Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4a9s_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 7.A N PRO 3.A O no hydrogen 3.227 N/A ASP 8.A N LYS 4.A O no hydrogen 2.938 N/A GLU 9.A N LEU 6.A O no hydrogen 2.983 N/A TYR 10.A N LEU 6.A O no hydrogen 2.863 N/A ILE 11.A N PHE 22.A O no hydrogen 2.883 N/A SER 13.A N LEU 20.A O no hydrogen 2.703 N/A LYS 14.A N SER 13.A OG no hydrogen 2.455 N/A LEU 16.A N VAL 18.A O no hydrogen 2.406 N/A LYS 19.A N ILE 32.A O no hydrogen 3.054 N/A LYS 19.A NZ SER 13.A O no hydrogen 3.353 N/A LYS 19.A NZ THR 15.A OG1 no hydrogen 2.836 N/A LEU 20.A N LYS 14.A O no hydrogen 2.655 N/A ALA 21.A N VAL 30.A O no hydrogen 3.090 N/A PHE 22.A N ILE 11.A O no hydrogen 2.976 N/A GLU 23.A N LYS 28.A O no hydrogen 2.786 N/A ARG 24.A N GLU 9.A O no hydrogen 2.813 N/A ARG 24.A NE ARG 7.A O no hydrogen 2.757 N/A ARG 24.A NH2 ARG 7.A O no hydrogen 2.766 N/A THR 26.A N GLU 23.A O no hydrogen 3.245 N/A CYS 27.A N GLU 23.A O no hydrogen 2.497 N/A CYS 27.A SG ARG 24.A O no hydrogen 3.944 N/A LYS 28.A N THR 26.A OG1 no hydrogen 3.191 N/A VAL 30.A N ALA 21.A O no hydrogen 2.761 N/A ALA 31.A N LEU 73.A O no hydrogen 2.933 N/A ILE 32.A N LYS 19.A O no hydrogen 3.040 N/A LYS 33.A N ILE 71.A O no hydrogen 2.751 N/A LYS 33.A NZ GLU 45.A OE1 no hydrogen 3.497 N/A LYS 33.A NZ GLU 45.A OE2 no hydrogen 2.519 N/A ILE 34.A N GLU 17.A O no hydrogen 2.697 N/A ILE 35.A N TYR 69.A O no hydrogen 2.852 N/A LYS 37.A NZ ASP 65.A OD1 no hydrogen 2.644 N/A LYS 37.A NZ ALA 66.A O no hydrogen 2.554 N/A VAL 42.A N PRO 38.A O no hydrogen 3.413 N/A GLU 43.A N ALA 39.A O no hydrogen 2.544 N/A THR 44.A N LEU 40.A O no hydrogen 2.735 N/A THR 44.A OG1 LEU 40.A O no hydrogen 2.403 N/A GLU 45.A N ASN 41.A O no hydrogen 3.120 N/A ILE 46.A N VAL 42.A O no hydrogen 2.916 N/A GLU 47.A N GLU 43.A O no hydrogen 2.795 N/A ILE 48.A N THR 44.A O no hydrogen 2.814 N/A LEU 49.A N GLU 45.A O no hydrogen 2.883 N/A LYS 50.A N ILE 46.A O no hydrogen 3.230 N/A LYS 51.A N ILE 48.A O no hydrogen 3.229 N/A LEU 52.A N ILE 48.A O no hydrogen 3.297 N/A ASN 53.A N TYR 109.A OH no hydrogen 2.795 N/A CYS 56.A N HIS 54.A ND1 no hydrogen 3.084 N/A CYS 56.A SG GLN 102.A O no hydrogen 3.916 N/A CYS 56.A SG GLN 102.A OE1 no hydrogen 3.763 N/A ILE 57.A N HIS 54.A O no hydrogen 2.974 N/A ILE 58.A N ILE 138.A O no hydrogen 3.090 N/A LYS 59.A N GLU 74.A OE1 no hydrogen 2.914 N/A LYS 61.A N VAL 72.A O no hydrogen 2.878 N/A ASN 62.A N VAL 72.A O no hydrogen 3.513 N/A ASN 62.A ND2 GLU 9.A OE2 no hydrogen 3.544 N/A ASN 62.A ND2 TYR 10.A OH no hydrogen 3.497 N/A PHE 63.A N ASN 62.A OD1 no hydrogen 2.892 N/A PHE 64.A N TYR 70.A O no hydrogen 2.845 N/A ALA 66.A N ASP 68.A O no hydrogen 2.900 N/A TYR 69.A N ILE 35.A O no hydrogen 2.905 N/A TYR 70.A N PHE 64.A O no hydrogen 2.926 N/A ILE 71.A N LYS 33.A O no hydrogen 2.791 N/A VAL 72.A N ASN 62.A O no hydrogen 2.905 N/A LEU 73.A N ALA 31.A O no hydrogen 2.654 N/A GLU 74.A N LYS 59.A O no hydrogen 3.203 N/A GLY 78.A N LEU 127.A O no hydrogen 2.736 N/A GLY 79.A N MET 76.A O no hydrogen 3.274 N/A LEU 81.A N VAL 125.A O no hydrogen 2.780 N/A PHE 82.A N PRO 122.A O no hydrogen 3.088 N/A ASP 83.A N GLU 80.A O no hydrogen 3.102 N/A LYS 84.A N LEU 81.A O no hydrogen 2.936 N/A VAL 85.A N PHE 82.A O no hydrogen 3.131 N/A VAL 86.A N PHE 82.A O no hydrogen 2.977 N/A ARG 90.A NE LEU 191.A O no hydrogen 3.421 N/A ARG 90.A NH1 VAL 221.A O no hydrogen 3.352 N/A ARG 90.A NH2 LEU 191.A O no hydrogen 2.875 N/A ARG 90.A NH2 VAL 221.A O no hydrogen 3.105 N/A LYS 92.A NZ GLU 132.A OE1 no hydrogen 3.569 N/A LYS 92.A NZ GLU 132.A OE2 no hydrogen 2.922 N/A THR 95.A OG1 GLU 132.A OE1 no hydrogen 3.017 N/A CYS 96.A N LYS 92.A O no hydrogen 3.075 N/A CYS 96.A SG LEU 91.A O no hydrogen 3.678 N/A CYS 96.A SG LYS 92.A O no hydrogen 3.612 N/A LYS 97.A N GLU 93.A O no hydrogen 2.910 N/A LYS 97.A NZ TRP 255.A O no hydrogen 3.112 N/A LYS 97.A NZ ASP 258.A OD2 no hydrogen 2.638 N/A LEU 98.A N ALA 94.A O no hydrogen 3.133 N/A TYR 99.A N THR 95.A O no hydrogen 3.120 N/A TYR 99.A OH GLU 132.A O no hydrogen 2.635 N/A PHE 100.A N CYS 96.A O no hydrogen 2.891 N/A TYR 101.A N LYS 97.A O no hydrogen 2.856 N/A GLN 102.A NE2 LEU 98.A O no hydrogen 3.144 N/A GLN 102.A NE2 CYS 134.A O no hydrogen 3.248 N/A MET 103.A N TYR 99.A O no hydrogen 2.928 N/A LEU 104.A N PHE 100.A O no hydrogen 2.805 N/A LEU 105.A N TYR 101.A O no hydrogen 3.115 N/A ALA 106.A N GLN 102.A O no hydrogen 3.022 N/A VAL 107.A N MET 103.A O no hydrogen 3.000 N/A GLN 108.A N LEU 104.A O no hydrogen 2.701 N/A GLN 108.A NE2 GLU 248.A OE2 no hydrogen 2.738 N/A TYR 109.A N LEU 105.A O no hydrogen 3.024 N/A LEU 110.A N ALA 106.A O no hydrogen 2.898 N/A HIS 111.A N VAL 107.A O no hydrogen 2.896 N/A HIS 111.A NE2 ASP 179.A OD2 no hydrogen 2.819 N/A GLU 112.A N GLN 108.A O no hydrogen 2.737 N/A ASN 113.A N TYR 109.A O no hydrogen 3.125 N/A ASN 113.A N LEU 110.A O no hydrogen 2.914 N/A ASN 113.A ND2 TYR 109.A O no hydrogen 2.951 N/A GLY 114.A N HIS 111.A O no hydrogen 3.047 N/A ILE 115.A N LEU 110.A O no hydrogen 3.042 N/A ILE 116.A N LYS 145.A O no hydrogen 2.896 N/A HIS 117.A N ASP 179.A OD2 no hydrogen 2.892 N/A HIS 117.A NE2 THR 139.A O no hydrogen 3.049 N/A ARG 118.A N ASP 179.A OD1 no hydrogen 2.867 N/A ARG 118.A NE HIS 143.A O no hydrogen 3.004 N/A ARG 118.A NH2 HIS 143.A O no hydrogen 3.306 N/A ASP 119.A N HIS 117.A ND1 no hydrogen 2.953 N/A ASN 124.A N LYS 121.A O no hydrogen 2.699 N/A ASN 124.A ND2 ASP 119.A O no hydrogen 2.671 N/A ASN 124.A ND2 ASP 119.A OD2 no hydrogen 3.526 N/A VAL 125.A N PRO 122.A O no hydrogen 3.350 N/A LEU 126.A N LYS 137.A O no hydrogen 2.813 N/A LEU 127.A N GLY 79.A O no hydrogen 2.858 N/A SER 128.A N LEU 135.A O no hydrogen 2.690 N/A SER 128.A OG LEU 135.A O no hydrogen 3.161 N/A GLU 131.A N SER 129.A OG no hydrogen 2.798 N/A CYS 134.A SG TYR 99.A OH no hydrogen 3.800 N/A CYS 134.A SG SER 129.A O no hydrogen 4.012 N/A CYS 134.A SG GLU 131.A O no hydrogen 3.546 N/A CYS 134.A SG LEU 135.A O no hydrogen 3.896 N/A LEU 135.A N SER 128.A OG no hydrogen 2.941 N/A ILE 136.A N GLN 102.A OE1 no hydrogen 2.949 N/A LYS 137.A N LEU 126.A O no hydrogen 2.873 N/A LYS 137.A NZ PRO 55.A O no hydrogen 2.604 N/A LYS 137.A NZ GLU 272.A OE2 no hydrogen 3.208 N/A ILE 138.A N CYS 56.A O no hydrogen 2.898 N/A THR 139.A N ASN 124.A O no hydrogen 3.022 N/A PHE 141.A N GLU 45.A OE2 no hydrogen 3.308 N/A SER 144.A N PHE 141.A O no hydrogen 3.265 N/A SER 144.A OG HIS 117.A O no hydrogen 3.437 N/A SER 144.A OG PHE 141.A O no hydrogen 3.437 N/A LYS 145.A N ILE 116.A O no hydrogen 2.927 N/A LEU 147.A N GLY 114.A O no hydrogen 2.820 N/A THR 153.A N SER 149.A O no hydrogen 2.696 N/A THR 153.A OG1 LEU 150.A O no hydrogen 2.586 N/A LEU 154.A N LEU 150.A O no hydrogen 2.887 N/A CYS 155.A SG MET 151.A O no hydrogen 3.653 N/A GLY 156.A N THR 153.A O no hydrogen 3.226 N/A THR 157.A OG1 THR 159.A OG1 no hydrogen 3.342 N/A THR 159.A OG1 THR 157.A OG1 no hydrogen 3.342 N/A LEU 161.A N PRO 158.A O no hydrogen 2.948 N/A GLU 164.A N GLU 164.A OE1 no hydrogen 2.800 N/A VAL 165.A N ALA 162.A O no hydrogen 3.246 N/A VAL 167.A N PRO 163.A O no hydrogen 2.965 N/A SER 168.A N GLU 164.A O no hydrogen 3.091 N/A SER 168.A OG VAL 165.A O no hydrogen 2.598 N/A VAL 169.A N LEU 166.A O no hydrogen 3.049 N/A GLY 170.A N VAL 167.A O no hydrogen 2.938 N/A THR 171.A N SER 168.A O no hydrogen 3.149 N/A THR 171.A OG1 SER 168.A O no hydrogen 3.493 N/A ALA 172.A N VAL 169.A O no hydrogen 3.366 N/A ALA 177.A N TYR 174.A O no hydrogen 3.050 N/A VAL 178.A N ASN 175.A O no hydrogen 3.133 N/A ASP 179.A N ARG 176.A O no hydrogen 3.112 N/A CYS 180.A N ALA 177.A O no hydrogen 3.036 N/A CYS 180.A SG PHE 245.A O no hydrogen 3.600 N/A TRP 181.A N ALA 177.A O no hydrogen 3.156 N/A SER 182.A N VAL 178.A O no hydrogen 3.175 N/A SER 182.A OG VAL 178.A O no hydrogen 3.144 N/A LEU 183.A N ASP 179.A O no hydrogen 2.970 N/A GLY 184.A N CYS 180.A O no hydrogen 3.130 N/A VAL 185.A N TRP 181.A O no hydrogen 3.043 N/A ILE 186.A N SER 182.A O no hydrogen 2.974 N/A LEU 187.A N LEU 183.A O no hydrogen 2.890 N/A PHE 188.A N GLY 184.A O no hydrogen 2.910 N/A ILE 189.A N VAL 185.A O no hydrogen 3.102 N/A CYS 190.A N ILE 186.A O no hydrogen 2.874 N/A CYS 190.A SG ILE 186.A O no hydrogen 3.427 N/A LEU 191.A N LEU 187.A O no hydrogen 2.931 N/A SER 192.A N PHE 188.A O no hydrogen 3.049 N/A SER 192.A N ILE 189.A O no hydrogen 3.262 N/A SER 192.A OG PHE 188.A O no hydrogen 2.744 N/A GLY 193.A N ILE 189.A O no hydrogen 2.600 N/A TYR 194.A N SER 192.A OG no hydrogen 3.314 N/A TYR 194.A OH ASN 216.A O no hydrogen 2.826 N/A SER 198.A N GLN 209.A OE1 no hydrogen 3.251 N/A HIS 200.A N SER 198.A OG no hydrogen 2.805 N/A THR 202.A OG1 VAL 204.A O no hydrogen 3.569 N/A VAL 204.A N THR 202.A OG1 no hydrogen 3.176 N/A ASP 208.A N SER 205.A OG no hydrogen 3.303 N/A GLN 209.A N SER 205.A O no hydrogen 2.890 N/A GLN 209.A NE2 SER 198.A O no hydrogen 2.697 N/A GLN 209.A NE2 VAL 204.A O no hydrogen 3.118 N/A ILE 210.A N LEU 206.A O no hydrogen 3.012 N/A THR 211.A N LYS 207.A O no hydrogen 2.915 N/A THR 211.A OG1 LYS 207.A O no hydrogen 3.019 N/A THR 211.A OG1 ASP 208.A O no hydrogen 3.332 N/A SER 212.A N ASP 208.A O no hydrogen 3.072 N/A SER 212.A OG ASP 208.A O no hydrogen 2.944 N/A SER 212.A OG GLN 209.A O no hydrogen 3.095 N/A GLY 213.A N ILE 210.A O no hydrogen 3.063 N/A LYS 214.A N SER 212.A OG no hydrogen 3.335 N/A TYR 215.A N GLY 213.A O no hydrogen 3.079 N/A ASN 216.A N PRO 196.A O no hydrogen 2.834 N/A ILE 218.A N TYR 194.A OH no hydrogen 3.016 N/A GLU 220.A N GLU 220.A OE1 no hydrogen 2.533 N/A VAL 221.A N ILE 218.A O no hydrogen 2.932 N/A TRP 222.A N ILE 218.A O no hydrogen 3.134 N/A TRP 222.A NE1 TYR 194.A OH no hydrogen 3.047 N/A ALA 223.A N PRO 219.A O no hydrogen 2.704 N/A VAL 225.A N TRP 222.A O no hydrogen 2.830 N/A SER 226.A N GLU 93.A OE1 no hydrogen 3.146 N/A SER 226.A OG GLU 93.A OE1 no hydrogen 3.448 N/A SER 226.A OG GLU 93.A OE2 no hydrogen 2.434 N/A ALA 229.A N SER 226.A OG no hydrogen 3.238 N/A LEU 230.A N SER 226.A O no hydrogen 3.314 N/A ASP 231.A N GLU 227.A O no hydrogen 2.994 N/A LEU 232.A N LYS 228.A O no hydrogen 3.165 N/A VAL 233.A N ALA 229.A O no hydrogen 3.324 N/A LYS 234.A N LEU 230.A O no hydrogen 2.921 N/A LYS 235.A N ASP 231.A O no hydrogen 3.060 N/A LYS 235.A N LEU 232.A O no hydrogen 3.115 N/A LYS 235.A NZ ASP 231.A OD2 no hydrogen 2.771 N/A LEU 236.A N LEU 232.A O no hydrogen 3.110 N/A LEU 236.A N VAL 233.A O no hydrogen 3.047 N/A LEU 237.A N VAL 233.A O no hydrogen 2.879 N/A LYS 242.A N ASP 240.A OD1 no hydrogen 3.145 N/A ALA 243.A N ASP 240.A O no hydrogen 3.070 N/A ARG 244.A N ASP 240.A O no hydrogen 2.897 N/A ARG 244.A NE VAL 238.A O no hydrogen 2.860 N/A ARG 244.A NH1 ALA 177.A O no hydrogen 2.695 N/A ARG 244.A NH2 VAL 238.A O no hydrogen 3.310 N/A ARG 244.A NH2 VAL 239.A O no hydrogen 3.424 N/A PHE 245.A N LYS 235.A O no hydrogen 3.230 N/A THR 246.A N GLU 249.A OE1 no hydrogen 2.906 N/A THR 246.A OG1 GLU 248.A OE1 no hydrogen 3.216 N/A THR 246.A OG1 GLU 249.A OE1 no hydrogen 3.533 N/A THR 247.A OG1 GLU 248.A OE2 no hydrogen 3.360 N/A GLU 249.A N THR 246.A OG1 no hydrogen 3.247 N/A ALA 250.A N THR 246.A O no hydrogen 2.870 N/A LEU 251.A N THR 247.A O no hydrogen 2.854 N/A ARG 252.A N GLU 249.A O no hydrogen 3.260 N/A HIS 253.A N ALA 250.A O no hydrogen 2.924 N/A HIS 253.A NE2 ASP 231.A OD2 no hydrogen 2.836 N/A TRP 255.A N HIS 253.A ND1 no hydrogen 2.794 N/A TRP 255.A NE1 GLU 93.A OE2 no hydrogen 2.919 N/A LEU 256.A N HIS 253.A O no hydrogen 2.991 N/A GLN 257.A N PRO 254.A O no hydrogen 3.275 N/A GLN 257.A NE2 LEU 251.A O no hydrogen 2.983 N/A GLN 257.A NE2 HIS 253.A O no hydrogen 2.831 N/A ASP 260.A N ASP 258.A OD1 no hydrogen 3.243 N/A MET 261.A N ASP 258.A OD1 no hydrogen 3.377 N/A LYS 262.A N ASP 258.A O no hydrogen 3.221 N/A ARG 263.A N GLU 259.A O no hydrogen 3.228 N/A ARG 263.A NH1 ASP 260.A OD1 no hydrogen 2.278 N/A LYS 264.A N ASP 260.A O no hydrogen 2.932 N/A PHE 265.A N MET 261.A O no hydrogen 3.019 N/A GLN 266.A N LYS 262.A O no hydrogen 2.947 N/A ASP 267.A N ARG 263.A O no hydrogen 2.954 N/A LEU 268.A N LYS 264.A O no hydrogen 3.140 N/A LEU 269.A N PHE 265.A O no hydrogen 2.854 N/A SER 270.A N GLN 266.A O no hydrogen 2.776 N/A SER 270.A OG GLN 266.A O no hydrogen 3.122 N/A GLU 271.A N ASP 267.A O no hydrogen 2.882 N/A GLU 272.A N LEU 268.A O no hydrogen 3.153 N/A ASN 273.A N LEU 269.A O no hydrogen 3.025 N/A GLU 274.A N SER 270.A O no hydrogen 2.895 N/A THR 276.A N ASN 273.A O no hydrogen 2.911 N/A THR 276.A OG1 ASN 273.A O no hydrogen 3.246 N/A