Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3wov_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLY 2.A N THR 1.A OG1 no hydrogen 2.781 N/A VAL 6.A N GLY 2.A O no hydrogen 3.028 N/A LEU 7.A N TRP 3.A O no hydrogen 2.917 N/A LYS 8.A N GLU 4.A O no hydrogen 2.904 N/A LYS 8.A N GLN 5.A O no hydrogen 3.277 N/A TRP 9.A N GLN 5.A O no hydrogen 3.270 N/A THR 14.A OG1 LEU 10.A O no hydrogen 2.561 N/A SER 15.A OG ASP 356.A OD1 no hydrogen 2.740 N/A TYR 17.A OH ASP 402.A OD1 no hydrogen 2.948 N/A THR 19.A N ASN 63.A OD1 no hydrogen 2.961 N/A THR 19.A OG1 GLU 61.A O no hydrogen 2.374 N/A THR 19.A OG1 ASN 63.A OD1 no hydrogen 3.048 N/A THR 21.A N TYR 64.A O no hydrogen 3.100 N/A SER 22.A OG TRP 23.A O no hydrogen 3.485 N/A GLY 27.A N ASP 25.A OD2 no hydrogen 2.641 N/A TYR 28.A N ASP 25.A O no hydrogen 3.198 N/A TRP 29.A N TYR 26.A O no hydrogen 2.924 N/A ILE 30.A N GLY 27.A O no hydrogen 2.954 N/A GLU 31.A N GLY 27.A O no hydrogen 3.231 N/A SER 32.A N TYR 28.A O no hydrogen 2.746 N/A SER 32.A OG TYR 28.A O no hydrogen 3.018 N/A ARG 38.A N ASP 37.A OD2 no hydrogen 2.748 N/A ASP 39.A N ALA 35.A O no hydrogen 3.154 N/A HIS 40.A N ASP 37.A O no hydrogen 3.243 N/A LEU 42.A N ARG 38.A O no hydrogen 2.910 N/A ALA 43.A N ASP 39.A O no hydrogen 2.882 N/A LEU 44.A N HIS 40.A O no hydrogen 2.916 N/A PHE 45.A N ILE 41.A O no hydrogen 2.950 N/A LEU 46.A N LEU 42.A O no hydrogen 2.904 N/A ALA 47.A N ALA 43.A O no hydrogen 2.905 N/A ARG 48.A NH1 GLY 82.A O no hydrogen 3.093 N/A ARG 48.A NH1 GLU 381.A OE2 no hydrogen 2.504 N/A ARG 48.A NH2 GLU 381.A OE2 no hydrogen 3.129 N/A SER 53.A N GLY 50.A O no hydrogen 2.924 N/A SER 53.A OG GLY 50.A O no hydrogen 2.828 N/A GLU 54.A N ASN 51.A O no hydrogen 3.020 N/A VAL 55.A N SER 53.A O no hydrogen 2.667 N/A SER 59.A OG ASP 56.A O no hydrogen 2.425 N/A TRP 60.A N PHE 57.A O no hydrogen 3.133 N/A GLU 61.A N GLU 58.A O no hydrogen 2.948 N/A LEU 62.A N PHE 57.A O no hydrogen 3.173 N/A ASN 63.A N THR 19.A O no hydrogen 3.177 N/A TYR 64.A N THR 19.A O no hydrogen 3.198 N/A PHE 65.A N TYR 227.A O no hydrogen 2.860 N/A ILE 66.A N THR 21.A O no hydrogen 2.914 N/A ILE 67.A N ILE 225.A O no hydrogen 2.915 N/A LEU 69.A N ASN 223.A O no hydrogen 2.853 N/A ASN 70.A ND2 TYR 68.A OH no hydrogen 2.786 N/A ASP 71.A N TYR 68.A O no hydrogen 2.886 N/A TRP 72.A N LEU 69.A O no hydrogen 2.976 N/A ALA 73.A N ASN 70.A O no hydrogen 2.935 N/A LYS 74.A N ASP 71.A O no hydrogen 2.921 N/A LYS 74.A NZ TRP 24.A O no hydrogen 2.785 N/A LYS 74.A NZ ASP 25.A OD1 no hydrogen 2.472 N/A LYS 74.A NZ ASP 71.A OD1 no hydrogen 2.851 N/A PHE 75.A N TRP 72.A O no hydrogen 2.948 N/A ASN 76.A ND2 GLU 89.A O no hydrogen 3.631 N/A ASN 76.A ND2 TYR 90.A O no hydrogen 3.428 N/A ASN 76.A ND2 VAL 100.A O no hydrogen 2.785 N/A ILE 78.A N LYS 74.A O no hydrogen 3.096 N/A SER 79.A N PHE 75.A O no hydrogen 2.638 N/A SER 79.A OG PHE 75.A O no hydrogen 2.709 N/A TYR 80.A N ASN 76.A O no hydrogen 3.226 N/A LEU 81.A N ALA 77.A O no hydrogen 3.077 N/A GLY 82.A N SER 79.A O no hydrogen 2.939 N/A ALA 84.A N SER 79.A O no hydrogen 2.924 N/A THR 86.A N GLU 89.A OE1 no hydrogen 3.191 N/A ARG 87.A N ALA 378.A O no hydrogen 3.153 N/A ARG 87.A NE TYR 80.A OH no hydrogen 3.112 N/A TYR 90.A N ARG 87.A O no hydrogen 2.903 N/A ASN 91.A N ARG 87.A O no hydrogen 2.922 N/A GLY 92.A N ARG 87.A O no hydrogen 3.477 N/A VAL 100.A N GLU 89.A O no hydrogen 2.901 N/A THR 102.A N ASN 76.A OD1 no hydrogen 3.091 N/A THR 102.A OG1 ASN 76.A OD1 no hydrogen 3.112 N/A LEU 104.A N ILE 182.A O no hydrogen 2.880 N/A LEU 106.A N GLY 180.A O no hydrogen 2.904 N/A GLN 107.A N VAL 114.A O no hydrogen 2.737 N/A GLY 110.A N PRO 177.A O no hydrogen 3.071 N/A ILE 112.A N SER 109.A O no hydrogen 2.945 N/A TYR 113.A N VAL 122.A O no hydrogen 2.952 N/A TYR 113.A OH ALA 176.A O no hydrogen 2.574 N/A VAL 114.A N GLN 107.A O no hydrogen 2.579 N/A ASN 115.A N ILE 120.A O no hydrogen 2.929 N/A ASN 115.A ND2 PRO 105.A O no hydrogen 2.410 N/A ALA 118.A N ASN 115.A OD1 no hydrogen 3.168 N/A GLY 119.A N ASN 115.A O no hydrogen 3.089 N/A SER 121.A N ASN 136.A O no hydrogen 2.904 N/A VAL 122.A N TYR 113.A O no hydrogen 2.858 N/A ARG 123.A N THR 134.A O no hydrogen 2.889 N/A VAL 124.A N GLY 111.A O no hydrogen 3.269 N/A VAL 125.A N LYS 132.A O no hydrogen 3.200 N/A SER 127.A N THR 130.A O no hydrogen 3.100 N/A SER 127.A OG ASN 128.A O no hydrogen 3.357 N/A THR 129.A OG1 THR 129.A O no hydrogen 2.602 N/A THR 130.A N SER 127.A O no hydrogen 3.016 N/A THR 130.A OG1 THR 129.A O no hydrogen 2.512 N/A THR 134.A N ARG 123.A O no hydrogen 2.910 N/A VAL 135.A N CYS 143.A O no hydrogen 3.046 N/A VAL 137.A N ALA 141.A O no hydrogen 3.202 N/A ARG 138.A N ASN 136.A OD1 no hydrogen 2.710 N/A CYS 143.A N VAL 135.A O no hydrogen 2.962 N/A SER 144.A N ARG 162.A O no hydrogen 2.974 N/A ILE 146.A N TYR 171.A O no hydrogen 2.994 N/A THR 148.A N ILE 157.A O no hydrogen 2.929 N/A LEU 149.A N LEU 173.A O no hydrogen 2.869 N/A LEU 150.A N LYS 155.A O no hydrogen 2.959 N/A ILE 151.A N LEU 175.A O no hydrogen 2.681 N/A ASN 154.A N LEU 150.A O no hydrogen 2.445 N/A LYS 155.A NZ SER 131.A OG no hydrogen 2.789 N/A ILE 157.A N THR 148.A O no hydrogen 2.876 N/A GLY 159.A N ILE 146.A O no hydrogen 3.009 N/A ASN 160.A N SER 144.A OG no hydrogen 2.835 N/A GLY 161.A N SER 144.A O no hydrogen 2.819 N/A CYS 163.A SG ARG 140.A O no hydrogen 3.736 N/A CYS 163.A SG GLU 142.A O no hydrogen 3.952 N/A GLY 166.A N CYS 163.A O no hydrogen 2.922 N/A PHE 169.A N GLY 161.A O no hydrogen 2.826 N/A VAL 172.A N THR 183.A O no hydrogen 2.867 N/A LEU 173.A N TYR 147.A O no hydrogen 2.961 N/A TYR 174.A N LEU 181.A O no hydrogen 2.868 N/A TYR 174.A OH ALA 188.A O no hydrogen 2.603 N/A LEU 175.A N LEU 149.A O no hydrogen 2.899 N/A ALA 176.A N PHE 179.A O no hydrogen 2.780 N/A GLY 180.A N LEU 106.A O no hydrogen 2.880 N/A ILE 182.A N LEU 104.A O no hydrogen 2.886 N/A THR 183.A N VAL 172.A O no hydrogen 2.915 N/A THR 183.A OG1 VAL 172.A O no hydrogen 3.329 N/A TYR 184.A N THR 102.A O no hydrogen 2.897 N/A TYR 184.A OH GLU 89.A OE2 no hydrogen 2.489 N/A TYR 185.A N PRO 170.A O no hydrogen 3.053 N/A LYS 186.A NZ GLU 89.A OE1 no hydrogen 2.939 N/A LYS 186.A NZ GLU 89.A OE2 no hydrogen 3.086 N/A VAL 187.A N TYR 184.A O no hydrogen 3.069 N/A THR 189.A OG1 ASP 49.A OD2 no hydrogen 2.800 N/A SER 190.A N VAL 187.A O no hydrogen 3.190 N/A SER 190.A OG VAL 187.A O no hydrogen 3.006 N/A ASN 191.A N ARG 48.A O no hydrogen 3.053 N/A ASN 191.A ND2 PHE 45.A O no hydrogen 2.851 N/A ASN 191.A ND2 SER 53.A OG no hydrogen 2.818 N/A PHE 192.A N LEU 46.A O no hydrogen 2.967 N/A LYS 194.A N SER 190.A O no hydrogen 3.224 N/A LYS 194.A NZ ASP 49.A OD1 no hydrogen 2.924 N/A LYS 194.A NZ THR 189.A O no hydrogen 2.909 N/A LYS 194.A NZ ASN 191.A OD1 no hydrogen 2.952 N/A LEU 195.A N ASN 191.A O no hydrogen 2.909 N/A LEU 195.A N PHE 192.A O no hydrogen 3.239 N/A ALA 196.A N PHE 192.A O no hydrogen 2.864 N/A PHE 197.A N ILE 193.A O no hydrogen 3.401 N/A ILE 199.A N ILE 193.A O no hydrogen 3.415 N/A ILE 201.A N ILE 199.A O no hydrogen 2.870 N/A SER 202.A OG ASP 49.A OD1 no hydrogen 2.991 N/A SER 202.A OG ASP 49.A OD2 no hydrogen 3.071 N/A SER 202.A OG TYR 204.A O no hydrogen 3.365 N/A LYS 203.A N ASP 49.A OD2 no hydrogen 2.765 N/A TYR 204.A N SER 202.A OG no hydrogen 3.104 N/A GLU 209.A N GLU 209.A OE1 no hydrogen 2.724 N/A LYS 210.A N GLY 206.A O no hydrogen 3.419 N/A LYS 210.A NZ GLY 206.A O no hydrogen 3.521 N/A LEU 211.A N PHE 207.A O no hydrogen 2.893 N/A TYR 212.A N THR 208.A O no hydrogen 2.944 N/A TYR 212.A OH LYS 194.A O no hydrogen 2.631 N/A SER 213.A N LYS 210.A O no hydrogen 2.833 N/A SER 213.A OG LYS 210.A O no hydrogen 3.000 N/A ASN 214.A N LYS 210.A O no hydrogen 2.977 N/A ASN 214.A ND2 ARG 230.A O no hydrogen 2.951 N/A ASN 214.A ND2 SER 263.A O no hydrogen 3.163 N/A PHE 215.A N LEU 211.A O no hydrogen 2.827 N/A VAL 216.A N GLU 228.A O no hydrogen 3.057 N/A VAL 218.A N VAL 226.A O no hydrogen 2.963 N/A ASN 223.A N THR 1.A O no hydrogen 3.332 N/A ASN 223.A ND2 ASN 70.A OD1 no hydrogen 3.017 N/A ILE 225.A N ILE 67.A O no hydrogen 2.917 N/A VAL 226.A N TYR 219.A O no hydrogen 2.902 N/A TYR 227.A N PHE 65.A O no hydrogen 2.898 N/A TYR 227.A OH LEU 195.A O no hydrogen 2.542 N/A GLU 228.A N VAL 216.A O no hydrogen 2.519 N/A PHE 229.A N ASN 63.A O no hydrogen 2.916 N/A ARG 230.A N ASN 214.A O no hydrogen 2.705 N/A ARG 230.A NE GLU 228.A OE1 no hydrogen 2.952 N/A ARG 230.A NH2 GLU 228.A OE1 no hydrogen 3.408 N/A ALA 233.A N SER 263.A O no hydrogen 2.933 N/A ILE 234.A N MET 450.A O no hydrogen 3.195 N/A TYR 235.A N TYR 261.A O no hydrogen 2.917 N/A GLU 238.A N LYS 259.A O no hydrogen 2.976 N/A GLU 239.A N LYS 246.A O no hydrogen 2.885 N/A LEU 240.A N GLU 257.A O no hydrogen 3.049 N/A ILE 241.A N THR 244.A O no hydrogen 2.878 N/A THR 244.A N ILE 241.A O no hydrogen 2.918 N/A LYS 246.A N GLU 239.A O no hydrogen 2.912 N/A VAL 248.A N ILE 237.A O no hydrogen 2.658 N/A LEU 251.A N ARG 454.A O no hydrogen 2.858 N/A THR 252.A OG1 PRO 253.A O no hydrogen 3.422 N/A GLY 254.A N LEU 308.A O no hydrogen 2.904 N/A HIS 256.A N VAL 306.A O no hydrogen 2.889 N/A HIS 256.A ND1 GLU 239.A OE1 no hydrogen 2.902 N/A LEU 258.A N VAL 304.A O no hydrogen 2.894 N/A LYS 259.A N GLU 238.A O no hydrogen 2.549 N/A LYS 259.A NZ TYR 261.A OH no hydrogen 3.254 N/A LEU 260.A N ILE 302.A O no hydrogen 2.857 N/A TYR 261.A N ARG 236.A O no hydrogen 2.870 N/A TYR 261.A OH GLU 238.A OE1 no hydrogen 3.094 N/A SER 263.A N ALA 233.A O no hydrogen 2.832 N/A SER 263.A OG ASN 214.A OD1 no hydrogen 2.657 N/A ALA 264.A N GLU 299.A OE2 no hydrogen 2.701 N/A PHE 265.A N PRO 231.A O no hydrogen 2.512 N/A GLY 266.A N GLU 54.A OE1 no hydrogen 3.321 N/A ARG 267.A NE ASP 56.A OD1 no hydrogen 2.897 N/A ARG 267.A NH2 ASP 56.A OD1 no hydrogen 3.226 N/A ARG 267.A NH2 ASP 56.A OD2 no hydrogen 2.924 N/A ILE 269.A N MET 294.A O no hydrogen 3.035 N/A ARG 270.A N GLN 320.A OE1 no hydrogen 3.369 N/A ASN 271.A N GLU 292.A O no hydrogen 2.907 N/A ALA 272.A N ILE 291.A O no hydrogen 2.728 N/A THR 273.A N VAL 319.A O no hydrogen 2.916 N/A LEU 274.A N GLY 289.A O no hydrogen 2.605 N/A TYR 275.A N VAL 317.A O no hydrogen 2.875 N/A VAL 276.A N ILE 286.A O no hydrogen 2.885 N/A TYR 277.A N ARG 315.A O no hydrogen 2.901 N/A TYR 277.A OH GLU 447.A OE2 no hydrogen 2.490 N/A ALA 278.A N GLU 284.A O no hydrogen 2.920 N/A ILE 279.A N LYS 313.A O no hydrogen 2.891 N/A GLU 284.A N LYS 282.A O no hydrogen 3.169 N/A LYS 285.A NZ TYR 277.A OH no hydrogen 2.682 N/A LYS 285.A NZ GLU 447.A OE2 no hydrogen 3.346 N/A ILE 286.A N VAL 276.A O no hydrogen 2.893 N/A LYS 287.A NZ GLU 290.A OE2 no hydrogen 2.938 N/A ILE 288.A N LEU 274.A O no hydrogen 2.916 N/A GLY 289.A N LEU 274.A O no hydrogen 3.392 N/A ILE 291.A N ALA 272.A O no hydrogen 3.135 N/A TYR 293.A OH ASP 268.A OD2 no hydrogen 3.327 N/A MET 294.A N ILE 269.A O no hydrogen 3.240 N/A HIS 296.A ND1 ASP 268.A OD1 no hydrogen 2.304 N/A LEU 297.A N ASN 295.A OD1 no hydrogen 3.102 N/A GLU 299.A N GLU 299.A OE1 no hydrogen 3.364 N/A ILE 302.A N LEU 260.A O no hydrogen 2.888 N/A VAL 304.A N LEU 258.A O no hydrogen 2.905 N/A VAL 306.A N HIS 256.A O no hydrogen 2.894 N/A LEU 308.A N GLY 254.A O no hydrogen 2.871 N/A LYS 313.A N ILE 279.A O no hydrogen 2.914 N/A TYR 314.A N VAL 453.A O no hydrogen 2.902 N/A TYR 314.A OH PRO 309.A O no hydrogen 2.603 N/A ARG 315.A N TYR 277.A O no hydrogen 2.902 N/A LEU 316.A N ALA 451.A O no hydrogen 2.877 N/A VAL 317.A N TYR 275.A O no hydrogen 2.926 N/A LEU 318.A N TYR 448.A O no hydrogen 2.628 N/A VAL 319.A N THR 273.A O no hydrogen 2.907 N/A GLN 320.A N LYS 446.A O no hydrogen 3.150 N/A GLY 322.A N ALA 444.A O no hydrogen 2.985 N/A VAL 324.A N PHE 442.A O no hydrogen 2.604 N/A VAL 326.A N GLY 354.A O no hydrogen 3.224 N/A THR 328.A N LYS 352.A O no hydrogen 3.179 N/A THR 328.A OG1 ASP 402.A OD2 no hydrogen 3.468 N/A ILE 338.A N ASN 336.A OD1 no hydrogen 3.143 N/A ARG 339.A N ASN 336.A O no hydrogen 3.202 N/A ARG 339.A NE ILE 436.A O no hydrogen 3.253 N/A ILE 340.A N VAL 438.A O no hydrogen 3.277 N/A GLY 344.A N MET 411.A O no hydrogen 2.898 N/A VAL 353.A N ASN 403.A O no hydrogen 2.889 N/A GLY 354.A N VAL 326.A O no hydrogen 3.170 N/A VAL 355.A N GLY 401.A O no hydrogen 2.916 N/A TYR 359.A N LEU 398.A O no hydrogen 2.914 N/A ALA 361.A N ILE 396.A O no hydrogen 2.916 N/A ASP 362.A N ILE 443.A O no hydrogen 3.054 N/A LEU 363.A N LYS 393.A O no hydrogen 2.881 N/A TYR 364.A N VAL 441.A O no hydrogen 3.039 N/A LEU 365.A N THR 390.A O no hydrogen 2.683 N/A ARG 366.A N GLU 439.A O no hydrogen 2.661 N/A ARG 366.A NH1 SER 59.A O no hydrogen 2.839 N/A ARG 366.A NH2 SER 59.A O no hydrogen 2.766 N/A ALA 367.A N PHE 387.A O no hydrogen 2.894 N/A THR 368.A N ARG 437.A O no hydrogen 2.877 N/A PHE 369.A N ASP 385.A O no hydrogen 2.896 N/A ILE 370.A N GLY 435.A O no hydrogen 2.921 N/A TYR 371.A N HIS 383.A O no hydrogen 2.960 N/A TYR 371.A OH ASP 385.A OD2 no hydrogen 2.400 N/A LEU 372.A N ILE 432.A O no hydrogen 2.872 N/A VAL 373.A N GLU 381.A O no hydrogen 2.927 N/A ARG 374.A N LYS 430.A O no hydrogen 3.020 N/A LYS 375.A N ALA 379.A O no hydrogen 2.829 N/A LYS 375.A NZ GLY 83.A O no hydrogen 2.432 N/A LYS 375.A NZ GLU 381.A OE2 no hydrogen 3.264 N/A GLU 381.A N VAL 373.A O no hydrogen 2.874 N/A HIS 383.A N TYR 371.A O no hydrogen 2.837 N/A ASP 385.A N PHE 369.A O no hydrogen 2.898 N/A PHE 387.A N ALA 367.A O no hydrogen 2.954 N/A ILE 389.A N LEU 365.A O no hydrogen 2.701 N/A LEU 392.A N LEU 363.A O no hydrogen 2.555 N/A ILE 396.A N ALA 361.A O no hydrogen 2.890 N/A LEU 398.A N TYR 359.A O no hydrogen 2.882 N/A LYS 400.A N ASP 358.A OD1 no hydrogen 3.038 N/A GLY 401.A N VAL 355.A O no hydrogen 2.921 N/A ASN 403.A N VAL 353.A O no hydrogen 2.898 N/A ASN 403.A ND2 HIS 399.A ND1 no hydrogen 3.090 N/A SER 417.A OG GLU 343.A OE1 no hydrogen 2.717 N/A SER 417.A OG GLU 343.A OE2 no hydrogen 2.600 N/A SER 418.A N GLY 414.A O no hydrogen 2.793 N/A SER 418.A OG GLY 414.A O no hydrogen 2.877 N/A SER 418.A OG VAL 415.A O no hydrogen 2.734 N/A TYR 419.A N VAL 415.A O no hydrogen 2.942 N/A TYR 419.A OH ASP 385.A OD2 no hydrogen 2.377 N/A LYS 420.A N ILE 416.A O no hydrogen 2.908 N/A GLU 421.A N SER 417.A O no hydrogen 3.093 N/A GLU 421.A N SER 418.A O no hydrogen 3.244 N/A LYS 422.A N TYR 419.A O no hydrogen 3.050 N/A LYS 422.A NZ SER 418.A OG no hydrogen 3.426 N/A LEU 423.A N TYR 419.A O no hydrogen 3.159 N/A LYS 425.A NZ LYS 422.A O no hydrogen 2.730 N/A GLU 426.A N LEU 423.A O no hydrogen 2.891 N/A TYR 427.A N LEU 423.A O no hydrogen 2.880 N/A ILE 432.A N LEU 372.A O no hydrogen 2.905 N/A ARG 434.A N ILE 370.A O no hydrogen 2.928 N/A GLY 435.A N ILE 370.A O no hydrogen 3.016 N/A ARG 437.A N THR 368.A O no hydrogen 2.985 N/A VAL 438.A N ILE 338.A O no hydrogen 3.095 N/A GLU 439.A N ARG 366.A O no hydrogen 2.989 N/A VAL 441.A N TYR 364.A O no hydrogen 3.013 N/A ILE 443.A N ASP 362.A O no hydrogen 3.103 N/A ALA 444.A N GLY 322.A O no hydrogen 3.091 N/A LYS 446.A N GLN 320.A O no hydrogen 2.710 N/A LYS 446.A NZ GLU 58.A OE2 no hydrogen 2.793 N/A LYS 446.A NZ PRO 323.A O no hydrogen 2.274 N/A TYR 448.A N LEU 318.A O no hydrogen 2.661 N/A TYR 448.A OH GLU 58.A OE2 no hydrogen 3.218 N/A MET 450.A N LEU 316.A O no hydrogen 2.807 N/A ALA 451.A N LEU 316.A O no hydrogen 2.972 N/A VAL 453.A N TYR 314.A O no hydrogen 2.878 N/A