Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4dje_C.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 6.A N THR 3.A OG1 no hydrogen 2.874 N/A ILE 7.A N THR 3.A O no hydrogen 3.145 N/A TYR 8.A N GLY 4.A O no hydrogen 3.038 N/A LYS 9.A N LEU 5.A O no hydrogen 2.803 N/A GLN 10.A N TYR 8.A O no hydrogen 2.624 N/A GLN 10.A NE2 LYS 9.A O no hydrogen 2.782 N/A LEU 11.A N TYR 8.A O no hydrogen 3.026 N/A LYS 14.A NZ PRO 12.A O no hydrogen 3.463 N/A CYS 19.A SG THR 21.A O no hydrogen 3.438 N/A GLY 20.A N GLY 17.A O no hydrogen 3.134 N/A ALA 26.A N THR 23.A OG1 no hydrogen 3.220 N/A PHE 27.A N THR 23.A O no hydrogen 3.169 N/A ALA 28.A N CYS 24.A O no hydrogen 2.695 N/A MET 29.A N LEU 25.A O no hydrogen 3.396 N/A ASN 30.A N ALA 26.A O no hydrogen 3.216 N/A LEU 31.A N PHE 27.A O no hydrogen 3.004 N/A ALA 32.A N ALA 28.A O no hydrogen 3.231 N/A SER 33.A N MET 29.A O no hydrogen 3.106 N/A GLY 34.A N LEU 31.A O no hydrogen 3.180 N/A LYS 35.A N ASN 30.A O no hydrogen 2.504 N/A SER 40.A N SER 37.A O no hydrogen 3.415 N/A ALA 48.A N SER 45.A O no hydrogen 3.152 N/A ARG 49.A N SER 45.A O no hydrogen 3.370 N/A GLU 50.A N ASP 46.A O no hydrogen 2.990 N/A ALA 51.A N ALA 47.A O no hydrogen 3.138 N/A LEU 52.A N ALA 48.A O no hydrogen 3.252 N/A ASP 53.A N ARG 49.A O no hydrogen 3.135 N/A ALA 54.A N GLU 50.A O no hydrogen 2.993 N/A ALA 54.A N ALA 51.A O no hydrogen 3.036 N/A ALA 55.A N ALA 51.A O no hydrogen 2.638 N/A ALA 61.A N GLY 260.A O no hydrogen 2.846 N/A VAL 63.A N MET 74.A O no hydrogen 3.402 N/A LEU 65.A N VAL 72.A O no hydrogen 2.880 N/A GLY 66.A N VAL 64.A O no hydrogen 3.145 N/A ALA 71.A N GLY 68.A O no hydrogen 3.102 N/A MET 74.A N VAL 63.A O no hydrogen 3.265 N/A ASP 76.A N ALA 61.A O no hydrogen 3.314 N/A ARG 82.A NE LEU 310.A O no hydrogen 3.158 N/A ASP 84.A N PHE 81.A O no hydrogen 3.398 N/A TYR 88.A N GLU 77.A OE2 no hydrogen 2.879 N/A THR 91.A OG1 ALA 287.A O no hydrogen 3.212 N/A THR 91.A OG1 TYR 311.A OH no hydrogen 2.999 N/A ALA 92.A N SER 288.A O no hydrogen 2.508 N/A ILE 93.A N GLN 128.A OE1 no hydrogen 2.671 N/A ALA 94.A N VAL 290.A O no hydrogen 3.086 N/A ILE 95.A N ALA 129.A O no hydrogen 3.348 N/A GLN 96.A N LEU 292.A O no hydrogen 2.893 N/A VAL 97.A N ALA 131.A O no hydrogen 2.775 N/A SER 103.A OG GLU 104.A OE1 no hydrogen 2.907 N/A GLU 104.A N GLU 104.A OE1 no hydrogen 2.679 N/A LEU 106.A N SER 102.A O no hydrogen 2.885 N/A LYS 107.A N SER 103.A O no hydrogen 2.980 N/A ALA 108.A N GLU 104.A O no hydrogen 3.286 N/A LYS 109.A N GLU 105.A O no hydrogen 3.132 N/A LYS 109.A NZ GLN 96.A O no hydrogen 3.462 N/A VAL 110.A N LEU 106.A O no hydrogen 2.914 N/A GLU 111.A N LYS 107.A O no hydrogen 2.934 N/A ALA 112.A N ALA 108.A O no hydrogen 3.338 N/A ILE 113.A N LYS 109.A O no hydrogen 3.042 N/A ASN 114.A N VAL 110.A O no hydrogen 3.103 N/A ASN 114.A ND2 THR 153.A OG1 no hydrogen 2.828 N/A GLY 115.A N ALA 112.A O no hydrogen 3.294 N/A LEU 116.A N ILE 113.A O no hydrogen 3.200 N/A PHE 118.A N TYR 125.A O no hydrogen 2.959 N/A ARG 120.A N GLN 123.A O no hydrogen 3.159 N/A ARG 120.A NE TYR 125.A OH no hydrogen 3.219 N/A ARG 120.A NH2 TYR 125.A OH no hydrogen 2.576 N/A GLN 123.A N ARG 120.A O no hydrogen 2.553 N/A HIS 124.A ND1 ASP 119.A OD1 no hydrogen 2.460 N/A TYR 125.A N PHE 118.A O no hydrogen 3.034 N/A GLN 128.A N ILE 93.A O no hydrogen 3.038 N/A GLN 128.A NE2 THR 126.A O no hydrogen 3.343 N/A ALA 129.A N ILE 93.A O no hydrogen 3.082 N/A ILE 130.A N ASN 156.A O no hydrogen 3.166 N/A ALA 131.A N ILE 95.A O no hydrogen 2.755 N/A ILE 132.A N VAL 158.A O no hydrogen 3.068 N/A ARG 133.A N VAL 97.A O no hydrogen 3.419 N/A ARG 133.A NE GLN 96.A OE1 no hydrogen 2.671 N/A HIS 134.A N MET 160.A O no hydrogen 3.041 N/A ASP 135.A N ASP 99.A OD1 no hydrogen 2.624 N/A ALA 136.A N ASP 99.A OD1 no hydrogen 3.214 N/A ASP 138.A N ASP 138.A OD1 no hydrogen 2.552 N/A ALA 141.A N ASP 138.A O no hydrogen 3.111 N/A LYS 143.A NZ GLU 169.A OE2 no hydrogen 3.389 N/A ALA 144.A N ALA 140.A O no hydrogen 3.347 N/A ALA 145.A N PHE 142.A O no hydrogen 3.258 N/A VAL 146.A N PHE 142.A O no hydrogen 3.179 N/A ALA 147.A N LYS 143.A O no hydrogen 3.438 N/A VAL 149.A N ALA 145.A O no hydrogen 2.981 N/A ALA 150.A N VAL 146.A O no hydrogen 2.911 N/A ALA 152.A N VAL 149.A O no hydrogen 3.127 N/A THR 153.A N VAL 149.A O no hydrogen 3.076 N/A LEU 155.A N THR 153.A OG1 no hydrogen 3.131 N/A ASN 156.A N GLN 128.A O no hydrogen 3.133 N/A ASN 156.A ND2 THR 70.A O no hydrogen 3.073 N/A ASN 156.A ND2 GLN 128.A O no hydrogen 3.017 N/A VAL 158.A N ILE 130.A O no hydrogen 3.159 N/A LEU 159.A N LEU 180.A O no hydrogen 2.865 N/A MET 160.A N ILE 132.A O no hydrogen 2.901 N/A ALA 161.A N TYR 182.A O no hydrogen 2.953 N/A LEU 167.A N ASP 163.A O no hydrogen 3.119 N/A LYS 168.A N PRO 164.A O no hydrogen 2.810 N/A GLU 169.A N ASP 165.A O no hydrogen 3.321 N/A ALA 170.A N LEU 167.A O no hydrogen 2.947 N/A LEU 171.A N LEU 167.A O no hydrogen 2.646 N/A ALA 172.A N LYS 168.A O no hydrogen 2.896 N/A VAL 174.A N LEU 171.A O no hydrogen 3.113 N/A ARG 177.A N VAL 174.A O no hydrogen 3.197 N/A ARG 177.A NH1 ALA 150.A O no hydrogen 3.543 N/A LYS 178.A NZ ALA 67.A O no hydrogen 3.121 N/A LEU 180.A N LEU 157.A O no hydrogen 3.125 N/A LEU 181.A N PRO 202.A O no hydrogen 3.116 N/A TYR 182.A N LEU 159.A O no hydrogen 2.888 N/A TYR 182.A OH ASP 231.A OD2 no hydrogen 2.912 N/A ALA 184.A N ALA 204.A O no hydrogen 2.627 N/A THR 185.A OG1 ALA 183.A O no hydrogen 3.530 N/A ASN 188.A N THR 185.A O no hydrogen 2.997 N/A MET 192.A N ASN 188.A O no hydrogen 3.442 N/A THR 193.A N TYR 189.A O no hydrogen 2.990 N/A THR 193.A OG1 TYR 189.A O no hydrogen 2.364 N/A LEU 195.A N ALA 191.A O no hydrogen 3.285 N/A ALA 196.A N MET 192.A O no hydrogen 3.393 N/A LYS 197.A N ALA 194.A O no hydrogen 3.227 N/A LYS 197.A NZ LEU 223.A O no hydrogen 2.928 N/A GLU 198.A N ALA 194.A O no hydrogen 3.219 N/A ASN 199.A N LEU 195.A O no hydrogen 3.326 N/A CYS 201.A N ALA 196.A O no hydrogen 3.242 N/A CYS 201.A SG ALA 175.A O no hydrogen 3.814 N/A CYS 201.A SG LYS 178.A O no hydrogen 3.740 N/A CYS 201.A SG ASN 199.A O no hydrogen 3.369 N/A LEU 203.A N GLN 227.A O no hydrogen 3.213 N/A ALA 204.A N LEU 181.A O no hydrogen 2.722 N/A VAL 205.A N VAL 229.A O no hydrogen 2.774 N/A TYR 206.A N ALA 184.A O no hydrogen 3.068 N/A GLY 207.A N ASP 231.A O no hydrogen 3.064 N/A GLY 209.A N PRO 232.A O no hydrogen 3.247 N/A ALA 214.A N GLU 211.A O no hydrogen 3.028 N/A GLU 215.A N GLU 211.A O no hydrogen 3.216 N/A LEU 216.A N GLU 212.A O no hydrogen 3.325 N/A VAL 217.A N LEU 213.A O no hydrogen 3.220 N/A ASP 218.A N ALA 214.A O no hydrogen 3.390 N/A ILE 220.A N LEU 216.A O no hydrogen 3.183 N/A VAL 221.A N VAL 217.A O no hydrogen 2.912 N/A ALA 222.A N ASP 218.A O no hydrogen 3.260 N/A LEU 223.A N ILE 220.A O no hydrogen 3.150 N/A GLY 224.A N VAL 221.A O no hydrogen 3.143 N/A VAL 229.A N LEU 203.A O no hydrogen 3.061 N/A LEU 230.A N PRO 262.A O no hydrogen 2.901 N/A ASP 231.A N VAL 205.A O no hydrogen 2.740 N/A GLY 233.A N ASP 231.A OD1 no hydrogen 3.002 N/A ARG 235.A NH2 ASP 231.A OD1 no hydrogen 3.092 N/A ARG 239.A NE ARG 239.A O no hydrogen 2.943 N/A ILE 241.A N THR 237.A O no hydrogen 3.136 N/A PHE 244.A N ALA 240.A O no hydrogen 2.669 N/A THR 245.A N ILE 241.A O no hydrogen 3.163 N/A THR 245.A OG1 ILE 241.A O no hydrogen 2.495 N/A GLN 246.A N ALA 242.A O no hydrogen 3.312 N/A ILE 247.A N ASP 243.A O no hydrogen 3.395 N/A ARG 248.A N PHE 244.A O no hydrogen 3.472 N/A ARG 248.A NE GLU 79.A O no hydrogen 3.267 N/A ARG 249.A N THR 245.A O no hydrogen 2.744 N/A LEU 250.A N GLN 246.A O no hydrogen 2.645 N/A ALA 251.A N ILE 247.A O no hydrogen 3.416 N/A ILE 252.A N ARG 249.A O no hydrogen 3.146 N/A LYS 253.A N ARG 249.A O no hydrogen 2.692 N/A LYS 254.A N LEU 250.A O no hydrogen 3.188 N/A ARG 255.A NE ALA 54.A O no hydrogen 3.583 N/A PHE 256.A N LEU 250.A O no hydrogen 2.678 N/A ARG 257.A NH1 PRO 58.A O no hydrogen 2.942 N/A ARG 257.A NH2 ALA 54.A O no hydrogen 2.970 N/A SER 258.A OG ASP 218.A OD1 no hydrogen 2.441 N/A SER 258.A OG ASP 218.A OD2 no hydrogen 3.335 N/A PHE 259.A N PHE 256.A O no hydrogen 3.296 N/A ILE 264.A N LEU 230.A O no hydrogen 2.865 N/A ALA 265.A N LEU 289.A O no hydrogen 2.654 N/A THR 267.A OG1 GLU 275.A OE2 no hydrogen 2.861 N/A THR 267.A OG1 VAL 291.A O no hydrogen 3.074 N/A THR 268.A N GLN 278.A OE1 no hydrogen 3.349 N/A THR 268.A OG1 ARG 235.A O no hydrogen 2.502 N/A ALA 269.A N GLN 278.A OE1 no hydrogen 3.182 N/A LEU 273.A N ASN 271.A OD1 no hydrogen 2.871 N/A GLU 275.A N ASN 271.A O no hydrogen 2.879 N/A VAL 276.A N PRO 272.A O no hydrogen 3.398 N/A LEU 277.A N LEU 273.A O no hydrogen 3.439 N/A GLN 278.A N ASP 274.A O no hydrogen 3.094 N/A ALA 279.A N GLU 275.A O no hydrogen 2.935 N/A ALA 279.A N VAL 276.A O no hydrogen 2.916 N/A VAL 280.A N VAL 276.A O no hydrogen 2.859 N/A ASN 281.A N LEU 277.A O no hydrogen 3.408 N/A VAL 283.A N ALA 279.A O no hydrogen 3.027 N/A THR 284.A N VAL 280.A O no hydrogen 3.276 N/A THR 284.A OG1 VAL 280.A O no hydrogen 2.614 N/A LYS 285.A N ASN 281.A O no hydrogen 2.880 N/A TYR 286.A OH LEU 80.A O no hydrogen 2.568 N/A ALA 287.A N TYR 282.A O no hydrogen 3.204 N/A SER 288.A N ILE 263.A O no hydrogen 3.081 N/A LEU 289.A N ILE 263.A O no hydrogen 3.001 N/A VAL 290.A N ALA 92.A O no hydrogen 2.996 N/A VAL 291.A N ALA 265.A O no hydrogen 2.963 N/A LEU 292.A N ALA 94.A O no hydrogen 2.738 N/A ARG 293.A N GLU 275.A OE2 no hydrogen 2.503 N/A ARG 293.A NH1 THR 267.A O no hydrogen 3.442 N/A THR 294.A OG1 HIS 299.A ND1 no hydrogen 2.671 N/A GLU 298.A N GLU 298.A OE1 no hydrogen 2.449 N/A HIS 299.A N ALA 296.A O no hydrogen 3.135 N/A HIS 299.A ND1 THR 294.A OG1 no hydrogen 2.671 N/A LEU 300.A N ALA 296.A O no hydrogen 3.199 N/A LEU 304.A N LEU 300.A O no hydrogen 2.841 N/A SER 305.A N LEU 301.A O no hydrogen 2.967 N/A SER 305.A OG LEU 301.A O no hydrogen 2.434 N/A TRP 306.A N PRO 302.A O no hydrogen 3.314 N/A TRP 306.A NE1 THR 284.A OG1 no hydrogen 2.755 N/A ARG 307.A N LEU 303.A O no hydrogen 3.252 N/A ARG 307.A NH1 THR 91.A O no hydrogen 3.203 N/A ARG 307.A NH1 THR 126.A O no hydrogen 3.403 N/A ARG 307.A NH1 GLN 128.A OE1 no hydrogen 3.034 N/A ARG 307.A NH2 THR 126.A O no hydrogen 2.945 N/A GLN 308.A N LEU 304.A O no hydrogen 3.328 N/A ASN 309.A N SER 305.A O no hydrogen 3.152 N/A LEU 310.A N TRP 306.A O no hydrogen 3.084 N/A TYR 311.A OH THR 91.A OG1 no hydrogen 2.999 N/A THR 312.A OG1 ASN 309.A O no hydrogen 2.517 N/A VAL 316.A N ASP 313.A OD2 no hydrogen 3.396 N/A ARG 319.A NE ASP 368.A O no hydrogen 2.638 N/A VAL 320.A N ASN 341.A O no hydrogen 2.750 N/A ASN 325.A N LEU 362.A O no hydrogen 2.972 N/A ILE 327.A N SER 360.A O no hydrogen 2.810 N/A ASN 331.A N ASN 331.A OD1 no hydrogen 2.608 N/A ASN 333.A N ASN 331.A OD1 no hydrogen 3.411 N/A SER 334.A OG ASN 331.A OD1 no hydrogen 2.600 N/A SER 334.A OG PRO 359.A O no hydrogen 3.103 N/A TYR 337.A N TYR 361.A O no hydrogen 3.245 N/A VAL 338.A N ILE 405.A O no hydrogen 3.150 N/A THR 339.A N LEU 363.A O no hydrogen 3.014 N/A THR 340.A N THR 339.A OG1 no hydrogen 2.879 N/A THR 340.A OG1 LEU 370.A O no hydrogen 3.398 N/A SER 343.A N ILE 318.A O no hydrogen 2.536 N/A THR 345.A N PHE 342.A O no hydrogen 3.081 N/A THR 345.A OG1 SER 371.A OG no hydrogen 2.706 N/A TYR 346.A N PHE 342.A O no hydrogen 3.020 N/A SER 348.A N THR 345.A O no hydrogen 3.082 N/A VAL 349.A N TYR 346.A O no hydrogen 2.931 N/A GLU 350.A N TYR 346.A O no hydrogen 2.875 N/A ILE 353.A N VAL 349.A O no hydrogen 2.689 N/A GLU 354.A N GLU 350.A O no hydrogen 3.031 N/A SER 355.A N GLY 351.A O no hydrogen 3.168 N/A LYS 357.A N ILE 353.A O no hydrogen 3.350 N/A SER 360.A N ILE 327.A O no hydrogen 2.752 N/A SER 360.A OG PRO 335.A O no hydrogen 3.164 N/A TYR 361.A N PRO 335.A O no hydrogen 3.304 N/A LEU 362.A N ASN 325.A O no hydrogen 2.852 N/A LEU 363.A N TYR 337.A O no hydrogen 2.788 N/A SER 364.A OG GLU 321.A O no hydrogen 2.726 N/A SER 364.A OG LYS 323.A O no hydrogen 3.057 N/A VAL 365.A N THR 339.A O no hydrogen 2.909 N/A THR 367.A OG1 ASN 341.A OD1 no hydrogen 3.423 N/A THR 367.A OG1 LEU 370.A O no hydrogen 2.737 N/A ASP 368.A N ASN 341.A OD1 no hydrogen 3.083 N/A ASP 368.A N ASP 366.A OD1 no hydrogen 2.980 N/A SER 371.A OG THR 345.A OG1 no hydrogen 2.706 N/A ALA 375.A N SER 371.A O no hydrogen 2.524 N/A TYR 376.A N VAL 372.A O no hydrogen 3.057 N/A ALA 377.A N LEU 373.A O no hydrogen 3.014 N/A ASP 378.A N THR 374.A O no hydrogen 2.961 N/A GLY 379.A N TYR 376.A O no hydrogen 3.159 N/A ILE 386.A N GLU 382.A O no hydrogen 3.365 N/A ALA 387.A N ALA 383.A O no hydrogen 3.226 N/A ALA 388.A N GLU 384.A O no hydrogen 3.200 N/A VAL 389.A N LYS 385.A O no hydrogen 3.242 N/A MET 390.A N ILE 386.A O no hydrogen 2.993 N/A LYS 391.A NZ LEU 420.A O no hydrogen 3.171 N/A LYS 392.A N VAL 389.A O no hydrogen 3.132 N/A VAL 399.A N LEU 395.A O no hydrogen 3.358 N/A LYS 400.A N GLU 332.A O no hydrogen 3.017 N/A ILE 404.A N GLU 424.A O no hydrogen 3.275 N/A ILE 405.A N VAL 336.A O no hydrogen 2.507 N/A ILE 406.A N ILE 426.A O no hydrogen 2.909 N/A GLY 408.A N PRO 429.A O no hydrogen 2.738 N/A LEU 413.A N VAL 410.A O no hydrogen 3.025 N/A LYS 414.A N ALA 411.A O no hydrogen 2.749 N/A LEU 417.A N LEU 413.A O no hydrogen 3.199 N/A GLU 418.A N LYS 414.A O no hydrogen 3.152 N/A GLU 418.A N GLY 415.A O no hydrogen 3.122 N/A LEU 420.A N LYS 416.A O no hydrogen 3.484 N/A THR 421.A N LEU 417.A O no hydrogen 3.280 N/A ILE 426.A N ILE 404.A O no hydrogen 3.207 N/A GLY 428.A N ILE 406.A O no hydrogen 2.661 N/A GLY 434.A N GLU 431.A O no hydrogen 3.093 N/A ILE 435.A N ALA 432.A O no hydrogen 2.828 N/A ALA 437.A N GLY 434.A O no hydrogen 3.009 N/A PHE 438.A N GLY 434.A O no hydrogen 3.115 N/A ALA 441.A N PHE 438.A O no hydrogen 2.974 N/A