Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 3wxg_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 4.A N GLU 4.A OE1 no hydrogen 2.770 N/A MET 6.A N LEU 3.A O no hydrogen 2.651 N/A GLY 8.A N VAL 251.A O no hydrogen 2.709 N/A LYS 11.A N PRO 249.A O no hydrogen 3.331 N/A LYS 11.A NZ VAL 5.A O no hydrogen 2.602 N/A LYS 11.A NZ HIS 70.A O no hydrogen 3.234 N/A GLY 12.A N GLY 71.A O no hydrogen 2.775 N/A GLN 14.A N VAL 73.A O no hydrogen 2.972 N/A GLN 14.A NE2 ASN 247.A O no hydrogen 2.901 N/A GLY 15.A N SER 235.A O no hydrogen 3.174 N/A HIS 16.A N SER 19.A OG no hydrogen 2.531 N/A ASN 18.A ND2 SER 96.A O no hydrogen 3.034 N/A SER 19.A OG HIS 16.A O no hydrogen 3.142 N/A SER 19.A OG ASP 23.A OD2 no hydrogen 2.827 N/A TYR 21.A OH PHE 94.A O no hydrogen 3.250 N/A LEU 22.A N SER 19.A O no hydrogen 2.634 N/A ASP 23.A N SER 19.A O no hydrogen 3.131 N/A SER 24.A N ALA 20.A O no hydrogen 3.079 N/A SER 24.A OG ALA 20.A O no hydrogen 3.410 N/A SER 24.A OG TYR 217.A O no hydrogen 3.022 N/A THR 25.A OG1 TYR 21.A O no hydrogen 2.787 N/A LEU 26.A N LEU 22.A O no hydrogen 2.928 N/A PHE 27.A N ASP 23.A O no hydrogen 3.010 N/A CYS 28.A N SER 24.A O no hydrogen 3.006 N/A CYS 28.A SG SER 24.A O no hydrogen 3.196 N/A LEU 29.A N THR 25.A O no hydrogen 3.098 N/A PHE 30.A N LEU 26.A O no hydrogen 3.191 N/A SER 31.A N PHE 27.A O no hydrogen 3.251 N/A SER 31.A OG PHE 27.A O no hydrogen 2.660 N/A SER 33.A OG GLN 293.A OE1 no hydrogen 3.264 N/A SER 34.A OG ASP 37.A OD2 no hydrogen 3.082 N/A VAL 35.A N SER 33.A OG no hydrogen 3.067 N/A ASP 37.A N SER 34.A O no hydrogen 3.339 N/A LEU 40.A N ASP 37.A O no hydrogen 2.736 N/A LEU 41.A N THR 38.A O no hydrogen 2.674 N/A ARG 42.A N THR 38.A O no hydrogen 2.948 N/A SER 45.A N ASP 48.A OD2 no hydrogen 3.055 N/A THR 47.A N SER 45.A OG no hydrogen 3.010 N/A TYR 52.A N VAL 49.A O no hydrogen 3.308 N/A TYR 52.A OH ARG 42.A O no hydrogen 2.575 N/A THR 55.A N TYR 51.A O no hydrogen 3.084 N/A THR 55.A OG1 TYR 51.A O no hydrogen 2.949 N/A GLN 56.A N TYR 52.A O no hydrogen 3.019 N/A GLN 56.A NE2 VAL 39.A O no hydrogen 3.420 N/A GLN 56.A NE2 ARG 42.A O no hydrogen 2.418 N/A GLU 57.A N LYS 53.A O no hydrogen 2.857 N/A LEU 58.A N GLU 54.A O no hydrogen 3.025 N/A LEU 59.A N THR 55.A O no hydrogen 3.018 N/A ARG 60.A N GLN 56.A O no hydrogen 3.096 N/A ARG 60.A NH1 LEU 40.A O no hydrogen 2.707 N/A ARG 60.A NH1 GLN 56.A OE1 no hydrogen 2.128 N/A ARG 60.A NH2 GLU 57.A OE2 no hydrogen 3.293 N/A THR 61.A N GLU 57.A O no hydrogen 2.952 N/A THR 61.A OG1 GLU 57.A O no hydrogen 2.477 N/A GLU 62.A N LEU 58.A O no hydrogen 2.995 N/A VAL 64.A N LEU 59.A O no hydrogen 2.693 N/A ASN 65.A N ARG 60.A O no hydrogen 2.624 N/A LEU 67.A N ILE 63.A O no hydrogen 2.972 N/A ARG 68.A N VAL 64.A O no hydrogen 2.943 N/A ARG 68.A NE PHE 30.A O no hydrogen 2.920 N/A ARG 68.A NH1 ASP 37.A OD2 no hydrogen 3.211 N/A ARG 68.A NH2 PHE 30.A O no hydrogen 2.766 N/A ARG 68.A NH2 ASP 37.A OD1 no hydrogen 2.896 N/A ARG 68.A NH2 ASP 37.A OD2 no hydrogen 3.215 N/A ILE 69.A N ASN 65.A O no hydrogen 2.876 N/A HIS 70.A N PRO 66.A O no hydrogen 3.164 N/A GLY 71.A N PRO 66.A O no hydrogen 3.261 N/A VAL 73.A N GLY 12.A O no hydrogen 3.046 N/A ALA 75.A N GLN 14.A OE1 no hydrogen 2.883 N/A LYS 77.A N CYS 74.A O no hydrogen 3.392 N/A LYS 77.A NZ GLU 62.A OE1 no hydrogen 3.095 N/A ILE 78.A N ALA 75.A O no hydrogen 2.769 N/A MET 79.A N ALA 75.A O no hydrogen 2.994 N/A LYS 80.A N THR 76.A O no hydrogen 3.456 N/A LYS 80.A NZ GLU 62.A OE1 no hydrogen 3.349 N/A LEU 81.A N LYS 77.A O no hydrogen 3.408 N/A ARG 82.A N ILE 78.A O no hydrogen 2.977 N/A ARG 82.A NH1 TYR 21.A OH no hydrogen 3.461 N/A ARG 82.A NH1 PHE 94.A O no hydrogen 2.351 N/A ARG 82.A NH2 TYR 17.A O no hydrogen 2.323 N/A ARG 83.A N MET 79.A O no hydrogen 2.933 N/A ILE 84.A N LYS 80.A O no hydrogen 3.174 N/A LEU 85.A N LEU 81.A O no hydrogen 2.986 N/A GLU 86.A N ARG 82.A O no hydrogen 3.006 N/A LYS 87.A N ARG 83.A O no hydrogen 3.091 N/A LYS 87.A N ILE 84.A O no hydrogen 2.710 N/A VAL 88.A N LEU 85.A O no hydrogen 3.268 N/A SER 92.A OG GLU 89.A O no hydrogen 2.369 N/A THR 95.A N GLU 86.A OE1 no hydrogen 3.503 N/A THR 95.A OG1 GLU 86.A OE1 no hydrogen 3.204 N/A THR 95.A OG1 GLU 86.A OE2 no hydrogen 2.521 N/A SER 96.A N GLY 93.A O no hydrogen 3.381 N/A GLU 97.A N GLY 93.A O no hydrogen 2.812 N/A LYS 99.A NZ SER 92.A O no hydrogen 2.647 N/A LYS 99.A NZ GLU 103.A OE2 no hydrogen 3.458 N/A GLU 102.A N ASP 100.A OD1 no hydrogen 2.637 N/A PHE 104.A N ASP 100.A O no hydrogen 3.012 N/A LEU 105.A N PRO 101.A O no hydrogen 2.604 N/A ASN 106.A N GLU 102.A O no hydrogen 2.841 N/A ASN 106.A ND2 GLU 102.A OE1 no hydrogen 3.467 N/A ILE 107.A N GLU 103.A O no hydrogen 3.174 N/A LEU 108.A N PHE 104.A O no hydrogen 3.101 N/A PHE 109.A N LEU 105.A O no hydrogen 2.839 N/A HIS 110.A N ASN 106.A O no hydrogen 2.982 N/A HIS 111.A N ILE 107.A O no hydrogen 2.972 N/A ILE 112.A N LEU 108.A O no hydrogen 3.048 N/A LEU 113.A N LEU 108.A O no hydrogen 3.217 N/A VAL 115.A N PHE 109.A O no hydrogen 3.066 N/A LEU 119.A N CYS 131.A O no hydrogen 2.984 N/A LEU 121.A N GLN 129.A O no hydrogen 2.853 N/A ARG 122.A N LYS 163.A O no hydrogen 2.683 N/A SER 123.A OG ASP 161.A O no hydrogen 2.670 N/A ALA 124.A N ASP 161.A O no hydrogen 3.091 N/A GLN 126.A N SER 123.A O no hydrogen 2.623 N/A GLN 129.A N LEU 121.A O no hydrogen 2.871 N/A CYS 131.A N LEU 119.A O no hydrogen 3.455 N/A TYR 132.A OH VAL 115.A O no hydrogen 2.647 N/A TYR 134.A N ILE 172.A O no hydrogen 2.916 N/A TYR 134.A OH SER 156.A O no hydrogen 3.068 N/A TYR 134.A OH SER 156.A OG no hydrogen 2.652 N/A GLN 135.A NE2 ILE 136.A O no hydrogen 2.658 N/A GLN 135.A NE2 MET 175.A O no hydrogen 2.808 N/A ILE 136.A N GLN 174.A O no hydrogen 3.099 N/A PHE 137.A N SER 156.A OG no hydrogen 3.081 N/A LYS 143.A N LYS 140.A O no hydrogen 2.802 N/A LYS 143.A NZ ASP 139.A O no hydrogen 2.730 N/A THR 148.A N GLN 151.A OE1 no hydrogen 3.131 N/A SER 149.A N PHE 189.A O no hydrogen 3.027 N/A SER 149.A OG TYR 292.A OH no hydrogen 2.701 N/A GLN 150.A N SER 191.A OG no hydrogen 3.002 N/A GLN 151.A N THR 148.A OG1 no hydrogen 2.927 N/A LEU 152.A N THR 148.A O no hydrogen 3.040 N/A LEU 153.A N SER 149.A O no hydrogen 2.709 N/A GLU 154.A N GLN 150.A O no hydrogen 2.780 N/A TRP 155.A N GLN 151.A O no hydrogen 2.622 N/A SER 156.A N LEU 152.A O no hydrogen 2.641 N/A SER 156.A OG TYR 134.A OH no hydrogen 2.652 N/A SER 156.A OG PHE 137.A O no hydrogen 3.384 N/A PHE 157.A N LEU 153.A O no hydrogen 2.758 N/A ILE 158.A N GLU 154.A O no hydrogen 2.862 N/A ASN 159.A N TRP 155.A O no hydrogen 3.236 N/A LEU 162.A N PHE 157.A O no hydrogen 2.945 N/A LYS 163.A NZ ASP 198.A O no hydrogen 3.197 N/A PHE 164.A N LEU 199.A O no hydrogen 2.627 N/A ALA 165.A N ARG 120.A O no hydrogen 2.965 N/A LEU 171.A N TYR 292.A O no hydrogen 2.699 N/A ILE 173.A N CYS 290.A O no hydrogen 2.815 N/A GLN 174.A N TYR 134.A O no hydrogen 2.794 N/A MET 175.A N TYR 288.A O no hydrogen 2.591 N/A ARG 177.A NE ALA 287.A O no hydrogen 3.474 N/A ARG 177.A NH1 ILE 212.A O no hydrogen 2.461 N/A ARG 177.A NH1 ALA 287.A O no hydrogen 3.353 N/A ARG 177.A NH2 ILE 212.A O no hydrogen 3.136 N/A ARG 177.A NH2 GLU 213.A O no hydrogen 3.470 N/A PHE 178.A N PHE 182.A O no hydrogen 2.911 N/A LYS 183.A NZ GLU 213.A O no hydrogen 3.384 N/A LYS 183.A NZ ASP 286.A OD1 no hydrogen 3.304 N/A MET 184.A N PRO 176.A O no hydrogen 3.209 N/A LYS 187.A NZ LEU 268.A O no hydrogen 3.248 N/A LYS 187.A NZ HIS 269.A O no hydrogen 3.364 N/A LYS 187.A NZ LEU 271.A O no hydrogen 3.232 N/A ILE 188.A N LEU 284.A O no hydrogen 3.049 N/A PHE 189.A N PRO 147.A O no hydrogen 2.753 N/A SER 191.A N SER 149.A OG no hydrogen 2.525 N/A SER 191.A OG SER 149.A OG no hydrogen 3.140 N/A LEU 194.A N MET 204.A O no hydrogen 2.697 N/A ASP 195.A N GLN 150.A OE1 no hydrogen 2.699 N/A ILE 196.A N GLN 202.A O no hydrogen 3.056 N/A THR 197.A N ASP 195.A OD1 no hydrogen 2.761 N/A THR 197.A OG1 ASP 195.A OD1 no hydrogen 2.398 N/A THR 197.A OG1 GLN 202.A O no hydrogen 3.551 N/A LEU 199.A N ILE 196.A O no hydrogen 2.846 N/A MET 204.A N LEU 194.A O no hydrogen 2.738 N/A GLU 205.A N GLN 293.A O no hydrogen 2.623 N/A LEU 206.A N LEU 192.A O no hydrogen 2.945 N/A PHE 207.A N MET 291.A O no hydrogen 2.815 N/A ALA 208.A N MET 291.A O no hydrogen 3.435 N/A VAL 209.A N PHE 220.A O no hydrogen 2.946 N/A LEU 210.A N MET 289.A O no hydrogen 2.760 N/A CYS 211.A N VAL 218.A O no hydrogen 2.802 N/A CYS 211.A SG ARG 282.A O no hydrogen 3.290 N/A ILE 212.A N ASP 286.A O no hydrogen 2.869 N/A HIS 216.A NE2 ASP 234.A OD1 no hydrogen 2.711 N/A VAL 218.A N CYS 211.A O no hydrogen 3.076 N/A ALA 219.A N PHE 233.A O no hydrogen 3.006 N/A PHE 220.A N VAL 209.A O no hydrogen 2.881 N/A VAL 221.A N LEU 231.A O no hydrogen 2.982 N/A LYS 222.A N PHE 207.A O no hydrogen 3.278 N/A LYS 222.A NZ GLY 224.A O no hydrogen 2.977 N/A LYS 222.A NZ ALA 226.A O no hydrogen 3.347 N/A TYR 223.A N ALA 229.A O no hydrogen 2.847 N/A SER 225.A OG MET 297.A O no hydrogen 2.268 N/A TRP 230.A N SER 228.A O no hydrogen 2.569 N/A LEU 231.A N VAL 221.A O no hydrogen 2.866 N/A PHE 232.A N SER 252.A O no hydrogen 2.807 N/A PHE 233.A N ALA 219.A O no hydrogen 2.768 N/A ASP 234.A N GLN 250.A O no hydrogen 2.945 N/A SER 235.A OG ASP 23.A OD2 no hydrogen 2.987 N/A MET 236.A N ASP 234.A OD1 no hydrogen 2.995 N/A ALA 237.A N ILE 248.A O no hydrogen 3.152 N/A ASP 238.A N ILE 248.A O no hydrogen 3.148 N/A ARG 239.A N ASP 238.A OD1 no hydrogen 2.501 N/A ARG 239.A NE ASN 247.A OD1 no hydrogen 2.879 N/A ARG 239.A NH1 GLY 242.A O no hydrogen 2.918 N/A ARG 239.A NH1 GLN 243.A O no hydrogen 3.530 N/A ARG 239.A NH2 ASN 247.A OD1 no hydrogen 3.445 N/A ASP 240.A N PHE 246.A O no hydrogen 3.138 N/A PHE 246.A N ASP 240.A O no hydrogen 3.111 N/A ASN 247.A ND2 GLY 15.A O no hydrogen 3.310 N/A ILE 248.A N ASP 238.A O no hydrogen 2.450 N/A GLN 250.A N ASP 234.A O no hydrogen 2.924 N/A VAL 251.A N GLY 8.A O no hydrogen 2.881 N/A SER 252.A N PHE 232.A O no hydrogen 2.850 N/A CYS 254.A N TRP 230.A O no hydrogen 3.113 N/A VAL 257.A N CYS 254.A O no hydrogen 3.116 N/A GLY 258.A N PRO 255.A O no hydrogen 2.495 N/A GLU 259.A N PRO 255.A O no hydrogen 3.248 N/A TYR 260.A N GLU 256.A O no hydrogen 2.962 N/A LEU 261.A N VAL 257.A O no hydrogen 3.121 N/A LYS 262.A N GLU 259.A O no hydrogen 3.124 N/A LYS 262.A NZ ASP 227.A OD2 no hydrogen 2.810 N/A LYS 262.A NZ GLU 259.A OE2 no hydrogen 3.041 N/A MET 263.A N TYR 260.A O no hydrogen 3.112 N/A GLU 267.A N THR 264.A OG1 no hydrogen 3.117 N/A LEU 268.A N THR 264.A O no hydrogen 2.989 N/A HIS 269.A N PRO 265.A O no hydrogen 2.726 N/A ALA 270.A N GLU 266.A O no hydrogen 3.458 N/A LEU 271.A N LEU 268.A O no hydrogen 3.157 N/A LYS 274.A N ASP 272.A OD1 no hydrogen 3.133 N/A ASN 275.A N ASP 272.A O no hydrogen 2.794 N/A ILE 276.A N PRO 273.A O no hydrogen 3.185 N/A GLN 277.A N TYR 260.A OH no hydrogen 3.274 N/A GLN 277.A NE2 ASN 275.A O no hydrogen 3.177 N/A TYR 279.A N GLU 256.A OE2 no hydrogen 3.272 N/A ARG 282.A N TYR 279.A O no hydrogen 3.204 N/A LEU 284.A N ALA 280.A O no hydrogen 3.072 N/A CYS 285.A N ARG 281.A O no hydrogen 2.942 N/A CYS 285.A SG ASN 186.A O no hydrogen 3.670 N/A ASP 286.A N ARG 282.A O no hydrogen 2.755 N/A TYR 288.A N LEU 210.A O no hydrogen 2.821 N/A TYR 288.A OH ASP 100.A OD1 no hydrogen 2.760 N/A MET 289.A N LEU 210.A O no hydrogen 3.234 N/A CYS 290.A N ILE 173.A O no hydrogen 2.822 N/A MET 291.A N ALA 208.A O no hydrogen 2.920 N/A TYR 292.A N LEU 171.A O no hydrogen 2.832 N/A TYR 292.A OH SER 149.A OG no hydrogen 2.701 N/A TYR 292.A OH SER 191.A O no hydrogen 2.307 N/A GLN 293.A N GLU 205.A O no hydrogen 2.799 N/A SER 294.A N SER 169.A O no hydrogen 3.189 N/A SER 294.A OG SER 169.A O no hydrogen 3.295 N/A THR 296.A N GLU 205.A OE1 no hydrogen 2.584 N/A THR 296.A OG1 SER 294.A O no hydrogen 3.444 N/A MET 297.A N GLU 205.A OE1 no hydrogen 2.876 N/A SER 298.A N GLU 205.A OE1 no hydrogen 3.347 N/A SER 298.A OG GLU 193.A OE2 no hydrogen 2.781 N/A