Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4ear_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 3.A N ASP 6.A OD2 no hydrogen 2.679 N/A THR 3.A OG1 ASP 6.A OD2 no hydrogen 2.998 N/A ASP 6.A N THR 3.A OG1 no hydrogen 3.099 N/A TYR 7.A N THR 3.A O no hydrogen 3.441 N/A LYS 8.A N TYR 4.A O no hydrogen 3.063 N/A ASN 9.A N GLU 5.A O no hydrogen 2.664 N/A THR 10.A N ASP 6.A O no hydrogen 3.164 N/A THR 10.A OG1 ASP 6.A O no hydrogen 3.291 N/A THR 10.A OG1 PRO 51.A O no hydrogen 2.666 N/A ALA 11.A N TYR 7.A O no hydrogen 2.966 N/A GLU 12.A N LYS 8.A O no hydrogen 2.770 N/A TYR 13.A N ASN 9.A O no hydrogen 2.926 N/A LEU 14.A N THR 10.A O no hydrogen 3.082 N/A LEU 15.A N ALA 11.A O no hydrogen 2.905 N/A SER 16.A N GLU 12.A O no hydrogen 2.960 N/A SER 16.A OG.A GLU 12.A O no hydrogen 3.153 N/A SER 16.A OG.B GLU 12.A O no hydrogen 3.033 N/A SER 16.A OG.B TYR 13.A O no hydrogen 3.005 N/A SER 16.A OG.B HIS 17.A ND1 no hydrogen 3.078 N/A HIS 17.A N TYR 13.A O no hydrogen 3.119 N/A HIS 17.A N LEU 14.A O no hydrogen 3.079 N/A HIS 17.A ND1 TYR 13.A O no hydrogen 2.800 N/A HIS 17.A ND1 SER 16.A OG.B no hydrogen 3.078 N/A THR 18.A OG1 GLN 43.A OE1 no hydrogen 2.598 N/A HIS 20.A N THR 18.A OG1 no hydrogen 3.249 N/A ARG 21.A NH1 THR 18.A O no hydrogen 2.836 N/A ARG 21.A NH1 HIS 20.A O no hydrogen 2.805 N/A ARG 21.A NH2 LEU 15.A O no hydrogen 3.065 N/A GLN 23.A N ALA 74.A O no hydrogen 2.827 N/A GLN 23.A NE2 ASP 106.A OD1 no hydrogen 3.004 N/A GLN 23.A NE2 ASP 106.A OD2 no hydrogen 3.398 N/A GLN 23.A NE2 PRO 279.A O no hydrogen 2.882 N/A VAL 24.A N ALA 74.A O no hydrogen 3.252 N/A ALA 25.A N THR 107.A O no hydrogen 2.919 N/A ILE 26.A N VAL 76.A O no hydrogen 2.848 N/A ILE 27.A N VAL 109.A O no hydrogen 2.891 N/A CYS 28.A N MET 78.A O no hydrogen 2.865 N/A GLY 29.A N THR 111.A OG1 no hydrogen 3.064 N/A SER 30.A OG HIS 61.A NE2 no hydrogen 2.777 N/A GLY 31.A N GLY 60.A O no hydrogen 3.457 N/A LEU 32.A N GLY 29.A O no hydrogen 2.988 N/A LEU 35.A N LEU 32.A O no hydrogen 3.110 N/A THR 36.A N GLY 33.A O no hydrogen 3.213 N/A THR 36.A OG1 GLY 33.A O no hydrogen 2.855 N/A ASP 37.A N GLY 34.A O no hydrogen 2.966 N/A LEU 39.A N THR 36.A O no hydrogen 3.011 N/A THR 40.A N PHE 69.A O no hydrogen 2.824 N/A THR 40.A OG1 PHE 69.A O no hydrogen 3.343 N/A GLN 43.A N PHE 67.A O no hydrogen 2.759 N/A GLN 43.A NE2 HIS 17.A O no hydrogen 2.965 N/A PHE 45.A N LEU 65.A O no hydrogen 2.735 N/A ASP 46.A N GLU 49.A OE2 no hydrogen 2.942 N/A TYR 47.A N GLY 63.A O no hydrogen 2.908 N/A TYR 47.A OH ARG 64.A O no hydrogen 3.377 N/A TYR 47.A OH GLY 80.A O no hydrogen 2.599 N/A GLU 49.A N ASP 46.A O no hydrogen 2.974 N/A ILE 50.A N TYR 47.A O no hydrogen 3.068 N/A ASN 52.A ND2 ASP 6.A O no hydrogen 3.232 N/A ASN 52.A ND2 THR 10.A OG1 no hydrogen 3.049 N/A PHE 53.A N ILE 50.A O no hydrogen 3.151 N/A ARG 55.A N TYR 88.A OH no hydrogen 3.040 N/A SER 56.A OG ARG 81.A O no hydrogen 3.147 N/A THR 57.A N GLU 86.A OE2 no hydrogen 2.873 N/A THR 57.A OG1 GLU 86.A OE2 no hydrogen 2.478 N/A HIS 61.A N VAL 58.A O no hydrogen 3.087 N/A HIS 61.A NE2 SER 30.A OG no hydrogen 2.777 N/A GLY 63.A N GLN 79.A O no hydrogen 2.802 N/A ARG 64.A N GLN 79.A O no hydrogen 3.285 N/A LEU 65.A N PHE 45.A O no hydrogen 2.638 N/A VAL 66.A N MET 77.A O no hydrogen 2.878 N/A PHE 67.A N GLN 43.A O no hydrogen 2.921 N/A GLY 68.A N CYS 75.A O no hydrogen 3.140 N/A PHE 69.A N THR 40.A O no hydrogen 2.948 N/A LEU 70.A N ARG 73.A O no hydrogen 2.762 N/A ASN 71.A ND2 SER 272.A O no hydrogen 2.965 N/A ARG 73.A N LEU 70.A O no hydrogen 2.932 N/A ARG 73.A NH1 GLN 23.A OE1 no hydrogen 2.886 N/A ARG 73.A NH1 ILE 278.A O no hydrogen 2.857 N/A ARG 73.A NH2 ILE 278.A O no hydrogen 2.653 N/A CYS 75.A N GLY 68.A O no hydrogen 2.870 N/A CYS 75.A SG ARG 73.A O no hydrogen 3.496 N/A VAL 76.A N VAL 24.A O no hydrogen 2.879 N/A MET 77.A N VAL 66.A O no hydrogen 2.790 N/A MET 78.A N ILE 26.A O no hydrogen 2.835 N/A GLN 79.A N ARG 64.A O no hydrogen 2.810 N/A GLN 79.A NE2 GLY 33.A O no hydrogen 3.136 N/A ARG 81.A N HIS 61.A ND1 no hydrogen 3.047 N/A ARG 81.A NE GLU 221.A OE2 no hydrogen 2.883 N/A ARG 81.A NH1 THR 111.A O no hydrogen 3.029 N/A ARG 81.A NH1 GLU 221.A OE1 no hydrogen 2.776 N/A ARG 81.A NH2 THR 111.A O no hydrogen 2.806 N/A HIS 83.A N GLU 86.A OE1 no hydrogen 2.889 N/A HIS 83.A ND1 GLU 86.A OE1 no hydrogen 2.920 N/A GLU 86.A N HIS 83.A O no hydrogen 3.055 N/A GLY 87.A N MET 84.A O no hydrogen 2.914 N/A TYR 88.A OH ARG 55.A O no hydrogen 2.566 N/A LYS 92.A N PRO 89.A O no hydrogen 2.927 N/A VAL 93.A N PRO 89.A O no hydrogen 3.131 N/A THR 94.A N LEU 90.A O no hydrogen 2.989 N/A THR 94.A OG1 LEU 90.A O no hydrogen 2.797 N/A PHE 95.A N LYS 92.A O no hydrogen 3.214 N/A VAL 97.A N THR 94.A O no hydrogen 2.944 N/A ARG 98.A NH1 HIS 227.A ND1 no hydrogen 3.395 N/A ARG 98.A NH2 TYR 7.A OH no hydrogen 3.186 N/A VAL 99.A N PHE 95.A O no hydrogen 3.392 N/A PHE 100.A N PRO 96.A O no hydrogen 2.776 N/A HIS 101.A N VAL 97.A O no hydrogen 3.148 N/A LEU 102.A N ARG 98.A O no hydrogen 3.095 N/A LEU 103.A N VAL 99.A O no hydrogen 2.901 N/A GLY 104.A N HIS 101.A O no hydrogen 2.989 N/A VAL 105.A N PHE 100.A O no hydrogen 3.076 N/A ASP 106.A N GLN 23.A O no hydrogen 2.821 N/A THR 107.A OG1 ASP 106.A OD1 no hydrogen 2.709 N/A LEU 108.A N ARG 231.A O no hydrogen 2.765 N/A VAL 109.A N ALA 25.A O no hydrogen 2.839 N/A VAL 110.A N PHE 233.A O no hydrogen 2.797 N/A THR 111.A N ILE 27.A O no hydrogen 3.016 N/A THR 111.A OG1 ILE 27.A O no hydrogen 2.662 N/A ASN 112.A N PHE 235.A O no hydrogen 3.188 N/A ASN 112.A ND2 THR 218.A OG1 no hydrogen 2.759 N/A ALA 114.A N LEU 237.A O no hydrogen 2.945 N/A GLY 115.A N VAL 214.A O no hydrogen 2.915 N/A GLY 116.A N ASN 240.A O no hydrogen 2.811 N/A LEU 117.A N ASP 212.A O no hydrogen 2.840 N/A ASN 118.A N ASP 212.A O no hydrogen 3.055 N/A ASN 118.A ND2 ASP 212.A OD1 no hydrogen 3.092 N/A LYS 120.A N ASN 118.A OD1 no hydrogen 2.860 N/A PHE 121.A N ASN 118.A O no hydrogen 2.990 N/A GLU 122.A N ASP 125.A OD2 no hydrogen 2.936 N/A GLY 124.A N ILE 238.A O no hydrogen 2.745 N/A ASP 125.A N GLU 122.A O no hydrogen 3.036 N/A MET 127.A N SER 236.A O no hydrogen 2.799 N/A LEU 128.A N GLN 185.A O no hydrogen 2.765 N/A ILE 129.A N GLY 234.A O no hydrogen 2.955 N/A ARG 130.A N GLY 187.A O no hydrogen 2.901 N/A ARG 130.A NH2.B GLU 186.A OE1 no hydrogen 2.719 N/A HIS 132.A N ASP 131.A OD1 no hydrogen 2.854 N/A HIS 132.A ND1 TYR 163.A OH no hydrogen 2.813 N/A ILE 133.A N TYR 189.A O no hydrogen 2.968 N/A GLY 137.A N ASN 134.A OD1 no hydrogen 3.020 N/A PHE 138.A N ASN 134.A O no hydrogen 3.190 N/A SER 139.A N PRO 136.A O no hydrogen 3.090 N/A SER 139.A OG.B PRO 136.A O no hydrogen 2.955 N/A GLY 140.A N GLY 137.A O no hydrogen 3.188 N/A GLN 141.A N PRO 136.A O no hydrogen 2.962 N/A ASN 142.A N GLY 140.A O no hydrogen 3.022 N/A LEU 144.A N ASN 142.A OD1 no hydrogen 2.844 N/A ARG 145.A N ASN 142.A O no hydrogen 3.101 N/A ARG 145.A NH1.B GLY 140.A O no hydrogen 2.768 N/A ASN 148.A ND2 GLY 153.A O no hydrogen 2.864 N/A ARG 151.A N ASP 149.A OD1 no hydrogen 2.878 N/A ARG 151.A NE ASP 149.A OD1 no hydrogen 3.018 N/A ARG 151.A NE ASP 149.A OD2 no hydrogen 3.336 N/A ARG 151.A NH1 ASP 149.A OD2 no hydrogen 2.784 N/A PHE 152.A N ASP 149.A O no hydrogen 2.858 N/A GLY 153.A N ASP 149.A O no hydrogen 3.180 N/A ARG 155.A NE ARG 155.A O no hydrogen 3.049 N/A ARG 155.A NH1 GLY 146.A O no hydrogen 2.799 N/A ARG 155.A NH2 GLY 146.A O no hydrogen 2.925 N/A PHE 156.A N ASP 154.A OD1 no hydrogen 2.834 N/A ALA 162.A N MET 159.A O no hydrogen 3.148 N/A TYR 163.A OH HIS 132.A ND1 no hydrogen 2.813 N/A ASP 164.A N VAL 232.A O no hydrogen 2.872 N/A MET 167.A N ASP 164.A OD2 no hydrogen 2.976 N/A ARG 168.A N ASP 164.A O no hydrogen 3.275 N/A ARG 168.A NH1 GLU 186.A OE2 no hydrogen 3.334 N/A ARG 168.A NH2 TYR 163.A O no hydrogen 3.062 N/A GLN 169.A N ARG 165.A O no hydrogen 2.997 N/A ARG 170.A N THR 166.A O no hydrogen 3.070 N/A ALA 171.A N MET 167.A O no hydrogen 2.987 N/A LEU 172.A N ARG 168.A O no hydrogen 2.927 N/A SER 173.A N GLN 169.A O no hydrogen 2.782 N/A SER 173.A OG GLN 169.A O no hydrogen 2.908 N/A THR 174.A N ARG 170.A O no hydrogen 2.950 N/A THR 174.A OG1 ARG 170.A O no hydrogen 2.990 N/A TYR 175.A N ALA 171.A O no hydrogen 3.254 N/A LYS 176.A N LEU 172.A O no hydrogen 3.109 N/A LYS 176.A N SER 173.A O no hydrogen 3.059 N/A GLN 177.A N SER 173.A O no hydrogen 3.179 N/A ARG 182.A NE ASP 125.A OD1 no hydrogen 3.059 N/A ARG 182.A NH2 LYS 120.A O no hydrogen 2.997 N/A ARG 182.A NH2 ASP 125.A OD2 no hydrogen 2.741 N/A LEU 184.A N GLU 183.A OE1 no hydrogen 3.048 N/A GLN 185.A N ILE 126.A O no hydrogen 3.053 N/A GLY 187.A N LEU 128.A O no hydrogen 2.903 N/A THR 188.A N ASP 212.A OD2 no hydrogen 2.719 N/A TYR 189.A N ASP 131.A O no hydrogen 3.024 N/A TYR 189.A OH SER 217.A O no hydrogen 3.207 N/A VAL 190.A N ALA 213.A O no hydrogen 2.952 N/A MET 191.A N ILE 133.A O no hydrogen 3.168 N/A VAL 192.A N GLY 215.A O no hydrogen 2.912 N/A THR 199.A N GLU 202.A OE1 no hydrogen 2.895 N/A GLU 202.A N THR 199.A OG1 no hydrogen 3.019 N/A CYS 203.A N THR 199.A O no hydrogen 2.900 N/A ARG 204.A N VAL 200.A O no hydrogen 2.956 N/A ARG 204.A NH2 MET 244.A O no hydrogen 2.995 N/A VAL 205.A N ALA 201.A O no hydrogen 2.966 N/A LEU 206.A N GLU 202.A O no hydrogen 2.988 N/A GLN 207.A N CYS 203.A O no hydrogen 3.004 N/A LYS 208.A N ARG 204.A O no hydrogen 2.945 N/A LEU 209.A N VAL 205.A O no hydrogen 2.913 N/A GLY 210.A N GLN 207.A O no hydrogen 2.928 N/A ALA 211.A N LEU 206.A O no hydrogen 3.119 N/A ASP 212.A N THR 188.A O no hydrogen 2.865 N/A ALA 213.A N THR 188.A O no hydrogen 3.202 N/A VAL 214.A N GLY 115.A O no hydrogen 2.944 N/A GLY 215.A N VAL 190.A O no hydrogen 3.052 N/A SER 217.A N TYR 189.A OH no hydrogen 3.136 N/A SER 217.A OG THR 218.A OG1 no hydrogen 2.829 N/A THR 218.A OG1 SER 217.A OG no hydrogen 2.829 N/A VAL 219.A N SER 217.A O no hydrogen 2.881 N/A VAL 222.A N THR 218.A O no hydrogen 2.968 N/A ILE 223.A N VAL 219.A O no hydrogen 3.036 N/A VAL 224.A N PRO 220.A O no hydrogen 3.019 N/A ALA 225.A N GLU 221.A O no hydrogen 2.917 N/A ARG 226.A N VAL 222.A O no hydrogen 2.878 N/A ARG 226.A NH1 LEU 230.A O no hydrogen 2.757 N/A HIS 227.A N ILE 223.A O no hydrogen 2.965 N/A HIS 227.A NE2 ASN 148.A OD1 no hydrogen 2.843 N/A CYS 228.A N VAL 224.A O no hydrogen 3.115 N/A CYS 228.A SG.A VAL 224.A O no hydrogen 3.527 N/A CYS 228.A SG.A ALA 225.A O no hydrogen 3.697 N/A CYS 228.A SG.B VAL 224.A O no hydrogen 3.818 N/A GLY 229.A N ARG 226.A O no hydrogen 3.051 N/A LEU 230.A N ALA 225.A O no hydrogen 2.859 N/A ARG 231.A N ASP 106.A O no hydrogen 3.018 N/A ARG 231.A NH1 THR 107.A OG1 no hydrogen 2.922 N/A PHE 233.A N LEU 108.A O no hydrogen 2.945 N/A PHE 235.A N VAL 110.A O no hydrogen 3.071 N/A SER 236.A N MET 127.A O no hydrogen 2.810 N/A SER 236.A OG ASN 112.A OD1 no hydrogen 2.681 N/A LEU 237.A N ASN 112.A O no hydrogen 2.778 N/A ILE 238.A N ASP 125.A O no hydrogen 2.881 N/A THR 239.A N ALA 114.A O no hydrogen 3.044 N/A THR 239.A OG1 ALA 114.A O no hydrogen 3.303 N/A THR 239.A OG1 ASN 240.A OD1 no hydrogen 2.800 N/A LYS 241.A NZ GLU 122.A OE1 no hydrogen 3.434 N/A LYS 241.A NZ GLU 122.A OE2 no hydrogen 3.180 N/A VAL 242.A N GLY 116.A O no hydrogen 2.987 N/A SER 248.A N ASP 245.A OD2 no hydrogen 3.012 N/A GLU 250.A N SER 248.A OG no hydrogen 3.054 N/A ASN 253.A ND2 LYS 251.A O no hydrogen 3.058 N/A GLU 255.A N ASN 253.A OD1 no hydrogen 2.888 N/A VAL 256.A N ASN 253.A O no hydrogen 3.374 N/A ALA 258.A N GLU 254.A O no hydrogen 2.922 N/A ALA 259.A N GLU 255.A O no hydrogen 3.051 N/A GLY 260.A N VAL 256.A O no hydrogen 3.368 N/A LYS 261.A N LEU 257.A O no hydrogen 3.133 N/A GLN 262.A N ALA 258.A O no hydrogen 3.101 N/A ALA 263.A N ALA 259.A O no hydrogen 3.080 N/A ALA 264.A N LYS 261.A O no hydrogen 3.270 N/A LYS 266.A NZ GLY 124.A O no hydrogen 2.760 N/A LEU 267.A N ALA 263.A O no hydrogen 2.878 N/A GLU 268.A N ALA 264.A O no hydrogen 3.008 N/A GLN 269.A N GLN 265.A O no hydrogen 3.089 N/A PHE 270.A N LYS 266.A O no hydrogen 2.976 N/A VAL 271.A N LEU 267.A O no hydrogen 2.882 N/A SER 272.A N GLU 268.A O no hydrogen 3.180 N/A ILE 273.A N GLN 269.A O no hydrogen 3.125 N/A LEU 274.A N PHE 270.A O no hydrogen 2.944 N/A MET 275.A N VAL 271.A O no hydrogen 2.989 N/A ALA 276.A N SER 272.A O no hydrogen 3.424 N/A SER 277.A N LEU 274.A O no hydrogen 2.849 N/A SER 277.A OG LEU 274.A O no hydrogen 2.615 N/A ILE 278.A N MET 275.A O no hydrogen 3.012 N/A