Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4eek_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 5.A N ARG 163.A O no hydrogen 2.719 N/A VAL 7.A N PRO 104.A O no hydrogen 3.103 N/A LEU 8.A N VAL 165.A O no hydrogen 2.751 N/A PHE 9.A N ALA 106.A O no hydrogen 2.849 N/A ASP 10.A N ILE 167.A O no hydrogen 2.959 N/A GLY 13.A N VAL 16.A O no hydrogen 2.735 N/A VAL 14.A N LEU 11.A O no hydrogen 3.188 N/A LEU 15.A N LEU 11.A O no hydrogen 2.874 N/A VAL 16.A N LEU 11.A O no hydrogen 3.159 N/A GLU 17.A N THR 86.A O no hydrogen 2.717 N/A SER 18.A OG ASP 12.A OD2 no hydrogen 2.715 N/A ILE 21.A N GLU 17.A OE2 no hydrogen 3.120 N/A ILE 22.A N SER 18.A O no hydrogen 3.032 N/A ALA 23.A N GLU 19.A O no hydrogen 2.921 N/A GLN 24.A N GLY 20.A O no hydrogen 3.019 N/A GLN 24.A NE2.A GLN 24.A O no hydrogen 3.008 N/A GLN 24.A NE2.A GLN 27.A OE1 no hydrogen 2.993 N/A GLN 24.A NE2.A SER 28.A OG.C no hydrogen 3.008 N/A VAL 25.A N ILE 21.A O no hydrogen 3.219 N/A TRP 26.A N ILE 22.A O no hydrogen 3.158 N/A GLN 27.A N ALA 23.A O no hydrogen 2.931 N/A GLN 27.A NE2 LEU 37.A O no hydrogen 2.896 N/A SER 28.A N GLN 24.A O no hydrogen 2.972 N/A SER 28.A OG.A GLN 24.A O no hydrogen 3.159 N/A SER 28.A OG.A VAL 25.A O no hydrogen 3.088 N/A SER 28.A OG.B GLU 32.A OE2 no hydrogen 3.116 N/A SER 28.A OG.C GLN 24.A O no hydrogen 3.144 N/A VAL 29.A N VAL 25.A O no hydrogen 2.915 N/A LEU 30.A N TRP 26.A O no hydrogen 2.968 N/A ALA 31.A N GLN 27.A O no hydrogen 2.919 N/A GLU 32.A N SER 28.A O no hydrogen 3.004 N/A ARG 33.A N LEU 30.A O no hydrogen 2.846 N/A ARG 33.A NE ASP 69.A OD1 no hydrogen 3.022 N/A ARG 33.A NH1 VAL 29.A O no hydrogen 3.038 N/A ARG 33.A NH1 GLU 32.A OE1 no hydrogen 3.121 N/A ARG 33.A NH2 ASP 69.A OD2 no hydrogen 3.047 N/A GLY 34.A N ALA 31.A O no hydrogen 3.071 N/A LEU 35.A N LEU 30.A O no hydrogen 3.100 N/A THR 40.A OG1.A ASP 38.A OD1 no hydrogen 2.706 N/A GLU 41.A N ASP 38.A OD1 no hydrogen 2.732 N/A ILE 42.A N ASP 38.A O no hydrogen 3.154 N/A ALA 43.A N LEU 39.A O no hydrogen 2.851 N/A MET 44.A N THR 40.A O no hydrogen 2.914 N/A TYR 45.A N GLU 41.A O no hydrogen 2.985 N/A PHE 46.A N ILE 42.A O no hydrogen 2.834 N/A THR 47.A N ILE 42.A O no hydrogen 3.396 N/A THR 47.A OG1 GLU 19.A OE1 no hydrogen 3.081 N/A THR 47.A OG1 ALA 43.A O no hydrogen 2.477 N/A GLN 49.A N PHE 46.A O no hydrogen 3.215 N/A GLN 49.A NE2 TYR 45.A O no hydrogen 2.665 N/A VAL 54.A N ARG 50.A O no hydrogen 3.047 N/A LEU 55.A N PHE 51.A O no hydrogen 2.974 N/A ALA 56.A N ASP 52.A O no hydrogen 3.010 N/A TYR 57.A N GLY 53.A O no hydrogen 2.948 N/A TYR 57.A OH GLU 41.A OE2 no hydrogen 2.631 N/A LEU 58.A N VAL 54.A O no hydrogen 2.850 N/A ALA 59.A N LEU 55.A O no hydrogen 2.977 N/A GLN 60.A N ALA 56.A O no hydrogen 2.825 N/A GLN 61.A N TYR 57.A O no hydrogen 2.720 N/A GLN 61.A NE2 GLN 60.A OE1 no hydrogen 2.613 N/A HIS 62.A N LEU 58.A O no hydrogen 2.937 N/A HIS 62.A NE2 GLU 41.A OE2 no hydrogen 2.583 N/A ASP 63.A N ALA 59.A O no hydrogen 2.992 N/A PHE 64.A N LEU 58.A O no hydrogen 3.056 N/A PHE 70.A N PRO 67.A O no hydrogen 3.012 N/A VAL 73.A N ASP 69.A O no hydrogen 2.970 N/A LEU 74.A N PHE 70.A O no hydrogen 3.022 N/A GLU 75.A N LEU 71.A O no hydrogen 3.079 N/A THR 76.A N ASP 72.A O no hydrogen 2.909 N/A THR 76.A OG1 ASP 72.A O no hydrogen 3.173 N/A ARG 77.A N VAL 73.A O no hydrogen 2.959 N/A ARG 77.A N LEU 74.A O no hydrogen 2.987 N/A ARG 77.A NH1 GLU 32.A OE2 no hydrogen 2.672 N/A ARG 77.A NH2 GLU 32.A OE1 no hydrogen 2.842 N/A ARG 77.A NH2 GLU 32.A OE2 no hydrogen 3.038 N/A PHE 78.A N LEU 74.A O no hydrogen 2.739 N/A ASN 79.A N GLU 75.A O no hydrogen 3.158 N/A ALA 80.A N THR 76.A O no hydrogen 3.373 N/A ALA 81.A N ARG 77.A O no hydrogen 2.924 N/A MET 82.A N ASN 79.A O no hydrogen 3.295 N/A GLY 84.A N ALA 81.A O no hydrogen 2.793 N/A VAL 85.A N MET 82.A O no hydrogen 3.409 N/A ILE 88.A N LEU 15.A O no hydrogen 2.970 N/A GLU 89.A N GLU 89.A OE2.B no hydrogen 2.840 N/A ALA 91.A N ILE 88.A O no hydrogen 2.997 N/A THR 94.A N GLY 90.A O no hydrogen 2.997 N/A THR 94.A OG1 GLY 90.A O no hydrogen 3.319 N/A THR 94.A OG1 HIS 213.A ND1 no hydrogen 2.861 N/A LEU 95.A N ALA 91.A O no hydrogen 3.016 N/A ARG 96.A N ALA 92.A O no hydrogen 2.810 N/A ARG 96.A NE GLU 93.A OE1 no hydrogen 3.261 N/A ARG 96.A NH2 GLU 93.A OE1 no hydrogen 3.508 N/A ALA 97.A N GLU 93.A O no hydrogen 2.894 N/A LEU 98.A N THR 94.A O no hydrogen 3.039 N/A ARG 99.A N LEU 95.A O no hydrogen 2.974 N/A ARG 99.A NE LEU 128.A O no hydrogen 2.792 N/A ARG 99.A NH2 LEU 128.A O no hydrogen 3.479 N/A ALA 100.A N ARG 96.A O no hydrogen 2.900 N/A ALA 101.A N ALA 97.A O no hydrogen 3.027 N/A GLY 102.A N ARG 99.A O no hydrogen 3.126 N/A VAL 103.A N LEU 98.A O no hydrogen 2.981 N/A ALA 106.A N VAL 7.A O no hydrogen 3.185 N/A ILE 107.A N HIS 132.A O no hydrogen 2.907 N/A GLY 108.A N PHE 9.A O no hydrogen 2.864 N/A SER 109.A N TYR 134.A O no hydrogen 2.910 N/A SER 109.A OG SER 111.A OG no hydrogen 2.855 N/A ASN 110.A ND2 LYS 144.A O no hydrogen 2.947 N/A SER 111.A N SER 109.A OG no hydrogen 2.995 N/A SER 111.A OG SER 109.A OG no hydrogen 2.855 N/A ARG 113.A NH2.A SER 137.A OG no hydrogen 2.976 N/A GLY 114.A N GLU 112.A OE2 no hydrogen 2.840 N/A ARG 115.A N GLU 112.A OE1 no hydrogen 3.065 N/A LEU 116.A N GLU 112.A O no hydrogen 2.911 N/A HIS 117.A N ARG 113.A O no hydrogen 3.136 N/A LEU 118.A N GLY 114.A O no hydrogen 2.870 N/A LYS 119.A N ARG 115.A O no hydrogen 2.893 N/A LYS 119.A NZ ASP 12.A OD1 no hydrogen 3.011 N/A LYS 119.A NZ ASP 12.A OD2 no hydrogen 2.732 N/A LYS 119.A NZ SER 111.A OG no hydrogen 2.866 N/A LEU 120.A N LEU 116.A O no hydrogen 3.119 N/A ARG 121.A N HIS 117.A O no hydrogen 2.974 N/A VAL 122.A N LEU 118.A O no hydrogen 2.893 N/A ALA 123.A N LYS 119.A O no hydrogen 3.036 N/A GLY 124.A N ARG 121.A O no hydrogen 2.993 N/A LEU 125.A N LEU 120.A O no hydrogen 2.816 N/A GLU 127.A N GLU 127.A OE1 no hydrogen 2.684 N/A ALA 129.A N LEU 125.A O no hydrogen 2.808 N/A HIS 132.A ND1 TYR 134.A OH no hydrogen 3.042 N/A TYR 134.A N ILE 107.A O no hydrogen 2.830 N/A TYR 134.A OH HIS 132.A ND1 no hydrogen 3.042 N/A SER 137.A N ASP 135.A OD2 no hydrogen 2.939 N/A SER 137.A OG ASP 135.A OD1 no hydrogen 3.512 N/A SER 137.A OG ASP 135.A OD2 no hydrogen 2.561 N/A TRP 138.A N ASP 135.A O no hydrogen 3.078 N/A VAL 139.A N PRO 136.A O no hydrogen 2.899 N/A GLY 141.A N PRO 136.A O no hydrogen 2.878 N/A ARG 142.A N VAL 139.A O no hydrogen 3.135 N/A ARG 142.A NE ASP 148.A OD1 no hydrogen 3.515 N/A ARG 142.A NE ASP 148.A OD2 no hydrogen 2.891 N/A GLY 143.A N GLY 141.A O no hydrogen 2.909 N/A LYS 144.A N ASN 110.A OD1 no hydrogen 2.774 N/A LYS 144.A NZ GLY 108.A O no hydrogen 2.826 N/A LYS 144.A NZ GLU 168.A OE2 no hydrogen 2.802 N/A HIS 146.A N GLY 143.A O no hydrogen 2.979 N/A TYR 150.A N PRO 147.A O no hydrogen 2.933 N/A TYR 150.A OH GLU 168.A OE2 no hydrogen 2.583 N/A THR 151.A N PRO 147.A O no hydrogen 2.949 N/A THR 151.A OG1 PRO 147.A O no hydrogen 3.278 N/A PHE 152.A N ASP 148.A O no hydrogen 2.775 N/A ALA 153.A N LEU 149.A O no hydrogen 2.909 N/A ALA 154.A N TYR 150.A O no hydrogen 3.007 N/A GLN 155.A N THR 151.A O no hydrogen 3.000 N/A GLN 155.A NE2 GLN 156.A OE1 no hydrogen 3.257 N/A GLN 156.A N PHE 152.A O no hydrogen 2.889 N/A LEU 157.A N ALA 153.A O no hydrogen 3.237 N/A LEU 157.A N ALA 154.A O no hydrogen 3.081 N/A GLY 158.A N GLN 155.A O no hydrogen 2.929 N/A ILE 159.A N ALA 154.A O no hydrogen 3.037 N/A ARG 163.A N LEU 160.A O no hydrogen 2.906 N/A ARG 163.A NE ASP 5.A OD2 no hydrogen 3.039 N/A ARG 163.A NH1 ALA 2.A O no hydrogen 3.012 N/A ARG 163.A NH2 ALA 2.A O no hydrogen 2.889 N/A ARG 163.A NH2 ASP 5.A OD1 no hydrogen 2.895 N/A CYS 164.A N PRO 161.A O no hydrogen 2.931 N/A CYS 164.A SG LEU 160.A O no hydrogen 3.607 N/A VAL 165.A N ALA 6.A O no hydrogen 3.064 N/A VAL 166.A N THR 183.A O no hydrogen 2.806 N/A ILE 167.A N LEU 8.A O no hydrogen 2.852 N/A GLU 168.A N TRP 185.A O no hydrogen 3.218 N/A ASP 169.A N GLU 168.A OE1 no hydrogen 3.321 N/A VAL 171.A N ASP 196.A OD2 no hydrogen 2.804 N/A GLY 173.A N SER 170.A OG no hydrogen 2.920 N/A GLY 174.A N SER 170.A O no hydrogen 2.811 N/A ALA 175.A N VAL 171.A O no hydrogen 2.819 N/A ALA 176.A N THR 172.A O no hydrogen 3.363 N/A GLY 177.A N GLY 173.A O no hydrogen 3.140 N/A LEU 178.A N GLY 174.A O no hydrogen 2.948 N/A ALA 179.A N ALA 175.A O no hydrogen 2.768 N/A ALA 180.A N ALA 176.A O no hydrogen 3.041 N/A ALA 180.A N GLY 177.A O no hydrogen 3.149 N/A GLY 181.A N LEU 178.A O no hydrogen 2.913 N/A ALA 182.A N GLY 177.A O no hydrogen 3.065 N/A THR 183.A N CYS 164.A O no hydrogen 3.059 N/A TRP 185.A N VAL 166.A O no hydrogen 2.894 N/A GLY 186.A N ARG 208.A O no hydrogen 2.846 N/A LEU 187.A N GLU 168.A O no hydrogen 2.904 N/A LEU 188.A N LEU 210.A O no hydrogen 2.855 N/A HIS 192.A ND1 GLU 17.A OE1 no hydrogen 2.800 N/A HIS 192.A NE2 GLU 89.A OE2.B no hydrogen 2.664 N/A HIS 194.A ND1 ASP 169.A OD2 no hydrogen 2.614 N/A HIS 194.A NE2 VAL 189.A O no hydrogen 2.687 N/A LEU 201.A N GLY 197.A O no hydrogen 3.057 N/A SER 202.A N ALA 198.A O no hydrogen 2.913 N/A SER 202.A OG.A ALA 198.A O no hydrogen 3.224 N/A ARG 203.A N ALA 199.A O no hydrogen 2.858 N/A LEU 204.A N ALA 200.A O no hydrogen 2.825 N/A GLY 205.A N LEU 201.A O no hydrogen 3.187 N/A GLY 205.A N SER 202.A O no hydrogen 3.068 N/A ALA 206.A N LEU 201.A O no hydrogen 2.920 N/A ALA 207.A N LEU 184.A O no hydrogen 2.803 N/A LEU 210.A N GLY 186.A O no hydrogen 2.810 N/A THR 211.A N GLU 215.A OE1.A no hydrogen 2.937 N/A THR 211.A N GLU 215.A OE1.B no hydrogen 2.651 N/A THR 211.A OG1 GLU 215.A OE1.A no hydrogen 3.519 N/A THR 211.A OG1 GLU 215.A OE1.B no hydrogen 2.907 N/A THR 211.A OG1 GLU 215.A OE2.B no hydrogen 3.357 N/A HIS 213.A ND1 THR 94.A OG1 no hydrogen 2.861 N/A HIS 213.A NE2 VAL 14.A O no hydrogen 2.800 N/A GLU 215.A N SER 212.A OG no hydrogen 2.896 N/A LEU 216.A N SER 212.A O no hydrogen 2.995 N/A ARG 217.A N HIS 213.A O no hydrogen 2.940 N/A ARG 217.A NH2 GLY 90.A O no hydrogen 3.140 N/A ARG 217.A NH2 THR 94.A OG1 no hydrogen 2.920 N/A ALA 218.A N ALA 214.A O no hydrogen 3.004 N/A ALA 219.A N GLU 215.A O no hydrogen 2.899 N/A LEU 220.A N LEU 216.A O no hydrogen 2.832 N/A ALA 221.A N ARG 217.A O no hydrogen 2.928 N/A GLU 222.A N ALA 218.A O no hydrogen 3.016 N/A ALA 223.A N ALA 219.A O no hydrogen 2.976 N/A GLY 224.A N ALA 221.A O no hydrogen 2.899 N/A LEU 225.A N LEU 220.A O no hydrogen 2.978 N/A