Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4ar2_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 2.A OG1 PRO 1.A O no hydrogen 2.843 N/A SER 7.A OG ARG 5.A O no hydrogen 3.003 N/A THR 19.A OG1 PRO 449.A O no hydrogen 2.887 N/A THR 20.A OG1 LYS 21.A O no hydrogen 3.245 N/A LEU 22.A N VAL 447.A O no hydrogen 2.968 N/A LEU 24.A N GLY 445.A O no hydrogen 3.155 N/A LYS 28.A NZ ASP 31.A OD2 no hydrogen 3.452 N/A LYS 28.A NZ THR 47.A O no hydrogen 3.061 N/A LYS 28.A NZ THR 47.A OG1 no hydrogen 3.125 N/A ASP 31.A N LYS 28.A O no hydrogen 3.101 N/A SER 34.A N ALA 30.A O no hydrogen 3.161 N/A LEU 35.A N ASP 31.A O no hydrogen 2.789 N/A ASN 36.A N ILE 32.A O no hydrogen 2.731 N/A SER 42.A N ASP 40.A OD1 no hydrogen 2.705 N/A SER 42.A OG VAL 429.A O no hydrogen 2.627 N/A ASN 43.A N ASP 40.A OD1 no hydrogen 3.180 N/A PHE 44.A N VAL 427.A O no hydrogen 3.211 N/A THR 46.A N GLN 425.A O no hydrogen 2.824 N/A THR 46.A OG1 VAL 25.A O no hydrogen 2.453 N/A THR 47.A OG1 VAL 49.A O no hydrogen 3.025 N/A VAL 48.A N GLY 423.A O no hydrogen 2.512 N/A GLN 50.A NE2 VAL 48.A O no hydrogen 2.784 N/A ASN 51.A ND2 ASN 52.A OD1 no hydrogen 3.334 N/A THR 55.A N GLU 58.A OE2 no hydrogen 2.861 N/A THR 55.A OG1 THR 57.A OG1 no hydrogen 3.044 N/A THR 57.A OG1 THR 55.A OG1 no hydrogen 3.044 N/A ALA 59.A N THR 55.A O no hydrogen 2.985 N/A SER 60.A N PRO 56.A O no hydrogen 2.734 N/A SER 60.A OG THR 57.A O no hydrogen 2.980 N/A THR 61.A N GLU 58.A O no hydrogen 3.137 N/A THR 63.A OG1 ILE 64.A O no hydrogen 2.769 N/A ILE 64.A N ILE 421.A O no hydrogen 2.944 N/A PHE 66.A N SER 419.A O no hydrogen 3.104 N/A SER 70.A OG GLU 68.A O no hydrogen 3.170 N/A GLY 73.A N ARG 450.A O no hydrogen 3.249 N/A GLY 74.A N LEU 415.A O no hydrogen 2.607 N/A GLN 75.A N ALA 448.A O no hydrogen 2.745 N/A GLN 75.A NE2 ASP 411.A OD2 no hydrogen 3.293 N/A LEU 76.A N GLY 413.A O no hydrogen 3.112 N/A LYS 77.A N ILE 446.A O no hydrogen 3.045 N/A THR 78.A N THR 410.A O no hydrogen 2.695 N/A ILE 79.A N LEU 444.A O no hydrogen 2.852 N/A MET 80.A N ALA 408.A O no hydrogen 3.178 N/A HIS 81.A N LYS 442.A O no hydrogen 3.003 N/A ASN 83.A N TYR 439.A O no hydrogen 2.847 N/A ASN 86.A ND2 VAL 316.A O no hydrogen 2.744 N/A VAL 87.A N GLY 135.A O no hydrogen 2.635 N/A ASN 88.A N PRO 85.A O no hydrogen 2.996 N/A GLU 89.A N GLU 134.A OE2 no hydrogen 2.615 N/A TYR 90.A N ASN 88.A OD1 no hydrogen 2.433 N/A PHE 92.A N GLU 89.A O no hydrogen 2.757 N/A SER 93.A N ASN 88.A O no hydrogen 3.070 N/A SER 93.A OG ASN 86.A O no hydrogen 2.842 N/A SER 93.A OG ASN 88.A O no hydrogen 2.512 N/A LYS 97.A N ASP 211.A O no hydrogen 2.992 N/A ALA 98.A N PHE 128.A O no hydrogen 3.218 N/A ARG 99.A N GLY 209.A O no hydrogen 2.995 N/A ARG 99.A NE GLY 207.A O no hydrogen 2.863 N/A ARG 99.A NH2 GLY 207.A O no hydrogen 3.164 N/A VAL 102.A N LYS 124.A O no hydrogen 2.750 N/A LYS 105.A N ILE 122.A O no hydrogen 3.277 N/A GLU 108.A N ALA 106.A O no hydrogen 2.905 N/A THR 111.A OG1 THR 115.A OG1 no hydrogen 3.238 N/A THR 115.A OG1 THR 111.A OG1 no hydrogen 3.238 N/A HIS 118.A N ASP 114.A O no hydrogen 2.285 N/A GLU 120.A N ASP 117.A O no hydrogen 3.200 N/A ASP 121.A N HIS 118.A O no hydrogen 3.148 N/A LYS 124.A N SER 103.A O no hydrogen 3.102 N/A LYS 124.A NZ LEU 123.A O no hydrogen 3.211 N/A PHE 128.A N ALA 98.A O no hydrogen 3.050 N/A PHE 130.A N PHE 96.A O no hydrogen 3.259 N/A LEU 132.A N ASN 94.A O no hydrogen 3.062 N/A ASN 136.A ND2 SER 403.A O no hydrogen 3.200 N/A PHE 137.A N ASN 86.A OD1 no hydrogen 2.711 N/A ALA 139.A N THR 401.A O no hydrogen 3.157 N/A MET 141.A N SER 138.A OG no hydrogen 3.259 N/A THR 142.A N SER 138.A O no hydrogen 3.371 N/A THR 142.A OG1 SER 138.A O no hydrogen 2.869 N/A THR 142.A OG1 ALA 139.A O no hydrogen 3.009 N/A LEU 145.A N MET 141.A O no hydrogen 2.921 N/A MET 146.A N THR 142.A O no hydrogen 3.145 N/A MET 146.A N ILE 143.A O no hydrogen 2.640 N/A ASN 147.A N ILE 143.A O no hydrogen 2.597 N/A ALA 149.A N LEU 145.A O no hydrogen 2.892 N/A ASP 152.A N ASN 148.A O no hydrogen 2.484 N/A ASN 153.A ND2 ILE 150.A O no hydrogen 3.624 N/A TYR 154.A N ILE 150.A O no hydrogen 3.353 N/A TYR 154.A OH VAL 163.A O no hydrogen 3.159 N/A LEU 155.A N ILE 151.A O no hydrogen 2.852 N/A ILE 157.A N ASN 153.A O no hydrogen 3.047 N/A ILE 157.A N TYR 154.A O no hydrogen 2.653 N/A GLY 158.A N TYR 154.A O no hydrogen 2.403 N/A ARG 159.A NE LEU 155.A O no hydrogen 2.747 N/A ARG 159.A NH2 LEU 155.A O no hydrogen 3.548 N/A ASN 161.A N GLY 158.A O no hydrogen 2.964 N/A VAL 163.A N GLY 158.A O no hydrogen 2.974 N/A LEU 164.A N ASP 167.A OD2 no hydrogen 2.869 N/A SER 166.A OG ASP 167.A OD1 no hydrogen 3.264 N/A SER 166.A OG SER 277.A O no hydrogen 3.416 N/A LYS 171.A N VAL 203.A O no hydrogen 2.792 N/A LYS 171.A NZ ILE 390.A O no hydrogen 2.747 N/A LYS 171.A NZ ILE 392.A O no hydrogen 3.412 N/A ASP 173.A N ASP 201.A O no hydrogen 2.478 N/A ARG 175.A NH1 GLN 389.A O no hydrogen 3.050 N/A ARG 175.A NH2 GLN 389.A O no hydrogen 3.278 N/A ARG 175.A NH2 ILE 390.A O no hydrogen 3.468 N/A ASN 176.A ND2 PHE 177.A O no hydrogen 3.291 N/A LEU 179.A N ASN 176.A O no hydrogen 2.682 N/A TRP 181.A N ARG 178.A O no hydrogen 3.016 N/A THR 185.A N ASP 182.A OD1 no hydrogen 3.027 N/A LYS 186.A NZ PRO 183.A O no hydrogen 3.569 N/A MET 189.A N GLY 180.A O no hydrogen 3.241 N/A GLY 191.A N ILE 188.A O no hydrogen 2.885 N/A TYR 193.A N GLN 389.A OE1 no hydrogen 3.315 N/A TYR 195.A OH ARG 393.A O no hydrogen 2.764 N/A PHE 198.A N THR 174.A OG1 no hydrogen 2.746 N/A HIS 199.A N THR 174.A OG1 no hydrogen 3.223 N/A HIS 199.A NE2 GLY 222.A O no hydrogen 3.113 N/A HIS 199.A NE2 THR 312.A O no hydrogen 3.117 N/A VAL 203.A N LYS 171.A O no hydrogen 2.832 N/A LEU 204.A N ARG 290.A O no hydrogen 2.495 N/A LEU 205.A N GLY 169.A O no hydrogen 3.019 N/A CYS 208.A SG GLY 169.A O no hydrogen 3.471 N/A CYS 208.A SG LEU 205.A O no hydrogen 3.138 N/A CYS 208.A SG PRO 206.A O no hydrogen 3.559 N/A GLY 209.A N ARG 99.A O no hydrogen 3.263 N/A VAL 210.A N ILE 235.A O no hydrogen 2.804 N/A ASP 211.A N LYS 97.A O no hydrogen 3.166 N/A THR 213.A OG1 ASP 211.A OD1 no hydrogen 2.906 N/A THR 213.A OG1 GLU 231.A OE1 no hydrogen 2.585 N/A THR 213.A OG1 PHE 233.A O no hydrogen 3.512 N/A SER 215.A N PHE 212.A O no hydrogen 2.289 N/A SER 215.A OG PHE 92.A O no hydrogen 3.400 N/A SER 215.A OG LYS 95.A O no hydrogen 3.218 N/A ARG 216.A N PHE 92.A O no hydrogen 2.901 N/A ARG 216.A NH1 CYS 318.A O no hydrogen 2.193 N/A LEU 217.A N SER 215.A OG no hydrogen 3.134 N/A SER 218.A OG ILE 223.A O no hydrogen 2.779 N/A ASN 219.A N ARG 216.A O no hydrogen 2.510 N/A LEU 220.A N LEU 217.A O no hydrogen 2.684 N/A LEU 221.A N LEU 217.A O no hydrogen 2.792 N/A ILE 223.A N SER 218.A O no hydrogen 3.419 N/A ARG 224.A N LEU 310.A O no hydrogen 3.157 N/A ARG 226.A NE THR 309.A O no hydrogen 2.775 N/A ILE 235.A N VAL 210.A O no hydrogen 2.684 N/A MET 236.A N ASP 239.A OD2 no hydrogen 3.130 N/A ASP 239.A N MET 236.A O no hydrogen 2.747 N/A GLY 243.A N GLU 241.A O no hydrogen 2.259 N/A ILE 245.A N TYR 289.A O no hydrogen 2.494 N/A ASP 250.A N GLN 267.A O no hydrogen 3.243 N/A THR 252.A OG1 ASP 250.A OD1 no hydrogen 3.054 N/A ALA 253.A N ASP 250.A OD1 no hydrogen 3.414 N/A GLU 255.A N VAL 251.A O no hydrogen 2.901 N/A GLU 256.A N THR 252.A O no hydrogen 3.020 N/A SER 257.A OG ALA 253.A O no hydrogen 2.596 N/A LYS 262.A N GLU 263.A OE2 no hydrogen 3.463 N/A ASP 272.A N ARG 276.A O no hydrogen 2.964 N/A SER 273.A OG ASP 272.A OD2 no hydrogen 3.190 N/A LYS 274.A N ASP 272.A OD2 no hydrogen 3.061 N/A SER 275.A N ASP 272.A O no hydrogen 2.598 N/A SER 275.A OG LYS 274.A O no hydrogen 2.681 N/A ARG 276.A NH1 GLU 387.A OE1 no hydrogen 3.174 N/A ARG 276.A NH2 GLU 165.A OE2 no hydrogen 2.725 N/A TYR 278.A N GLU 270.A O no hydrogen 3.084 N/A ASN 279.A N SER 277.A OG no hydrogen 3.076 N/A LYS 284.A N GLU 282.A O no hydrogen 2.229 N/A ASN 286.A ND2 ASP 283.A OD1 no hydrogen 3.391 N/A THR 287.A N PRO 246.A O no hydrogen 2.855 N/A THR 287.A OG1 TYR 278.A O no hydrogen 2.855 N/A ALA 288.A N ASN 279.A O no hydrogen 3.514 N/A TYR 289.A N THR 287.A O no hydrogen 2.620 N/A TYR 289.A OH SER 166.A O no hydrogen 2.487 N/A ARG 290.A N LEU 204.A O no hydrogen 2.828 N/A ARG 290.A NH1 TYR 237.A O no hydrogen 2.844 N/A SER 291.A N GLY 243.A O no hydrogen 2.816 N/A SER 291.A OG ASP 201.A OD1 no hydrogen 2.738 N/A TRP 292.A N ILE 202.A O no hydrogen 3.174 N/A TYR 293.A N ASP 201.A OD2 no hydrogen 2.889 N/A SER 295.A N SER 291.A O no hydrogen 3.392 N/A SER 295.A OG SER 291.A O no hydrogen 3.150 N/A SER 295.A OG TRP 292.A O no hydrogen 2.366 N/A TYR 296.A N TRP 292.A O no hydrogen 3.046 N/A ASN 297.A N TYR 293.A O no hydrogen 2.707 N/A TYR 298.A N LEU 294.A O no hydrogen 2.536 N/A GLY 299.A N LEU 294.A O no hydrogen 3.027 N/A GLY 299.A N SER 295.A O no hydrogen 3.290 N/A ASN 300.A N SER 295.A O no hydrogen 3.117 N/A ASN 300.A ND2 GLU 241.A O no hydrogen 2.437 N/A ARG 306.A NH1 ASN 297.A O no hydrogen 3.559 N/A THR 309.A N ILE 305.A O no hydrogen 2.855 N/A LEU 310.A N ARG 224.A O no hydrogen 2.777 N/A LEU 311.A N TYR 296.A OH no hydrogen 3.183 N/A THR 312.A N GLY 222.A O no hydrogen 2.797 N/A THR 312.A OG1 THR 313.A O no hydrogen 3.161 N/A CYS 318.A SG ASN 86.A O no hydrogen 3.933 N/A CYS 318.A SG VAL 316.A O no hydrogen 3.492 N/A CYS 318.A SG THR 317.A O no hydrogen 3.025 N/A CYS 318.A SG CYS 318.A O no hydrogen 2.750 N/A GLN 322.A N GLN 322.A OE1 no hydrogen 2.629 N/A GLN 322.A NE2 TYR 324.A OH no hydrogen 3.393 N/A VAL 323.A N GLU 352.A O no hydrogen 3.095 N/A TYR 324.A N THR 430.A O no hydrogen 2.617 N/A TRP 325.A N GLY 350.A O no hydrogen 2.509 N/A SER 326.A N THR 428.A O no hydrogen 2.741 N/A SER 326.A OG THR 428.A O no hydrogen 3.296 N/A GLN 332.A N PRO 416.A O no hydrogen 2.745 N/A THR 336.A OG1 VAL 335.A O no hydrogen 2.440 N/A PHE 337.A N VAL 335.A O no hydrogen 2.782 N/A SER 339.A OG ASP 333.A OD2 no hydrogen 3.492 N/A GLN 342.A N THR 340.A OG1 no hydrogen 2.904 N/A ASN 345.A N GLN 342.A O no hydrogen 2.608 N/A VAL 349.A N TRP 325.A O no hydrogen 2.701 N/A GLY 350.A N TRP 325.A O no hydrogen 2.998 N/A GLU 352.A N VAL 323.A O no hydrogen 3.354 N/A MET 354.A N GLU 321.A O no hydrogen 2.695 N/A PHE 357.A N GLU 404.A O no hydrogen 3.213 N/A LYS 359.A N VAL 402.A O no hydrogen 3.109 N/A PHE 361.A N THR 400.A O no hydrogen 3.014 N/A ALA 366.A N ASN 363.A O no hydrogen 3.162 N/A TYR 368.A N GLN 365.A O no hydrogen 2.691 N/A SER 369.A N ALA 366.A O no hydrogen 2.860 N/A SER 369.A OG ASN 363.A OD1 no hydrogen 3.003 N/A GLN 370.A N VAL 367.A O no hydrogen 3.165 N/A GLN 371.A N VAL 367.A O no hydrogen 3.190 N/A ARG 373.A N GLN 370.A O no hydrogen 3.248 N/A THR 376.A OG1 LEU 372.A O no hydrogen 2.500 N/A SER 377.A OG ARG 373.A O no hydrogen 2.854 N/A SER 377.A OG THR 379.A O no hydrogen 2.557 N/A ASN 388.A N GLU 387.A OE1 no hydrogen 2.887 N/A VAL 402.A N LYS 359.A O no hydrogen 2.806 N/A GLU 404.A N PHE 357.A O no hydrogen 3.146 N/A VAL 406.A N PRO 355.A O no hydrogen 3.033 N/A ALA 408.A N MET 80.A O no hydrogen 2.759 N/A THR 410.A N THR 78.A O no hydrogen 2.849 N/A THR 410.A OG1 THR 78.A O no hydrogen 3.486 N/A THR 410.A OG1 GLU 352.A OE2 no hydrogen 2.624 N/A HIS 412.A N LEU 76.A O no hydrogen 3.035 N/A LEU 415.A N GLY 74.A O no hydrogen 2.770 N/A LEU 417.A N TRP 72.A O no hydrogen 3.169 N/A ARG 418.A N MET 330.A O no hydrogen 2.914 N/A ARG 418.A NE MET 331.A O no hydrogen 3.169 N/A ARG 418.A NH2 ASP 333.A OD1 no hydrogen 3.414 N/A ILE 421.A N ILE 64.A O no hydrogen 3.179 N/A GLY 423.A N GLN 62.A O no hydrogen 3.104 N/A GLN 425.A N THR 46.A O no hydrogen 2.944 N/A VAL 429.A N SER 42.A O no hydrogen 2.565 N/A THR 430.A N TYR 324.A O no hydrogen 2.663 N/A ASP 431.A N ARG 435.A O no hydrogen 2.824 N/A ARG 433.A N ASP 431.A OD1 no hydrogen 3.184 N/A ARG 435.A NE ASP 431.A OD1 no hydrogen 2.972 N/A CYS 437.A N SER 42.A OG no hydrogen 2.983 N/A TYR 441.A N HIS 81.A O no hydrogen 3.045 N/A LYS 442.A NZ ASP 26.A OD1 no hydrogen 2.587 N/A LEU 444.A N ILE 79.A O no hydrogen 2.756 N/A ILE 446.A N LYS 77.A O no hydrogen 3.153 N/A VAL 447.A N LEU 22.A O no hydrogen 3.168 N/A ALA 448.A N GLN 75.A O no hydrogen 3.078 N/A ARG 450.A N GLY 73.A O no hydrogen 2.759 N/A SER 453.A OG ARG 71.A O no hydrogen 3.368 N/A SER 453.A OG LEU 452.A O no hydrogen 2.618 N/A SER 454.A OG SER 453.A O no hydrogen 2.486 N/A