Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4e1o_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 3.A N GLU 6.A OE1 no hydrogen 2.759 N/A TYR 7.A N GLU 3.A O no hydrogen 2.865 N/A ARG 8.A N PRO 4.A O no hydrogen 3.055 N/A GLU 9.A N GLU 5.A O no hydrogen 3.173 N/A ARG 10.A N GLU 6.A O no hydrogen 2.779 N/A ARG 10.A NH1 GLU 13.A OE1.A no hydrogen 3.201 N/A ARG 10.A NH1 GLU 13.A OE1.B no hydrogen 3.286 N/A ARG 10.A NH1 ASP 55.A OD1 no hydrogen 3.409 N/A GLY 11.A N TYR 7.A O no hydrogen 2.644 N/A ARG 12.A N ARG 8.A O no hydrogen 3.193 N/A ARG 12.A NH1 ARG 8.A O no hydrogen 3.484 N/A GLU 13.A N GLU 9.A O no hydrogen 3.057 N/A MET 14.A N ARG 10.A O no hydrogen 2.899 N/A VAL 15.A N GLY 11.A O no hydrogen 2.884 N/A ASP 16.A N ARG 12.A O no hydrogen 2.980 N/A TYR 17.A N GLU 13.A O no hydrogen 2.889 N/A TYR 17.A OH GLU 62.A OE2 no hydrogen 2.652 N/A ILE 18.A N MET 14.A O no hydrogen 2.840 N/A CYS 19.A N VAL 15.A O no hydrogen 2.950 N/A GLN 20.A N ASP 16.A O no hydrogen 3.124 N/A TYR 21.A N TYR 17.A O no hydrogen 2.821 N/A TYR 21.A OH HIS 71.A ND1 no hydrogen 2.653 N/A LEU 22.A N ILE 18.A O no hydrogen 2.893 N/A SER 23.A N CYS 19.A O no hydrogen 3.025 N/A SER 23.A OG CYS 19.A O no hydrogen 2.702 N/A THR 24.A N GLN 20.A O no hydrogen 3.042 N/A THR 24.A OG1 GLN 20.A O no hydrogen 2.741 N/A ARG 26.A NE ASP 458.A OD1 no hydrogen 2.800 N/A ARG 26.A NE ASP 458.A OD2 no hydrogen 3.240 N/A ARG 26.A NH2 ASP 458.A OD2 no hydrogen 2.816 N/A GLU 27.A N THR 24.A O no hydrogen 2.962 N/A ARG 28.A N VAL 25.A O no hydrogen 3.085 N/A ARG 28.A NH1 GLU 62.A OE1 no hydrogen 3.053 N/A ARG 28.A NH2 GLU 62.A OE2 no hydrogen 2.791 N/A ARG 29.A NE THR 31.A O no hydrogen 2.704 N/A ARG 29.A NH1 LYS 428.A O no hydrogen 3.381 N/A ARG 29.A NH2 LYS 428.A O no hydrogen 2.926 N/A VAL 30.A N GLY 430.A O no hydrogen 2.928 N/A THR 31.A N GLY 430.A O no hydrogen 3.414 N/A TYR 38.A N GLN 35.A O no hydrogen 3.183 N/A ARG 40.A NE GLU 45.A OE2 no hydrogen 3.283 N/A ARG 40.A NH2 GLU 45.A OE1 no hydrogen 3.410 N/A GLN 42.A N LEU 39.A O no hydrogen 2.911 N/A LEU 43.A N ARG 40.A O no hydrogen 3.274 N/A SER 56.A N SER 53.A OG no hydrogen 3.055 N/A ILE 57.A N SER 53.A O no hydrogen 3.023 N/A PHE 58.A N TRP 54.A O no hydrogen 2.759 N/A GLY 59.A N ASP 55.A O no hydrogen 2.863 N/A ASP 60.A N SER 56.A O no hydrogen 3.045 N/A ASP 60.A N ILE 57.A O no hydrogen 3.291 N/A ILE 61.A N PHE 58.A O no hydrogen 3.087 N/A ARG 63.A N GLY 59.A O no hydrogen 3.227 N/A ARG 63.A NE ASP 60.A OD1 no hydrogen 3.022 N/A ARG 63.A NH2 ASP 60.A OD1 no hydrogen 2.987 N/A ILE 64.A N ASP 60.A O no hydrogen 2.961 N/A ILE 65.A N ASP 60.A O no hydrogen 3.079 N/A MET 66.A N ILE 61.A O no hydrogen 2.827 N/A GLY 68.A N ILE 65.A O no hydrogen 3.136 N/A VAL 69.A N MET 66.A O no hydrogen 3.097 N/A HIS 71.A N VAL 30.A O no hydrogen 3.110 N/A HIS 71.A ND1 TYR 21.A OH no hydrogen 2.653 N/A TRP 72.A N VAL 70.A O no hydrogen 3.007 N/A GLN 73.A NE2 ALA 83.A O no hydrogen 2.788 N/A SER 74.A N HIS 71.A O no hydrogen 2.977 N/A HIS 76.A N SER 74.A OG no hydrogen 2.907 N/A HIS 76.A ND1 ASP 462.A OD2 no hydrogen 2.860 N/A MET 77.A N SER 74.A O no hydrogen 2.889 N/A HIS 78.A N PHE 433.A O no hydrogen 2.888 N/A HIS 78.A ND1 THR 448.A O no hydrogen 2.739 N/A HIS 78.A NE2 ASP 462.A OD2 no hydrogen 2.662 N/A TYR 81.A OH THR 247.A O no hydrogen 2.610 N/A LEU 84.A N LYS 304.A O no hydrogen 3.161 N/A THR 85.A N GLN 73.A OE1 no hydrogen 2.979 N/A SER 86.A OG MET 307.A O no hydrogen 2.700 N/A SER 89.A OG HIS 309.A ND1 no hydrogen 2.752 N/A LEU 90.A N SER 86.A O no hydrogen 3.082 N/A LEU 91.A N TRP 87.A O no hydrogen 3.152 N/A GLY 92.A N PRO 88.A O no hydrogen 3.011 N/A ASP 93.A N SER 89.A O no hydrogen 3.194 N/A MET 94.A N LEU 90.A O no hydrogen 3.086 N/A LEU 95.A N LEU 91.A O no hydrogen 3.401 N/A ALA 96.A N GLY 92.A O no hydrogen 3.157 N/A ASP 97.A N ASP 93.A O no hydrogen 2.788 N/A ALA 98.A N MET 94.A O no hydrogen 3.255 N/A ILE 99.A N LEU 95.A O no hydrogen 2.976 N/A ASN 100.A N ALA 96.A O no hydrogen 2.791 N/A CYS 101.A SG SER 109.A OG no hydrogen 3.303 N/A GLY 103.A N ARG 354.A O no hydrogen 2.948 N/A THR 105.A N SER 108.A OG no hydrogen 3.311 N/A TRP 106.A N ASP 344.A OD1 no hydrogen 2.865 N/A TRP 106.A NE1 GLU 114.A OE2 no hydrogen 2.800 N/A SER 108.A N THR 105.A O no hydrogen 3.251 N/A SER 108.A N THR 105.A OG1 no hydrogen 3.132 N/A SER 108.A OG LEU 102.A O no hydrogen 2.807 N/A SER 108.A OG THR 105.A O no hydrogen 3.005 N/A CYS 112.A N SER 109.A O no hydrogen 2.948 N/A THR 113.A N PRO 110.A O no hydrogen 3.041 N/A GLU 114.A N PRO 110.A O no hydrogen 2.883 N/A LEU 115.A N ALA 111.A O no hydrogen 2.950 N/A MET 117.A N THR 113.A O no hydrogen 2.945 N/A ASN 118.A N GLU 114.A O no hydrogen 3.140 N/A ASN 118.A ND2 GLU 114.A O no hydrogen 2.820 N/A VAL 119.A N LEU 115.A O no hydrogen 2.877 N/A MET 120.A N GLU 116.A O no hydrogen 2.844 N/A ASP 121.A N MET 117.A O no hydrogen 3.116 N/A TRP 122.A N ASN 118.A O no hydrogen 3.032 N/A LEU 123.A N VAL 119.A O no hydrogen 2.889 N/A ALA 124.A N MET 120.A O no hydrogen 2.931 N/A LYS 125.A N ASP 121.A O no hydrogen 3.092 N/A MET 126.A N TRP 122.A O no hydrogen 2.936 N/A LEU 127.A N LEU 123.A O no hydrogen 2.973 N/A GLY 128.A N LYS 125.A O no hydrogen 3.129 N/A LEU 129.A N ALA 124.A O no hydrogen 3.026 N/A PHE 133.A N PRO 130.A O no hydrogen 3.099 N/A LEU 134.A N GLU 131.A O no hydrogen 3.017 N/A HIS 135.A N ASP 121.A OD1 no hydrogen 2.767 N/A HIS 135.A NE2 GLY 144.A O no hydrogen 2.697 N/A HIS 136.A N ASP 121.A OD2 no hydrogen 3.076 N/A HIS 137.A ND1 SER 139.A OG no hydrogen 2.746 N/A SER 139.A N HIS 137.A ND1 no hydrogen 3.366 N/A SER 139.A OG HIS 137.A ND1 no hydrogen 2.746 N/A SER 140.A N HIS 137.A O no hydrogen 3.108 N/A SER 140.A OG HIS 132.A O no hydrogen 3.243 N/A SER 140.A OG LEU 134.A O no hydrogen 2.561 N/A SER 140.A OG GLY 142.A O no hydrogen 3.495 N/A GLY 142.A N SER 140.A OG no hydrogen 2.942 N/A GLY 143.A N VAL 317.A O no hydrogen 2.987 N/A VAL 145.A N PHE 315.A O no hydrogen 2.779 N/A LEU 146.A N GLU 116.A OE2 no hydrogen 2.713 N/A GLN 147.A N THR 313.A O no hydrogen 2.786 N/A GLN 147.A NE2 TRP 348.A O no hydrogen 3.005 N/A SER 148.A OG ASP 311.A OD2 no hydrogen 2.763 N/A THR 149.A OG1 GLU 152.A OE2 no hydrogen 2.586 N/A GLU 152.A N THR 149.A OG1 no hydrogen 2.966 N/A SER 153.A N THR 149.A O no hydrogen 3.214 N/A SER 153.A OG THR 149.A O no hydrogen 2.986 N/A THR 154.A N VAL 150.A O no hydrogen 2.771 N/A THR 154.A OG1 VAL 150.A O no hydrogen 3.273 N/A THR 154.A OG1 HIS 270.A NE2 no hydrogen 2.938 N/A LEU 155.A N SER 151.A O no hydrogen 3.036 N/A ILE 156.A N GLU 152.A O no hydrogen 2.853 N/A ALA 157.A N SER 153.A O no hydrogen 2.985 N/A LEU 158.A N THR 154.A O no hydrogen 3.004 N/A LEU 159.A N LEU 155.A O no hydrogen 2.789 N/A ALA 160.A N ILE 156.A O no hydrogen 2.803 N/A ALA 161.A N ALA 157.A O no hydrogen 2.875 N/A ARG 162.A N LEU 158.A O no hydrogen 2.856 N/A ARG 162.A NH1 ASN 182.A OD1 no hydrogen 2.876 N/A ARG 162.A NH1 SER 204.A O no hydrogen 2.849 N/A LYS 163.A N LEU 159.A O no hydrogen 2.952 N/A LYS 163.A NZ GLU 178.A OE1 no hydrogen 3.204 N/A LYS 163.A NZ GLU 178.A OE2 no hydrogen 2.635 N/A ASN 164.A N ALA 160.A O no hydrogen 2.937 N/A LYS 165.A N ALA 161.A O no hydrogen 3.061 N/A LYS 165.A NZ GLU 168.A OE1 no hydrogen 3.332 N/A ILE 166.A N ARG 162.A O no hydrogen 2.840 N/A LEU 167.A N LYS 163.A O no hydrogen 2.950 N/A GLU 168.A N ASN 164.A O no hydrogen 3.141 N/A MET 169.A N LYS 165.A O no hydrogen 2.927 N/A LYS 170.A N ILE 166.A O no hydrogen 2.798 N/A LYS 170.A NZ PRO 174.A O no hydrogen 2.971 N/A LYS 170.A NZ ALA 176.A O no hydrogen 2.862 N/A THR 171.A N LEU 167.A O no hydrogen 3.276 N/A THR 171.A N GLU 168.A O no hydrogen 3.277 N/A THR 171.A OG1 GLU 168.A O no hydrogen 2.790 N/A SER 172.A N MET 169.A O no hydrogen 3.149 N/A GLU 173.A N MET 169.A O no hydrogen 2.900 N/A ALA 176.A N GLU 173.A O no hydrogen 2.973 N/A SER 179.A N ASP 177.A OD1 no hydrogen 2.969 N/A LEU 181.A N ASP 177.A O no hydrogen 3.000 N/A ASN 182.A N GLU 178.A O no hydrogen 2.870 N/A ASN 182.A ND2 SER 204.A O no hydrogen 3.565 N/A ASN 182.A ND2 LEU 205.A O no hydrogen 3.061 N/A ALA 183.A N SER 179.A O no hydrogen 3.343 N/A ALA 183.A N SER 180.A O no hydrogen 3.233 N/A ARG 184.A N LEU 181.A O no hydrogen 3.035 N/A ARG 184.A NH1 GLU 173.A OE1 no hydrogen 2.762 N/A ARG 184.A NH2 GLU 173.A OE1 no hydrogen 3.297 N/A ARG 184.A NH2 GLU 173.A OE2 no hydrogen 3.063 N/A LEU 185.A N ASN 182.A O no hydrogen 3.094 N/A VAL 186.A N VAL 237.A O no hydrogen 3.025 N/A ALA 187.A N LYS 207.A O no hydrogen 2.787 N/A TYR 188.A N PHE 240.A O no hydrogen 2.918 N/A TYR 188.A OH ASP 231.A OD2 no hydrogen 2.612 N/A ALA 189.A N LYS 209.A O no hydrogen 3.200 N/A ASP 191.A N LEU 211.A O no hydrogen 2.861 N/A GLN 192.A N SER 190.A OG no hydrogen 2.830 N/A GLN 192.A NE2 ASP 191.A OD1 no hydrogen 2.967 N/A ALA 193.A N SER 190.A O no hydrogen 2.935 N/A HIS 194.A ND1 SER 196.A OG no hydrogen 2.819 N/A SER 196.A N HIS 194.A ND1 no hydrogen 3.050 N/A SER 196.A OG HIS 194.A ND1 no hydrogen 2.819 N/A VAL 197.A N HIS 194.A O no hydrogen 2.953 N/A LYS 199.A N SER 195.A O no hydrogen 2.852 N/A ALA 200.A N SER 196.A O no hydrogen 2.912 N/A GLY 201.A N VAL 197.A O no hydrogen 3.197 N/A LEU 202.A N GLU 198.A O no hydrogen 3.016 N/A ILE 203.A N LYS 199.A O no hydrogen 2.974 N/A SER 204.A N ALA 200.A O no hydrogen 3.018 N/A SER 204.A OG ALA 200.A O no hydrogen 2.739 N/A SER 204.A OG GLY 201.A O no hydrogen 3.531 N/A VAL 206.A N GLY 201.A O no hydrogen 3.107 N/A LYS 207.A NZ ALA 183.A O no hydrogen 2.722 N/A LYS 209.A N ALA 187.A O no hydrogen 2.817 N/A LYS 209.A NZ ASP 231.A OD1 no hydrogen 2.670 N/A LEU 211.A N ALA 189.A O no hydrogen 2.815 N/A ASP 214.A N SER 218.A O no hydrogen 2.959 N/A ASN 216.A N ASP 214.A OD1 no hydrogen 2.817 N/A PHE 217.A N ASP 214.A O no hydrogen 2.905 N/A SER 218.A N ASP 214.A OD1 no hydrogen 2.974 N/A SER 218.A OG PHE 253.A O no hydrogen 2.653 N/A LEU 219.A N ASP 254.A OD1 no hydrogen 2.959 N/A ARG 220.A NE GLU 257.A OE1 no hydrogen 2.911 N/A ARG 220.A NE GLU 257.A OE2 no hydrogen 3.457 N/A ARG 220.A NH1 ASP 214.A OD2 no hydrogen 3.079 N/A ARG 220.A NH2 GLU 257.A OE2 no hydrogen 2.809 N/A GLY 221.A N GLU 257.A OE1 no hydrogen 2.927 N/A LEU 224.A N ARG 220.A O no hydrogen 3.431 N/A GLN 225.A N GLY 221.A O no hydrogen 2.844 N/A GLN 225.A NE2 GLU 229.A OE2.A no hydrogen 3.058 N/A LYS 226.A N GLU 222.A O no hydrogen 2.978 N/A ALA 227.A N ALA 223.A O no hydrogen 3.068 N/A ILE 228.A N LEU 224.A O no hydrogen 2.936 N/A GLU 229.A N GLN 225.A O no hydrogen 3.115 N/A GLU 230.A N LYS 226.A O no hydrogen 3.041 N/A ASP 231.A N ALA 227.A O no hydrogen 2.938 N/A LYS 232.A N ILE 228.A O no hydrogen 2.988 N/A LYS 232.A NZ GLU 265.A OE1 no hydrogen 2.984 N/A GLN 233.A N GLU 229.A O no hydrogen 3.044 N/A GLN 233.A NE2 GLN 233.A O no hydrogen 2.975 N/A ARG 234.A N GLU 230.A O no hydrogen 3.292 N/A ARG 234.A N ASP 231.A O no hydrogen 3.038 N/A ARG 234.A NH2 ASP 231.A OD1 no hydrogen 2.960 N/A GLY 235.A N LYS 232.A O no hydrogen 3.070 N/A LEU 236.A N ASP 231.A O no hydrogen 2.910 N/A VAL 237.A N ARG 184.A O no hydrogen 2.749 N/A VAL 239.A N VAL 186.A O no hydrogen 2.913 N/A VAL 241.A N TRP 268.A O no hydrogen 2.817 N/A CYS 242.A N TYR 188.A O no hydrogen 2.934 N/A CYS 242.A SG ALA 243.A O no hydrogen 3.986 N/A CYS 242.A SG HIS 270.A O no hydrogen 3.908 N/A ALA 243.A N HIS 270.A O no hydrogen 2.883 N/A THR 244.A N ASP 254.A OD2 no hydrogen 2.737 N/A LEU 245.A N ASP 272.A O no hydrogen 2.858 N/A GLY 246.A N ALA 252.A O no hydrogen 2.835 N/A THR 247.A N ALA 252.A O no hydrogen 2.863 N/A CYS 251.A N THR 247.A O no hydrogen 2.829 N/A ALA 252.A N THR 247.A OG1 no hydrogen 2.847 N/A ASP 254.A N THR 244.A O no hydrogen 2.908 N/A GLY 259.A N LEU 255.A O no hydrogen 2.860 N/A CYS 262.A N LEU 258.A O no hydrogen 3.023 N/A CYS 262.A SG LEU 258.A O no hydrogen 3.421 N/A ALA 263.A N GLY 259.A O no hydrogen 2.994 N/A ARG 264.A N PRO 260.A O no hydrogen 3.004 N/A GLU 265.A N ILE 261.A O no hydrogen 2.872 N/A GLY 266.A N ALA 263.A O no hydrogen 3.396 N/A LEU 267.A N CYS 262.A O no hydrogen 2.850 N/A TRP 268.A N VAL 239.A O no hydrogen 3.064 N/A TRP 268.A NE1 SER 297.A OG no hydrogen 2.788 N/A LEU 269.A N ASP 296.A OD2 no hydrogen 2.861 N/A HIS 270.A N VAL 241.A O no hydrogen 2.878 N/A HIS 270.A ND1 SER 297.A OG no hydrogen 2.742 N/A HIS 270.A NE2 THR 154.A OG1 no hydrogen 2.938 N/A ILE 271.A N SER 297.A O no hydrogen 2.919 N/A ASP 272.A N ALA 243.A O no hydrogen 2.906 N/A ALA 273.A N THR 299.A O no hydrogen 2.826 N/A ALA 274.A N ASP 272.A OD1 no hydrogen 2.934 N/A GLY 277.A N ALA 273.A O no hydrogen 2.873 N/A THR 278.A N TYR 275.A O no hydrogen 3.391 N/A ALA 279.A N ALA 276.A O no hydrogen 2.881 N/A PHE 280.A N GLY 277.A O no hydrogen 3.021 N/A LEU 281.A N THR 278.A O no hydrogen 3.111 N/A CYS 282.A N ALA 279.A O no hydrogen 2.862 N/A CYS 282.A SG GLN 374.A O no hydrogen 3.600 N/A GLU 284.A N GLU 284.A OE1 no hydrogen 2.747 N/A PHE 285.A N CYS 282.A O no hydrogen 3.046 N/A ARG 286.A N PRO 283.A O no hydrogen 3.104 N/A ARG 286.A NE PHE 280.A O no hydrogen 2.785 N/A ARG 286.A NH2 PHE 280.A O no hydrogen 3.044 N/A LEU 289.A N ARG 286.A O no hydrogen 2.924 N/A LYS 290.A N GLY 287.A O no hydrogen 3.217 N/A ILE 292.A N LEU 289.A O no hydrogen 2.903 N/A GLU 293.A N GLU 293.A OE1 no hydrogen 2.819 N/A TYR 294.A N GLY 291.A O no hydrogen 3.001 N/A ALA 295.A N ILE 292.A O no hydrogen 2.973 N/A ASP 296.A N LEU 269.A O no hydrogen 2.794 N/A SER 297.A N LEU 269.A O no hydrogen 3.197 N/A SER 297.A OG HIS 270.A ND1 no hydrogen 2.742 N/A PHE 298.A N TRP 316.A O no hydrogen 2.992 N/A THR 299.A N ILE 271.A O no hydrogen 2.944 N/A THR 299.A OG1 GLY 314.A O no hydrogen 2.845 N/A PHE 300.A N GLY 314.A O no hydrogen 3.163 N/A ASN 301.A N ALA 274.A O no hydrogen 2.864 N/A SER 303.A N CYS 312.A O no hydrogen 3.221 N/A SER 303.A OG CYS 312.A O no hydrogen 3.345 N/A LYS 304.A N ASN 301.A O no hydrogen 2.951 N/A MET 306.A N PRO 302.A O no hydrogen 3.150 N/A HIS 309.A N SER 89.A OG no hydrogen 2.960 N/A HIS 309.A NE2 ASP 93.A OD2 no hydrogen 2.748 N/A ASP 311.A N ASP 311.A OD1 no hydrogen 2.623 N/A THR 313.A N GLN 147.A O no hydrogen 2.923 N/A THR 313.A OG1 ASN 301.A OD1 no hydrogen 2.466 N/A GLY 314.A N PHE 300.A O no hydrogen 2.903 N/A PHE 315.A N VAL 145.A O no hydrogen 3.027 N/A TRP 316.A N PHE 298.A O no hydrogen 2.864 N/A VAL 317.A N GLY 143.A O no hydrogen 2.988 N/A LYS 318.A N ASP 296.A O no hydrogen 2.987 N/A LYS 320.A N GLN 141.A O no hydrogen 2.872 N/A TYR 321.A N ASP 319.A OD1 no hydrogen 3.093 N/A LEU 323.A N ASP 319.A O no hydrogen 3.356 N/A GLN 324.A N LYS 320.A O no hydrogen 2.864 N/A GLN 325.A N TYR 321.A O no hydrogen 2.928 N/A GLN 325.A NE2 ASN 164.A OD1 no hydrogen 3.024 N/A THR 326.A N LEU 323.A O no hydrogen 3.143 N/A THR 326.A OG1 LYS 322.A O no hydrogen 2.984 N/A THR 326.A OG1 LEU 323.A O no hydrogen 3.010 N/A PHE 327.A N GLN 324.A O no hydrogen 3.505 N/A LEU 334.A N PRO 331.A O no hydrogen 3.037 N/A ARG 335.A N ILE 332.A O no hydrogen 3.030 N/A ARG 335.A NE ASN 330.A O no hydrogen 3.282 N/A ARG 335.A NE ASN 330.A OD1 no hydrogen 3.068 N/A ARG 335.A NH2 ASN 330.A O no hydrogen 2.767 N/A HIS 336.A NE2 ASP 344.A OD1 no hydrogen 2.929 N/A ASN 338.A N HIS 336.A ND1 no hydrogen 3.304 N/A SER 339.A N HIS 336.A O no hydrogen 3.201 N/A SER 339.A OG HIS 336.A O no hydrogen 2.784 N/A VAL 341.A N ASN 338.A O no hydrogen 3.233 N/A ALA 342.A N ASN 338.A O no hydrogen 2.880 N/A MET 346.A N PHE 104.A O no hydrogen 2.991 N/A HIS 347.A N ASP 344.A O no hydrogen 3.222 N/A TRP 348.A N PHE 345.A O no hydrogen 2.926 N/A GLN 349.A NE2 PRO 351.A O no hydrogen 2.975 N/A GLN 349.A NE2 SER 353.A O no hydrogen 3.568 N/A ARG 354.A NE GLN 349.A OE1 no hydrogen 2.800 N/A ARG 354.A NH1 GLU 116.A OE1 no hydrogen 2.999 N/A ARG 354.A NH1 GLU 116.A OE2 no hydrogen 3.416 N/A ARG 354.A NH2 GLU 116.A OE1 no hydrogen 3.502 N/A ARG 354.A NH2 GLU 116.A OE2 no hydrogen 2.798 N/A ARG 354.A NH2 LEU 146.A O no hydrogen 2.980 N/A ARG 355.A NH1 ASP 93.A OD1 no hydrogen 2.856 N/A ARG 355.A NH2 ASP 93.A OD1 no hydrogen 3.477 N/A ARG 355.A NH2 ASP 93.A OD2 no hydrogen 2.987 N/A ARG 355.A NH2 ASP 311.A OD1 no hydrogen 3.474 N/A ARG 357.A N ARG 355.A O no hydrogen 2.878 N/A ARG 357.A NE ASP 311.A OD2 no hydrogen 2.923 N/A ARG 357.A NH2 SER 148.A OG no hydrogen 2.825 N/A LYS 360.A NZ ASP 93.A OD2 no hydrogen 3.566 N/A LYS 360.A NZ HIS 309.A O no hydrogen 2.813 N/A LYS 360.A NZ ASP 311.A O no hydrogen 2.921 N/A TRP 362.A N SER 358.A O no hydrogen 2.881 N/A PHE 363.A N VAL 359.A O no hydrogen 2.826 N/A VAL 364.A N LYS 360.A O no hydrogen 2.898 N/A ILE 365.A N LEU 361.A O no hydrogen 3.030 N/A ARG 366.A N TRP 362.A O no hydrogen 2.951 N/A SER 367.A N PHE 363.A O no hydrogen 2.849 N/A PHE 368.A N VAL 364.A O no hydrogen 3.055 N/A GLY 369.A N ILE 365.A O no hydrogen 2.774 N/A ASN 372.A ND2 PHE 368.A O no hydrogen 3.007 N/A LEU 373.A N GLY 369.A O no hydrogen 3.238 N/A GLN 374.A N VAL 370.A O no hydrogen 2.911 N/A GLN 374.A NE2 LEU 281.A O no hydrogen 2.878 N/A ALA 375.A N LYS 371.A O no hydrogen 2.889 N/A HIS 376.A N ASN 372.A O no hydrogen 2.973 N/A HIS 376.A NE2 TRP 305.A O no hydrogen 2.776 N/A VAL 377.A N LEU 373.A O no hydrogen 3.122 N/A ARG 378.A N GLN 374.A O no hydrogen 2.980 N/A ARG 378.A NE GLU 284.A OE2 no hydrogen 2.738 N/A ARG 378.A NH2 GLU 284.A OE1 no hydrogen 2.953 N/A ARG 378.A NH2 GLU 284.A OE2 no hydrogen 3.459 N/A HIS 379.A N ALA 375.A O no hydrogen 2.858 N/A HIS 379.A NE2 THR 454.A O no hydrogen 2.724 N/A GLY 380.A N HIS 376.A O no hydrogen 2.946 N/A THR 381.A N VAL 377.A O no hydrogen 2.987 N/A THR 381.A OG1 VAL 377.A O no hydrogen 2.956 N/A GLU 382.A N ARG 378.A O no hydrogen 2.919 N/A MET 383.A N HIS 379.A O no hydrogen 2.865 N/A ALA 384.A N GLY 380.A O no hydrogen 3.020 N/A LYS 385.A N THR 381.A O no hydrogen 2.866 N/A TYR 386.A N GLU 382.A O no hydrogen 2.954 N/A PHE 387.A N MET 383.A O no hydrogen 3.039 N/A GLU 388.A N ALA 384.A O no hydrogen 2.829 N/A SER 389.A N LYS 385.A O no hydrogen 2.968 N/A SER 389.A OG LYS 385.A O no hydrogen 3.167 N/A LEU 390.A N TYR 386.A O no hydrogen 3.053 N/A VAL 391.A N PHE 387.A O no hydrogen 3.035 N/A ARG 392.A N GLU 388.A O no hydrogen 2.774 N/A ARG 392.A NH2 SER 389.A OG no hydrogen 2.903 N/A ASN 393.A N SER 389.A O no hydrogen 3.121 N/A ASN 393.A ND2 SER 389.A O no hydrogen 2.814 N/A ASP 394.A N VAL 391.A O no hydrogen 3.037 N/A SER 396.A N ASP 394.A OD1 no hydrogen 3.040 N/A PHE 397.A N ASP 394.A O no hydrogen 3.090 N/A GLU 398.A N ARG 411.A O no hydrogen 2.911 N/A ARG 403.A NE GLU 388.A OE1 no hydrogen 2.844 N/A ARG 403.A NH1 LEU 405.A O no hydrogen 2.969 N/A VAL 408.A N PHE 447.A O no hydrogen 2.940 N/A PHE 410.A N ILE 445.A O no hydrogen 3.016 N/A ARG 411.A N GLU 398.A O no hydrogen 3.059 N/A ARG 411.A NE LEU 443.A O no hydrogen 2.882 N/A ARG 411.A NH1 GLU 398.A OE2 no hydrogen 2.793 N/A ARG 411.A NH1 GLY 414.A O no hydrogen 3.089 N/A ARG 411.A NH2 GLY 414.A O no hydrogen 2.844 N/A ARG 411.A NH2 ASN 416.A OD1 no hydrogen 2.803 N/A LEU 412.A N THR 419.A OG1 no hydrogen 3.030 N/A LYS 413.A N SER 396.A O no hydrogen 2.814 N/A LYS 413.A NZ PRO 395.A O no hydrogen 2.889 N/A ASN 416.A ND2 ASP 441.A O no hydrogen 3.077 N/A LEU 418.A N PRO 415.A O no hydrogen 3.124 N/A GLU 420.A N ASN 416.A O no hydrogen 2.916 N/A ASN 421.A N SER 417.A O no hydrogen 2.855 N/A VAL 422.A N LEU 418.A O no hydrogen 2.963 N/A LEU 423.A N THR 419.A O no hydrogen 3.200 N/A LYS 424.A N GLU 420.A O no hydrogen 3.056 N/A LYS 424.A NZ GLU 420.A OE2.A no hydrogen 3.065 N/A GLU 425.A N ASN 421.A O no hydrogen 2.937 N/A ILE 426.A N VAL 422.A O no hydrogen 2.945 N/A ALA 427.A N LEU 423.A O no hydrogen 2.990 N/A LYS 428.A N GLU 425.A O no hydrogen 3.158 N/A LYS 428.A NZ GLU 425.A OE2 no hydrogen 3.528 N/A GLY 430.A N ILE 426.A O no hydrogen 3.179 N/A PHE 433.A N HIS 76.A O no hydrogen 3.156 N/A ALA 437.A N ILE 444.A O no hydrogen 2.996 N/A ILE 439.A N LYS 442.A O no hydrogen 2.942 N/A LYS 442.A N ILE 439.A O no hydrogen 2.942 N/A LEU 443.A N ASN 416.A OD1 no hydrogen 2.940 N/A ILE 444.A N ALA 437.A O no hydrogen 2.948 N/A ILE 445.A N PHE 410.A O no hydrogen 2.721 N/A ARG 446.A N ILE 435.A O no hydrogen 3.039 N/A ARG 446.A NE THR 248.A O no hydrogen 2.862 N/A ARG 446.A NE GLY 249.A O no hydrogen 3.335 N/A ARG 446.A NH1 TYR 80.A O no hydrogen 2.830 N/A ARG 446.A NH2 TYR 80.A O no hydrogen 3.103 N/A ARG 446.A NH2 THR 248.A O no hydrogen 2.917 N/A PHE 447.A N VAL 408.A O no hydrogen 2.756 N/A THR 448.A N HIS 78.A O no hydrogen 3.156 N/A THR 448.A OG1 TYR 80.A O no hydrogen 2.767 N/A VAL 449.A N GLY 406.A O no hydrogen 2.916 N/A THR 450.A OG1 SER 74.A O no hydrogen 3.360 N/A THR 450.A OG1 MET 77.A O no hydrogen 2.756 N/A SER 451.A N THR 450.A OG1 no hydrogen 2.717 N/A GLN 452.A N GLN 452.A OE1 no hydrogen 2.783 N/A GLN 452.A NE2 THR 85.A O no hydrogen 2.900 N/A PHE 453.A N SER 451.A OG no hydrogen 2.985 N/A THR 454.A N SER 451.A O no hydrogen 3.059 N/A THR 454.A OG1 SER 451.A O no hydrogen 2.730 N/A THR 455.A N ASP 458.A OD2 no hydrogen 2.975 N/A ASP 458.A N THR 455.A OG1 no hydrogen 3.332 N/A ILE 459.A N THR 455.A O no hydrogen 3.126 N/A LEU 460.A N ARG 456.A O no hydrogen 2.952 N/A ARG 461.A N ASP 457.A O no hydrogen 2.953 N/A ARG 461.A NH1 ARG 431.A O no hydrogen 2.913 N/A ARG 461.A NH1 ASP 462.A OD1 no hydrogen 2.882 N/A ASP 462.A N ASP 458.A O no hydrogen 3.043 N/A TRP 463.A N ILE 459.A O no hydrogen 2.852 N/A ASN 464.A N LEU 460.A O no hydrogen 2.827 N/A LEU 465.A N ARG 461.A O no hydrogen 3.135 N/A ILE 466.A N ASP 462.A O no hydrogen 3.068 N/A ARG 467.A N TRP 463.A O no hydrogen 2.759 N/A ARG 467.A NE ASP 394.A OD2 no hydrogen 2.770 N/A ARG 467.A NH1 THR 471.A OG1 no hydrogen 3.026 N/A ARG 467.A NH2 ASP 394.A OD1 no hydrogen 2.919 N/A ARG 467.A NH2 ASP 394.A OD2 no hydrogen 3.384 N/A ASP 468.A N ASN 464.A O no hydrogen 2.852 N/A ALA 469.A N LEU 465.A O no hydrogen 3.043 N/A ALA 470.A N ILE 466.A O no hydrogen 2.895 N/A THR 471.A N ARG 467.A O no hydrogen 2.840 N/A THR 471.A OG1 ARG 467.A O no hydrogen 3.056 N/A LEU 472.A N ASP 468.A O no hydrogen 3.137 N/A ILE 473.A N ALA 469.A O no hydrogen 2.982 N/A LEU 474.A N ALA 470.A O no hydrogen 2.873 N/A SER 475.A N THR 471.A O no hydrogen 3.256 N/A SER 475.A N LEU 472.A O no hydrogen 2.968 N/A SER 475.A OG LEU 472.A O no hydrogen 2.625 N/A GLN 476.A N ILE 473.A O no hydrogen 3.149 N/A