Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4e8w_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLN 5.A N PRO 2.A O no hydrogen 2.908 N/A GLN 5.A NE2 ALA 268.A O no hydrogen 2.873 N/A LEU 6.A N PRO 2.A O no hydrogen 3.357 N/A SER 9.A N LEU 6.A O no hydrogen 3.249 N/A SER 9.A OG THR 264.A O no hydrogen 2.471 N/A ARG 10.A N ASP 143.A OD2 no hydrogen 3.103 N/A ARG 10.A NE.A ASP 143.A OD2 no hydrogen 3.228 N/A ARG 10.A NE.B ASP 143.A OD1 no hydrogen 3.223 N/A ARG 10.A NE.B ASP 143.A OD2 no hydrogen 2.698 N/A ARG 10.A NH2.A ASP 143.A OD1 no hydrogen 2.501 N/A ARG 10.A NH2.B ASP 143.A OD1 no hydrogen 3.238 N/A VAL 11.A N GLN 64.A O no hydrogen 3.068 N/A LEU 12.A N VAL 144.A O no hydrogen 2.965 N/A VAL 13.A N GLY 66.A O no hydrogen 2.696 N/A VAL 14.A N LEU 146.A O no hydrogen 2.721 N/A GLY 15.A N LEU 68.A O no hydrogen 3.272 N/A ASP 16.A N SER 148.A O no hydrogen 3.180 N/A MET 18.A N GLY 49.A O no hydrogen 3.338 N/A LEU 19.A N THR 102.A O no hydrogen 2.942 N/A ASP 20.A N ARG 47.A O no hydrogen 3.018 N/A ARG 21.A N LYS 104.A O no hydrogen 3.050 N/A ARG 21.A NE GLU 46.A OE2 no hydrogen 3.073 N/A ARG 21.A NH1 GLU 75.A OE1 no hydrogen 3.253 N/A ARG 21.A NH2 GLU 46.A OE2 no hydrogen 3.085 N/A ARG 21.A NH2 GLU 75.A OE1 no hydrogen 3.396 N/A ARG 21.A NH2 GLU 75.A OE2 no hydrogen 2.852 N/A TYR 22.A N GLU 45.A O no hydrogen 2.885 N/A TRP 23.A N ARG 106.A O no hydrogen 2.704 N/A TRP 23.A NE1 GLN 44.A OE1 no hydrogen 3.112 N/A PHE 24.A N ARG 43.A O no hydrogen 3.026 N/A GLY 25.A N LEU 108.A O no hydrogen 2.857 N/A ASN 26.A N HIS 40.A O no hydrogen 2.774 N/A SER 31.A N VAL 36.A O no hydrogen 3.032 N/A GLU 33.A N SER 31.A OG no hydrogen 3.035 N/A VAL 38.A N ARG 29.A O no hydrogen 3.191 N/A HIS 40.A N ASN 26.A O no hydrogen 2.864 N/A GLN 42.A N PHE 24.A O no hydrogen 2.743 N/A GLN 42.A NE2 HIS 40.A O no hydrogen 3.214 N/A ARG 43.A N PHE 24.A O no hydrogen 3.268 N/A ARG 43.A NE GLU 45.A OE2 no hydrogen 3.320 N/A GLU 45.A N TYR 22.A O no hydrogen 3.079 N/A ARG 47.A N ASP 20.A O no hydrogen 3.048 N/A GLY 49.A N MET 18.A O no hydrogen 2.871 N/A ALA 51.A N ASP 16.A O no hydrogen 2.878 N/A ALA 52.A N GLY 49.A O no hydrogen 3.267 N/A ASN 53.A N GLY 50.A O no hydrogen 3.111 N/A ASN 53.A ND2 ASP 256.A OD2 no hydrogen 3.433 N/A ASN 53.A ND2 THR 290.A OG1 no hydrogen 3.163 N/A ALA 55.A N ALA 51.A O no hydrogen 3.001 N/A ARG 56.A N ALA 52.A O no hydrogen 3.037 N/A ASN 57.A N ASN 53.A O no hydrogen 3.300 N/A ASN 57.A N VAL 54.A O no hydrogen 3.337 N/A ASN 57.A ND2 ASN 53.A O no hydrogen 2.512 N/A THR 60.A OG1 ASN 57.A O no hydrogen 3.186 N/A THR 60.A OG1 VAL 293.A O no hydrogen 2.805 N/A GLY 62.A N VAL 59.A O no hydrogen 2.927 N/A GLY 63.A N ALA 58.A O no hydrogen 3.262 N/A GLN 64.A N SER 9.A O no hydrogen 2.921 N/A GLN 64.A NE2 ALA 7.A O no hydrogen 2.647 N/A GLY 66.A N VAL 11.A O no hydrogen 2.814 N/A LEU 67.A N THR 90.A O no hydrogen 2.941 N/A LEU 68.A N VAL 13.A O no hydrogen 2.858 N/A VAL 71.A N GLU 94.A O no hydrogen 2.997 N/A GLY 72.A N THR 101.A OG1 no hydrogen 2.878 N/A GLY 77.A N ASP 74.A OD1 no hydrogen 2.986 N/A GLU 78.A N ASP 74.A O no hydrogen 3.097 N/A ARG 79.A N GLU 75.A O no hydrogen 2.943 N/A ARG 79.A NE GLU 46.A OE1 no hydrogen 2.555 N/A ARG 79.A NH1 GLU 82.A OE1 no hydrogen 3.115 N/A ILE 80.A N PRO 76.A O no hydrogen 2.951 N/A VAL 81.A N GLY 77.A O no hydrogen 3.195 N/A GLU 82.A N GLU 78.A O no hydrogen 3.034 N/A LEU 83.A N ARG 79.A O no hydrogen 2.815 N/A LEU 84.A N ILE 80.A O no hydrogen 2.687 N/A GLY 85.A N VAL 81.A O no hydrogen 3.031 N/A SER 86.A N GLU 82.A O no hydrogen 3.236 N/A SER 86.A OG GLU 82.A O no hydrogen 3.341 N/A SER 86.A OG LEU 83.A O no hydrogen 3.424 N/A SER 87.A N LEU 84.A O no hydrogen 3.124 N/A SER 87.A OG LEU 83.A O no hydrogen 2.631 N/A SER 87.A OG LEU 84.A O no hydrogen 2.760 N/A THR 90.A N ALA 65.A O no hydrogen 2.970 N/A HIS 92.A N LEU 67.A O no hydrogen 2.796 N/A GLU 94.A N CYS 69.A O no hydrogen 2.805 N/A ASP 96.A N VAL 71.A O no hydrogen 3.047 N/A ALA 98.A N ASP 96.A OD1 no hydrogen 3.307 N/A LEU 99.A N ASP 96.A O no hydrogen 2.826 N/A THR 101.A N ASP 74.A OD2 no hydrogen 3.096 N/A THR 101.A OG1 ASP 74.A OD1 no hydrogen 2.717 N/A ILE 103.A N PHE 119.A O no hydrogen 3.097 N/A LYS 104.A N LEU 19.A O no hydrogen 3.018 N/A LEU 105.A N VAL 117.A O no hydrogen 2.763 N/A ARG 106.A N ARG 21.A O no hydrogen 2.915 N/A ARG 106.A NH1 ASP 20.A OD1 no hydrogen 3.053 N/A ARG 106.A NH1 LYS 104.A O no hydrogen 3.016 N/A VAL 107.A N LEU 115.A O no hydrogen 3.067 N/A LEU 108.A N TRP 23.A O no hydrogen 2.690 N/A ALA 109.A N GLN 112.A O no hydrogen 3.003 N/A LEU 114.A N VAL 107.A O no hydrogen 2.895 N/A ARG 116.A NH1 ASP 118.A OD2 no hydrogen 2.777 N/A VAL 117.A N LEU 105.A O no hydrogen 2.735 N/A PHE 119.A N ILE 103.A O no hydrogen 3.061 N/A THR 124.A N ASP 96.A OD2 no hydrogen 3.231 N/A THR 124.A OG1 ASP 96.A OD2 no hydrogen 3.440 N/A LEU 128.A N THR 124.A O no hydrogen 3.074 N/A LEU 129.A N HIS 125.A O no hydrogen 3.170 N/A ALA 130.A N GLU 126.A O no hydrogen 3.150 N/A GLY 131.A N VAL 127.A O no hydrogen 3.036 N/A LEU 132.A N LEU 128.A O no hydrogen 3.067 N/A ALA 133.A N LEU 129.A O no hydrogen 3.130 N/A ARG 134.A N ALA 130.A O no hydrogen 3.100 N/A PHE 135.A N GLY 131.A O no hydrogen 2.877 N/A ASP 136.A N LEU 132.A O no hydrogen 3.286 N/A VAL 137.A N ALA 133.A O no hydrogen 3.375 N/A LEU 138.A N ARG 134.A O no hydrogen 2.752 N/A LEU 139.A N PHE 135.A O no hydrogen 2.849 N/A GLN 141.A N LEU 138.A O no hydrogen 3.082 N/A HIS 142.A N LEU 139.A O no hydrogen 3.195 N/A HIS 142.A ND1 LEU 138.A O no hydrogen 2.661 N/A ASP 143.A N ARG 10.A O no hydrogen 2.885 N/A VAL 145.A N ALA 171.A O no hydrogen 3.033 N/A LEU 146.A N LEU 12.A O no hydrogen 2.875 N/A MET 147.A N LEU 173.A O no hydrogen 2.662 N/A SER 148.A N VAL 14.A O no hydrogen 2.728 N/A ASP 149.A N ASP 175.A O no hydrogen 3.285 N/A TYR 150.A N ASP 16.A OD2 no hydrogen 2.936 N/A ALA 151.A N ASP 149.A OD1 no hydrogen 2.902 N/A LYS 152.A N ASP 16.A OD2 no hydrogen 3.185 N/A LYS 152.A NZ TYR 150.A O no hydrogen 2.731 N/A GLY 154.A N ASP 16.A OD1 no hydrogen 2.750 N/A THR 156.A OG1 GLY 153.A O no hydrogen 2.600 N/A VAL 158.A N LEU 155.A O no hydrogen 3.374 N/A THR 159.A OG1 ARG 183.A O no hydrogen 2.807 N/A MET 161.A N HIS 157.A O no hydrogen 3.105 N/A ILE 162.A N VAL 158.A O no hydrogen 2.838 N/A GLU 163.A N THR 159.A O no hydrogen 3.165 N/A LYS 164.A N THR 160.A O no hydrogen 3.049 N/A LYS 164.A NZ ASP 136.A OD1 no hydrogen 3.257 N/A LYS 164.A NZ ASP 136.A OD2 no hydrogen 3.252 N/A ALA 165.A N MET 161.A O no hydrogen 2.984 N/A ARG 166.A N ILE 162.A O no hydrogen 2.933 N/A ARG 166.A NH1 ASP 224.A OD1 no hydrogen 3.550 N/A ARG 166.A NH2 ASP 224.A OD1 no hydrogen 3.499 N/A ARG 166.A NH2 ASP 224.A OD2 no hydrogen 3.205 N/A ALA 167.A N GLU 163.A O no hydrogen 3.261 N/A ALA 168.A N ALA 165.A O no hydrogen 3.101 N/A GLY 169.A N ARG 166.A O no hydrogen 3.172 N/A LYS 170.A N ALA 165.A O no hydrogen 3.040 N/A LYS 170.A NZ LEU 139.A O no hydrogen 3.070 N/A LYS 170.A NZ HIS 142.A O no hydrogen 3.163 N/A VAL 172.A N SER 188.A OG no hydrogen 2.909 N/A LEU 173.A N VAL 145.A O no hydrogen 2.932 N/A VAL 174.A N LEU 189.A O no hydrogen 2.929 N/A ASP 175.A N MET 147.A O no hydrogen 2.830 N/A TRP 181.A NE1 GLY 178.A O no hydrogen 2.878 N/A ARG 183.A NH2.A ASP 149.A OD2 no hydrogen 2.790 N/A TYR 184.A N TRP 181.A O no hydrogen 2.838 N/A TYR 184.A OH ASP 149.A OD2 no hydrogen 2.613 N/A ARG 185.A N ALA 182.A O no hydrogen 3.366 N/A GLY 186.A N LEU 221.A O no hydrogen 2.796 N/A ALA 187.A N TYR 184.A O no hydrogen 3.159 N/A SER 188.A N VAL 172.A O no hydrogen 2.999 N/A LEU 189.A N VAL 172.A O no hydrogen 3.325 N/A ILE 190.A N ALA 225.A O no hydrogen 3.090 N/A THR 191.A N VAL 174.A O no hydrogen 2.993 N/A THR 191.A OG1 VAL 174.A O no hydrogen 3.358 N/A THR 191.A OG1 ASP 175.A OD1 no hydrogen 3.568 N/A THR 191.A OG1 THR 191.A O no hydrogen 2.600 N/A ASN 193.A N GLU 196.A OE1 no hydrogen 2.792 N/A ARG 194.A NH1 GLU 232.A OE1 no hydrogen 3.286 N/A ARG 194.A NH2 GLU 232.A OE1 no hydrogen 3.359 N/A ARG 194.A NH2 GLU 232.A OE2 no hydrogen 3.134 N/A GLU 196.A N ASN 193.A OD1 no hydrogen 2.616 N/A LEU 197.A N ASN 193.A O no hydrogen 2.939 N/A ARG 198.A N ARG 194.A O no hydrogen 3.305 N/A VAL 201.A N LEU 197.A O no hydrogen 3.008 N/A GLY 202.A N ARG 198.A O no hydrogen 2.277 N/A TRP 204.A N GLN 203.A OE1 no hydrogen 2.537 N/A LYS 205.A N ASP 209.A OD2 no hydrogen 3.114 N/A ASP 209.A N SER 206.A O no hydrogen 2.480 N/A ASP 209.A N SER 206.A OG no hydrogen 2.999 N/A LEU 210.A N SER 206.A O no hydrogen 2.793 N/A ARG 211.A N GLU 207.A O no hydrogen 3.040 N/A ARG 211.A NH1 GLU 243.A OE2 no hydrogen 3.493 N/A ALA 212.A N ASP 208.A O no hydrogen 3.359 N/A ARG 213.A N ASP 209.A O no hydrogen 2.902 N/A ARG 213.A NE VAL 201.A O no hydrogen 2.862 N/A VAL 214.A N LEU 210.A O no hydrogen 2.997 N/A ALA 215.A N ARG 211.A O no hydrogen 3.135 N/A ASN 216.A N ALA 212.A O no hydrogen 3.246 N/A ARG 218.A N VAL 214.A O no hydrogen 2.939 N/A ARG 218.A NE ASP 224.A O no hydrogen 3.192 N/A ARG 218.A NH2 ASP 224.A O no hydrogen 3.533 N/A ALA 219.A N ALA 215.A O no hydrogen 3.113 N/A GLU 220.A N ASN 216.A O no hydrogen 2.915 N/A ILE 223.A N ARG 218.A O no hydrogen 3.262 N/A ASP 224.A N ALA 187.A O no hydrogen 3.226 N/A ALA 225.A N SER 188.A O no hydrogen 2.899 N/A LEU 226.A N PHE 238.A O no hydrogen 3.160 N/A LEU 227.A N ILE 190.A O no hydrogen 2.898 N/A LEU 228.A N THR 236.A O no hydrogen 2.893 N/A THR 229.A N PRO 192.A O no hydrogen 3.206 N/A THR 229.A OG1 PRO 192.A O no hydrogen 3.250 N/A ARG 230.A N GLY 234.A O no hydrogen 2.677 N/A ARG 230.A NH1 THR 236.A OG1 no hydrogen 2.444 N/A GLU 233.A N ARG 230.A O no hydrogen 3.255 N/A GLY 234.A N SER 231.A O no hydrogen 2.567 N/A MET 235.A N ALA 246.A O no hydrogen 2.932 N/A THR 236.A N LEU 228.A O no hydrogen 2.898 N/A THR 236.A OG1 HIS 245.A ND1 no hydrogen 3.342 N/A LEU 237.A N LEU 244.A O no hydrogen 2.853 N/A PHE 238.A N LEU 226.A O no hydrogen 2.835 N/A SER 239.A N GLY 242.A O no hydrogen 3.012 N/A GLY 242.A N SER 239.A O no hydrogen 2.554 N/A LEU 244.A N LEU 237.A O no hydrogen 3.170 N/A ALA 246.A N MET 235.A O no hydrogen 3.114 N/A THR 257.A N GLY 253.A O no hydrogen 3.291 N/A THR 257.A OG1 ASN 57.A OD1 no hydrogen 2.940 N/A THR 257.A OG1 GLY 253.A O no hydrogen 2.819 N/A VAL 258.A N ALA 254.A O no hydrogen 2.968 N/A ILE 259.A N GLY 255.A O no hydrogen 3.421 N/A ALA 260.A N ASP 256.A O no hydrogen 3.187 N/A THR 261.A N THR 257.A O no hydrogen 3.063 N/A THR 261.A OG1 THR 257.A O no hydrogen 2.614 N/A VAL 262.A N VAL 258.A O no hydrogen 3.079 N/A ALA 263.A N ILE 259.A O no hydrogen 3.080 N/A THR 264.A N ALA 260.A O no hydrogen 2.898 N/A MET 265.A N THR 261.A O no hydrogen 2.985 N/A LEU 266.A N VAL 262.A O no hydrogen 3.039 N/A GLY 267.A N ALA 263.A O no hydrogen 3.138 N/A ALA 268.A N THR 264.A O no hydrogen 3.248 N/A ALA 268.A N MET 265.A O no hydrogen 2.705 N/A GLY 269.A N LEU 266.A O no hydrogen 3.005 N/A VAL 270.A N MET 265.A O no hydrogen 3.339 N/A ALA 275.A N PRO 271.A O no hydrogen 3.020 N/A VAL 276.A N LEU 272.A O no hydrogen 2.838 N/A VAL 277.A N VAL 273.A O no hydrogen 2.958 N/A LEU 278.A N ASP 274.A O no hydrogen 3.002 N/A ALA 279.A N ALA 275.A O no hydrogen 3.124 N/A ASN 280.A N VAL 276.A O no hydrogen 3.254 N/A ASN 280.A N VAL 277.A O no hydrogen 3.015 N/A ASN 280.A ND2 PRO 247.A O no hydrogen 2.251 N/A ALA 282.A N LEU 278.A O no hydrogen 3.038 N/A ALA 283.A N ALA 279.A O no hydrogen 3.123 N/A GLY 284.A N ASN 280.A O no hydrogen 2.868 N/A ILE 285.A N ALA 282.A O no hydrogen 3.400 N/A VAL 286.A N ALA 282.A O no hydrogen 3.370 N/A GLY 288.A N ILE 285.A O no hydrogen 2.605 N/A LYS 289.A NZ GLU 297.A OE1 no hydrogen 3.503 N/A ASP 294.A N GLU 297.A OE2 no hydrogen 2.667 N/A TYR 295.A OH VAL 1.A O no hydrogen 2.553 N/A LEU 298.A N ASP 294.A O no hydrogen 3.463 N/A