Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4ad9_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 3.A N GLU 169.A OE1 no hydrogen 3.417 N/A GLU 9.A N ARG 17.A O no hydrogen 2.950 N/A LEU 11.A N VAL 15.A O no hydrogen 2.897 N/A SER 12.A N VAL 15.A O no hydrogen 3.143 N/A SER 12.A OG GLU 157.A OE1 no hydrogen 3.349 N/A SER 12.A OG GLU 157.A OE2 no hydrogen 2.560 N/A ARG 14.A N SER 12.A OG no hydrogen 3.297 N/A ARG 14.A NE GLY 134.A O no hydrogen 2.757 N/A VAL 15.A N SER 12.A OG no hydrogen 3.065 N/A VAL 16.A N LEU 35.A O no hydrogen 3.028 N/A ARG 17.A N GLU 9.A O no hydrogen 2.665 N/A VAL 18.A N THR 33.A O no hydrogen 2.813 N/A LEU 19.A N ARG 7.A O no hydrogen 2.825 N/A GLY 20.A N THR 31.A O no hydrogen 2.714 N/A CYS 21.A SG LEU 19.A O no hydrogen 3.334 N/A ASN 22.A ND2 THR 31.A OG1 no hydrogen 2.790 N/A ASN 22.A ND2 GLU 49.A OE2 no hydrogen 2.908 N/A GLY 24.A N LEU 28.A O no hydrogen 3.075 N/A THR 27.A OG1 ASN 22.A O no hydrogen 2.599 N/A GLN 29.A N GLN 29.A OE1 no hydrogen 2.878 N/A GLN 29.A NE2 ALA 3.A O no hydrogen 2.954 N/A GLY 30.A N THR 27.A O no hydrogen 2.987 N/A THR 31.A N ASN 22.A OD1 no hydrogen 2.766 N/A THR 31.A OG1 ASP 81.A O no hydrogen 2.723 N/A ASN 32.A N GLY 198.A O no hydrogen 2.848 N/A ASN 32.A ND2 PRO 197.A O no hydrogen 3.110 N/A ASN 32.A ND2 GLY 200.A O no hydrogen 2.760 N/A THR 33.A N VAL 18.A O no hydrogen 3.096 N/A THR 33.A OG1 VAL 18.A O no hydrogen 2.804 N/A THR 33.A OG1 TYR 55.A OH no hydrogen 2.715 N/A TYR 34.A N ILE 45.A O no hydrogen 2.975 N/A TYR 34.A OH PRO 197.A O no hydrogen 2.558 N/A LEU 35.A N VAL 16.A O no hydrogen 2.780 N/A VAL 36.A N ILE 43.A O no hydrogen 2.821 N/A GLY 37.A N ARG 14.A O no hydrogen 2.929 N/A THR 38.A N GLU 133.A O no hydrogen 2.859 N/A THR 38.A OG1 GLU 133.A O no hydrogen 3.310 N/A ARG 42.A N ALA 69.A O no hydrogen 2.788 N/A ARG 42.A NE GLY 39.A O no hydrogen 2.885 N/A ARG 42.A NH2 GLY 39.A O no hydrogen 3.498 N/A ILE 43.A N VAL 36.A O no hydrogen 2.894 N/A LEU 44.A N GLU 72.A O no hydrogen 2.931 N/A ILE 45.A N TYR 34.A O no hydrogen 2.796 N/A ASP 46.A N VAL 74.A O no hydrogen 2.847 N/A THR 47.A N HIS 82.A O no hydrogen 2.977 N/A THR 47.A OG1 HIS 82.A O no hydrogen 2.791 N/A TYR 55.A N ILE 52.A O no hydrogen 3.300 N/A TYR 55.A OH THR 33.A OG1 no hydrogen 2.715 N/A SER 57.A N PRO 53.A O no hydrogen 3.390 N/A SER 57.A OG PRO 53.A O no hydrogen 3.446 N/A CYS 58.A N GLU 54.A O no hydrogen 3.128 N/A CYS 58.A SG GLU 54.A O no hydrogen 3.465 N/A LEU 59.A N TYR 55.A O no hydrogen 2.782 N/A LYS 60.A N ILE 56.A O no hydrogen 2.902 N/A GLN 61.A N SER 57.A O no hydrogen 2.962 N/A ALA 62.A N CYS 58.A O no hydrogen 2.968 N/A LEU 63.A N LEU 59.A O no hydrogen 3.042 N/A THR 64.A N LYS 60.A O no hydrogen 3.080 N/A THR 64.A OG1 LYS 60.A O no hydrogen 2.821 N/A GLU 65.A N GLN 61.A O no hydrogen 2.767 N/A PHE 66.A N ALA 62.A O no hydrogen 2.801 N/A ASN 67.A N THR 64.A O no hydrogen 3.131 N/A THR 68.A N LEU 63.A O no hydrogen 2.813 N/A THR 68.A OG1 GLY 39.A O no hydrogen 3.000 N/A THR 68.A OG1 ALA 69.A O no hydrogen 3.472 N/A ALA 69.A N THR 68.A OG1 no hydrogen 2.853 N/A GLN 71.A N ARG 42.A O no hydrogen 2.696 N/A GLN 71.A NE2 GLU 72.A OE2 no hydrogen 2.804 N/A GLN 71.A NE2 LYS 131.A O no hydrogen 2.980 N/A ILE 73.A N CYS 100.A O no hydrogen 2.882 N/A VAL 74.A N LEU 44.A O no hydrogen 2.852 N/A VAL 75.A N LYS 102.A O no hydrogen 2.995 N/A THR 76.A N ASP 46.A OD1 no hydrogen 2.955 N/A THR 76.A OG1 ASP 46.A OD1 no hydrogen 3.002 N/A THR 76.A OG1 ASP 46.A OD2 no hydrogen 3.056 N/A THR 76.A OG1 HIS 77.A ND1 no hydrogen 3.084 N/A HIS 77.A ND1 THR 76.A OG1 no hydrogen 3.084 N/A TRP 78.A N ASP 148.A OD2 no hydrogen 2.934 N/A HIS 82.A N HIS 79.A O no hydrogen 2.909 N/A HIS 82.A ND1 ASP 46.A OD2 no hydrogen 2.715 N/A SER 83.A N HIS 79.A O no hydrogen 3.204 N/A SER 83.A OG TRP 78.A O no hydrogen 2.892 N/A SER 83.A OG HIS 79.A O no hydrogen 3.120 N/A GLY 84.A N GLY 48.A O no hydrogen 3.156 N/A GLY 84.A N ARG 80.A O no hydrogen 3.015 N/A ILE 89.A N GLY 85.A O no hydrogen 2.971 N/A CYS 90.A N ILE 86.A O no hydrogen 3.181 N/A CYS 90.A SG ILE 86.A O no hydrogen 3.335 N/A CYS 90.A SG GLN 119.A OE1 no hydrogen 3.567 N/A LYS 91.A N GLY 87.A O no hydrogen 3.157 N/A SER 92.A N ASP 88.A O no hydrogen 2.994 N/A ILE 93.A N ILE 89.A O no hydrogen 2.804 N/A ASN 95.A ND2 THR 97.A O no hydrogen 2.967 N/A TYR 99.A OH ILE 93.A O no hydrogen 2.702 N/A LYS 102.A N ILE 73.A O no hydrogen 2.768 N/A LYS 102.A NZ GLU 72.A OE1 no hydrogen 2.924 N/A LYS 103.A N VAL 122.A O no hydrogen 3.178 N/A LYS 103.A NZ LEU 104.A O no hydrogen 2.791 N/A LYS 103.A NZ GLU 112.A OE1 no hydrogen 2.861 N/A LYS 103.A NZ GLU 112.A OE2 no hydrogen 3.348 N/A LYS 103.A NZ ASP 148.A OD2 no hydrogen 2.648 N/A ARG 106.A NE ASP 147.A OD1 no hydrogen 2.867 N/A ARG 106.A NH2 ASP 147.A OD2 no hydrogen 3.240 N/A ASN 107.A N ASP 147.A OD1 no hydrogen 2.975 N/A ASN 107.A ND2 TYR 141.A OH no hydrogen 3.465 N/A GLY 117.A N ILE 114.A O no hydrogen 3.001 N/A VAL 122.A N ILE 101.A O no hydrogen 2.796 N/A TYR 123.A OH GLU 112.A OE1 no hydrogen 2.842 N/A LEU 124.A N LYS 103.A O no hydrogen 2.945 N/A LYS 125.A N ASP 128.A OD2 no hydrogen 2.971 N/A GLY 127.A N VAL 139.A O no hydrogen 2.791 N/A ASP 128.A N LYS 125.A O no hydrogen 3.083 N/A ILE 130.A N LEU 137.A O no hydrogen 2.754 N/A THR 132.A N ALA 135.A O no hydrogen 2.927 N/A THR 132.A OG1 GLN 71.A OE1 no hydrogen 2.661 N/A ALA 135.A N THR 132.A O no hydrogen 3.255 N/A THR 136.A N GLU 156.A OE1 no hydrogen 2.807 N/A THR 136.A OG1 GLU 156.A OE2 no hydrogen 2.981 N/A LEU 137.A N ILE 130.A O no hydrogen 2.787 N/A ARG 138.A N LEU 153.A O no hydrogen 2.832 N/A VAL 139.A N ASP 128.A O no hydrogen 2.750 N/A LEU 140.A N ALA 151.A O no hydrogen 2.810 N/A TYR 141.A N ASP 126.A OD1 no hydrogen 2.631 N/A TYR 141.A OH ASP 147.A O no hydrogen 2.661 N/A THR 142.A N HIS 149.A O no hydrogen 2.727 N/A THR 142.A OG1 HIS 149.A ND1 no hydrogen 2.830 N/A THR 142.A OG1 HIS 149.A O no hydrogen 3.343 N/A HIS 145.A ND1 VAL 173.A O no hydrogen 2.699 N/A HIS 145.A NE2 HIS 79.A ND1 no hydrogen 3.094 N/A THR 146.A OG1 ASP 148.A OD1 no hydrogen 2.820 N/A HIS 149.A N THR 146.A O no hydrogen 3.432 N/A HIS 149.A ND1 THR 142.A OG1 no hydrogen 2.830 N/A MET 150.A N THR 76.A O no hydrogen 2.937 N/A ALA 151.A N LEU 140.A O no hydrogen 2.949 N/A LEU 152.A N PHE 161.A O no hydrogen 2.971 N/A LEU 153.A N ARG 138.A O no hydrogen 2.835 N/A LEU 154.A N ALA 159.A O no hydrogen 2.762 N/A GLU 155.A N THR 136.A O no hydrogen 3.013 N/A GLU 156.A N GLU 156.A OE1 no hydrogen 2.807 N/A GLU 157.A N LEU 154.A O no hydrogen 3.370 N/A ASN 158.A ND2 LYS 191.A O no hydrogen 2.958 N/A ASN 158.A ND2 ASP 193.A OD2 no hydrogen 3.180 N/A ALA 159.A N LEU 154.A O no hydrogen 3.132 N/A ILE 160.A N ILE 194.A O no hydrogen 3.036 N/A PHE 161.A N LEU 152.A O no hydrogen 2.848 N/A SER 162.A N TYR 196.A O no hydrogen 3.125 N/A SER 162.A OG ILE 166.A O no hydrogen 2.769 N/A ASP 164.A N HIS 149.A NE2 no hydrogen 3.132 N/A CYS 165.A N SER 162.A O no hydrogen 3.182 N/A LEU 167.A N TYR 213.A OH no hydrogen 3.032 N/A GLY 168.A N HIS 199.A O no hydrogen 2.902 N/A THR 172.A OG1 ASP 164.A O no hydrogen 2.752 N/A THR 172.A OG1 VAL 173.A O no hydrogen 3.501 N/A GLU 175.A N GLY 144.A O no hydrogen 2.882 N/A ASP 176.A N GLY 144.A O no hydrogen 3.133 N/A ASP 179.A N ASP 176.A OD2 no hydrogen 2.907 N/A TYR 180.A N ASP 176.A O no hydrogen 3.031 N/A TYR 180.A OH CYS 165.A O no hydrogen 3.135 N/A MET 181.A N LEU 177.A O no hydrogen 2.902 N/A ASN 182.A N TYR 178.A O no hydrogen 3.230 N/A SER 183.A N ASP 179.A O no hydrogen 2.912 N/A SER 183.A OG PRO 143.A O no hydrogen 2.712 N/A SER 183.A OG ASP 179.A O no hydrogen 2.916 N/A LEU 184.A N TYR 180.A O no hydrogen 2.998 N/A LYS 185.A N MET 181.A O no hydrogen 3.108 N/A GLU 186.A N ASN 182.A O no hydrogen 3.049 N/A LEU 187.A N SER 183.A O no hydrogen 2.837 N/A LEU 188.A N LEU 184.A O no hydrogen 3.089 N/A LYS 189.A N GLU 186.A O no hydrogen 3.070 N/A ILE 190.A N LEU 187.A O no hydrogen 3.213 N/A ASP 193.A N ASN 158.A O no hydrogen 2.807 N/A ILE 195.A N ILE 203.A O no hydrogen 2.860 N/A TYR 196.A N ILE 160.A O no hydrogen 2.741 N/A TYR 196.A OH GLU 157.A OE1 no hydrogen 2.787 N/A GLY 198.A N GLY 163.A O no hydrogen 2.756 N/A HIS 199.A ND1 GLY 30.A O no hydrogen 2.947 N/A HIS 199.A NE2 ASP 81.A OD2 no hydrogen 3.084 N/A ILE 203.A N ILE 195.A O no hydrogen 2.902 N/A LYS 209.A N ASN 205.A O no hydrogen 3.102 N/A LYS 209.A NZ GLY 168.A O no hydrogen 3.554 N/A ILE 210.A N ALA 206.A O no hydrogen 3.006 N/A GLN 211.A N GLU 207.A O no hydrogen 2.997 N/A GLN 211.A NE2 GLU 207.A OE2 no hydrogen 3.162 N/A GLN 212.A N ALA 208.A O no hydrogen 2.945 N/A TYR 213.A N LYS 209.A O no hydrogen 2.996 N/A TYR 213.A OH GLY 170.A O no hydrogen 2.902 N/A ILE 214.A N ILE 210.A O no hydrogen 2.975 N/A SER 215.A N GLN 211.A O no hydrogen 2.994 N/A HIS 216.A N GLN 212.A O no hydrogen 3.106 N/A ASN 218.A N ILE 214.A O no hydrogen 2.963 N/A ILE 219.A N SER 215.A O no hydrogen 2.926 N/A ARG 220.A NH1 GLN 223.A OE1 no hydrogen 2.733 N/A GLU 221.A N ARG 217.A O no hydrogen 3.081 N/A GLN 222.A N ASN 218.A O no hydrogen 2.905 N/A GLN 223.A N ILE 219.A O no hydrogen 3.065 N/A GLN 223.A NE2 ILE 245.A O no hydrogen 3.091 N/A ILE 224.A N ARG 220.A O no hydrogen 3.114 N/A LEU 225.A N GLU 221.A O no hydrogen 2.991 N/A THR 226.A N GLN 222.A O no hydrogen 3.009 N/A THR 226.A OG1 GLN 222.A O no hydrogen 2.675 N/A LEU 227.A N GLN 223.A O no hydrogen 3.255 N/A PHE 228.A N ILE 224.A O no hydrogen 3.250 N/A ARG 229.A N LEU 225.A O no hydrogen 2.762 N/A GLU 230.A N THR 226.A O no hydrogen 2.880 N/A ASN 231.A N LEU 227.A O no hydrogen 3.141 N/A ASN 231.A ND2 LEU 227.A O no hydrogen 2.664 N/A LYS 234.A N ASN 231.A O no hydrogen 3.074 N/A PHE 236.A N TRP 284.A O no hydrogen 2.782 N/A LEU 241.A N THR 237.A O no hydrogen 3.056 N/A VAL 242.A N VAL 238.A O no hydrogen 2.843 N/A LYS 243.A N MET 239.A O no hydrogen 3.260 N/A ILE 244.A N GLU 240.A O no hydrogen 3.296 N/A ILE 245.A N LEU 241.A O no hydrogen 2.860 N/A TYR 246.A N VAL 242.A O no hydrogen 3.056 N/A TYR 246.A OH ASN 260.A OD1 no hydrogen 2.687 N/A LEU 253.A N PRO 250.A O no hydrogen 3.015 N/A HIS 254.A N GLU 251.A O no hydrogen 3.268 N/A ALA 257.A N LEU 253.A O no hydrogen 3.020 N/A LYS 258.A N HIS 254.A O no hydrogen 2.961 N/A HIS 259.A N GLU 255.A O no hydrogen 3.096 N/A ASN 260.A N MET 256.A O no hydrogen 2.910 N/A LEU 261.A N ALA 257.A O no hydrogen 2.842 N/A LEU 262.A N LYS 258.A O no hydrogen 3.167 N/A LEU 263.A N HIS 259.A O no hydrogen 3.148 N/A HIS 264.A N ASN 260.A O no hydrogen 3.117 N/A LEU 265.A N LEU 261.A O no hydrogen 2.852 N/A LYS 266.A N LEU 262.A O no hydrogen 2.996 N/A LYS 267.A N LEU 263.A O no hydrogen 3.322 N/A LYS 267.A NZ GLU 221.A OE1 no hydrogen 3.027 N/A LYS 267.A NZ GLU 271.A OE1 no hydrogen 3.431 N/A LYS 267.A NZ GLU 271.A OE2 no hydrogen 2.643 N/A LEU 268.A N HIS 264.A O no hydrogen 3.202 N/A GLU 269.A N LEU 265.A O no hydrogen 2.957 N/A LYS 270.A N LYS 266.A O no hydrogen 3.027 N/A LYS 270.A NZ ASP 176.A OD1 no hydrogen 2.921 N/A LYS 270.A NZ ASP 176.A OD2 no hydrogen 2.803 N/A GLU 271.A N LYS 267.A O no hydrogen 3.066 N/A GLY 272.A N GLU 269.A O no hydrogen 3.096 N/A LYS 273.A N LEU 268.A O no hydrogen 2.882 N/A LYS 273.A NZ GLU 271.A OE1 no hydrogen 3.327 N/A ILE 274.A N LEU 268.A O no hydrogen 3.358 N/A PHE 275.A N LYS 285.A O no hydrogen 3.325 N/A SER 276.A OG GLU 269.A OE2 no hydrogen 2.966 N/A ASN 277.A N LYS 283.A O no hydrogen 3.159 N/A ASP 279.A N ASN 277.A OD1 no hydrogen 3.355 N/A LYS 282.A NZ ASN 277.A O no hydrogen 2.904 N/A LYS 283.A N ASN 277.A OD1 no hydrogen 2.714 N/A TRP 284.A N PHE 236.A O no hydrogen 2.817 N/A TRP 284.A NE1 GLU 269.A OE1 no hydrogen 3.013 N/A LYS 285.A N PHE 275.A O no hydrogen 3.115 N/A LYS 285.A NZ PHE 232.A O no hydrogen 3.045 N/A LYS 285.A NZ ALA 286.A O no hydrogen 2.944 N/A LEU 288.A N HIS 287.A ND1 no hydrogen 3.206 N/A