Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4eb6_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 1.A N GLU 3.A OE1 no hydrogen 2.701 N/A MET 1.A N THR 123.A OG1 no hydrogen 2.533 N/A CYS 4.A N THR 44.A O no hydrogen 2.929 N/A CYS 4.A SG GLU 3.A O no hydrogen 3.262 N/A CYS 4.A SG GLN 126.A OE1.A no hydrogen 3.574 N/A ILE 5.A N GLY 127.A O no hydrogen 3.382 N/A SER 6.A N ARG 57.A O no hydrogen 3.452 N/A ILE 7.A N LEU 129.A O no hydrogen 2.785 N/A HIS 8.A N VAL 59.A O no hydrogen 2.848 N/A VAL 9.A N PHE 131.A O no hydrogen 2.861 N/A GLY 10.A N VAL 61.A O no hydrogen 3.130 N/A GLN 11.A NE2 GLN 15.A OE1 no hydrogen 2.975 N/A VAL 14.A N GLY 10.A O no hydrogen 3.268 N/A GLN 15.A N GLN 11.A O no hydrogen 2.952 N/A ILE 16.A N ALA 12.A O no hydrogen 2.751 N/A GLY 17.A N VAL 14.A O no hydrogen 2.901 N/A ASN 18.A N VAL 14.A O no hydrogen 2.971 N/A ASN 18.A ND2 ASN 18.A O no hydrogen 2.774 N/A CYS 20.A N ILE 16.A O no hydrogen 3.260 N/A CYS 20.A SG ILE 16.A O no hydrogen 3.354 N/A TRP 21.A N GLY 17.A O no hydrogen 3.110 N/A LEU 23.A N ALA 19.A O no hydrogen 3.449 N/A TYR 24.A N TRP 21.A O no hydrogen 3.375 N/A CYS 25.A N GLU 22.A O no hydrogen 3.128 N/A CYS 25.A SG TRP 21.A O no hydrogen 3.247 N/A LEU 26.A N GLU 22.A O no hydrogen 3.361 N/A GLY 29.A N CYS 25.A O no hydrogen 2.908 N/A GLN 31.A N GLN 35.A O no hydrogen 3.085 N/A GLY 34.A N GLN 31.A O no hydrogen 2.839 N/A GLN 35.A NE2 GLN 35.A O no hydrogen 3.667 N/A SER 41.A OG ASP 39.A O no hydrogen 2.939 N/A ASN 43.A ND2 ASP 40.A O no hydrogen 2.764 N/A THR 44.A N SER 41.A O no hydrogen 3.372 N/A THR 44.A OG1 SER 41.A O no hydrogen 2.643 N/A THR 44.A OG1 LEU 235.A O no hydrogen 2.635 N/A PHE 45.A N PHE 42.A O no hydrogen 3.148 N/A PHE 46.A N PHE 42.A O no hydrogen 3.174 N/A SER 47.A N VAL 55.A O no hydrogen 2.806 N/A SER 47.A OG VAL 55.A O no hydrogen 3.055 N/A THR 49.A N LYS 53.A O no hydrogen 3.125 N/A THR 49.A OG1 LYS 53.A O no hydrogen 2.724 N/A GLY 52.A N THR 49.A OG1 no hydrogen 3.288 N/A LYS 53.A NZ GLN 78.A O no hydrogen 3.117 N/A HIS 54.A N GLY 34.A O no hydrogen 2.811 N/A VAL 55.A N SER 47.A O no hydrogen 3.029 N/A ARG 57.A N PHE 45.A O no hydrogen 2.941 N/A ARG 57.A NE ASN 43.A O no hydrogen 3.064 N/A ARG 57.A NH2 ASN 43.A O no hydrogen 2.683 N/A VAL 59.A N SER 6.A O no hydrogen 2.937 N/A VAL 61.A N HIS 8.A O no hydrogen 2.792 N/A ASP 62.A N ILE 86.A O no hydrogen 3.354 N/A ILE 68.A N PRO 65.A O no hydrogen 3.020 N/A ASP 69.A N PRO 65.A O no hydrogen 2.978 N/A GLU 70.A N THR 66.A O no hydrogen 3.198 N/A VAL 71.A N ILE 68.A O no hydrogen 3.129 N/A ARG 72.A N ILE 68.A O no hydrogen 3.111 N/A ARG 72.A NE ASP 69.A OD1 no hydrogen 3.296 N/A ARG 72.A NH2 ASP 69.A OD1 no hydrogen 3.162 N/A ARG 72.A NH2 THR 87.A OG1 no hydrogen 2.787 N/A THR 73.A N ASP 69.A O no hydrogen 2.958 N/A THR 73.A OG1 ASP 69.A O no hydrogen 2.740 N/A THR 73.A OG1 GLU 70.A O no hydrogen 3.173 N/A GLY 74.A N VAL 71.A O no hydrogen 3.206 N/A ARG 77.A N GLY 74.A O no hydrogen 3.256 N/A GLN 84.A N HIS 81.A O no hydrogen 2.759 N/A LEU 85.A N GLN 84.A OE1 no hydrogen 2.580 N/A ILE 86.A N PHE 60.A O no hydrogen 2.830 N/A GLY 88.A N ASP 62.A O no hydrogen 3.260 N/A ALA 93.A N ASP 91.A OD1 no hydrogen 3.047 N/A ASN 95.A N ALA 92.A O no hydrogen 2.949 N/A TYR 96.A OH THR 186.A OG1 no hydrogen 2.986 N/A ARG 98.A NE ASP 91.A O no hydrogen 3.343 N/A ARG 98.A NH1 GLU 404.A OE2 no hydrogen 3.186 N/A ARG 98.A NH2 GLU 90.A OE1 no hydrogen 3.198 N/A GLY 99.A N ASN 95.A O no hydrogen 3.322 N/A HIS 100.A N TYR 96.A O no hydrogen 2.759 N/A TYR 101.A N ALA 97.A O no hydrogen 2.803 N/A TYR 101.A OH GLU 410.A OE2 no hydrogen 2.638 N/A THR 102.A N ALA 97.A O no hydrogen 3.324 N/A LYS 105.A N THR 102.A O no hydrogen 3.252 N/A ILE 107.A N GLY 104.A O no hydrogen 3.097 N/A ILE 108.A N GLY 104.A O no hydrogen 2.870 N/A VAL 111.A N ILE 107.A O no hydrogen 3.024 N/A LEU 112.A N ILE 108.A O no hydrogen 3.125 N/A ASP 113.A N ASP 109.A O no hydrogen 3.187 N/A ARG 114.A N VAL 111.A O no hydrogen 3.142 N/A ARG 114.A NE ARG 114.A O no hydrogen 3.335 N/A ILE 115.A N VAL 111.A O no hydrogen 2.904 N/A ARG 116.A N LEU 112.A O no hydrogen 3.358 N/A ARG 116.A NH1 TYR 154.A OH no hydrogen 3.164 N/A LYS 117.A NZ ASP 113.A O no hydrogen 2.935 N/A LYS 117.A NZ ASP 113.A OD2 no hydrogen 3.371 N/A ALA 119.A N ILE 115.A O no hydrogen 2.914 N/A ASP 120.A N ARG 116.A O no hydrogen 3.076 N/A CYS 122.A N ALA 119.A O no hydrogen 3.279 N/A CYS 122.A SG GLU 3.A OE2 no hydrogen 3.269 N/A CYS 122.A SG LEU 118.A O no hydrogen 3.422 N/A GLN 126.A N ARG 2.A O no hydrogen 2.801 N/A PHE 128.A N SER 158.A O no hydrogen 3.266 N/A LEU 129.A N ILE 5.A O no hydrogen 2.757 N/A VAL 130.A N LEU 160.A O no hydrogen 2.921 N/A PHE 131.A N ILE 7.A O no hydrogen 2.700 N/A HIS 132.A N PHE 162.A O no hydrogen 3.204 N/A PHE 134.A N ILE 164.A O no hydrogen 3.003 N/A SER 140.A OG PHE 134.A O no hydrogen 3.102 N/A SER 140.A OG GLY 136.A O no hydrogen 2.316 N/A SER 140.A OG SER 140.A O no hydrogen 2.529 N/A THR 143.A OG1 GLY 139.A O no hydrogen 2.696 N/A SER 144.A OG THR 183.A O no hydrogen 3.543 N/A SER 144.A OG THR 186.A OG1 no hydrogen 2.698 N/A LEU 145.A N GLY 141.A O no hydrogen 3.268 N/A LEU 146.A N PHE 142.A O no hydrogen 2.767 N/A MET 147.A N THR 143.A O no hydrogen 2.676 N/A GLU 148.A N SER 144.A O no hydrogen 2.981 N/A ARG 149.A N LEU 145.A O no hydrogen 3.062 N/A ARG 149.A NH2 ASP 109.A OD1 no hydrogen 3.464 N/A LEU 150.A N LEU 146.A O no hydrogen 2.901 N/A SER 151.A N MET 147.A O no hydrogen 3.221 N/A SER 151.A OG MET 147.A O no hydrogen 3.084 N/A VAL 152.A N ARG 149.A O no hydrogen 3.200 N/A ASP 153.A N ARG 149.A O no hydrogen 2.862 N/A TYR 154.A N LEU 150.A O no hydrogen 2.968 N/A SER 158.A OG ASP 192.A OD2 no hydrogen 3.398 N/A LYS 159.A N ASP 192.A OD1 no hydrogen 2.783 N/A LYS 159.A NZ LYS 157.A O no hydrogen 3.107 N/A LEU 160.A N PHE 128.A O no hydrogen 2.836 N/A GLU 161.A N CYS 193.A O no hydrogen 2.925 N/A PHE 162.A N VAL 130.A O no hydrogen 2.736 N/A SER 163.A N PHE 195.A O no hydrogen 3.087 N/A SER 163.A OG HIS 132.A NE2 no hydrogen 3.028 N/A TYR 165.A N VAL 197.A O no hydrogen 2.808 N/A TYR 165.A OH ALA 380.A O no hydrogen 3.224 N/A GLN 169.A NE2 GLU 200.A OE2 no hydrogen 3.016 N/A SER 171.A OG TYR 217.A OH no hydrogen 2.695 N/A THR 172.A OG1 ALA 173.A O no hydrogen 3.051 N/A THR 172.A OG1 GLU 176.A OE1 no hydrogen 2.868 N/A GLU 176.A N ALA 173.A O no hydrogen 3.449 N/A TYR 178.A OH ALA 396.A O no hydrogen 2.824 N/A ASN 179.A N VAL 175.A O no hydrogen 3.202 N/A ASN 179.A ND2 ASN 94.A O no hydrogen 2.917 N/A ASN 179.A ND2 GLY 135.A O no hydrogen 3.184 N/A SER 180.A N GLU 176.A O no hydrogen 2.849 N/A SER 180.A OG PHE 134.A O no hydrogen 3.191 N/A SER 180.A OG GLU 176.A O no hydrogen 2.845 N/A ILE 181.A N PRO 177.A O no hydrogen 2.956 N/A LEU 182.A N TYR 178.A O no hydrogen 3.055 N/A THR 183.A N ASN 179.A O no hydrogen 3.239 N/A THR 184.A N SER 180.A O no hydrogen 3.296 N/A THR 184.A OG1 SER 180.A O no hydrogen 2.673 N/A HIS 185.A N ILE 181.A O no hydrogen 3.213 N/A THR 186.A OG1 TYR 96.A OH no hydrogen 2.986 N/A THR 186.A OG1 SER 144.A OG no hydrogen 2.698 N/A THR 186.A OG1 LEU 182.A O no hydrogen 2.839 N/A THR 186.A OG1 THR 183.A O no hydrogen 3.358 N/A THR 187.A N THR 183.A O no hydrogen 2.866 N/A THR 187.A N THR 184.A O no hydrogen 3.092 N/A LEU 188.A N THR 184.A O no hydrogen 2.788 N/A GLU 189.A N GLU 189.A OE2 no hydrogen 2.712 N/A HIS 190.A ND1 THR 186.A O no hydrogen 3.090 N/A ASP 192.A N LYS 159.A O no hydrogen 2.959 N/A ALA 194.A N HIS 259.A O no hydrogen 2.875 N/A PHE 195.A N GLU 161.A O no hydrogen 2.838 N/A VAL 197.A N SER 163.A O no hydrogen 2.905 N/A ASP 198.A N MET 295.A O no hydrogen 2.778 N/A ASN 199.A N TYR 165.A O no hydrogen 3.387 N/A GLU 200.A N ASP 198.A OD1 no hydrogen 3.059 N/A ILE 202.A N ASP 198.A O no hydrogen 3.163 N/A TYR 203.A N ASN 199.A O no hydrogen 2.883 N/A ASP 204.A N GLU 200.A O no hydrogen 2.771 N/A CYS 206.A SG TYR 203.A O no hydrogen 3.181 N/A CYS 206.A SG ILE 212.A O no hydrogen 3.517 N/A ASN 209.A ND2 ILE 205.A O no hydrogen 3.456 N/A ILE 212.A N CYS 206.A O no hydrogen 3.172 N/A ARG 214.A NH1 GLN 169.A O no hydrogen 3.187 N/A THR 216.A N ASN 219.A OD1 no hydrogen 3.301 N/A TYR 217.A OH SER 171.A OG no hydrogen 2.695 N/A LEU 220.A N THR 216.A O no hydrogen 2.959 N/A ASN 221.A N TYR 217.A O no hydrogen 2.659 N/A ARG 222.A N THR 218.A O no hydrogen 3.140 N/A ARG 222.A NE ASP 360.A OD2 no hydrogen 3.362 N/A LEU 223.A N LEU 220.A O no hydrogen 3.207 N/A ILE 224.A N LEU 220.A O no hydrogen 3.266 N/A SER 225.A N ASN 221.A O no hydrogen 2.833 N/A SER 225.A OG ASN 221.A O no hydrogen 3.277 N/A SER 225.A OG ARG 222.A O no hydrogen 2.720 N/A ILE 227.A N ILE 224.A O no hydrogen 3.031 N/A VAL 228.A N ILE 224.A O no hydrogen 2.993 N/A SER 229.A N SER 225.A O no hydrogen 2.739 N/A SER 229.A OG GLU 27.A OE2 no hydrogen 3.447 N/A SER 230.A OG GLN 226.A O no hydrogen 2.595 N/A ILE 231.A N ILE 227.A O no hydrogen 2.857 N/A THR 232.A N VAL 228.A O no hydrogen 2.991 N/A THR 232.A OG1 TYR 24.A OH no hydrogen 2.867 N/A THR 232.A OG1 VAL 228.A O no hydrogen 2.667 N/A SER 234.A OG LEU 241.A O no hydrogen 2.493 N/A ARG 236.A N THR 232.A O no hydrogen 2.819 N/A ARG 236.A NE THR 232.A OG1 no hydrogen 2.741 N/A ARG 236.A NH1 GLU 27.A OE2 no hydrogen 2.747 N/A PHE 237.A N ALA 233.A O no hydrogen 3.239 N/A ASP 238.A N SER 41.A OG no hydrogen 2.665 N/A ASN 242.A N GLU 247.A OE2 no hydrogen 2.749 N/A LEU 245.A N GLN 126.A OE1.A no hydrogen 2.816 N/A GLU 247.A N ASP 244.A O no hydrogen 3.150 N/A GLN 249.A N THR 246.A O no hydrogen 3.223 N/A GLN 249.A NE2 SER 158.A OG no hydrogen 2.750 N/A THR 250.A N THR 246.A O no hydrogen 3.461 N/A THR 250.A OG1 THR 246.A O no hydrogen 3.556 N/A ASN 251.A ND2 GLU 247.A O no hydrogen 2.810 N/A LEU 252.A N PHE 248.A O no hydrogen 3.156 N/A LEU 262.A N SER 372.A O no hydrogen 2.717 N/A TYR 265.A N ASN 293.A O no hydrogen 3.286 N/A ALA 266.A N VAL 368.A O no hydrogen 3.087 N/A SER 270.A OG ASN 209.A O no hydrogen 3.254 N/A ALA 274.A N GLU 272.A O no hydrogen 2.753 N/A ALA 282.A N THR 285.A OG1 no hydrogen 3.105 N/A CYS 288.A SG THR 285.A O no hydrogen 2.853 N/A PHE 289.A N ASN 286.A O no hydrogen 3.288 N/A GLU 290.A N ALA 287.A O no hydrogen 3.241 N/A ASN 293.A ND2 ALA 287.A O no hydrogen 3.610 N/A MET 295.A N ALA 263.A O no hydrogen 2.879 N/A LYS 297.A NZ GLU 200.A OE1 no hydrogen 2.898 N/A LYS 297.A NZ ASP 204.A OD1 no hydrogen 3.031 N/A CYS 298.A SG ALA 376.A O no hydrogen 3.240 N/A ASP 299.A N GLU 379.A OE1 no hydrogen 3.453 N/A TYR 305.A N GLN 335.A O no hydrogen 2.748 N/A CYS 308.A SG ALA 307.A O no hydrogen 3.763 N/A CYS 308.A SG LEU 371.A O no hydrogen 4.037 N/A CYS 309.A N LEU 371.A O no hydrogen 2.993 N/A LEU 311.A N CYS 369.A O no hydrogen 2.680 N/A TYR 312.A N GLY 347.A O no hydrogen 3.003 N/A ARG 313.A N ALA 367.A O no hydrogen 2.714 N/A ARG 313.A NH1 THR 354.A OG1 no hydrogen 3.088 N/A GLY 314.A N ASN 349.A O no hydrogen 2.976 N/A VAL 321.A N VAL 317.A O no hydrogen 3.367 N/A ASN 322.A N PRO 318.A O no hydrogen 2.873 N/A ALA 324.A N ASP 320.A O no hydrogen 3.006 N/A ILE 325.A N VAL 321.A O no hydrogen 3.048 N/A ALA 326.A N ASN 322.A O no hydrogen 3.318 N/A THR 327.A N ALA 323.A O no hydrogen 3.333 N/A THR 327.A OG1 ALA 323.A O no hydrogen 3.565 N/A THR 327.A OG1 ALA 324.A O no hydrogen 2.669 N/A LYS 329.A N ILE 325.A O no hydrogen 2.873 N/A THR 330.A OG1 ALA 326.A O no hydrogen 2.923 N/A THR 330.A OG1 THR 327.A O no hydrogen 3.077 N/A VAL 337.A N TYR 305.A O no hydrogen 2.792 N/A CYS 340.A SG MET 306.A O no hydrogen 3.383 N/A LYS 345.A N CYS 308.A O no hydrogen 2.981 N/A GLY 347.A N LEU 310.A O no hydrogen 3.007 N/A ASN 349.A N TYR 312.A O no hydrogen 3.017 N/A THR 354.A OG1 GLU 27.A OE1 no hydrogen 2.947 N/A GLY 359.A N VAL 356.A O no hydrogen 3.255 N/A ALA 362.A N ILE 269.A O no hydrogen 3.480 N/A LYS 363.A NZ PRO 353.A O no hydrogen 3.486 N/A ARG 366.A NE ASP 315.A O no hydrogen 2.780 N/A ALA 367.A N ARG 313.A O no hydrogen 2.702 N/A VAL 368.A N ALA 266.A O no hydrogen 2.722 N/A CYS 369.A N LEU 311.A O no hydrogen 2.626 N/A CYS 369.A SG THR 264.A O no hydrogen 3.610 N/A MET 370.A N THR 264.A O no hydrogen 3.041 N/A LEU 371.A N CYS 309.A O no hydrogen 3.105 N/A SER 372.A N LEU 262.A O no hydrogen 3.259 N/A SER 372.A OG LEU 262.A O no hydrogen 3.405 N/A SER 372.A OG TYR 305.A OH no hydrogen 3.257 N/A THR 375.A N LYS 304.A O no hydrogen 3.428 N/A THR 375.A OG1 LYS 304.A O no hydrogen 2.697 N/A ILE 377.A N THR 374.A O no hydrogen 3.179 N/A ALA 378.A N THR 375.A O no hydrogen 3.122 N/A GLU 379.A N ALA 376.A O no hydrogen 3.349 N/A TRP 381.A N ALA 378.A O no hydrogen 3.056 N/A ALA 382.A N ALA 378.A O no hydrogen 2.823 N/A ARG 383.A NH2 LYS 297.A O no hydrogen 3.423 N/A ASP 385.A N TRP 381.A O no hydrogen 2.885 N/A HIS 386.A N ALA 382.A O no hydrogen 3.268 N/A LYS 387.A N ARG 383.A O no hydrogen 3.464 N/A PHE 388.A N LEU 384.A O no hydrogen 3.032 N/A ASP 389.A N ASP 385.A O no hydrogen 2.946 N/A LEU 390.A N HIS 386.A O no hydrogen 2.925 N/A MET 391.A N LYS 387.A O no hydrogen 3.263 N/A TYR 392.A N PHE 388.A O no hydrogen 2.803 N/A TYR 392.A OH GLU 408.A O no hydrogen 3.004 N/A ALA 393.A N ASP 389.A O no hydrogen 3.172 N/A ARG 395.A N TYR 392.A O no hydrogen 3.183 N/A ARG 395.A NE TYR 392.A O no hydrogen 2.869 N/A ALA 396.A N MET 391.A O no hydrogen 2.996 N/A VAL 398.A N ARG 395.A O no hydrogen 3.356 N/A TRP 400.A N PHE 397.A O no hydrogen 3.219 N/A TYR 401.A N VAL 398.A O no hydrogen 2.955 N/A TYR 401.A OH ASN 179.A OD1 no hydrogen 2.650 N/A VAL 402.A N VAL 398.A O no hydrogen 3.032 N/A GLY 403.A N HIS 399.A O no hydrogen 3.027 N/A GLU 404.A N TYR 401.A O no hydrogen 2.970 N/A GLY 405.A N VAL 402.A O no hydrogen 2.966 N/A MET 406.A N TYR 401.A O no hydrogen 3.397 N/A GLU 410.A N GLU 407.A O no hydrogen 3.274 N/A PHE 411.A N GLU 408.A O no hydrogen 3.320 N/A SER 412.A OG GLY 409.A O no hydrogen 2.702 N/A GLU 413.A N GLY 409.A O no hydrogen 2.945 N/A ALA 414.A N GLU 410.A O no hydrogen 3.154 N/A ARG 415.A N PHE 411.A O no hydrogen 3.004 N/A GLU 416.A N SER 412.A O no hydrogen 3.024 N/A ASP 417.A N GLU 413.A O no hydrogen 3.189 N/A MET 418.A N ALA 414.A O no hydrogen 3.371 N/A ALA 419.A N ARG 415.A O no hydrogen 2.763 N/A ALA 420.A N GLU 416.A O no hydrogen 3.071 N/A LEU 421.A N ASP 417.A O no hydrogen 2.787 N/A GLU 422.A N MET 418.A O no hydrogen 2.864 N/A ASP 424.A N ALA 420.A O no hydrogen 2.797 N/A TYR 425.A N LEU 421.A O no hydrogen 3.002 N/A GLU 426.A N GLU 422.A O no hydrogen 2.966 N/A GLU 427.A N LYS 423.A O no hydrogen 2.694 N/A GLY 429.A N GLU 426.A O no hydrogen 3.157 N/A VAL 430.A N VAL 428.A O no hydrogen 2.995 N/A