Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4cfv_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 4.A N GLY 1.A O no hydrogen 2.799 N/A VAL 5.A N VAL 2.A O no hydrogen 2.836 N/A TYR 8.A N VAL 5.A O no hydrogen 2.941 N/A HIS 9.A N VAL 5.A O no hydrogen 2.857 N/A ILE 12.A N TYR 8.A O no hydrogen 2.853 N/A HIS 13.A N HIS 9.A O no hydrogen 2.939 N/A THR 14.A N GLU 10.A O no hydrogen 2.988 N/A THR 14.A OG1 GLU 10.A O no hydrogen 3.230 N/A TYR 15.A N ASP 11.A O no hydrogen 2.971 N/A LEU 16.A N ILE 12.A O no hydrogen 2.877 N/A ARG 17.A N HIS 13.A O no hydrogen 2.998 N/A ARG 17.A NH1 THR 210.A O no hydrogen 2.883 N/A GLU 18.A N THR 14.A O no hydrogen 3.153 N/A MET 19.A N TYR 15.A O no hydrogen 2.941 N/A GLU 20.A N LEU 16.A O no hydrogen 2.827 N/A LYS 22.A NZ GLU 18.A OE2 no hydrogen 2.884 N/A CYS 23.A N MET 19.A O no hydrogen 2.952 N/A CYS 23.A SG MET 19.A O no hydrogen 3.325 N/A LYS 24.A NZ LEU 178.A O no hydrogen 3.079 N/A LYS 26.A N SER 74.A OG no hydrogen 3.011 N/A LYS 26.A NZ SER 74.A O no hydrogen 3.307 N/A TYR 29.A N LYS 26.A O no hydrogen 3.370 N/A TYR 29.A OH ASP 70.A OD1 no hydrogen 2.520 N/A LYS 31.A N GLY 28.A O no hydrogen 3.337 N/A LYS 32.A N TYR 29.A O no hydrogen 2.901 N/A GLN 33.A N MET 30.A O no hydrogen 3.080 N/A GLN 33.A NE2 LEU 73.A O no hydrogen 2.977 N/A GLN 33.A NE2 MET 76.A O no hydrogen 2.774 N/A MET 40.A N THR 37.A OG1 no hydrogen 3.218 N/A ARG 41.A N THR 37.A O no hydrogen 3.056 N/A ARG 41.A NE ASP 70.A OD1 no hydrogen 2.689 N/A ARG 41.A NH1 LEU 171.A O no hydrogen 2.750 N/A ARG 41.A NH2 ASP 70.A OD1 no hydrogen 3.534 N/A ARG 41.A NH2 ASP 70.A OD2 no hydrogen 2.771 N/A ARG 41.A NH2 LEU 171.A O no hydrogen 2.920 N/A ALA 42.A N ASN 38.A O no hydrogen 2.932 N/A ILE 43.A N SER 39.A O no hydrogen 2.980 N/A LEU 44.A N MET 40.A O no hydrogen 2.957 N/A VAL 45.A N ARG 41.A O no hydrogen 2.891 N/A ASP 46.A N ALA 42.A O no hydrogen 2.977 N/A TRP 47.A N ILE 43.A O no hydrogen 2.924 N/A LEU 48.A N LEU 44.A O no hydrogen 2.964 N/A VAL 49.A N VAL 45.A O no hydrogen 3.009 N/A GLU 50.A N ASP 46.A O no hydrogen 3.143 N/A VAL 51.A N TRP 47.A O no hydrogen 2.867 N/A GLY 52.A N LEU 48.A O no hydrogen 2.834 N/A GLU 53.A N VAL 49.A O no hydrogen 2.940 N/A GLU 54.A N GLU 50.A O no hydrogen 2.792 N/A TYR 55.A N VAL 51.A O no hydrogen 2.989 N/A LYS 56.A N GLU 53.A O no hydrogen 3.330 N/A LEU 57.A N GLY 52.A O no hydrogen 2.830 N/A GLN 58.A N GLU 99.A OE2 no hydrogen 2.772 N/A THR 61.A OG1 GLU 99.A OE2 no hydrogen 2.557 N/A HIS 63.A N ASN 59.A O no hydrogen 3.085 N/A HIS 63.A ND1 ASN 59.A O no hydrogen 3.119 N/A LEU 64.A N GLU 60.A O no hydrogen 2.900 N/A ALA 65.A N THR 61.A O no hydrogen 2.927 N/A VAL 66.A N LEU 62.A O no hydrogen 3.091 N/A ASN 67.A N HIS 63.A O no hydrogen 3.107 N/A ASN 67.A ND2 CYS 23.A O no hydrogen 3.191 N/A TYR 68.A N LEU 64.A O no hydrogen 2.880 N/A TYR 68.A OH LEU 136.A O no hydrogen 2.693 N/A ILE 69.A N ALA 65.A O no hydrogen 2.949 N/A ASP 70.A N VAL 66.A O no hydrogen 2.869 N/A ARG 71.A N ASN 67.A O no hydrogen 3.024 N/A ARG 71.A NH1 ASN 67.A OD1 no hydrogen 2.858 N/A ARG 71.A NH1 ASP 135.A O no hydrogen 2.898 N/A ARG 71.A NH2 ASP 135.A O no hydrogen 2.805 N/A PHE 72.A N TYR 68.A O no hydrogen 2.914 N/A LEU 73.A N ILE 69.A O no hydrogen 2.842 N/A SER 74.A N ASP 70.A O no hydrogen 2.980 N/A SER 74.A N ARG 71.A O no hydrogen 3.260 N/A SER 74.A OG ASP 70.A O no hydrogen 2.702 N/A SER 75.A N PHE 72.A O no hydrogen 3.081 N/A MET 76.A N PHE 72.A O no hydrogen 2.933 N/A VAL 78.A N GLN 33.A OE1 no hydrogen 3.065 N/A ARG 80.A N ASP 35.A OD2 no hydrogen 2.862 N/A ARG 80.A NE ASP 35.A OD2 no hydrogen 3.200 N/A ARG 80.A NH2 ASP 35.A OD1 no hydrogen 3.039 N/A LYS 82.A N LEU 79.A O no hydrogen 2.893 N/A LEU 83.A N ARG 80.A O no hydrogen 3.254 N/A VAL 86.A N LYS 82.A O no hydrogen 3.220 N/A GLY 87.A N LEU 83.A O no hydrogen 3.001 N/A THR 88.A N GLN 84.A O no hydrogen 2.811 N/A THR 88.A OG1 GLN 84.A O no hydrogen 2.817 N/A ALA 89.A N LEU 85.A O no hydrogen 3.031 N/A ALA 90.A N VAL 86.A O no hydrogen 2.874 N/A MET 91.A N GLY 87.A O no hydrogen 2.966 N/A LEU 92.A N THR 88.A O no hydrogen 2.994 N/A LEU 93.A N ALA 89.A O no hydrogen 2.959 N/A ALA 94.A N ALA 90.A O no hydrogen 2.840 N/A SER 95.A N MET 91.A O no hydrogen 2.965 N/A SER 95.A OG MET 91.A O no hydrogen 2.798 N/A LYS 96.A N LEU 92.A O no hydrogen 2.927 N/A LYS 96.A NZ GLU 125.A OE1 no hydrogen 3.372 N/A LYS 96.A NZ GLU 125.A OE2 no hydrogen 2.701 N/A PHE 97.A N LEU 93.A O no hydrogen 2.870 N/A GLU 98.A N ALA 94.A O no hydrogen 2.896 N/A GLU 99.A N SER 95.A O no hydrogen 2.864 N/A GLU 104.A N GLU 107.A OE1 no hydrogen 2.865 N/A GLU 107.A N GLU 104.A O no hydrogen 2.900 N/A PHE 108.A N GLU 104.A O no hydrogen 3.352 N/A VAL 109.A N VAL 105.A O no hydrogen 2.998 N/A TYR 110.A N ALA 106.A O no hydrogen 2.849 N/A ILE 111.A N GLU 107.A O no hydrogen 2.983 N/A THR 112.A N VAL 109.A O no hydrogen 3.090 N/A THR 112.A OG1 VAL 109.A O no hydrogen 2.686 N/A ASP 113.A N TYR 110.A O no hydrogen 2.839 N/A THR 115.A N THR 112.A O no hydrogen 2.724 N/A THR 115.A OG1 THR 112.A O no hydrogen 2.717 N/A TYR 116.A OH GLY 81.A O no hydrogen 2.635 N/A THR 117.A N GLN 120.A OE1 no hydrogen 2.822 N/A THR 117.A OG1 GLN 120.A OE1 no hydrogen 3.462 N/A GLN 120.A N THR 117.A OG1 no hydrogen 3.048 N/A VAL 121.A N THR 117.A O no hydrogen 3.049 N/A LEU 122.A N LYS 118.A O no hydrogen 3.011 N/A ARG 123.A N LYS 119.A O no hydrogen 2.971 N/A MET 124.A N GLN 120.A O no hydrogen 2.949 N/A GLU 125.A N VAL 121.A O no hydrogen 2.856 N/A HIS 126.A N LEU 122.A O no hydrogen 3.143 N/A LEU 127.A N ARG 123.A O no hydrogen 2.969 N/A VAL 128.A N MET 124.A O no hydrogen 2.812 N/A LEU 129.A N GLU 125.A O no hydrogen 3.008 N/A LYS 130.A N HIS 126.A O no hydrogen 3.053 N/A VAL 131.A N LEU 127.A O no hydrogen 2.949 N/A LEU 132.A N VAL 128.A O no hydrogen 2.884 N/A THR 133.A N LYS 130.A O no hydrogen 3.140 N/A PHE 134.A N LEU 129.A O no hydrogen 2.933 N/A ASP 135.A N LEU 132.A O no hydrogen 2.938 N/A THR 140.A OG1 GLU 60.A OE1 no hydrogen 2.611 N/A THR 140.A OG1 GLU 60.A OE2 no hydrogen 3.242 N/A GLN 143.A N THR 140.A O no hydrogen 3.028 N/A GLN 143.A N THR 140.A OG1 no hydrogen 3.121 N/A GLN 143.A NE2 GLU 60.A OE2 no hydrogen 2.767 N/A GLN 143.A NE2 ALA 138.A O no hydrogen 3.085 N/A PHE 144.A N THR 140.A O no hydrogen 3.399 N/A PHE 144.A N ILE 141.A O no hydrogen 3.103 N/A LEU 145.A N ILE 141.A O no hydrogen 2.929 N/A THR 146.A N ASN 142.A O no hydrogen 3.079 N/A THR 146.A OG1 ASN 142.A O no hydrogen 3.460 N/A THR 146.A OG1 GLN 143.A O no hydrogen 3.439 N/A TYR 148.A N PHE 144.A O no hydrogen 2.904 N/A TYR 148.A OH SER 183.A O no hydrogen 2.712 N/A PHE 149.A N LEU 145.A O no hydrogen 2.831 N/A LEU 150.A N GLN 147.A O no hydrogen 3.168 N/A HIS 151.A N TYR 148.A O no hydrogen 2.961 N/A HIS 151.A ND1 SER 205.A OG no hydrogen 2.685 N/A GLN 152.A N PHE 149.A O no hydrogen 3.175 N/A GLN 152.A NE2 PHE 149.A O no hydrogen 2.993 N/A GLN 152.A NE2 GLU 160.A OE2 no hydrogen 2.952 N/A ASN 156.A N GLN 152.A OE1 no hydrogen 2.836 N/A VAL 159.A N ASN 156.A OD1 no hydrogen 3.064 N/A GLU 160.A N ASN 156.A O no hydrogen 3.178 N/A SER 161.A N CYS 157.A O no hydrogen 2.995 N/A SER 161.A OG HIS 249.A ND1 no hydrogen 2.908 N/A LEU 162.A N LYS 158.A O no hydrogen 2.878 N/A ALA 163.A N VAL 159.A O no hydrogen 2.948 N/A MET 164.A N GLU 160.A O no hydrogen 3.089 N/A PHE 165.A N SER 161.A O no hydrogen 2.917 N/A LEU 166.A N LEU 162.A O no hydrogen 2.981 N/A GLY 167.A N ALA 163.A O no hydrogen 2.995 N/A GLU 168.A N MET 164.A O no hydrogen 2.917 N/A LEU 169.A N PHE 165.A O no hydrogen 2.885 N/A SER 170.A N LEU 166.A O no hydrogen 3.261 N/A SER 170.A N GLY 167.A O no hydrogen 3.130 N/A SER 170.A OG GLY 167.A O no hydrogen 2.588 N/A LEU 171.A N GLU 168.A O no hydrogen 3.017 N/A ILE 172.A N LEU 169.A O no hydrogen 3.221 N/A TYR 177.A N ASP 173.A O no hydrogen 3.099 N/A TYR 177.A OH THR 227.A OG1 no hydrogen 2.488 N/A LEU 178.A N ALA 174.A O no hydrogen 2.996 N/A LYS 179.A N PRO 176.A O no hydrogen 3.131 N/A TYR 180.A N TYR 177.A O no hydrogen 2.977 N/A TYR 180.A OH ASP 223.A OD2 no hydrogen 2.608 N/A SER 183.A N GLU 20.A OE1 no hydrogen 2.881 N/A SER 183.A OG GLU 20.A OE1 no hydrogen 3.383 N/A SER 183.A OG GLU 20.A OE2 no hydrogen 2.472 N/A SER 183.A OG TYR 212.A OH no hydrogen 2.675 N/A VAL 184.A N LEU 181.A O no hydrogen 3.054 N/A ILE 185.A N LEU 181.A O no hydrogen 3.010 N/A ALA 186.A N PRO 182.A O no hydrogen 2.920 N/A ALA 187.A N SER 183.A O no hydrogen 3.100 N/A ALA 188.A N VAL 184.A O no hydrogen 2.862 N/A ALA 189.A N ILE 185.A O no hydrogen 2.793 N/A PHE 190.A N ALA 186.A O no hydrogen 2.917 N/A HIS 191.A N ALA 187.A O no hydrogen 2.956 N/A LEU 192.A N ALA 188.A O no hydrogen 2.874 N/A ALA 193.A N ALA 189.A O no hydrogen 2.917 N/A LEU 194.A N PHE 190.A O no hydrogen 2.820 N/A TYR 195.A N HIS 191.A O no hydrogen 2.855 N/A THR 196.A N LEU 192.A O no hydrogen 2.954 N/A THR 196.A OG1 LEU 192.A O no hydrogen 2.733 N/A VAL 197.A N ALA 193.A O no hydrogen 3.083 N/A THR 198.A N LEU 194.A O no hydrogen 2.837 N/A THR 198.A OG1 LEU 194.A O no hydrogen 2.739 N/A THR 198.A OG1 GLN 200.A OE1 no hydrogen 3.416 N/A GLY 199.A N TYR 195.A O no hydrogen 2.976 N/A GLN 200.A N THR 198.A OG1 no hydrogen 3.148 N/A TRP 202.A N HIS 191.A ND1 no hydrogen 3.137 N/A TRP 202.A NE1 TYR 212.A O no hydrogen 2.800 N/A SER 205.A OG HIS 151.A ND1 no hydrogen 2.685 N/A LEU 206.A N PRO 203.A O no hydrogen 2.939 N/A VAL 207.A N PRO 203.A O no hydrogen 3.159 N/A GLN 208.A N GLU 204.A O no hydrogen 2.983 N/A GLN 208.A NE2 GLU 204.A OE2 no hydrogen 2.894 N/A LYS 209.A N SER 205.A O no hydrogen 3.027 N/A THR 210.A N LEU 206.A O no hydrogen 2.860 N/A THR 210.A OG1 LEU 206.A O no hydrogen 2.702 N/A GLY 211.A N VAL 207.A O no hydrogen 2.883 N/A TYR 212.A N THR 210.A OG1 no hydrogen 2.811 N/A TYR 212.A OH SER 183.A OG no hydrogen 2.675 N/A THR 213.A N THR 216.A OG1 no hydrogen 3.025 N/A THR 216.A N THR 213.A OG1 no hydrogen 3.308 N/A THR 216.A OG1 THR 213.A O no hydrogen 3.160 N/A LEU 217.A N THR 213.A O no hydrogen 2.829 N/A LYS 218.A N GLU 215.A O no hydrogen 3.308 N/A LEU 221.A N LEU 217.A O no hydrogen 2.942 N/A LEU 222.A N LYS 218.A O no hydrogen 2.911 N/A ASP 223.A N PRO 219.A O no hydrogen 3.217 N/A LEU 224.A N CYS 220.A O no hydrogen 2.808 N/A HIS 225.A N LEU 221.A O no hydrogen 2.841 N/A GLN 226.A N LEU 222.A O no hydrogen 3.365 N/A THR 227.A N ASP 223.A O no hydrogen 2.872 N/A THR 227.A OG1 TYR 177.A OH no hydrogen 2.488 N/A THR 227.A OG1 ASP 223.A O no hydrogen 3.104 N/A TYR 228.A N LEU 224.A O no hydrogen 2.747 N/A LEU 229.A N HIS 225.A O no hydrogen 2.846 N/A ARG 230.A N GLN 226.A O no hydrogen 2.834 N/A ALA 231.A N TYR 228.A O no hydrogen 3.259 N/A GLN 233.A N ARG 230.A O no hydrogen 2.766 N/A GLN 233.A NE2 ARG 230.A O no hydrogen 3.542 N/A HIS 234.A N ALA 231.A O no hydrogen 3.299 N/A HIS 234.A NE2 ASP 173.A OD1 no hydrogen 2.768 N/A GLN 236.A N HIS 234.A ND1 no hydrogen 2.915 N/A GLN 237.A NE2 ALA 231.A O no hydrogen 2.853 N/A GLN 237.A NE2 HIS 234.A O no hydrogen 2.756 N/A SER 238.A N ASP 46.A OD2 no hydrogen 2.872 N/A SER 238.A OG ASP 46.A OD1 no hydrogen 2.577 N/A SER 238.A OG ASP 46.A OD2 no hydrogen 3.265 N/A ARG 240.A NH1 GLN 237.A OE1 no hydrogen 2.867 N/A GLU 241.A N GLN 237.A O no hydrogen 3.020 N/A LYS 242.A N SER 238.A O no hydrogen 2.922 N/A LYS 242.A NZ ASN 59.A OD1 no hydrogen 2.705 N/A LYS 242.A NZ GLU 168.A OE1 no hydrogen 3.128 N/A LYS 242.A NZ GLU 168.A OE2 no hydrogen 2.764 N/A TYR 243.A N ILE 239.A O no hydrogen 2.933 N/A TYR 243.A OH GLU 168.A OE1 no hydrogen 2.680 N/A LYS 244.A N GLU 241.A O no hydrogen 3.205 N/A LYS 244.A NZ GLU 241.A OE2 no hydrogen 3.442 N/A ASN 245.A N LYS 242.A O no hydrogen 3.166 N/A LYS 247.A N ASN 245.A OD1 no hydrogen 2.948 N/A TYR 248.A N ASN 245.A O no hydrogen 2.956 N/A HIS 249.A N SER 246.A O no hydrogen 2.738 N/A HIS 249.A ND1 SER 161.A OG no hydrogen 2.908 N/A GLY 250.A N ASN 245.A O no hydrogen 3.194 N/A VAL 251.A N TYR 248.A O no hydrogen 3.233 N/A SER 252.A N TYR 243.A O no hydrogen 3.266 N/A SER 252.A OG ARG 240.A O no hydrogen 2.757 N/A LEU 253.A N GLY 250.A O no hydrogen 2.979 N/A LEU 254.A N VAL 251.A O no hydrogen 3.089 N/A