Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4e1z_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 4.A N ASP 2.A OD1 no hydrogen 3.165 N/A THR 4.A OG1 ASP 2.A OD1 no hydrogen 2.618 N/A VAL 5.A N ASP 2.A O no hydrogen 3.161 N/A PHE 6.A N CYS 79.A O no hydrogen 3.216 N/A HIS 7.A N TYR 30.A OH no hydrogen 3.493 N/A LYS 8.A NZ ASP 82.A OD2 no hydrogen 2.715 N/A TYR 10.A N HIS 7.A O no hydrogen 2.998 N/A LEU 11.A N LYS 8.A O no hydrogen 2.921 N/A LYS 12.A N CYS 29.A O no hydrogen 2.971 N/A LYS 12.A NZ ARG 9.A O no hydrogen 2.954 N/A LYS 12.A NZ LEU 11.A O no hydrogen 3.326 N/A LYS 13.A NZ ASP 16.A OD1 no hydrogen 2.991 N/A LYS 13.A NZ SER 26.A OG no hydrogen 3.167 N/A ILE 14.A N LEU 27.A O no hydrogen 2.873 N/A ARG 15.A NH2 TYR 91.A OH no hydrogen 3.569 N/A LEU 17.A N VAL 25.A O no hydrogen 2.772 N/A GLY 18.A N VAL 25.A O no hydrogen 3.105 N/A GLY 20.A N GLY 23.A O no hydrogen 3.001 N/A LYS 24.A N ALA 45.A O no hydrogen 2.863 N/A VAL 25.A N GLY 18.A O no hydrogen 2.773 N/A SER 26.A N VAL 43.A O no hydrogen 2.889 N/A SER 26.A OG ASP 16.A OD1 no hydrogen 3.412 N/A LEU 27.A N ARG 15.A O no hydrogen 2.767 N/A TYR 28.A N VAL 41.A O no hydrogen 2.916 N/A CYS 29.A N LYS 12.A O no hydrogen 2.801 N/A CYS 29.A SG THR 37.A O no hydrogen 3.555 N/A TYR 30.A N GLU 39.A O no hydrogen 2.630 N/A ASP 31.A N TYR 10.A O no hydrogen 3.106 N/A ASN 34.A N ASP 31.A O no hydrogen 3.259 N/A ASP 35.A N ASP 31.A OD1 no hydrogen 3.016 N/A GLY 38.A N ASP 35.A OD2 no hydrogen 2.892 N/A GLU 39.A N TYR 30.A O no hydrogen 2.886 N/A VAL 41.A N TYR 28.A O no hydrogen 2.922 N/A ALA 42.A N MET 89.A O no hydrogen 2.912 N/A VAL 43.A N SER 26.A O no hydrogen 2.871 N/A LYS 44.A N LEU 87.A O no hydrogen 2.868 N/A LYS 44.A NZ GLU 61.A OE2 no hydrogen 2.869 N/A LYS 44.A NZ ASP 152.A OD1 no hydrogen 2.739 N/A ALA 45.A N LYS 24.A O no hydrogen 2.834 N/A LYS 47.A N PHE 22.A O no hydrogen 2.657 N/A LYS 47.A NZ GLU 19.A OE2 no hydrogen 3.221 N/A LYS 47.A NZ GLY 20.A O no hydrogen 2.688 N/A CYS 50.A SG PHE 22.A O no hydrogen 3.618 N/A CYS 50.A SG LYS 47.A O no hydrogen 3.384 N/A ARG 55.A N GLY 51.A O no hydrogen 2.958 N/A SER 56.A N PRO 52.A O no hydrogen 3.203 N/A SER 56.A OG PRO 52.A O no hydrogen 3.237 N/A GLY 57.A N GLN 53.A O no hydrogen 3.243 N/A TRP 58.A N LEU 54.A O no hydrogen 2.887 N/A TRP 58.A NE1 VAL 85.A O no hydrogen 2.730 N/A ARG 60.A N SER 56.A O no hydrogen 3.231 N/A GLU 61.A N GLY 57.A O no hydrogen 2.818 N/A ILE 62.A N TRP 58.A O no hydrogen 3.112 N/A GLU 63.A N GLN 59.A O no hydrogen 3.134 N/A ILE 64.A N ARG 60.A O no hydrogen 2.897 N/A LEU 65.A N GLU 61.A O no hydrogen 3.150 N/A ARG 66.A N ILE 62.A O no hydrogen 3.033 N/A ARG 66.A NH1 GLU 63.A OE2 no hydrogen 3.477 N/A THR 67.A N GLU 63.A O no hydrogen 3.260 N/A THR 67.A N ILE 64.A O no hydrogen 3.221 N/A THR 67.A OG1 GLU 63.A O no hydrogen 2.975 N/A LEU 68.A N ILE 64.A O no hydrogen 3.100 N/A TYR 69.A N TYR 124.A OH no hydrogen 2.756 N/A HIS 72.A N HIS 70.A ND1 no hydrogen 2.971 N/A HIS 72.A ND1 VAL 148.A O no hydrogen 2.782 N/A ILE 73.A N HIS 70.A O no hydrogen 3.472 N/A VAL 74.A N ILE 150.A O no hydrogen 2.907 N/A LYS 75.A N GLU 90.A OE2 no hydrogen 2.976 N/A LYS 77.A N VAL 88.A O no hydrogen 2.816 N/A LYS 77.A NZ GLU 39.A OE2 no hydrogen 2.793 N/A GLY 78.A N VAL 88.A O no hydrogen 3.095 N/A CYS 79.A N THR 4.A O no hydrogen 3.012 N/A CYS 79.A SG TYR 76.A OH no hydrogen 3.805 N/A CYS 80.A N GLN 86.A O no hydrogen 2.966 N/A CYS 80.A SG PHE 6.A O no hydrogen 3.391 N/A ASP 82.A N SER 84.A O no hydrogen 2.897 N/A GLN 86.A N CYS 80.A O no hydrogen 2.949 N/A LEU 87.A N LYS 44.A O no hydrogen 2.881 N/A VAL 88.A N GLY 78.A O no hydrogen 2.880 N/A MET 89.A N ALA 42.A O no hydrogen 2.804 N/A GLU 90.A N LYS 75.A O no hydrogen 3.110 N/A LEU 94.A N LEU 142.A O no hydrogen 3.015 N/A LEU 97.A N VAL 140.A O no hydrogen 2.951 N/A ASP 99.A N SER 96.A O no hydrogen 3.041 N/A ASP 99.A N SER 96.A OG no hydrogen 3.394 N/A TYR 100.A N SER 96.A O no hydrogen 2.763 N/A LEU 101.A N LEU 97.A O no hydrogen 2.978 N/A HIS 104.A N LEU 101.A O no hydrogen 3.518 N/A HIS 104.A ND1 TYR 100.A O no hydrogen 2.660 N/A LEU 111.A N GLY 107.A O no hydrogen 2.952 N/A LEU 112.A N LEU 108.A O no hydrogen 2.797 N/A LEU 113.A N ALA 109.A O no hydrogen 2.885 N/A PHE 114.A N GLN 110.A O no hydrogen 2.898 N/A ALA 115.A N LEU 111.A O no hydrogen 2.997 N/A GLN 116.A N LEU 112.A O no hydrogen 3.036 N/A GLN 116.A NE2 GLN 284.A OE1 no hydrogen 3.476 N/A GLN 117.A N LEU 113.A O no hydrogen 3.173 N/A GLN 117.A NE2 LEU 113.A O no hydrogen 3.369 N/A ILE 118.A N PHE 114.A O no hydrogen 3.157 N/A CYS 119.A N ALA 115.A O no hydrogen 3.151 N/A CYS 119.A SG ALA 115.A O no hydrogen 3.338 N/A GLU 120.A N GLN 116.A O no hydrogen 2.992 N/A GLY 121.A N GLN 117.A O no hydrogen 3.066 N/A MET 122.A N ILE 118.A O no hydrogen 2.764 N/A ALA 123.A N CYS 119.A O no hydrogen 2.701 N/A TYR 124.A N GLU 120.A O no hydrogen 3.182 N/A LEU 125.A N GLY 121.A O no hydrogen 2.881 N/A HIS 126.A N MET 122.A O no hydrogen 3.011 N/A HIS 126.A NE2 ASP 194.A OD2 no hydrogen 3.001 N/A ALA 127.A N ALA 123.A O no hydrogen 2.984 N/A GLN 128.A N TYR 124.A O no hydrogen 2.998 N/A HIS 129.A N HIS 126.A O no hydrogen 3.262 N/A TYR 130.A N LEU 125.A O no hydrogen 3.002 N/A ILE 131.A N LYS 157.A O no hydrogen 2.981 N/A HIS 132.A N ASP 194.A OD2 no hydrogen 2.776 N/A ARG 133.A N ASP 194.A OD1 no hydrogen 3.147 N/A ALA 134.A N HIS 132.A ND1 no hydrogen 3.163 N/A ALA 137.A N GLU 204.A OE2 no hydrogen 2.853 N/A ASN 139.A N ALA 136.A O no hydrogen 2.837 N/A ASN 139.A ND2 ALA 134.A O no hydrogen 2.730 N/A VAL 140.A N ALA 137.A O no hydrogen 3.276 N/A LEU 141.A N LYS 149.A O no hydrogen 2.777 N/A LEU 142.A N GLY 95.A O no hydrogen 2.803 N/A ASP 143.A N LEU 147.A O no hydrogen 2.767 N/A ASN 144.A N ASP 143.A OD1 no hydrogen 2.870 N/A VAL 148.A N GLN 117.A OE1 no hydrogen 2.838 N/A LYS 149.A N LEU 141.A O no hydrogen 2.742 N/A LYS 149.A NZ GLU 90.A OE1 no hydrogen 3.132 N/A LYS 149.A NZ GLU 90.A OE2 no hydrogen 2.750 N/A LYS 149.A NZ ASP 143.A OD2 no hydrogen 2.971 N/A ILE 150.A N HIS 72.A O no hydrogen 2.880 N/A GLY 151.A N ASN 139.A O no hydrogen 2.696 N/A GLY 154.A N ASP 152.A OD2 no hydrogen 3.107 N/A ALA 156.A N PHE 153.A O no hydrogen 3.258 N/A LYS 157.A N ILE 131.A O no hydrogen 3.023 N/A LYS 157.A NZ LEU 155.A O no hydrogen 3.552 N/A LYS 157.A NZ ALA 156.A O no hydrogen 3.334 N/A VAL 159.A N HIS 129.A O no hydrogen 2.957 N/A TYR 166.A N PHE 189.A O no hydrogen 3.026 N/A ARG 167.A NH2 TYR 165.A OH no hydrogen 2.838 N/A VAL 168.A N CYS 187.A O no hydrogen 2.919 N/A ASP 171.A N GLN 229.A OE1 no hydrogen 3.005 N/A SER 174.A OG ASP 171.A O no hydrogen 2.874 N/A VAL 176.A N SER 174.A O no hydrogen 2.626 N/A TRP 178.A N PRO 175.A O no hydrogen 3.163 N/A TRP 178.A NE1 GLU 204.A OE2 no hydrogen 2.885 N/A TYR 179.A N VAL 176.A O no hydrogen 3.036 N/A TYR 179.A OH ARG 133.A O no hydrogen 2.571 N/A GLU 182.A N GLU 182.A OE1 no hydrogen 2.819 N/A CYS 183.A SG ALA 180.A O no hydrogen 3.466 N/A LEU 184.A N ALA 180.A O no hydrogen 3.373 N/A LYS 185.A N PRO 181.A O no hydrogen 2.621 N/A LYS 185.A NZ GLU 240.A OE2 no hydrogen 2.760 N/A GLU 186.A N GLU 182.A O no hydrogen 3.009 N/A PHE 189.A N TYR 166.A O no hydrogen 2.909 N/A TYR 190.A N SER 193.A OG no hydrogen 2.765 N/A TYR 191.A N GLU 164.A O no hydrogen 3.332 N/A SER 193.A N TYR 190.A O no hydrogen 2.998 N/A SER 193.A OG GLU 182.A OE2 no hydrogen 2.671 N/A SER 193.A OG TYR 190.A O no hydrogen 3.266 N/A ASP 194.A N TYR 191.A O no hydrogen 3.107 N/A TRP 196.A N ALA 192.A O no hydrogen 3.260 N/A SER 197.A N SER 193.A O no hydrogen 3.367 N/A SER 197.A OG TRP 178.A O no hydrogen 2.611 N/A SER 197.A OG SER 193.A O no hydrogen 3.406 N/A PHE 198.A N ASP 194.A O no hydrogen 2.915 N/A GLY 199.A N VAL 195.A O no hydrogen 3.107 N/A VAL 200.A N TRP 196.A O no hydrogen 3.272 N/A THR 201.A N SER 197.A O no hydrogen 2.986 N/A THR 201.A OG1 LEU 135.A O no hydrogen 2.811 N/A THR 201.A OG1 SER 197.A O no hydrogen 3.171 N/A LEU 202.A N PHE 198.A O no hydrogen 2.758 N/A TYR 203.A N GLY 199.A O no hydrogen 3.025 N/A TYR 203.A OH GLN 213.A O no hydrogen 2.570 N/A GLU 204.A N VAL 200.A O no hydrogen 2.885 N/A LEU 205.A N THR 201.A O no hydrogen 2.904 N/A LEU 206.A N LEU 202.A O no hydrogen 2.975 N/A THR 207.A N TYR 203.A O no hydrogen 3.016 N/A THR 207.A N GLU 204.A O no hydrogen 3.250 N/A THR 207.A OG1 TYR 203.A O no hydrogen 2.986 N/A THR 207.A OG1 GLU 204.A O no hydrogen 2.929 N/A TYR 208.A N LEU 205.A O no hydrogen 2.954 N/A TYR 208.A OH VAL 106.A O no hydrogen 2.459 N/A CYS 209.A N GLU 204.A O no hydrogen 2.839 N/A CYS 209.A SG LEU 97.A O no hydrogen 3.915 N/A CYS 209.A SG GLU 204.A O no hydrogen 3.965 N/A ASP 210.A N THR 207.A O no hydrogen 2.878 N/A ASN 212.A N ASP 210.A OD1 no hydrogen 3.178 N/A ASN 212.A ND2 ASP 210.A OD1 no hydrogen 2.926 N/A GLN 213.A N ASP 210.A O no hydrogen 3.004 N/A GLN 213.A NE2 ASP 210.A OD2 no hydrogen 2.748 N/A SER 214.A OG SER 211.A O no hydrogen 3.327 N/A THR 217.A N SER 214.A OG no hydrogen 3.350 N/A THR 217.A OG1 SER 211.A O no hydrogen 3.353 N/A LYS 218.A N SER 214.A O no hydrogen 2.960 N/A LYS 218.A NZ GLU 221.A OE1 no hydrogen 3.479 N/A PHE 219.A N PRO 215.A O no hydrogen 2.796 N/A THR 220.A N HIS 216.A O no hydrogen 2.756 N/A THR 220.A OG1 HIS 216.A O no hydrogen 2.622 N/A GLU 221.A N THR 217.A O no hydrogen 2.947 N/A ILE 223.A N PHE 219.A O no hydrogen 2.850 N/A GLY 224.A N THR 220.A O no hydrogen 2.755 N/A THR 226.A OG1 THR 231.A OG1 no hydrogen 2.784 N/A MET 230.A N GLN 227.A O no hydrogen 3.119 N/A THR 231.A N GLN 227.A O no hydrogen 3.442 N/A THR 231.A OG1 THR 226.A OG1 no hydrogen 2.784 N/A VAL 232.A N GLY 228.A O no hydrogen 3.465 N/A LEU 233.A N GLN 229.A O no hydrogen 3.022 N/A ARG 234.A N MET 230.A O no hydrogen 3.042 N/A ARG 234.A NH1 GLU 237.A OE1 no hydrogen 2.836 N/A LEU 235.A N THR 231.A O no hydrogen 3.014 N/A THR 236.A N VAL 232.A O no hydrogen 3.094 N/A THR 236.A OG1 VAL 232.A O no hydrogen 2.556 N/A GLU 237.A N LEU 233.A O no hydrogen 3.008 N/A LEU 238.A N ARG 234.A O no hydrogen 3.171 N/A LEU 239.A N LEU 235.A O no hydrogen 2.874 N/A GLU 240.A N THR 236.A O no hydrogen 3.186 N/A ARG 241.A NH1 GLU 243.A OE2 no hydrogen 3.452 N/A GLY 242.A N LEU 239.A O no hydrogen 2.795 N/A GLU 243.A N LEU 238.A O no hydrogen 3.141 N/A ARG 244.A NE TRP 263.A O no hydrogen 2.878 N/A ARG 244.A NH1 LEU 239.A O no hydrogen 2.897 N/A ARG 244.A NH1 GLU 243.A O no hydrogen 2.787 N/A ARG 244.A NH2 TRP 263.A O no hydrogen 3.059 N/A ARG 247.A NE CYS 251.A O no hydrogen 2.684 N/A ARG 247.A NH2 CYS 251.A O no hydrogen 3.385 N/A CYS 251.A N PRO 248.A O no hydrogen 3.156 N/A CYS 251.A SG PRO 252.A O no hydrogen 3.672 N/A ILE 255.A N PRO 252.A O no hydrogen 2.842 N/A TYR 256.A N PRO 252.A O no hydrogen 3.376 N/A TYR 256.A OH LEU 245.A O no hydrogen 2.890 N/A HIS 257.A N CYS 253.A O no hydrogen 2.917 N/A LEU 258.A N GLU 254.A O no hydrogen 3.315 N/A MET 259.A N ILE 255.A O no hydrogen 3.058 N/A LYS 260.A N TYR 256.A O no hydrogen 2.838 N/A ASN 261.A N HIS 257.A O no hydrogen 2.834 N/A CYS 262.A N LEU 258.A O no hydrogen 3.231 N/A CYS 262.A N MET 259.A O no hydrogen 2.946 N/A CYS 262.A SG LEU 258.A O no hydrogen 3.322 N/A TRP 263.A N LYS 260.A O no hydrogen 3.146 N/A SER 268.A N GLU 266.A OE2 no hydrogen 3.407 N/A SER 268.A OG GLU 266.A OE2 no hydrogen 2.750 N/A PHE 269.A N GLU 266.A O no hydrogen 2.819 N/A ARG 270.A N ALA 267.A O no hydrogen 3.171 N/A ARG 270.A NE GLU 264.A O no hydrogen 2.725 N/A ARG 270.A NH1 GLU 182.A OE1 no hydrogen 3.529 N/A ARG 270.A NH1 GLU 182.A OE2 no hydrogen 2.930 N/A ARG 270.A NH1 ALA 192.A O no hydrogen 3.097 N/A ARG 270.A NH2 GLU 182.A OE1 no hydrogen 3.032 N/A ARG 270.A NH2 GLU 264.A O no hydrogen 2.857 N/A THR 272.A N ASN 275.A OD1 no hydrogen 3.075 N/A ASN 275.A N THR 272.A OG1 no hydrogen 3.139 N/A LEU 276.A N THR 272.A O no hydrogen 2.881 N/A VAL 277.A N PHE 273.A O no hydrogen 3.142 N/A LEU 280.A N LEU 276.A O no hydrogen 3.066 N/A GLN 281.A N VAL 277.A O no hydrogen 3.098 N/A THR 282.A N PRO 278.A O no hydrogen 3.131 N/A THR 282.A OG1 PRO 278.A O no hydrogen 3.246 N/A ALA 283.A N ILE 279.A O no hydrogen 3.019 N/A GLN 284.A N LEU 280.A O no hydrogen 2.704 N/A GLU 285.A N GLN 281.A O no hydrogen 2.918 N/A LYS 286.A N THR 282.A O no hydrogen 2.847 N/A TYR 287.A N ALA 283.A O no hydrogen 3.439 N/A