Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4d4u_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 1.A OG THR 2.A O no hydrogen 3.393 N/A SER 1.A OG TYR 288.A O no hydrogen 2.862 N/A THR 2.A OG1 ALA 313.A OXT no hydrogen 3.118 N/A ALA 5.A N THR 2.A OG1 no hydrogen 3.010 N/A GLN 6.A N THR 2.A O no hydrogen 2.913 N/A GLN 7.A N GLY 4.A O no hydrogen 3.022 N/A VAL 8.A N ALA 5.A O no hydrogen 3.036 N/A LEU 9.A N GLN 28.A O no hydrogen 3.181 N/A ARG 11.A N GLN 284.A OE1 no hydrogen 2.762 N/A ARG 11.A NE GLN 260.A O no hydrogen 2.834 N/A ARG 11.A NH2 GLN 260.A O no hydrogen 3.153 N/A THR 12.A N LEU 9.A O no hydrogen 3.158 N/A THR 12.A OG1 GLY 13.A O no hydrogen 2.737 N/A THR 12.A OG1 GLN 28.A O no hydrogen 3.391 N/A ALA 15.A N TYR 26.A O no hydrogen 3.068 N/A VAL 17.A N ARG 24.A O no hydrogen 3.049 N/A ASN 18.A ND2 THR 20.A O no hydrogen 2.783 N/A ASN 18.A ND2 SER 268.A O no hydrogen 3.323 N/A SER 19.A N HIS 22.A O no hydrogen 2.944 N/A SER 19.A OG GLU 67.A OE1 no hydrogen 2.504 N/A THR 20.A OG1 SER 19.A O no hydrogen 2.988 N/A HIS 22.A N SER 19.A O no hydrogen 2.697 N/A HIS 22.A ND1 GLU 40.A OE1 no hydrogen 2.657 N/A LEU 23.A N TYR 39.A O no hydrogen 3.066 N/A ARG 24.A N VAL 17.A O no hydrogen 2.993 N/A ARG 24.A NH1 LEU 23.A O no hydrogen 2.973 N/A ARG 24.A NH1 GLU 40.A OE2 no hydrogen 2.853 N/A ARG 24.A NH2 GLU 40.A OE2 no hydrogen 2.850 N/A VAL 25.A N SER 37.A O no hydrogen 2.797 N/A TYR 26.A N ALA 15.A O no hydrogen 2.864 N/A TYR 26.A OH GLU 36.A OE2 no hydrogen 2.736 N/A PHE 27.A N ARG 35.A O no hydrogen 3.145 N/A GLN 28.A N THR 12.A OG1 no hydrogen 2.745 N/A GLN 28.A NE2 GLY 32.A O no hydrogen 2.801 N/A GLN 28.A NE2 LYS 56.A O no hydrogen 2.834 N/A ASP 29.A N SER 33.A O no hydrogen 2.848 N/A VAL 30.A N GLN 7.A O no hydrogen 3.040 N/A TYR 31.A N ASP 29.A OD1 no hydrogen 2.866 N/A GLY 32.A N ASP 29.A O no hydrogen 2.974 N/A SER 33.A N ASP 29.A OD1 no hydrogen 3.096 N/A SER 33.A OG ASN 54.A OD1 no hydrogen 2.438 N/A ILE 34.A N GLY 53.A O no hydrogen 2.783 N/A ARG 35.A N PHE 27.A O no hydrogen 2.872 N/A ARG 35.A NE ASP 29.A OD2 no hydrogen 3.024 N/A ARG 35.A NH1 GLN 7.A OE1 no hydrogen 2.865 N/A ARG 35.A NH1 GLY 46.A O no hydrogen 2.802 N/A ARG 35.A NH2 GLN 7.A OE1 no hydrogen 3.380 N/A ARG 35.A NH2 ASP 29.A OD2 no hydrogen 3.203 N/A GLU 36.A N ASN 50.A O no hydrogen 3.055 N/A SER 37.A N VAL 25.A O no hydrogen 2.748 N/A SER 37.A OG PRO 311.A O no hydrogen 2.587 N/A LEU 38.A N ALA 44.A O no hydrogen 2.939 N/A TYR 39.A N LEU 23.A O no hydrogen 2.933 N/A GLU 40.A N SER 42.A O no hydrogen 3.127 N/A ALA 44.A N LEU 38.A O no hydrogen 2.950 N/A GLY 46.A N GLU 36.A O no hydrogen 2.963 N/A THR 47.A N ASN 50.A OD1 no hydrogen 2.782 N/A THR 47.A OG1 ASN 50.A OD1 no hydrogen 2.913 N/A LYS 49.A N THR 47.A OG1 no hydrogen 3.012 N/A ASN 50.A N THR 47.A O no hydrogen 2.792 N/A ILE 52.A N ILE 34.A O no hydrogen 2.909 N/A ALA 55.A N GLY 32.A O no hydrogen 3.213 N/A LYS 56.A N LEU 76.A O no hydrogen 2.974 N/A LYS 56.A NZ ASN 80.A OD1 no hydrogen 2.877 N/A LYS 56.A NZ PRO 107.A O no hydrogen 2.837 N/A GLY 58.A N GLN 28.A OE1 no hydrogen 3.153 N/A SER 59.A N LYS 56.A O no hydrogen 2.984 N/A SER 59.A OG PRO 60.A O no hydrogen 2.570 N/A ALA 62.A N TYR 74.A O no hydrogen 2.966 N/A THR 64.A N ARG 72.A O no hydrogen 2.991 N/A SER 65.A OG GLU 67.A O no hydrogen 2.793 N/A LYS 66.A N HIS 70.A O no hydrogen 2.933 N/A LYS 66.A NZ THR 119.A O no hydrogen 2.787 N/A LYS 69.A N LYS 66.A O no hydrogen 3.051 N/A HIS 70.A N LYS 66.A O no hydrogen 3.423 N/A HIS 70.A ND1 ASP 88.A OD1 no hydrogen 2.688 N/A ILE 71.A N TYR 87.A O no hydrogen 2.893 N/A ARG 72.A N THR 64.A O no hydrogen 2.931 N/A ARG 72.A NH1 ILE 71.A O no hydrogen 2.982 N/A ARG 72.A NH1 ASP 88.A OD1 no hydrogen 2.967 N/A ARG 72.A NH2 ASP 88.A OD1 no hydrogen 2.939 N/A VAL 73.A N PHE 85.A O no hydrogen 2.887 N/A TYR 74.A N ALA 62.A O no hydrogen 2.604 N/A TYR 74.A OH GLU 84.A OE2 no hydrogen 2.675 N/A THR 75.A N GLN 83.A O no hydrogen 3.307 N/A LEU 76.A N SER 59.A OG no hydrogen 3.053 N/A THR 77.A N THR 81.A O no hydrogen 3.063 N/A THR 77.A OG1 THR 81.A O no hydrogen 3.321 N/A THR 77.A OG1 THR 81.A OG1 no hydrogen 2.655 N/A ASN 80.A N THR 77.A O no hydrogen 3.170 N/A THR 81.A N THR 77.A OG1 no hydrogen 3.091 N/A THR 81.A OG1 THR 77.A OG1 no hydrogen 2.655 N/A LEU 82.A N PHE 103.A O no hydrogen 3.180 N/A GLN 83.A N THR 75.A O no hydrogen 2.992 N/A GLN 83.A NE2 ASN 54.A O no hydrogen 2.911 N/A GLN 83.A NE2 THR 75.A OG1 no hydrogen 2.890 N/A PHE 85.A N VAL 73.A O no hydrogen 2.769 N/A ALA 86.A N TYR 94.A O no hydrogen 2.850 N/A TYR 87.A N ILE 71.A O no hydrogen 2.850 N/A ASP 88.A N GLY 92.A O no hydrogen 3.293 N/A SER 89.A N LYS 69.A O no hydrogen 2.768 N/A THR 91.A N ASP 88.A O no hydrogen 2.843 N/A GLY 92.A N ASP 88.A O no hydrogen 3.027 N/A TYR 94.A N ALA 86.A O no hydrogen 2.846 N/A TYR 94.A OH ASP 88.A OD2 no hydrogen 2.567 N/A GLY 96.A N GLU 84.A O no hydrogen 2.935 N/A GLY 100.A N GLY 97.A O no hydrogen 3.004 N/A ALA 101.A N LEU 98.A O no hydrogen 2.916 N/A LYS 102.A N GLY 99.A O no hydrogen 3.099 N/A GLN 104.A NE2 GLY 79.A O no hydrogen 2.788 N/A VAL 105.A N ASN 80.A O no hydrogen 2.951 N/A ALA 106.A N GLN 129.A O no hydrogen 2.882 N/A TYR 108.A OH ASN 133.A OD1 no hydrogen 2.610 N/A SER 109.A N ALA 106.A O no hydrogen 3.012 N/A SER 109.A OG CYS 110.A O no hydrogen 2.745 N/A SER 109.A OG GLN 129.A O no hydrogen 3.447 N/A CYS 110.A SG THR 158.A O no hydrogen 3.289 N/A ALA 112.A N TYR 127.A O no hydrogen 3.025 N/A VAL 114.A N ARG 125.A O no hydrogen 2.943 N/A PHE 115.A N THR 64.A OG1 no hydrogen 3.157 N/A LEU 116.A N GLN 123.A O no hydrogen 2.847 N/A ALA 117.A N SER 164.A OG no hydrogen 3.063 N/A ALA 121.A N THR 119.A OG1 no hydrogen 2.900 N/A LEU 124.A N TRP 140.A O no hydrogen 2.960 N/A ARG 125.A N VAL 114.A O no hydrogen 3.011 N/A ARG 125.A NH1 LEU 124.A O no hydrogen 3.026 N/A ARG 125.A NH1 ASN 141.A OD1 no hydrogen 2.836 N/A ARG 125.A NH2 ASN 141.A OD1 no hydrogen 3.230 N/A ILE 126.A N TYR 138.A O no hydrogen 2.882 N/A TYR 127.A N ALA 112.A O no hydrogen 2.877 N/A TYR 127.A OH GLU 137.A OE2 no hydrogen 2.700 N/A ALA 128.A N GLN 136.A O no hydrogen 3.118 N/A GLN 129.A N SER 109.A OG no hydrogen 2.783 N/A GLN 129.A NE2 ASN 133.A O no hydrogen 3.124 N/A GLN 129.A NE2 LEU 155.A O no hydrogen 3.011 N/A LYS 130.A N THR 134.A O no hydrogen 2.970 N/A LYS 130.A NZ GLN 136.A OE1 no hydrogen 3.337 N/A LYS 130.A NZ GLU 147.A OE1 no hydrogen 3.072 N/A ASN 133.A N LYS 130.A O no hydrogen 2.730 N/A THR 134.A N ASP 132.A OD1 no hydrogen 2.773 N/A THR 134.A OG1 ASP 132.A OD1 no hydrogen 2.618 N/A THR 134.A OG1 ASP 132.A OD2 no hydrogen 3.435 N/A ILE 135.A N GLY 152.A O no hydrogen 2.883 N/A GLN 136.A N ALA 128.A O no hydrogen 2.809 N/A GLN 136.A NE2 GLU 137.A O no hydrogen 3.022 N/A GLN 136.A NE2 GLY 148.A O no hydrogen 3.176 N/A GLU 137.A N THR 149.A O no hydrogen 3.057 N/A TYR 138.A N ILE 126.A O no hydrogen 2.676 N/A MET 139.A N LYS 146.A O no hydrogen 2.701 N/A TRP 140.A N LEU 124.A O no hydrogen 2.988 N/A LYS 146.A N MET 139.A O no hydrogen 2.977 N/A LYS 146.A NZ ASP 143.A O no hydrogen 3.040 N/A GLY 148.A N GLU 137.A O no hydrogen 2.696 N/A THR 149.A N GLU 137.A OE1 no hydrogen 3.021 N/A ASN 150.A ND2 THR 134.A OG1 no hydrogen 3.019 N/A ASN 150.A ND2 GLN 136.A OE1 no hydrogen 2.918 N/A LEU 151.A N ILE 135.A O no hydrogen 2.857 N/A GLY 152.A N ASN 150.A OD1 no hydrogen 2.905 N/A ALA 154.A N ASN 133.A O no hydrogen 2.840 N/A LEU 155.A N GLN 180.A O no hydrogen 3.047 N/A GLY 157.A N GLN 129.A OE1 no hydrogen 2.796 N/A THR 158.A N LEU 155.A O no hydrogen 3.008 N/A THR 158.A OG1 GLY 159.A O no hydrogen 2.789 N/A THR 158.A OG1 GLN 180.A O no hydrogen 3.545 N/A GLY 161.A N TRP 178.A O no hydrogen 2.898 N/A THR 163.A N ARG 176.A O no hydrogen 2.874 N/A THR 163.A OG1 SER 218.A OG no hydrogen 2.694 N/A SER 164.A OG SER 174.A O no hydrogen 2.904 N/A PHE 165.A N SER 174.A O no hydrogen 3.219 N/A ARG 166.A NE TYR 170.A O no hydrogen 3.350 N/A ARG 166.A NH2 TYR 170.A O no hydrogen 3.320 N/A THR 168.A N GLY 222.A O no hydrogen 2.738 N/A THR 168.A OG1 ASN 223.A OD1 no hydrogen 2.740 N/A TYR 170.A N TYR 167.A O no hydrogen 3.192 N/A SER 174.A N PHE 165.A O no hydrogen 2.796 N/A SER 174.A OG ASP 192.A OD1 no hydrogen 2.823 N/A ILE 175.A N TYR 191.A O no hydrogen 2.951 N/A ARG 176.A N THR 163.A O no hydrogen 2.994 N/A ARG 176.A NH1 ILE 175.A O no hydrogen 2.783 N/A ARG 176.A NH1 TYR 191.A O no hydrogen 3.005 N/A ARG 176.A NH1 ASP 192.A OD1 no hydrogen 3.180 N/A ARG 176.A NH2 ASP 192.A OD1 no hydrogen 2.917 N/A ARG 176.A NH2 ASP 192.A OD2 no hydrogen 3.453 N/A ILE 177.A N ARG 189.A O no hydrogen 3.023 N/A TRP 178.A N GLY 161.A O no hydrogen 2.777 N/A TRP 178.A NE1 TYR 249.A OH no hydrogen 2.865 N/A PHE 179.A N VAL 187.A O no hydrogen 3.059 N/A GLN 180.A N THR 158.A OG1 no hydrogen 2.701 N/A GLN 180.A NE2 LEU 184.A O no hydrogen 3.000 N/A GLN 180.A NE2 ALA 208.A O no hydrogen 3.086 N/A GLN 180.A NE2 PRO 209.A O no hydrogen 3.062 N/A THR 181.A N LYS 185.A O no hydrogen 2.896 N/A THR 181.A OG1 ASP 183.A OD1 no hydrogen 2.550 N/A THR 181.A OG1 LYS 185.A O no hydrogen 3.329 N/A LEU 184.A N THR 181.A O no hydrogen 2.728 N/A LYS 185.A N ASP 183.A OD1 no hydrogen 3.144 N/A LYS 185.A NZ THR 181.A OG1 no hydrogen 2.926 N/A LYS 185.A NZ ASP 183.A OD1 no hydrogen 2.994 N/A LYS 185.A NZ ASP 183.A OD2 no hydrogen 2.647 N/A LEU 186.A N PHE 205.A O no hydrogen 3.092 N/A VAL 187.A N PHE 179.A O no hydrogen 2.887 N/A GLN 188.A N VAL 202.A O no hydrogen 2.757 N/A ARG 189.A N ILE 177.A O no hydrogen 2.931 N/A ARG 189.A NH1 LEU 151.A O no hydrogen 2.888 N/A ARG 189.A NH2 TYR 198.A O no hydrogen 2.775 N/A TYR 191.A N ILE 175.A O no hydrogen 2.837 N/A ASP 192.A N GLY 196.A O no hydrogen 3.161 N/A HIS 194.A N HIS 194.A ND1 no hydrogen 2.935 N/A LYS 195.A N ASP 192.A O no hydrogen 3.289 N/A TYR 198.A N ALA 190.A O no hydrogen 2.812 N/A TYR 198.A OH ASP 192.A OD2 no hydrogen 2.706 N/A VAL 202.A N GLN 188.A O no hydrogen 2.994 N/A ILE 204.A N LEU 186.A O no hydrogen 2.858 N/A PHE 205.A N LEU 186.A O no hydrogen 3.462 N/A ALA 208.A N LEU 184.A O no hydrogen 3.002 N/A ARG 211.A N GLN 180.A OE1 no hydrogen 3.047 N/A ARG 211.A NE PRO 156.A O no hydrogen 2.897 N/A THR 212.A N PRO 209.A O no hydrogen 3.094 N/A THR 212.A OG1 ALA 213.A O no hydrogen 3.429 N/A THR 212.A OG1 VAL 233.A O no hydrogen 2.502 N/A ALA 215.A N TYR 231.A O no hydrogen 2.907 N/A THR 217.A N ARG 229.A O no hydrogen 2.888 N/A THR 217.A OG1 SER 268.A OG no hydrogen 2.899 N/A SER 218.A OG THR 163.A OG1 no hydrogen 2.694 N/A PHE 219.A N TYR 227.A O no hydrogen 2.982 N/A GLY 222.A N SER 225.A O no hydrogen 2.808 N/A SER 224.A N ASP 169.A OD1 no hydrogen 2.903 N/A SER 224.A OG ASP 169.A OD2 no hydrogen 2.786 N/A SER 225.A OG ASN 223.A O no hydrogen 3.478 N/A TYR 227.A N PHE 219.A O no hydrogen 3.199 N/A MET 228.A N TRP 243.A O no hydrogen 3.008 N/A ARG 229.A N THR 217.A O no hydrogen 2.898 N/A ARG 229.A NH1 MET 228.A O no hydrogen 2.828 N/A ARG 229.A NH1 TRP 243.A O no hydrogen 2.984 N/A ARG 229.A NH1 ASP 244.A OD1 no hydrogen 3.211 N/A ARG 229.A NH2 ASP 244.A OD1 no hydrogen 2.999 N/A ILE 230.A N VAL 242.A O no hydrogen 2.929 N/A TYR 231.A N ALA 215.A O no hydrogen 2.614 N/A TYR 231.A OH GLN 241.A OE1 no hydrogen 2.615 N/A PHE 232.A N TRP 240.A O no hydrogen 3.099 N/A VAL 233.A N THR 212.A OG1 no hydrogen 3.017 N/A ASN 234.A N THR 238.A O no hydrogen 2.929 N/A SER 235.A N ASN 234.A OD1 no hydrogen 2.777 N/A SER 235.A OG ASN 234.A OD1 no hydrogen 3.529 N/A ASN 237.A N ASN 234.A O no hydrogen 2.977 N/A THR 238.A N ASP 236.A OD1 no hydrogen 3.000 N/A THR 238.A OG1 ASP 236.A OD1 no hydrogen 2.703 N/A THR 238.A OG1 ASP 236.A OD2 no hydrogen 3.213 N/A THR 238.A OG1 THR 254.A OG1 no hydrogen 2.784 N/A ILE 239.A N THR 256.A O no hydrogen 2.933 N/A TRP 240.A N PHE 232.A O no hydrogen 2.780 N/A TRP 240.A NE1 ASP 236.A OD2 no hydrogen 2.883 N/A GLN 241.A N GLY 253.A O no hydrogen 2.926 N/A VAL 242.A N ILE 230.A O no hydrogen 2.740 N/A TRP 243.A N MET 228.A O no hydrogen 2.921 N/A ASP 244.A N GLY 248.A O no hydrogen 3.055 N/A LYS 247.A N ASP 244.A O no hydrogen 2.883 N/A TYR 249.A OH GLN 188.A OE1 no hydrogen 2.486 N/A HIS 250.A NE2 ASP 244.A OD2 no hydrogen 2.515 N/A GLY 253.A N GLN 241.A O no hydrogen 3.153 N/A THR 254.A OG1 THR 238.A OG1 no hydrogen 2.784 N/A ILE 255.A N ILE 239.A O no hydrogen 2.688 N/A VAL 258.A N ASN 237.A O no hydrogen 3.006 N/A ILE 259.A N GLN 284.A O no hydrogen 2.884 N/A SER 262.A N ILE 259.A O no hydrogen 3.005 N/A SER 262.A OG GLU 263.A O no hydrogen 2.698 N/A SER 262.A OG GLN 284.A O no hydrogen 3.389 N/A ALA 265.A N TYR 282.A O no hydrogen 2.997 N/A ILE 267.A N ARG 280.A O no hydrogen 2.976 N/A SER 268.A OG THR 217.A OG1 no hydrogen 2.899 N/A SER 268.A OG SER 218.A O no hydrogen 3.398 N/A TRP 269.A N ASP 278.A O no hydrogen 2.933 N/A ASN 274.A N SER 271.A O no hydrogen 3.142 N/A ASN 274.A N SER 271.A OG no hydrogen 3.250 N/A GLY 276.A N SER 271.A O no hydrogen 2.738 N/A ASP 278.A N TRP 269.A O no hydrogen 2.803 N/A LEU 279.A N TRP 297.A O no hydrogen 2.898 N/A ARG 280.A N ILE 267.A O no hydrogen 3.025 N/A ARG 280.A NH1 ASP 278.A OD1 no hydrogen 2.958 N/A ARG 280.A NH1 LEU 279.A O no hydrogen 3.086 N/A ARG 280.A NH2 ASP 278.A OD1 no hydrogen 3.330 N/A LEU 281.A N TRP 295.A O no hydrogen 3.050 N/A TYR 282.A N ALA 265.A O no hydrogen 2.859 N/A TYR 282.A OH GLU 294.A OE2 no hydrogen 2.793 N/A PHE 283.A N SER 293.A O no hydrogen 3.284 N/A GLN 284.A N SER 262.A OG no hydrogen 2.901 N/A GLN 284.A NE2 LEU 9.A O no hydrogen 3.101 N/A GLN 284.A NE2 SER 290.A O no hydrogen 3.010 N/A THR 287.A N ASN 285.A OD1 no hydrogen 3.079 N/A THR 287.A OG1 ASN 285.A OD1 no hydrogen 2.702 N/A THR 287.A OG1 SER 293.A OG no hydrogen 3.250 N/A ILE 289.A N GLY 286.A O no hydrogen 3.134 N/A SER 290.A N TYR 288.A O no hydrogen 2.735 N/A SER 290.A OG ALA 5.A O no hydrogen 2.462 N/A ALA 291.A N THR 287.A O no hydrogen 2.959 N/A SER 293.A N PHE 283.A O no hydrogen 2.819 N/A SER 293.A OG ASN 285.A OD1 no hydrogen 3.331 N/A SER 293.A OG THR 287.A OG1 no hydrogen 3.250 N/A SER 293.A OG SER 308.A O no hydrogen 2.711 N/A GLU 294.A N ARG 307.A O no hydrogen 2.975 N/A TRP 295.A N LEU 281.A O no hydrogen 2.922 N/A TRP 295.A NE1 SER 303.A OG no hydrogen 2.940 N/A VAL 296.A N GLN 304.A O no hydrogen 2.803 N/A TRP 297.A N LEU 279.A O no hydrogen 3.004 N/A ASN 298.A N GLY 302.A O no hydrogen 3.464 N/A ARG 299.A NH1 PHE 272.A O no hydrogen 3.083 N/A ARG 299.A NH1 GLY 276.A O no hydrogen 2.918 N/A HIS 301.A N ASN 298.A OD1 no hydrogen 2.842 N/A GLY 302.A N ASN 298.A O no hydrogen 2.858 N/A GLN 304.A N VAL 296.A O no hydrogen 3.011 N/A GLN 304.A NE2 HIS 301.A O no hydrogen 3.220 N/A GLY 306.A N GLU 294.A O no hydrogen 2.908 N/A ARG 307.A N GLU 294.A OE1 no hydrogen 2.861 N/A ARG 307.A NE ALA 309.A O no hydrogen 3.060 N/A LEU 310.A N VAL 292.A O no hydrogen 2.780 N/A ALA 313.A N LEU 310.A O no hydrogen 3.022 N/A