Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4efr_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 5.A N PRO 2.A O no hydrogen 3.001 N/A LEU 6.A N PRO 2.A O no hydrogen 3.241 N/A GLU 7.A N ASN 3.A O no hydrogen 3.016 N/A GLU 8.A N ASP 4.A O no hydrogen 3.298 N/A GLN 9.A N ILE 5.A O no hydrogen 2.810 N/A LEU 10.A N LEU 6.A O no hydrogen 2.762 N/A TYR 11.A N GLU 7.A O no hydrogen 2.691 N/A ASN 12.A N GLU 8.A O no hydrogen 2.802 N/A SER 13.A OG GLN 9.A O no hydrogen 3.498 N/A SER 13.A OG LEU 10.A O no hydrogen 2.744 N/A ILE 14.A N TYR 11.A O no hydrogen 3.238 N/A VAL 15.A N TYR 11.A O no hydrogen 3.147 N/A VAL 16.A N ASN 12.A O no hydrogen 3.198 N/A ALA 17.A N ILE 14.A O no hydrogen 3.102 N/A ASP 18.A N SER 13.A O no hydrogen 2.506 N/A TYR 19.A OH ASN 52.A OD1 no hydrogen 3.058 N/A SER 21.A N ASP 18.A OD1 no hydrogen 3.131 N/A ALA 22.A N ASP 18.A O no hydrogen 3.009 N/A VAL 23.A N TYR 19.A O no hydrogen 2.871 N/A GLU 24.A N ASP 20.A O no hydrogen 3.291 N/A LYS 25.A N SER 21.A O no hydrogen 3.041 N/A SER 26.A N ALA 22.A O no hydrogen 3.011 N/A SER 26.A N VAL 23.A O no hydrogen 2.876 N/A SER 26.A OG ALA 22.A O no hydrogen 2.823 N/A SER 26.A OG TYR 56.A OH no hydrogen 2.799 N/A LYS 27.A N VAL 23.A O no hydrogen 2.977 N/A LYS 27.A N GLU 24.A O no hydrogen 2.886 N/A LYS 27.A NZ GLN 63.A O no hydrogen 2.936 N/A LYS 27.A NZ SER 65.A OG no hydrogen 2.384 N/A HIS 28.A N GLU 24.A O no hydrogen 2.978 N/A LEU 29.A N LYS 25.A O no hydrogen 3.073 N/A TYR 30.A N SER 26.A O no hydrogen 3.247 N/A GLU 31.A N LYS 27.A O no hydrogen 2.780 N/A GLU 32.A N HIS 28.A O no hydrogen 2.664 N/A LYS 33.A N TYR 30.A O no hydrogen 3.144 N/A LYS 34.A N LEU 29.A O no hydrogen 2.588 N/A GLU 36.A N GLU 36.A OE2 no hydrogen 2.387 N/A VAL 37.A N LYS 34.A O no hydrogen 3.063 N/A THR 39.A N SER 35.A O no hydrogen 3.068 N/A THR 39.A OG1 CYS 72.A O no hydrogen 3.203 N/A ASN 40.A N GLU 36.A O no hydrogen 3.003 N/A VAL 41.A N VAL 37.A O no hydrogen 2.976 N/A VAL 42.A N ILE 38.A O no hydrogen 2.802 N/A ASN 43.A N THR 39.A O no hydrogen 2.878 N/A LYS 44.A N ASN 40.A O no hydrogen 3.141 N/A LEU 45.A N VAL 41.A O no hydrogen 3.053 N/A LEU 45.A N VAL 42.A O no hydrogen 2.899 N/A ILE 46.A N VAL 42.A O no hydrogen 3.018 N/A ARG 47.A N ASN 43.A O no hydrogen 3.073 N/A ASN 48.A N LYS 44.A O no hydrogen 3.318 N/A ASN 48.A N LEU 45.A O no hydrogen 2.887 N/A LYS 50.A N LEU 45.A O no hydrogen 3.195 N/A ASN 52.A ND2 ILE 14.A O no hydrogen 3.062 N/A CYS 53.A N LYS 50.A O no hydrogen 2.973 N/A MET 54.A N MET 51.A O no hydrogen 2.889 N/A GLU 55.A N ASN 52.A O no hydrogen 3.126 N/A TYR 56.A N ASN 52.A O no hydrogen 3.207 N/A TYR 56.A OH SER 26.A OG no hydrogen 2.799 N/A ALA 57.A N CYS 53.A O no hydrogen 3.169 N/A TYR 58.A N MET 54.A O no hydrogen 2.951 N/A GLN 59.A N GLU 55.A O no hydrogen 3.019 N/A LEU 60.A N TYR 56.A O no hydrogen 3.360 N/A TRP 61.A N ALA 57.A O no hydrogen 3.000 N/A LEU 62.A N TYR 58.A O no hydrogen 2.973 N/A LEU 62.A N GLN 59.A O no hydrogen 3.217 N/A GLN 63.A N LEU 60.A O no hydrogen 3.206 N/A GLN 63.A NE2 ASP 20.A OD1 no hydrogen 2.736 N/A GLN 63.A NE2 GLN 59.A OE1 no hydrogen 2.691 N/A SER 65.A N LEU 60.A O no hydrogen 2.790 N/A LYS 66.A NZ TRP 61.A O no hydrogen 3.239 N/A ILE 68.A N SER 65.A O no hydrogen 2.810 N/A VAL 69.A N LYS 66.A O no hydrogen 2.920 N/A ARG 70.A N LYS 66.A O no hydrogen 3.088 N/A ASP 71.A N ASP 67.A O no hydrogen 2.936 N/A CYS 72.A N ILE 68.A O no hydrogen 2.852 N/A CYS 72.A SG SER 35.A OG no hydrogen 3.269 N/A GLU 76.A N GLU 76.A OE1 no hydrogen 2.929 N/A PHE 77.A N PRO 74.A O no hydrogen 3.205 N/A ARG 78.A N VAL 75.A O no hydrogen 3.087 N/A LEU 79.A N VAL 75.A O no hydrogen 3.151 N/A ILE 80.A N GLU 76.A O no hydrogen 2.736 N/A PHE 81.A N PHE 77.A O no hydrogen 3.068 N/A ALA 82.A N ARG 78.A O no hydrogen 2.810 N/A GLU 83.A N ILE 80.A O no hydrogen 3.196 N/A ASN 84.A N LEU 79.A O no hydrogen 3.191 N/A ILE 86.A N TRP 125.A O no hydrogen 2.685 N/A LYS 87.A N LYS 232.A O no hydrogen 2.612 N/A LYS 87.A NZ LYS 118.A O no hydrogen 3.335 N/A MET 89.A N GLY 230.A O no hydrogen 2.649 N/A TYR 90.A N LEU 95.A O no hydrogen 3.008 N/A LYS 91.A N ALA 228.A O no hydrogen 3.331 N/A LYS 91.A NZ ASP 185.A OD2 no hydrogen 2.524 N/A GLY 94.A N TYR 90.A O no hydrogen 2.691 N/A LEU 97.A N LEU 88.A O no hydrogen 2.973 N/A THR 98.A N PHE 112.A O no hydrogen 2.840 N/A THR 98.A OG1 LEU 99.A O no hydrogen 3.503 N/A THR 98.A OG1 LYS 122.A O no hydrogen 3.183 N/A LEU 99.A N THR 98.A OG1 no hydrogen 2.493 N/A SER 100.A N LEU 110.A O no hydrogen 2.879 N/A SER 100.A OG ASP 102.A O no hydrogen 3.135 N/A SER 100.A OG LEU 110.A O no hydrogen 3.445 N/A VAL 103.A N ASP 102.A OD1 no hydrogen 2.646 N/A HIS 104.A N GLY 108.A O no hydrogen 2.605 N/A GLY 105.A N VAL 103.A O no hydrogen 3.081 N/A ASP 107.A N HIS 104.A O no hydrogen 3.292 N/A ARG 109.A N GLY 165.A O no hydrogen 2.767 N/A ARG 109.A NE ASN 101.A O no hydrogen 2.955 N/A ARG 109.A NH1 GLN 147.A OE1 no hydrogen 3.326 N/A ARG 109.A NH2 ASN 101.A O no hydrogen 3.236 N/A LEU 110.A N SER 100.A OG no hydrogen 2.905 N/A ALA 111.A N ALA 163.A O no hydrogen 2.811 N/A PHE 112.A N THR 98.A O no hydrogen 3.068 N/A GLY 113.A N ARG 211.A O no hydrogen 2.843 N/A ASP 114.A N ALA 96.A O no hydrogen 3.134 N/A GLY 115.A N ASN 210.A OD1 no hydrogen 3.021 N/A LYS 116.A N ASP 114.A OD2 no hydrogen 3.233 N/A ASP 117.A N ASP 114.A OD2 no hydrogen 2.977 N/A THR 119.A N ASP 117.A OD1 no hydrogen 3.319 N/A SER 120.A N ASP 117.A OD1 no hydrogen 2.914 N/A LYS 122.A N SER 120.A OG no hydrogen 3.263 N/A LYS 122.A NZ ASN 101.A OD1 no hydrogen 2.687 N/A LYS 122.A NZ GLU 144.A OE2 no hydrogen 3.135 N/A VAL 123.A N SER 120.A O no hydrogen 3.120 N/A SER 124.A N PRO 121.A O no hydrogen 3.271 N/A SER 124.A OG THR 143.A OG1 no hydrogen 3.065 N/A TRP 125.A N ILE 86.A O no hydrogen 2.660 N/A TRP 125.A NE1 LEU 97.A O no hydrogen 2.758 N/A LYS 126.A N LEU 141.A O no hydrogen 3.156 N/A ILE 128.A N LYS 139.A O no hydrogen 2.743 N/A LEU 130.A N TYR 137.A O no hydrogen 2.792 N/A GLU 132.A N LYS 135.A O no hydrogen 3.036 N/A ASN 134.A ND2 ALA 17.A O no hydrogen 3.302 N/A LYS 135.A N GLU 132.A O no hydrogen 2.877 N/A VAL 136.A N GLU 55.A OE2 no hydrogen 3.159 N/A TYR 137.A N LEU 130.A O no hydrogen 2.885 N/A LYS 139.A N ILE 128.A O no hydrogen 2.459 N/A LEU 141.A N LYS 126.A O no hydrogen 3.365 N/A ASN 142.A N GLN 147.A O no hydrogen 2.820 N/A ASN 142.A ND2 LYS 122.A O no hydrogen 3.023 N/A THR 143.A N SER 124.A O no hydrogen 2.626 N/A THR 143.A OG1 SER 124.A O no hydrogen 2.785 N/A THR 143.A OG1 SER 124.A OG no hydrogen 3.065 N/A ASN 146.A N THR 143.A O no hydrogen 3.487 N/A TYR 148.A N VAL 166.A O no hydrogen 2.826 N/A LEU 149.A N ILE 140.A O no hydrogen 2.773 N/A LEU 151.A N ARG 173.A O no hydrogen 3.333 N/A GLY 152.A N MET 162.A O no hydrogen 2.849 N/A THR 155.A OG1 ASN 156.A O no hydrogen 3.025 N/A ASN 156.A N ASP 160.A O no hydrogen 2.957 N/A ASN 156.A ND2 ASP 160.A OD2 no hydrogen 3.019 N/A ASN 158.A N ASN 156.A OD1 no hydrogen 2.758 N/A ASN 158.A ND2 ASP 160.A OD1 no hydrogen 2.635 N/A ASN 158.A ND2 ASN 217.A O no hydrogen 3.097 N/A GLY 159.A N ASN 156.A O no hydrogen 3.371 N/A ASP 160.A N ASN 156.A OD1 no hydrogen 2.893 N/A HIS 161.A N GLY 215.A O no hydrogen 2.793 N/A HIS 161.A ND1 GLY 152.A O no hydrogen 2.614 N/A ALA 163.A N ALA 213.A O no hydrogen 3.153 N/A PHE 164.A N VAL 150.A O no hydrogen 3.172 N/A GLY 165.A N ARG 109.A O no hydrogen 2.681 N/A VAL 166.A N TYR 148.A O no hydrogen 2.789 N/A ARG 173.A N SER 171.A OG no hydrogen 2.935 N/A ARG 173.A NH1 LEU 151.A O no hydrogen 3.254 N/A ALA 174.A N SER 171.A O no hydrogen 3.247 N/A TYR 176.A N TYR 191.A O no hydrogen 3.178 N/A GLN 178.A N TYR 189.A O no hydrogen 2.888 N/A GLN 178.A NE2 ASN 49.A O no hydrogen 2.468 N/A ALA 180.A N LEU 187.A O no hydrogen 2.695 N/A LYS 181.A NZ.A LYS 184.A O no hydrogen 3.025 N/A LYS 181.A NZ.B ASN 43.A OD1 no hydrogen 3.257 N/A LYS 181.A NZ.B ASN 186.A OD1 no hydrogen 2.734 N/A TYR 182.A N ASP 185.A O no hydrogen 3.240 N/A LEU 187.A N ALA 180.A O no hydrogen 2.615 N/A PHE 188.A N TRP 229.A O no hydrogen 2.837 N/A TYR 189.A N GLN 178.A O no hydrogen 2.930 N/A TYR 191.A N TYR 176.A O no hydrogen 2.772 N/A TYR 191.A OH GLN 178.A OE1 no hydrogen 2.951 N/A ASN 192.A N LYS 197.A O no hydrogen 3.017 N/A ASN 192.A ND2 ARG 173.A O no hydrogen 2.441 N/A ARG 193.A N GLN 175.A O no hydrogen 3.114 N/A ARG 193.A NH1 GLN 175.A OE1 no hydrogen 2.839 N/A ARG 193.A NH2 GLU 132.A OE1 no hydrogen 2.861 N/A GLU 194.A N PHE 172.A O no hydrogen 3.256 N/A TYR 195.A N ASN 192.A OD1 no hydrogen 3.187 N/A SER 196.A N ASN 192.A O no hydrogen 2.720 N/A LYS 197.A NZ ASN 217.A OD1 no hydrogen 2.875 N/A LEU 199.A N ILE 190.A O no hydrogen 2.952 N/A THR 200.A N TRP 214.A O no hydrogen 2.961 N/A SER 202.A N MET 212.A O no hydrogen 2.725 N/A THR 204.A N SER 202.A OG no hydrogen 3.260 N/A GLU 206.A N ASN 210.A O no hydrogen 3.164 N/A GLY 209.A N GLU 206.A O no hydrogen 2.491 N/A ARG 211.A N GLY 113.A O no hydrogen 3.091 N/A ARG 211.A NH1 SER 202.A O no hydrogen 2.900 N/A ARG 211.A NH1 ARG 203.A O no hydrogen 3.569 N/A ALA 213.A N ALA 111.A O no hydrogen 3.092 N/A TRP 214.A N THR 200.A O no hydrogen 2.877 N/A GLY 215.A N HIS 161.A O no hydrogen 2.463 N/A TYR 216.A N ALA 198.A O no hydrogen 2.752 N/A ASN 217.A N ASP 160.A OD1 no hydrogen 2.988 N/A ASN 217.A ND2 ASN 158.A O no hydrogen 2.653 N/A GLY 218.A N TYR 216.A O no hydrogen 3.208 N/A SER 223.A N VAL 220.A O no hydrogen 3.155 N/A SER 223.A OG GLU 225.A OE2 no hydrogen 3.296 N/A GLU 225.A N GLU 225.A OE1 no hydrogen 2.699 N/A TYR 227.A N SER 223.A O no hydrogen 2.676 N/A TYR 227.A N PRO 224.A O no hydrogen 2.920 N/A ALA 228.A N PRO 224.A O no hydrogen 2.901 N/A TRP 229.A N PHE 188.A O no hydrogen 2.557 N/A TRP 229.A NE1 LEU 199.A O no hydrogen 3.002 N/A GLY 230.A N MET 89.A O no hydrogen 2.693 N/A LYS 232.A N LYS 87.A O no hydrogen 3.116 N/A LYS 232.A NZ GLU 76.A OE2 no hydrogen 3.551 N/A PHE 234.A N ALA 85.A O no hydrogen 2.842 N/A