Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4cbi_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 5.A N LEU 1.A O no hydrogen 2.845 N/A LYS 6.A N THR 2.A O no hydrogen 3.038 N/A LYS 7.A N GLU 3.A O no hydrogen 2.985 N/A LYS 7.A NZ GLU 3.A OE1 no hydrogen 3.313 N/A ILE 8.A N MET 4.A O no hydrogen 2.810 N/A THR 9.A N VAL 5.A O no hydrogen 2.808 N/A THR 9.A OG1 VAL 5.A O no hydrogen 2.739 N/A THR 9.A OG1 LYS 6.A O no hydrogen 3.401 N/A THR 10.A N LYS 6.A O no hydrogen 3.262 N/A THR 10.A OG1 LYS 6.A O no hydrogen 2.793 N/A THR 10.A OG1 LYS 7.A O no hydrogen 3.012 N/A MET 11.A N ILE 8.A O no hydrogen 3.054 N/A ASN 12.A N GLU 15.A OE2 no hydrogen 2.704 N/A ARG 13.A NH1 ASN 132.A O no hydrogen 2.715 N/A GLY 14.A N LEU 133.A O no hydrogen 2.716 N/A GLU 15.A N ASN 12.A O no hydrogen 3.177 N/A ARG 17.A N VAL 135.A O no hydrogen 2.907 N/A ARG 17.A NH1 GLU 15.A OE1 no hydrogen 2.815 N/A ARG 17.A NH2 GLU 15.A OE1 no hydrogen 3.043 N/A GLN 18.A NE2 SER 270.A O no hydrogen 3.622 N/A ILE 19.A N ALA 137.A O no hydrogen 2.649 N/A LEU 21.A N THR 139.A O no hydrogen 2.965 N/A ARG 27.A NE GLU 24.A OE1 no hydrogen 2.786 N/A ARG 27.A NH2 GLU 24.A OE1 no hydrogen 2.829 N/A SER 28.A N GLU 24.A O no hydrogen 2.848 N/A SER 28.A OG GLU 24.A O no hydrogen 2.718 N/A VAL 29.A N LEU 25.A O no hydrogen 2.890 N/A ILE 30.A N PRO 26.A O no hydrogen 2.944 N/A GLU 31.A N ARG 27.A O no hydrogen 2.991 N/A GLU 32.A N SER 28.A O no hydrogen 3.035 N/A GLU 32.A N VAL 29.A O no hydrogen 3.185 N/A ILE 33.A N VAL 29.A O no hydrogen 2.997 N/A GLY 34.A N ILE 30.A O no hydrogen 2.934 N/A ARG 35.A NE SER 62.A O no hydrogen 3.348 N/A LYS 37.A N GLY 34.A O no hydrogen 3.169 N/A LYS 37.A NZ ILE 33.A O no hydrogen 2.971 N/A VAL 39.A N GLY 80.A O no hydrogen 3.456 N/A LEU 40.A N PHE 106.A O no hydrogen 2.966 N/A VAL 41.A N THR 82.A O no hydrogen 2.811 N/A LEU 42.A N PHE 108.A O no hydrogen 2.805 N/A ILE 43.A N ALA 84.A O no hydrogen 2.864 N/A ALA 49.A N LEU 45.A O no hydrogen 2.989 N/A GLU 50.A N ARG 46.A O no hydrogen 2.928 N/A SER 51.A N ALA 47.A O no hydrogen 2.905 N/A VAL 52.A N ALA 48.A O no hydrogen 3.041 N/A TYR 53.A N ALA 49.A O no hydrogen 2.962 N/A GLN 54.A N GLU 50.A O no hydrogen 2.953 N/A TYR 55.A N SER 51.A O no hydrogen 3.099 N/A MET 56.A N VAL 52.A O no hydrogen 2.824 N/A ARG 57.A N TYR 53.A O no hydrogen 2.918 N/A ARG 57.A NE GLN 54.A OE1 no hydrogen 2.786 N/A ARG 57.A NH2 GLN 54.A OE1 no hydrogen 2.903 N/A GLN 58.A N GLN 54.A O no hydrogen 3.144 N/A LYS 59.A N TYR 55.A O no hydrogen 3.068 N/A HIS 60.A N MET 56.A O no hydrogen 2.750 N/A SER 62.A OG PRO 61.A O no hydrogen 2.515 N/A ILE 63.A N HIS 60.A O no hydrogen 3.206 N/A ASN 66.A N ILE 81.A O no hydrogen 2.806 N/A ASN 66.A ND2 THR 79.A O no hydrogen 2.934 N/A ASN 66.A ND2 ILE 81.A O no hydrogen 3.546 N/A ASN 66.A ND2 THR 82.A OG1 no hydrogen 3.363 N/A ARG 68.A N TYR 83.A O no hydrogen 2.860 N/A ARG 68.A NE ASP 76.A OD2 no hydrogen 2.793 N/A ARG 68.A NH1 LEU 67.A O no hydrogen 3.045 N/A ARG 68.A NH2 ASP 76.A OD1 no hydrogen 2.917 N/A LYS 73.A N TYR 88.A OH no hydrogen 2.911 N/A LYS 73.A NZ ASP 76.A OD1 no hydrogen 3.491 N/A ASP 76.A N LYS 73.A O no hydrogen 3.277 N/A ALA 78.A N ASP 76.A OD1 no hydrogen 3.110 N/A GLY 80.A N LYS 37.A O no hydrogen 3.299 N/A ILE 81.A N ALA 64.A O no hydrogen 2.922 N/A THR 82.A N VAL 39.A O no hydrogen 2.737 N/A TYR 83.A N ASN 66.A O no hydrogen 2.831 N/A ALA 84.A N VAL 41.A O no hydrogen 2.953 N/A SER 85.A N ARG 68.A O no hydrogen 3.284 N/A TYR 86.A OH ASP 110.A O no hydrogen 2.975 N/A TYR 88.A N SER 85.A O no hydrogen 2.977 N/A TYR 88.A N SER 85.A OG no hydrogen 3.262 N/A PHE 89.A N TYR 86.A O no hydrogen 3.218 N/A CYS 90.A N GLY 87.A O no hydrogen 3.214 N/A CYS 90.A SG TYR 86.A O no hydrogen 3.537 N/A CYS 90.A SG GLU 118.A O no hydrogen 3.852 N/A GLN 91.A NE2 GLY 70.A O no hydrogen 2.790 N/A GLN 94.A N ASP 254.A OD2 no hydrogen 2.693 N/A GLN 94.A NE2 LYS 125.A O no hydrogen 2.956 N/A LEU 97.A N SER 93.A O no hydrogen 2.698 N/A ARG 98.A N GLN 94.A O no hydrogen 2.751 N/A ALA 99.A N PRO 95.A O no hydrogen 2.964 N/A ALA 100.A N LYS 96.A O no hydrogen 2.842 N/A MET 101.A N LEU 97.A O no hydrogen 2.822 N/A VAL 102.A N ARG 98.A O no hydrogen 2.960 N/A GLU 103.A N ALA 100.A O no hydrogen 3.356 N/A TYR 104.A N MET 101.A O no hydrogen 3.268 N/A SER 105.A N ARG 38.A O no hydrogen 2.773 N/A ILE 107.A N ARG 134.A O no hydrogen 2.935 N/A PHE 108.A N LEU 40.A O no hydrogen 2.817 N/A LEU 109.A N VAL 136.A O no hydrogen 2.871 N/A ASP 110.A N LEU 42.A O no hydrogen 2.982 N/A HIS 113.A ND1 THR 139.A OG1 no hydrogen 3.107 N/A CYS 114.A N GLU 111.A O no hydrogen 3.186 N/A CYS 114.A SG GLU 111.A OE1 no hydrogen 3.832 N/A ALA 115.A N TYR 112.A O no hydrogen 3.367 N/A THR 116.A N GLN 119.A OE1 no hydrogen 3.276 N/A THR 116.A OG1 GLU 118.A OE1 no hydrogen 3.515 N/A GLN 119.A N THR 116.A OG1 no hydrogen 3.297 N/A GLN 119.A NE2 TYR 86.A OH no hydrogen 3.294 N/A GLN 119.A NE2 GLU 111.A O no hydrogen 2.789 N/A LEU 120.A N THR 116.A O no hydrogen 2.853 N/A ALA 121.A N PRO 117.A O no hydrogen 3.084 N/A ILE 122.A N GLU 118.A O no hydrogen 3.022 N/A MET 123.A N GLN 119.A O no hydrogen 2.944 N/A GLY 124.A N LEU 120.A O no hydrogen 3.296 N/A LYS 125.A N ALA 121.A O no hydrogen 2.909 N/A LYS 125.A NZ TYR 250.A O no hydrogen 2.950 N/A ILE 126.A N ILE 122.A O no hydrogen 2.812 N/A HIS 127.A N MET 123.A O no hydrogen 3.079 N/A ARG 128.A N LYS 125.A O no hydrogen 3.130 N/A PHE 129.A N ILE 126.A O no hydrogen 2.889 N/A SER 130.A N HIS 127.A O no hydrogen 3.087 N/A SER 130.A OG HIS 127.A O no hydrogen 2.865 N/A ASN 132.A N PHE 129.A O no hydrogen 2.977 N/A LEU 133.A N SER 130.A O no hydrogen 3.081 N/A ARG 134.A NE MET 11.A O no hydrogen 2.894 N/A ARG 134.A NH1 SER 105.A O no hydrogen 2.808 N/A VAL 135.A N GLU 15.A O no hydrogen 3.244 N/A VAL 136.A N ILE 107.A O no hydrogen 2.883 N/A ALA 137.A N ARG 17.A O no hydrogen 2.844 N/A MET 138.A N LEU 109.A O no hydrogen 2.902 N/A THR 139.A N ILE 19.A O no hydrogen 3.010 N/A THR 139.A OG1 HIS 113.A ND1 no hydrogen 3.107 N/A VAL 146.A N GLY 151.A O no hydrogen 3.036 N/A LEU 152.A N ILE 149.A O no hydrogen 3.058 N/A LYS 153.A N PRO 144.A O no hydrogen 2.814 N/A GLU 158.A N PRO 155.A O no hydrogen 3.230 N/A MET 159.A N VAL 156.A O no hydrogen 3.065 N/A LYS 160.A N GLU 157.A O no hydrogen 3.279 N/A ASN 161.A N GLU 158.A O no hydrogen 3.146 N/A MET 163.A N TYR 178.A O no hydrogen 2.794 N/A VAL 165.A N VAL 180.A O no hydrogen 2.786 N/A VAL 167.A N ALA 182.A O no hydrogen 3.361 N/A MET 172.A N THR 169.A OG1 no hydrogen 3.364 N/A ALA 173.A N THR 169.A O no hydrogen 3.421 N/A GLU 175.A N ASN 171.A O no hydrogen 3.015 N/A ALA 176.A N MET 172.A O no hydrogen 3.108 N/A TYR 178.A N ASN 162.A OD1 no hydrogen 3.286 N/A VAL 180.A N MET 163.A O no hydrogen 3.040 N/A ALA 182.A N VAL 165.A O no hydrogen 2.868 N/A ILE 186.A N THR 183.A O no hydrogen 2.760 N/A SER 188.A OG ALA 185.A O no hydrogen 2.557 N/A THR 191.A N PHE 166.A O no hydrogen 3.174 N/A THR 191.A OG1 ALA 150.A O no hydrogen 3.440 N/A GLY 192.A N ASP 190.A OD1 no hydrogen 2.944 N/A LYS 194.A N MET 215.A O no hydrogen 3.016 N/A LYS 194.A NZ GLU 196.A OE2 no hydrogen 3.234 N/A LYS 194.A NZ GLU 221.A OE1 no hydrogen 3.565 N/A GLU 196.A N LYS 213.A O no hydrogen 3.052 N/A LYS 197.A NZ GLU 309.A OE2 no hydrogen 2.879 N/A ARG 198.A N GLY 211.A O no hydrogen 2.939 N/A ARG 200.A N VAL 209.A O no hydrogen 2.973 N/A ARG 200.A NH1 GLU 361.A OE2 no hydrogen 2.788 N/A SER 202.A N PHE 207.A O no hydrogen 3.079 N/A SER 202.A OG LYS 204.A O no hydrogen 2.791 N/A LYS 204.A N SER 202.A OG no hydrogen 3.226 N/A ILE 208.A N VAL 357.A O no hydrogen 3.070 N/A VAL 209.A N ARG 200.A O no hydrogen 3.146 N/A THR 210.A N ALA 359.A O no hydrogen 2.955 N/A THR 210.A OG1 GLU 309.A OE1 no hydrogen 2.882 N/A THR 210.A OG1 GLU 309.A OE2 no hydrogen 3.357 N/A GLY 211.A N ARG 198.A O no hydrogen 3.128 N/A LYS 213.A N GLU 196.A O no hydrogen 2.809 N/A MET 215.A N LYS 194.A O no hydrogen 2.884 N/A VAL 217.A N GLY 192.A O no hydrogen 3.035 N/A THR 218.A N GLU 221.A OE1 no hydrogen 3.049 N/A THR 218.A OG1 GLU 221.A OE1 no hydrogen 3.159 N/A ILE 219.A N VAL 235.A O no hydrogen 3.202 N/A GLU 221.A N THR 218.A OG1 no hydrogen 3.138 N/A GLN 222.A N THR 218.A O no hydrogen 2.838 N/A ALA 223.A N ILE 219.A O no hydrogen 2.936 N/A GLN 224.A N GLY 220.A O no hydrogen 3.053 N/A GLN 224.A NE2 GLY 220.A O no hydrogen 3.497 N/A ARG 225.A N GLU 221.A O no hydrogen 2.966 N/A ARG 225.A NH1 ASP 190.A OD1 no hydrogen 2.647 N/A ARG 225.A NH1 LEU 193.A O no hydrogen 3.012 N/A ARG 225.A NH2 LEU 193.A O no hydrogen 3.286 N/A ARG 226.A N GLN 222.A O no hydrogen 2.889 N/A GLY 227.A N ALA 223.A O no hydrogen 2.826 N/A VAL 229.A N ARG 226.A O no hydrogen 3.424 N/A SER 230.A OG THR 191.A O no hydrogen 3.400 N/A GLU 232.A N SER 230.A OG no hydrogen 3.282 N/A VAL 235.A N VAL 217.A O no hydrogen 3.160 N/A LYS 238.A NZ CYS 114.A O no hydrogen 3.011 N/A TYR 240.A OH GLU 273.A O no hydrogen 2.582 N/A HIS 241.A N ASP 239.A OD1 no hydrogen 3.185 N/A LEU 244.A N TYR 240.A O no hydrogen 2.818 N/A LEU 245.A N HIS 241.A O no hydrogen 3.025 N/A ALA 247.A N ASP 243.A O no hydrogen 2.764 N/A GLN 248.A N LEU 245.A O no hydrogen 3.072 N/A GLN 248.A NE2 THR 259.A OG1 no hydrogen 2.937 N/A ARG 249.A N GLN 246.A O no hydrogen 3.141 N/A TYR 250.A N ALA 247.A O no hydrogen 2.933 N/A TYR 250.A OH GLU 118.A OE2 no hydrogen 2.675 N/A GLY 251.A N GLN 248.A O no hydrogen 3.106 N/A GLY 255.A N ILE 252.A O no hydrogen 3.119 N/A ILE 256.A N GLY 251.A O no hydrogen 2.852 N/A ASN 257.A ND2 GLU 283.A O no hydrogen 3.269 N/A ASN 257.A ND2 ASN 287.A OD1 no hydrogen 2.825 N/A LYS 260.A N ASN 257.A OD1 no hydrogen 2.843 N/A SER 261.A N ASN 257.A O no hydrogen 3.118 N/A SER 261.A OG ASN 257.A O no hydrogen 3.010 N/A PHE 262.A N ILE 258.A O no hydrogen 2.789 N/A ARG 263.A N THR 259.A O no hydrogen 2.969 N/A ARG 263.A NE GLU 283.A OE1 no hydrogen 2.948 N/A ARG 263.A NH2 GLU 283.A OE2 no hydrogen 2.965 N/A GLU 264.A N LYS 260.A O no hydrogen 2.833 N/A MET 265.A N SER 261.A O no hydrogen 2.844 N/A ASN 266.A N PHE 262.A O no hydrogen 2.815 N/A ASN 266.A ND2 TYR 272.A O no hydrogen 3.044 N/A ASN 266.A ND2 GLU 274.A OE2 no hydrogen 3.058 N/A TYR 267.A N ARG 263.A O no hydrogen 3.023 N/A ASP 268.A N GLU 264.A O no hydrogen 3.396 N/A TRP 269.A N MET 265.A O no hydrogen 2.743 N/A SER 270.A N ASN 266.A O no hydrogen 2.767 N/A LEU 271.A N ASN 266.A OD1 no hydrogen 2.998 N/A TYR 272.A N ASN 266.A OD1 no hydrogen 2.941 N/A TYR 272.A OH TYR 112.A O no hydrogen 2.649 N/A MET 278.A N ASP 275.A OD1 no hydrogen 3.410 N/A ILE 279.A N ASP 275.A O no hydrogen 2.893 N/A THR 280.A N SER 276.A O no hydrogen 2.970 N/A THR 280.A OG1 SER 276.A O no hydrogen 2.641 N/A GLN 281.A N LEU 277.A O no hydrogen 2.952 N/A GLN 281.A NE2 LEU 277.A O no hydrogen 3.673 N/A LEU 282.A N MET 278.A O no hydrogen 2.895 N/A GLU 283.A N ILE 279.A O no hydrogen 2.829 N/A ILE 284.A N THR 280.A O no hydrogen 3.078 N/A LEU 285.A N GLN 281.A O no hydrogen 3.062 N/A ASN 286.A N LEU 282.A O no hydrogen 2.803 N/A ASN 286.A ND2 THR 259.A OG1 no hydrogen 2.712 N/A ASN 287.A N GLU 283.A O no hydrogen 3.059 N/A LEU 288.A N ILE 284.A O no hydrogen 3.339 N/A LEU 289.A N LEU 285.A O no hydrogen 2.868 N/A ILE 290.A N ASN 286.A O no hydrogen 3.238 N/A SER 291.A N LEU 288.A O no hydrogen 2.931 N/A SER 291.A OG LEU 288.A O no hydrogen 2.705 N/A GLU 292.A N TYR 318.A OH no hydrogen 3.246 N/A LYS 299.A N PRO 295.A O no hydrogen 2.955 N/A LYS 299.A NZ LEU 294.A O no hydrogen 2.843 N/A ASN 300.A N MET 296.A O no hydrogen 2.970 N/A ILE 301.A N ALA 297.A O no hydrogen 3.156 N/A MET 302.A N VAL 298.A O no hydrogen 2.992 N/A ALA 303.A N LYS 299.A O no hydrogen 3.106 N/A ARG 304.A N ASN 300.A O no hydrogen 3.010 N/A ARG 304.A N ILE 301.A O no hydrogen 2.904 N/A THR 305.A N ILE 301.A O no hydrogen 2.696 N/A THR 305.A OG1 ILE 301.A O no hydrogen 2.591 N/A THR 305.A OG1 THR 342.A O no hydrogen 3.194 N/A ASP 306.A N ASP 306.A OD1 no hydrogen 2.795 N/A GLN 312.A N GLU 309.A O no hydrogen 2.903 N/A GLN 312.A NE2 TYR 358.A O no hydrogen 2.584 N/A GLN 312.A NE2 GLU 363.A OE1 no hydrogen 3.353 N/A LEU 313.A N PRO 310.A O no hydrogen 2.950 N/A TYR 315.A N ILE 311.A O no hydrogen 2.920 N/A TYR 315.A OH GLN 248.A OE1 no hydrogen 2.553 N/A ASN 316.A N GLN 312.A O no hydrogen 2.928 N/A ASN 316.A ND2 TYR 358.A O no hydrogen 3.010 N/A SER 317.A N LEU 313.A O no hydrogen 3.184 N/A SER 317.A OG ALA 314.A O no hydrogen 2.987 N/A TYR 318.A N TYR 315.A O no hydrogen 3.157 N/A TYR 318.A OH LEU 289.A O no hydrogen 2.562 N/A GLU 319.A N ASN 316.A O no hydrogen 2.856 N/A THR 320.A N ASN 316.A O no hydrogen 2.829 N/A THR 320.A OG1 VAL 322.A O no hydrogen 3.367 N/A VAL 322.A N THR 320.A OG1 no hydrogen 3.243 N/A VAL 324.A N TYR 356.A OH no hydrogen 3.106 N/A LEU 325.A N ARG 347.A O no hydrogen 2.654 N/A LYS 328.A N THR 337.A O no hydrogen 2.649 N/A LYS 328.A NZ ASP 339.A OD1 no hydrogen 3.401 N/A GLU 333.A N ARG 330.A O no hydrogen 3.166 N/A THR 335.A N LYS 328.A O no hydrogen 2.955 N/A THR 335.A OG1 LYS 328.A O no hydrogen 3.089 N/A THR 335.A OG1 THR 337.A OG1 no hydrogen 2.525 N/A THR 337.A N THR 335.A OG1 no hydrogen 2.925 N/A THR 337.A OG1 THR 335.A OG1 no hydrogen 2.525 N/A THR 342.A N ASP 306.A OD1 no hydrogen 2.641 N/A THR 342.A OG1 ARG 304.A O no hydrogen 3.559 N/A THR 342.A OG1 ASP 306.A OD1 no hydrogen 3.058 N/A ARG 347.A N PRO 323.A O no hydrogen 3.070 N/A LEU 349.A N LEU 325.A O no hydrogen 2.747 N/A ASP 352.A N LEU 349.A O no hydrogen 3.129 N/A TYR 356.A N PRO 354.A O no hydrogen 2.737 N/A VAL 357.A N ASN 316.A OD1 no hydrogen 2.738 N/A TYR 358.A N ASN 316.A OD1 no hydrogen 2.801 N/A TYR 358.A OH GLU 309.A OE1 no hydrogen 2.513 N/A ALA 359.A N ILE 208.A O no hydrogen 2.716 N/A THR 360.A N GLU 363.A OE1 no hydrogen 3.165 N/A GLU 361.A N THR 210.A O no hydrogen 2.739 N/A ASP 364.A N THR 360.A O no hydrogen 2.943 N/A LEU 365.A N GLU 361.A O no hydrogen 2.898 N/A ALA 366.A N ASP 362.A O no hydrogen 2.938 N/A VAL 367.A N GLU 363.A O no hydrogen 3.207 N/A GLU 368.A N ASP 364.A O no hydrogen 2.996 N/A LEU 369.A N LEU 365.A O no hydrogen 2.755 N/A LEU 370.A N ALA 366.A O no hydrogen 2.975 N/A GLY 371.A N GLU 368.A O no hydrogen 2.742 N/A LEU 372.A N VAL 367.A O no hydrogen 2.861 N/A TRP 374.A NE1 ASP 364.A OD1 no hydrogen 2.717 N/A GLY 378.A N GLU 319.A OE2 no hydrogen 2.852 N/A ASN 379.A ND2 TYR 318.A O no hydrogen 2.746 N/A THR 382.A N ASN 379.A OD1 no hydrogen 2.999 N/A THR 382.A OG1 GLU 319.A OE2 no hydrogen 3.401 N/A VAL 383.A N ASN 379.A O no hydrogen 2.734 N/A GLU 384.A N GLN 380.A O no hydrogen 2.771 N/A ALA 385.A N GLY 381.A O no hydrogen 3.036 N/A GLY 386.A N THR 382.A O no hydrogen 3.183 N/A ARG 387.A N VAL 383.A O no hydrogen 3.012 N/A ALA 388.A N GLU 384.A O no hydrogen 2.929 N/A LEU 389.A N ALA 385.A O no hydrogen 2.838 N/A LYS 390.A N GLY 386.A O no hydrogen 2.964 N/A GLN 391.A N ARG 387.A O no hydrogen 2.973 N/A VAL 392.A N ALA 388.A O no hydrogen 3.061 N/A VAL 393.A N LEU 389.A O no hydrogen 3.167 N/A VAL 393.A N LYS 390.A O no hydrogen 3.268 N/A