Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4asx_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 1.A N ASN 38.A O no hydrogen 3.562 N/A LEU 10.A N LEU 17.A O no hydrogen 2.760 N/A PHE 12.A N MET 15.A O no hydrogen 2.788 N/A MET 15.A N PHE 12.A O no hydrogen 2.891 N/A LEU 17.A N LEU 10.A O no hydrogen 2.795 N/A GLN 18.A N GLN 35.A O no hydrogen 2.962 N/A GLN 18.A NE2 THR 7.A OG1 no hydrogen 3.333 N/A GLN 18.A NE2 GLU 8.A O no hydrogen 2.698 N/A LEU 20.A N LYS 33.A O no hydrogen 2.764 N/A LYS 23.A N VAL 31.A O no hydrogen 2.782 N/A LYS 23.A NZ GLU 96.A O no hydrogen 2.804 N/A ALA 24.A N VAL 31.A O no hydrogen 3.295 N/A ARG 25.A NE GLY 26.A O no hydrogen 3.536 N/A GLY 26.A N GLY 29.A O no hydrogen 2.717 N/A ARG 27.A NE ASP 147.A OD2 no hydrogen 3.063 N/A ARG 27.A NH2 ASP 147.A OD1 no hydrogen 3.479 N/A ARG 27.A NH2 ASP 147.A OD2 no hydrogen 2.818 N/A CYS 30.A N ILE 45.A O no hydrogen 2.916 N/A VAL 31.A N ALA 24.A O no hydrogen 2.869 N/A TRP 32.A N VAL 43.A O no hydrogen 2.868 N/A LYS 33.A N GLU 21.A O no hydrogen 2.915 N/A LYS 33.A NZ GLU 96.A OE1 no hydrogen 3.008 N/A ALA 34.A N VAL 41.A O no hydrogen 2.754 N/A GLN 35.A N GLN 18.A O no hydrogen 2.764 N/A GLN 35.A NE2 LEU 37.A O no hydrogen 3.408 N/A LEU 36.A N GLU 39.A O no hydrogen 2.774 N/A LEU 37.A N PRO 16.A O no hydrogen 3.005 N/A GLU 39.A N LEU 36.A O no hydrogen 3.002 N/A VAL 41.A N ALA 34.A O no hydrogen 2.869 N/A ALA 42.A N THR 92.A O no hydrogen 2.953 N/A VAL 43.A N TRP 32.A O no hydrogen 2.859 N/A LYS 44.A N.A LEU 90.A O no hydrogen 2.777 N/A LYS 44.A N.B LEU 90.A O no hydrogen 2.760 N/A LYS 44.A NZ.A GLU 57.A OE1 no hydrogen 2.681 N/A LYS 44.A NZ.A ASP 165.A OD2 no hydrogen 3.375 N/A LYS 44.A NZ.B GLU 57.A OE1 no hydrogen 2.715 N/A LYS 44.A NZ.B GLU 57.A OE2 no hydrogen 2.721 N/A ILE 45.A N CYS 30.A O no hydrogen 2.805 N/A PHE 46.A N LEU 88.A O no hydrogen 3.077 N/A GLN 49.A N GLN 49.A OE1 no hydrogen 2.786 N/A ASP 50.A N PRO 47.A O no hydrogen 2.806 N/A LYS 51.A N ILE 48.A O no hydrogen 3.035 N/A SER 53.A N ASP 50.A O no hydrogen 3.010 N/A TRP 54.A N ASP 50.A O no hydrogen 3.250 N/A TRP 54.A NE1 TRP 89.A O no hydrogen 2.989 N/A GLN 55.A N LYS 51.A O no hydrogen 2.932 N/A GLN 55.A NE2 GLU 59.A OE2 no hydrogen 2.935 N/A ASN 56.A N GLN 52.A O no hydrogen 2.866 N/A ASN 56.A ND2 PHE 166.A O no hydrogen 2.922 N/A ASN 56.A ND2 ALA 169.A O no hydrogen 2.881 N/A GLU 57.A N SER 53.A O no hydrogen 2.858 N/A TYR 58.A N TRP 54.A O no hydrogen 3.042 N/A GLU 59.A N GLN 55.A O no hydrogen 2.839 N/A VAL 60.A N ASN 56.A O no hydrogen 2.857 N/A TYR 61.A N GLU 57.A O no hydrogen 2.882 N/A TYR 61.A OH LEU 72.A O no hydrogen 2.973 N/A SER 62.A N GLU 59.A O no hydrogen 3.042 N/A SER 62.A OG TYR 58.A O no hydrogen 2.695 N/A LEU 63.A N VAL 60.A O no hydrogen 3.100 N/A GLY 65.A N ASP 137.A OD2 no hydrogen 3.252 N/A LYS 67.A N.A GLY 65.A O no hydrogen 2.924 N/A LYS 67.A N.B GLY 65.A O no hydrogen 2.934 N/A LYS 67.A NZ.B GLN 73.A OE1 no hydrogen 3.040 N/A ASN 70.A N HIS 68.A ND1 no hydrogen 2.944 N/A ASN 70.A ND2 ALA 161.A O no hydrogen 2.993 N/A ILE 71.A N HIS 68.A O no hydrogen 3.105 N/A LEU 72.A N ILE 163.A O no hydrogen 2.980 N/A ILE 75.A N ILE 91.A O no hydrogen 2.800 N/A GLY 76.A N ILE 91.A O no hydrogen 3.117 N/A GLU 78.A N TRP 89.A O no hydrogen 3.011 N/A ARG 80.A N ASP 87.A O no hydrogen 2.841 N/A ARG 80.A NH1 TYR 11.A O no hydrogen 3.016 N/A ARG 80.A NH1 GLU 78.A OE1 no hydrogen 2.877 N/A ARG 80.A NH2 TYR 11.A O no hydrogen 3.028 N/A THR 82.A N ASP 85.A O no hydrogen 3.177 N/A VAL 84.A N THR 82.A OG1 no hydrogen 3.151 N/A ASP 85.A N THR 82.A OG1 no hydrogen 3.051 N/A ASP 87.A N ARG 80.A O no hydrogen 2.795 N/A TRP 89.A N GLU 78.A O no hydrogen 2.989 N/A LEU 90.A N LYS 44.A O.A no hydrogen 2.861 N/A LEU 90.A N LYS 44.A O.B no hydrogen 2.854 N/A ILE 91.A N GLY 76.A O no hydrogen 2.768 N/A THR 92.A N ALA 42.A O no hydrogen 2.927 N/A THR 92.A OG1 ALA 93.A O no hydrogen 2.845 N/A ALA 93.A N GLN 73.A O no hydrogen 2.933 N/A LYS 97.A NZ ASN 157.A O no hydrogen 3.232 N/A GLY 98.A N HIS 95.A O no hydrogen 2.878 N/A LEU 100.A N VAL 153.A O no hydrogen 2.709 N/A SER 101.A N SER 150.A O no hydrogen 3.251 N/A ASP 102.A N SER 99.A OG no hydrogen 3.039 N/A PHE 103.A N SER 99.A O no hydrogen 3.003 N/A LEU 104.A N LEU 100.A O no hydrogen 2.836 N/A LYS 105.A N SER 101.A O no hydrogen 3.062 N/A ALA 106.A N PHE 103.A O no hydrogen 3.077 N/A ASN 107.A ND2 PHE 103.A O no hydrogen 2.893 N/A VAL 109.A N ARG 224.A O no hydrogen 3.050 N/A SER 110.A N GLU 113.A OE1 no hydrogen 2.941 N/A GLU 113.A N SER 110.A OG no hydrogen 3.188 N/A LEU 114.A N SER 110.A O no hydrogen 2.849 N/A CYS 115.A N TRP 111.A O no hydrogen 3.018 N/A CYS 115.A SG TRP 111.A O no hydrogen 3.366 N/A HIS 116.A N ASN 112.A O no hydrogen 3.066 N/A HIS 116.A NE2 THR 160.A OG1 no hydrogen 2.886 N/A ILE 117.A N GLU 113.A O no hydrogen 3.024 N/A ALA 118.A N LEU 114.A O no hydrogen 2.853 N/A GLU 119.A N CYS 115.A O no hydrogen 2.845 N/A THR 120.A N HIS 116.A O no hydrogen 3.066 N/A THR 120.A OG1 HIS 116.A O no hydrogen 2.693 N/A THR 120.A OG1 ILE 117.A O no hydrogen 3.208 N/A MET 121.A N ILE 117.A O no hydrogen 2.941 N/A ALA 122.A N ALA 118.A O no hydrogen 3.015 N/A ARG 123.A N GLU 119.A O no hydrogen 2.893 N/A ARG 123.A NE GLU 119.A OE2 no hydrogen 2.918 N/A ARG 123.A NH1 GLU 301.A OE2 no hydrogen 3.330 N/A ARG 123.A NH2 GLU 301.A OE1 no hydrogen 3.440 N/A ARG 123.A NH2 THR 304.A OG1 no hydrogen 3.012 N/A GLY 124.A N THR 120.A O no hydrogen 3.008 N/A LEU 125.A N MET 121.A O no hydrogen 2.953 N/A ALA 126.A N ALA 122.A O no hydrogen 2.825 N/A TYR 127.A N ARG 123.A O no hydrogen 3.046 N/A TYR 127.A OH GLY 65.A O no hydrogen 2.519 N/A LEU 128.A N GLY 124.A O no hydrogen 2.993 N/A HIS 129.A N LEU 125.A O no hydrogen 2.871 N/A HIS 129.A NE2 ASP 210.A OD2 no hydrogen 2.878 N/A GLU 130.A N.A TYR 127.A O no hydrogen 2.975 N/A GLU 130.A N.B TYR 127.A O no hydrogen 2.954 N/A ILE 132.A N LYS 140.A O no hydrogen 2.747 N/A LEU 135.A N GLY 138.A O no hydrogen 3.011 N/A GLY 138.A N LEU 135.A O no hydrogen 2.918 N/A HIS 139.A NE2 ASP 131.A OD1 no hydrogen 2.710 N/A LYS 140.A N ILE 132.A O no hydrogen 2.878 N/A LYS 140.A NZ TYR 127.A O no hydrogen 3.026 N/A LYS 140.A NZ LEU 128.A O no hydrogen 2.796 N/A LYS 140.A NZ GLU 130.A O.A no hydrogen 2.702 N/A LYS 140.A NZ GLU 130.A O.B no hydrogen 2.698 N/A LYS 140.A NZ PRO 141.A O no hydrogen 2.793 N/A ILE 143.A N LEU 128.A O no hydrogen 2.944 N/A SER 144.A N LEU 170.A O no hydrogen 2.914 N/A SER 144.A OG LEU 170.A O no hydrogen 2.929 N/A HIS 145.A N ASP 210.A OD2 no hydrogen 2.808 N/A HIS 145.A NE2 ALA 164.A O no hydrogen 2.909 N/A ARG 146.A N ASP 210.A OD1 no hydrogen 2.997 N/A ASP 147.A N HIS 145.A ND1 no hydrogen 3.093 N/A LYS 149.A NZ THR 186.A OG1 no hydrogen 2.658 N/A SER 150.A OG TYR 189.A OH no hydrogen 3.411 N/A SER 150.A OG GLU 220.A OE1 no hydrogen 2.569 N/A SER 150.A OG GLU 220.A OE2 no hydrogen 3.330 N/A LYS 151.A NZ ASP 102.A OD1 no hydrogen 3.478 N/A ASN 152.A N LYS 149.A O no hydrogen 3.012 N/A ASN 152.A ND2 ASP 147.A O no hydrogen 2.819 N/A VAL 153.A N SER 150.A O no hydrogen 3.452 N/A LEU 154.A N CYS 162.A O no hydrogen 2.846 N/A LEU 155.A N GLY 98.A O no hydrogen 2.929 N/A LYS 156.A N THR 160.A O no hydrogen 2.784 N/A LYS 156.A NZ GLU 69.A O no hydrogen 2.786 N/A LEU 159.A N LYS 156.A O no hydrogen 2.848 N/A THR 160.A N ASN 158.A OD1 no hydrogen 3.246 N/A THR 160.A OG1 HIS 116.A NE2 no hydrogen 2.886 N/A THR 160.A OG1 ASN 158.A OD1 no hydrogen 2.816 N/A ALA 161.A N THR 120.A OG1 no hydrogen 2.977 N/A CYS 162.A N LEU 154.A O no hydrogen 2.872 N/A CYS 162.A SG HIS 95.A NE2 no hydrogen 3.914 N/A CYS 162.A SG LEU 154.A O no hydrogen 3.902 N/A ILE 163.A N ASN 70.A O no hydrogen 2.980 N/A ALA 164.A N ASN 152.A O no hydrogen 2.883 N/A PHE 166.A N GLU 57.A OE2 no hydrogen 2.910 N/A GLY 167.A N ASP 165.A OD1 no hydrogen 3.057 N/A ALA 169.A N PHE 166.A O no hydrogen 3.272 N/A LEU 170.A N SER 144.A O no hydrogen 2.956 N/A PHE 172.A N ALA 142.A O no hydrogen 2.865 N/A SER 177.A OG ASN 200.A OD1 no hydrogen 2.724 N/A ALA 178.A N PHE 201.A O no hydrogen 2.882 N/A GLY 179.A N SER 177.A OG no hydrogen 3.334 N/A THR 180.A N ILE 199.A O no hydrogen 2.561 N/A HIS 181.A ND1 GLY 197.A O no hydrogen 2.518 N/A GLN 183.A NE2 VAL 194.A O no hydrogen 3.025 N/A THR 186.A OG1 ASP 147.A OD1 no hydrogen 2.684 N/A THR 186.A OG1 ASP 147.A OD2 no hydrogen 3.439 N/A ARG 187.A NH1 PRO 247.A O no hydrogen 2.950 N/A ARG 188.A NH1 PRO 238.A O no hydrogen 2.822 N/A ARG 188.A NH1 GLY 244.A O no hydrogen 3.202 N/A ARG 188.A NH2 GLY 244.A O no hydrogen 3.232 N/A TYR 189.A N THR 186.A O no hydrogen 3.156 N/A TYR 189.A OH GLU 220.A OE2 no hydrogen 2.558 N/A MET 190.A N ARG 187.A O no hydrogen 2.969 N/A GLU 193.A N GLU 193.A OE1 no hydrogen 2.744 N/A LEU 195.A N ALA 191.A O no hydrogen 3.078 N/A GLU 196.A N PRO 192.A O no hydrogen 3.014 N/A GLY 197.A N GLU 193.A O no hydrogen 3.209 N/A GLY 197.A N VAL 194.A O no hydrogen 2.943 N/A ALA 198.A N GLU 193.A O no hydrogen 3.273 N/A ILE 199.A N THR 180.A O no hydrogen 2.670 N/A PHE 201.A N GLY 179.A O no hydrogen 2.983 N/A GLN 202.A NE2 GLY 175.A O no hydrogen 2.894 N/A ARG 203.A NE ASP 204.A OD1 no hydrogen 3.507 N/A ALA 205.A N GLN 202.A OE1 no hydrogen 3.231 N/A PHE 206.A N GLN 202.A O no hydrogen 3.218 N/A LEU 207.A N ARG 203.A O no hydrogen 2.945 N/A ARG 208.A N ASP 204.A O no hydrogen 2.962 N/A ILE 209.A N ALA 205.A O no hydrogen 3.257 N/A ASP 210.A N PHE 206.A O no hydrogen 3.286 N/A MET 211.A N LEU 207.A O no hydrogen 3.025 N/A TYR 212.A N ARG 208.A O no hydrogen 3.200 N/A ALA 213.A N ILE 209.A O no hydrogen 3.342 N/A MET 214.A N ASP 210.A O no hydrogen 2.813 N/A GLY 215.A N MET 211.A O no hydrogen 2.957 N/A LEU 216.A N TYR 212.A O no hydrogen 3.224 N/A VAL 217.A N ALA 213.A O no hydrogen 3.058 N/A LEU 218.A N MET 214.A O no hydrogen 2.993 N/A TRP 219.A N GLY 215.A O no hydrogen 3.033 N/A TRP 219.A NE1 VAL 264.A O no hydrogen 2.994 N/A GLU 220.A N LEU 216.A O no hydrogen 2.997 N/A LEU 221.A N VAL 217.A O no hydrogen 3.054 N/A ALA 222.A N LEU 218.A O no hydrogen 2.959 N/A SER 223.A N TRP 219.A O no hydrogen 2.815 N/A SER 223.A OG GLU 220.A O no hydrogen 2.588 N/A ARG 224.A N LEU 221.A O no hydrogen 3.098 N/A ARG 224.A NE LEU 104.A O no hydrogen 2.760 N/A ARG 224.A NH1 ASP 233.A O no hydrogen 2.875 N/A ARG 224.A NH2 LEU 104.A O no hydrogen 2.979 N/A ARG 224.A NH2 ASN 107.A O no hydrogen 3.032 N/A CYS 225.A N ALA 222.A O no hydrogen 3.140 N/A CYS 225.A SG VAL 109.A O no hydrogen 3.652 N/A THR 226.A N VAL 109.A O no hydrogen 2.870 N/A THR 226.A OG1 VAL 109.A O no hydrogen 3.406 N/A ASP 229.A N THR 226.A O no hydrogen 2.871 N/A GLU 234.A N ASP 233.A OD1 no hydrogen 2.792 N/A TYR 235.A OH GLU 220.A OE1 no hydrogen 2.395 N/A LEU 237.A N GLU 240.A OE1 no hydrogen 2.718 N/A GLU 240.A N LEU 237.A O no hydrogen 2.961 N/A GLU 242.A N GLU 242.A OE1 no hydrogen 2.723 N/A ILE 243.A N PHE 239.A O no hydrogen 2.848 N/A GLY 244.A N GLU 240.A O no hydrogen 2.744 N/A SER 248.A N ASP 251.A OD2 no hydrogen 2.903 N/A ASP 251.A N SER 248.A OG no hydrogen 2.931 N/A MET 252.A N SER 248.A O no hydrogen 3.177 N/A GLN 253.A N LEU 249.A O no hydrogen 2.850 N/A GLN 253.A NE2 LEU 195.A O no hydrogen 2.795 N/A GLU 254.A N.A GLU 250.A O no hydrogen 2.982 N/A GLU 254.A N.B GLU 250.A O no hydrogen 2.975 N/A VAL 255.A N ASP 251.A O no hydrogen 3.051 N/A VAL 256.A N MET 252.A O no hydrogen 2.850 N/A VAL 257.A N GLN 253.A O no hydrogen 2.951 N/A HIS 258.A N GLN 253.A O no hydrogen 3.076 N/A HIS 258.A ND1 GLU 254.A OE2.A no hydrogen 3.163 N/A LYS 259.A N GLU 254.A O.A no hydrogen 2.977 N/A LYS 259.A N GLU 254.A O.B no hydrogen 2.961 N/A LYS 259.A NZ GLU 254.A OE2.B no hydrogen 2.734 N/A LYS 261.A N VAL 255.A O no hydrogen 2.910 N/A ARG 262.A NE TRP 286.A O no hydrogen 2.902 N/A ARG 262.A NH1 VAL 256.A O no hydrogen 3.347 N/A ARG 262.A NH1 LYS 261.A O no hydrogen 2.919 N/A ARG 262.A NH2 TRP 286.A O no hydrogen 2.884 N/A TYR 268.A OH PRO 231.A O no hydrogen 2.750 N/A TRP 269.A N ARG 266.A O no hydrogen 3.183 N/A GLN 270.A N ASP 267.A O no hydrogen 2.939 N/A GLN 270.A NE2 ARG 266.A O no hydrogen 3.516 N/A LYS 271.A N TYR 268.A O no hydrogen 3.239 N/A HIS 272.A N TRP 269.A O no hydrogen 3.498 N/A GLY 274.A N HIS 272.A ND1 no hydrogen 3.143 N/A MET 275.A N HIS 272.A ND1 no hydrogen 3.073 N/A ALA 276.A N HIS 272.A O no hydrogen 2.906 N/A MET 277.A N ALA 273.A O no hydrogen 3.268 N/A LEU 278.A N GLY 274.A O no hydrogen 2.902 N/A CYS 279.A N MET 275.A O no hydrogen 2.774 N/A CYS 279.A SG MET 275.A O no hydrogen 3.364 N/A GLU 280.A N ALA 276.A O no hydrogen 3.010 N/A THR 281.A N MET 277.A O no hydrogen 3.079 N/A THR 281.A OG1 MET 277.A O no hydrogen 3.093 N/A ILE 282.A N LEU 278.A O no hydrogen 2.878 N/A GLU 283.A N CYS 279.A O no hydrogen 3.023 N/A GLU 284.A N GLU 280.A O no hydrogen 3.164 N/A CYS 285.A N THR 281.A O no hydrogen 3.002 N/A CYS 285.A SG THR 281.A O no hydrogen 3.410 N/A TRP 286.A N ILE 282.A O no hydrogen 2.941 N/A ASP 289.A N ASP 287.A OD1 no hydrogen 2.743 N/A GLU 291.A N ASP 289.A OD1 no hydrogen 3.110 N/A ALA 292.A N ASP 289.A O no hydrogen 2.863 N/A ARG 293.A N ALA 290.A O no hydrogen 2.951 N/A ARG 293.A NE ASP 287.A O no hydrogen 2.894 N/A ARG 293.A NH1 GLU 193.A OE2 no hydrogen 2.800 N/A ARG 293.A NH1 ARG 208.A O no hydrogen 2.966 N/A ARG 293.A NH2 GLU 193.A OE1 no hydrogen 2.999 N/A ARG 293.A NH2 ASP 287.A O no hydrogen 2.938 N/A CYS 298.A N.A SER 295.A OG no hydrogen 3.071 N/A CYS 298.A N.B SER 295.A OG no hydrogen 3.068 N/A CYS 298.A SG.B SER 295.A OG no hydrogen 3.152 N/A VAL 299.A N SER 295.A O no hydrogen 3.092 N/A GLY 300.A N ALA 296.A O no hydrogen 3.066 N/A GLU 301.A N GLY 297.A O no hydrogen 3.213 N/A GLU 301.A N CYS 298.A O.A no hydrogen 2.861 N/A ARG 302.A N CYS 298.A O.A no hydrogen 2.961 N/A ARG 302.A N CYS 298.A O.B no hydrogen 3.148 N/A ARG 302.A NH1 GLU 284.A OE2 no hydrogen 2.973 N/A ARG 302.A NH2 GLU 284.A OE2 no hydrogen 2.929 N/A ILE 303.A N VAL 299.A O no hydrogen 2.958 N/A THR 304.A N GLY 300.A O no hydrogen 3.141 N/A THR 304.A OG1 GLY 300.A O no hydrogen 3.254 N/A GLN 305.A N GLU 301.A O no hydrogen 2.806 N/A MET 306.A N ARG 302.A O no hydrogen 2.800 N/A GLN 307.A N ILE 303.A O no hydrogen 2.835 N/A GLN 307.A NE2 ASN 112.A OD1 no hydrogen 2.736 N/A ARG 308.A N THR 304.A O no hydrogen 3.049 N/A ARG 308.A N GLN 305.A O no hydrogen 3.122 N/A LEU 309.A N MET 306.A O no hydrogen 3.202 N/A