Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4e8f_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 8.A N HIS 4.A O no hydrogen 2.781 N/A THR 8.A OG1 SER 3.A O no hydrogen 3.416 N/A THR 8.A OG1 HIS 4.A O no hydrogen 2.840 N/A THR 8.A OG1 SER 227.A OG no hydrogen 3.167 N/A LYS 9.A N LYS 5.A O no hydrogen 2.990 N/A PHE 10.A N GLU 6.A O no hydrogen 3.094 N/A CYS 11.A N PHE 7.A O no hydrogen 2.896 N/A CYS 11.A SG PHE 7.A O no hydrogen 3.231 N/A TYR 12.A N THR 8.A O no hydrogen 3.064 N/A GLU 13.A N LYS 9.A O no hydrogen 3.096 N/A VAL 14.A N PHE 10.A O no hydrogen 3.019 N/A TYR 15.A N CYS 11.A O no hydrogen 2.969 N/A ASN 16.A N TYR 12.A O no hydrogen 3.065 N/A GLU 17.A N VAL 14.A O no hydrogen 2.929 N/A ILE 18.A N VAL 14.A O no hydrogen 2.965 N/A LYS 19.A N TYR 15.A O no hydrogen 2.989 N/A GLU 24.A N SER 21.A OG no hydrogen 3.074 N/A PHE 25.A N SER 21.A O no hydrogen 3.115 N/A LYS 26.A N ASP 22.A O no hydrogen 3.087 N/A LYS 26.A NZ ASP 22.A OD2 no hydrogen 2.825 N/A GLU 27.A N LYS 23.A O no hydrogen 3.117 N/A LYS 28.A N GLU 24.A O no hydrogen 3.087 N/A LYS 28.A NZ GLU 24.A OE2 no hydrogen 3.265 N/A LYS 28.A NZ SER 63.A O no hydrogen 3.054 N/A ARG 29.A N PHE 25.A O no hydrogen 3.112 N/A ARG 29.A NH1 GLU 55.A OE1 no hydrogen 3.362 N/A ALA 30.A N LYS 26.A O no hydrogen 3.004 N/A ALA 31.A N GLU 27.A O no hydrogen 2.962 N/A LEU 32.A N LYS 28.A O no hydrogen 2.958 N/A ASP 33.A N ARG 29.A O no hydrogen 2.970 N/A THR 34.A N ALA 30.A O no hydrogen 3.049 N/A THR 34.A OG1 ALA 30.A O no hydrogen 3.097 N/A LEU 35.A N ALA 31.A O no hydrogen 3.037 N/A ARG 36.A N LEU 32.A O no hydrogen 2.912 N/A ARG 36.A NH1 LEU 48.A O no hydrogen 2.791 N/A LEU 37.A N THR 34.A O no hydrogen 3.065 N/A LEU 39.A N LEU 35.A O no hydrogen 3.265 N/A LYS 40.A N ARG 36.A O no hydrogen 3.109 N/A ARG 41.A N LEU 37.A O no hydrogen 3.350 N/A SER 43.A N LEU 39.A O no hydrogen 2.884 N/A ALA 46.A N SER 43.A O no hydrogen 3.353 N/A GLU 47.A N LEU 70.A O no hydrogen 3.004 N/A VAL 49.A N CYS 68.A O no hydrogen 2.837 N/A PHE 51.A N ASP 66.A O no hydrogen 2.947 N/A GLY 52.A N THR 132.A OG1 no hydrogen 2.857 N/A GLU 55.A N GLY 52.A O no hydrogen 2.978 N/A SER 56.A N GLY 52.A O no hydrogen 3.207 N/A SER 56.A OG GLY 52.A O no hydrogen 3.379 N/A SER 56.A OG SER 53.A O no hydrogen 3.398 N/A LEU 58.A N SER 53.A O no hydrogen 2.771 N/A LYS 61.A N ILE 18.A O no hydrogen 3.101 N/A LYS 61.A NZ GLU 17.A O no hydrogen 2.922 N/A ASN 62.A N GLU 24.A OE1 no hydrogen 2.928 N/A SER 63.A N GLU 24.A OE2 no hydrogen 3.341 N/A SER 63.A OG LEU 60.A O no hydrogen 2.961 N/A LEU 67.A N ASP 120.A O no hydrogen 2.667 N/A CYS 68.A N VAL 49.A O no hydrogen 2.856 N/A VAL 69.A N GLY 122.A O no hydrogen 2.807 N/A LEU 70.A N GLU 47.A O no hydrogen 2.710 N/A MET 71.A N ASN 124.A OD1 no hydrogen 3.100 N/A THR 76.A OG1 ASP 75.A OD2 no hydrogen 3.543 N/A GLN 80.A N THR 76.A O no hydrogen 3.425 N/A PHE 81.A N ILE 77.A O no hydrogen 2.616 N/A TYR 82.A N ALA 78.A O no hydrogen 3.057 N/A TYR 82.A OH GLY 92.A O no hydrogen 2.771 N/A GLU 83.A N LEU 79.A O no hydrogen 3.220 N/A GLU 84.A N GLN 80.A O no hydrogen 3.254 N/A LEU 85.A N PHE 81.A O no hydrogen 3.109 N/A ILE 86.A N TYR 82.A O no hydrogen 3.018 N/A ALA 87.A N GLU 83.A O no hydrogen 3.004 N/A GLU 88.A N GLU 84.A O no hydrogen 2.887 N/A GLU 88.A N LEU 85.A O no hydrogen 3.155 N/A GLY 89.A N ILE 86.A O no hydrogen 3.173 N/A PHE 90.A N LEU 85.A O no hydrogen 2.985 N/A GLU 91.A N SER 107.A O no hydrogen 3.076 N/A LYS 93.A N LYS 104.A O no hydrogen 2.805 N/A LEU 95.A N ILE 102.A O no hydrogen 2.879 N/A ILE 100.A N ARG 97.A O no hydrogen 3.175 N/A ILE 102.A N LEU 95.A O no hydrogen 2.903 N/A ILE 103.A N ILE 121.A O no hydrogen 2.912 N/A LYS 104.A N LYS 93.A O no hydrogen 2.907 N/A LEU 105.A N CYS 119.A O no hydrogen 2.758 N/A THR 106.A N GLU 91.A O no hydrogen 3.076 N/A SER 107.A N GLU 91.A O no hydrogen 3.404 N/A THR 109.A N GLY 89.A O no hydrogen 2.728 N/A THR 109.A OG1 GLY 89.A O no hydrogen 3.064 N/A CYS 119.A N LEU 105.A O no hydrogen 2.959 N/A CYS 119.A SG MET 65.A O no hydrogen 4.037 N/A ASP 120.A N MET 65.A O no hydrogen 2.886 N/A ILE 121.A N ILE 103.A O no hydrogen 2.771 N/A GLY 122.A N LEU 67.A O no hydrogen 2.945 N/A ASN 124.A N VAL 69.A O no hydrogen 2.838 N/A ARG 126.A NH1 ASN 124.A OD1 no hydrogen 2.961 N/A ARG 126.A NH2 MET 71.A O no hydrogen 2.872 N/A ALA 128.A N ASN 125.A OD1 no hydrogen 3.445 N/A ILE 129.A N ARG 126.A O no hydrogen 3.178 N/A HIS 130.A N ARG 126.A O no hydrogen 3.303 N/A HIS 130.A ND1 ARG 126.A O no hydrogen 3.019 N/A ASN 131.A N LEU 127.A O no hydrogen 3.059 N/A THR 132.A N ALA 128.A O no hydrogen 3.151 N/A THR 132.A OG1 ALA 128.A O no hydrogen 3.156 N/A LEU 133.A N ILE 129.A O no hydrogen 3.082 N/A LEU 134.A N HIS 130.A O no hydrogen 3.067 N/A LEU 135.A N ASN 131.A O no hydrogen 3.098 N/A SER 136.A N THR 132.A O no hydrogen 2.815 N/A SER 136.A OG GLU 55.A O no hydrogen 3.533 N/A SER 136.A OG THR 132.A O no hydrogen 3.070 N/A SER 137.A N LEU 133.A O no hydrogen 3.010 N/A SER 137.A OG LEU 133.A O no hydrogen 2.811 N/A TYR 138.A N LEU 134.A O no hydrogen 3.257 N/A TYR 138.A OH PRO 192.A O no hydrogen 2.917 N/A THR 139.A N LEU 135.A O no hydrogen 3.213 N/A THR 139.A OG1 SER 136.A O no hydrogen 2.510 N/A LYS 140.A N SER 136.A O no hydrogen 3.129 N/A LEU 141.A N TYR 138.A O no hydrogen 3.193 N/A ASP 142.A N TYR 138.A O no hydrogen 3.359 N/A ARG 144.A N ASP 142.A OD2 no hydrogen 2.990 N/A ARG 144.A NE ASP 142.A OD2 no hydrogen 2.799 N/A ARG 144.A NH1 ASN 224.A O no hydrogen 3.024 N/A ARG 144.A NH1 SER 226.A O no hydrogen 2.582 N/A ARG 144.A NH2 ASP 142.A OD1 no hydrogen 2.814 N/A ARG 144.A NH2 ASN 224.A O no hydrogen 2.869 N/A LEU 145.A N ASP 142.A O no hydrogen 3.457 N/A MET 148.A N ARG 144.A O no hydrogen 3.231 N/A VAL 149.A N LEU 145.A O no hydrogen 2.904 N/A LEU 150.A N LYS 146.A O no hydrogen 3.073 N/A LEU 151.A N PRO 147.A O no hydrogen 2.988 N/A VAL 152.A N MET 148.A O no hydrogen 3.067 N/A LYS 153.A N VAL 149.A O no hydrogen 2.931 N/A LYS 153.A NZ LEU 58.A O no hydrogen 2.783 N/A HIS 154.A N LEU 150.A O no hydrogen 2.866 N/A TRP 155.A N LEU 151.A O no hydrogen 2.977 N/A ALA 156.A N VAL 152.A O no hydrogen 2.855 N/A LYS 157.A N LYS 153.A O no hydrogen 2.975 N/A ARG 158.A N HIS 154.A O no hydrogen 2.976 N/A ARG 158.A NH1 PHE 321.A O no hydrogen 2.705 N/A LYS 159.A N TRP 155.A O no hydrogen 2.894 N/A LYS 159.A NZ SER 319.A O no hydrogen 2.777 N/A LYS 159.A NZ GLU 322.A O no hydrogen 2.816 N/A GLN 160.A N LYS 157.A O no hydrogen 3.220 N/A GLN 160.A NE2 ALA 324.A O no hydrogen 3.378 N/A ILE 161.A N ALA 156.A O no hydrogen 2.888 N/A ASN 162.A ND2 SER 171.A OG no hydrogen 3.400 N/A SER 163.A N THR 168.A OG1 no hydrogen 3.126 N/A PHE 166.A N SER 163.A O no hydrogen 3.004 N/A THR 168.A N SER 163.A O no hydrogen 3.018 N/A THR 168.A OG1 SER 163.A O no hydrogen 3.028 N/A SER 171.A OG ASN 162.A OD1 no hydrogen 3.243 N/A TYR 172.A OH ASP 277.A OD2 no hydrogen 2.961 N/A GLY 173.A N SER 170.A OG no hydrogen 3.230 N/A TYR 174.A N SER 170.A O no hydrogen 3.317 N/A TYR 174.A OH ILE 161.A O no hydrogen 2.673 N/A VAL 175.A N SER 171.A O no hydrogen 3.081 N/A LEU 176.A N TYR 172.A O no hydrogen 3.085 N/A MET 177.A N GLY 173.A O no hydrogen 2.986 N/A VAL 178.A N TYR 174.A O no hydrogen 2.865 N/A LEU 179.A N VAL 175.A O no hydrogen 2.880 N/A TYR 180.A N LEU 176.A O no hydrogen 2.892 N/A TYR 180.A OH GLY 257.A O no hydrogen 2.567 N/A TYR 181.A N MET 177.A O no hydrogen 3.179 N/A LEU 182.A N VAL 178.A O no hydrogen 3.103 N/A ILE 183.A N LEU 179.A O no hydrogen 2.953 N/A HIS 184.A N TYR 180.A O no hydrogen 2.825 N/A VAL 185.A N TYR 181.A O no hydrogen 3.054 N/A ILE 186.A N TYR 181.A O no hydrogen 2.933 N/A VAL 190.A N LEU 182.A O no hydrogen 2.885 N/A PHE 191.A N LEU 182.A O no hydrogen 3.285 N/A ASN 193.A ND2 HIS 184.A NE2 no hydrogen 2.912 N/A ASN 193.A ND2 PHE 252.A O no hydrogen 3.016 N/A LEU 194.A N TYR 138.A OH no hydrogen 2.977 N/A LEU 195.A N ASN 193.A OD1 no hydrogen 3.022 N/A LEU 196.A N ASN 193.A OD1 no hydrogen 3.172 N/A SER 197.A OG ASP 213.A OD2 no hydrogen 3.425 N/A LEU 199.A N SER 197.A OG no hydrogen 3.258 N/A LYS 200.A N SER 197.A O no hydrogen 3.103 N/A LYS 200.A NZ ASP 209.A OD2 no hydrogen 2.762 N/A LYS 203.A N ASP 209.A OD1 no hydrogen 3.252 N/A VAL 205.A N PHE 208.A O no hydrogen 2.968 N/A PHE 208.A N VAL 205.A O no hydrogen 3.192 N/A VAL 210.A N LYS 203.A O no hydrogen 2.727 N/A GLY 211.A N ASP 209.A OD1 no hydrogen 3.150 N/A ASP 213.A N LEU 194.A O no hydrogen 2.974 N/A ASP 218.A N LYS 215.A O no hydrogen 3.238 N/A ILE 219.A N LEU 216.A O no hydrogen 3.102 N/A SER 222.A OG PRO 189.A O no hydrogen 3.480 N/A SER 222.A OG VAL 190.A O no hydrogen 2.989 N/A SER 222.A OG ASN 224.A O no hydrogen 3.500 N/A ASN 224.A N SER 222.A OG no hydrogen 2.977 N/A ASN 224.A ND2 PRO 188.A O no hydrogen 2.765 N/A SER 226.A N ASN 224.A OD1 no hydrogen 2.965 N/A SER 226.A OG ASN 224.A OD1 no hydrogen 2.718 N/A SER 227.A OG SER 3.A O no hydrogen 2.670 N/A SER 227.A OG THR 8.A OG1 no hydrogen 3.167 N/A GLY 229.A N THR 8.A OG1 no hydrogen 3.073 N/A SER 230.A N SER 227.A OG no hydrogen 3.240 N/A SER 230.A OG ASN 2.A O no hydrogen 3.429 N/A LEU 231.A N SER 227.A O no hydrogen 3.001 N/A LEU 232.A N LEU 228.A O no hydrogen 3.013 N/A HIS 233.A N GLY 229.A O no hydrogen 3.024 N/A GLY 234.A N SER 230.A O no hydrogen 3.023 N/A PHE 235.A N LEU 231.A O no hydrogen 3.075 N/A PHE 236.A N LEU 232.A O no hydrogen 3.026 N/A ARG 237.A N HIS 233.A O no hydrogen 3.154 N/A PHE 238.A N GLY 234.A O no hydrogen 2.957 N/A TYR 239.A N PHE 235.A O no hydrogen 3.257 N/A TYR 239.A OH MET 177.A O no hydrogen 2.684 N/A ALA 240.A N PHE 236.A O no hydrogen 2.852 N/A TYR 241.A N ARG 237.A O no hydrogen 2.927 N/A LYS 242.A N PHE 238.A O no hydrogen 2.925 N/A PHE 243.A N PHE 238.A O no hydrogen 2.757 N/A LYS 248.A N GLU 244.A O no hydrogen 3.054 N/A VAL 249.A N LEU 259.A O no hydrogen 2.976 N/A VAL 250.A N ALA 274.A O no hydrogen 2.890 N/A THR 251.A OG1 GLU 276.A OE1 no hydrogen 2.600 N/A ARG 253.A N THR 251.A OG1 no hydrogen 3.215 N/A ARG 253.A NE PRO 278.A O no hydrogen 2.834 N/A ARG 253.A NH2 ASP 209.A O no hydrogen 3.145 N/A ARG 253.A NH2 PRO 278.A O no hydrogen 2.696 N/A ARG 254.A NE ARG 253.A O no hydrogen 3.212 N/A ARG 254.A NH1 GLU 263.A OE2 no hydrogen 2.811 N/A GLY 257.A N ARG 254.A O no hydrogen 3.082 N/A TYR 258.A N ASP 256.A OD2 no hydrogen 3.258 N/A LYS 261.A N GLU 247.A O no hydrogen 3.188 N/A LYS 261.A NZ PRO 245.A O no hydrogen 2.818 N/A LYS 261.A NZ ARG 246.A O no hydrogen 3.086 N/A LYS 261.A NZ TYR 271.A O no hydrogen 2.757 N/A LYS 261.A NZ ILE 272.A O no hydrogen 3.099 N/A GLU 263.A N THR 260.A OG1 no hydrogen 3.223 N/A LYS 264.A N THR 260.A O no hydrogen 3.131 N/A LYS 264.A NZ ILE 281.A O no hydrogen 2.688 N/A GLY 265.A N LYS 261.A O no hydrogen 2.762 N/A TRP 266.A N LYS 261.A O no hydrogen 2.794 N/A ARG 270.A NE ARG 287.A O no hydrogen 3.203 N/A ILE 275.A N ASN 284.A OD1 no hydrogen 2.740 N/A GLU 276.A N VAL 250.A O no hydrogen 2.805 N/A ASP 277.A N HIS 283.A O no hydrogen 3.135 N/A PHE 279.A N ASP 277.A OD1 no hydrogen 3.304 N/A GLU 280.A N ASP 277.A OD1 no hydrogen 2.960 N/A HIS 283.A N GLU 280.A O no hydrogen 2.819 N/A ASN 284.A ND2 ARG 270.A O no hydrogen 3.139 N/A ASN 284.A ND2 LEU 273.A O no hydrogen 2.986 N/A VAL 285.A N ILE 275.A O no hydrogen 2.832 N/A GLY 286.A N ASN 284.A OD1 no hydrogen 2.916 N/A ARG 287.A N ASN 284.A O no hydrogen 3.235 N/A THR 288.A OG1 THR 168.A O no hydrogen 2.704 N/A VAL 289.A N GLY 286.A O no hydrogen 3.063 N/A SER 290.A N GLY 167.A O no hydrogen 3.008 N/A SER 290.A OG GLY 167.A O no hydrogen 3.388 N/A SER 290.A OG SER 292.A OG no hydrogen 3.269 N/A SER 292.A OG SER 290.A OG no hydrogen 3.269 N/A GLY 293.A N SER 290.A OG no hydrogen 3.204 N/A LEU 294.A N SER 290.A O no hydrogen 2.830 N/A TYR 295.A N SER 291.A O no hydrogen 3.055 N/A ARG 296.A N SER 292.A O no hydrogen 3.112 N/A ARG 296.A NH2 GLN 160.A O no hydrogen 2.716 N/A ILE 297.A N GLY 293.A O no hydrogen 2.978 N/A ARG 298.A N LEU 294.A O no hydrogen 2.925 N/A ARG 298.A NH1 TYR 239.A O no hydrogen 2.626 N/A GLY 299.A N TYR 295.A O no hydrogen 2.873 N/A GLU 300.A N ARG 296.A O no hydrogen 2.855 N/A PHE 301.A N ILE 297.A O no hydrogen 2.968 N/A MET 302.A N ARG 298.A O no hydrogen 2.907 N/A ALA 303.A N GLY 299.A O no hydrogen 3.160 N/A ALA 304.A N GLU 300.A O no hydrogen 3.020 N/A SER 305.A N PHE 301.A O no hydrogen 3.007 N/A SER 305.A OG PHE 301.A O no hydrogen 3.329 N/A ARG 306.A N MET 302.A O no hydrogen 2.964 N/A LEU 307.A N ALA 303.A O no hydrogen 2.998 N/A LEU 308.A N ALA 304.A O no hydrogen 3.188 N/A ASN 309.A N ARG 306.A O no hydrogen 3.091 N/A ASN 309.A ND2 HIS 233.A NE2 no hydrogen 3.198 N/A ASN 309.A ND2 SER 305.A O no hydrogen 2.919 N/A SER 310.A N LEU 307.A O no hydrogen 3.219 N/A SER 310.A OG ARG 306.A O no hydrogen 3.442 N/A SER 310.A OG LEU 307.A O no hydrogen 2.686 N/A TYR 317.A N ILE 315.A O no hydrogen 2.844 N/A SER 319.A N PRO 316.A O no hydrogen 3.080 N/A SER 319.A OG PRO 316.A O no hydrogen 2.699 N/A LEU 320.A N TYR 317.A O no hydrogen 3.182 N/A PHE 321.A N ASP 318.A O no hydrogen 3.019 N/A GLU 322.A N SER 319.A O no hydrogen 3.295 N/A ALA 324.A N ARG 158.A O no hydrogen 2.912 N/A