Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4dfb_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 1.A N LYS 48.A O no hydrogen 2.431 N/A TYR 3.A OH PRO 47.A O no hydrogen 2.802 N/A THR 4.A N GLN 7.A OE1 no hydrogen 3.472 N/A GLN 7.A N THR 4.A OG1 no hydrogen 3.027 N/A VAL 8.A N THR 4.A O no hydrogen 3.067 N/A GLU 9.A N PHE 5.A O no hydrogen 2.977 N/A LYS 10.A N ASP 6.A O no hydrogen 3.106 N/A ALA 11.A N GLN 7.A O no hydrogen 2.921 N/A ILE 12.A N VAL 8.A O no hydrogen 3.166 N/A GLU 13.A N GLU 9.A O no hydrogen 3.032 N/A GLN 14.A N LYS 10.A O no hydrogen 3.099 N/A LEU 15.A N ILE 12.A O no hydrogen 3.179 N/A TYR 16.A N ILE 12.A O no hydrogen 2.603 N/A TYR 16.A OH THR 80.A O no hydrogen 3.389 N/A PHE 19.A N TYR 16.A O no hydrogen 3.275 N/A THR 20.A OG1 ASP 18.A O no hydrogen 3.534 N/A ASN 22.A N ASN 39.A OD1 no hydrogen 2.687 N/A THR 23.A N ASN 39.A OD1 no hydrogen 3.218 N/A GLU 25.A N GLU 37.A O no hydrogen 3.189 N/A SER 27.A N ALA 35.A O no hydrogen 2.719 N/A GLY 28.A N ALA 35.A O no hydrogen 3.255 N/A GLY 30.A N CYS 33.A O no hydrogen 2.947 N/A CYS 33.A SG GLY 52.A O no hydrogen 3.930 N/A ILE 34.A N PHE 46.A O no hydrogen 2.868 N/A ALA 35.A N GLY 28.A O no hydrogen 2.787 N/A TYR 36.A N PHE 44.A O no hydrogen 2.750 N/A TYR 36.A OH TYR 3.A O no hydrogen 3.290 N/A GLU 37.A N GLU 25.A O no hydrogen 2.890 N/A ILE 38.A N PHE 42.A O no hydrogen 2.893 N/A ASN 39.A N THR 23.A O no hydrogen 2.866 N/A ASN 39.A ND2 THR 20.A O no hydrogen 2.842 N/A ASP 41.A N ILE 38.A O no hydrogen 3.093 N/A PHE 42.A N ILE 38.A O no hydrogen 3.167 N/A ILE 43.A N PHE 92.A O no hydrogen 2.819 N/A PHE 44.A N TYR 36.A O no hydrogen 2.692 N/A LYS 45.A N ALA 90.A O no hydrogen 2.838 N/A LYS 45.A NZ GLU 59.A OE1 no hydrogen 3.169 N/A LYS 45.A NZ GLU 59.A OE2 no hydrogen 3.015 N/A LYS 45.A NZ ASP 213.A OD1 no hydrogen 3.030 N/A PHE 46.A N ILE 34.A O no hydrogen 2.996 N/A LYS 48.A N ASP 32.A O no hydrogen 2.822 N/A LYS 48.A NZ GLU 29.A OE2 no hydrogen 3.009 N/A LYS 48.A NZ GLY 30.A O no hydrogen 2.663 N/A HIS 49.A NE2 ASN 31.A O no hydrogen 2.825 N/A SER 50.A OG.A THR 85.A O no hydrogen 3.338 N/A SER 50.A OG.B THR 85.A O no hydrogen 2.681 N/A GLY 52.A N HIS 49.A ND1 no hydrogen 2.930 N/A SER 53.A N HIS 49.A O no hydrogen 3.076 N/A SER 53.A OG.B SER 50.A O no hydrogen 2.319 N/A THR 54.A N SER 50.A O no hydrogen 3.243 N/A THR 54.A N ARG 51.A O no hydrogen 3.151 N/A THR 54.A OG1 SER 50.A O no hydrogen 3.450 N/A ASN 55.A N ARG 51.A O no hydrogen 3.254 N/A ASN 55.A ND2 GLY 215.A O no hydrogen 2.874 N/A LEU 56.A N GLY 52.A O no hydrogen 2.877 N/A PHE 57.A N SER 53.A O no hydrogen 2.777 N/A ASN 58.A N THR 54.A O no hydrogen 2.961 N/A GLU 59.A N ASN 55.A O no hydrogen 2.912 N/A VAL 60.A N LEU 56.A O no hydrogen 3.044 N/A ASN 61.A N PHE 57.A O no hydrogen 3.091 N/A ILE 62.A N ASN 58.A O no hydrogen 2.820 N/A LEU 63.A N GLU 59.A O no hydrogen 2.838 N/A LYS 64.A N VAL 60.A O no hydrogen 3.095 N/A ARG 65.A N ASN 61.A O no hydrogen 3.404 N/A ARG 65.A N ILE 62.A O no hydrogen 3.260 N/A ARG 65.A NH1 GLY 134.A O no hydrogen 3.362 N/A ILE 66.A N ILE 62.A O no hydrogen 3.121 N/A GLU 76.A N THR 93.A OG1 no hydrogen 2.855 N/A VAL 78.A N GLY 91.A O no hydrogen 2.762 N/A PHE 79.A N GLY 91.A O no hydrogen 2.995 N/A THR 80.A N TYR 16.A OH no hydrogen 2.938 N/A GLY 81.A N PHE 89.A O no hydrogen 2.755 N/A SER 83.A N TYR 86.A O no hydrogen 2.673 N/A SER 83.A OG TYR 86.A O no hydrogen 3.564 N/A GLU 84.A N GLU 84.A OE1 no hydrogen 2.721 N/A THR 85.A N SER 83.A OG no hydrogen 3.098 N/A TYR 86.A N SER 83.A OG no hydrogen 2.815 N/A ALA 90.A N LYS 45.A O no hydrogen 3.170 N/A GLY 91.A N PHE 79.A O no hydrogen 2.673 N/A PHE 92.A N ILE 43.A O no hydrogen 2.922 N/A THR 93.A N GLU 76.A O no hydrogen 2.965 N/A LYS 94.A N ASP 41.A O no hydrogen 2.883 N/A LYS 94.A NZ GLU 37.A OE2 no hydrogen 2.724 N/A VAL 98.A N PHE 201.A O no hydrogen 3.110 N/A LEU 100.A N ILE 199.A O no hydrogen 2.689 N/A THR 101.A N PRO 99.A O no hydrogen 2.832 N/A LEU 104.A N THR 101.A OG1 no hydrogen 3.141 N/A LEU 105.A N THR 101.A O no hydrogen 2.856 N/A ASN 106.A N PRO 102.A O no hydrogen 3.190 N/A ASN 106.A ND2 PRO 102.A O no hydrogen 3.026 N/A ASN 107.A N LEU 104.A O no hydrogen 3.283 N/A LEU 108.A N LEU 105.A O no hydrogen 3.285 N/A SER 112.A N PRO 109.A O no hydrogen 2.979 N/A GLN 113.A N PRO 109.A O no hydrogen 3.053 N/A GLN 113.A NE2 LEU 108.A O no hydrogen 2.543 N/A ASN 114.A N LYS 110.A O no hydrogen 2.889 N/A GLN 115.A N GLN 111.A O no hydrogen 3.054 N/A ALA 116.A N SER 112.A O no hydrogen 2.970 N/A ALA 117.A N GLN 113.A O no hydrogen 3.055 N/A LYS 118.A N ASN 114.A O no hydrogen 2.999 N/A ASP 119.A N GLN 115.A O no hydrogen 2.825 N/A LEU 120.A N ALA 116.A O no hydrogen 2.952 N/A ALA 121.A N ALA 117.A O no hydrogen 3.073 N/A ARG 122.A N.A LYS 118.A O no hydrogen 2.963 N/A ARG 122.A N.B LYS 118.A O no hydrogen 2.964 N/A ARG 122.A NH2.B ASP 119.A OD1 no hydrogen 3.376 N/A PHE 123.A N ASP 119.A O no hydrogen 2.983 N/A LEU 124.A N LEU 120.A O no hydrogen 2.995 N/A SER 125.A N ALA 121.A O no hydrogen 2.920 N/A SER 125.A OG ALA 121.A O no hydrogen 2.668 N/A GLU 126.A N ARG 122.A O.A no hydrogen 3.167 N/A GLU 126.A N ARG 122.A O.B no hydrogen 3.097 N/A LEU 127.A N PHE 123.A O no hydrogen 2.850 N/A HIS 128.A N LEU 124.A O no hydrogen 2.822 N/A HIS 128.A ND1 TYR 244.A OH no hydrogen 2.935 N/A HIS 128.A NE2 ASP 225.A OD2 no hydrogen 2.743 N/A SER 129.A N GLU 126.A O no hydrogen 3.143 N/A SER 129.A OG SER 125.A O no hydrogen 2.556 N/A ILE 130.A N LEU 127.A O no hydrogen 3.338 N/A SER 133.A N ASN 131.A OD1 no hydrogen 3.301 N/A SER 133.A OG ASN 131.A OD1 no hydrogen 2.309 N/A PHE 135.A N ILE 132.A O no hydrogen 3.324 N/A LEU 139.A N LYS 136.A O no hydrogen 2.725 N/A VAL 140.A N SER 137.A O no hydrogen 3.178 N/A LEU 141.A N ILE 219.A O no hydrogen 2.827 N/A PHE 143.A N TYR 185.A OH no hydrogen 2.989 N/A ARG 144.A NH1 LEU 177.A O no hydrogen 3.052 N/A GLU 145.A N ASP 142.A OD1 no hydrogen 3.078 N/A LYS 146.A N ASP 142.A O no hydrogen 2.895 N/A LYS 146.A NZ ASP 150.A OD2 no hydrogen 2.500 N/A LYS 146.A NZ GLU 265.A OE2 no hydrogen 3.212 N/A ILE 147.A N PHE 143.A O no hydrogen 2.888 N/A ASN 148.A N ARG 144.A O no hydrogen 3.024 N/A GLU 149.A N GLU 145.A O no hydrogen 2.826 N/A ASP 150.A N LYS 146.A O no hydrogen 2.954 N/A ASN 151.A N ILE 147.A O no hydrogen 2.957 N/A LYS 152.A N ASN 148.A O no hydrogen 3.234 N/A LYS 153.A N GLU 149.A O no hydrogen 3.075 N/A LYS 153.A NZ GLU 272.A OE2 no hydrogen 2.933 N/A ILE 154.A N ASP 150.A O no hydrogen 2.723 N/A LYS 155.A N ASN 151.A O no hydrogen 2.948 N/A LYS 155.A NZ ASP 170.A OD1 no hydrogen 2.988 N/A LYS 155.A NZ ASP 170.A OD2 no hydrogen 3.436 N/A LYS 156.A N LYS 152.A O no hydrogen 3.070 N/A LEU 157.A N LYS 153.A O no hydrogen 2.851 N/A LEU 158.A N ILE 154.A O no hydrogen 2.773 N/A ARG 160.A NE SER 159.A OG no hydrogen 3.346 N/A GLU 161.A N LEU 158.A O no hydrogen 3.147 N/A LEU 162.A N LEU 158.A O no hydrogen 3.206 N/A LYS 163.A N GLN 166.A OE1 no hydrogen 3.010 N/A LYS 167.A NZ ASP 171.A OD2 no hydrogen 2.887 N/A LYS 168.A N PRO 165.A O no hydrogen 3.247 N/A LYS 168.A NZ ILE 288.A O no hydrogen 2.713 N/A VAL 169.A N GLN 166.A O no hydrogen 3.452 N/A ASP 171.A N LYS 167.A O no hydrogen 2.846 N/A PHE 172.A N LYS 168.A O no hydrogen 2.777 N/A TYR 173.A N VAL 169.A O no hydrogen 3.014 N/A TYR 173.A OH TYR 261.A OH no hydrogen 3.006 N/A ARG 174.A N ASP 170.A O no hydrogen 2.921 N/A ARG 174.A NH2 ASP 171.A OD1 no hydrogen 2.361 N/A ASP 175.A N ASP 171.A O no hydrogen 2.916 N/A ILE 176.A N PHE 172.A O no hydrogen 3.183 N/A LEU 177.A N TYR 173.A O no hydrogen 3.163 N/A GLU 178.A N ARG 174.A O no hydrogen 2.898 N/A ASN 179.A N ILE 176.A O no hydrogen 3.067 N/A ASN 179.A ND2 GLU 254.A OE2 no hydrogen 2.946 N/A ILE 181.A N ASN 179.A OD1 no hydrogen 3.393 N/A TYR 182.A N ASN 179.A O no hydrogen 3.467 N/A PHE 183.A N GLU 180.A O no hydrogen 3.304 N/A CYS 188.A N SER 220.A O no hydrogen 3.048 N/A CYS 188.A SG.A HIS 128.A O no hydrogen 3.294 N/A CYS 188.A SG.A TYR 186.A O no hydrogen 3.191 N/A CYS 188.A SG.B LEU 189.A O no hydrogen 3.977 N/A ILE 190.A N ALA 218.A O no hydrogen 2.811 N/A HIS 191.A N ASP 225.A OD2 no hydrogen 3.109 N/A HIS 191.A NE2 ILE 212.A O no hydrogen 2.808 N/A ASN 192.A N ASP 225.A OD1 no hydrogen 2.883 N/A ASN 192.A ND2 ASP 216.A O no hydrogen 3.076 N/A ASP 193.A N HIS 191.A ND1 no hydrogen 3.179 N/A SER 196.A N GLU 232.A OE1 no hydrogen 2.869 N/A SER 196.A OG GLU 232.A OE1 no hydrogen 2.778 N/A HIS 198.A N SER 195.A O no hydrogen 3.040 N/A HIS 198.A ND1 ASP 193.A O no hydrogen 2.701 N/A ILE 199.A N SER 196.A O no hydrogen 3.343 N/A LEU 200.A N GLY 210.A O no hydrogen 2.839 N/A PHE 201.A N VAL 98.A O no hydrogen 2.563 N/A ASP 202.A N THR 207.A O no hydrogen 2.802 N/A GLU 204.A N ASP 202.A OD1 no hydrogen 3.105 N/A LYS 205.A NZ ASP 202.A OD2 no hydrogen 2.701 N/A THR 207.A N ASP 202.A O no hydrogen 3.218 N/A CYS 209.A N LEU 200.A O no hydrogen 2.913 N/A CYS 209.A SG LYS 96.A O no hydrogen 3.145 N/A ILE 211.A N PRO 73.A O no hydrogen 2.955 N/A ILE 212.A N HIS 198.A O no hydrogen 3.017 N/A PHE 214.A N GLU 59.A OE2 no hydrogen 3.094 N/A ALA 217.A N PHE 214.A O no hydrogen 3.304 N/A ALA 218.A N ILE 190.A O no hydrogen 3.223 N/A ILE 219.A N LEU 139.A O no hydrogen 2.668 N/A SER 220.A N CYS 188.A O no hydrogen 2.865 N/A SER 220.A OG LEU 141.A O no hydrogen 3.076 N/A ASP 223.A N ASP 221.A OD1 no hydrogen 3.097 N/A ASN 224.A N ASP 221.A O no hydrogen 3.002 N/A ASN 224.A ND2 ASN 192.A OD1 no hydrogen 3.465 N/A ASP 225.A N PRO 222.A O no hydrogen 3.214 N/A PHE 226.A N ASP 223.A O no hydrogen 3.088 N/A ILE 227.A N ASP 223.A O no hydrogen 3.062 N/A SER 228.A N ASN 224.A O no hydrogen 3.208 N/A SER 228.A OG PHE 194.A O no hydrogen 2.701 N/A SER 228.A OG ASN 224.A O no hydrogen 3.107 N/A LEU 229.A N PHE 226.A O no hydrogen 3.037 N/A TYR 233.A N LEU 229.A O no hydrogen 3.013 N/A TYR 233.A OH LEU 100.A O no hydrogen 2.508 N/A PHE 236.A N GLY 234.A O no hydrogen 3.251 N/A VAL 237.A N GLY 234.A O no hydrogen 3.277 N/A ILE 240.A N PHE 236.A O no hydrogen 3.212 N/A LEU 241.A N VAL 237.A O no hydrogen 2.774 N/A ASN 242.A N SER 238.A O no hydrogen 2.977 N/A ASN 242.A ND2 SER 238.A O no hydrogen 2.605 N/A HIS 243.A N LYS 239.A O no hydrogen 2.991 N/A TYR 244.A N ILE 240.A O no hydrogen 2.807 N/A TYR 244.A OH HIS 128.A ND1 no hydrogen 2.935 N/A LYS 245.A N ASN 242.A O no hydrogen 3.164 N/A HIS 246.A N LEU 241.A O no hydrogen 2.884 N/A HIS 246.A NE2 ASP 223.A OD1 no hydrogen 2.774 N/A LYS 247.A NZ LYS 245.A O no hydrogen 2.908 N/A ASP 248.A N HIS 246.A ND1 no hydrogen 2.957 N/A THR 251.A OG1 ASP 248.A OD2 no hydrogen 2.432 N/A LEU 253.A N ILE 249.A O no hydrogen 3.012 N/A GLU 254.A N PRO 250.A O no hydrogen 2.870 N/A LYS 255.A N THR 251.A O no hydrogen 2.742 N/A LYS 255.A NZ ASP 221.A OD1 no hydrogen 3.435 N/A LYS 255.A NZ ASP 221.A OD2 no hydrogen 2.630 N/A LYS 255.A NZ ASP 223.A OD2 no hydrogen 2.783 N/A TYR 256.A N VAL 252.A O no hydrogen 2.901 N/A ARG 257.A N LEU 253.A O no hydrogen 2.996 N/A GLU 259.A N TYR 256.A O no hydrogen 3.103 N/A LYS 260.A N ARG 257.A O no hydrogen 3.245 N/A TYR 261.A OH ASP 150.A OD2 no hydrogen 2.865 N/A TYR 261.A OH TYR 173.A OH no hydrogen 3.006 N/A SER 263.A OG GLU 284.A OE1 no hydrogen 2.576 N/A PHE 264.A N TYR 261.A O no hydrogen 3.034 N/A GLU 265.A N TYR 261.A O no hydrogen 3.259 N/A LYS 266.A N TRP 262.A O no hydrogen 3.019 N/A LYS 266.A NZ GLU 280.A OE1 no hydrogen 2.927 N/A LYS 266.A NZ GLU 284.A OE1 no hydrogen 3.534 N/A LYS 266.A NZ GLU 284.A OE2 no hydrogen 2.549 N/A ILE 268.A N PHE 264.A O no hydrogen 3.192 N/A TYR 269.A N GLU 265.A O no hydrogen 2.845 N/A GLY 270.A N LYS 266.A O no hydrogen 2.896 N/A LYS 271.A N ILE 267.A O no hydrogen 3.148 N/A LYS 271.A N ILE 268.A O no hydrogen 3.225 N/A GLU 272.A N ILE 268.A O no hydrogen 2.831 N/A TYR 273.A N TYR 269.A O no hydrogen 2.702 N/A TYR 273.A OH ASP 32.A OD1 no hydrogen 2.657 N/A TYR 275.A OH ASN 31.A OD1 no hydrogen 3.086 N/A TYR 278.A N TYR 275.A O no hydrogen 3.030 N/A TYR 278.A OH GLU 161.A OE2 no hydrogen 2.690 N/A GLU 280.A N ASP 276.A O no hydrogen 2.992 N/A GLY 281.A N TRP 277.A O no hydrogen 2.915 N/A LEU 282.A N TYR 278.A O no hydrogen 2.873 N/A ASN 283.A N GLU 279.A O no hydrogen 3.010 N/A GLU 284.A N GLU 280.A O no hydrogen 3.038 N/A ILE 285.A N GLY 281.A O no hydrogen 3.035 N/A ARG 286.A N LEU 282.A O no hydrogen 3.268 N/A ARG 286.A NH2 GLU 161.A O no hydrogen 3.023 N/A SER 287.A OG ASN 283.A O no hydrogen 3.475 N/A SER 287.A OG GLU 284.A O no hydrogen 2.629 N/A