Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4c89_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 8.A N ASN 26.A OD1 no hydrogen 2.864 N/A ILE 10.A N VAL 21.A O no hydrogen 2.835 N/A THR 12.A N LYS 19.A O no hydrogen 2.895 N/A VAL 14.A N VAL 17.A O no hydrogen 2.903 N/A ASN 15.A ND2 GLN 292.A OE1 no hydrogen 2.790 N/A VAL 17.A N VAL 14.A O no hydrogen 3.154 N/A VAL 18.A N THR 301.A O no hydrogen 3.033 N/A LYS 19.A N THR 12.A O no hydrogen 2.749 N/A ILE 20.A N PHE 303.A O no hydrogen 2.850 N/A VAL 21.A N ILE 10.A O no hydrogen 2.806 N/A LYS 22.A N GLN 305.A O no hydrogen 2.910 N/A LYS 22.A NZ ASP 325.A OD2 no hydrogen 2.814 N/A ASN 26.A ND2 THR 6.A O no hydrogen 2.773 N/A ASP 27.A N ASN 25.A OD1 no hydrogen 2.913 N/A ILE 28.A N ASN 25.A OD1 no hydrogen 3.029 N/A GLU 31.A N GLU 279.A OE2 no hydrogen 2.731 N/A PHE 33.A N GLN 228.A OE1 no hydrogen 2.867 N/A ASP 34.A N GLY 308.A O no hydrogen 2.904 N/A HIS 36.A N ASP 34.A OD1 no hydrogen 2.823 N/A HIS 36.A ND1 ASP 34.A OD1 no hydrogen 2.839 N/A LEU 38.A N ASP 34.A O no hydrogen 2.950 N/A GLN 39.A N PRO 35.A O no hydrogen 3.300 N/A GLN 39.A NE2 HIS 36.A O no hydrogen 3.565 N/A THR 40.A N VAL 37.A O no hydrogen 2.907 N/A THR 40.A OG1 VAL 37.A O no hydrogen 2.707 N/A LEU 41.A N LEU 38.A O no hydrogen 3.049 N/A PHE 44.A N LEU 41.A O no hydrogen 2.962 N/A LYS 45.A N THR 42.A O no hydrogen 3.242 N/A GLN 46.A N ALA 43.A O no hydrogen 3.334 N/A LEU 50.A N GLN 241.A OE1 no hydrogen 2.927 N/A ASP 53.A N GLU 51.A O no hydrogen 2.824 N/A ALA 56.A N ASP 53.A OD2 no hydrogen 3.077 N/A LEU 57.A N ASP 53.A O no hydrogen 2.943 N/A ARG 58.A N LEU 54.A O no hydrogen 2.863 N/A ARG 58.A NE TYR 113.A O no hydrogen 2.680 N/A ARG 58.A NH1 GLU 145.A OE2 no hydrogen 2.909 N/A ARG 58.A NH2 TYR 113.A O no hydrogen 2.987 N/A ARG 58.A NH2 ALA 143.A O no hydrogen 2.871 N/A ARG 58.A NH2 GLU 145.A OE1 no hydrogen 2.704 N/A ARG 58.A NH2 GLU 145.A OE2 no hydrogen 3.395 N/A SER 59.A N ALA 55.A O no hydrogen 2.919 N/A SER 59.A OG ALA 56.A O no hydrogen 2.764 N/A GLY 60.A N LEU 57.A O no hydrogen 3.077 N/A SER 61.A N ARG 58.A O no hydrogen 3.036 N/A SER 61.A OG ARG 58.A O no hydrogen 2.710 N/A THR 63.A N ASN 119.A OD1 no hydrogen 2.984 N/A ALA 67.A N ASP 318.A OD2 no hydrogen 3.077 N/A VAL 70.A N ASP 68.A OD1 no hydrogen 2.862 N/A GLY 71.A N ASP 68.A OD1 no hydrogen 3.075 N/A ALA 73.A N VAL 70.A O no hydrogen 3.179 N/A THR 75.A N THR 94.A O no hydrogen 2.761 N/A GLN 77.A N TRP 92.A O no hydrogen 2.999 N/A ARG 79.A N VAL 90.A O no hydrogen 2.848 N/A ILE 81.A N VAL 88.A O no hydrogen 2.922 N/A THR 82.A OG1 THR 87.A OG1 no hydrogen 2.999 N/A ALA 83.A N ARG 86.A O no hydrogen 3.128 N/A ARG 86.A N ALA 83.A O no hydrogen 2.890 N/A ARG 86.A NE ASP 154.A OD1 no hydrogen 2.711 N/A ARG 86.A NH2 ASP 154.A OD1 no hydrogen 2.956 N/A THR 87.A OG1 THR 82.A OG1 no hydrogen 2.999 N/A VAL 88.A N ILE 81.A O no hydrogen 2.814 N/A SER 89.A OG ASN 80.A OD1 no hydrogen 2.922 N/A VAL 90.A N ARG 79.A O no hydrogen 2.788 N/A GLU 91.A N ASN 137.A O no hydrogen 2.929 N/A TRP 92.A N GLN 77.A O no hydrogen 2.757 N/A TRP 92.A NE1 GLU 134.A OE1 no hydrogen 3.313 N/A LEU 93.A N ILE 135.A O no hydrogen 2.891 N/A THR 94.A N THR 75.A O no hydrogen 2.912 N/A ILE 99.A N HIS 132.A O no hydrogen 2.866 N/A HIS 101.A ND1 ASP 166.A OD2 no hydrogen 3.338 N/A THR 102.A N ASN 100.A O no hydrogen 2.646 N/A LEU 104.A N GLU 134.A O no hydrogen 3.204 N/A VAL 105.A N THR 171.A O no hydrogen 2.848 N/A TYR 106.A N LEU 136.A O no hydrogen 2.811 N/A TYR 106.A OH ASP 175.A OD2 no hydrogen 2.729 N/A PHE 107.A N ALA 173.A O no hydrogen 2.983 N/A HIS 108.A ND1 GLY 109.A O no hydrogen 2.716 N/A GLY 109.A N ASP 175.A OD2 no hydrogen 3.198 N/A GLY 114.A N GLY 110.A O no hydrogen 2.854 N/A GLY 115.A N SER 61.A OG no hydrogen 3.019 N/A ASN 119.A N VAL 116.A O no hydrogen 3.054 N/A ASN 119.A ND2 SER 61.A O no hydrogen 2.742 N/A ASN 120.A N PRO 117.A O no hydrogen 3.197 N/A ASN 120.A ND2 ASN 137.A OD1 no hydrogen 2.957 N/A THR 121.A N GLY 118.A O no hydrogen 3.533 N/A THR 121.A OG1 GLU 91.A OE1 no hydrogen 2.484 N/A THR 121.A OG1 GLU 91.A OE2 no hydrogen 3.434 N/A LEU 124.A N ASN 120.A O no hydrogen 3.241 N/A LYS 125.A N THR 121.A O no hydrogen 2.843 N/A LYS 125.A NZ ASP 68.A OD2 no hydrogen 2.552 N/A LYS 125.A NZ GLY 71.A O no hydrogen 2.704 N/A LEU 126.A N VAL 122.A O no hydrogen 3.091 N/A VAL 127.A N LEU 123.A O no hydrogen 3.159 N/A ALA 128.A N LEU 124.A O no hydrogen 2.836 N/A ALA 129.A N LYS 125.A O no hydrogen 2.868 N/A LYS 130.A N LEU 126.A O no hydrogen 3.120 N/A SER 131.A N VAL 127.A O no hydrogen 3.002 N/A SER 131.A OG VAL 127.A O no hydrogen 2.708 N/A HIS 132.A N ALA 128.A O no hydrogen 2.663 N/A HIS 132.A ND1 GLN 96.A O no hydrogen 2.803 N/A CYS 133.A N.A SER 131.A OG no hydrogen 3.276 N/A CYS 133.A N.B SER 131.A OG no hydrogen 3.292 N/A CYS 133.A SG.A SER 131.A O no hydrogen 3.861 N/A CYS 133.A SG.B THR 102.A O no hydrogen 3.289 N/A CYS 133.A SG.B GLU 134.A O no hydrogen 3.399 N/A ILE 135.A N LEU 93.A O no hydrogen 3.048 N/A LEU 136.A N LEU 104.A O no hydrogen 2.847 N/A ASN 137.A N GLU 91.A O no hydrogen 2.800 N/A ASN 137.A ND2 GLU 91.A OE1 no hydrogen 2.993 N/A ASN 137.A ND2 PRO 117.A O no hydrogen 2.745 N/A VAL 138.A N TYR 106.A O no hydrogen 2.969 N/A ASP 139.A N SER 89.A O no hydrogen 2.928 N/A TYR 140.A OH HIS 108.A O no hydrogen 2.540 N/A SER 141.A N ASP 154.A OD2 no hydrogen 2.793 N/A SER 141.A OG ASP 154.A OD2 no hydrogen 2.665 N/A ALA 143.A N PHE 112.A O no hydrogen 2.910 N/A GLU 145.A N GLU 145.A OE1 no hydrogen 2.715 N/A ALA 146.A N LEU 142.A O no hydrogen 2.926 N/A ALA 148.A N TYR 249.A O no hydrogen 2.841 N/A ALA 150.A N PRO 147.A O no hydrogen 2.936 N/A LEU 153.A N PRO 149.A O no hydrogen 2.868 N/A ASP 154.A N ALA 150.A O no hydrogen 2.923 N/A GLY 155.A N GLY 151.A O no hydrogen 3.123 N/A LEU 156.A N ILE 152.A O no hydrogen 3.099 N/A ALA 157.A N LEU 153.A O no hydrogen 2.927 N/A ILE 158.A N ASP 154.A O no hydrogen 2.971 N/A PHE 159.A N GLY 155.A O no hydrogen 2.936 N/A GLN 160.A N LEU 156.A O no hydrogen 2.948 N/A TYR 161.A N ALA 157.A O no hydrogen 2.964 N/A LEU 162.A N ILE 158.A O no hydrogen 3.013 N/A GLU 163.A N PHE 159.A O no hydrogen 3.005 N/A GLN 164.A N GLN 160.A O no hydrogen 2.953 N/A ARG 165.A N TYR 161.A O no hydrogen 3.005 N/A ARG 165.A NH2 GLU 134.A OE2 no hydrogen 2.484 N/A ASP 166.A N LEU 162.A O no hydrogen 3.203 N/A GLU 168.A N ASP 166.A OD1 no hydrogen 3.024 N/A THR 169.A N ASP 166.A O no hydrogen 3.308 N/A THR 169.A OG1 HIS 101.A O no hydrogen 3.142 N/A THR 171.A N VAL 103.A O no hydrogen 2.851 N/A VAL 172.A N GLN 198.A O no hydrogen 3.023 N/A ALA 173.A N VAL 105.A O no hydrogen 2.771 N/A GLY 174.A N LEU 200.A O no hydrogen 3.422 N/A ASP 175.A N PHE 107.A O no hydrogen 3.323 N/A SER 176.A N LEU 202.A O no hydrogen 2.934 N/A SER 176.A OG HIS 311.A NE2 no hydrogen 2.784 N/A ALA 179.A N ASP 175.A O no hydrogen 3.303 N/A ASN 180.A N SER 176.A O no hydrogen 3.312 N/A ASN 180.A ND2 VAL 205.A O no hydrogen 2.717 N/A ASN 180.A ND2 ILE 261.A O no hydrogen 2.975 N/A VAL 181.A N ALA 177.A O no hydrogen 3.112 N/A ILE 182.A N GLY 178.A O no hydrogen 3.163 N/A ALA 184.A N VAL 181.A O no hydrogen 3.004 N/A THR 185.A N ILE 182.A O no hydrogen 2.883 N/A THR 185.A OG1 ILE 182.A O no hydrogen 2.748 N/A LEU 187.A N ALA 183.A O no hydrogen 3.091 N/A ASN 188.A N ALA 184.A O no hydrogen 2.876 N/A ASN 188.A ND2 GLU 163.A OE2 no hydrogen 3.457 N/A GLN 189.A N THR 185.A O no hydrogen 3.017 N/A GLN 190.A N ASN 186.A O no hydrogen 3.013 N/A GLN 190.A NE2 ASN 186.A OD1 no hydrogen 2.935 N/A LEU 191.A N LEU 187.A O no hydrogen 3.227 N/A LEU 191.A N ASN 188.A O no hydrogen 3.334 N/A GLY 192.A N GLN 189.A O no hydrogen 2.882 N/A SER 193.A N ASN 188.A O no hydrogen 3.225 N/A SER 193.A OG GLU 163.A OE1 no hydrogen 2.585 N/A SER 193.A OG GLU 163.A OE2 no hydrogen 2.792 N/A SER 193.A OG ASN 188.A OD1 no hydrogen 2.891 N/A ARG 195.A NE ASN 194.A OD1.A no hydrogen 3.480 N/A ASN 197.A N ILE 170.A O no hydrogen 2.900 N/A GLN 198.A NE2 THR 171.A OG1 no hydrogen 3.015 N/A GLN 198.A NE2 ALA 332.A O no hydrogen 2.948 N/A GLN 199.A N PRO 273.A O no hydrogen 2.945 N/A GLN 199.A NE2 THR 274.A OG1 no hydrogen 2.837 N/A GLN 199.A NE2 TYR 290.A OH no hydrogen 3.369 N/A LEU 200.A N VAL 172.A O no hydrogen 2.851 N/A LEU 201.A N THR 275.A O no hydrogen 2.806 N/A LEU 202.A N GLY 174.A O no hydrogen 2.899 N/A VAL 205.A N SER 176.A O no hydrogen 3.250 N/A THR 206.A N GLN 286.A OE1 no hydrogen 2.960 N/A THR 206.A OG1 GLN 286.A O no hydrogen 2.865 N/A ALA 207.A N GLN 286.A OE1 no hydrogen 2.950 N/A ASN 209.A N ASP 243.A OD1 no hydrogen 2.915 N/A HIS 212.A NE2 ASP 243.A OD2 no hydrogen 2.770 N/A ALA 213.A N ASP 211.A OD1 no hydrogen 3.015 N/A GLY 214.A N ASP 211.A O no hydrogen 2.949 N/A TRP 217.A N GLY 214.A O no hydrogen 3.026 N/A ALA 220.A N ASP 218.A OD1 no hydrogen 3.109 N/A ALA 221.A N ASP 218.A O no hydrogen 3.065 N/A PHE 222.A N LEU 219.A O no hydrogen 3.087 N/A ILE 225.A N GLU 31.A O no hydrogen 2.887 N/A GLN 228.A N ILE 225.A O no hydrogen 3.056 N/A ARG 229.A N ASP 226.A O no hydrogen 3.154 N/A ARG 229.A NH1 ASP 226.A OD2 no hydrogen 3.190 N/A ARG 229.A NH2 ILE 224.A O no hydrogen 2.941 N/A LEU 232.A N GLN 228.A O no hydrogen 3.010 N/A THR 233.A N ARG 229.A O no hydrogen 3.003 N/A THR 233.A OG1 ARG 229.A O no hydrogen 2.682 N/A ASN 234.A N ALA 230.A O no hydrogen 2.941 N/A ASN 234.A ND2 PHE 44.A O no hydrogen 2.876 N/A TYR 235.A N ILE 231.A O no hydrogen 2.909 N/A HIS 236.A N LEU 232.A O no hydrogen 2.894 N/A ASP 237.A N THR 233.A O no hydrogen 3.007 N/A LEU 238.A N ASN 234.A O no hydrogen 3.072 N/A PHE 239.A N TYR 235.A O no hydrogen 3.201 N/A ARG 240.A N HIS 236.A O no hydrogen 2.968 N/A ARG 240.A NH2 ASP 237.A OD1 no hydrogen 2.864 N/A GLN 241.A N ASP 237.A O no hydrogen 3.012 N/A GLN 241.A NE2 ALA 48.A O no hydrogen 2.887 N/A GLN 241.A NE2 ASP 237.A O no hydrogen 3.459 N/A GLN 241.A NE2 ASP 237.A OD2 no hydrogen 2.925 N/A LEU 242.A N LEU 238.A O no hydrogen 2.847 N/A ASP 243.A N PHE 239.A O no hydrogen 2.775 N/A SER 244.A N ARG 240.A O no hydrogen 3.480 N/A SER 244.A OG ASN 209.A OD1 no hydrogen 3.526 N/A ILE 245.A N GLN 241.A O no hydrogen 3.208 N/A THR 246.A OG1 ASP 243.A O no hydrogen 2.784 N/A ASP 247.A N SER 244.A O no hydrogen 3.184 N/A TYR 248.A N ILE 245.A O no hydrogen 3.252 N/A VAL 250.A N THR 246.A O no hydrogen 2.934 N/A PHE 254.A N PRO 251.A O no hydrogen 3.112 N/A HIS 257.A N.A ASP 255.A OD2 no hydrogen 2.811 N/A HIS 257.A N.B ASP 255.A OD2 no hydrogen 2.821 N/A SER 258.A N ASP 255.A O no hydrogen 3.214 N/A SER 258.A OG ASP 255.A O no hydrogen 2.821 N/A ILE 261.A N SER 258.A O no hydrogen 3.102 N/A SER 262.A N SER 258.A O no hydrogen 2.698 N/A SER 262.A OG SER 256.A O no hydrogen 2.622 N/A LEU 264.A N THR 206.A O no hydrogen 2.968 N/A HIS 265.A N SER 262.A O no hydrogen 2.712 N/A GLN 266.A N PRO 263.A O no hydrogen 3.147 N/A GLN 266.A NE2 ASN 268.A O no hydrogen 3.371 N/A ASN 268.A ND2 THR 270.A OG1 no hydrogen 2.739 N/A THR 270.A OG1 ASN 268.A OD1 no hydrogen 2.891 N/A THR 271.A OG1 PHE 269.A O no hydrogen 3.269 N/A THR 274.A N ALA 300.A O no hydrogen 2.976 N/A THR 274.A OG1 PRO 272.A O no hydrogen 2.856 N/A THR 275.A N GLN 199.A O no hydrogen 2.935 N/A ILE 276.A N THR 302.A O no hydrogen 2.816 N/A GLU 279.A N TYR 306.A O no hydrogen 2.831 N/A PHE 280.A N LEU 309.A O no hydrogen 2.893 N/A ASP 281.A N GLY 278.A O no hydrogen 3.195 N/A PHE 283.A N ASP 281.A OD1 no hydrogen 2.807 N/A ARG 284.A N ASP 281.A O no hydrogen 2.892 N/A ARG 284.A NE GLU 279.A O no hydrogen 2.755 N/A ARG 284.A NH2 ALA 221.A O no hydrogen 3.159 N/A ARG 284.A NH2 GLU 279.A O no hydrogen 3.001 N/A ALA 287.A N PHE 283.A O no hydrogen 3.048 N/A TRP 288.A N ARG 284.A O no hydrogen 2.892 N/A ALA 289.A N PRO 285.A O no hydrogen 2.939 N/A TYR 290.A N GLN 286.A O no hydrogen 3.070 N/A ALA 291.A N ALA 287.A O no hydrogen 3.020 N/A GLN 292.A N TRP 288.A O no hydrogen 2.978 N/A ARG 293.A N ALA 289.A O no hydrogen 3.222 N/A LEU 294.A N TYR 290.A O no hydrogen 3.129 N/A ALA 295.A N ALA 291.A O no hydrogen 3.063 N/A ALA 296.A N GLN 292.A O no hydrogen 3.057 N/A ALA 297.A N ARG 293.A O no hydrogen 3.167 N/A ALA 297.A N LEU 294.A O no hydrogen 2.808 N/A ASP 298.A N ALA 295.A O no hydrogen 2.869 N/A THR 299.A N LEU 294.A O no hydrogen 3.144 N/A THR 299.A OG1 PHE 269.A O no hydrogen 3.484 N/A THR 299.A OG1 THR 271.A O no hydrogen 3.185 N/A THR 301.A OG1 THR 299.A O no hydrogen 3.077 N/A THR 302.A N THR 274.A O no hydrogen 2.894 N/A PHE 303.A N VAL 18.A O no hydrogen 2.769 N/A ILE 304.A N ILE 276.A O no hydrogen 2.813 N/A GLN 305.A N ILE 20.A O no hydrogen 2.732 N/A GLN 305.A NE2 GLN 307.A OE1 no hydrogen 2.798 N/A TYR 306.A N VAL 277.A O no hydrogen 2.772 N/A TYR 306.A OH ASP 325.A OD2 no hydrogen 2.675 N/A GLN 307.A N LYS 22.A O no hydrogen 2.963 N/A GLN 307.A NE2 ALA 29.A O no hydrogen 2.931 N/A GLY 308.A N GLU 279.A OE1 no hydrogen 2.970 N/A LEU 309.A N TYR 306.A O no hydrogen 3.445 N/A HIS 311.A N TYR 235.A OH no hydrogen 2.887 N/A HIS 311.A ND1 ASP 281.A OD1 no hydrogen 3.114 N/A HIS 311.A ND1 ASP 281.A OD2 no hydrogen 2.779 N/A HIS 311.A NE2 SER 176.A OG no hydrogen 2.784 N/A ALA 314.A N TYR 203.A OH no hydrogen 3.149 N/A LEU 316.A N PHE 313.A O no hydrogen 2.921 N/A VAL 317.A N PRO 315.A O no hydrogen 2.834 N/A GLN 319.A N LEU 316.A O no hydrogen 3.013 N/A TYR 320.A N LEU 316.A O no hydrogen 3.172 N/A TRP 321.A NE1 PHE 24.A O no hydrogen 3.267 N/A GLN 322.A N GLN 322.A OE1 no hydrogen 2.845 N/A GLN 322.A NE2 ASP 34.A OD2 no hydrogen 3.092 N/A SER 323.A N TYR 320.A O no hydrogen 3.165 N/A SER 323.A OG PHE 313.A O no hydrogen 2.806 N/A SER 323.A OG LEU 316.A O no hydrogen 3.302 N/A GLN 324.A N TYR 320.A O no hydrogen 3.479 N/A ASP 325.A N TRP 321.A O no hydrogen 2.869 N/A VAL 326.A N GLN 322.A O no hydrogen 2.934 N/A ALA 327.A N SER 323.A O no hydrogen 3.180 N/A GLN 328.A N GLN 324.A O no hydrogen 3.104 N/A GLN 328.A NE2 ASP 325.A OD1 no hydrogen 3.313 N/A VAL 329.A N ASP 325.A O no hydrogen 2.824 N/A ALA 331.A N GLN 328.A O no hydrogen 2.992 N/A ALA 332.A N VAL 329.A O no hydrogen 3.124 N/A LEU 333.A N ALA 330.A O no hydrogen 3.155 N/A