Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3wx0_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 1.A N GLU 25.A O no hydrogen 2.360 N/A LEU 2.A N GLU 25.A O no hydrogen 2.576 N/A ALA 3.A N ALA 46.A O no hydrogen 3.332 N/A VAL 4.A N GLU 27.A O no hydrogen 2.796 N/A TYR 5.A N CYS 48.A O no hydrogen 3.001 N/A TYR 5.A OH THR 40.A OG1 no hydrogen 2.757 N/A SER 6.A N PHE 31.A O no hydrogen 3.261 N/A SER 6.A OG ASP 53.A OD1 no hydrogen 2.268 N/A SER 6.A OG ASP 53.A OD2 no hydrogen 2.956 N/A THR 7.A N PHE 29.A O no hydrogen 3.194 N/A THR 7.A OG1 PHE 29.A O no hydrogen 2.414 N/A LYS 8.A N ASP 11.A OD2 no hydrogen 3.107 N/A LYS 12.A N LYS 8.A O no hydrogen 3.078 N/A LYS 13.A N GLN 9.A O no hydrogen 2.651 N/A TYR 14.A N TYR 10.A O no hydrogen 3.331 N/A LEU 15.A N ASP 11.A O no hydrogen 3.009 N/A GLN 16.A N LYS 12.A O no hydrogen 3.259 N/A GLN 17.A N LYS 13.A O no hydrogen 3.335 N/A VAL 18.A N TYR 14.A O no hydrogen 3.118 N/A ASN 19.A N LEU 15.A O no hydrogen 2.668 N/A ASN 19.A ND2 PHE 24.A O no hydrogen 3.049 N/A GLU 20.A N GLN 17.A O no hydrogen 3.260 N/A SER 21.A N VAL 18.A O no hydrogen 3.126 N/A GLY 23.A N ASN 19.A O no hydrogen 2.426 N/A PHE 24.A N ASN 19.A OD1 no hydrogen 2.561 N/A GLU 27.A N LEU 2.A O no hydrogen 2.706 N/A PHE 29.A N VAL 4.A O no hydrogen 2.742 N/A LEU 33.A N ASP 53.A OD1 no hydrogen 3.417 N/A THR 34.A OG1 LEU 33.A O no hydrogen 2.581 N/A THR 37.A OG1 LEU 32.A O no hydrogen 3.023 N/A THR 37.A OG1 THR 34.A O no hydrogen 3.529 N/A ALA 38.A N GLU 35.A O no hydrogen 3.294 N/A THR 40.A N THR 37.A O no hydrogen 3.202 N/A THR 40.A OG1 TYR 5.A OH no hydrogen 2.757 N/A THR 40.A OG1 THR 37.A O no hydrogen 2.290 N/A ALA 41.A N ALA 38.A O no hydrogen 3.410 N/A ASN 42.A N LYS 39.A O no hydrogen 2.974 N/A GLU 45.A N LYS 1.A O no hydrogen 3.204 N/A ALA 46.A N LYS 1.A O no hydrogen 3.439 N/A VAL 47.A N TYR 70.A O no hydrogen 3.017 N/A CYS 48.A N ALA 3.A O no hydrogen 3.025 N/A ILE 49.A N ALA 72.A O no hydrogen 3.048 N/A ASP 53.A N PHE 50.A O no hydrogen 3.302 N/A SER 56.A N ASP 54.A OD1 no hydrogen 2.872 N/A SER 56.A OG ASP 54.A OD1 no hydrogen 2.368 N/A SER 56.A OG ASP 54.A OD2 no hydrogen 2.744 N/A LEU 60.A N SER 56.A O no hydrogen 3.402 N/A GLU 61.A N ARG 57.A O no hydrogen 2.965 N/A GLU 62.A N PRO 58.A O no hydrogen 2.954 N/A LEU 63.A N VAL 59.A O no hydrogen 2.876 N/A LYS 64.A N LEU 60.A O no hydrogen 2.948 N/A LYS 65.A N GLU 61.A O no hydrogen 2.903 N/A HIS 66.A N LEU 63.A O no hydrogen 3.232 N/A HIS 66.A ND1 ASN 42.A OD1 no hydrogen 2.218 N/A HIS 66.A NE2 GLU 62.A OE2 no hydrogen 2.546 N/A GLY 67.A N LYS 64.A O no hydrogen 2.335 N/A VAL 68.A N LEU 63.A O no hydrogen 3.059 N/A LYS 69.A N GLU 45.A O no hydrogen 2.504 N/A LYS 69.A NZ TYR 70.A OH no hydrogen 3.285 N/A TYR 70.A N GLU 45.A O no hydrogen 3.195 N/A ILE 71.A N LYS 92.A O no hydrogen 3.205 N/A ALA 72.A N VAL 47.A O no hydrogen 2.978 N/A ARG 74.A N ILE 49.A O no hydrogen 3.369 N/A ARG 74.A NH1 TYR 5.A O no hydrogen 2.341 N/A ARG 74.A NH2 TYR 5.A O no hydrogen 3.156 N/A ARG 74.A NH2 SER 6.A O no hydrogen 2.546 N/A CYS 75.A SG GLY 77.A O no hydrogen 3.265 N/A ALA 76.A N TYR 99.A OH no hydrogen 3.173 N/A ASN 79.A ND2 ASN 79.A O no hydrogen 2.290 N/A ASN 80.A N ASN 80.A OD1 no hydrogen 2.286 N/A ASN 80.A ND2 PHE 50.A O no hydrogen 3.225 N/A ASN 80.A ND2 ASP 53.A O no hydrogen 2.756 N/A ASP 82.A N GLY 55.A O no hydrogen 3.514 N/A ALA 85.A N ASP 82.A OD1 no hydrogen 3.318 N/A ALA 86.A N ASP 82.A O no hydrogen 3.328 N/A LYS 87.A N LEU 83.A O no hydrogen 2.963 N/A GLU 88.A N ASP 84.A O no hydrogen 3.008 N/A LEU 89.A N ALA 85.A O no hydrogen 2.968 N/A LEU 89.A N ALA 86.A O no hydrogen 3.029 N/A GLY 90.A N LYS 87.A O no hydrogen 2.733 N/A LEU 91.A N ALA 86.A O no hydrogen 2.950 N/A VAL 94.A N ILE 71.A O no hydrogen 2.788 N/A ARG 95.A NH1 ALA 76.A O no hydrogen 2.940 N/A ALA 105.A N PRO 101.A O no hydrogen 3.270 N/A GLU 106.A N GLU 102.A O no hydrogen 2.862 N/A HIS 107.A N ALA 103.A O no hydrogen 2.839 N/A HIS 107.A NE2 THR 275.A OG1 no hydrogen 3.128 N/A ALA 108.A N VAL 104.A O no hydrogen 3.090 N/A ILE 109.A N ALA 105.A O no hydrogen 3.262 N/A GLY 110.A N GLU 106.A O no hydrogen 2.987 N/A MET 111.A N HIS 107.A O no hydrogen 2.930 N/A MET 112.A N ALA 108.A O no hydrogen 3.130 N/A MET 113.A N ILE 109.A O no hydrogen 2.763 N/A THR 114.A N GLY 110.A O no hydrogen 2.874 N/A THR 114.A OG1 GLY 110.A O no hydrogen 2.857 N/A LEU 115.A N MET 111.A O no hydrogen 2.725 N/A ASN 116.A N MET 112.A O no hydrogen 2.831 N/A ASN 116.A ND2 PHE 139.A O no hydrogen 2.941 N/A ARG 117.A N MET 113.A O no hydrogen 3.082 N/A ARG 118.A N LEU 115.A O no hydrogen 3.185 N/A ARG 118.A NE LEU 115.A O no hydrogen 3.139 N/A ARG 118.A NE ASN 116.A O no hydrogen 3.312 N/A ILE 119.A N THR 114.A O no hydrogen 3.142 N/A HIS 120.A N HIS 120.A ND1 no hydrogen 2.741 N/A ARG 121.A NH2 ALA 268.A O no hydrogen 3.256 N/A ARG 121.A NH2 HIS 270.A O no hydrogen 3.419 N/A ALA 122.A N ARG 118.A O no hydrogen 2.958 N/A TYR 123.A N ILE 119.A O no hydrogen 3.132 N/A ARG 125.A N ARG 121.A O no hydrogen 3.200 N/A ARG 125.A NH1 SER 132.A O no hydrogen 2.599 N/A ARG 125.A NH1 GLU 134.A O no hydrogen 3.016 N/A ARG 125.A NH2 GLU 134.A O no hydrogen 2.571 N/A THR 126.A N ALA 122.A O no hydrogen 2.529 N/A ARG 127.A N TYR 123.A O no hydrogen 2.906 N/A ALA 129.A N THR 126.A O no hydrogen 2.301 N/A ASN 130.A N ARG 125.A O no hydrogen 2.768 N/A SER 132.A N ASN 130.A OD1 no hydrogen 2.929 N/A LEU 136.A N LEU 133.A O no hydrogen 3.373 N/A PHE 139.A N ASN 116.A OD1 no hydrogen 2.852 N/A LYS 144.A N MET 141.A O no hydrogen 3.084 N/A THR 145.A N ASP 198.A OD1 no hydrogen 2.757 N/A ALA 146.A N ARG 168.A O no hydrogen 2.787 N/A GLY 147.A N VAL 199.A O no hydrogen 2.601 N/A VAL 148.A N LEU 170.A O no hydrogen 2.987 N/A ILE 149.A N SER 201.A O no hydrogen 3.027 N/A GLY 150.A N PHE 172.A O no hydrogen 3.113 N/A THR 151.A N ASP 173.A OD1 no hydrogen 2.882 N/A THR 151.A OG1 TYR 175.A O no hydrogen 3.565 N/A VAL 156.A N GLY 152.A O no hydrogen 3.139 N/A ALA 157.A N LYS 153.A O no hydrogen 3.089 N/A MET 158.A N ILE 154.A O no hydrogen 2.963 N/A LEU 159.A N GLY 155.A O no hydrogen 3.091 N/A ARG 160.A N VAL 156.A O no hydrogen 2.917 N/A ILE 161.A N ALA 157.A O no hydrogen 3.336 N/A LEU 162.A N MET 158.A O no hydrogen 2.911 N/A LYS 163.A N LEU 159.A O no hydrogen 2.858 N/A LYS 163.A NZ LEU 183.A O no hydrogen 2.821 N/A GLY 164.A N ARG 160.A O no hydrogen 3.191 N/A GLY 164.A N ILE 161.A O no hydrogen 2.864 N/A PHE 165.A N LEU 162.A O no hydrogen 2.870 N/A GLY 166.A N LYS 163.A O no hydrogen 3.163 N/A ARG 168.A N LYS 144.A O no hydrogen 2.856 N/A LEU 170.A N ALA 146.A O no hydrogen 2.991 N/A ALA 171.A N GLU 186.A O no hydrogen 3.194 N/A PHE 172.A N VAL 148.A O no hydrogen 3.017 N/A SER 177.A N TYR 187.A OH no hydrogen 3.039 N/A ALA 180.A N SER 177.A OG no hydrogen 2.706 N/A LEU 181.A N SER 177.A O no hydrogen 2.935 N/A GLU 182.A N ALA 178.A O no hydrogen 2.780 N/A LEU 183.A N ALA 180.A O no hydrogen 3.220 N/A GLY 184.A N LEU 181.A O no hydrogen 2.965 N/A GLU 186.A N LEU 169.A O no hydrogen 3.005 N/A VAL 188.A N ALA 171.A O no hydrogen 3.127 N/A THR 192.A N ASP 189.A OD2 no hydrogen 2.426 N/A THR 192.A OG1 ASP 189.A OD1 no hydrogen 2.738 N/A THR 192.A OG1 ASP 189.A OD2 no hydrogen 2.472 N/A LEU 193.A N ASP 189.A O no hydrogen 2.841 N/A PHE 194.A N LEU 190.A O no hydrogen 2.440 N/A SER 195.A N PRO 191.A O no hydrogen 3.130 N/A SER 195.A OG PRO 191.A O no hydrogen 3.131 N/A SER 195.A OG THR 192.A O no hydrogen 3.214 N/A GLU 196.A N THR 192.A O no hydrogen 2.915 N/A SER 197.A N LEU 193.A O no hydrogen 3.122 N/A SER 197.A OG LEU 193.A O no hydrogen 2.904 N/A ASP 198.A N THR 145.A O no hydrogen 3.103 N/A VAL 199.A N THR 145.A O no hydrogen 3.369 N/A ILE 200.A N MET 227.A O no hydrogen 2.956 N/A SER 201.A N GLY 147.A O no hydrogen 3.034 N/A SER 201.A OG HIS 203.A NE2 no hydrogen 2.575 N/A LEU 202.A N VAL 229.A O no hydrogen 3.305 N/A HIS 203.A N ILE 149.A O no hydrogen 2.791 N/A CYS 204.A N SER 232.A OG no hydrogen 3.277 N/A THR 207.A N ASN 210.A OD1 no hydrogen 2.861 N/A ASN 210.A N THR 207.A O no hydrogen 3.067 N/A ASN 210.A ND2 PRO 205.A O no hydrogen 3.189 N/A TYR 211.A OH HIS 212.A NE2 no hydrogen 3.426 N/A HIS 212.A N ALA 235.A O no hydrogen 2.684 N/A LEU 214.A N LEU 236.A O no hydrogen 2.821 N/A ALA 218.A N ASN 215.A OD1 no hydrogen 3.058 N/A PHE 219.A N ASN 215.A O no hydrogen 2.932 N/A ASP 220.A N GLU 216.A O no hydrogen 3.203 N/A GLN 221.A N ALA 218.A O no hydrogen 3.132 N/A MET 222.A N PHE 219.A O no hydrogen 2.943 N/A LYS 223.A NZ GLU 196.A O no hydrogen 3.426 N/A LYS 223.A NZ ASP 198.A OD2 no hydrogen 3.567 N/A MET 227.A N ASP 198.A O no hydrogen 3.386 N/A ILE 228.A N SER 253.A O no hydrogen 3.138 N/A VAL 229.A N ILE 200.A O no hydrogen 2.968 N/A ASN 230.A N GLY 255.A O no hydrogen 2.588 N/A ASN 230.A ND2 ARG 233.A O no hydrogen 3.272 N/A SER 232.A OG LEU 202.A O no hydrogen 2.266 N/A ILE 237.A N GLY 234.A O no hydrogen 3.165 N/A ASP 238.A N LEU 214.A O no hydrogen 2.876 N/A ALA 241.A N ASP 238.A OD1 no hydrogen 3.525 N/A ALA 242.A N ASP 238.A O no hydrogen 2.743 N/A ILE 243.A N SER 239.A O no hydrogen 2.842 N/A GLU 244.A N GLN 240.A O no hydrogen 3.185 N/A ALA 245.A N ALA 241.A O no hydrogen 3.234 N/A LEU 246.A N ALA 242.A O no hydrogen 3.014 N/A LYS 247.A N ILE 243.A O no hydrogen 3.093 N/A ASN 248.A N GLU 244.A O no hydrogen 2.974 N/A GLN 249.A N LEU 246.A O no hydrogen 2.992 N/A LYS 250.A N ALA 245.A O no hydrogen 2.877 N/A LYS 250.A NZ ASP 220.A OD1 no hydrogen 2.302 N/A GLY 252.A N VAL 226.A O no hydrogen 2.774 N/A SER 253.A N VAL 226.A O no hydrogen 3.212 N/A LEU 254.A N ASN 271.A O no hydrogen 2.965 N/A GLY 255.A N ILE 228.A O no hydrogen 2.728 N/A MET 256.A N LEU 273.A O no hydrogen 3.111 N/A ASP 257.A N ASN 230.A O no hydrogen 3.116 N/A VAL 258.A N THR 275.A O no hydrogen 2.631 N/A ARG 264.A NH1 ASP 261.A OD1 no hydrogen 2.549 N/A ARG 265.A N ASP 261.A O no hydrogen 3.327 N/A LEU 266.A N VAL 262.A O no hydrogen 2.876 N/A SER 267.A N PHE 263.A O no hydrogen 2.626 N/A SER 267.A OG PHE 263.A O no hydrogen 2.486 N/A ALA 268.A N ARG 264.A O no hydrogen 3.030 N/A CYS 269.A N ARG 265.A O no hydrogen 3.006 N/A CYS 269.A SG ARG 265.A O no hydrogen 3.193 N/A ASN 271.A ND2 LEU 115.A O no hydrogen 3.046 N/A LEU 273.A N LEU 254.A O no hydrogen 3.112 N/A THR 275.A N MET 256.A O no hydrogen 2.973 N/A THR 275.A OG1 HIS 107.A NE2 no hydrogen 3.128 N/A THR 275.A OG1 ASP 257.A OD1 no hydrogen 2.596 N/A HIS 277.A N THR 275.A O no hydrogen 2.893 N/A HIS 277.A ND1 GLU 260.A OE1 no hydrogen 2.838 N/A GLN 278.A N ASP 257.A OD1 no hydrogen 2.984 N/A LEU 281.A N GLN 278.A O no hydrogen 2.902 N/A THR 282.A N PHE 280.A O no hydrogen 2.668 N/A THR 282.A OG1 PHE 280.A O no hydrogen 3.509 N/A GLU 284.A N GLU 284.A OE1 no hydrogen 1.874 N/A ALA 285.A N THR 282.A OG1 no hydrogen 3.008 N/A LEU 286.A N THR 282.A O no hydrogen 2.832 N/A THR 287.A N ALA 283.A O no hydrogen 2.749 N/A THR 287.A OG1 ALA 283.A O no hydrogen 2.236 N/A SER 288.A N GLU 284.A O no hydrogen 3.047 N/A SER 288.A OG ASP 100.A OD1 no hydrogen 3.552 N/A SER 288.A OG GLU 284.A O no hydrogen 2.781 N/A ILE 289.A N ALA 285.A O no hydrogen 3.269 N/A SER 290.A N LEU 286.A O no hydrogen 3.077 N/A SER 290.A OG LEU 286.A O no hydrogen 3.162 N/A GLN 291.A N THR 287.A O no hydrogen 2.883 N/A THR 292.A N SER 288.A O no hydrogen 2.953 N/A THR 292.A OG1 SER 288.A O no hydrogen 3.036 N/A THR 293.A N ILE 289.A O no hydrogen 2.994 N/A THR 293.A OG1 LEU 73.A O no hydrogen 2.780 N/A LEU 294.A N SER 290.A O no hydrogen 2.792 N/A GLN 295.A N GLN 291.A O no hydrogen 2.707 N/A ASN 296.A N THR 292.A O no hydrogen 3.128 N/A ASN 296.A ND2 ARG 95.A O no hydrogen 2.643 N/A SER 298.A N LEU 294.A O no hydrogen 2.921 N/A ASN 299.A N GLN 295.A O no hydrogen 2.986 N/A LEU 300.A N LEU 297.A O no hydrogen 3.270 N/A GLU 301.A N SER 298.A O no hydrogen 2.851 N/A