Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4eoh_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 3.A N ASP 75.A OD2 no hydrogen 2.823 N/A ARG 3.A NH2 GLU 1.A OE1 no hydrogen 3.256 N/A VAL 4.A N GLU 31.A O no hydrogen 3.024 N/A LEU 5.A N TYR 76.A O no hydrogen 2.995 N/A SER 6.A N ASP 33.A O no hydrogen 2.902 N/A SER 6.A OG GLN 8.A OE1 no hydrogen 3.033 N/A ILE 7.A N LEU 78.A O no hydrogen 2.902 N/A GLN 8.A N ASN 18.A OD1 no hydrogen 3.224 N/A GLN 8.A N VAL 35.A O no hydrogen 3.017 N/A HIS 10.A N VAL 38.A O no hydrogen 2.846 N/A ILE 12.A N PHE 40.A O no hydrogen 2.860 N/A ARG 13.A N SER 41.A O no hydrogen 3.027 N/A TYR 15.A N GLU 281.A OE1 no hydrogen 3.012 N/A GLY 17.A N ASP 226.A OD1 no hydrogen 2.641 N/A ASN 18.A N SER 9.A O no hydrogen 2.784 N/A ASN 18.A ND2 SER 6.A O no hydrogen 3.580 N/A ASN 18.A ND2 SER 6.A OG no hydrogen 2.501 N/A ARG 19.A N VAL 16.A O no hydrogen 2.949 N/A ARG 19.A NE GLY 14.A O no hydrogen 3.093 N/A ALA 20.A N GLY 17.A O no hydrogen 2.918 N/A ALA 21.A N GLY 17.A O no hydrogen 3.100 N/A THR 22.A N ASN 18.A O no hydrogen 2.943 N/A THR 22.A OG1 ASN 18.A O no hydrogen 2.758 N/A LEU 25.A N ALA 21.A O no hydrogen 3.427 N/A GLN 26.A N THR 22.A O no hydrogen 2.826 N/A VAL 27.A N PHE 23.A O no hydrogen 2.797 N/A LEU 28.A N PRO 24.A O no hydrogen 3.018 N/A GLY 29.A N GLN 26.A O no hydrogen 2.760 N/A PHE 30.A N LEU 25.A O no hydrogen 2.878 N/A GLU 31.A N CYS 2.A O no hydrogen 2.946 N/A ASP 33.A N VAL 4.A O no hydrogen 2.715 N/A VAL 35.A N SER 6.A O no hydrogen 2.908 N/A ASN 36.A ND2 ASN 18.A OD1 no hydrogen 3.460 N/A SER 37.A N GLN 8.A O no hydrogen 2.762 N/A GLN 39.A N GLN 52.A O no hydrogen 3.023 N/A PHE 40.A N HIS 10.A O no hydrogen 2.958 N/A SER 41.A N LYS 50.A O no hydrogen 2.899 N/A GLY 45.A N HIS 43.A ND1 no hydrogen 2.721 N/A TYR 46.A N HIS 43.A O no hydrogen 3.482 N/A TYR 46.A OH GLU 281.A OE2 no hydrogen 2.567 N/A LYS 50.A N SER 41.A OG no hydrogen 3.377 N/A GLN 52.A N GLN 39.A O no hydrogen 3.071 N/A LEU 54.A N SER 37.A O no hydrogen 2.796 N/A ASN 55.A N GLU 58.A OE1 no hydrogen 2.934 N/A GLU 58.A N ASN 55.A OD1 no hydrogen 2.817 N/A LEU 59.A N ASN 55.A O no hydrogen 3.093 N/A GLN 60.A N SER 56.A O no hydrogen 3.150 N/A GLU 61.A N ASP 57.A O no hydrogen 3.034 N/A LEU 62.A N GLU 58.A O no hydrogen 3.027 N/A TYR 63.A N LEU 59.A O no hydrogen 3.015 N/A GLU 64.A N GLN 60.A O no hydrogen 2.820 N/A GLY 65.A N GLU 61.A O no hydrogen 2.997 N/A LEU 66.A N LEU 62.A O no hydrogen 3.403 N/A ARG 67.A N TYR 63.A O no hydrogen 2.828 N/A LEU 68.A N GLU 64.A O no hydrogen 2.793 N/A ASN 69.A N GLY 65.A O no hydrogen 3.243 N/A ASN 69.A ND2 GLY 65.A O no hydrogen 3.136 N/A ASN 70.A N ARG 67.A O no hydrogen 2.779 N/A MET 71.A N LEU 66.A O no hydrogen 2.751 N/A ASN 72.A ND2 TYR 63.A OH no hydrogen 3.500 N/A LYS 73.A NZ ASN 70.A O no hydrogen 3.533 N/A LYS 73.A NZ GLN 101.A OE1 no hydrogen 3.561 N/A TYR 74.A OH ASP 33.A OD2 no hydrogen 2.624 N/A ASP 75.A N ARG 3.A O no hydrogen 3.024 N/A TYR 76.A N ARG 3.A O no hydrogen 3.062 N/A TYR 76.A OH HIS 237.A ND1 no hydrogen 2.647 N/A VAL 77.A N VAL 106.A O no hydrogen 3.120 N/A LEU 78.A N LEU 5.A O no hydrogen 2.811 N/A THR 79.A N VAL 108.A O no hydrogen 3.204 N/A THR 79.A OG1 TYR 107.A OH no hydrogen 2.745 N/A THR 82.A OG1 GLY 80.A O no hydrogen 3.081 N/A ARG 83.A NH1 TYR 81.A OH no hydrogen 3.156 N/A LEU 88.A N ASP 84.A O no hydrogen 3.011 N/A ALA 89.A N LYS 85.A O no hydrogen 2.893 N/A MET 90.A N SER 86.A O no hydrogen 2.901 N/A VAL 91.A N PHE 87.A O no hydrogen 2.854 N/A VAL 92.A N LEU 88.A O no hydrogen 2.997 N/A ASP 93.A N ALA 89.A O no hydrogen 3.161 N/A ILE 94.A N MET 90.A O no hydrogen 3.061 N/A VAL 95.A N VAL 91.A O no hydrogen 2.940 N/A GLN 96.A N VAL 92.A O no hydrogen 2.706 N/A GLU 97.A N ASP 93.A O no hydrogen 3.012 N/A LEU 98.A N ILE 94.A O no hydrogen 2.759 N/A LYS 99.A N VAL 95.A O no hydrogen 2.734 N/A LYS 99.A NZ LEU 105.A O no hydrogen 3.125 N/A LYS 99.A NZ ASP 142.A OD1 no hydrogen 2.932 N/A GLN 100.A N GLN 96.A O no hydrogen 2.978 N/A GLN 101.A N GLU 97.A O no hydrogen 2.705 N/A ASN 102.A N LEU 98.A O no hydrogen 2.750 N/A ASN 102.A ND2 TYR 74.A O no hydrogen 2.937 N/A ARG 104.A N ASN 102.A OD1 no hydrogen 3.219 N/A LEU 105.A N ASN 102.A O no hydrogen 2.937 N/A VAL 106.A N ASP 75.A O no hydrogen 2.967 N/A TYR 107.A N ASP 142.A OD1 no hydrogen 2.813 N/A TYR 107.A OH THR 79.A OG1 no hydrogen 2.745 N/A VAL 108.A N VAL 77.A O no hydrogen 2.843 N/A CYS 109.A N ILE 143.A O no hydrogen 2.729 N/A ASP 110.A N THR 79.A O no hydrogen 3.015 N/A VAL 112.A N ASP 110.A O no hydrogen 2.889 N/A LEU 113.A N GLU 150.A OE2 no hydrogen 2.998 N/A ASP 115.A N SER 122.A O no hydrogen 2.941 N/A LYS 116.A NZ GLU 152.A OE1 no hydrogen 2.815 N/A LYS 116.A NZ GLU 152.A OE2 no hydrogen 3.342 N/A SER 122.A N ASP 115.A O no hydrogen 2.847 N/A SER 122.A OG ASP 115.A O no hydrogen 2.980 N/A TYR 124.A N LEU 113.A O no hydrogen 2.651 N/A LEU 129.A N PRO 126.A O no hydrogen 3.196 N/A TYR 133.A N LEU 129.A O no hydrogen 2.907 N/A LYS 134.A N LEU 130.A O no hydrogen 2.925 N/A GLU 135.A N PRO 131.A O no hydrogen 2.841 N/A LYS 136.A N VAL 132.A O no hydrogen 2.831 N/A VAL 137.A N VAL 132.A O no hydrogen 3.007 N/A VAL 138.A N TYR 133.A O no hydrogen 2.798 N/A LEU 140.A N VAL 137.A O no hydrogen 2.731 N/A ALA 141.A N VAL 137.A O no hydrogen 3.053 N/A ALA 141.A N VAL 138.A O no hydrogen 3.025 N/A ASP 142.A N TYR 107.A O no hydrogen 2.916 N/A ILE 143.A N TYR 107.A O no hydrogen 3.223 N/A ILE 144.A N THR 179.A O no hydrogen 3.086 N/A THR 145.A N CYS 109.A O no hydrogen 3.218 N/A THR 145.A OG1 ASP 110.A OD1 no hydrogen 2.681 N/A ASN 147.A N GLU 150.A OE1 no hydrogen 2.736 N/A ASN 147.A ND2 GLY 114.A O no hydrogen 2.776 N/A GLN 148.A N SER 184.A O no hydrogen 2.728 N/A GLU 150.A N ASN 147.A OD1 no hydrogen 2.643 N/A ALA 151.A N ASN 147.A O no hydrogen 3.103 N/A GLU 152.A N GLN 148.A O no hydrogen 3.028 N/A LEU 153.A N PHE 149.A O no hydrogen 3.063 N/A LEU 154.A N GLU 150.A O no hydrogen 2.949 N/A SER 155.A N ALA 151.A O no hydrogen 3.029 N/A SER 155.A OG ALA 151.A O no hydrogen 2.957 N/A SER 155.A OG GLU 152.A O no hydrogen 3.345 N/A GLY 156.A N GLU 152.A O no hydrogen 2.608 N/A ARG 157.A N SER 155.A OG no hydrogen 3.186 N/A ILE 159.A N GLU 152.A OE2 no hydrogen 3.060 N/A HIS 160.A N GLU 164.A OE1 no hydrogen 2.584 N/A HIS 160.A ND1 GLU 164.A OE1 no hydrogen 2.699 N/A SER 161.A OG GLU 163.A OE2 no hydrogen 3.183 N/A ALA 165.A N SER 161.A O no hydrogen 3.003 N/A LEU 166.A N GLN 162.A O no hydrogen 2.940 N/A ARG 167.A N GLU 163.A O no hydrogen 3.088 N/A VAL 168.A N GLU 164.A O no hydrogen 3.043 N/A MET 169.A N ALA 165.A O no hydrogen 2.960 N/A ASP 170.A N LEU 166.A O no hydrogen 2.946 N/A MET 171.A N ARG 167.A O no hydrogen 3.059 N/A LEU 172.A N VAL 168.A O no hydrogen 2.919 N/A HIS 173.A N MET 169.A O no hydrogen 2.943 N/A HIS 173.A ND1 PRO 177.A O no hydrogen 2.747 N/A HIS 173.A NE2 SER 201.A OG no hydrogen 2.975 N/A SER 174.A N ASP 170.A O no hydrogen 3.100 N/A SER 174.A OG MET 171.A O no hydrogen 2.520 N/A MET 175.A N MET 171.A O no hydrogen 3.108 N/A GLY 176.A N LEU 172.A O no hydrogen 3.185 N/A GLY 176.A N HIS 173.A O no hydrogen 2.866 N/A THR 179.A N ASP 142.A O no hydrogen 3.027 N/A VAL 180.A N SER 201.A O no hydrogen 2.846 N/A VAL 181.A N ILE 144.A O no hydrogen 3.174 N/A ILE 182.A N LEU 199.A O no hydrogen 2.673 N/A THR 183.A N PRO 146.A O no hydrogen 3.237 N/A SER 185.A OG ILE 197.A O no hydrogen 2.978 N/A ASP 186.A N GLN 148.A OE1 no hydrogen 2.632 N/A LEU 187.A N SER 185.A OG no hydrogen 3.278 N/A SER 189.A OG ASP 213.A OD1 no hydrogen 2.645 N/A GLN 191.A N SER 189.A OG no hydrogen 3.057 N/A GLY 192.A N SER 189.A O no hydrogen 3.117 N/A TYR 195.A N GLY 192.A O no hydrogen 3.262 N/A LEU 196.A N ILE 214.A O no hydrogen 2.681 N/A VAL 198.A N MET 212.A O no hydrogen 2.806 N/A LEU 199.A N ILE 182.A O no hydrogen 3.198 N/A GLY 200.A N ILE 210.A O no hydrogen 3.123 N/A SER 201.A N VAL 180.A O no hydrogen 2.721 N/A SER 201.A OG HIS 173.A NE2 no hydrogen 2.975 N/A GLN 202.A N GLU 208.A O no hydrogen 2.801 N/A GLN 202.A NE2 THR 179.A OG1 no hydrogen 2.634 N/A ARG 203.A N ASP 178.A O no hydrogen 2.718 N/A ARG 203.A NE ASP 178.A OD1 no hydrogen 2.700 N/A ARG 203.A NH1 HIS 173.A O no hydrogen 3.363 N/A ARG 203.A NH2 HIS 173.A O no hydrogen 3.094 N/A ARG 203.A NH2 ASP 178.A OD1 no hydrogen 2.624 N/A ARG 204.A N VAL 206.A O no hydrogen 2.951 N/A ARG 204.A NH1 GLN 202.A OE1 no hydrogen 2.684 N/A ARG 204.A NH1 GLU 208.A OE2 no hydrogen 2.616 N/A ARG 204.A NH2 GLU 208.A OE2 no hydrogen 2.720 N/A VAL 206.A N ARG 204.A O no hydrogen 2.638 N/A GLU 208.A N GLN 202.A O no hydrogen 2.870 N/A ARG 209.A NH2 ASP 170.A OD1 no hydrogen 2.730 N/A ARG 209.A NH2 ASP 170.A OD2 no hydrogen 3.283 N/A ILE 210.A N GLY 200.A O no hydrogen 2.872 N/A ARG 211.A N THR 301.A O no hydrogen 2.873 N/A MET 212.A N VAL 198.A O no hydrogen 2.942 N/A ILE 214.A N LEU 196.A O no hydrogen 2.815 N/A LYS 216.A N ASN 194.A O no hydrogen 2.780 N/A LYS 216.A NZ SER 193.A O no hydrogen 3.482 N/A ALA 219.A N VAL 217.A O no hydrogen 2.801 N/A LEU 227.A N GLY 223.A O no hydrogen 2.900 N/A PHE 228.A N THR 224.A O no hydrogen 2.816 N/A ALA 229.A N GLY 225.A O no hydrogen 3.039 N/A ALA 230.A N ASP 226.A O no hydrogen 3.206 N/A MET 231.A N LEU 227.A O no hydrogen 2.928 N/A LEU 232.A N PHE 228.A O no hydrogen 2.801 N/A LEU 233.A N ALA 229.A O no hydrogen 2.949 N/A ALA 234.A N ALA 230.A O no hydrogen 2.964 N/A TRP 235.A N MET 231.A O no hydrogen 2.826 N/A THR 236.A N LEU 232.A O no hydrogen 2.852 N/A THR 236.A OG1 LEU 232.A O no hydrogen 2.671 N/A THR 236.A OG1 LEU 233.A O no hydrogen 3.084 N/A HIS 237.A N LEU 233.A O no hydrogen 3.028 N/A HIS 237.A ND1 TYR 76.A OH no hydrogen 2.647 N/A LYS 238.A N ALA 234.A O no hydrogen 3.150 N/A LYS 238.A NZ LEU 28.A O no hydrogen 3.421 N/A HIS 239.A N TRP 235.A O no hydrogen 2.835 N/A ASN 242.A N HIS 239.A O no hydrogen 3.288 N/A LEU 243.A N GLU 208.A OE2 no hydrogen 3.012 N/A LYS 244.A N GLU 208.A OE1 no hydrogen 3.203 N/A LYS 244.A NZ GLU 248.A OE2 no hydrogen 2.910 N/A VAL 245.A N ASN 242.A OD1 no hydrogen 2.785 N/A ALA 246.A N ASN 242.A O no hydrogen 3.179 N/A CYS 247.A N LEU 243.A O no hydrogen 2.979 N/A CYS 247.A SG LEU 243.A O no hydrogen 3.369 N/A GLU 248.A N LYS 244.A O no hydrogen 3.064 N/A LYS 249.A N VAL 245.A O no hydrogen 2.968 N/A THR 250.A N ALA 246.A O no hydrogen 3.073 N/A THR 250.A OG1 ALA 246.A O no hydrogen 2.609 N/A VAL 251.A N CYS 247.A O no hydrogen 2.917 N/A SER 252.A N GLU 248.A O no hydrogen 2.821 N/A SER 252.A OG GLU 248.A O no hydrogen 2.685 N/A THR 253.A N LYS 249.A O no hydrogen 2.867 N/A THR 253.A OG1 LYS 249.A O no hydrogen 2.770 N/A LEU 254.A N THR 250.A O no hydrogen 3.147 N/A HIS 255.A N VAL 251.A O no hydrogen 2.913 N/A HIS 256.A N SER 252.A O no hydrogen 3.101 N/A HIS 256.A NE2 GLU 295.A O no hydrogen 2.844 N/A VAL 257.A N THR 253.A O no hydrogen 3.125 N/A LEU 258.A N LEU 254.A O no hydrogen 2.828 N/A GLN 259.A N HIS 255.A O no hydrogen 2.770 N/A ARG 260.A N HIS 256.A O no hydrogen 3.072 N/A ARG 260.A NH1 ASP 290.A OD2 no hydrogen 2.616 N/A ARG 260.A NH2 ASP 290.A OD2 no hydrogen 2.939 N/A THR 261.A N VAL 257.A O no hydrogen 2.904 N/A THR 261.A OG1 VAL 257.A O no hydrogen 2.626 N/A ILE 262.A N LEU 258.A O no hydrogen 2.782 N/A GLN 263.A N GLN 259.A O no hydrogen 3.165 N/A CYS 264.A N ARG 260.A O no hydrogen 3.193 N/A CYS 264.A SG ARG 260.A O no hydrogen 3.182 N/A ALA 265.A N THR 261.A O no hydrogen 2.987 N/A LYS 266.A N ILE 262.A O no hydrogen 3.098 N/A ALA 267.A N GLN 263.A O no hydrogen 2.996 N/A GLN 268.A N CYS 264.A O no hydrogen 3.069 N/A ALA 269.A N ALA 265.A O no hydrogen 2.915 N/A VAL 273.A N GLY 270.A O no hydrogen 2.950 N/A SER 276.A N GLN 279.A OE1 no hydrogen 2.831 N/A SER 276.A OG GLN 279.A OE1 no hydrogen 3.497 N/A GLN 279.A N SER 276.A OG no hydrogen 3.385 N/A LEU 280.A N SER 276.A O no hydrogen 3.005 N/A GLU 281.A N MET 278.A O no hydrogen 3.478 N/A ARG 283.A N THR 261.A OG1 no hydrogen 3.015 N/A ARG 283.A NH1 GLN 279.A O no hydrogen 3.181 N/A ARG 283.A NH2 GLN 279.A O no hydrogen 3.327 N/A GLN 286.A N GLN 286.A OE1 no hydrogen 2.609 N/A SER 287.A N MET 284.A O no hydrogen 2.938 N/A SER 287.A OG ARG 283.A O no hydrogen 2.757 N/A LYS 288.A N VAL 285.A O no hydrogen 3.392 N/A ILE 291.A N SER 287.A O no hydrogen 2.992 N/A GLU 292.A N LYS 288.A O no hydrogen 3.024 N/A ASP 293.A N ARG 289.A O no hydrogen 3.146 N/A VAL 297.A N SER 252.A OG no hydrogen 3.040 N/A ALA 300.A N GLU 248.A OE2 no hydrogen 2.802 N/A THR 301.A N ARG 211.A O no hydrogen 2.880 N/A THR 301.A OG1 ARG 211.A O no hydrogen 3.239 N/A LEU 303.A N ARG 209.A O no hydrogen 2.817 N/A