Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4c3x_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 3.A N ARG 216.A O no hydrogen 2.713 N/A THR 3.A OG1 ARG 216.A O no hydrogen 3.340 N/A SER 4.A N ARG 216.A O no hydrogen 3.459 N/A CYS 6.A N LYS 218.A O no hydrogen 2.813 N/A CYS 6.A SG LYS 218.A O no hydrogen 3.618 N/A ASP 7.A N THR 30.A OG1 no hydrogen 2.883 N/A VAL 8.A N THR 30.A O no hydrogen 2.950 N/A LEU 9.A N GLY 222.A O no hydrogen 2.992 N/A VAL 10.A N ILE 32.A O no hydrogen 2.774 N/A VAL 11.A N LEU 224.A O no hydrogen 2.806 N/A GLY 12.A N LEU 34.A O no hydrogen 2.789 N/A SER 13.A OG GLU 35.A OE1 no hydrogen 2.633 N/A GLY 15.A N SER 44.A OG no hydrogen 3.084 N/A LEU 18.A N GLY 14.A O no hydrogen 2.994 N/A THR 19.A N GLY 15.A O no hydrogen 2.976 N/A THR 19.A OG1 GLY 15.A O no hydrogen 2.820 N/A GLY 20.A N GLY 16.A O no hydrogen 2.873 N/A ALA 21.A N ALA 17.A O no hydrogen 2.866 N/A TYR 22.A N LEU 18.A O no hydrogen 2.861 N/A THR 23.A N THR 19.A O no hydrogen 2.942 N/A THR 23.A OG1 THR 19.A O no hydrogen 2.764 N/A ALA 24.A N GLY 20.A O no hydrogen 3.050 N/A ALA 25.A N ALA 21.A O no hydrogen 2.851 N/A ALA 26.A N TYR 22.A O no hydrogen 2.780 N/A GLN 27.A N ALA 24.A O no hydrogen 3.269 N/A GLN 27.A NE2 THR 23.A O no hydrogen 2.945 N/A GLN 27.A NE2 GLN 504.A OE1 no hydrogen 2.792 N/A GLY 28.A N ALA 25.A O no hydrogen 3.197 N/A LEU 29.A N ALA 24.A O no hydrogen 3.142 N/A THR 30.A N ASP 7.A OD2 no hydrogen 2.981 N/A THR 31.A N LYS 184.A O no hydrogen 2.896 N/A THR 31.A OG1 LEU 29.A O no hydrogen 3.055 N/A ILE 32.A N VAL 8.A O no hydrogen 3.103 N/A VAL 33.A N GLU 186.A O no hydrogen 2.802 N/A LEU 34.A N VAL 10.A O no hydrogen 2.861 N/A GLU 35.A N ARG 188.A O no hydrogen 2.796 N/A LYS 36.A NZ ALA 255.A O no hydrogen 2.724 N/A LYS 36.A NZ ASP 259.A OD2 no hydrogen 2.968 N/A THR 37.A N GLU 35.A OE2 no hydrogen 2.904 N/A THR 37.A OG1 GLU 35.A OE2 no hydrogen 2.812 N/A ARG 39.A N THR 37.A OG1 no hydrogen 3.147 N/A ARG 39.A NE VAL 147.A O no hydrogen 3.290 N/A ARG 39.A NH1 ASP 159.A OD2 no hydrogen 3.456 N/A ARG 39.A NH2 VAL 147.A O no hydrogen 3.173 N/A ARG 39.A NH2 ASP 159.A OD1 no hydrogen 2.597 N/A ARG 39.A NH2 ASP 159.A OD2 no hydrogen 3.422 N/A PHE 40.A N LYS 146.A O no hydrogen 2.775 N/A GLY 41.A N SER 13.A OG no hydrogen 2.938 N/A ALA 45.A N GLY 41.A O no hydrogen 3.042 N/A ALA 45.A N GLY 42.A O no hydrogen 3.094 N/A TYR 46.A OH ASP 154.A OD2 no hydrogen 2.486 N/A SER 47.A N SER 44.A O no hydrogen 3.180 N/A SER 47.A OG SER 44.A O no hydrogen 2.818 N/A ALA 49.A N SER 47.A OG no hydrogen 2.915 N/A ILE 51.A N ILE 130.A O no hydrogen 2.753 N/A TRP 52.A N GLY 489.A O no hydrogen 2.925 N/A TRP 52.A NE1 ASP 116.A OD1 no hydrogen 2.911 N/A LEU 53.A N ILE 51.A O no hydrogen 3.086 N/A THR 56.A N GLN 59.A OE1 no hydrogen 2.988 N/A THR 56.A OG1 GLN 59.A OE1 no hydrogen 2.694 N/A GLN 57.A NE2 GLU 102.A OE1 no hydrogen 2.847 N/A VAL 58.A N THR 56.A OG1 no hydrogen 3.102 N/A GLN 59.A N GLN 59.A OE1 no hydrogen 2.840 N/A GLN 59.A NE2 LEU 53.A O no hydrogen 2.769 N/A GLN 59.A NE2 ARG 128.A O no hydrogen 2.709 N/A GLU 60.A N THR 56.A O no hydrogen 3.157 N/A ARG 61.A N GLN 57.A O no hydrogen 3.100 N/A ARG 61.A NH1 GLU 102.A OE1 no hydrogen 2.776 N/A ARG 61.A NH2 GLU 102.A OE1 no hydrogen 3.469 N/A ARG 61.A NH2 GLU 102.A OE2 no hydrogen 2.882 N/A ALA 62.A N GLN 59.A O no hydrogen 3.116 N/A GLY 63.A N GLU 60.A O no hydrogen 2.953 N/A LEU 64.A N GLN 59.A O no hydrogen 3.123 N/A ASN 70.A N SER 67.A OG no hydrogen 3.167 N/A ASN 70.A ND2 ASP 66.A OD1 no hydrogen 2.782 N/A ALA 71.A N SER 67.A O no hydrogen 3.013 N/A ARG 72.A N THR 68.A O no hydrogen 2.856 N/A ARG 72.A NE GLU 69.A OE1 no hydrogen 2.926 N/A ARG 72.A NH1 ASP 88.A OD1 no hydrogen 2.854 N/A ARG 72.A NH1 GLU 92.A OE2 no hydrogen 2.733 N/A ARG 72.A NH2 GLU 69.A OE2 no hydrogen 2.728 N/A ARG 72.A NH2 GLU 92.A OE2 no hydrogen 3.461 N/A THR 73.A N GLU 69.A O no hydrogen 2.938 N/A THR 73.A OG1 GLU 69.A O no hydrogen 2.961 N/A TYR 74.A N ASN 70.A O no hydrogen 3.109 N/A TYR 74.A OH PRO 486.A O no hydrogen 2.646 N/A LEU 75.A N ALA 71.A O no hydrogen 3.095 N/A ARG 76.A N ARG 72.A O no hydrogen 2.963 N/A ARG 76.A NH1 ASP 88.A OD1 no hydrogen 2.565 N/A ARG 76.A NH2 ASP 88.A OD1 no hydrogen 3.489 N/A ALA 77.A N THR 73.A O no hydrogen 2.897 N/A LEU 78.A N TYR 74.A O no hydrogen 3.064 N/A LEU 79.A N LEU 75.A O no hydrogen 2.744 N/A GLY 80.A N ARG 76.A O no hydrogen 2.918 N/A SER 84.A N ASP 81.A O no hydrogen 2.978 N/A GLU 85.A N GLU 85.A OE1 no hydrogen 2.898 N/A ARG 86.A NH1 GLU 83.A OE1 no hydrogen 2.984 N/A ARG 86.A NH1 ALA 478.A O no hydrogen 3.563 N/A ARG 86.A NH2 ALA 478.A O no hydrogen 2.777 N/A GLN 87.A N GLU 83.A O no hydrogen 2.877 N/A GLN 87.A NE2 GLY 80.A O no hydrogen 2.897 N/A GLN 87.A NE2 ALA 82.A O no hydrogen 3.023 N/A ASP 88.A N SER 84.A O no hydrogen 2.918 N/A ALA 89.A N GLU 85.A O no hydrogen 2.956 N/A TYR 90.A N ARG 86.A O no hydrogen 2.925 N/A TYR 90.A OH TRP 52.A O no hydrogen 2.665 N/A VAL 91.A N GLN 87.A O no hydrogen 3.163 N/A GLU 92.A N ASP 88.A O no hydrogen 2.909 N/A THR 93.A N ALA 89.A O no hydrogen 3.011 N/A THR 93.A OG1 ALA 89.A O no hydrogen 2.620 N/A VAL 97.A N THR 93.A O no hydrogen 3.096 N/A VAL 98.A N ALA 94.A O no hydrogen 3.030 N/A ALA 99.A N PRO 95.A O no hydrogen 2.860 N/A LEU 100.A N ALA 96.A O no hydrogen 2.931 N/A LEU 101.A N VAL 97.A O no hydrogen 2.990 N/A GLU 102.A N VAL 98.A O no hydrogen 2.822 N/A GLN 103.A N ALA 99.A O no hydrogen 3.153 N/A GLN 103.A N LEU 100.A O no hydrogen 3.288 N/A ASN 104.A N LEU 101.A O no hydrogen 2.937 N/A ASN 104.A ND2 TYR 22.A OH no hydrogen 3.045 N/A ASN 104.A ND2 SER 181.A OG no hydrogen 3.219 N/A ASN 106.A N ASN 104.A OD1 no hydrogen 2.855 N/A ASN 106.A ND2 ASN 104.A OD1 no hydrogen 2.978 N/A ILE 107.A N ASN 104.A O no hydrogen 3.074 N/A PHE 109.A N GLU 102.A OE2 no hydrogen 2.894 N/A GLU 110.A N ASN 131.A O no hydrogen 2.793 N/A ARG 112.A N SER 129.A O no hydrogen 3.132 N/A ARG 112.A NE GLU 110.A OE2 no hydrogen 2.882 N/A ARG 112.A NH2 GLU 110.A OE2 no hydrogen 2.937 N/A PHE 114.A N THR 126.A O no hydrogen 2.843 N/A ASP 116.A N MET 124.A O no hydrogen 3.136 N/A TYR 117.A N PRO 486.A O no hydrogen 2.970 N/A TYR 117.A OH TYR 316.A OH no hydrogen 2.578 N/A TYR 118.A N TYR 74.A OH no hydrogen 3.052 N/A ARG 123.A N ALA 120.A O no hydrogen 3.056 N/A ARG 123.A NE ASP 116.A O no hydrogen 3.053 N/A ARG 123.A NH1 ASP 410.A OD1 no hydrogen 3.527 N/A ARG 123.A NH1 ASP 410.A OD2 no hydrogen 2.889 N/A ARG 123.A NH2 ASP 116.A O no hydrogen 2.822 N/A ARG 123.A NH2 ASP 410.A OD1 no hydrogen 2.836 N/A ARG 123.A NH2 ASP 410.A OD2 no hydrogen 3.492 N/A MET 124.A N ASP 116.A OD2 no hydrogen 2.991 N/A THR 126.A OG1 GLY 127.A O no hydrogen 3.450 N/A GLY 127.A N MET 124.A O no hydrogen 3.008 N/A ARG 128.A NE ASP 66.A OD2 no hydrogen 2.795 N/A ARG 128.A NH1 GLY 122.A O no hydrogen 2.966 N/A ARG 128.A NH2 ASP 66.A OD1 no hydrogen 2.775 N/A ARG 128.A NH2 GLY 122.A O no hydrogen 2.771 N/A SER 129.A OG PRO 488.A O no hydrogen 2.668 N/A ILE 130.A N ILE 51.A O no hydrogen 3.053 N/A ASN 131.A N GLU 110.A O no hydrogen 2.843 N/A ASN 131.A ND2 GLY 48.A O no hydrogen 3.261 N/A LEU 133.A N GLU 108.A O no hydrogen 3.033 N/A LEU 135.A N MET 165.A O no hydrogen 2.846 N/A ALA 138.A N ASP 136.A OD1 no hydrogen 2.929 N/A ASP 139.A N ASP 136.A O no hydrogen 2.800 N/A ILE 140.A N PRO 137.A O no hydrogen 3.288 N/A LEU 143.A N ILE 140.A O no hydrogen 3.171 N/A ALA 144.A N GLY 141.A O no hydrogen 3.426 N/A LYS 146.A N LEU 143.A O no hydrogen 2.936 N/A VAL 147.A N ALA 144.A O no hydrogen 3.150 N/A ARG 148.A N PHE 40.A O no hydrogen 2.971 N/A ARG 148.A NH1 ASP 154.A OD2 no hydrogen 2.841 N/A GLN 153.A N GLU 150.A O no hydrogen 2.908 N/A GLN 153.A NE2 ASP 159.A O no hydrogen 2.889 N/A ASP 154.A N GLU 150.A O no hydrogen 2.738 N/A ARG 155.A N LEU 151.A O no hydrogen 3.346 N/A ARG 155.A NH2 SER 249.A O no hydrogen 3.051 N/A ARG 155.A NH2 GLY 251.A O no hydrogen 2.896 N/A THR 156.A N GLN 153.A O no hydrogen 3.216 N/A THR 156.A OG1 ASP 152.A O no hydrogen 3.100 N/A THR 156.A OG1 GLN 153.A O no hydrogen 3.219 N/A THR 156.A OG1 GLN 158.A OE1 no hydrogen 2.733 N/A GLN 158.A N GLN 153.A O no hydrogen 3.018 N/A HIS 160.A N ASP 159.A OD1 no hydrogen 2.950 N/A MET 165.A N LEU 135.A O no hydrogen 2.766 N/A GLY 168.A N SER 47.A O no hydrogen 2.848 N/A ARG 169.A N ILE 166.A O no hydrogen 3.020 N/A ARG 169.A NH1 ALA 45.A O no hydrogen 2.897 N/A ALA 170.A N ILE 166.A O no hydrogen 3.410 N/A LEU 171.A N GLY 167.A O no hydrogen 2.978 N/A ILE 172.A N GLY 168.A O no hydrogen 2.953 N/A GLY 173.A N ARG 169.A O no hydrogen 2.879 N/A ARG 174.A N ALA 170.A O no hydrogen 2.927 N/A ARG 174.A NE LEU 133.A O no hydrogen 2.856 N/A ARG 174.A NH1 ASN 106.A O no hydrogen 2.846 N/A ARG 174.A NH2 LEU 133.A O no hydrogen 3.217 N/A ARG 174.A NH2 ASP 134.A O no hydrogen 2.928 N/A LEU 175.A N LEU 171.A O no hydrogen 2.951 N/A LEU 176.A N ILE 172.A O no hydrogen 2.879 N/A ALA 177.A N GLY 173.A O no hydrogen 3.069 N/A ALA 178.A N ARG 174.A O no hydrogen 2.936 N/A VAL 179.A N LEU 175.A O no hydrogen 2.852 N/A GLN 180.A N LEU 176.A O no hydrogen 2.879 N/A SER 181.A N ALA 177.A O no hydrogen 2.900 N/A SER 181.A OG ALA 178.A O no hydrogen 2.698 N/A THR 182.A N VAL 179.A O no hydrogen 3.309 N/A THR 182.A OG1 VAL 179.A O no hydrogen 2.834 N/A GLY 183.A N GLN 180.A O no hydrogen 3.179 N/A LYS 184.A N THR 182.A OG1 no hydrogen 3.009 N/A GLU 186.A N THR 31.A O no hydrogen 2.853 N/A ARG 188.A N VAL 33.A O no hydrogen 2.802 N/A ARG 188.A NE GLU 186.A OE2 no hydrogen 2.663 N/A ARG 188.A NH2 SER 4.A OG no hydrogen 3.377 N/A ARG 188.A NH2 GLU 186.A OE2 no hydrogen 2.928 N/A GLU 190.A N THR 37.A O no hydrogen 2.868 N/A SER 191.A N GLU 35.A O no hydrogen 2.901 N/A SER 191.A OG THR 189.A O no hydrogen 2.962 N/A VAL 192.A N GLU 209.A O no hydrogen 2.874 N/A THR 194.A N GLU 207.A O no hydrogen 2.935 N/A THR 194.A OG1 GLU 207.A O no hydrogen 2.950 N/A SER 195.A N GLU 207.A O no hydrogen 3.407 N/A ILE 197.A N GLY 205.A O no hydrogen 2.922 N/A GLU 199.A N ARG 202.A O no hydrogen 2.823 N/A ARG 202.A N GLU 199.A O no hydrogen 3.008 N/A ARG 202.A NH1 ASP 468.A OD2 no hydrogen 2.881 N/A ARG 202.A NH2 ASN 220.A O no hydrogen 3.403 N/A VAL 203.A N ASP 468.A O no hydrogen 2.890 N/A VAL 204.A N ILE 197.A O no hydrogen 2.815 N/A ALA 206.A N ILE 217.A O no hydrogen 2.880 N/A GLU 207.A N SER 195.A O no hydrogen 2.702 N/A VAL 208.A N GLN 215.A O no hydrogen 2.833 N/A GLU 209.A N VAL 192.A O no hydrogen 2.894 N/A SER 210.A N GLU 213.A O no hydrogen 3.040 N/A GLU 213.A N SER 210.A O no hydrogen 3.074 N/A GLN 215.A N VAL 208.A O no hydrogen 2.636 N/A GLN 215.A NE2 GLU 213.A OE2 no hydrogen 3.168 N/A ARG 216.A N THR 3.A OG1 no hydrogen 2.928 N/A ILE 217.A N ALA 206.A O no hydrogen 2.874 N/A LYS 218.A N SER 4.A O no hydrogen 2.841 N/A LYS 218.A NZ ASN 220.A OD1 no hydrogen 3.401 N/A ALA 219.A N VAL 204.A O no hydrogen 2.887 N/A ASN 220.A N CYS 6.A O no hydrogen 2.824 N/A ASN 220.A ND2 GLU 5.A OE2 no hydrogen 3.389 N/A ASN 220.A ND2 ASP 7.A OD1 no hydrogen 3.362 N/A ARG 221.A N ASP 7.A O no hydrogen 2.739 N/A ARG 221.A NH1 MET 506.A O no hydrogen 2.799 N/A ARG 221.A NH1 ALA 507.A O no hydrogen 3.297 N/A GLY 222.A N ASP 7.A O no hydrogen 3.291 N/A VAL 223.A N GLY 469.A O no hydrogen 2.845 N/A LEU 224.A N LEU 9.A O no hydrogen 2.765 N/A MET 225.A N TYR 471.A O no hydrogen 2.708 N/A ALA 226.A N VAL 11.A O no hydrogen 2.886 N/A ALA 227.A N THR 476.A OG1 no hydrogen 2.914 N/A ILE 230.A N THR 447.A OG1 no hydrogen 2.966 N/A GLU 231.A N GLU 231.A OE1 no hydrogen 2.922 N/A GLY 232.A N ASN 256.A O no hydrogen 2.798 N/A ASN 233.A N ILE 230.A O no hydrogen 2.817 N/A ASN 233.A ND2 THR 257.A O no hydrogen 3.002 N/A MET 236.A N ASN 233.A OD1 no hydrogen 2.861 N/A ARG 237.A N ASN 233.A O no hydrogen 3.014 N/A ARG 237.A NH1 GLU 231.A O no hydrogen 2.947 N/A ARG 237.A NH1 ASP 444.A OD2 no hydrogen 2.819 N/A ARG 237.A NH2 PRO 243.A O no hydrogen 2.721 N/A ARG 237.A NH2 ASP 444.A OD2 no hydrogen 3.346 N/A GLU 238.A N ALA 234.A O no hydrogen 2.873 N/A GLN 239.A N GLU 235.A O no hydrogen 2.884 N/A ALA 240.A N MET 236.A O no hydrogen 2.841 N/A GLY 241.A N GLU 238.A O no hydrogen 3.158 N/A THR 242.A N ARG 237.A O no hydrogen 2.910 N/A THR 242.A OG1 ARG 237.A O no hydrogen 3.341 N/A THR 242.A OG1 LEU 274.A O no hydrogen 2.811 N/A TRP 248.A N LYS 245.A O no hydrogen 2.947 N/A SER 249.A N ALA 246.A O no hydrogen 3.048 N/A SER 249.A OG ASP 444.A OD1 no hydrogen 2.714 N/A MET 250.A N ASP 444.A O no hydrogen 2.925 N/A GLY 251.A N SER 249.A OG no hydrogen 3.266 N/A ALA 255.A N PRO 252.A O no hydrogen 3.045 N/A ASN 256.A ND2 GLU 231.A OE2 no hydrogen 2.816 N/A THR 257.A OG1 ASP 259.A OD1 no hydrogen 2.743 N/A THR 257.A OG1 ASP 259.A OD2 no hydrogen 3.557 N/A SER 262.A N GLY 258.A O no hydrogen 2.946 N/A SER 262.A OG GLY 258.A O no hydrogen 3.186 N/A ALA 263.A N ASP 259.A O no hydrogen 2.948 N/A GLY 264.A N ALA 260.A O no hydrogen 2.931 N/A ILE 265.A N ILE 261.A O no hydrogen 2.914 N/A ALA 266.A N SER 262.A O no hydrogen 2.990 N/A VAL 267.A N GLY 264.A O no hydrogen 3.121 N/A GLY 268.A N ILE 265.A O no hydrogen 2.974 N/A GLY 269.A N GLY 264.A O no hydrogen 2.914 N/A ALA 270.A N LEU 460.A O no hydrogen 2.841 N/A ALA 272.A N GLY 450.A O no hydrogen 2.869 N/A GLN 276.A N LEU 273.A O no hydrogen 2.888 N/A GLN 276.A NE2 ASP 275.A OD1 no hydrogen 3.289 N/A TRP 278.A N GLY 446.A O no hydrogen 2.972 N/A TRP 278.A NE1 ASN 475.A OD1 no hydrogen 2.891 N/A PHE 279.A N ASP 317.A OD1 no hydrogen 2.872 N/A CYS 280.A N SER 443.A O no hydrogen 3.136 N/A CYS 280.A SG PRO 281.A O no hydrogen 3.849 N/A CYS 280.A SG SER 443.A OG no hydrogen 3.556 N/A GLY 282.A N VAL 441.A O no hydrogen 2.862 N/A VAL 283.A N ALA 291.A O no hydrogen 2.817 N/A GLU 284.A N ARG 439.A O no hydrogen 3.031 N/A GLN 285.A N SER 289.A O no hydrogen 2.818 N/A GLN 285.A NE2 VAL 283.A O no hydrogen 2.887 N/A GLY 288.A N GLN 285.A O no hydrogen 2.943 N/A SER 289.A N ASP 287.A OD1 no hydrogen 2.899 N/A SER 289.A OG ASP 287.A OD1 no hydrogen 2.586 N/A ALA 291.A N VAL 283.A O no hydrogen 3.035 N/A PHE 292.A N ILE 352.A O no hydrogen 2.817 N/A MET 293.A N PRO 281.A O no hydrogen 3.117 N/A VAL 294.A N ILE 350.A O no hydrogen 2.824 N/A ARG 297.A N PRO 348.A O no hydrogen 2.942 N/A ARG 297.A NE GLU 343.A OE2 no hydrogen 3.042 N/A ARG 297.A NH2 GLU 343.A OE1 no hydrogen 2.745 N/A LEU 300.A N ILE 338.A O no hydrogen 3.054 N/A VAL 301.A N GLU 312.A OE2 no hydrogen 2.912 N/A VAL 302.A N PHE 336.A O no hydrogen 2.871 N/A ASP 303.A N GLU 307.A O no hydrogen 3.001 N/A SER 304.A N SER 331.A O no hydrogen 2.878 N/A SER 304.A OG SER 331.A O no hydrogen 3.328 N/A GLY 306.A N ASP 303.A O no hydrogen 2.912 N/A GLU 307.A N ASP 303.A OD1 no hydrogen 3.083 N/A ARG 308.A NE GLU 312.A OE2 no hydrogen 2.903 N/A ARG 308.A NH1 ASP 402.A OD1 no hydrogen 2.984 N/A ARG 308.A NH1 ASP 402.A OD2 no hydrogen 3.372 N/A ARG 308.A NH2 GLU 312.A OE1 no hydrogen 2.826 N/A ARG 308.A NH2 ASP 402.A OD2 no hydrogen 2.918 N/A TYR 309.A OH SER 335.A OG no hydrogen 2.719 N/A ASN 311.A ND2 ASP 413.A OD2 no hydrogen 3.086 N/A GLU 312.A N GLU 312.A OE1 no hydrogen 2.819 N/A SER 313.A N ASN 311.A OD1 no hydrogen 2.839 N/A LEU 314.A N ASN 311.A O no hydrogen 3.054 N/A TYR 316.A OH TYR 117.A OH no hydrogen 2.578 N/A PHE 319.A N PRO 315.A O no hydrogen 2.934 N/A GLY 320.A N TYR 316.A O no hydrogen 2.888 N/A ARG 321.A N ASP 317.A O no hydrogen 2.923 N/A ARG 321.A NE ASP 317.A OD2 no hydrogen 2.795 N/A ARG 321.A NH1 GLN 276.A OE1 no hydrogen 2.807 N/A ARG 321.A NH2 GLN 276.A OE1 no hydrogen 2.844 N/A ALA 322.A N GLN 318.A O no hydrogen 2.981 N/A MET 323.A N PHE 319.A O no hydrogen 3.027 N/A ASP 324.A N GLY 320.A O no hydrogen 3.039 N/A ALA 325.A N ARG 321.A O no hydrogen 2.907 N/A HIS 326.A N ALA 322.A O no hydrogen 3.037 N/A HIS 326.A N MET 323.A O no hydrogen 3.176 N/A HIS 326.A NE2 ASP 303.A OD2 no hydrogen 2.769 N/A ASP 327.A N ASP 324.A O no hydrogen 3.269 N/A ASP 328.A N SER 331.A OG no hydrogen 2.826 N/A SER 331.A N ASP 328.A O no hydrogen 3.305 N/A SER 331.A OG ASP 328.A O no hydrogen 3.395 N/A ALA 332.A N ASP 327.A OD1 no hydrogen 2.835 N/A VAL 333.A N ASP 327.A OD1 no hydrogen 3.009 N/A SER 335.A N ILE 440.A O no hydrogen 2.826 N/A SER 335.A OG TYR 309.A OH no hydrogen 2.719 N/A SER 335.A OG ALA 332.A O no hydrogen 2.693 N/A PHE 336.A N VAL 302.A O no hydrogen 2.863 N/A MET 337.A N ALA 438.A O no hydrogen 2.866 N/A ILE 338.A N LEU 300.A O no hydrogen 2.815 N/A PHE 339.A N TYR 436.A O no hydrogen 2.968 N/A SER 341.A N ASN 432.A O no hydrogen 2.896 N/A SER 341.A OG PRO 434.A O no hydrogen 2.802 N/A ARG 342.A N ASP 340.A OD1 no hydrogen 2.957 N/A GLY 344.A N SER 341.A O no hydrogen 2.791 N/A GLY 346.A N GLU 343.A O no hydrogen 3.087 N/A ALA 349.A N LEU 347.A O no hydrogen 2.874 N/A ILE 350.A N VAL 294.A O no hydrogen 2.783 N/A ILE 352.A N PHE 292.A O no hydrogen 2.792 N/A ASN 354.A N ASP 152.A OD1 no hydrogen 2.841 N/A THR 355.A OG1 GLN 285.A OE1 no hydrogen 2.556 N/A LYS 359.A N ALA 356.A O no hydrogen 2.959 N/A HIS 360.A N ALA 356.A O no hydrogen 3.438 N/A HIS 360.A ND1 THR 365.A OG1 no hydrogen 2.847 N/A LEU 361.A N PRO 357.A O no hydrogen 2.927 N/A GLU 362.A N ALA 358.A O no hydrogen 2.982 N/A ALA 363.A N LYS 359.A O no hydrogen 2.969 N/A GLY 364.A N HIS 360.A O no hydrogen 2.780 N/A GLY 364.A N LEU 361.A O no hydrogen 3.296 N/A THR 365.A OG1 HIS 360.A ND1 no hydrogen 2.847 N/A THR 365.A OG1 HIS 360.A O no hydrogen 3.211 N/A TRP 366.A N HIS 360.A O no hydrogen 3.329 N/A VAL 367.A N ALA 437.A O no hydrogen 3.001 N/A ALA 369.A N PHE 435.A O no hydrogen 2.910 N/A GLU 374.A N THR 371.A OG1 no hydrogen 3.181 N/A LEU 375.A N THR 371.A O no hydrogen 3.015 N/A ALA 376.A N LEU 372.A O no hydrogen 2.936 N/A ALA 377.A N GLU 373.A O no hydrogen 3.188 N/A LYS 378.A N GLU 374.A O no hydrogen 3.060 N/A LYS 378.A NZ GLY 368.A O no hydrogen 2.846 N/A LYS 378.A NZ GLU 374.A OE2 no hydrogen 3.404 N/A THR 379.A N ALA 376.A O no hydrogen 3.182 N/A THR 379.A OG1 LEU 375.A O no hydrogen 2.999 N/A THR 379.A OG1 ALA 376.A O no hydrogen 3.168 N/A LEU 381.A N THR 379.A OG1 no hydrogen 3.372 N/A LEU 386.A N PRO 382.A O no hydrogen 2.973 N/A ARG 387.A N ALA 383.A O no hydrogen 2.947 N/A ARG 387.A NE GLU 373.A OE2 no hydrogen 2.392 N/A ARG 387.A NH1 GLU 391.A OE2 no hydrogen 3.301 N/A ARG 387.A NH2 GLU 373.A OE1 no hydrogen 2.938 N/A ARG 387.A NH2 GLU 373.A OE2 no hydrogen 2.687 N/A SER 388.A N ASP 384.A O no hydrogen 2.944 N/A THR 389.A N ALA 385.A O no hydrogen 2.772 N/A THR 389.A OG1 GLY 306.A O no hydrogen 2.744 N/A THR 389.A OG1 ALA 385.A O no hydrogen 3.029 N/A VAL 390.A N LEU 386.A O no hydrogen 2.938 N/A GLU 391.A N ARG 387.A O no hydrogen 2.942 N/A LYS 392.A N SER 388.A O no hydrogen 2.966 N/A LYS 392.A NZ GLU 404.A OE1 no hydrogen 2.908 N/A PHE 393.A N THR 389.A O no hydrogen 2.965 N/A ASN 394.A N VAL 390.A O no hydrogen 2.771 N/A ASN 394.A ND2 ILE 430.A O no hydrogen 2.901 N/A ASP 395.A N GLU 391.A O no hydrogen 2.951 N/A ALA 396.A N LYS 392.A O no hydrogen 3.042 N/A ALA 397.A N PHE 393.A O no hydrogen 2.842 N/A LYS 398.A N ASN 394.A O no hydrogen 2.983 N/A LEU 399.A N ASP 395.A O no hydrogen 2.989 N/A GLY 400.A N ALA 396.A O no hydrogen 2.702 N/A GLY 400.A N ALA 397.A O no hydrogen 3.218 N/A VAL 401.A N ALA 396.A O no hydrogen 3.146 N/A GLU 404.A N ASP 402.A OD1 no hydrogen 3.137 N/A PHE 405.A N ASP 402.A OD1 no hydrogen 3.023 N/A HIS 406.A N ASP 402.A O no hydrogen 2.803 N/A HIS 406.A ND1 GLU 409.A OE2 no hydrogen 3.241 N/A ARG 407.A N ASP 402.A OD2 no hydrogen 3.011 N/A ARG 407.A NE SER 313.A OG no hydrogen 2.953 N/A ARG 407.A NH1 GLY 299.A O no hydrogen 2.787 N/A ARG 407.A NH1 GLU 312.A OE1 no hydrogen 2.935 N/A ARG 407.A NH2 GLY 298.A O no hydrogen 3.189 N/A ARG 407.A NH2 GLY 299.A O no hydrogen 3.240 N/A GLY 408.A N ASP 413.A OD2 no hydrogen 2.897 N/A TYR 412.A N ASP 410.A OD1 no hydrogen 2.829 N/A ALA 414.A N ASP 410.A O no hydrogen 3.310 N/A PHE 415.A N PRO 411.A O no hydrogen 3.041 N/A PHE 415.A N TYR 412.A O no hydrogen 3.224 N/A CYS 417.A N ALA 414.A O no hydrogen 3.161 N/A CYS 417.A SG ASP 413.A O no hydrogen 3.438 N/A CYS 417.A SG ALA 425.A O no hydrogen 3.524 N/A ASN 424.A ND2 GLY 400.A O no hydrogen 3.350 N/A ASN 424.A ND2 GLY 408.A O no hydrogen 3.006 N/A ALA 426.A N ASN 424.A OD1 no hydrogen 2.922 N/A LEU 427.A N ASN 424.A O no hydrogen 2.996 N/A ILE 430.A N ASN 394.A OD1 no hydrogen 2.742 N/A GLU 431.A N ASP 340.A OD2 no hydrogen 2.899 N/A ASN 432.A N ASP 340.A OD2 no hydrogen 2.949 N/A PHE 435.A N ALA 369.A O no hydrogen 2.843 N/A TYR 436.A N PHE 339.A O no hydrogen 2.767 N/A ALA 437.A N VAL 367.A O no hydrogen 2.945 N/A ALA 438.A N MET 337.A O no hydrogen 2.883 N/A ARG 439.A N THR 365.A O no hydrogen 3.252 N/A ARG 439.A NE GLU 284.A OE1 no hydrogen 2.773 N/A ILE 440.A N SER 335.A O no hydrogen 2.769 N/A VAL 441.A N GLY 282.A O no hydrogen 2.769 N/A SER 443.A N CYS 280.A O no hydrogen 2.763 N/A SER 443.A OG TRP 248.A O no hydrogen 2.661 N/A SER 443.A OG ASP 444.A O no hydrogen 3.551 N/A LEU 445.A N TRP 278.A O no hydrogen 2.729 N/A GLY 446.A N ASP 444.A OD1 no hydrogen 2.826 N/A THR 447.A N GLU 231.A OE1 no hydrogen 3.177 N/A THR 447.A OG1 GLU 231.A OE1 no hydrogen 3.128 N/A LYS 448.A N GLN 276.A O no hydrogen 3.184 N/A LYS 448.A NZ SER 481.A OG no hydrogen 2.829 N/A LYS 448.A NZ GLY 482.A O no hydrogen 2.640 N/A LYS 448.A NZ PHE 484.A O no hydrogen 2.867 N/A GLY 450.A N ALA 272.A O no hydrogen 2.885 N/A LEU 451.A N THR 476.A O no hydrogen 3.005 N/A VAL 452.A N ALA 270.A O no hydrogen 2.909 N/A ASP 454.A N ARG 458.A O no hydrogen 3.097 N/A ASN 456.A N ASP 454.A OD1 no hydrogen 2.807 N/A GLY 457.A N ASP 454.A O no hydrogen 2.970 N/A ARG 458.A N ASP 454.A OD1 no hydrogen 3.029 N/A ARG 458.A NH1 ASP 454.A OD2 no hydrogen 3.316 N/A VAL 459.A N LEU 470.A O no hydrogen 2.993 N/A LEU 460.A N VAL 452.A O no hydrogen 2.913 N/A ARG 461.A N SER 465.A O no hydrogen 2.792 N/A ARG 461.A NH1 SER 465.A OG no hydrogen 2.881 N/A ARG 461.A NH1 ALA 466.A O no hydrogen 3.321 N/A GLY 464.A N ARG 461.A O no hydrogen 2.858 N/A SER 465.A N ASP 463.A OD1 no hydrogen 2.912 N/A SER 465.A OG ASP 463.A OD1 no hydrogen 2.537 N/A SER 465.A OG ASP 463.A OD2 no hydrogen 3.501 N/A ILE 467.A N VAL 459.A O no hydrogen 2.836 N/A LEU 470.A N ILE 467.A O no hydrogen 3.153 N/A TYR 471.A N VAL 223.A O no hydrogen 2.791 N/A TYR 471.A OH ASP 505.A OD2 no hydrogen 2.487 N/A ALA 472.A N GLY 457.A O no hydrogen 2.894 N/A ALA 473.A N MET 225.A O no hydrogen 3.144 N/A THR 476.A OG1 GLY 228.A O no hydrogen 2.734 N/A SER 477.A N GLY 474.A O no hydrogen 2.958 N/A SER 477.A OG GLY 474.A O no hydrogen 2.817 N/A ALA 478.A N LEU 451.A O no hydrogen 2.904 N/A SER 479.A N LYS 448.A O no hydrogen 2.934 N/A SER 479.A OG SER 481.A OG no hydrogen 2.777 N/A SER 481.A N SER 479.A OG no hydrogen 3.155 N/A SER 481.A OG SER 479.A OG no hydrogen 2.777 N/A SER 481.A OG PHE 484.A O no hydrogen 3.147 N/A GLY 482.A N SER 479.A O no hydrogen 3.282 N/A PHE 484.A N SER 481.A O no hydrogen 2.985 N/A GLY 493.A N GLY 489.A O no hydrogen 2.824 N/A THR 494.A N VAL 490.A O no hydrogen 2.921 N/A THR 494.A OG1 VAL 490.A O no hydrogen 2.851 N/A THR 494.A OG1 PRO 491.A O no hydrogen 3.154 N/A ALA 495.A N PRO 491.A O no hydrogen 3.227 N/A MET 496.A N LEU 492.A O no hydrogen 2.865 N/A VAL 497.A N GLY 493.A O no hydrogen 2.972 N/A PHE 498.A N THR 494.A O no hydrogen 3.068 N/A SER 499.A N ALA 495.A O no hydrogen 3.073 N/A SER 499.A OG ALA 495.A O no hydrogen 2.827 N/A TYR 500.A N MET 496.A O no hydrogen 3.077 N/A ARG 501.A N VAL 497.A O no hydrogen 2.901 N/A ARG 501.A NE VAL 455.A O no hydrogen 2.770 N/A ARG 501.A NE ASN 456.A OD1 no hydrogen 3.272 N/A ARG 501.A NH1 THR 93.A OG1 no hydrogen 2.873 N/A ARG 501.A NH2 ASN 456.A OD1 no hydrogen 2.804 N/A ALA 502.A N PHE 498.A O no hydrogen 2.908 N/A ALA 503.A N SER 499.A O no hydrogen 3.073 N/A GLN 504.A N TYR 500.A O no hydrogen 2.910 N/A ASP 505.A N ARG 501.A O no hydrogen 2.883 N/A MET 506.A N ALA 502.A O no hydrogen 2.969 N/A ALA 507.A N ALA 503.A O no hydrogen 3.059 N/A ALA 507.A N GLN 504.A O no hydrogen 3.109 N/A LYS 508.A N ASP 505.A O no hydrogen 3.190 N/A LYS 508.A NZ ASP 505.A OD1 no hydrogen 2.821 N/A