Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4c4i_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 2.A OG TYR 10.A O no hydrogen 3.100 N/A MET 3.A N TYR 10.A O no hydrogen 2.920 N/A SER 4.A OG ARG 8.A O no hydrogen 3.476 N/A VAL 5.A N ARG 8.A O no hydrogen 3.054 N/A LYS 6.A N GLU 77.A OE2 no hydrogen 2.897 N/A LYS 6.A NZ TYR 76.A O no hydrogen 2.763 N/A ARG 8.A N VAL 5.A O no hydrogen 3.129 N/A TYR 10.A N MET 3.A O no hydrogen 2.781 N/A SER 11.A N LEU 28.A O no hydrogen 2.820 N/A ILE 12.A N GLN 1.A O no hydrogen 3.035 N/A LEU 13.A N GLN 26.A O no hydrogen 2.769 N/A LYS 14.A N GLN 26.A O no hydrogen 3.417 N/A ILE 16.A N VAL 24.A O no hydrogen 2.800 N/A GLY 17.A N VAL 24.A O no hydrogen 3.410 N/A LYS 23.A N TYR 39.A O no hydrogen 2.812 N/A VAL 24.A N GLY 17.A O no hydrogen 2.809 N/A PHE 25.A N ILE 37.A O no hydrogen 2.882 N/A GLN 26.A N LYS 14.A O no hydrogen 2.756 N/A VAL 27.A N TYR 35.A O no hydrogen 3.015 N/A LEU 28.A N SER 11.A O no hydrogen 2.805 N/A ASN 29.A N GLN 33.A O no hydrogen 2.874 N/A LYS 31.A N ASN 29.A OD1 no hydrogen 2.987 N/A LYS 32.A N ASN 29.A O no hydrogen 3.007 N/A GLN 33.A N ASN 29.A OD1 no hydrogen 2.778 N/A TYR 35.A N VAL 27.A O no hydrogen 3.086 N/A TYR 35.A OH GLN 33.A OE1 no hydrogen 2.719 N/A ALA 36.A N MET 87.A O no hydrogen 3.021 N/A ILE 37.A N PHE 25.A O no hydrogen 2.896 N/A LYS 38.A N MET 85.A O no hydrogen 3.036 N/A TYR 39.A N LYS 23.A O no hydrogen 2.730 N/A VAL 40.A N ILE 83.A O no hydrogen 2.887 N/A ASN 41.A N SER 21.A O no hydrogen 3.371 N/A LEU 42.A N GLN 81.A O no hydrogen 2.753 N/A GLU 43.A N ASN 41.A OD1 no hydrogen 3.179 N/A ALA 45.A N LEU 42.A O no hydrogen 3.177 N/A THR 49.A N ASP 46.A OD1 no hydrogen 3.106 N/A THR 49.A OG1 ASP 46.A OD1 no hydrogen 2.870 N/A THR 49.A OG1 ASP 46.A OD2 no hydrogen 2.714 N/A LEU 50.A N ASP 46.A O no hydrogen 2.800 N/A ASP 51.A N ASN 47.A O no hydrogen 2.960 N/A SER 52.A N GLN 48.A O no hydrogen 2.901 N/A SER 52.A OG THR 49.A O no hydrogen 3.084 N/A TYR 53.A N THR 49.A O no hydrogen 3.053 N/A ARG 54.A N LEU 50.A O no hydrogen 2.911 N/A ARG 54.A NH1 ASP 51.A OD1 no hydrogen 3.442 N/A ASN 55.A N ASP 51.A O no hydrogen 2.836 N/A GLU 56.A N SER 52.A O no hydrogen 3.171 N/A ILE 57.A N TYR 53.A O no hydrogen 3.253 N/A ALA 58.A N ARG 54.A O no hydrogen 3.105 N/A TYR 59.A N ASN 55.A O no hydrogen 3.125 N/A LEU 60.A N GLU 56.A O no hydrogen 2.865 N/A ASN 61.A N ILE 57.A O no hydrogen 2.956 N/A LYS 62.A N ALA 58.A O no hydrogen 2.942 N/A LEU 63.A N TYR 59.A O no hydrogen 2.895 N/A GLN 64.A NE2 LEU 60.A O no hydrogen 2.750 N/A GLN 64.A NE2 ILE 71.A O no hydrogen 2.866 N/A GLN 65.A NE2 ASN 61.A O no hydrogen 3.078 N/A HIS 66.A N LEU 63.A O no hydrogen 3.154 N/A HIS 66.A ND1 LYS 62.A O no hydrogen 3.062 N/A SER 67.A N LEU 63.A O no hydrogen 3.280 N/A SER 67.A OG GLU 118.A OE2 no hydrogen 3.171 N/A LYS 69.A N SER 67.A OG no hydrogen 3.390 N/A LYS 69.A NZ ASP 68.A OD1 no hydrogen 2.892 N/A LYS 69.A NZ GLU 118.A OE1 no hydrogen 3.005 N/A ILE 71.A N LEU 147.A O no hydrogen 3.267 N/A ARG 72.A N GLU 88.A OE2 no hydrogen 2.860 N/A ARG 72.A NE ILE 70.A O no hydrogen 3.368 N/A ARG 72.A NH1 GLN 64.A O no hydrogen 3.084 N/A ARG 72.A NH2 GLN 64.A O no hydrogen 3.268 N/A ARG 72.A NH2 SER 67.A O no hydrogen 2.641 N/A ARG 72.A NH2 ILE 70.A O no hydrogen 2.787 N/A LEU 73.A N GLN 64.A OE1 no hydrogen 2.896 N/A TYR 74.A N VAL 86.A O no hydrogen 2.687 N/A ASP 75.A N VAL 86.A O no hydrogen 3.386 N/A GLU 77.A N TYR 84.A O no hydrogen 2.808 N/A THR 79.A N TYR 82.A O no hydrogen 3.018 N/A THR 79.A OG1 GLN 81.A OE1 no hydrogen 3.500 N/A THR 79.A OG1 TYR 82.A O no hydrogen 3.425 N/A GLN 81.A N THR 79.A OG1 no hydrogen 3.346 N/A TYR 82.A N THR 79.A OG1 no hydrogen 3.275 N/A ILE 83.A N VAL 40.A O no hydrogen 2.890 N/A TYR 84.A N GLU 77.A O no hydrogen 2.780 N/A MET 85.A N LYS 38.A O no hydrogen 2.826 N/A VAL 86.A N ASP 75.A O no hydrogen 2.786 N/A MET 87.A N ALA 36.A O no hydrogen 2.938 N/A GLU 88.A N ARG 72.A O no hydrogen 3.106 N/A CYS 89.A SG GLY 90.A O no hydrogen 3.886 N/A ASN 91.A N ILE 140.A O no hydrogen 2.820 N/A LEU 94.A N PHE 138.A O no hydrogen 2.793 N/A SER 96.A N ASP 93.A OD2 no hydrogen 2.947 N/A SER 96.A OG ASP 93.A OD1 no hydrogen 2.911 N/A SER 96.A OG ASP 93.A OD2 no hydrogen 3.329 N/A TRP 97.A N ASP 93.A O no hydrogen 3.071 N/A LEU 98.A N LEU 94.A O no hydrogen 2.901 N/A LYS 99.A N ASN 95.A O no hydrogen 3.072 N/A LYS 100.A N SER 96.A O no hydrogen 3.340 N/A LYS 101.A N TRP 97.A O no hydrogen 2.812 N/A TRP 107.A N ASP 105.A OD1 no hydrogen 3.399 N/A ARG 109.A N ASP 105.A O no hydrogen 3.070 N/A ARG 109.A NH1 MET 186.A O no hydrogen 2.811 N/A ARG 109.A NH2 GLU 220.A OE2 no hydrogen 2.887 N/A LYS 110.A N PRO 106.A O no hydrogen 3.213 N/A LYS 110.A NZ TYR 249.A O no hydrogen 2.881 N/A LYS 110.A NZ ILE 252.A O no hydrogen 3.006 N/A SER 111.A N TRP 107.A O no hydrogen 3.062 N/A TYR 112.A N GLU 108.A O no hydrogen 2.823 N/A TYR 112.A OH GLU 108.A OE2 no hydrogen 2.909 N/A TRP 113.A N ARG 109.A O no hydrogen 2.830 N/A LYS 114.A N LYS 110.A O no hydrogen 2.947 N/A ASN 115.A N SER 111.A O no hydrogen 3.161 N/A MET 116.A N TYR 112.A O no hydrogen 2.962 N/A LEU 117.A N TRP 113.A O no hydrogen 3.095 N/A GLU 118.A N LYS 114.A O no hydrogen 2.961 N/A ALA 119.A N ASN 115.A O no hydrogen 3.004 N/A VAL 120.A N MET 116.A O no hydrogen 2.933 N/A HIS 121.A N LEU 117.A O no hydrogen 2.762 N/A THR 122.A N GLU 118.A O no hydrogen 3.038 N/A THR 122.A OG1 GLU 118.A O no hydrogen 2.675 N/A ILE 123.A N ALA 119.A O no hydrogen 3.346 N/A HIS 124.A N VAL 120.A O no hydrogen 3.185 N/A HIS 124.A NE2 ASP 175.A OD2 no hydrogen 2.759 N/A GLN 125.A N HIS 121.A O no hydrogen 3.050 N/A HIS 126.A N ILE 123.A O no hydrogen 3.188 N/A HIS 126.A ND1 THR 122.A O no hydrogen 2.841 N/A GLY 127.A N HIS 124.A O no hydrogen 2.741 N/A ILE 128.A N ILE 123.A O no hydrogen 2.757 N/A HIS 130.A N ASP 175.A OD2 no hydrogen 3.090 N/A HIS 130.A NE2 ASP 149.A OD1 no hydrogen 3.302 N/A SER 131.A N ASP 175.A OD1 no hydrogen 2.845 N/A SER 131.A OG HIS 130.A O no hydrogen 2.286 N/A ASP 132.A N HIS 130.A ND1 no hydrogen 2.938 N/A ASN 137.A N LYS 134.A O no hydrogen 3.200 N/A PHE 138.A N PRO 135.A O no hydrogen 3.005 N/A LEU 139.A N LYS 146.A O no hydrogen 2.749 N/A ILE 140.A N ILE 92.A O no hydrogen 2.795 N/A VAL 141.A N MET 144.A O no hydrogen 2.790 N/A ASP 142.A N ASN 91.A OD1 no hydrogen 3.196 N/A MET 144.A N VAL 141.A O no hydrogen 3.171 N/A LEU 145.A N ASN 115.A OD1 no hydrogen 2.842 N/A LYS 146.A N LEU 139.A O no hydrogen 2.795 N/A LYS 146.A NZ ASP 68.A O no hydrogen 2.774 N/A LYS 146.A NZ GLU 88.A OE2 no hydrogen 3.015 N/A LEU 147.A N LYS 69.A O no hydrogen 2.824 N/A ILE 148.A N ASN 137.A O no hydrogen 2.708 N/A PHE 150.A N GLU 56.A OE2 no hydrogen 2.795 N/A ALA 153.A N GLU 56.A OE1 no hydrogen 2.238 N/A MET 161.A N VAL 158.A O no hydrogen 3.087 N/A GLU 164.A N GLU 164.A OE1 no hydrogen 2.895 N/A ALA 165.A N PRO 162.A O no hydrogen 3.275 N/A LYS 167.A N PRO 163.A O no hydrogen 2.872 N/A ASP 168.A N GLU 164.A O no hydrogen 3.253 N/A SER 171.A N SER 174.A OG no hydrogen 3.090 N/A LYS 173.A NZ PRO 235.A O no hydrogen 3.084 N/A LYS 173.A NZ ARG 238.A O no hydrogen 2.804 N/A SER 174.A N SER 171.A O no hydrogen 2.765 N/A SER 174.A OG GLU 164.A OE2 no hydrogen 3.105 N/A SER 174.A OG SER 171.A O no hydrogen 3.296 N/A ASP 175.A N PRO 172.A O no hydrogen 3.136 N/A TRP 177.A N LYS 173.A O no hydrogen 3.291 N/A SER 178.A OG TYR 160.A O no hydrogen 2.651 N/A SER 178.A OG SER 174.A O no hydrogen 3.308 N/A LEU 179.A N ASP 175.A O no hydrogen 2.873 N/A GLY 180.A N VAL 176.A O no hydrogen 2.785 N/A CYS 181.A N TRP 177.A O no hydrogen 2.920 N/A CYS 181.A N SER 178.A O no hydrogen 3.171 N/A CYS 181.A SG ASN 159.A O no hydrogen 3.712 N/A CYS 181.A SG TRP 177.A O no hydrogen 3.487 N/A ILE 182.A N SER 178.A O no hydrogen 3.131 N/A LEU 183.A N LEU 179.A O no hydrogen 2.893 N/A TYR 184.A N GLY 180.A O no hydrogen 2.920 N/A TYR 184.A OH GLU 214.A O no hydrogen 2.684 N/A TYR 185.A N CYS 181.A O no hydrogen 2.903 N/A MET 186.A N ILE 182.A O no hydrogen 2.975 N/A THR 187.A N TYR 184.A O no hydrogen 3.278 N/A THR 187.A OG1 LEU 183.A O no hydrogen 2.728 N/A TYR 188.A N TYR 184.A O no hydrogen 2.785 N/A TYR 188.A OH PRO 216.A O no hydrogen 2.734 N/A GLY 189.A N TYR 185.A O no hydrogen 2.796 N/A THR 191.A OG1 GLN 194.A OE1 no hydrogen 2.961 N/A GLN 194.A N THR 191.A O no hydrogen 3.114 N/A ILE 196.A N PHE 193.A O no hydrogen 3.038 N/A GLN 199.A NE2 ILE 197.A O no hydrogen 2.847 N/A ILE 200.A N ASN 198.A OD1 no hydrogen 3.187 N/A SER 201.A N ASN 198.A OD1 no hydrogen 3.340 N/A SER 201.A OG ASN 198.A OD1 no hydrogen 3.508 N/A LYS 202.A N ASN 198.A O no hydrogen 3.005 N/A LYS 202.A NZ ASN 159.A OD1 no hydrogen 2.814 N/A LYS 202.A NZ ILE 196.A O no hydrogen 2.966 N/A LEU 203.A N GLN 199.A O no hydrogen 3.377 N/A HIS 204.A N ILE 200.A O no hydrogen 3.160 N/A ALA 205.A N SER 201.A O no hydrogen 3.033 N/A ILE 206.A N LYS 202.A O no hydrogen 3.036 N/A ILE 207.A N LEU 203.A O no hydrogen 3.300 N/A ASP 208.A N HIS 204.A O no hydrogen 2.930 N/A ASN 210.A N ASP 208.A OD1 no hydrogen 3.324 N/A HIS 211.A N ASP 208.A O no hydrogen 3.237 N/A LEU 223.A N GLU 220.A O no hydrogen 3.147 N/A GLN 224.A N GLU 220.A O no hydrogen 3.290 N/A ASP 225.A N LYS 221.A O no hydrogen 3.036 N/A VAL 226.A N ASP 222.A O no hydrogen 3.089 N/A LEU 227.A N LEU 223.A O no hydrogen 3.090 N/A LYS 228.A N GLN 224.A O no hydrogen 3.015 N/A CYS 229.A N ASP 225.A O no hydrogen 2.957 N/A CYS 229.A SG ASP 225.A O no hydrogen 3.404 N/A CYS 229.A SG ASP 225.A OD2 no hydrogen 3.709 N/A CYS 230.A N VAL 226.A O no hydrogen 2.986 N/A CYS 230.A SG VAL 226.A O no hydrogen 3.240 N/A LEU 231.A N LEU 227.A O no hydrogen 3.034 N/A ARG 233.A NE ILE 206.A O no hydrogen 2.945 N/A ARG 233.A NH1 HIS 211.A O no hydrogen 3.094 N/A ARG 233.A NH2 ALA 205.A O no hydrogen 3.260 N/A ARG 233.A NH2 HIS 211.A O no hydrogen 2.636 N/A LYS 236.A N ASP 234.A OD1 no hydrogen 3.296 N/A ARG 238.A N ASP 234.A O no hydrogen 2.924 N/A ARG 238.A NE LYS 232.A O no hydrogen 2.780 N/A ARG 238.A NH1 GLU 164.A OE1 no hydrogen 3.185 N/A ARG 238.A NH1 GLU 164.A OE2 no hydrogen 2.789 N/A ARG 238.A NH1 LYS 173.A O no hydrogen 3.016 N/A ARG 238.A NH2 GLU 164.A OE1 no hydrogen 3.043 N/A ARG 238.A NH2 LYS 232.A O no hydrogen 2.926 N/A ILE 239.A N CYS 229.A O no hydrogen 3.362 N/A GLU 243.A N SER 240.A OG no hydrogen 3.253 N/A LEU 244.A N SER 240.A O no hydrogen 2.799 N/A LEU 245.A N ILE 241.A O no hydrogen 2.955 N/A ALA 246.A N GLU 243.A O no hydrogen 2.814 N/A HIS 247.A N LEU 244.A O no hydrogen 3.308 N/A HIS 247.A NE2 ASP 225.A OD2 no hydrogen 2.777 N/A TYR 249.A N HIS 247.A ND1 no hydrogen 2.905 N/A VAL 250.A N HIS 247.A O no hydrogen 3.036 N/A GLN 251.A N HIS 247.A O no hydrogen 3.125 N/A GLN 251.A NE2 LEU 245.A O no hydrogen 2.835 N/A ILE 252.A N PRO 248.A O no hydrogen 2.702 N/A GLN 253.A N GLN 253.A OE1 no hydrogen 2.793 N/A