Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4a5l_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 1.A N ASN 2.A O no hydrogen 3.518 N/A HIS 4.A N LEU 108.A O no hydrogen 3.031 N/A VAL 7.A N SER 111.A O no hydrogen 3.166 N/A ILE 8.A N VAL 30.A O no hydrogen 2.758 N/A ILE 9.A N ILE 113.A O no hydrogen 2.809 N/A GLY 10.A N TYR 32.A O no hydrogen 2.883 N/A SER 11.A OG GLU 33.A O no hydrogen 2.903 N/A HIS 16.A N GLY 12.A O no hydrogen 2.939 N/A HIS 16.A ND1 SER 75.A OG no hydrogen 2.862 N/A THR 17.A N PRO 13.A O no hydrogen 3.005 N/A THR 17.A OG1 PRO 13.A O no hydrogen 2.780 N/A ALA 18.A N ALA 14.A O no hydrogen 2.887 N/A ALA 19.A N ALA 15.A O no hydrogen 2.934 N/A ILE 20.A N HIS 16.A O no hydrogen 2.879 N/A TYR 21.A N THR 17.A O no hydrogen 3.120 N/A LEU 22.A N ALA 18.A O no hydrogen 2.871 N/A GLY 23.A N ALA 19.A O no hydrogen 2.772 N/A ARG 24.A N ILE 20.A O no hydrogen 2.925 N/A SER 25.A N TYR 21.A O no hydrogen 3.032 N/A SER 25.A OG TYR 21.A O no hydrogen 3.172 N/A SER 25.A OG GLU 307.A OE1 no hydrogen 2.812 N/A SER 25.A OG GLU 307.A OE2 no hydrogen 2.982 N/A SER 26.A N GLY 23.A O no hydrogen 2.902 N/A LEU 27.A N LEU 22.A O no hydrogen 3.149 N/A VAL 30.A N VAL 6.A O no hydrogen 3.157 N/A MET 31.A N THR 81.A O no hydrogen 2.880 N/A TYR 32.A N ILE 8.A O no hydrogen 2.869 N/A GLU 33.A N ILE 83.A O no hydrogen 2.917 N/A GLY 34.A N GLU 85.A O no hydrogen 3.013 N/A PHE 35.A N THR 86.A OG1 no hydrogen 2.960 N/A GLY 39.A N MET 36.A O no hydrogen 2.744 N/A VAL 40.A N ALA 37.A O no hydrogen 3.195 N/A GLY 43.A N SER 11.A OG no hydrogen 2.958 N/A GLY 44.A N ALA 41.A O no hydrogen 2.978 N/A THR 47.A N GLY 44.A O no hydrogen 2.900 N/A THR 47.A OG1 GLY 44.A O no hydrogen 2.622 N/A THR 48.A N GLN 45.A O no hydrogen 2.923 N/A THR 48.A OG1 GLN 45.A O no hydrogen 2.575 N/A THR 49.A N LEU 46.A O no hydrogen 3.430 N/A ILE 51.A N THR 50.A OG1 no hydrogen 2.732 N/A ILE 52.A N ILE 62.A O no hydrogen 2.738 N/A GLY 61.A N PHE 58.A O no hydrogen 2.948 N/A ILE 62.A N ILE 52.A O no hydrogen 2.983 N/A GLY 64.A N THR 50.A O no hydrogen 2.722 N/A ASN 65.A ND2 THR 47.A O no hydrogen 3.129 N/A GLU 66.A N ASP 63.A OD2 no hydrogen 2.994 N/A LEU 67.A N ASP 63.A O no hydrogen 2.993 N/A MET 68.A N GLY 64.A O no hydrogen 3.043 N/A MET 69.A N.A ASN 65.A O no hydrogen 2.872 N/A MET 69.A N.B ASN 65.A O no hydrogen 2.875 N/A ASN 70.A N GLU 66.A O no hydrogen 2.872 N/A MET 71.A N LEU 67.A O no hydrogen 2.944 N/A ARG 72.A N MET 68.A O no hydrogen 2.938 N/A ARG 72.A NE GLU 33.A OE1 no hydrogen 2.891 N/A ARG 72.A NH2 GLU 33.A OE1 no hydrogen 3.549 N/A ARG 72.A NH2 GLU 33.A OE2 no hydrogen 2.832 N/A THR 73.A N MET 69.A O.A no hydrogen 3.046 N/A THR 73.A N MET 69.A O.B no hydrogen 3.003 N/A THR 73.A OG1 MET 69.A O.A no hydrogen 3.035 N/A THR 73.A OG1 MET 69.A O.B no hydrogen 3.057 N/A GLN 74.A N ASN 70.A O no hydrogen 2.982 N/A SER 75.A N MET 71.A O no hydrogen 2.906 N/A SER 75.A OG HIS 16.A ND1 no hydrogen 2.862 N/A SER 75.A OG HIS 16.A O no hydrogen 3.392 N/A SER 75.A OG MET 71.A O no hydrogen 3.259 N/A GLU 76.A N ARG 72.A O no hydrogen 2.997 N/A LYS 77.A N THR 73.A O no hydrogen 2.803 N/A TYR 78.A N GLN 74.A O no hydrogen 3.215 N/A TYR 78.A N SER 75.A O no hydrogen 3.281 N/A GLY 79.A N GLU 76.A O no hydrogen 2.957 N/A THR 80.A N SER 75.A O no hydrogen 3.099 N/A THR 80.A OG1 SER 75.A O no hydrogen 2.937 N/A THR 81.A N PRO 29.A O no hydrogen 3.129 N/A ILE 83.A N MET 31.A O no hydrogen 2.854 N/A THR 84.A OG1 GLU 33.A OE2 no hydrogen 2.553 N/A ASP 88.A N PHE 100.A O no hydrogen 2.748 N/A HIS 89.A N PHE 100.A O no hydrogen 3.466 N/A HIS 89.A ND1 ASP 88.A OD2 no hydrogen 2.675 N/A ASP 91.A N LYS 98.A O no hydrogen 2.792 N/A SER 93.A N ASP 91.A OD1 no hydrogen 2.888 N/A SER 93.A OG ASP 91.A OD1 no hydrogen 2.704 N/A SER 93.A OG ASP 91.A OD2 no hydrogen 3.540 N/A GLN 95.A NE2 LYS 110.A O no hydrogen 3.460 N/A PHE 97.A N THR 109.A O no hydrogen 2.738 N/A LYS 98.A N ASP 91.A O no hydrogen 3.051 N/A LEU 99.A N VAL 107.A O no hydrogen 2.835 N/A PHE 100.A N HIS 89.A O no hydrogen 2.867 N/A THR 101.A N LYS 105.A O no hydrogen 2.865 N/A GLU 102.A N THR 86.A O no hydrogen 2.918 N/A GLY 104.A N THR 101.A O no hydrogen 2.783 N/A LYS 105.A N THR 101.A OG1 no hydrogen 2.978 N/A VAL 107.A N LEU 99.A O no hydrogen 2.707 N/A THR 109.A N PHE 97.A O no hydrogen 2.953 N/A THR 109.A OG1 HIS 4.A O no hydrogen 3.463 N/A THR 109.A OG1 SER 111.A O no hydrogen 2.801 N/A LYS 110.A N HIS 4.A O no hydrogen 2.930 N/A LYS 110.A NZ HIS 313.A O no hydrogen 2.953 N/A SER 111.A OG ASP 5.A O no hydrogen 2.856 N/A VAL 112.A N GLY 277.A O no hydrogen 3.028 N/A ILE 113.A N VAL 7.A O no hydrogen 2.834 N/A ILE 114.A N PHE 279.A O no hydrogen 2.731 N/A ALA 115.A N ILE 9.A O no hydrogen 2.766 N/A THR 116.A OG1 ASN 250.A O no hydrogen 2.684 N/A THR 119.A N.A SER 248.A O no hydrogen 2.864 N/A THR 119.A N.B SER 248.A O no hydrogen 2.890 N/A THR 119.A OG1.B ASN 250.A OD1 no hydrogen 3.039 N/A LYS 121.A N GLY 246.A O no hydrogen 2.764 N/A ARG 122.A NE GLU 128.A OE2 no hydrogen 2.651 N/A HIS 124.A N GLU 128.A OE2 no hydrogen 3.161 N/A VAL 125.A N GLU 128.A OE1 no hydrogen 3.336 N/A GLU 128.A N VAL 125.A O no hydrogen 2.956 N/A LYS 130.A NZ GLY 217.A O no hydrogen 2.758 N/A TYR 131.A N GLY 127.A O no hydrogen 3.111 N/A TYR 131.A N GLU 128.A O no hydrogen 3.075 N/A GLN 133.A N VAL 136.A O no hydrogen 3.003 N/A ASN 134.A N TYR 131.A O no hydrogen 2.701 N/A VAL 136.A N TYR 131.A O no hydrogen 2.930 N/A SER 137.A N LEU 241.A O no hydrogen 2.906 N/A SER 137.A OG ASP 143.A OD2 no hydrogen 2.566 N/A CYS 139.A N SER 137.A OG no hydrogen 3.054 N/A ASP 143.A N CYS 139.A O no hydrogen 2.850 N/A GLY 144.A N ALA 140.A O no hydrogen 2.935 N/A VAL 146.A N ASP 143.A O no hydrogen 3.087 N/A PHE 149.A N VAL 146.A O no hydrogen 3.001 N/A ARG 150.A N PRO 147.A O no hydrogen 3.001 N/A ARG 150.A NH2 ALA 145.A O no hydrogen 2.756 N/A ASN 151.A N TYR 173.A O no hydrogen 2.802 N/A LYS 152.A N PHE 149.A O no hydrogen 3.129 N/A LEU 154.A N LYS 176.A O no hydrogen 2.894 N/A MET 155.A N GLY 240.A O no hydrogen 2.833 N/A VAL 156.A N ILE 178.A O no hydrogen 2.818 N/A VAL 157.A N PHE 242.A O no hydrogen 2.857 N/A GLY 158.A N LEU 180.A O no hydrogen 2.953 N/A MET 164.A N.A GLY 160.A O no hydrogen 3.098 N/A MET 164.A N.B GLY 160.A O no hydrogen 3.128 N/A GLU 165.A N ASP 161.A O no hydrogen 2.998 N/A GLU 166.A N ALA 162.A O no hydrogen 2.887 N/A ALA 167.A N ALA 163.A O no hydrogen 2.933 N/A LEU 168.A N MET 164.A O.A no hydrogen 2.956 N/A LEU 168.A N MET 164.A O.B no hydrogen 2.960 N/A HIS 169.A N GLU 165.A O no hydrogen 2.992 N/A LEU 170.A N GLU 166.A O no hydrogen 3.031 N/A THR 171.A N ALA 167.A O no hydrogen 3.182 N/A THR 171.A N LEU 168.A O no hydrogen 3.257 N/A THR 171.A OG1 LEU 168.A O no hydrogen 2.643 N/A LYS 172.A N HIS 169.A O no hydrogen 3.188 N/A TYR 173.A N LEU 170.A O no hydrogen 2.954 N/A GLY 174.A N LEU 170.A O no hydrogen 2.889 N/A SER 175.A N LYS 152.A O no hydrogen 2.814 N/A LYS 176.A NZ GLU 203.A OE1 no hydrogen 3.121 N/A LYS 176.A NZ GLU 203.A OE2 no hydrogen 3.422 N/A VAL 177.A N LYS 201.A O no hydrogen 2.863 N/A ILE 178.A N LEU 154.A O no hydrogen 2.736 N/A ILE 179.A N GLU 203.A O no hydrogen 2.842 N/A LEU 180.A N VAL 156.A O no hydrogen 2.815 N/A HIS 181.A N ILE 205.A O no hydrogen 3.037 N/A HIS 181.A NE2 ALA 185.A O no hydrogen 2.859 N/A ARG 187.A N GLY 159.A O no hydrogen 2.824 N/A ALA 188.A N GLY 159.A O no hydrogen 3.223 N/A SER 189.A N ASP 161.A OD1 no hydrogen 2.927 N/A SER 189.A OG ASP 161.A OD1 no hydrogen 3.394 N/A LYS 190.A NZ GLU 194.A OE2 no hydrogen 3.448 N/A MET 192.A N SER 189.A OG no hydrogen 3.354 N/A GLN 193.A N SER 189.A O no hydrogen 2.950 N/A GLU 194.A N LYS 190.A O no hydrogen 2.961 N/A ARG 195.A N THR 191.A O no hydrogen 3.171 N/A VAL 196.A N MET 192.A O no hydrogen 3.124 N/A LEU 197.A N GLN 193.A O no hydrogen 2.639 N/A ASN 198.A N GLU 194.A O no hydrogen 3.277 N/A HIS 199.A N VAL 196.A O no hydrogen 3.156 N/A LYS 201.A N HIS 199.A ND1 no hydrogen 3.007 N/A LYS 201.A NZ THR 171.A O no hydrogen 2.909 N/A LYS 201.A NZ GLY 174.A O no hydrogen 2.784 N/A ILE 202.A N HIS 199.A O no hydrogen 3.094 N/A GLU 203.A N VAL 177.A O no hydrogen 2.947 N/A ILE 205.A N ILE 179.A O no hydrogen 2.827 N/A ASN 207.A N ARG 183.A O no hydrogen 3.007 N/A SER 208.A N HIS 181.A O no hydrogen 3.037 N/A SER 208.A OG TRP 206.A O no hydrogen 2.865 N/A GLU 209.A N HIS 226.A O no hydrogen 2.908 N/A VAL 211.A N LYS 224.A O no hydrogen 2.849 N/A GLU 212.A N LYS 224.A O no hydrogen 3.341 N/A LEU 213.A N PRO 126.A O no hydrogen 2.916 N/A GLU 214.A N GLY 222.A O no hydrogen 2.915 N/A ASP 216.A N LEU 219.A O no hydrogen 2.984 N/A GLY 217.A N TYR 131.A OH no hydrogen 3.029 N/A ASP 218.A N ASP 216.A OD1 no hydrogen 2.519 N/A LEU 219.A N ASP 216.A OD1 no hydrogen 2.690 N/A LEU 220.A N ASN 134.A O no hydrogen 3.226 N/A ASN 221.A N GLU 214.A O no hydrogen 2.796 N/A GLY 222.A N GLU 214.A O no hydrogen 3.020 N/A ALA 223.A N VAL 236.A O no hydrogen 2.766 N/A LYS 224.A N GLU 212.A O no hydrogen 2.814 N/A ILE 225.A N LYS 234.A O no hydrogen 2.840 N/A HIS 226.A N GLU 209.A O no hydrogen 2.937 N/A ASN 227.A N GLU 232.A O no hydrogen 2.874 N/A LEU 228.A N ASN 207.A O no hydrogen 2.711 N/A VAL 229.A N ASN 227.A OD1 no hydrogen 2.815 N/A SER 230.A N ASN 227.A OD1 no hydrogen 3.050 N/A GLY 231.A N ASN 227.A O no hydrogen 2.799 N/A GLU 232.A N SER 230.A OG no hydrogen 3.215 N/A LYS 234.A N ILE 225.A O no hydrogen 3.032 N/A VAL 236.A N ALA 223.A O no hydrogen 2.809 N/A VAL 238.A N ASN 221.A O no hydrogen 3.098 N/A ALA 239.A N VAL 153.A O no hydrogen 2.746 N/A LEU 241.A N GLY 135.A O no hydrogen 2.866 N/A PHE 242.A N MET 155.A O no hydrogen 2.813 N/A TYR 243.A N SER 137.A O no hydrogen 2.984 N/A TYR 243.A OH GLU 128.A OE1 no hydrogen 2.406 N/A ALA 244.A N VAL 157.A O no hydrogen 2.797 N/A SER 248.A N THR 119.A O.A no hydrogen 2.778 N/A SER 248.A N THR 119.A O.B no hydrogen 2.906 N/A ASN 250.A N GLY 117.A O no hydrogen 2.852 N/A ASN 250.A ND2 THR 119.A OG1.A no hydrogen 3.008 N/A SER 251.A N PRO 249.A O no hydrogen 2.898 N/A SER 251.A OG GLY 264.A O no hydrogen 2.563 N/A LEU 254.A N SER 251.A O no hydrogen 3.029 N/A GLY 255.A N LYS 252.A O no hydrogen 2.894 N/A GLN 257.A N LEU 254.A O no hydrogen 2.912 N/A LYS 259.A N SER 274.A OG no hydrogen 2.976 N/A ALA 261.A N TYR 265.A O no hydrogen 2.780 N/A GLY 264.A N ALA 261.A O no hydrogen 2.911 N/A ILE 266.A N VAL 284.A O no hydrogen 3.010 N/A LEU 267.A N LYS 259.A O no hydrogen 3.100 N/A THR 268.A OG1 GLY 270.A O no hydrogen 2.895 N/A GLU 269.A N LYS 272.A O no hydrogen 2.868 N/A LYS 272.A N GLU 269.A O no hydrogen 3.007 N/A THR 273.A N VAL 278.A O no hydrogen 3.109 N/A THR 273.A OG1 VAL 275.A O no hydrogen 3.385 N/A THR 273.A OG1 VAL 278.A O no hydrogen 2.752 N/A VAL 275.A N THR 273.A OG1 no hydrogen 3.115 N/A VAL 278.A N VAL 275.A O no hydrogen 3.058 N/A PHE 279.A N VAL 112.A O no hydrogen 2.842 N/A ALA 280.A N PRO 271.A O no hydrogen 2.878 N/A CYS 281.A N ILE 114.A O no hydrogen 3.120 N/A CYS 281.A SG ILE 114.A O no hydrogen 4.009 N/A GLY 282.A N SER 298.A OG no hydrogen 3.183 N/A CYS 285.A N GLY 282.A O no hydrogen 2.965 N/A CYS 285.A SG GLY 282.A O no hydrogen 3.567 N/A ASP 286.A N ASP 283.A O no hydrogen 3.389 N/A ARG 287.A NE ASP 263.A OD2 no hydrogen 2.744 N/A ARG 287.A NH2 ASP 263.A OD1 no hydrogen 2.872 N/A ARG 287.A NH2 ASP 263.A OD2 no hydrogen 3.490 N/A VAL 288.A N ASP 286.A OD1 no hydrogen 2.858 N/A TYR 289.A N ASP 286.A OD1 no hydrogen 2.878 N/A TYR 289.A N ASP 286.A OD2 no hydrogen 3.200 N/A ARG 290.A N.A ASP 286.A OD2 no hydrogen 2.678 N/A ARG 290.A N.B ASP 286.A OD2 no hydrogen 2.695 N/A ARG 290.A NH2.B TYR 265.A OH no hydrogen 3.069 N/A ARG 290.A NH2.B ASP 283.A O no hydrogen 3.104 N/A ALA 295.A N GLN 291.A O no hydrogen 2.935 N/A ALA 296.A N ALA 292.A O no hydrogen 2.875 N/A GLY 297.A N ILE 293.A O no hydrogen 3.100 N/A SER 298.A N VAL 294.A O no hydrogen 2.965 N/A GLY 299.A N ALA 295.A O no hydrogen 2.943 N/A GLY 299.A N ALA 296.A O no hydrogen 3.022 N/A CYS 300.A N ALA 296.A O no hydrogen 3.088 N/A MET 301.A N GLY 297.A O no hydrogen 2.922 N/A ALA 302.A N SER 298.A O no hydrogen 2.998 N/A ALA 303.A N GLY 299.A O no hydrogen 2.958 N/A LEU 304.A N CYS 300.A O no hydrogen 2.981 N/A SER 305.A N.A MET 301.A O no hydrogen 2.993 N/A SER 305.A N.B MET 301.A O no hydrogen 2.971 N/A SER 305.A OG.A MET 301.A O no hydrogen 3.221 N/A CYS 306.A N ALA 302.A O no hydrogen 2.814 N/A CYS 306.A SG SER 111.A OG no hydrogen 3.102 N/A GLU 307.A N ALA 303.A O no hydrogen 2.767 N/A LYS 308.A N LEU 304.A O no hydrogen 3.056 N/A TRP 309.A N SER 305.A O.A no hydrogen 2.895 N/A TRP 309.A N SER 305.A O.B no hydrogen 2.853 N/A LEU 310.A N CYS 306.A O no hydrogen 2.891 N/A GLN 311.A N GLU 307.A O no hydrogen 3.138 N/A GLN 311.A N LYS 308.A O no hydrogen 3.056 N/A THR 312.A N TRP 309.A O no hydrogen 3.194 N/A THR 312.A OG1 TRP 309.A O no hydrogen 3.374 N/A THR 312.A OG1 HIS 313.A ND1 no hydrogen 3.070 N/A HIS 313.A N LEU 310.A O no hydrogen 3.197 N/A HIS 313.A ND1 TRP 309.A O no hydrogen 2.715 N/A