Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4anf_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLY 7.A N THR 339.A O no hydrogen 3.001 N/A ARG 8.A N LEU 5.A O no hydrogen 2.863 N/A ARG 8.A NH2 ASN 15.A O no hydrogen 3.160 N/A SER 12.A N ASP 11.A OD1 no hydrogen 2.901 N/A SER 12.A OG GLU 136.A OE1 no hydrogen 2.581 N/A LEU 13.A N GLU 136.A OE2 no hydrogen 2.783 N/A LEU 14.A N SER 12.A OG no hydrogen 3.099 N/A ASN 15.A N SER 12.A O no hydrogen 2.916 N/A ASN 15.A ND2 ASP 11.A OD1 no hydrogen 3.032 N/A PHE 16.A N LEU 13.A O no hydrogen 3.031 N/A THR 17.A N GLU 20.A OE1 no hydrogen 3.049 N/A GLU 20.A N THR 17.A OG1 no hydrogen 2.803 N/A VAL 21.A N THR 17.A O no hydrogen 3.121 N/A GLN 22.A N THR 18.A O no hydrogen 2.951 N/A GLN 22.A NE2 PHE 180.A O no hydrogen 3.239 N/A GLN 22.A NE2 ASN 181.A OD1 no hydrogen 3.028 N/A HIS 23.A N GLU 19.A O no hydrogen 3.173 N/A LEU 24.A N GLU 20.A O no hydrogen 3.081 N/A ILE 25.A N VAL 21.A O no hydrogen 2.952 N/A ASP 26.A N GLN 22.A O no hydrogen 2.622 N/A LEU 27.A N HIS 23.A O no hydrogen 2.702 N/A SER 28.A N LEU 24.A O no hydrogen 3.042 N/A SER 28.A OG LEU 24.A O no hydrogen 2.865 N/A ILE 29.A N ILE 25.A O no hydrogen 3.407 N/A ASP 30.A N ASP 26.A O no hydrogen 3.094 N/A LEU 31.A N LEU 27.A O no hydrogen 2.851 N/A LYS 32.A N SER 28.A O no hydrogen 2.976 N/A LYS 32.A NZ GLU 150.A OE1 no hydrogen 3.378 N/A LYS 32.A NZ GLU 150.A OE2 no hydrogen 2.727 N/A LYS 32.A NZ ASN 327.A OD1 no hydrogen 2.914 N/A LYS 33.A N ILE 29.A O no hydrogen 2.931 N/A ALA 34.A N ASP 30.A O no hydrogen 2.982 N/A LYS 35.A N LEU 31.A O no hydrogen 3.108 N/A LYS 35.A NZ ASP 72.A OD2 no hydrogen 2.780 N/A TYR 36.A N LYS 32.A O no hydrogen 3.463 N/A TYR 36.A OH GLU 326.A OE2 no hydrogen 2.852 N/A GLN 37.A N ALA 34.A O no hydrogen 3.019 N/A GLY 38.A N LYS 35.A O no hydrogen 2.596 N/A LEU 39.A N ALA 34.A O no hydrogen 3.039 N/A ILE 41.A N GLY 38.A O no hydrogen 3.125 N/A ASN 43.A ND2 LEU 39.A O no hydrogen 2.838 N/A ARG 44.A NH1 HIS 40.A O no hydrogen 3.485 N/A ARG 44.A NH2 SER 71.A O no hydrogen 3.022 N/A LEU 46.A N LEU 73.A O no hydrogen 2.852 N/A VAL 47.A N ARG 44.A O no hydrogen 3.458 N/A LYS 49.A N LEU 46.A O no hydrogen 2.899 N/A ASN 50.A N ASP 105.A OD2 no hydrogen 2.727 N/A ILE 51.A N GLY 76.A O no hydrogen 2.868 N/A ALA 52.A N GLY 106.A O no hydrogen 3.184 N/A ILE 53.A N THR 78.A O no hydrogen 3.082 N/A LEU 54.A N GLU 108.A O no hydrogen 2.998 N/A PHE 55.A N ILE 80.A O no hydrogen 2.794 N/A GLN 56.A N ARG 110.A O no hydrogen 2.945 N/A ARG 63.A N SER 59.A O no hydrogen 2.967 N/A ARG 63.A NE GLU 67.A OE1 no hydrogen 2.819 N/A ARG 63.A NH2 GLU 67.A OE1 no hydrogen 3.363 N/A ARG 63.A NH2 GLU 67.A OE2 no hydrogen 3.510 N/A CYS 64.A N THR 60.A O no hydrogen 2.924 N/A CYS 64.A SG THR 60.A O no hydrogen 3.408 N/A ALA 65.A N ARG 61.A O no hydrogen 2.995 N/A PHE 66.A N THR 62.A O no hydrogen 3.138 N/A GLU 67.A N ARG 63.A O no hydrogen 2.889 N/A VAL 68.A N CYS 64.A O no hydrogen 3.033 N/A ALA 69.A N ALA 65.A O no hydrogen 2.989 N/A ALA 70.A N PHE 66.A O no hydrogen 2.865 N/A SER 71.A N GLU 67.A O no hydrogen 3.195 N/A ASP 72.A N VAL 68.A O no hydrogen 2.997 N/A LEU 73.A N ALA 69.A O no hydrogen 3.248 N/A GLY 74.A N SER 71.A O no hydrogen 3.022 N/A ALA 75.A N ALA 70.A O no hydrogen 2.991 N/A GLY 76.A N LYS 49.A O no hydrogen 3.068 N/A THR 78.A N ILE 51.A O no hydrogen 2.945 N/A THR 78.A OG1 TYR 104.A OH no hydrogen 3.267 N/A ILE 80.A N ILE 53.A O no hydrogen 2.918 N/A SER 85.A N PRO 82.A O no hydrogen 3.223 N/A SER 85.A OG PHE 55.A O no hydrogen 3.354 N/A SER 85.A OG ILE 80.A O no hydrogen 2.797 N/A SER 85.A OG GLY 81.A O no hydrogen 2.873 N/A GLY 88.A N GLU 91.A O no hydrogen 3.014 N/A LYS 89.A NZ MET 87.A O no hydrogen 3.144 N/A THR 96.A N SER 92.A O no hydrogen 3.027 N/A THR 96.A OG1 GLU 91.A OE1 no hydrogen 2.864 N/A THR 96.A OG1 SER 92.A O no hydrogen 3.410 N/A ALA 97.A N ILE 93.A O no hydrogen 2.898 N/A LYS 98.A N GLU 94.A O no hydrogen 3.269 N/A LYS 98.A NZ GLU 94.A OE2 no hydrogen 3.071 N/A VAL 99.A N THR 96.A O no hydrogen 3.087 N/A LEU 100.A N THR 96.A O no hydrogen 3.143 N/A GLY 101.A N ALA 97.A O no hydrogen 3.181 N/A ARG 102.A N VAL 99.A O no hydrogen 2.868 N/A PHE 103.A N VAL 99.A O no hydrogen 3.306 N/A PHE 103.A N LEU 100.A O no hydrogen 3.347 N/A TYR 104.A N LEU 100.A O no hydrogen 2.940 N/A ASP 105.A N ASN 50.A O no hydrogen 2.878 N/A ILE 107.A N PRO 127.A O no hydrogen 2.948 N/A GLU 108.A N ALA 52.A O no hydrogen 2.909 N/A PHE 109.A N TRP 129.A O no hydrogen 2.895 N/A ARG 110.A N LEU 54.A O no hydrogen 3.016 N/A GLY 111.A N LEU 132.A O no hydrogen 3.066 N/A GLN 114.A NE2 ASP 11.A O no hydrogen 2.987 N/A ASP 116.A N ALA 113.A O no hydrogen 3.100 N/A ASP 118.A N GLN 114.A O no hydrogen 3.071 N/A ALA 119.A N SER 115.A O no hydrogen 3.048 N/A LEU 120.A N ASP 116.A O no hydrogen 3.079 N/A VAL 121.A N VAL 117.A O no hydrogen 2.878 N/A LYS 122.A N ASP 118.A O no hydrogen 2.917 N/A TYR 123.A N ALA 119.A O no hydrogen 2.889 N/A SER 124.A N LEU 120.A O no hydrogen 2.974 N/A SER 124.A OG LEU 120.A O no hydrogen 2.770 N/A VAL 126.A N SER 124.A OG no hydrogen 3.250 N/A VAL 128.A N SER 9.A OG no hydrogen 2.972 N/A TRP 129.A N ILE 107.A O no hydrogen 2.716 N/A ASN 130.A N LEU 10.A O no hydrogen 2.867 N/A ASN 130.A ND2 ASP 11.A O no hydrogen 2.957 N/A ASN 130.A ND2 GLN 114.A OE1 no hydrogen 3.476 N/A ASN 130.A ND2 GLU 136.A O no hydrogen 3.637 N/A GLY 131.A N PHE 109.A O no hydrogen 2.635 N/A LEU 132.A N ASN 130.A OD1 no hydrogen 3.034 N/A THR 133.A N GLU 136.A O no hydrogen 2.988 N/A THR 133.A OG1 GLN 114.A OE1 no hydrogen 2.655 N/A THR 133.A OG1 GLU 136.A O no hydrogen 3.371 N/A ASP 134.A N PHE 112.A O no hydrogen 3.037 N/A ASP 135.A N THR 133.A OG1 no hydrogen 3.117 N/A GLU 136.A N THR 133.A OG1 no hydrogen 3.038 N/A HIS 137.A N SER 173.A OG no hydrogen 3.161 N/A GLN 140.A NE2 ASP 144.A OD1 no hydrogen 3.493 N/A ILE 141.A N HIS 137.A O no hydrogen 3.176 N/A ILE 142.A N PRO 138.A O no hydrogen 3.291 N/A ALA 143.A N THR 139.A O no hydrogen 3.224 N/A ASP 144.A N GLN 140.A O no hydrogen 2.931 N/A PHE 145.A N ILE 141.A O no hydrogen 3.102 N/A MET 146.A N ILE 142.A O no hydrogen 3.096 N/A THR 147.A N ALA 143.A O no hydrogen 3.138 N/A THR 147.A OG1 ALA 143.A O no hydrogen 2.629 N/A MET 148.A N ASP 144.A O no hydrogen 3.195 N/A LYS 149.A N PHE 145.A O no hydrogen 2.939 N/A LYS 149.A NZ ASP 26.A OD1 no hydrogen 2.690 N/A GLU 150.A N MET 146.A O no hydrogen 2.786 N/A LYS 151.A N MET 148.A O no hydrogen 2.839 N/A PHE 152.A N MET 148.A O no hydrogen 2.843 N/A GLY 153.A N LYS 149.A O no hydrogen 2.920 N/A LYS 156.A N ASN 154.A OD1 no hydrogen 3.244 N/A LYS 156.A NZ ASN 212.A O no hydrogen 3.278 N/A ASN 157.A N GLY 182.A O no hydrogen 2.804 N/A LYS 158.A N LEU 155.A O no hydrogen 2.977 N/A LYS 159.A N ASP 230.A OD2 no hydrogen 2.907 N/A LYS 159.A NZ ALA 225.A O no hydrogen 2.747 N/A LYS 159.A NZ GLN 227.A O no hydrogen 2.894 N/A ILE 160.A N HIS 184.A O no hydrogen 2.919 N/A VAL 161.A N VAL 231.A O no hydrogen 2.788 N/A PHE 162.A N VAL 186.A O no hydrogen 2.917 N/A ILE 163.A N TYR 233.A O no hydrogen 2.867 N/A GLY 164.A N CYS 188.A O no hydrogen 2.710 N/A TYR 166.A OH PRO 190.A O no hydrogen 3.369 N/A LYS 167.A NZ ASP 165.A OD1 no hydrogen 2.688 N/A ASN 168.A N ASP 165.A O no hydrogen 3.089 N/A ASN 168.A ND2 ASP 235.A OD2 no hydrogen 2.881 N/A ASN 169.A ND2 THR 133.A O no hydrogen 2.872 N/A ASN 169.A ND2 ASP 134.A O no hydrogen 3.574 N/A GLY 171.A N ASN 168.A OD1 no hydrogen 2.800 N/A VAL 172.A N ASN 168.A O no hydrogen 2.934 N/A SER 173.A N ASN 169.A O no hydrogen 2.743 N/A SER 173.A OG ASN 169.A O no hydrogen 2.800 N/A THR 174.A N VAL 170.A O no hydrogen 2.830 N/A THR 174.A OG1 VAL 170.A O no hydrogen 2.673 N/A MET 175.A N GLY 171.A O no hydrogen 3.000 N/A ILE 176.A N VAL 172.A O no hydrogen 3.138 N/A GLY 177.A N SER 173.A O no hydrogen 3.156 N/A ALA 178.A N THR 174.A O no hydrogen 3.050 N/A ALA 178.A N MET 175.A O no hydrogen 3.093 N/A ALA 179.A N MET 175.A O no hydrogen 3.053 N/A ALA 179.A N ILE 176.A O no hydrogen 3.017 N/A PHE 180.A N ILE 176.A O no hydrogen 3.109 N/A ASN 181.A N GLY 177.A O no hydrogen 3.222 N/A ASN 181.A ND2 GLY 177.A O no hydrogen 2.899 N/A GLY 182.A N ALA 179.A O no hydrogen 3.106 N/A MET 183.A N ALA 178.A O no hydrogen 2.917 N/A HIS 184.A N LYS 158.A O no hydrogen 2.800 N/A HIS 184.A ND1 SER 215.A OG no hydrogen 2.641 N/A VAL 185.A N SER 215.A O no hydrogen 2.750 N/A VAL 186.A N ILE 160.A O no hydrogen 2.870 N/A MET 187.A N ARG 217.A O no hydrogen 2.977 N/A CYS 188.A N PHE 162.A O no hydrogen 2.865 N/A GLY 189.A N SER 219.A O no hydrogen 3.034 N/A ASN 192.A N ASN 192.A OD1 no hydrogen 2.550 N/A TYR 193.A N PRO 190.A O no hydrogen 3.268 N/A LYS 194.A NZ ASP 191.A OD1 no hydrogen 3.070 N/A ASN 195.A N ASN 192.A O no hydrogen 3.236 N/A GLU 196.A N TYR 193.A O no hydrogen 2.797 N/A ILE 197.A N LYS 194.A O no hydrogen 3.370 N/A VAL 201.A N ASP 198.A OD1 no hydrogen 2.747 N/A LEU 202.A N ASP 198.A O no hydrogen 3.462 N/A ALA 203.A N LYS 199.A O no hydrogen 2.951 N/A LYS 204.A N ASN 200.A O no hydrogen 2.820 N/A CYS 205.A N VAL 201.A O no hydrogen 2.795 N/A CYS 205.A SG VAL 201.A O no hydrogen 3.399 N/A ILE 206.A N LEU 202.A O no hydrogen 2.788 N/A GLU 207.A N ALA 203.A O no hydrogen 2.957 N/A LEU 208.A N LYS 204.A O no hydrogen 3.005 N/A PHE 209.A N CYS 205.A O no hydrogen 2.977 N/A LYS 210.A N ILE 206.A O no hydrogen 2.958 N/A ARG 211.A N GLU 207.A O no hydrogen 3.272 N/A ASN 212.A N LEU 208.A O no hydrogen 2.757 N/A ASN 212.A ND2 THR 18.A OG1 no hydrogen 2.935 N/A ASN 212.A ND2 ALA 179.A O no hydrogen 3.136 N/A GLY 213.A N PHE 209.A O no hydrogen 2.827 N/A GLY 214.A N ASN 157.A OD1 no hydrogen 3.456 N/A SER 215.A N MET 183.A O no hydrogen 3.073 N/A SER 215.A OG HIS 184.A ND1 no hydrogen 2.641 N/A ARG 217.A N VAL 185.A O no hydrogen 2.999 N/A SER 219.A N MET 187.A O no hydrogen 2.945 N/A SER 219.A OG ASP 221.A O no hydrogen 3.347 N/A ASP 221.A N SER 219.A OG no hydrogen 3.196 N/A LYS 222.A NZ GLN 258.A O no hydrogen 3.045 N/A LYS 222.A NZ ASP 260.A OD1 no hydrogen 3.386 N/A LYS 222.A NZ ASP 260.A OD2 no hydrogen 2.716 N/A LEU 224.A N ASP 221.A OD1 no hydrogen 2.875 N/A ALA 225.A N ASP 221.A O no hydrogen 2.999 N/A ALA 226.A N LYS 222.A O no hydrogen 3.040 N/A GLN 227.A N LEU 224.A O no hydrogen 3.133 N/A ALA 229.A N ALA 226.A O no hydrogen 3.103 N/A ASP 230.A N LYS 159.A O no hydrogen 2.718 N/A VAL 231.A N LYS 159.A O no hydrogen 3.026 N/A ILE 232.A N ILE 272.A O no hydrogen 2.926 N/A TYR 233.A N VAL 161.A O no hydrogen 2.768 N/A TYR 233.A OH ASP 144.A OD2 no hydrogen 2.641 N/A THR 234.A N LEU 274.A O no hydrogen 3.096 N/A THR 234.A OG1 ILE 163.A O no hydrogen 2.818 N/A ASP 235.A N THR 234.A OG1 no hydrogen 2.697 N/A SER 239.A N GLU 242.A OE1 no hydrogen 3.253 N/A GLU 242.A N SER 239.A O no hydrogen 3.071 N/A ASP 248.A N PHE 244.A O no hydrogen 2.782 N/A LYS 249.A NZ GLU 253.A OE2 no hydrogen 3.157 N/A ARG 250.A N LEU 246.A O no hydrogen 3.055 N/A ILE 251.A N PHE 247.A O no hydrogen 2.972 N/A GLY 252.A N ASP 248.A O no hydrogen 3.036 N/A GLU 253.A N LYS 249.A O no hydrogen 2.960 N/A LEU 254.A N ARG 250.A O no hydrogen 2.877 N/A PHE 257.A N LEU 254.A O no hydrogen 2.872 N/A GLN 258.A NE2 MET 307.A O no hydrogen 2.685 N/A VAL 259.A N GLU 308.A O no hydrogen 2.668 N/A MET 263.A N ASP 260.A OD1 no hydrogen 3.049 N/A ILE 264.A N ASP 260.A O no hydrogen 3.101 N/A LYS 265.A N MET 261.A O no hydrogen 2.796 N/A ALA 266.A N ASN 262.A O no hydrogen 3.040 N/A ALA 266.A N MET 263.A O no hydrogen 3.130 N/A ALA 267.A N ILE 264.A O no hydrogen 3.238 N/A LYS 268.A N ALA 229.A O no hydrogen 3.318 N/A VAL 271.A N LYS 268.A O no hydrogen 3.014 N/A ILE 272.A N ASP 230.A O no hydrogen 3.018 N/A PHE 273.A N HIS 318.A O no hydrogen 2.762 N/A LEU 274.A N ILE 232.A O no hydrogen 2.788 N/A HIS 275.A N GLN 324.A OE1 no hydrogen 3.057 N/A HIS 275.A NE2 GLU 308.A OE2 no hydrogen 3.138 N/A CYS 276.A SG ASP 235.A OD1 no hydrogen 3.848 N/A CYS 276.A SG LEU 277.A O no hydrogen 3.924 N/A LEU 277.A N HIS 275.A ND1 no hydrogen 2.633 N/A PHE 280.A N GLU 308.A OE2 no hydrogen 2.930 N/A HIS 281.A ND1 ASP 311.A OD1 no hydrogen 2.705 N/A HIS 284.A N ASP 282.A OD1 no hydrogen 2.761 N/A HIS 284.A ND1 ASP 283.A OD1 no hydrogen 3.263 N/A THR 285.A OG1 SER 288.A OG no hydrogen 2.588 N/A SER 288.A N THR 285.A OG1 no hydrogen 2.984 N/A SER 288.A OG ASP 282.A O no hydrogen 2.773 N/A SER 288.A OG THR 285.A O no hydrogen 3.564 N/A SER 288.A OG THR 285.A OG1 no hydrogen 2.588 N/A LYS 289.A N THR 285.A O no hydrogen 3.158 N/A LYS 289.A N SER 286.A O no hydrogen 3.164 N/A GLU 290.A N SER 286.A O no hydrogen 3.153 N/A VAL 291.A N PHE 287.A O no hydrogen 3.254 N/A ALA 292.A N SER 288.A O no hydrogen 3.146 N/A THR 293.A N LYS 289.A O no hydrogen 2.944 N/A THR 293.A OG1 LYS 289.A O no hydrogen 2.927 N/A THR 294.A N GLU 290.A O no hydrogen 3.132 N/A THR 294.A OG1 GLU 290.A O no hydrogen 3.251 N/A LEU 295.A N VAL 291.A O no hydrogen 2.829 N/A GLY 296.A N ALA 292.A O no hydrogen 2.935 N/A LYS 298.A NZ ASP 248.A OD2 no hydrogen 3.090 N/A TYR 299.A N LEU 295.A O no hydrogen 2.956 N/A TYR 299.A OH ASP 248.A O no hydrogen 3.207 N/A TYR 299.A OH ASP 248.A OD1 no hydrogen 2.667 N/A VAL 302.A N TYR 299.A O no hydrogen 3.143 N/A ALA 303.A N PRO 300.A O no hydrogen 3.067 N/A GLY 305.A N VAL 302.A O no hydrogen 3.127 N/A MET 307.A N PHE 280.A O no hydrogen 3.093 N/A GLU 308.A N GLU 308.A OE1 no hydrogen 2.629 N/A THR 310.A N VAL 259.A O no hydrogen 3.268 N/A PHE 314.A N THR 310.A O no hydrogen 3.066 N/A GLN 315.A N ASP 311.A O no hydrogen 2.878 N/A GLN 315.A NE2 ASP 311.A OD1 no hydrogen 3.482 N/A SER 316.A N VAL 313.A O no hydrogen 2.878 N/A SER 316.A OG VAL 313.A O no hydrogen 3.185 N/A HIS 318.A N SER 316.A OG no hydrogen 2.755 N/A HIS 318.A ND1 VAL 271.A O no hydrogen 2.811 N/A ASN 319.A N SER 316.A O no hydrogen 3.150 N/A ASN 319.A ND2 PHE 314.A O no hydrogen 2.942 N/A LYS 320.A N PHE 273.A O no hydrogen 3.176 N/A LYS 320.A NZ LEU 317.A O no hydrogen 2.950 N/A ALA 321.A N ASN 319.A OD1 no hydrogen 2.959 N/A GLN 324.A N LYS 320.A O no hydrogen 3.066 N/A GLN 324.A NE2 ASP 144.A OD1 no hydrogen 2.696 N/A ALA 325.A N ALA 321.A O no hydrogen 3.158 N/A GLU 326.A N PHE 322.A O no hydrogen 3.175 N/A ASN 327.A N ASP 323.A O no hydrogen 2.914 N/A ASN 327.A ND2 THR 147.A OG1 no hydrogen 2.997 N/A ASN 327.A ND2 GLU 150.A OE1 no hydrogen 2.819 N/A ARG 328.A N ALA 325.A O no hydrogen 2.860 N/A ARG 328.A NH1 THR 62.A OG1 no hydrogen 3.213 N/A ARG 328.A NH2 THR 62.A OG1 no hydrogen 2.855 N/A ARG 328.A NH2 THR 139.A OG1 no hydrogen 2.854 N/A MET 329.A N GLU 326.A O no hydrogen 3.120 N/A HIS 330.A NE2 GLU 326.A OE2 no hydrogen 2.764 N/A SER 331.A N ASN 327.A O no hydrogen 3.038 N/A SER 331.A OG ASN 327.A O no hydrogen 2.735 N/A SER 331.A OG ARG 328.A O no hydrogen 2.950 N/A ILE 332.A N ARG 328.A O no hydrogen 3.048 N/A LYS 333.A N MET 329.A O no hydrogen 3.038 N/A LYS 333.A NZ ASP 72.A OD2 no hydrogen 3.077 N/A ALA 334.A N HIS 330.A O no hydrogen 3.180 N/A ILE 335.A N SER 331.A O no hydrogen 3.037 N/A ILE 336.A N ILE 332.A O no hydrogen 2.943 N/A LEU 337.A N LYS 333.A O no hydrogen 3.036 N/A SER 338.A N ALA 334.A O no hydrogen 3.101 N/A SER 338.A OG ALA 334.A O no hydrogen 3.126 N/A THR 339.A N ILE 335.A O no hydrogen 3.302 N/A THR 339.A OG1 ARG 8.A O no hydrogen 2.994 N/A ILE 340.A N ILE 336.A O no hydrogen 2.861 N/A GLY 341.A N LEU 337.A O no hydrogen 2.687 N/A