Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4en2_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 1.A NE GLY 47.A O no hydrogen 3.176 N/A ARG 1.A NH1 PRO 98.A O no hydrogen 2.796 N/A ARG 1.A NH2 GLY 47.A O no hydrogen 3.298 N/A SER 2.A OG GLU 3.A O no hydrogen 3.191 N/A GLY 4.A N GLU 3.A OE2 no hydrogen 3.407 N/A TYR 7.A N SER 46.A OG no hydrogen 2.740 N/A TYR 7.A OH ASP 100.A OD1 no hydrogen 3.031 N/A TYR 7.A OH ASP 100.A OD2 no hydrogen 2.393 N/A GLU 11.A N PHE 44.A O no hydrogen 2.737 N/A VAL 12.A N LEU 238.A O no hydrogen 2.893 N/A PHE 13.A N ARG 42.A O no hydrogen 2.973 N/A LEU 14.A N TRP 240.A O no hydrogen 2.674 N/A ASP 15.A N LYS 40.A O no hydrogen 2.766 N/A VAL 16.A N ARG 242.A O no hydrogen 2.856 N/A ILE 17.A N SER 38.A O no hydrogen 2.920 N/A GLU 18.A N ILE 244.A O no hydrogen 2.869 N/A ALA 19.A N VAL 36.A O no hydrogen 2.741 N/A VAL 20.A N GLN 246.A O no hydrogen 2.903 N/A ASN 21.A N GLU 34.A O no hydrogen 2.744 N/A ASN 21.A ND2 GLU 34.A OE1 no hydrogen 3.188 N/A LEU 22.A N ASP 249.A O no hydrogen 2.928 N/A LEU 23.A N ARG 32.A O no hydrogen 2.757 N/A VAL 24.A N GLN 251.A O no hydrogen 2.990 N/A SER 25.A N ASN 29.A O no hydrogen 2.750 N/A GLY 28.A N SER 25.A O no hydrogen 2.552 N/A ASN 29.A N ASN 27.A OD1 no hydrogen 2.788 N/A LEU 31.A N LEU 23.A O no hydrogen 2.625 N/A ARG 32.A N LEU 23.A O no hydrogen 3.085 N/A ARG 32.A NH1 GLU 34.A OE1 no hydrogen 2.891 N/A SER 33.A OG VAL 114.A O no hydrogen 3.010 N/A GLU 34.A N ASN 21.A O no hydrogen 2.990 N/A ILE 35.A N LEU 110.A O no hydrogen 2.990 N/A VAL 36.A N ALA 19.A O no hydrogen 2.856 N/A GLY 37.A N TYR 108.A O no hydrogen 2.848 N/A SER 38.A N ILE 17.A O no hydrogen 2.769 N/A SER 38.A OG GLU 104.A OE1 no hydrogen 3.322 N/A ILE 39.A N MET 106.A O no hydrogen 2.887 N/A LYS 40.A N ASP 15.A O no hydrogen 2.857 N/A MET 41.A N PHE 103.A O no hydrogen 2.721 N/A ARG 42.A N PHE 13.A O no hydrogen 2.887 N/A VAL 43.A N GLY 101.A O no hydrogen 2.890 N/A PHE 44.A N GLU 11.A O no hydrogen 2.700 N/A SER 46.A N ASN 10.A OD1 no hydrogen 2.901 N/A SER 46.A OG TYR 7.A O no hydrogen 3.217 N/A SER 46.A OG ASN 10.A OD1 no hydrogen 2.534 N/A GLY 47.A N ILE 5.A O no hydrogen 2.613 N/A MET 48.A N GLU 231.A OE2 no hydrogen 3.031 N/A GLU 50.A N ILE 230.A O no hydrogen 3.109 N/A LEU 51.A N PHE 96.A O no hydrogen 2.790 N/A ARG 52.A N LYS 228.A O no hydrogen 2.844 N/A LEU 53.A N ILE 94.A O no hydrogen 2.961 N/A GLY 54.A N TYR 226.A O no hydrogen 2.727 N/A ASN 56.A N GLN 223.A O no hydrogen 3.329 N/A ASN 56.A ND2 LYS 70.A O no hydrogen 3.659 N/A ASN 56.A ND2 GLY 221.A O no hydrogen 2.900 N/A ASP 57.A N LEU 55.A O no hydrogen 2.657 N/A LYS 58.A N VAL 72.A O no hydrogen 2.931 N/A LYS 58.A NZ ASP 62.A OD1 no hydrogen 3.345 N/A LYS 58.A NZ ASP 62.A OD2 no hydrogen 2.544 N/A VAL 59.A N ASP 57.A OD1 no hydrogen 2.841 N/A PHE 61.A N ASP 57.A O no hydrogen 2.999 N/A ASP 62.A N LYS 58.A O no hydrogen 2.742 N/A ASN 63.A N VAL 59.A O no hydrogen 2.962 N/A THR 64.A N PHE 61.A O no hydrogen 2.967 N/A THR 64.A OG1 LEU 60.A O no hydrogen 2.768 N/A THR 64.A OG1 PHE 61.A O no hydrogen 3.441 N/A ARG 66.A N PHE 61.A O no hydrogen 2.794 N/A ARG 66.A NE THR 64.A OG1 no hydrogen 2.785 N/A ARG 66.A NH2 THR 64.A OG1 no hydrogen 2.849 N/A SER 69.A N ARG 66.A O no hydrogen 2.892 N/A LYS 70.A NZ SER 71.A O no hydrogen 3.125 N/A LYS 70.A NZ SER 220.A O no hydrogen 2.362 N/A VAL 72.A N ASN 56.A O no hydrogen 2.833 N/A GLU 75.A N ARG 109.A O no hydrogen 2.887 N/A ASP 76.A N GLU 75.A OE2 no hydrogen 3.169 N/A LYS 78.A N SER 107.A O no hydrogen 2.831 N/A HIS 80.A N LEU 105.A O no hydrogen 2.729 N/A CYS 82.A N HIS 80.A ND1 no hydrogen 3.266 N/A CYS 82.A SG HIS 80.A ND1 no hydrogen 3.561 N/A VAL 83.A N HIS 80.A O no hydrogen 3.239 N/A ARG 84.A N SER 95.A O no hydrogen 2.881 N/A ARG 84.A NH1 GLU 50.A OE2 no hydrogen 2.626 N/A ARG 84.A NH2 GLU 50.A OE1 no hydrogen 2.876 N/A ARG 84.A NH2 GLU 50.A OE2 no hydrogen 3.250 N/A PHE 88.A N ARG 84.A O no hydrogen 3.272 N/A GLU 89.A N LEU 85.A O no hydrogen 2.647 N/A ASN 90.A N SER 86.A O no hydrogen 2.658 N/A ASP 91.A N ARG 87.A O no hydrogen 3.043 N/A ARG 92.A N PHE 88.A O no hydrogen 2.797 N/A ARG 92.A NH1 ASP 57.A OD1 no hydrogen 2.995 N/A ARG 92.A NH1 ASP 57.A OD2 no hydrogen 2.744 N/A THR 93.A N ARG 87.A O no hydrogen 3.282 N/A THR 93.A N ASP 91.A OD1 no hydrogen 3.089 N/A THR 93.A OG1 ASP 91.A OD1 no hydrogen 2.732 N/A THR 93.A OG1 ASP 91.A OD2 no hydrogen 3.149 N/A SER 95.A OG GLU 50.A OE2 no hydrogen 3.133 N/A PHE 96.A N LEU 51.A O no hydrogen 3.018 N/A GLY 101.A N VAL 43.A O no hydrogen 3.069 N/A PHE 103.A N MET 41.A O no hydrogen 2.877 N/A LEU 105.A N ILE 39.A O no hydrogen 2.823 N/A SER 107.A N LYS 78.A O no hydrogen 2.887 N/A TYR 108.A N GLY 37.A O no hydrogen 2.992 N/A TYR 108.A OH GLU 18.A OE1 no hydrogen 2.682 N/A ARG 109.A N GLU 75.A O no hydrogen 2.843 N/A ARG 109.A NE GLU 34.A OE2 no hydrogen 3.110 N/A ARG 109.A NH1 ASP 76.A OD1 no hydrogen 2.355 N/A ARG 109.A NH2 GLU 34.A OE2 no hydrogen 3.065 N/A LEU 110.A N ILE 35.A O no hydrogen 2.985 N/A THR 112.A OG1 HIS 113.A ND1 no hydrogen 3.258 N/A ILE 118.A N TYR 250.A OH no hydrogen 2.799 N/A TRP 119.A N LYS 139.A O no hydrogen 2.815 N/A GLU 121.A N LYS 137.A O no hydrogen 2.969 N/A VAL 123.A N MET 135.A O no hydrogen 2.708 N/A GLU 125.A N GLU 133.A O no hydrogen 2.686 N/A HIS 127.A N ARG 131.A O no hydrogen 3.240 N/A SER 130.A N SER 128.A O no hydrogen 2.522 N/A ILE 132.A N PHE 201.A O no hydrogen 3.426 N/A GLU 133.A N GLU 125.A O no hydrogen 2.950 N/A TYR 134.A N ALA 199.A O no hydrogen 2.614 N/A MET 135.A N VAL 123.A O no hydrogen 2.687 N/A VAL 136.A N MET 197.A O no hydrogen 2.731 N/A LYS 137.A N GLU 121.A O no hydrogen 2.708 N/A LYS 137.A NZ GLU 121.A OE2 no hydrogen 3.447 N/A LYS 137.A NZ GLU 194.A OE2 no hydrogen 3.293 N/A ALA 138.A N TYR 195.A O no hydrogen 2.830 N/A LYS 139.A N TRP 119.A O no hydrogen 2.825 N/A SER 140.A N LYS 193.A O no hydrogen 2.914 N/A SER 140.A OG PRO 190.A O no hydrogen 2.601 N/A SER 140.A OG LYS 193.A O no hydrogen 3.424 N/A GLN 141.A N LEU 117.A O no hydrogen 2.612 N/A GLN 141.A NE2 PRO 116.A O no hydrogen 2.841 N/A SER 146.A N LYS 143.A O no hydrogen 2.920 N/A ALA 148.A N PHE 189.A O no hydrogen 2.875 N/A ASN 149.A N GLU 213.A O no hydrogen 2.686 N/A ASN 150.A N LYS 187.A O no hydrogen 2.808 N/A VAL 151.A N VAL 186.A O no hydrogen 3.016 N/A GLU 152.A N LYS 211.A O no hydrogen 2.820 N/A ILE 153.A N TRP 184.A O no hydrogen 2.689 N/A HIS 154.A N SER 209.A O no hydrogen 2.713 N/A HIS 154.A ND1 GLU 181.A OE2 no hydrogen 3.295 N/A HIS 154.A NE2 GLU 152.A OE1 no hydrogen 2.731 N/A ILE 155.A N ILE 182.A O no hydrogen 2.571 N/A VAL 157.A N SER 180.A O no hydrogen 3.111 N/A ASP 162.A N GLY 202.A O no hydrogen 2.626 N/A SER 163.A OG ASP 162.A O no hydrogen 2.340 N/A LYS 165.A N HIS 200.A O no hydrogen 2.416 N/A LYS 167.A N ARG 198.A O no hydrogen 2.653 N/A THR 169.A N LEU 196.A O no hydrogen 3.191 N/A SER 172.A N SER 185.A O no hydrogen 2.836 N/A LYS 174.A N VAL 183.A O no hydrogen 3.055 N/A VAL 176.A N GLU 181.A O no hydrogen 2.845 N/A GLU 178.A N GLU 178.A OE2 no hydrogen 2.571 N/A SER 180.A N PRO 177.A O no hydrogen 2.725 N/A SER 180.A OG VAL 157.A O no hydrogen 3.084 N/A GLU 181.A N VAL 176.A O no hydrogen 2.905 N/A ILE 182.A N ILE 155.A O no hydrogen 2.606 N/A VAL 183.A N LYS 174.A O no hydrogen 2.992 N/A TRP 184.A N ILE 153.A O no hydrogen 2.803 N/A TRP 184.A NE1 VAL 170.A O no hydrogen 2.952 N/A SER 185.A N SER 172.A O no hydrogen 2.759 N/A VAL 186.A N VAL 151.A O no hydrogen 2.874 N/A LYS 187.A NZ ASN 150.A OD1 no hydrogen 3.006 N/A PHE 189.A N ALA 148.A O no hydrogen 2.841 N/A GLY 191.A N SER 146.A O no hydrogen 2.797 N/A GLY 192.A N SER 140.A O no hydrogen 2.922 N/A LYS 193.A N SER 140.A OG no hydrogen 2.752 N/A TYR 195.A N ALA 138.A O no hydrogen 2.821 N/A MET 197.A N VAL 136.A O no hydrogen 2.818 N/A ARG 198.A N LYS 167.A O no hydrogen 2.747 N/A ALA 199.A N TYR 134.A O no hydrogen 2.793 N/A HIS 200.A N LYS 165.A O no hydrogen 2.918 N/A PHE 201.A N ILE 132.A O no hydrogen 3.230 N/A GLY 202.A N ASP 162.A O no hydrogen 2.555 N/A LEU 203.A N SER 130.A O no hydrogen 2.285 N/A LYS 205.A NZ PRO 156.A O no hydrogen 3.473 N/A SER 209.A N HIS 154.A O no hydrogen 3.086 N/A VAL 210.A N TYR 250.A O no hydrogen 3.072 N/A LYS 211.A N GLU 152.A O no hydrogen 2.779 N/A PHE 212.A N ASN 247.A OD1 no hydrogen 2.952 N/A GLU 213.A N ASN 149.A O no hydrogen 3.187 N/A ILE 214.A N THR 245.A O no hydrogen 2.660 N/A PHE 217.A N TYR 243.A O no hydrogen 3.093 N/A THR 219.A N GLU 18.A OE2 no hydrogen 3.371 N/A SER 220.A N GLU 18.A OE2 no hydrogen 3.367 N/A SER 220.A OG GLU 18.A OE1 no hydrogen 2.602 N/A SER 220.A OG GLU 18.A OE2 no hydrogen 3.123 N/A GLY 221.A N THR 218.A OG1 no hydrogen 3.115 N/A ILE 222.A N SER 220.A OG no hydrogen 3.130 N/A GLN 223.A N ASN 56.A OD1 no hydrogen 2.751 N/A VAL 224.A N TYR 243.A OH no hydrogen 3.041 N/A ARG 225.A N GLY 54.A O no hydrogen 2.642 N/A TYR 226.A N GLY 54.A O no hydrogen 3.324 N/A LYS 228.A N ARG 52.A O no hydrogen 2.830 N/A ILE 230.A N GLU 50.A O no hydrogen 2.802 N/A LYS 232.A NZ MET 48.A O no hydrogen 3.283 N/A LYS 232.A NZ ILE 230.A O no hydrogen 3.243 N/A SER 233.A OG GLU 231.A OE1 no hydrogen 3.058 N/A LEU 238.A N ASN 10.A O no hydrogen 3.107 N/A TRP 240.A N VAL 12.A O no hydrogen 2.688 N/A ARG 242.A N LEU 14.A O no hydrogen 2.925 N/A ARG 242.A NE ASP 15.A OD1 no hydrogen 3.307 N/A ARG 242.A NE ASP 15.A OD2 no hydrogen 2.955 N/A ARG 242.A NH2 ASP 15.A OD2 no hydrogen 2.916 N/A ILE 244.A N VAL 16.A O no hydrogen 2.810 N/A THR 245.A N ILE 214.A O no hydrogen 2.869 N/A THR 245.A OG1 PHE 217.A O no hydrogen 3.087 N/A GLN 246.A N GLU 18.A O no hydrogen 2.821 N/A ASN 247.A N PHE 212.A O no hydrogen 3.104 N/A ASN 247.A ND2 GLY 248.A O no hydrogen 3.008 N/A GLY 248.A N VAL 20.A O no hydrogen 2.748 N/A ASP 249.A N ASN 21.A OD1 no hydrogen 2.881 N/A TYR 250.A OH ILE 118.A O no hydrogen 2.404 N/A GLN 251.A N LEU 22.A O no hydrogen 2.742 N/A LEU 252.A N ILE 208.A O no hydrogen 2.680 N/A ARG 253.A N VAL 24.A O no hydrogen 2.892 N/A