Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4bde_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 8.A N PRO 5.A O no hydrogen 3.135 N/A ARG 9.A N PRO 5.A O no hydrogen 3.081 N/A ASP 10.A N LYS 6.A O no hydrogen 2.922 N/A GLU 11.A N LEU 8.A O no hydrogen 3.061 N/A TYR 12.A N LEU 8.A O no hydrogen 2.840 N/A ILE 13.A N PHE 24.A O no hydrogen 2.929 N/A SER 15.A N LEU 22.A O no hydrogen 2.627 N/A LEU 18.A N VAL 20.A O no hydrogen 2.689 N/A LYS 21.A N ILE 34.A O no hydrogen 2.831 N/A LEU 22.A N LYS 16.A O no hydrogen 2.701 N/A ALA 23.A N VAL 32.A O no hydrogen 3.007 N/A PHE 24.A N ILE 13.A O no hydrogen 2.893 N/A GLU 25.A N LYS 30.A O no hydrogen 2.959 N/A ARG 26.A N GLU 11.A O no hydrogen 2.877 N/A ARG 26.A NE ARG 9.A O no hydrogen 2.830 N/A ARG 26.A NH2 ARG 9.A O no hydrogen 2.736 N/A ARG 26.A NH2 TYR 12.A O no hydrogen 3.413 N/A CYS 29.A N GLU 25.A O no hydrogen 2.740 N/A CYS 29.A SG ARG 26.A O no hydrogen 3.935 N/A LYS 30.A N THR 28.A OG1 no hydrogen 3.269 N/A VAL 32.A N ALA 23.A O no hydrogen 2.800 N/A ALA 33.A N LEU 74.A O no hydrogen 2.958 N/A ILE 34.A N LYS 21.A O no hydrogen 2.705 N/A LYS 35.A N ILE 72.A O no hydrogen 2.755 N/A ILE 36.A N GLU 19.A O no hydrogen 2.700 N/A ILE 37.A N TYR 70.A O no hydrogen 2.972 N/A LYS 39.A NZ ASP 66.A OD1 no hydrogen 2.674 N/A LYS 39.A NZ ALA 67.A O no hydrogen 2.770 N/A GLU 44.A N ALA 40.A O no hydrogen 3.037 N/A THR 45.A N LEU 41.A O no hydrogen 3.142 N/A GLU 46.A N ASN 42.A O no hydrogen 2.983 N/A ILE 47.A N VAL 43.A O no hydrogen 2.834 N/A GLU 48.A N GLU 44.A O no hydrogen 3.035 N/A ILE 49.A N THR 45.A O no hydrogen 2.784 N/A LEU 50.A N GLU 46.A O no hydrogen 2.801 N/A LYS 51.A N ILE 47.A O no hydrogen 2.890 N/A LYS 52.A N GLU 48.A O no hydrogen 3.275 N/A LEU 53.A N ILE 49.A O no hydrogen 3.129 N/A ASN 54.A N TYR 110.A OH no hydrogen 2.904 N/A CYS 57.A N HIS 55.A ND1 no hydrogen 2.947 N/A CYS 57.A SG GLN 103.A OE1 no hydrogen 3.918 N/A ILE 58.A N HIS 55.A O no hydrogen 3.247 N/A ILE 59.A N ILE 139.A O no hydrogen 3.155 N/A LYS 60.A N GLU 75.A OE1 no hydrogen 2.837 N/A LYS 60.A NZ ASN 54.A OD1 no hydrogen 2.796 N/A LYS 62.A N VAL 73.A O no hydrogen 2.723 N/A ASN 63.A N VAL 73.A O no hydrogen 3.373 N/A ASN 63.A ND2 TYR 12.A OH no hydrogen 3.076 N/A PHE 64.A N ASN 63.A OD1 no hydrogen 2.805 N/A PHE 65.A N TYR 71.A O no hydrogen 2.746 N/A ALA 67.A N ASP 69.A O no hydrogen 3.217 N/A TYR 70.A N ILE 37.A O no hydrogen 2.820 N/A TYR 71.A N PHE 65.A O no hydrogen 2.795 N/A ILE 72.A N LYS 35.A O no hydrogen 2.782 N/A VAL 73.A N ASN 63.A O no hydrogen 2.879 N/A LEU 74.A N ALA 33.A O no hydrogen 2.740 N/A GLY 79.A N LEU 128.A O no hydrogen 2.869 N/A GLY 80.A N MET 77.A O no hydrogen 3.254 N/A LEU 82.A N VAL 126.A O no hydrogen 2.773 N/A PHE 83.A N PRO 123.A O no hydrogen 2.988 N/A LYS 85.A N LEU 82.A O no hydrogen 2.821 N/A VAL 86.A N PHE 83.A O no hydrogen 3.007 N/A VAL 87.A N PHE 83.A O no hydrogen 2.944 N/A LYS 90.A NZ ASP 84.A O no hydrogen 3.240 N/A LYS 90.A NZ VAL 87.A O no hydrogen 3.521 N/A ARG 91.A NE LEU 192.A O no hydrogen 3.442 N/A ARG 91.A NH1 VAL 222.A O no hydrogen 3.306 N/A ARG 91.A NH2 LEU 192.A O no hydrogen 2.926 N/A ARG 91.A NH2 VAL 222.A O no hydrogen 2.964 N/A LEU 92.A N CYS 191.A O no hydrogen 3.425 N/A LYS 93.A NZ GLU 133.A OE1 no hydrogen 3.323 N/A LYS 93.A NZ GLU 133.A OE2 no hydrogen 3.169 N/A THR 96.A N LYS 93.A O no hydrogen 2.913 N/A THR 96.A OG1 GLU 133.A OE1 no hydrogen 3.075 N/A CYS 97.A N LYS 93.A O no hydrogen 3.098 N/A CYS 97.A SG LEU 92.A O no hydrogen 3.697 N/A CYS 97.A SG LYS 93.A O no hydrogen 3.590 N/A LYS 98.A N GLU 94.A O no hydrogen 2.951 N/A LYS 98.A NZ TRP 256.A O no hydrogen 2.838 N/A LYS 98.A NZ ASP 259.A OD2 no hydrogen 2.825 N/A LEU 99.A N ALA 95.A O no hydrogen 3.092 N/A TYR 100.A N THR 96.A O no hydrogen 2.985 N/A TYR 100.A OH GLU 133.A O no hydrogen 2.640 N/A PHE 101.A N CYS 97.A O no hydrogen 2.796 N/A TYR 102.A N LYS 98.A O no hydrogen 2.980 N/A GLN 103.A NE2 LEU 99.A O no hydrogen 2.867 N/A GLN 103.A NE2 CYS 135.A O no hydrogen 3.439 N/A MET 104.A N TYR 100.A O no hydrogen 3.098 N/A LEU 105.A N PHE 101.A O no hydrogen 2.801 N/A LEU 106.A N TYR 102.A O no hydrogen 2.940 N/A ALA 107.A N GLN 103.A O no hydrogen 2.888 N/A VAL 108.A N MET 104.A O no hydrogen 2.855 N/A GLN 109.A N LEU 105.A O no hydrogen 2.823 N/A TYR 110.A N LEU 106.A O no hydrogen 3.094 N/A LEU 111.A N ALA 107.A O no hydrogen 3.052 N/A HIS 112.A N VAL 108.A O no hydrogen 2.984 N/A HIS 112.A NE2 ASP 180.A OD2 no hydrogen 2.967 N/A GLU 113.A N GLN 109.A O no hydrogen 2.828 N/A ASN 114.A N TYR 110.A O no hydrogen 3.061 N/A ASN 114.A N LEU 111.A O no hydrogen 3.041 N/A ASN 114.A ND2 TYR 110.A O no hydrogen 2.758 N/A GLY 115.A N HIS 112.A O no hydrogen 3.116 N/A ILE 116.A N LEU 111.A O no hydrogen 2.904 N/A ILE 117.A N LYS 146.A O no hydrogen 2.979 N/A HIS 118.A N ASP 180.A OD2 no hydrogen 2.890 N/A HIS 118.A NE2 THR 140.A O no hydrogen 2.665 N/A ARG 119.A N ASP 180.A OD1 no hydrogen 2.946 N/A ASP 120.A N HIS 118.A ND1 no hydrogen 3.087 N/A LYS 122.A NZ ASP 120.A OD2 no hydrogen 3.323 N/A ASN 125.A N LYS 122.A O no hydrogen 2.975 N/A ASN 125.A ND2 ASP 120.A O no hydrogen 2.613 N/A ASN 125.A ND2 ASP 141.A OD2 no hydrogen 3.403 N/A VAL 126.A N PRO 123.A O no hydrogen 3.476 N/A LEU 127.A N LYS 138.A O no hydrogen 2.837 N/A LEU 128.A N GLY 80.A O no hydrogen 2.793 N/A SER 129.A N LEU 136.A O no hydrogen 2.806 N/A SER 129.A OG LEU 136.A O no hydrogen 3.066 N/A CYS 135.A SG TYR 100.A OH no hydrogen 3.772 N/A CYS 135.A SG SER 130.A O no hydrogen 3.901 N/A CYS 135.A SG GLU 132.A O no hydrogen 3.608 N/A CYS 135.A SG LEU 136.A O no hydrogen 3.855 N/A LEU 136.A N SER 129.A OG no hydrogen 2.934 N/A ILE 137.A N GLN 103.A OE1 no hydrogen 2.780 N/A LYS 138.A N LEU 127.A O no hydrogen 2.787 N/A LYS 138.A NZ PRO 56.A O no hydrogen 2.909 N/A LYS 138.A NZ GLU 273.A OE2 no hydrogen 3.375 N/A ILE 139.A N CYS 57.A O no hydrogen 2.907 N/A THR 140.A N ASN 125.A O no hydrogen 2.794 N/A SER 145.A N PHE 142.A O no hydrogen 3.225 N/A SER 145.A OG PHE 142.A O no hydrogen 2.502 N/A LYS 146.A N ILE 117.A O no hydrogen 2.890 N/A LEU 148.A N GLY 115.A O no hydrogen 2.803 N/A MET 152.A N THR 149.A OG1 no hydrogen 3.403 N/A ARG 153.A N THR 149.A O no hydrogen 3.516 N/A THR 154.A N SER 150.A O no hydrogen 3.015 N/A THR 154.A OG1 SER 150.A O no hydrogen 2.699 N/A LEU 155.A N LEU 151.A O no hydrogen 2.869 N/A CYS 156.A N MET 152.A O no hydrogen 3.241 N/A CYS 156.A N ARG 153.A O no hydrogen 3.289 N/A CYS 156.A SG MET 152.A O no hydrogen 3.494 N/A THR 158.A OG1 THR 160.A OG1 no hydrogen 3.397 N/A THR 160.A OG1 THR 158.A OG1 no hydrogen 3.397 N/A LEU 162.A N PRO 159.A O no hydrogen 2.831 N/A GLU 165.A N GLU 165.A OE1 no hydrogen 2.755 N/A VAL 166.A N ALA 163.A O no hydrogen 3.197 N/A VAL 168.A N PRO 164.A O no hydrogen 2.981 N/A SER 169.A N GLU 165.A O no hydrogen 3.025 N/A SER 169.A OG VAL 166.A O no hydrogen 2.584 N/A VAL 170.A N LEU 167.A O no hydrogen 3.303 N/A GLY 171.A N VAL 168.A O no hydrogen 3.348 N/A ALA 173.A N SER 169.A O no hydrogen 3.114 N/A ALA 178.A N TYR 175.A O no hydrogen 3.130 N/A VAL 179.A N ASN 176.A O no hydrogen 3.122 N/A ASP 180.A N ARG 177.A O no hydrogen 3.089 N/A TRP 182.A N ALA 178.A O no hydrogen 3.115 N/A SER 183.A N VAL 179.A O no hydrogen 3.146 N/A SER 183.A OG VAL 179.A O no hydrogen 3.160 N/A LEU 184.A N ASP 180.A O no hydrogen 2.933 N/A GLY 185.A N CYS 181.A O no hydrogen 3.059 N/A VAL 186.A N TRP 182.A O no hydrogen 2.967 N/A ILE 187.A N SER 183.A O no hydrogen 2.780 N/A LEU 188.A N LEU 184.A O no hydrogen 2.864 N/A PHE 189.A N GLY 185.A O no hydrogen 3.053 N/A ILE 190.A N VAL 186.A O no hydrogen 3.089 N/A CYS 191.A N ILE 187.A O no hydrogen 2.936 N/A CYS 191.A SG ILE 187.A O no hydrogen 3.441 N/A LEU 192.A N LEU 188.A O no hydrogen 2.996 N/A SER 193.A N PHE 189.A O no hydrogen 3.020 N/A SER 193.A OG PHE 189.A O no hydrogen 2.735 N/A SER 193.A OG TYR 195.A O no hydrogen 3.159 N/A GLY 194.A N ILE 190.A O no hydrogen 2.695 N/A TYR 195.A N SER 193.A OG no hydrogen 3.425 N/A TYR 195.A OH ASN 217.A O no hydrogen 2.650 N/A SER 199.A N GLN 210.A OE1 no hydrogen 3.213 N/A LEU 207.A N GLU 200.A OE2 no hydrogen 3.466 N/A ASP 209.A N SER 206.A OG no hydrogen 3.337 N/A GLN 210.A N SER 206.A O no hydrogen 2.970 N/A GLN 210.A NE2 SER 199.A O no hydrogen 2.770 N/A GLN 210.A NE2 VAL 205.A O no hydrogen 3.073 N/A ILE 211.A N LEU 207.A O no hydrogen 3.067 N/A THR 212.A N LYS 208.A O no hydrogen 2.943 N/A THR 212.A OG1 LYS 208.A O no hydrogen 3.349 N/A THR 212.A OG1 ASP 209.A O no hydrogen 3.488 N/A SER 213.A N ASP 209.A O no hydrogen 2.980 N/A SER 213.A OG ASP 209.A O no hydrogen 2.933 N/A SER 213.A OG GLN 210.A O no hydrogen 3.308 N/A GLY 214.A N ILE 211.A O no hydrogen 3.063 N/A LYS 215.A N GLN 210.A O no hydrogen 3.130 N/A LYS 215.A N SER 213.A OG no hydrogen 3.347 N/A ASN 217.A N PRO 197.A O no hydrogen 2.764 N/A ILE 219.A N TYR 195.A OH no hydrogen 2.852 N/A GLU 221.A N GLU 221.A OE1 no hydrogen 2.934 N/A VAL 222.A N ILE 219.A O no hydrogen 3.227 N/A TRP 223.A N ILE 219.A O no hydrogen 3.136 N/A TRP 223.A NE1 TYR 195.A OH no hydrogen 2.959 N/A ALA 224.A N PRO 220.A O no hydrogen 2.850 N/A VAL 226.A N TRP 223.A O no hydrogen 2.955 N/A SER 227.A N GLU 94.A OE1 no hydrogen 2.786 N/A SER 227.A OG GLU 94.A OE2 no hydrogen 2.877 N/A ALA 230.A N SER 227.A OG no hydrogen 3.181 N/A LEU 231.A N SER 227.A O no hydrogen 3.454 N/A ASP 232.A N GLU 228.A O no hydrogen 2.977 N/A LEU 233.A N LYS 229.A O no hydrogen 3.128 N/A VAL 234.A N ALA 230.A O no hydrogen 3.268 N/A LYS 235.A N LEU 231.A O no hydrogen 2.986 N/A LYS 236.A N ASP 232.A O no hydrogen 3.226 N/A LYS 236.A NZ ASP 232.A OD2 no hydrogen 2.846 N/A LEU 237.A N LEU 233.A O no hydrogen 3.090 N/A LEU 237.A N VAL 234.A O no hydrogen 3.026 N/A LEU 238.A N VAL 234.A O no hydrogen 2.798 N/A LYS 243.A N ASP 241.A OD1 no hydrogen 3.015 N/A LYS 243.A NZ GLY 171.A O no hydrogen 2.913 N/A ALA 244.A N ASP 241.A O no hydrogen 3.192 N/A ARG 245.A N ASP 241.A O no hydrogen 2.963 N/A ARG 245.A NE VAL 239.A O no hydrogen 2.751 N/A ARG 245.A NH1 ALA 178.A O no hydrogen 2.881 N/A ARG 245.A NH2 VAL 239.A O no hydrogen 2.931 N/A PHE 246.A N LYS 236.A O no hydrogen 3.128 N/A THR 247.A N GLU 250.A OE1 no hydrogen 2.982 N/A THR 247.A OG1 GLU 250.A OE1 no hydrogen 3.544 N/A THR 248.A OG1 GLU 249.A OE1 no hydrogen 3.329 N/A GLU 250.A N THR 247.A OG1 no hydrogen 3.332 N/A ALA 251.A N THR 247.A O no hydrogen 3.028 N/A LEU 252.A N THR 248.A O no hydrogen 2.888 N/A ARG 253.A N GLU 249.A O no hydrogen 3.073 N/A ARG 253.A N GLU 250.A O no hydrogen 3.193 N/A HIS 254.A N ALA 251.A O no hydrogen 3.129 N/A HIS 254.A NE2 ASP 232.A OD2 no hydrogen 2.878 N/A TRP 256.A N HIS 254.A ND1 no hydrogen 2.954 N/A TRP 256.A NE1 GLU 94.A OE2 no hydrogen 2.741 N/A LEU 257.A N HIS 254.A O no hydrogen 2.954 N/A GLN 258.A N PRO 255.A O no hydrogen 3.092 N/A GLN 258.A NE2 LEU 252.A O no hydrogen 2.814 N/A GLN 258.A NE2 HIS 254.A O no hydrogen 2.892 N/A MET 262.A N ASP 259.A OD1 no hydrogen 2.762 N/A LYS 263.A N ASP 259.A O no hydrogen 3.198 N/A LYS 263.A NZ GLN 258.A OE1 no hydrogen 3.521 N/A ARG 264.A N GLU 260.A O no hydrogen 3.054 N/A ARG 264.A NH1 ASP 261.A OD1 no hydrogen 2.711 N/A ARG 264.A NH2 ASP 261.A OD1 no hydrogen 3.568 N/A LYS 265.A N ASP 261.A O no hydrogen 3.081 N/A PHE 266.A N MET 262.A O no hydrogen 2.965 N/A GLN 267.A N LYS 263.A O no hydrogen 3.038 N/A ASP 268.A N ARG 264.A O no hydrogen 2.899 N/A LEU 269.A N LYS 265.A O no hydrogen 3.016 N/A LEU 270.A N PHE 266.A O no hydrogen 2.945 N/A SER 271.A N GLN 267.A O no hydrogen 3.004 N/A SER 271.A OG GLN 267.A O no hydrogen 3.412 N/A SER 271.A OG ASP 268.A O no hydrogen 3.146 N/A GLU 272.A N ASP 268.A O no hydrogen 3.190 N/A GLU 273.A N LEU 269.A O no hydrogen 3.077 N/A ASN 274.A N LEU 270.A O no hydrogen 3.035 N/A GLU 275.A N SER 271.A O no hydrogen 2.867 N/A THR 277.A N ASN 274.A O no hydrogen 3.028 N/A THR 277.A OG1 ASN 274.A O no hydrogen 3.173 N/A ALA 284.A N VAL 282.A O no hydrogen 3.667 N/A