Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4ef2_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 4.A N ASP 1.A O no hydrogen 3.148 N/A LEU 5.A N LYS 31.A O no hydrogen 2.760 N/A LYS 6.A N ASP 53.A OD2 no hydrogen 2.830 N/A VAL 7.A N GLU 33.A O no hydrogen 2.877 N/A GLY 8.A N ALA 54.A O no hydrogen 2.912 N/A ALA 9.A N THR 35.A O no hydrogen 3.025 N/A HIS 14.A NE2 ASN 201.A OD1 no hydrogen 2.864 N/A ALA 15.A N SER 10.A O no hydrogen 2.896 N/A ILE 17.A N PRO 13.A O no hydrogen 2.806 N/A LEU 18.A N HIS 14.A O no hydrogen 2.991 N/A GLU 19.A N ALA 15.A O no hydrogen 2.944 N/A HIS 20.A N GLU 16.A O no hydrogen 3.002 N/A VAL 21.A N ILE 17.A O no hydrogen 3.000 N/A LYS 22.A N GLU 19.A O no hydrogen 3.341 N/A LYS 22.A NZ GLU 19.A OE1 no hydrogen 2.920 N/A LYS 22.A NZ GLU 19.A OE2 no hydrogen 3.399 N/A LEU 25.A N VAL 21.A O no hydrogen 3.016 N/A GLU 26.A N LYS 22.A O no hydrogen 2.890 N/A LYS 27.A N PRO 23.A O no hydrogen 3.083 N/A GLU 28.A N LEU 24.A O no hydrogen 3.353 N/A GLY 29.A N GLU 26.A O no hydrogen 2.771 N/A VAL 30.A N LEU 25.A O no hydrogen 2.884 N/A LYS 31.A N SER 3.A O no hydrogen 2.762 N/A GLU 33.A N LEU 5.A O no hydrogen 2.916 N/A THR 35.A N VAL 7.A O no hydrogen 2.843 N/A TYR 37.A N ALA 9.A O no hydrogen 2.976 N/A TYR 40.A OH ASN 176.A OD1 no hydrogen 2.481 N/A VAL 41.A N ASP 39.A OD2 no hydrogen 2.909 N/A LEU 42.A N ASP 39.A OD2 no hydrogen 2.849 N/A ASN 44.A ND2 GLN 58.A OE1 no hydrogen 3.053 N/A LYS 45.A N VAL 41.A O no hydrogen 3.218 N/A ALA 46.A N LEU 42.A O no hydrogen 2.704 N/A LEU 47.A N PRO 43.A O no hydrogen 3.013 N/A GLU 48.A N ASN 44.A O no hydrogen 2.884 N/A SER 49.A N LYS 45.A O no hydrogen 2.981 N/A SER 49.A OG LYS 45.A O no hydrogen 3.484 N/A SER 49.A OG ALA 46.A O no hydrogen 3.253 N/A GLY 50.A N LEU 47.A O no hydrogen 3.276 N/A ILE 52.A N ALA 46.A O no hydrogen 3.463 N/A ASP 53.A N LYS 6.A O no hydrogen 2.801 N/A ALA 54.A N LYS 6.A O no hydrogen 3.039 N/A ASN 55.A N ALA 204.A O no hydrogen 2.947 N/A ASN 55.A ND2 PRO 43.A O no hydrogen 3.174 N/A ASN 55.A ND2 ASN 44.A OD1 no hydrogen 2.968 N/A TYR 56.A N GLY 8.A O no hydrogen 2.794 N/A TYR 56.A OH HIS 81.A ND1 no hydrogen 2.686 N/A GLN 58.A NE2 ASN 44.A OD1 no hydrogen 2.990 N/A GLN 58.A NE2 ASN 55.A OD1 no hydrogen 3.213 N/A HIS 59.A NE2 ASP 112.A OD1 no hydrogen 2.915 N/A PHE 62.A N HIS 59.A ND1 no hydrogen 3.135 N/A PHE 63.A N HIS 59.A O no hydrogen 2.845 N/A ASN 64.A N VAL 60.A O no hydrogen 2.812 N/A GLU 65.A N PRO 61.A O no hydrogen 3.248 N/A ALA 66.A N PHE 62.A O no hydrogen 2.931 N/A VAL 67.A N PHE 63.A O no hydrogen 2.809 N/A LYS 68.A N ASN 64.A O no hydrogen 3.095 N/A GLU 69.A N GLU 65.A O no hydrogen 2.813 N/A ASN 70.A N ALA 66.A O no hydrogen 3.024 N/A ASN 70.A ND2 ALA 66.A O no hydrogen 2.994 N/A TYR 72.A N VAL 67.A O no hydrogen 3.272 N/A VAL 75.A N VAL 205.A O no hydrogen 2.754 N/A ALA 77.A N ILE 203.A O no hydrogen 2.831 N/A GLY 78.A N ASN 76.A OD1 no hydrogen 2.711 N/A ILE 80.A N ASN 201.A O no hydrogen 2.837 N/A HIS 81.A ND1 TYR 56.A OH no hydrogen 2.686 N/A HIS 81.A NE2 GLU 83.A OE2 no hydrogen 2.935 N/A LEU 82.A N VAL 240.A O no hydrogen 2.647 N/A VAL 85.A N GLU 193.A OE1 no hydrogen 3.188 N/A LEU 87.A N ALA 191.A O no hydrogen 2.995 N/A TYR 88.A N VAL 171.A O no hydrogen 2.856 N/A SER 89.A OG ALA 169.A O no hydrogen 2.706 N/A LYS 90.A NZ ASP 164.A O no hydrogen 3.167 N/A LYS 90.A NZ ASP 164.A OD1 no hydrogen 2.983 N/A LYS 91.A N SER 89.A OG no hydrogen 2.998 N/A LYS 91.A NZ GLU 166.A O no hydrogen 2.903 N/A LYS 91.A NZ GLY 168.A O no hydrogen 2.782 N/A TYR 92.A N SER 89.A OG no hydrogen 3.051 N/A LYS 93.A N GLU 97.A OE1 no hydrogen 2.888 N/A SER 94.A N GLU 97.A OE1 no hydrogen 3.329 N/A GLN 96.A N SER 94.A OG no hydrogen 3.008 N/A GLN 96.A NE2 ALA 123.A O no hydrogen 2.893 N/A GLU 97.A N SER 94.A O no hydrogen 3.188 N/A ILE 98.A N LEU 95.A O no hydrogen 3.115 N/A GLY 101.A N LYS 147.A O no hydrogen 2.883 N/A SER 102.A N PRO 99.A O no hydrogen 3.244 N/A SER 102.A OG PRO 99.A O no hydrogen 2.545 N/A ILE 104.A N LYS 150.A O no hydrogen 2.855 N/A TYR 105.A N ALA 170.A O no hydrogen 2.970 N/A VAL 106.A N ASN 152.A O no hydrogen 2.839 N/A SER 108.A N SER 155.A O no hydrogen 2.758 N/A SER 108.A OG SER 155.A O no hydrogen 3.200 N/A SER 109.A N SER 107.A OG no hydrogen 2.940 N/A ASP 112.A N SER 109.A O no hydrogen 3.041 N/A TRP 113.A N VAL 110.A O no hydrogen 3.030 N/A TRP 113.A NE1 SER 107.A O no hydrogen 3.060 N/A ARG 115.A N ASP 112.A O no hydrogen 2.986 N/A ARG 115.A NE GLU 193.A OE1 no hydrogen 3.456 N/A ARG 115.A NE GLU 193.A OE2 no hydrogen 2.784 N/A ARG 115.A NH1 ASP 112.A OD1 no hydrogen 3.059 N/A ARG 115.A NH2 GLU 83.A O no hydrogen 2.952 N/A ARG 115.A NH2 GLU 193.A OE1 no hydrogen 2.888 N/A LEU 117.A N TRP 113.A O no hydrogen 3.230 N/A THR 118.A N PRO 114.A O no hydrogen 2.915 N/A THR 118.A OG1 ARG 115.A O no hydrogen 2.884 N/A ILE 119.A N ARG 115.A O no hydrogen 3.119 N/A LEU 120.A N VAL 116.A O no hydrogen 3.077 N/A GLU 121.A N LEU 117.A O no hydrogen 2.992 N/A ASP 122.A N THR 118.A O no hydrogen 2.910 N/A ALA 123.A N ILE 119.A O no hydrogen 2.817 N/A GLY 124.A N GLU 121.A O no hydrogen 2.963 N/A LEU 125.A N LEU 120.A O no hydrogen 2.858 N/A ILE 126.A N LEU 120.A O no hydrogen 3.412 N/A THR 127.A N LYS 144.A O no hydrogen 3.089 N/A LYS 129.A N ASP 141.A O no hydrogen 2.899 N/A VAL 132.A N LYS 129.A O no hydrogen 2.973 N/A ARG 134.A NH1 GLU 121.A OE1 no hydrogen 2.798 N/A ARG 134.A NH2 GLU 121.A OE2 no hydrogen 2.990 N/A THR 135.A N ASP 133.A OD1 no hydrogen 2.729 N/A THR 135.A OG1 ASP 133.A OD1 no hydrogen 2.485 N/A THR 135.A OG1 ASP 133.A OD2 no hydrogen 3.351 N/A THR 136.A N ASP 133.A O no hydrogen 2.987 N/A THR 136.A OG1 ASP 133.A O no hydrogen 3.445 N/A THR 138.A N ASP 141.A OD2 no hydrogen 2.796 N/A ASP 140.A N THR 138.A OG1 no hydrogen 3.338 N/A ASP 141.A N THR 138.A O no hydrogen 2.866 N/A ILE 142.A N PHE 139.A O no hydrogen 3.295 N/A ASP 143.A N THR 127.A O no hydrogen 2.694 N/A LYS 144.A N THR 127.A OG1 no hydrogen 2.952 N/A ASN 145.A ND2 LEU 149.A O no hydrogen 2.837 N/A THR 146.A N LEU 125.A O no hydrogen 2.944 N/A LYS 147.A NZ GLN 96.A O no hydrogen 2.904 N/A LYS 147.A NZ ILE 98.A O no hydrogen 2.723 N/A LYS 148.A N ASN 145.A O no hydrogen 2.972 N/A LYS 148.A NZ THR 146.A O no hydrogen 2.828 N/A LEU 149.A N ASN 145.A OD1 no hydrogen 2.939 N/A LYS 150.A N SER 102.A O no hydrogen 2.965 N/A LYS 150.A NZ GLY 101.A O no hydrogen 3.264 N/A ASN 152.A N ILE 104.A O no hydrogen 2.969 N/A GLU 154.A N ASN 152.A OD1 no hydrogen 3.126 N/A ALA 158.A N ASP 156.A OD1 no hydrogen 2.812 N/A ILE 159.A N ASP 156.A O no hydrogen 2.999 N/A THR 161.A N ILE 159.A O no hydrogen 2.798 N/A LEU 162.A N ILE 159.A O no hydrogen 3.258 N/A ASP 164.A N THR 160.A O no hydrogen 2.920 N/A ASN 165.A N THR 161.A O no hydrogen 2.732 N/A GLU 166.A N TYR 163.A O no hydrogen 3.112 N/A GLU 167.A N LEU 162.A O no hydrogen 3.032 N/A ALA 169.A N THR 103.A O no hydrogen 2.912 N/A VAL 171.A N TYR 88.A O no hydrogen 2.837 N/A LEU 172.A N TYR 105.A O no hydrogen 2.941 N/A ILE 173.A N GLY 86.A O no hydrogen 3.371 N/A ASN 174.A ND2 ASP 112.A OD2 no hydrogen 3.061 N/A SER 175.A OG PRO 84.A O no hydrogen 3.222 N/A ASN 176.A N GLU 83.A OE1 no hydrogen 3.004 N/A ALA 178.A N ASN 174.A O no hydrogen 3.001 N/A VAL 179.A N SER 175.A O no hydrogen 2.670 N/A ASP 180.A N ASN 176.A O no hydrogen 3.248 N/A GLN 181.A N PHE 177.A O no hydrogen 3.084 N/A GLN 181.A N ALA 178.A O no hydrogen 3.239 N/A GLY 182.A N VAL 179.A O no hydrogen 3.015 N/A LEU 183.A N ALA 178.A O no hydrogen 2.797 N/A ASN 184.A N ASP 188.A OD2 no hydrogen 2.726 N/A LYS 186.A N ASN 184.A OD1 no hydrogen 3.064 N/A LYS 187.A N ASN 184.A O no hydrogen 2.966 N/A ASP 188.A N ASN 184.A O no hydrogen 2.645 N/A ILE 190.A N LEU 87.A O no hydrogen 2.806 N/A GLU 193.A N VAL 85.A O no hydrogen 2.811 N/A LYS 194.A NZ ASP 122.A OD1 no hydrogen 3.125 N/A SER 197.A N GLU 195.A OE2 no hydrogen 3.242 N/A SER 197.A OG GLU 195.A OE2 no hydrogen 3.121 N/A TYR 199.A N SER 196.A O no hydrogen 2.833 N/A ASN 201.A N HIS 81.A O no hydrogen 2.676 N/A ASN 201.A ND2 TYR 199.A O no hydrogen 3.144 N/A ILE 202.A N GLN 58.A O no hydrogen 2.959 N/A ILE 203.A N GLY 78.A O no hydrogen 3.060 N/A ALA 204.A N ASN 55.A O no hydrogen 3.081 N/A VAL 205.A N VAL 75.A O no hydrogen 3.121 N/A ARG 206.A NE GLU 208.A OE2 no hydrogen 3.207 N/A ARG 206.A NH1 LEU 47.A O no hydrogen 2.790 N/A ARG 206.A NH1 ILE 52.A O no hydrogen 2.711 N/A LYS 207.A N ASP 73.A O no hydrogen 3.040 N/A LYS 207.A NZ GLU 210.A OE1 no hydrogen 3.098 N/A LYS 207.A NZ GLU 210.A OE2 no hydrogen 3.042 N/A GLU 208.A N GLU 208.A OE1 no hydrogen 2.998 N/A ASP 209.A N ARG 206.A O no hydrogen 2.912 N/A GLU 210.A N LYS 207.A O no hydrogen 3.081 N/A ASN 212.A N ASP 209.A O no hydrogen 2.910 N/A ASN 214.A ND2 ASP 2.A O no hydrogen 3.087 N/A VAL 215.A N ASN 212.A OD1 no hydrogen 2.964 N/A LYS 216.A N ASN 212.A O no hydrogen 3.031 N/A LYS 217.A N GLU 213.A O no hydrogen 3.014 N/A LYS 217.A NZ GLU 28.A O no hydrogen 3.049 N/A LYS 217.A NZ GLU 213.A OE1 no hydrogen 3.370 N/A LEU 218.A N ASN 214.A O no hydrogen 3.092 N/A VAL 219.A N VAL 215.A O no hydrogen 3.034 N/A LYS 220.A N LYS 216.A O no hydrogen 2.946 N/A VAL 221.A N LYS 217.A O no hydrogen 3.019 N/A LEU 222.A N LEU 218.A O no hydrogen 2.969 N/A ARG 223.A N VAL 219.A O no hydrogen 3.072 N/A SER 224.A N VAL 221.A O no hydrogen 3.184 N/A SER 224.A OG VAL 221.A O no hydrogen 2.713 N/A GLN 228.A N SER 224.A O no hydrogen 2.858 N/A GLN 228.A NE2.A ILE 80.A O no hydrogen 3.066 N/A GLN 228.A NE2.A LEU 222.A O no hydrogen 2.690 N/A ASP 229.A N LYS 225.A O no hydrogen 2.901 N/A TRP 230.A N GLU 226.A O no hydrogen 3.050 N/A ILE 231.A N VAL 227.A O no hydrogen 2.891 N/A THR 232.A N GLN 228.A O no hydrogen 3.056 N/A THR 232.A OG1 GLN 228.A O no hydrogen 3.098 N/A LYS 233.A N ASP 229.A O no hydrogen 3.063 N/A LYS 234.A N TRP 230.A O no hydrogen 2.930 N/A TRP 235.A N ILE 231.A O no hydrogen 3.406 N/A ASN 236.A N LYS 233.A O no hydrogen 3.426 N/A GLY 237.A N THR 232.A O no hydrogen 3.117 N/A ALA 238.A N TRP 235.A O no hydrogen 2.891 N/A VAL 240.A N LEU 82.A O no hydrogen 2.917 N/A VAL 242.A N ILE 80.A O no hydrogen 3.235 N/A