Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4er5_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 4.A N TYR 17.A O no hydrogen 2.800 N/A ARG 5.A NH1 GLU 3.A OE2 no hydrogen 3.295 N/A LEU 6.A N ALA 15.A O no hydrogen 2.857 N/A LYS 7.A N ASN 70.A OD1 no hydrogen 2.812 N/A LYS 7.A NZ ASP 74.A OD1 no hydrogen 2.681 N/A LYS 7.A NZ ASP 74.A OD2 no hydrogen 2.838 N/A SER 8.A OG TRP 199.A O no hydrogen 2.738 N/A VAL 10.A N SER 8.A OG no hydrogen 3.034 N/A GLY 11.A N SER 8.A O no hydrogen 3.298 N/A ALA 12.A N SER 8.A OG no hydrogen 3.175 N/A ALA 15.A N LEU 6.A O no hydrogen 2.824 N/A TYR 17.A N LEU 4.A O no hydrogen 2.791 N/A TYR 17.A OH GLU 33.A OE2 no hydrogen 2.581 N/A TRP 19.A N LEU 2.A O no hydrogen 3.051 N/A TYR 24.A N HIS 28.A O no hydrogen 2.819 N/A TYR 24.A OH GLU 33.A OE1 no hydrogen 3.391 N/A ASP 25.A N HIS 28.A O no hydrogen 3.057 N/A HIS 27.A N ASP 25.A OD1 no hydrogen 2.661 N/A HIS 28.A N ASP 25.A OD1 no hydrogen 3.105 N/A ALA 30.A N PRO 22.A O no hydrogen 2.742 N/A HIS 32.A N ASP 29.A OD1 no hydrogen 3.025 N/A HIS 32.A ND1 ASP 29.A OD1 no hydrogen 2.878 N/A GLU 33.A N ASP 29.A O no hydrogen 3.157 N/A ILE 34.A N ALA 30.A O no hydrogen 2.908 N/A ILE 35.A N ALA 31.A O no hydrogen 3.104 N/A GLU 36.A N HIS 32.A O no hydrogen 2.819 N/A THR 37.A N GLU 33.A O no hydrogen 2.816 N/A THR 37.A OG1 GLU 33.A O no hydrogen 2.686 N/A THR 37.A OG1 HIS 100.A NE2 no hydrogen 3.028 N/A ILE 38.A N ILE 34.A O no hydrogen 2.986 N/A ARG 39.A N ILE 35.A O no hydrogen 3.033 N/A TRP 40.A N GLU 36.A O no hydrogen 2.931 N/A VAL 41.A N THR 37.A O no hydrogen 2.887 N/A CYS 42.A N ILE 38.A O no hydrogen 3.051 N/A CYS 42.A SG ILE 38.A O no hydrogen 3.339 N/A GLU 43.A N ARG 39.A O no hydrogen 3.224 N/A GLU 43.A N TRP 40.A O no hydrogen 2.942 N/A GLU 44.A N TRP 40.A O no hydrogen 3.059 N/A ILE 45.A N VAL 41.A O no hydrogen 3.125 N/A LYS 49.A N ILE 45.A O no hydrogen 3.157 N/A LEU 50.A N PRO 46.A O no hydrogen 2.811 N/A ALA 51.A N ASP 47.A O no hydrogen 3.010 N/A MET 52.A N LEU 48.A O no hydrogen 3.052 N/A MET 52.A N LYS 49.A O no hydrogen 3.271 N/A ASP 55.A N SER 61.A OG no hydrogen 3.214 N/A LYS 57.A N ASP 55.A OD1 no hydrogen 3.312 N/A SER 58.A N ASP 55.A O no hydrogen 3.301 N/A SER 61.A N SER 58.A OG no hydrogen 3.231 N/A SER 61.A OG ASP 55.A O no hydrogen 3.511 N/A MET 62.A N SER 58.A O no hydrogen 3.204 N/A GLN 63.A N PHE 59.A O no hydrogen 2.685 N/A ARG 64.A N GLU 60.A O no hydrogen 2.821 N/A LEU 65.A N SER 61.A O no hydrogen 3.303 N/A CYS 66.A N MET 62.A O no hydrogen 3.009 N/A CYS 66.A SG MET 62.A O no hydrogen 3.348 N/A ASP 67.A N GLN 63.A O no hydrogen 2.826 N/A LYS 68.A N ARG 64.A O no hydrogen 3.163 N/A TYR 69.A N LEU 65.A O no hydrogen 3.060 N/A TYR 69.A OH LYS 7.A O no hydrogen 2.677 N/A ASN 70.A N CYS 66.A O no hydrogen 2.768 N/A ASN 70.A ND2 ARG 5.A O no hydrogen 2.918 N/A ARG 71.A N ASP 67.A O no hydrogen 2.863 N/A ALA 72.A N LYS 68.A O no hydrogen 3.173 N/A ILE 73.A N TYR 69.A O no hydrogen 2.926 N/A ASP 74.A N ASN 70.A O no hydrogen 3.045 N/A SER 75.A N ARG 71.A O no hydrogen 3.023 N/A SER 75.A OG ALA 72.A O no hydrogen 2.837 N/A ILE 76.A N ALA 72.A O no hydrogen 3.085 N/A HIS 77.A N ILE 73.A O no hydrogen 2.962 N/A HIS 77.A NE2 PRO 9.A O no hydrogen 2.902 N/A GLN 78.A N ASP 74.A O no hydrogen 3.126 N/A LEU 79.A N SER 75.A O no hydrogen 3.068 N/A TRP 80.A N ILE 76.A O no hydrogen 3.050 N/A LYS 81.A N HIS 77.A O no hydrogen 3.136 N/A GLY 82.A N GLN 78.A O no hydrogen 3.295 N/A THR 91.A OG1 ARG 92.A O no hydrogen 3.525 N/A ARG 92.A NH1 ALA 166.A O no hydrogen 2.847 N/A ARG 92.A NH1 THR 168.A O no hydrogen 2.804 N/A ARG 92.A NH2 THR 168.A O no hydrogen 3.110 N/A LEU 97.A N SER 94.A OG no hydrogen 3.301 N/A LEU 98.A N SER 94.A O no hydrogen 2.914 N/A ARG 99.A N THR 95.A O no hydrogen 2.888 N/A ARG 99.A NH1 ASP 133.A OD1 no hydrogen 2.675 N/A HIS 100.A N GLY 96.A O no hydrogen 3.279 N/A HIS 100.A NE2 THR 37.A OG1 no hydrogen 3.028 N/A ILE 101.A N LEU 97.A O no hydrogen 2.774 N/A LEU 102.A N LEU 98.A O no hydrogen 2.881 N/A GLN 103.A N ARG 99.A O no hydrogen 3.054 N/A GLN 103.A NE2 GLN 103.A O no hydrogen 3.276 N/A GLN 103.A NE2 ASN 107.A OD1 no hydrogen 3.144 N/A GLN 104.A N HIS 100.A O no hydrogen 2.905 N/A GLN 104.A NE2 GLU 33.A OE2 no hydrogen 3.037 N/A GLN 104.A NE2 THR 37.A OG1 no hydrogen 3.199 N/A VAL 105.A N ILE 101.A O no hydrogen 2.832 N/A TYR 106.A N LEU 102.A O no hydrogen 2.911 N/A ASN 107.A N GLN 103.A O no hydrogen 2.808 N/A ASN 107.A ND2 GLU 33.A OE1 no hydrogen 2.978 N/A HIS 108.A N GLN 104.A O no hydrogen 3.143 N/A HIS 108.A NE2 GLU 33.A OE2 no hydrogen 2.774 N/A SER 109.A N TYR 106.A O no hydrogen 3.166 N/A SER 109.A OG VAL 105.A O no hydrogen 2.715 N/A VAL 110.A N TYR 106.A O no hydrogen 2.949 N/A ASP 112.A N TYR 185.A OH no hydrogen 3.456 N/A GLU 114.A N ASP 112.A OD1 no hydrogen 3.255 N/A LYS 115.A N ASP 112.A O no hydrogen 3.066 N/A ASN 118.A ND2 PHE 122.A O no hydrogen 3.295 N/A PHE 122.A N TYR 119.A O no hydrogen 2.991 N/A GLU 129.A N VAL 126.A O no hydrogen 3.321 N/A PHE 132.A N GLY 128.A O no hydrogen 2.762 N/A LEU 134.A N THR 130.A O no hydrogen 2.904 N/A VAL 135.A N SER 131.A O no hydrogen 3.004 N/A ALA 136.A N PHE 132.A O no hydrogen 2.955 N/A GLN 137.A N ASP 133.A O no hydrogen 2.842 N/A GLN 137.A NE2 GLU 141.A OE1 no hydrogen 2.668 N/A GLN 137.A NE2 SER 288.A O no hydrogen 2.674 N/A MET 138.A N LEU 134.A O no hydrogen 2.981 N/A ILE 139.A N VAL 135.A O no hydrogen 2.790 N/A ASP 140.A N ALA 136.A O no hydrogen 3.208 N/A GLU 141.A N GLN 137.A O no hydrogen 2.989 N/A ILE 142.A N MET 138.A O no hydrogen 2.898 N/A THR 145.A N ASP 148.A OD2 no hydrogen 3.098 N/A ASP 148.A N THR 145.A O no hydrogen 3.081 N/A LEU 149.A N SER 227.A OG no hydrogen 3.075 N/A PHE 150.A N HIS 172.A O no hydrogen 3.060 N/A VAL 151.A N VAL 228.A O no hydrogen 2.975 N/A ASP 152.A N TYR 174.A O no hydrogen 2.945 N/A LEU 153.A N PHE 230.A O no hydrogen 3.042 N/A GLY 154.A N VAL 176.A O no hydrogen 3.020 N/A SER 155.A N VAL 176.A O no hydrogen 3.018 N/A GLY 156.A N GLU 177.A OE1 no hydrogen 2.686 N/A GLY 158.A N SER 155.A O no hydrogen 2.790 N/A GLN 159.A N GLN 159.A OE1 no hydrogen 2.585 N/A LEU 162.A N GLY 158.A O no hydrogen 3.046 N/A GLN 163.A N GLN 159.A O no hydrogen 3.346 N/A GLN 163.A NE2 PHE 132.A O no hydrogen 2.936 N/A VAL 164.A N VAL 160.A O no hydrogen 2.916 N/A ALA 165.A N VAL 161.A O no hydrogen 2.780 N/A ALA 166.A N LEU 162.A O no hydrogen 2.862 N/A ALA 167.A N GLN 163.A O no hydrogen 3.106 N/A ALA 167.A N VAL 164.A O no hydrogen 3.173 N/A THR 168.A N VAL 164.A O no hydrogen 2.987 N/A THR 168.A OG1 VAL 164.A O no hydrogen 3.276 N/A CYS 170.A SG THR 168.A OG1 no hydrogen 3.579 N/A LYS 171.A N ASP 148.A O no hydrogen 2.879 N/A HIS 172.A NE2 THR 208.A OG1 no hydrogen 2.765 N/A HIS 173.A N GLU 206.A O no hydrogen 3.032 N/A HIS 173.A ND1 GLU 206.A O no hydrogen 2.921 N/A HIS 173.A NE2 THR 168.A OG1 no hydrogen 2.748 N/A TYR 174.A N PHE 150.A O no hydrogen 2.801 N/A GLY 175.A N THR 208.A O no hydrogen 3.056 N/A VAL 176.A N ASP 152.A O no hydrogen 3.445 N/A GLU 177.A N GLU 210.A O no hydrogen 3.049 N/A LYS 178.A N GLU 177.A OE2 no hydrogen 2.806 N/A ALA 179.A N GLU 177.A OE2 no hydrogen 2.882 N/A ALA 183.A N ALA 179.A O no hydrogen 3.153 N/A LYS 184.A N ASP 180.A O no hydrogen 2.868 N/A TYR 185.A N ILE 181.A O no hydrogen 3.149 N/A ALA 186.A N PRO 182.A O no hydrogen 2.946 N/A GLU 187.A N ALA 183.A O no hydrogen 3.211 N/A MET 189.A N TYR 185.A O no hydrogen 2.758 N/A ASP 190.A N ALA 186.A O no hydrogen 2.945 N/A ARG 191.A N GLU 187.A O no hydrogen 3.469 N/A GLU 192.A N THR 188.A O no hydrogen 2.851 N/A PHE 193.A N MET 189.A O no hydrogen 2.767 N/A ARG 194.A N ASP 190.A O no hydrogen 3.010 N/A ARG 194.A NE.A ASP 190.A OD1 no hydrogen 3.401 N/A ARG 194.A NH1.B ASP 190.A OD1 no hydrogen 2.615 N/A ARG 194.A NH2.A ASP 190.A OD2 no hydrogen 3.411 N/A LYS 195.A N ARG 191.A O no hydrogen 3.067 N/A LYS 195.A NZ GLU 192.A OE1 no hydrogen 3.106 N/A LYS 195.A NZ GLU 192.A OE2 no hydrogen 3.461 N/A TRP 196.A N GLU 192.A O no hydrogen 2.846 N/A TRP 196.A NE1 GLU 192.A OE1 no hydrogen 3.083 N/A MET 197.A N PHE 193.A O no hydrogen 3.011 N/A LYS 198.A N ARG 194.A O no hydrogen 3.092 N/A TRP 199.A N LYS 195.A O no hydrogen 2.932 N/A TYR 200.A N TRP 196.A O no hydrogen 3.076 N/A TYR 200.A OH GLN 104.A OE1 no hydrogen 2.700 N/A GLY 201.A N MET 197.A O no hydrogen 2.938 N/A GLY 201.A N LYS 198.A O no hydrogen 3.035 N/A LYS 202.A N MET 197.A O no hydrogen 2.951 N/A LYS 202.A NZ THR 91.A OG1 no hydrogen 2.757 N/A LYS 203.A N THR 91.A O no hydrogen 2.837 N/A HIS 204.A ND1 ALA 205.A O no hydrogen 2.746 N/A ALA 205.A N ALA 165.A O no hydrogen 2.898 N/A TYR 207.A OH ASP 190.A OD1 no hydrogen 2.461 N/A THR 208.A N HIS 173.A O no hydrogen 2.825 N/A THR 208.A OG1 HIS 172.A NE2 no hydrogen 2.765 N/A GLU 210.A N GLY 175.A O no hydrogen 2.809 N/A ARG 211.A NE LYS 178.A O no hydrogen 3.013 N/A ARG 211.A NH1 LYS 178.A O no hydrogen 3.393 N/A GLY 212.A N GLU 177.A O no hydrogen 2.802 N/A LEU 215.A N ASP 213.A OD1 no hydrogen 2.788 N/A SER 216.A N ASP 213.A O no hydrogen 3.076 N/A SER 216.A OG ASP 213.A O no hydrogen 2.626 N/A TRP 219.A N SER 216.A O no hydrogen 3.014 N/A ARG 220.A N GLU 217.A O no hydrogen 3.035 N/A ARG 222.A NH1 GLU 210.A OE2 no hydrogen 2.913 N/A ARG 222.A NH2 GLU 210.A OE1 no hydrogen 2.883 N/A ILE 223.A N TRP 219.A O no hydrogen 2.795 N/A ALA 224.A N ARG 220.A O no hydrogen 3.096 N/A ASN 225.A N GLU 221.A O no hydrogen 3.059 N/A ASN 225.A N ARG 222.A O no hydrogen 3.230 N/A THR 226.A N ILE 223.A O no hydrogen 3.080 N/A THR 226.A OG1 ARG 222.A O no hydrogen 2.633 N/A SER 227.A N LEU 149.A O no hydrogen 3.220 N/A SER 227.A OG ASP 148.A OD1 no hydrogen 2.599 N/A SER 227.A OG LEU 149.A O no hydrogen 3.402 N/A VAL 228.A N LEU 149.A O no hydrogen 3.025 N/A ILE 229.A N ARG 256.A O no hydrogen 2.838 N/A PHE 230.A N VAL 151.A O no hydrogen 2.867 N/A VAL 231.A N VAL 258.A O no hydrogen 2.999 N/A ASN 232.A ND2 GLU 120.A O no hydrogen 3.021 N/A ASN 233.A ND2 ASP 241.A OD1 no hydrogen 3.352 N/A ASN 233.A ND2 LYS 261.A O no hydrogen 2.864 N/A PHE 234.A N SER 260.A OG no hydrogen 2.914 N/A PHE 236.A N ASN 233.A O no hydrogen 2.947 N/A ASP 241.A N GLY 237.A O no hydrogen 3.120 N/A HIS 242.A N PRO 238.A O no hydrogen 3.130 N/A GLN 243.A N GLU 239.A O no hydrogen 3.085 N/A LEU 244.A N VAL 240.A O no hydrogen 3.082 N/A LYS 245.A N ASP 241.A O no hydrogen 3.061 N/A GLU 246.A N HIS 242.A O no hydrogen 3.239 N/A ARG 247.A N GLN 243.A O no hydrogen 3.256 N/A ARG 247.A NH1 GLN 243.A O no hydrogen 2.964 N/A ARG 247.A NH1 GLN 243.A OE1 no hydrogen 2.753 N/A ARG 247.A NH2 LEU 215.A O no hydrogen 2.670 N/A PHE 248.A N LEU 244.A O no hydrogen 2.785 N/A ALA 249.A N LYS 245.A O no hydrogen 3.009 N/A ASN 250.A N ARG 247.A O no hydrogen 3.183 N/A MET 251.A N PHE 248.A O no hydrogen 2.985 N/A GLY 254.A N ILE 305.A O no hydrogen 2.962 N/A GLY 255.A N LYS 252.A O no hydrogen 2.992 N/A ARG 256.A N SER 227.A O no hydrogen 2.803 N/A ARG 256.A NH1 LYS 143.A O no hydrogen 3.018 N/A ARG 256.A NH2 LYS 143.A O no hydrogen 2.956 N/A ILE 257.A N HIS 303.A O no hydrogen 2.974 N/A VAL 258.A N ILE 229.A O no hydrogen 2.853 N/A SER 259.A N TYR 301.A O no hydrogen 2.906 N/A SER 259.A OG LYS 261.A O no hydrogen 2.606 N/A SER 260.A N ASN 233.A OD1 no hydrogen 3.152 N/A SER 260.A OG ASN 232.A OD1 no hydrogen 2.709 N/A SER 260.A OG ASN 233.A OD1 no hydrogen 3.295 N/A LYS 261.A N ASN 233.A OD1 no hydrogen 2.856 N/A LYS 261.A NZ ASN 233.A O no hydrogen 3.344 N/A LYS 261.A NZ PHE 234.A O no hydrogen 3.448 N/A LYS 261.A NZ ASP 241.A OD2 no hydrogen 2.707 N/A PHE 263.A N HIS 303.A NE2 no hydrogen 2.972 N/A ASN 267.A N ASN 267.A OD1.B no hydrogen 2.636 N/A ASN 271.A N ASN 274.A OD1 no hydrogen 2.800 N/A ARG 273.A N ASN 271.A OD1 no hydrogen 2.861 N/A ASN 274.A N ASN 271.A OD1 no hydrogen 3.316 N/A ASN 274.A ND2 ARG 269.A O no hydrogen 2.750 N/A ASP 277.A N ASN 274.A O no hydrogen 3.279 N/A THR 280.A N ASP 277.A O no hydrogen 3.024 N/A THR 280.A OG1 ASP 277.A O no hydrogen 2.705 N/A ILE 281.A N ILE 278.A O no hydrogen 3.081 N/A ARG 283.A N THR 304.A O no hydrogen 2.957 N/A ARG 283.A NH2 ASP 306.A OD2 no hydrogen 3.035 N/A VAL 285.A N LEU 302.A O no hydrogen 2.960 N/A LEU 287.A N TYR 300.A O no hydrogen 2.792 N/A SER 293.A OG LEU 290.A O no hydrogen 3.285 N/A SER 293.A OG GLY 292.A O no hydrogen 2.681 N/A SER 299.A OG TYR 301.A OH no hydrogen 2.949 N/A TYR 301.A N SER 259.A O no hydrogen 2.817 N/A TYR 301.A OH SER 299.A OG no hydrogen 2.949 N/A LEU 302.A N VAL 285.A O no hydrogen 2.938 N/A HIS 303.A N ILE 257.A O no hydrogen 2.803 N/A HIS 303.A ND1 ILE 257.A O no hydrogen 2.925 N/A THR 304.A N ARG 283.A O no hydrogen 2.866 N/A ILE 305.A N GLY 255.A O no hydrogen 2.878 N/A ASP 306.A N ILE 281.A O no hydrogen 2.783 N/A ARG 307.A N GLU 253.A OE1 no hydrogen 2.587 N/A ARG 307.A NH1 MET 251.A O no hydrogen 2.934 N/A ARG 307.A NH1 GLU 253.A OE2 no hydrogen 3.462 N/A ARG 307.A NH2 ALA 249.A O no hydrogen 3.019 N/A ARG 307.A NH2 MET 251.A O no hydrogen 2.776 N/A THR 308.A N ASP 306.A OD1 no hydrogen 3.264 N/A THR 308.A OG1 ASP 306.A OD1 no hydrogen 2.638 N/A THR 308.A OG1 ASP 306.A OD2 no hydrogen 3.461 N/A LEU 310.A N ARG 307.A O no hydrogen 3.168 N/A GLU 311.A N ARG 307.A O no hydrogen 3.028 N/A ASN 312.A N THR 308.A O no hydrogen 2.970 N/A TYR 313.A N ILE 309.A O no hydrogen 3.379 N/A PHE 314.A N LEU 310.A O no hydrogen 3.104 N/A SER 315.A N GLU 311.A O no hydrogen 2.935 N/A SER 315.A OG GLU 311.A O no hydrogen 3.213 N/A SER 316.A N ASN 312.A O no hydrogen 2.842 N/A SER 316.A OG TYR 313.A O no hydrogen 2.623 N/A LEU 317.A N TYR 313.A O no hydrogen 3.122 N/A LYS 318.A N SER 315.A O no hydrogen 3.124 N/A ASN 319.A N SER 316.A O no hydrogen 3.167 N/A LYS 321.A N ASN 319.A OD1 no hydrogen 3.252 N/A ARG 323.A N ASN 319.A O no hydrogen 2.800 N/A ARG 323.A NE LEU 317.A O no hydrogen 3.201 N/A GLU 324.A N PRO 320.A O no hydrogen 3.076 N/A GLU 325.A N LYS 321.A O no hydrogen 3.108 N/A GLN 326.A N LEU 322.A O no hydrogen 3.095 N/A GLU 327.A N ARG 323.A O no hydrogen 3.114 N/A ALA 328.A N GLU 325.A O no hydrogen 2.658 N/A