 140.A O no hydrogen 3.243 N/A ARG 272.A NH1 ASP 274.A OD2 no hydrogen 2.745 N/A ARG 272.A NH2 ASN 140.A O no hydrogen 3.215 N/A GLN 273.A NE2 THR 275.A O no hydrogen 2.790 N/A ASP 274.A N MET 277.A O no hydrogen 2.899 N/A THR 275.A OG1 GLY 141.A O no hydrogen 2.723 N/A THR 275.A OG1 ASP 274.A O no hydrogen 2.542 N/A ASN 276.A ND2 ASP 7.A OD2 no hydrogen 3.347 N/A ASN 276.A ND2 THR 311.A O no hydrogen 3.003 N/A MET 277.A N ASP 274.A O no hydrogen 2.870 N/A LEU 278.A N LEU 309.A O no hydrogen 3.032 N/A PHE 279.A N ARG 272.A O no hydrogen 3.032 N/A VAL 280.A N VAL 307.A O no hydrogen 2.938 N/A ARG 281.A N ASP 269.A O no hydrogen 2.749 N/A VAL 282.A N VAL 280.A O no hydrogen 3.212 N/A LEU 290.A N ASN 286.A O no hydrogen 2.874 N/A GLY 291.A N ALA 287.A O no hydrogen 3.223 N/A GLU 292.A N ALA 288.A O no hydrogen 3.176 N/A TYR 293.A N ALA 289.A O no hydrogen 2.853 N/A MET 294.A N LEU 290.A O no hydrogen 2.918 N/A LYS 295.A N GLY 291.A O no hydrogen 2.973 N/A ALA 296.A N GLU 292.A O no hydrogen 3.132 N/A ARG 297.A N MET 294.A O no hydrogen 3.087 N/A ARG 297.A NE TYR 293.A O no hydrogen 2.739 N/A ASN 298.A N LYS 295.A O no hydrogen 3.079 N/A VAL 299.A N MET 294.A O no hydrogen 2.759 N/A LEU 300.A N ILE 2.A O no hydrogen 2.704 N/A VAL 307.A N VAL 280.A O no hydrogen 2.883 N/A ARG 308.A NH2 ARG 5.A O no hydrogen 3.031 N/A LEU 309.A N LEU 278.A O no hydrogen 2.843 N/A VAL 310.A N LEU 4.A O no hydrogen 3.230 N/A THR 311.A N ASN 276.A O no hydrogen 2.996 N/A THR 311.A OG1 ASP 252.A O no hydrogen 2.662 N/A THR 311.A OG1 ASN 276.A O no hydrogen 3.429 N/A HIS 312.A NE2 ASP 3.A O no hydrogen 2.565 N/A ASP 314.A N HIS 312.A ND1 no hydrogen 3.142 N/A VAL 315.A N HIS 312.A O no hydrogen 3.080 N/A SER 316.A N GLN 319.A OE1 no hydrogen 2.859 N/A SER 316.A OG GLN 319.A OE1 no hydrogen 3.391 N/A ARG 317.A NE ASN 255.A OD1 no hydrogen 2.881 N/A ARG 317.A NH2 ASN 255.A OD1 no hydrogen 3.244 N/A GLN 319.A N SER 316.A OG no hydrogen 3.307 N/A LEU 320.A N SER 316.A O no hydrogen 2.909 N/A ALA 321.A N ARG 317.A O no hydrogen 2.731 N/A GLU 322.A N GLU 318.A O no hydrogen 3.305 N/A VAL 323.A N GLN 319.A O no hydrogen 3.103 N/A ALA 324.A N LEU 320.A O no hydrogen 2.841 N/A ALA 325.A N ALA 321.A O no hydrogen 3.014 N/A HIS 326.A N GLU 322.A O no hydrogen 3.069 N/A TRP 327.A N VAL 323.A O no hydrogen 2.826 N/A ARG 328.A N ALA 324.A O no hydrogen 2.937 N/A ALA 329.A N ALA 325.A O no hydrogen 2.955 N/A PHE 330.A N HIS 326.A O no hydrogen 2.890 N/A LEU 331.A N TRP 327.A O no hydrogen 3.168 N/A LEU 331.A N ARG 328.A O no hydrogen 3.276 N/A