Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4cqg_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 7.A N TYR 3.A O no hydrogen 3.052 N/A LYS 8.A N GLU 5.A O no hydrogen 3.326 N/A TYR 9.A N LEU 6.A O no hydrogen 2.983 N/A TYR 10.A N LEU 6.A O no hydrogen 2.932 N/A TYR 10.A OH HIS 73.A ND1 no hydrogen 2.670 N/A GLU 11.A N CYS 28.A O no hydrogen 2.958 N/A TYR 13.A N LEU 26.A O no hydrogen 2.848 N/A TYR 13.A OH GLU 11.A OE2 no hydrogen 2.928 N/A GLU 14.A N GLU 14.A OE1 no hydrogen 2.424 N/A ILE 16.A N VAL 24.A O no hydrogen 2.539 N/A GLY 17.A N VAL 24.A O no hydrogen 3.302 N/A GLY 19.A N ALA 22.A O no hydrogen 3.016 N/A LYS 23.A N ILE 40.A O no hydrogen 3.095 N/A VAL 24.A N GLY 17.A O no hydrogen 2.810 N/A LYS 25.A N ILE 38.A O no hydrogen 2.911 N/A LYS 25.A NZ TYR 13.A O no hydrogen 2.172 N/A LEU 26.A N GLU 14.A O no hydrogen 2.946 N/A ALA 27.A N VAL 36.A O no hydrogen 2.776 N/A CYS 28.A N GLU 11.A O no hydrogen 2.800 N/A CYS 28.A SG HIS 29.A O no hydrogen 3.783 N/A CYS 28.A SG GLU 34.A O no hydrogen 3.928 N/A HIS 29.A N GLU 34.A O no hydrogen 2.874 N/A HIS 29.A ND1 THR 32.A OG1 no hydrogen 2.659 N/A VAL 30.A N TYR 9.A O no hydrogen 3.064 N/A THR 32.A N HIS 29.A ND1 no hydrogen 3.199 N/A THR 32.A OG1 HIS 29.A ND1 no hydrogen 2.659 N/A GLY 33.A N HIS 29.A O no hydrogen 2.726 N/A GLU 34.A N THR 32.A OG1 no hydrogen 3.188 N/A VAL 36.A N ALA 27.A O no hydrogen 3.009 N/A ALA 37.A N LEU 85.A O no hydrogen 2.858 N/A ILE 38.A N LYS 25.A O no hydrogen 2.765 N/A LYS 39.A N MET 83.A O no hydrogen 2.800 N/A LYS 39.A NZ GLU 56.A OE1 no hydrogen 3.071 N/A LYS 39.A NZ GLU 56.A OE2 no hydrogen 3.232 N/A ILE 40.A N LYS 23.A O no hydrogen 2.873 N/A MET 41.A N ILE 81.A O no hydrogen 2.804 N/A LYS 43.A N ASN 79.A O no hydrogen 2.707 N/A LYS 43.A NZ THR 77.A O no hydrogen 2.207 N/A LYS 43.A NZ LYS 78.A O no hydrogen 2.986 N/A ALA 45.A N ASP 42.A OD2 no hydrogen 2.442 N/A LEU 46.A N ASP 42.A O no hydrogen 2.825 N/A GLY 47.A N LYS 43.A O no hydrogen 2.932 N/A ASP 49.A N LEU 46.A O no hydrogen 3.031 N/A LEU 50.A N GLY 47.A O no hydrogen 3.470 N/A ARG 52.A N ASP 49.A O no hydrogen 3.057 N/A VAL 53.A N LEU 50.A O no hydrogen 2.980 N/A LYS 54.A N LEU 50.A O no hydrogen 3.354 N/A THR 55.A N PRO 51.A O no hydrogen 2.963 N/A THR 55.A OG1 PRO 51.A O no hydrogen 3.457 N/A GLU 56.A N ARG 52.A O no hydrogen 3.030 N/A ILE 57.A N VAL 53.A O no hydrogen 2.958 N/A ASP 58.A N LYS 54.A O no hydrogen 3.164 N/A ALA 59.A N THR 55.A O no hydrogen 3.113 N/A LEU 60.A N GLU 56.A O no hydrogen 2.976 N/A LYS 61.A N ILE 57.A O no hydrogen 2.993 N/A SER 62.A N ALA 59.A O no hydrogen 3.064 N/A SER 62.A OG ASP 58.A O no hydrogen 2.641 N/A LEU 63.A N LEU 60.A O no hydrogen 3.306 N/A ARG 64.A N TYR 121.A OH no hydrogen 3.251 N/A ARG 64.A NE THR 259.A O no hydrogen 2.806 N/A ARG 64.A NH1 GLN 70.A OE1 no hydrogen 2.979 N/A HIS 65.A NE2 TRP 255.A O no hydrogen 2.927 N/A GLN 66.A NE2 GLN 256.A O no hydrogen 3.518 N/A HIS 67.A N HIS 65.A ND1 no hydrogen 3.018 N/A HIS 67.A ND1 LEU 145.A O no hydrogen 2.665 N/A ILE 68.A N HIS 65.A O no hydrogen 3.298 N/A CYS 69.A N LEU 147.A O no hydrogen 3.137 N/A CYS 69.A SG GLU 86.A O no hydrogen 3.598 N/A GLN 70.A N GLU 86.A OE1 no hydrogen 3.058 N/A GLN 70.A NE2 LEU 71.A O no hydrogen 2.970 N/A TYR 72.A N VAL 84.A O no hydrogen 2.776 N/A HIS 73.A ND1 TYR 10.A OH no hydrogen 2.670 N/A VAL 74.A N TYR 292.A O no hydrogen 2.911 N/A LEU 75.A N PHE 82.A O no hydrogen 3.047 N/A THR 77.A N LYS 80.A O no hydrogen 3.061 N/A ASN 79.A N ASP 2.A OD2 no hydrogen 3.311 N/A ASN 79.A ND2 ASP 2.A OD2 no hydrogen 3.184 N/A LYS 80.A N THR 77.A OG1 no hydrogen 3.280 N/A ILE 81.A N MET 41.A O no hydrogen 2.704 N/A PHE 82.A N LEU 75.A O no hydrogen 2.883 N/A MET 83.A N LYS 39.A O no hydrogen 2.862 N/A VAL 84.A N HIS 73.A O no hydrogen 2.934 N/A LEU 85.A N ALA 37.A O no hydrogen 2.677 N/A GLU 86.A N GLN 70.A O no hydrogen 2.966 N/A CYS 88.A SG GLU 86.A O no hydrogen 3.838 N/A GLY 90.A N PHE 139.A O no hydrogen 2.870 N/A GLY 91.A N CYS 88.A O no hydrogen 3.414 N/A LEU 93.A N LEU 137.A O no hydrogen 2.788 N/A PHE 94.A N PRO 134.A O no hydrogen 3.107 N/A TYR 96.A OH GLU 107.A OE2 no hydrogen 2.566 N/A ILE 97.A N LEU 93.A O no hydrogen 2.973 N/A ILE 98.A N PHE 94.A O no hydrogen 3.280 N/A SER 99.A N ASP 95.A O no hydrogen 3.132 N/A SER 99.A OG TYR 96.A O no hydrogen 2.657 N/A GLN 100.A N TYR 96.A O no hydrogen 3.244 N/A GLN 100.A N ILE 97.A O no hydrogen 3.273 N/A GLN 100.A NE2 SER 99.A OG no hydrogen 3.311 N/A ASP 101.A N ILE 98.A O no hydrogen 3.258 N/A ARG 102.A N GLN 100.A O no hydrogen 2.710 N/A LEU 103.A N LEU 184.A O no hydrogen 2.800 N/A GLU 107.A N SER 104.A OG no hydrogen 3.183 N/A THR 108.A N SER 104.A O no hydrogen 2.780 N/A THR 108.A OG1 SER 104.A O no hydrogen 3.114 N/A ARG 109.A N GLU 105.A O no hydrogen 3.070 N/A ARG 109.A NE TRP 244.A O no hydrogen 2.842 N/A ARG 109.A NH2 GLU 105.A OE2 no hydrogen 3.022 N/A ARG 109.A NH2 TRP 244.A O no hydrogen 3.267 N/A VAL 111.A N GLU 107.A O no hydrogen 3.294 N/A PHE 112.A N THR 108.A O no hydrogen 2.870 N/A ARG 113.A N ARG 109.A O no hydrogen 3.139 N/A ARG 113.A NH1 VAL 245.A O no hydrogen 2.796 N/A ARG 113.A NH2 CYS 251.A O no hydrogen 2.426 N/A GLN 114.A N VAL 110.A O no hydrogen 3.488 N/A GLN 114.A NE2 VAL 110.A O no hydrogen 3.170 N/A ILE 115.A N VAL 111.A O no hydrogen 3.059 N/A LEU 116.A N PHE 112.A O no hydrogen 2.937 N/A SER 117.A N ARG 113.A O no hydrogen 2.925 N/A SER 117.A OG GLU 254.A O no hydrogen 3.267 N/A ALA 118.A N GLN 114.A O no hydrogen 3.236 N/A VAL 119.A N ILE 115.A O no hydrogen 2.870 N/A ALA 120.A N LEU 116.A O no hydrogen 2.806 N/A TYR 121.A N SER 117.A O no hydrogen 3.098 N/A VAL 122.A N ALA 118.A O no hydrogen 2.872 N/A HIS 123.A N VAL 119.A O no hydrogen 3.180 N/A HIS 123.A NE2 ASP 173.A OD2 no hydrogen 2.726 N/A SER 124.A N ALA 120.A O no hydrogen 2.950 N/A SER 124.A OG TYR 121.A O no hydrogen 2.852 N/A GLN 125.A N TYR 121.A O no hydrogen 3.242 N/A GLN 125.A N VAL 122.A O no hydrogen 3.161 N/A GLN 125.A NE2 SER 124.A OG no hydrogen 2.903 N/A GLY 126.A N HIS 123.A O no hydrogen 2.669 N/A TYR 127.A N VAL 122.A O no hydrogen 3.157 N/A ALA 128.A N ALA 154.A O no hydrogen 2.961 N/A HIS 129.A N ASP 173.A OD2 no hydrogen 2.940 N/A HIS 129.A NE2 ILE 148.A O no hydrogen 2.914 N/A ARG 130.A N ASP 173.A OD1 no hydrogen 3.045 N/A ASP 131.A N HIS 129.A ND1 no hydrogen 3.136 N/A GLU 135.A N GLU 135.A OE1 no hydrogen 2.708 N/A ASN 136.A N LYS 133.A O no hydrogen 2.984 N/A ASN 136.A ND2 ASP 131.A O no hydrogen 2.685 N/A LEU 138.A N LYS 146.A O no hydrogen 2.912 N/A PHE 139.A N GLY 91.A O no hydrogen 3.007 N/A ASP 140.A N LYS 144.A O no hydrogen 2.874 N/A GLU 141.A N GLU 141.A OE1 no hydrogen 3.058 N/A ASN 142.A N ASP 140.A OD1 no hydrogen 2.940 N/A HIS 143.A N ASP 140.A O no hydrogen 2.951 N/A LYS 144.A N ASP 140.A OD1 no hydrogen 3.031 N/A LEU 145.A N GLN 114.A OE1 no hydrogen 3.085 N/A LYS 146.A N LEU 138.A O no hydrogen 2.631 N/A LYS 146.A NZ GLN 66.A O no hydrogen 2.829 N/A LYS 146.A NZ GLU 86.A OE2 no hydrogen 3.060 N/A LEU 147.A N HIS 67.A O no hydrogen 2.729 N/A ILE 148.A N ASN 136.A O no hydrogen 3.114 N/A PHE 150.A N GLU 56.A OE2 no hydrogen 3.369 N/A CYS 153.A N PHE 150.A O no hydrogen 3.117 N/A CYS 153.A SG ALA 128.A O no hydrogen 3.581 N/A ALA 154.A N ALA 128.A O no hydrogen 3.061 N/A CYS 156.A SG ARG 130.A O no hydrogen 3.961 N/A SER 158.A N ASP 131.A OD1 no hydrogen 3.394 N/A TYR 161.A N SER 158.A O no hydrogen 3.208 N/A ALA 162.A N LEU 159.A O no hydrogen 3.087 N/A GLU 165.A N GLU 165.A OE1 no hydrogen 2.776 N/A LEU 166.A N ALA 163.A O no hydrogen 2.881 N/A ILE 167.A N PRO 164.A O no hydrogen 3.208 N/A GLU 171.A N GLU 171.A OE1 no hydrogen 3.245 N/A ASP 173.A N GLY 169.A O no hydrogen 3.307 N/A VAL 174.A N SER 170.A O no hydrogen 3.278 N/A TRP 175.A N GLU 171.A O no hydrogen 3.214 N/A SER 176.A N ALA 172.A O no hydrogen 3.133 N/A SER 176.A OG TYR 161.A O no hydrogen 2.873 N/A SER 176.A OG ALA 172.A O no hydrogen 3.178 N/A MET 177.A N ASP 173.A O no hydrogen 3.040 N/A GLY 178.A N VAL 174.A O no hydrogen 3.051 N/A ILE 179.A N TRP 175.A O no hydrogen 3.028 N/A LEU 180.A N SER 176.A O no hydrogen 2.902 N/A LEU 181.A N MET 177.A O no hydrogen 2.989 N/A TYR 182.A N GLY 178.A O no hydrogen 3.203 N/A TYR 182.A OH GLU 209.A O no hydrogen 2.145 N/A VAL 183.A N ILE 179.A O no hydrogen 3.151 N/A LEU 184.A N LEU 180.A O no hydrogen 2.987 N/A MET 185.A N LEU 181.A O no hydrogen 3.286 N/A CYS 186.A N TYR 182.A O no hydrogen 2.749 N/A GLY 187.A N VAL 183.A O no hydrogen 2.771 N/A ASN 195.A N ASP 193.A OD1 no hydrogen 2.965 N/A ALA 198.A N ASN 195.A OD1 no hydrogen 2.851 N/A LEU 199.A N ASN 195.A O no hydrogen 2.859 N/A TYR 200.A N VAL 196.A O no hydrogen 2.818 N/A TYR 200.A OH GLN 168.A OE1 no hydrogen 3.310 N/A LYS 201.A N MET 197.A O no hydrogen 3.121 N/A LYS 202.A N ALA 198.A O no hydrogen 3.133 N/A LYS 202.A NZ ASP 192.A O no hydrogen 2.783 N/A LYS 202.A NZ ASP 193.A OD2 no hydrogen 2.914 N/A ILE 203.A N LEU 199.A O no hydrogen 2.998 N/A MET 204.A N TYR 200.A O no hydrogen 3.176 N/A ARG 205.A N LYS 201.A O no hydrogen 2.980 N/A GLY 206.A N LYS 202.A O no hydrogen 2.931 N/A TRP 213.A NE1 MET 185.A O no hydrogen 3.055 N/A LEU 214.A N PRO 211.A O no hydrogen 3.218 N/A SER 215.A OG GLU 105.A OE1 no hydrogen 3.452 N/A SER 215.A OG SER 218.A OG no hydrogen 3.146 N/A SER 217.A OG GLN 247.A OE1 no hydrogen 3.421 N/A SER 218.A N SER 215.A OG no hydrogen 2.994 N/A SER 218.A OG SER 215.A O no hydrogen 3.082 N/A SER 218.A OG SER 215.A OG no hydrogen 3.146 N/A ILE 219.A N SER 215.A O no hydrogen 3.052 N/A LEU 220.A N PRO 216.A O no hydrogen 3.037 N/A LEU 221.A N SER 217.A O no hydrogen 3.104 N/A LEU 222.A N SER 218.A O no hydrogen 2.907 N/A GLN 223.A N ILE 219.A O no hydrogen 3.042 N/A GLN 224.A N LEU 220.A O no hydrogen 2.896 N/A MET 225.A N LEU 221.A O no hydrogen 2.882 N/A LEU 226.A N LEU 222.A O no hydrogen 2.701 N/A GLN 227.A NE2 GLN 223.A O no hydrogen 3.345 N/A LYS 231.A N ASP 229.A OD1 no hydrogen 3.172 N/A LYS 232.A N ASP 229.A O no hydrogen 2.894 N/A ARG 233.A N ASP 229.A O no hydrogen 3.192 N/A ARG 233.A N PRO 230.A O no hydrogen 3.051 N/A ARG 233.A NE GLN 227.A O no hydrogen 2.645 N/A ARG 233.A NH1 GLU 165.A OE1 no hydrogen 3.280 N/A ARG 233.A NH1 GLU 165.A OE2 no hydrogen 2.486 N/A ARG 233.A NH1 GLU 171.A O no hydrogen 2.908 N/A ARG 233.A NH2 GLU 165.A OE1 no hydrogen 2.787 N/A ARG 233.A NH2 GLN 227.A O no hydrogen 2.738 N/A ILE 234.A N GLN 224.A O no hydrogen 3.171 N/A ASN 238.A ND2 SER 235.A OG no hydrogen 3.195 N/A LEU 239.A N SER 235.A O no hydrogen 3.130 N/A LEU 240.A N MET 236.A O no hydrogen 3.077 N/A LEU 240.A N ARG 237.A O no hydrogen 3.273 N/A HIS 242.A N LEU 239.A O no hydrogen 3.275 N/A HIS 242.A NE2 GLN 224.A OE1 no hydrogen 2.818 N/A TRP 244.A N HIS 242.A ND1 no hydrogen 3.120 N/A MET 246.A N HIS 242.A O no hydrogen 3.023 N/A GLN 247.A N TRP 244.A O no hydrogen 3.205 N/A TYR 249.A N MET 246.A O no hydrogen 2.639 N/A CYS 251.A SG PRO 252.A O no hydrogen 3.510 N/A CYS 251.A SG GLU 254.A OE1 no hydrogen 3.275 N/A GLN 256.A N GLN 256.A OE1 no hydrogen 2.841 N/A SER 257.A OG ARG 64.A O no hydrogen 3.212 N/A LYS 258.A N GLN 66.A OE1 no hydrogen 2.805 N/A LYS 258.A NZ GLU 254.A OE2 no hydrogen 3.058 N/A THR 259.A N SER 257.A OG no hydrogen 3.054 N/A THR 262.A OG1 HIS 263.A ND1 no hydrogen 3.321 N/A HIS 263.A ND1 THR 262.A OG1 no hydrogen 3.321 N/A ASP 265.A N TYR 299.A OH no hydrogen 2.968 N/A CYS 268.A N ASP 265.A OD2 no hydrogen 3.082 N/A CYS 268.A SG ASP 265.A OD2 no hydrogen 3.388 N/A VAL 269.A N ASP 265.A O no hydrogen 2.861 N/A THR 270.A N GLU 266.A O no hydrogen 2.820 N/A THR 270.A OG1 GLU 266.A O no hydrogen 2.541 N/A GLU 271.A N ASP 267.A O no hydrogen 3.040 N/A LEU 272.A N CYS 268.A O no hydrogen 3.011 N/A SER 273.A N VAL 269.A O no hydrogen 2.839 N/A SER 273.A OG VAL 269.A O no hydrogen 3.205 N/A SER 273.A OG THR 270.A O no hydrogen 2.597 N/A VAL 274.A N THR 270.A O no hydrogen 3.175 N/A HIS 276.A N LEU 272.A O no hydrogen 2.970 N/A SER 278.A N SER 273.A O no hydrogen 3.148 N/A SER 278.A OG HIS 276.A O no hydrogen 3.481 N/A SER 279.A OG THR 282.A OG1 no hydrogen 3.074 N/A GLN 281.A NE2 GLN 281.A O no hydrogen 3.095 N/A THR 282.A N SER 279.A OG no hydrogen 3.135 N/A THR 282.A OG1 SER 279.A OG no hydrogen 3.074 N/A MET 283.A N SER 279.A O no hydrogen 2.834 N/A GLU 284.A N ARG 280.A O no hydrogen 2.898 N/A ASP 285.A N GLN 281.A O no hydrogen 3.346 N/A LEU 286.A N THR 282.A O no hydrogen 3.116 N/A ILE 287.A N MET 283.A O no hydrogen 2.983 N/A SER 288.A N GLU 284.A O no hydrogen 3.374 N/A SER 288.A OG GLU 284.A O no hydrogen 2.739 N/A SER 289.A N LEU 286.A O no hydrogen 3.266 N/A SER 289.A OG LEU 286.A O no hydrogen 3.387 N/A TRP 290.A N ILE 287.A O no hydrogen 2.940 N/A GLN 291.A NE2 SER 289.A O no hydrogen 2.857 N/A TYR 292.A N THR 296.A OG1 no hydrogen 3.195 N/A THR 296.A N ASP 293.A OD1 no hydrogen 3.259 N/A THR 296.A OG1 ASP 293.A OD1 no hydrogen 3.418 N/A ALA 297.A N ASP 293.A O no hydrogen 2.923 N/A THR 298.A N HIS 294.A O no hydrogen 3.050 N/A THR 298.A OG1 HIS 294.A O no hydrogen 2.581 N/A TYR 299.A N LEU 295.A O no hydrogen 3.018 N/A LEU 300.A N THR 296.A O no hydrogen 3.051 N/A LEU 301.A N ALA 297.A O no hydrogen 2.836 N/A LEU 302.A N THR 298.A O no hydrogen 2.956 N/A LEU 303.A N TYR 299.A O no hydrogen 2.830 N/A ALA 304.A N LEU 300.A O no hydrogen 2.930 N/A LYS 305.A N LEU 301.A O no hydrogen 2.951 N/A LYS 305.A NZ THR 32.A O no hydrogen 3.181 N/A LYS 306.A N LEU 302.A O no hydrogen 2.946 N/A LYS 306.A NZ ASP 265.A OD1 no hydrogen 3.099 N/A ALA 307.A N LEU 303.A O no hydrogen 2.954 N/A ARG 308.A N ALA 304.A O no hydrogen 3.092 N/A ARG 308.A NH1 GLU 34.A OE1 no hydrogen 2.818 N/A ARG 308.A NH1 GLU 34.A OE2 no hydrogen 3.431 N/A ARG 308.A NH2 GLU 34.A OE2 no hydrogen 3.273 N/A LEU 309.A N LYS 305.A O no hydrogen 3.174 N/A GLU 310.A N LYS 306.A O no hydrogen 2.951 N/A HIS 311.A N ALA 307.A O no hydrogen 3.224 N/A HIS 311.A N ARG 308.A O no hydrogen 3.252 N/A HIS 312.A N LEU 309.A O no hydrogen 2.993 N/A HIS 312.A ND1 ARG 308.A O no hydrogen 2.959 N/A