Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4eh3_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 2.A NH1 PRO 87.A O no hydrogen 3.102 N/A TYR 6.A N VAL 17.A O no hydrogen 2.978 N/A TYR 6.A OH TYR 21.A O no hydrogen 2.426 N/A GLN 8.A N TRP 15.A O no hydrogen 3.068 N/A LEU 10.A N THR 13.A O no hydrogen 2.869 N/A THR 13.A N LEU 10.A O no hydrogen 3.202 N/A THR 13.A OG1 ILE 14.A O no hydrogen 3.122 N/A TRP 15.A N GLN 8.A O no hydrogen 2.935 N/A GLU 16.A N TYR 98.A OH no hydrogen 2.919 N/A VAL 17.A N TYR 6.A O no hydrogen 3.251 N/A GLU 19.A N THR 4.A O no hydrogen 2.717 N/A ARG 20.A NE ASP 38.A OD1 no hydrogen 2.901 N/A ARG 20.A NH2 ASP 38.A OD2 no hydrogen 3.347 N/A TYR 21.A N PRO 18.A O no hydrogen 2.897 N/A TYR 21.A OH ASP 83.A OD1 no hydrogen 2.665 N/A GLN 22.A N PHE 37.A O no hydrogen 2.854 N/A GLN 22.A NE2 GLU 19.A O no hydrogen 2.760 N/A SER 25.A N ALA 35.A O no hydrogen 2.904 N/A VAL 27.A N VAL 33.A O no hydrogen 3.101 N/A SER 29.A OG GLY 28.A O no hydrogen 2.906 N/A SER 32.A N LYS 49.A O no hydrogen 3.142 N/A VAL 33.A N GLY 28.A O no hydrogen 3.390 N/A CYS 34.A N VAL 47.A O no hydrogen 2.823 N/A ALA 35.A N SER 25.A O no hydrogen 2.785 N/A ALA 36.A N VAL 45.A O no hydrogen 2.929 N/A PHE 37.A N GLN 22.A O no hydrogen 2.792 N/A ASP 38.A N LEU 43.A O no hydrogen 2.870 N/A THR 39.A N ARG 20.A O no hydrogen 3.041 N/A THR 39.A OG1 ARG 20.A O no hydrogen 3.073 N/A LYS 40.A N ASP 38.A OD1 no hydrogen 3.064 N/A THR 41.A N ASP 38.A O no hydrogen 3.205 N/A THR 41.A OG1 ASP 38.A OD2 no hydrogen 2.976 N/A GLY 42.A N ASP 38.A O no hydrogen 2.726 N/A LEU 43.A N THR 41.A OG1 no hydrogen 3.218 N/A VAL 45.A N ALA 36.A O no hydrogen 2.860 N/A ALA 46.A N THR 101.A O no hydrogen 2.798 N/A VAL 47.A N CYS 34.A O no hydrogen 2.852 N/A LYS 48.A N LEU 99.A O no hydrogen 2.798 N/A LYS 49.A N SER 32.A O no hydrogen 3.054 N/A LYS 49.A NZ THR 13.A OG1 no hydrogen 3.030 N/A LYS 49.A NZ ILE 14.A O no hydrogen 2.779 N/A LEU 50.A N VAL 97.A O no hydrogen 3.100 N/A HIS 59.A N SER 56.A OG no hydrogen 3.386 N/A HIS 59.A ND1 ARG 52.A O no hydrogen 2.713 N/A ALA 60.A N SER 56.A O no hydrogen 3.205 N/A LYS 61.A N ILE 57.A O no hydrogen 3.086 N/A LYS 61.A NZ GLU 313.A O no hydrogen 2.606 N/A LYS 61.A NZ ARG 315.A O no hydrogen 3.089 N/A ARG 62.A N ILE 58.A O no hydrogen 2.947 N/A THR 63.A N HIS 59.A O no hydrogen 2.859 N/A THR 63.A OG1 PRO 53.A O no hydrogen 2.754 N/A THR 63.A OG1 HIS 59.A O no hydrogen 2.723 N/A TYR 64.A N ALA 60.A O no hydrogen 3.139 N/A ARG 65.A N LYS 61.A O no hydrogen 2.793 N/A ARG 65.A NE GLU 313.A OE1 no hydrogen 2.767 N/A ARG 65.A NE GLU 313.A OE2 no hydrogen 3.347 N/A ARG 65.A NH2 GLU 313.A OE2 no hydrogen 2.540 N/A GLU 66.A N ARG 62.A O no hydrogen 2.916 N/A LEU 67.A N THR 63.A O no hydrogen 3.004 N/A ARG 68.A N TYR 64.A O no hydrogen 2.920 N/A ARG 68.A NH1 TYR 64.A OH no hydrogen 2.985 N/A ARG 68.A NH2 ASP 309.A O no hydrogen 2.508 N/A LEU 69.A N ARG 65.A O no hydrogen 2.921 N/A LEU 70.A N GLU 66.A O no hydrogen 3.058 N/A LYS 71.A N LEU 67.A O no hydrogen 3.073 N/A LYS 71.A NZ GLU 329.A O no hydrogen 3.138 N/A LYS 71.A NZ GLU 329.A OE1 no hydrogen 2.721 N/A LYS 71.A NZ SER 332.A OG no hydrogen 3.378 N/A HIS 72.A N ARG 68.A O no hydrogen 3.250 N/A HIS 72.A N LEU 69.A O no hydrogen 3.149 N/A HIS 72.A NE2 ASP 306.A O no hydrogen 3.183 N/A MET 73.A N LEU 69.A O no hydrogen 3.104 N/A LYS 74.A N TYR 135.A OH no hydrogen 3.035 N/A GLU 76.A N GLU 76.A OE2 no hydrogen 2.930 N/A ASN 77.A N HIS 75.A ND1 no hydrogen 3.040 N/A ASN 77.A ND2 LEU 159.A O no hydrogen 3.193 N/A VAL 78.A N HIS 75.A O no hydrogen 3.059 N/A ILE 79.A N ILE 161.A O no hydrogen 3.015 N/A LEU 82.A N VAL 100.A O no hydrogen 2.765 N/A ASP 83.A N VAL 100.A O no hydrogen 3.289 N/A PHE 85.A N TYR 98.A O no hydrogen 3.001 N/A THR 86.A OG1 ASP 96.A O no hydrogen 2.646 N/A ALA 88.A N THR 86.A OG1 no hydrogen 3.336 N/A ARG 89.A N GLU 93.A OE1 no hydrogen 3.017 N/A PHE 94.A N LEU 91.A O no hydrogen 3.056 N/A TYR 98.A N PHE 85.A O no hydrogen 3.062 N/A LEU 99.A N LYS 48.A O no hydrogen 2.869 N/A VAL 100.A N ASP 83.A O no hydrogen 2.643 N/A THR 101.A N ALA 46.A O no hydrogen 2.957 N/A THR 101.A OG1 HIS 102.A O no hydrogen 3.268 N/A ALA 106.A N VAL 153.A O no hydrogen 3.342 N/A LEU 108.A N PRO 148.A O no hydrogen 3.268 N/A LEU 108.A N LEU 151.A O no hydrogen 2.883 N/A ASN 110.A N ASP 107.A O no hydrogen 2.915 N/A ASN 110.A N ASP 107.A OD2 no hydrogen 3.228 N/A ILE 111.A N LEU 108.A O no hydrogen 3.191 N/A VAL 112.A N LEU 108.A O no hydrogen 3.263 N/A LYS 113.A N ASN 109.A O no hydrogen 3.117 N/A CYS 114.A SG ASN 110.A O no hydrogen 3.570 N/A CYS 114.A SG ILE 111.A O no hydrogen 3.256 N/A GLN 115.A N ILE 111.A O no hydrogen 3.344 N/A GLN 115.A N VAL 112.A O no hydrogen 3.243 N/A HIS 121.A N THR 118.A O no hydrogen 3.131 N/A VAL 122.A N THR 118.A O no hydrogen 3.217 N/A GLN 123.A N ASP 119.A O no hydrogen 3.181 N/A GLN 123.A NE2 GLN 295.A OE1 no hydrogen 2.863 N/A PHE 124.A N ASP 120.A O no hydrogen 3.369 N/A PHE 124.A N HIS 121.A O no hydrogen 3.275 N/A LEU 125.A N HIS 121.A O no hydrogen 3.010 N/A ILE 126.A N VAL 122.A O no hydrogen 2.734 N/A TYR 127.A N GLN 123.A O no hydrogen 2.893 N/A TYR 127.A OH GLU 302.A OE1 no hydrogen 2.447 N/A GLN 128.A N PHE 124.A O no hydrogen 3.009 N/A GLN 128.A NE2 PHE 124.A O no hydrogen 3.337 N/A GLN 128.A NE2 CYS 157.A O no hydrogen 2.830 N/A ILE 129.A N LEU 125.A O no hydrogen 3.057 N/A LEU 130.A N ILE 126.A O no hydrogen 2.892 N/A ARG 131.A N TYR 127.A O no hydrogen 2.960 N/A ARG 131.A NE ASP 301.A O no hydrogen 2.838 N/A ARG 131.A NH1 ASN 77.A OD1 no hydrogen 2.922 N/A ARG 131.A NH2 GLU 76.A OE2 no hydrogen 3.434 N/A ARG 131.A NH2 ASP 301.A O no hydrogen 3.062 N/A GLY 132.A N GLN 128.A O no hydrogen 3.041 N/A LEU 133.A N ILE 129.A O no hydrogen 2.792 N/A LYS 134.A N LEU 130.A O no hydrogen 2.801 N/A LYS 134.A NZ GLU 302.A O no hydrogen 2.802 N/A TYR 135.A N ARG 131.A O no hydrogen 3.405 N/A TYR 135.A OH HIS 72.A O no hydrogen 3.292 N/A ILE 136.A N GLY 132.A O no hydrogen 2.978 N/A HIS 137.A N LEU 133.A O no hydrogen 2.790 N/A HIS 137.A NE2 ASP 190.A OD1 no hydrogen 2.631 N/A SER 138.A N LYS 134.A O no hydrogen 3.021 N/A SER 138.A OG TYR 135.A O no hydrogen 2.880 N/A ALA 139.A N ILE 136.A O no hydrogen 3.062 N/A ASP 140.A N HIS 137.A O no hydrogen 2.949 N/A ILE 141.A N ILE 136.A O no hydrogen 3.421 N/A HIS 143.A N ASP 190.A OD1 no hydrogen 2.886 N/A ARG 144.A N ASP 190.A OD2 no hydrogen 2.949 N/A ARG 144.A NE TYR 185.A OH no hydrogen 2.691 N/A LYS 147.A NZ ASP 145.A OD1 no hydrogen 3.316 N/A LYS 147.A NZ ASP 145.A OD2 no hydrogen 3.290 N/A LYS 147.A NZ THR 170.A OG1 no hydrogen 2.987 N/A ASN 150.A N LYS 147.A O no hydrogen 2.899 N/A ASN 150.A ND2 HIS 143.A NE2 no hydrogen 3.667 N/A ASN 150.A ND2 ASP 145.A O no hydrogen 2.558 N/A LEU 151.A N PRO 148.A O no hydrogen 3.062 N/A ALA 152.A N LYS 160.A O no hydrogen 2.860 N/A VAL 153.A N ALA 106.A O no hydrogen 2.903 N/A ASN 154.A N GLU 158.A O no hydrogen 2.877 N/A ASN 154.A ND2 GLU 158.A OE2 no hydrogen 2.813 N/A GLU 155.A N GLU 155.A OE2 no hydrogen 2.495 N/A ASP 156.A N ASN 154.A OD1 no hydrogen 2.851 N/A CYS 157.A N ASN 154.A O no hydrogen 2.934 N/A GLU 158.A N ASN 154.A OD1 no hydrogen 3.091 N/A LEU 159.A N GLN 128.A OE1 no hydrogen 2.900 N/A LYS 160.A N ALA 152.A O no hydrogen 2.788 N/A LYS 160.A NZ GLU 76.A O no hydrogen 2.919 N/A ILE 161.A N ASN 77.A O no hydrogen 2.869 N/A LEU 162.A N ASN 150.A O no hydrogen 2.869 N/A GLY 165.A N ASN 150.A OD1 no hydrogen 2.809 N/A THR 170.A OG1 ASP 145.A OD2 no hydrogen 2.944 N/A ARG 171.A NH1 GLY 210.A O no hydrogen 2.861 N/A TRP 172.A N ALA 169.A O no hydrogen 3.450 N/A TRP 172.A NE1 GLY 210.A O no hydrogen 2.859 N/A TYR 173.A N THR 170.A O no hydrogen 3.327 N/A TYR 173.A OH GLU 200.A OE1 no hydrogen 2.546 N/A TYR 173.A OH GLU 200.A OE2 no hydrogen 3.424 N/A ARG 174.A N ARG 171.A O no hydrogen 3.335 N/A ARG 174.A NE ARG 144.A O no hydrogen 3.111 N/A ARG 174.A NH2 ARG 144.A O no hydrogen 2.751 N/A GLU 177.A N GLU 177.A OE2 no hydrogen 2.721 N/A ILE 178.A N ALA 175.A O no hydrogen 2.995 N/A MET 179.A N ALA 175.A O no hydrogen 3.180 N/A LEU 180.A N PRO 176.A O no hydrogen 3.007 N/A ASN 181.A N ILE 178.A O no hydrogen 3.215 N/A ASN 186.A ND2 THR 188.A OG1 no hydrogen 2.529 N/A THR 188.A OG1 SER 278.A O no hydrogen 3.321 N/A VAL 189.A N ASN 186.A O no hydrogen 3.207 N/A ASP 190.A N GLN 187.A O no hydrogen 2.979 N/A TRP 192.A N THR 188.A O no hydrogen 3.114 N/A SER 193.A N VAL 189.A O no hydrogen 3.333 N/A SER 193.A OG TYR 173.A O no hydrogen 2.857 N/A SER 193.A OG VAL 189.A O no hydrogen 3.434 N/A VAL 194.A N ASP 190.A O no hydrogen 3.124 N/A GLY 195.A N ILE 191.A O no hydrogen 2.957 N/A CYS 196.A N TRP 192.A O no hydrogen 3.193 N/A CYS 196.A SG TRP 192.A O no hydrogen 3.428 N/A ILE 197.A N SER 193.A O no hydrogen 2.769 N/A MET 198.A N VAL 194.A O no hydrogen 2.860 N/A ALA 199.A N GLY 195.A O no hydrogen 3.095 N/A GLU 200.A N CYS 196.A O no hydrogen 3.226 N/A LEU 201.A N ILE 197.A O no hydrogen 3.007 N/A LEU 202.A N MET 198.A O no hydrogen 2.938 N/A THR 203.A N ALA 199.A O no hydrogen 3.107 N/A THR 203.A OG1 ALA 199.A O no hydrogen 3.404 N/A GLY 204.A N GLU 200.A O no hydrogen 2.759 N/A ARG 205.A N THR 203.A OG1 no hydrogen 3.129 N/A GLY 210.A N PHE 208.A O no hydrogen 2.996 N/A GLY 210.A N GLN 216.A OE1 no hydrogen 3.218 N/A THR 211.A N ASP 215.A OD1 no hydrogen 2.638 N/A THR 211.A OG1 ASP 212.A OD2 no hydrogen 3.550 N/A THR 211.A OG1 ASP 215.A OD1 no hydrogen 3.199 N/A ASP 215.A N ASP 212.A OD2 no hydrogen 3.137 N/A GLN 216.A N ASP 212.A O no hydrogen 2.853 N/A GLN 216.A NE2 TRP 172.A O no hydrogen 3.648 N/A GLN 216.A NE2 PHE 208.A O no hydrogen 2.906 N/A LEU 217.A N HIS 213.A O no hydrogen 3.359 N/A LYS 218.A N ILE 214.A O no hydrogen 2.894 N/A LEU 219.A N ASP 215.A O no hydrogen 2.772 N/A ILE 220.A N GLN 216.A O no hydrogen 2.870 N/A LEU 221.A N LEU 217.A O no hydrogen 2.945 N/A ARG 222.A N LYS 218.A O no hydrogen 3.167 N/A LEU 223.A N ILE 220.A O no hydrogen 3.120 N/A VAL 224.A N ILE 220.A O no hydrogen 2.956 N/A GLY 225.A N LEU 221.A O no hydrogen 2.698 N/A THR 226.A N MET 250.A O no hydrogen 3.003 N/A THR 226.A OG1 MET 250.A O no hydrogen 3.260 N/A LEU 231.A N GLY 228.A O no hydrogen 3.256 N/A LEU 232.A N GLY 228.A O no hydrogen 2.996 N/A LYS 233.A N ALA 229.A O no hydrogen 3.110 N/A LYS 234.A N LEU 231.A O no hydrogen 2.983 N/A LYS 234.A NZ ASP 277.A OD1 no hydrogen 3.482 N/A LYS 234.A NZ ASP 277.A OD2 no hydrogen 2.802 N/A LYS 234.A NZ ASP 279.A OD1 no hydrogen 3.001 N/A ILE 235.A N LEU 232.A O no hydrogen 3.390 N/A SER 237.A OG SER 239.A OG no hydrogen 3.105 N/A SER 239.A OG SER 237.A OG no hydrogen 3.105 N/A ALA 240.A N SER 237.A OG no hydrogen 3.135 N/A ARG 241.A N SER 237.A O no hydrogen 3.155 N/A ARG 241.A NE ILE 235.A O no hydrogen 3.220 N/A ARG 241.A NH2 ILE 235.A O no hydrogen 3.374 N/A ASN 242.A N GLU 238.A O no hydrogen 2.943 N/A TYR 243.A N SER 239.A O no hydrogen 2.706 N/A ILE 244.A N ALA 240.A O no hydrogen 2.858 N/A GLN 245.A N ARG 241.A O no hydrogen 2.979 N/A SER 246.A N ASN 242.A O no hydrogen 2.688 N/A SER 246.A N TYR 243.A O no hydrogen 3.071 N/A LEU 247.A N ILE 244.A O no hydrogen 3.150 N/A LYS 252.A NZ GLU 271.A OE2 no hydrogen 3.286 N/A MET 253.A N LEU 223.A O no hydrogen 2.918 N/A ASN 257.A N ASN 254.A O no hydrogen 3.252 N/A PHE 259.A N PHE 255.A O no hydrogen 2.769 N/A ALA 262.A N PHE 259.A O no hydrogen 3.127 N/A ASN 263.A ND2 ASP 119.A OD2 no hydrogen 3.396 N/A LEU 265.A N ASN 263.A OD1 no hydrogen 2.628 N/A VAL 267.A N ASN 263.A O no hydrogen 3.075 N/A ASP 268.A N PRO 264.A O no hydrogen 3.177 N/A LEU 269.A N LEU 265.A O no hydrogen 3.021 N/A LEU 270.A N ALA 266.A O no hydrogen 3.108 N/A GLU 271.A N VAL 267.A O no hydrogen 3.066 N/A LYS 272.A N ASP 268.A O no hydrogen 3.197 N/A LYS 272.A N LEU 269.A O no hydrogen 2.784 N/A LYS 272.A NZ ASP 268.A OD1 no hydrogen 3.378 N/A LYS 272.A NZ ASP 268.A OD2 no hydrogen 3.194 N/A MET 273.A N LEU 269.A O no hydrogen 2.943 N/A MET 273.A N LEU 270.A O no hydrogen 3.285 N/A LEU 274.A N LEU 270.A O no hydrogen 2.953 N/A ASP 279.A N ASP 277.A OD1 no hydrogen 2.937 N/A LYS 280.A N ASP 277.A O no hydrogen 3.003 N/A LYS 280.A NZ GLU 230.A OE1 no hydrogen 3.032 N/A ARG 281.A NE VAL 275.A O no hydrogen 2.804 N/A ARG 281.A NH1 GLU 177.A OE1 no hydrogen 2.624 N/A ARG 281.A NH1 THR 188.A O no hydrogen 2.980 N/A ARG 281.A NH2 GLU 177.A OE1 no hydrogen 3.076 N/A ARG 281.A NH2 GLU 177.A OE2 no hydrogen 2.808 N/A ARG 281.A NH2 VAL 275.A O no hydrogen 3.165 N/A ARG 281.A NH2 LEU 276.A O no hydrogen 3.189 N/A ILE 282.A N LYS 272.A O no hydrogen 3.284 N/A THR 283.A N GLN 286.A OE1 no hydrogen 3.037 N/A THR 283.A OG1 GLN 286.A OE1 no hydrogen 3.010 N/A GLN 286.A N THR 283.A OG1 no hydrogen 3.188 N/A ALA 287.A N THR 283.A O no hydrogen 2.958 N/A LEU 288.A N ALA 284.A O no hydrogen 2.957 N/A HIS 290.A N ALA 287.A O no hydrogen 2.967 N/A HIS 290.A NE2 ASP 268.A OD2 no hydrogen 2.590 N/A TYR 292.A N HIS 290.A ND1 no hydrogen 3.142 N/A TYR 292.A OH ASP 119.A OD1 no hydrogen 3.363 N/A PHE 293.A N HIS 290.A O no hydrogen 2.944 N/A ALA 294.A N ALA 291.A O no hydrogen 2.896 N/A TYR 296.A N PHE 293.A O no hydrogen 2.765 N/A TYR 296.A OH ASP 120.A OD2 no hydrogen 2.823 N/A HIS 297.A N PHE 293.A O no hydrogen 2.921 N/A ASP 298.A N GLU 302.A OE1 no hydrogen 3.268 N/A ASP 300.A N ASP 298.A OD1 no hydrogen 2.902 N/A ASP 301.A N ASP 298.A O no hydrogen 2.772 N/A ALA 305.A N SER 138.A OG no hydrogen 2.770 N/A SER 311.A N ASP 309.A OD1 no hydrogen 2.976 N/A SER 311.A OG ASP 309.A OD1 no hydrogen 2.734 N/A GLU 313.A N GLN 310.A O no hydrogen 2.910 N/A SER 314.A N SER 311.A O no hydrogen 3.154 N/A SER 314.A OG SER 311.A O no hydrogen 3.080 N/A ARG 315.A N PHE 312.A O no hydrogen 2.900 N/A LEU 318.A N GLU 321.A OE1 no hydrogen 2.956 N/A GLU 321.A N LEU 318.A O no hydrogen 2.793 N/A TRP 322.A N LEU 318.A O no hydrogen 3.044 N/A LYS 323.A N ILE 319.A O no hydrogen 2.884 N/A LYS 323.A NZ PHE 94.A O no hydrogen 3.171 N/A SER 324.A N ASP 320.A O no hydrogen 3.100 N/A LEU 325.A N GLU 321.A O no hydrogen 2.955 N/A THR 326.A N TRP 322.A O no hydrogen 2.909 N/A THR 326.A OG1 TRP 322.A O no hydrogen 2.816 N/A TYR 327.A N LYS 323.A O no hydrogen 2.946 N/A ASP 328.A N SER 324.A O no hydrogen 3.043 N/A GLU 329.A N LEU 325.A O no hydrogen 3.135 N/A VAL 330.A N THR 326.A O no hydrogen 3.039 N/A ILE 331.A N TYR 327.A O no hydrogen 3.061 N/A SER 332.A N ASP 328.A O no hydrogen 3.033 N/A SER 332.A OG ASP 328.A O no hydrogen 3.048 N/A PHE 333.A N VAL 330.A O no hydrogen 3.040 N/A