Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4f1o_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 5.A N LEU 80.A O no hydrogen 2.892 N/A ALA 6.A N GLU 9.A OE1 no hydrogen 2.811 N/A GLU 9.A N ALA 6.A O no hydrogen 2.940 N/A GLU 11.A N ARG 28.A O no hydrogen 2.864 N/A GLU 13.A N LYS 26.A O no hydrogen 2.866 N/A LYS 14.A N LYS 26.A O no hydrogen 3.262 N/A ILE 16.A N VAL 24.A O no hydrogen 2.973 N/A LEU 23.A N SER 40.A OG no hydrogen 3.168 N/A HIS 25.A N ILE 38.A O no hydrogen 2.768 N/A LYS 26.A N LYS 14.A O no hydrogen 2.679 N/A GLY 27.A N VAL 36.A O no hydrogen 2.731 N/A ARG 28.A N GLU 11.A O no hydrogen 2.945 N/A ARG 28.A NE GLU 13.A OE2 no hydrogen 3.061 N/A LEU 29.A N SER 34.A O no hydrogen 2.944 N/A VAL 30.A N GLU 9.A O no hydrogen 2.869 N/A VAL 36.A N GLY 27.A O no hydrogen 2.740 N/A ALA 37.A N MET 89.A O no hydrogen 2.633 N/A ILE 38.A N HIS 25.A O no hydrogen 2.662 N/A LYS 39.A N MET 87.A O no hydrogen 2.849 N/A LYS 39.A NZ GLU 62.A OE1 no hydrogen 3.550 N/A LYS 39.A NZ GLU 62.A OE2 no hydrogen 2.782 N/A LYS 39.A NZ ASP 161.A OD1 no hydrogen 3.213 N/A SER 40.A N LEU 23.A O no hydrogen 2.803 N/A SER 40.A OG LEU 23.A O no hydrogen 2.935 N/A LEU 41.A N PRO 85.A O no hydrogen 2.771 N/A ILE 42.A N PHE 21.A O no hydrogen 2.986 N/A GLU 47.A N GLY 44.A O no hydrogen 3.072 N/A GLY 48.A N GLY 44.A O no hydrogen 3.308 N/A ILE 53.A N GLU 49.A O no hydrogen 2.996 N/A GLU 54.A N GLU 51.A O no hydrogen 3.408 N/A LYS 55.A N MET 52.A O no hydrogen 3.260 N/A LYS 55.A NZ ILE 42.A O no hydrogen 3.250 N/A LYS 55.A NZ GLU 47.A OE1 no hydrogen 3.326 N/A PHE 59.A N LYS 55.A O no hydrogen 3.211 N/A GLN 60.A N PHE 56.A O no hydrogen 2.861 N/A ARG 61.A N GLN 57.A O no hydrogen 2.760 N/A GLU 62.A N GLU 58.A O no hydrogen 2.934 N/A VAL 63.A N PHE 59.A O no hydrogen 3.128 N/A PHE 64.A N GLN 60.A O no hydrogen 2.964 N/A ILE 65.A N ARG 61.A O no hydrogen 3.056 N/A MET 66.A N GLU 62.A O no hydrogen 2.800 N/A SER 67.A N VAL 63.A O no hydrogen 3.027 N/A SER 67.A OG VAL 63.A O no hydrogen 3.433 N/A SER 67.A OG PHE 64.A O no hydrogen 2.738 N/A ASN 68.A N ILE 65.A O no hydrogen 3.376 N/A LEU 69.A N MET 66.A O no hydrogen 3.247 N/A ASN 70.A N TYR 126.A OH no hydrogen 2.939 N/A ASN 73.A ND2 ALA 157.A O no hydrogen 3.211 N/A ILE 74.A N HIS 71.A O no hydrogen 3.050 N/A VAL 75.A N VAL 159.A O no hydrogen 3.056 N/A LYS 76.A N GLU 90.A OE2 no hydrogen 2.998 N/A TYR 78.A N VAL 88.A O no hydrogen 2.679 N/A LEU 80.A N PRO 3.A O no hydrogen 2.900 N/A MET 81.A N ARG 86.A O no hydrogen 2.893 N/A ARG 86.A N MET 81.A O no hydrogen 2.937 N/A ARG 86.A NE PRO 84.A O no hydrogen 2.896 N/A ARG 86.A NH1 ASP 7.A OD1 no hydrogen 3.221 N/A ARG 86.A NH1 TYR 12.A OH no hydrogen 3.015 N/A ARG 86.A NH2 ASP 7.A OD1 no hydrogen 2.928 N/A ARG 86.A NH2 HIS 82.A O no hydrogen 2.776 N/A MET 87.A N LYS 39.A O no hydrogen 2.789 N/A VAL 88.A N GLY 79.A O no hydrogen 3.076 N/A MET 89.A N ALA 37.A O no hydrogen 2.755 N/A GLU 90.A N LYS 76.A O no hydrogen 2.972 N/A PHE 91.A N VAL 35.A O no hydrogen 3.393 N/A CYS 94.A N LEU 146.A O no hydrogen 2.958 N/A CYS 94.A SG GLN 147.A O no hydrogen 3.501 N/A LEU 97.A N ILE 144.A O no hydrogen 2.830 N/A TYR 98.A N SER 141.A O no hydrogen 3.124 N/A HIS 99.A N ASP 96.A OD2 no hydrogen 3.087 N/A ARG 100.A N ASP 96.A O no hydrogen 3.304 N/A ARG 100.A NH1 ARG 100.A O no hydrogen 2.780 N/A ARG 100.A NH1 HIS 106.A O no hydrogen 2.850 N/A ARG 100.A NH2 HIS 106.A O no hydrogen 2.820 N/A LEU 101.A N LEU 97.A O no hydrogen 3.150 N/A LEU 102.A N HIS 99.A O no hydrogen 3.325 N/A ASP 103.A N ARG 100.A O no hydrogen 3.289 N/A LYS 104.A N LEU 102.A O no hydrogen 2.946 N/A LYS 104.A NZ GLU 214.A OE2 no hydrogen 3.102 N/A HIS 106.A ND1 ASP 103.A OD1 no hydrogen 3.323 N/A HIS 106.A ND1 ASP 103.A OD2 no hydrogen 3.145 N/A LYS 109.A NZ GLU 151.A OE2 no hydrogen 3.223 N/A SER 111.A OG GLU 151.A OE1 no hydrogen 2.708 N/A VAL 112.A N LYS 109.A O no hydrogen 2.920 N/A LYS 113.A N LYS 109.A O no hydrogen 3.093 N/A LYS 113.A NZ LEU 211.A O no hydrogen 3.091 N/A LEU 114.A N TRP 110.A O no hydrogen 3.142 N/A ARG 115.A N SER 111.A O no hydrogen 3.226 N/A ARG 115.A NH1 GLU 151.A O no hydrogen 2.729 N/A ARG 115.A NH1 ALA 153.A O no hydrogen 2.674 N/A ARG 115.A NH2 ASP 119.A OD1 no hydrogen 3.416 N/A ARG 115.A NH2 ALA 153.A O no hydrogen 3.068 N/A ARG 115.A NH2 PRO 154.A O no hydrogen 3.115 N/A LEU 116.A N VAL 112.A O no hydrogen 2.959 N/A MET 117.A N LYS 113.A O no hydrogen 2.859 N/A LEU 118.A N LEU 114.A O no hydrogen 2.862 N/A ASP 119.A N ARG 115.A O no hydrogen 2.835 N/A ILE 120.A N LEU 116.A O no hydrogen 3.060 N/A ALA 121.A N MET 117.A O no hydrogen 3.048 N/A LEU 122.A N LEU 118.A O no hydrogen 2.872 N/A GLY 123.A N ASP 119.A O no hydrogen 3.173 N/A ILE 124.A N ILE 120.A O no hydrogen 2.930 N/A GLU 125.A N ALA 121.A O no hydrogen 2.819 N/A TYR 126.A N LEU 122.A O no hydrogen 3.023 N/A MET 127.A N GLY 123.A O no hydrogen 3.098 N/A GLN 128.A N ILE 124.A O no hydrogen 2.929 N/A GLN 128.A NE2 THR 200.A OG1 no hydrogen 3.317 N/A ASN 129.A N GLU 125.A O no hydrogen 3.005 N/A ASN 129.A N TYR 126.A O no hydrogen 3.248 N/A GLN 130.A N MET 127.A O no hydrogen 3.381 N/A ILE 134.A N MET 127.A O no hydrogen 2.851 N/A VAL 135.A N GLN 166.A O no hydrogen 2.935 N/A HIS 136.A N ASP 199.A OD2 no hydrogen 2.609 N/A HIS 136.A NE2 ALA 160.A O no hydrogen 2.817 N/A ARG 137.A N ASP 199.A OD1 no hydrogen 3.128 N/A ASP 138.A N HIS 136.A ND1 no hydrogen 3.173 N/A ARG 140.A NE ASP 138.A OD1 no hydrogen 2.879 N/A ARG 140.A NE ASP 138.A OD2 no hydrogen 3.181 N/A ARG 140.A NH2 ASP 138.A OD2 no hydrogen 3.107 N/A ASN 143.A N ARG 140.A O no hydrogen 2.819 N/A ASN 143.A ND2 ASP 138.A O no hydrogen 2.772 N/A ASN 143.A ND2 ASP 138.A OD2 no hydrogen 2.898 N/A ILE 144.A N SER 141.A O no hydrogen 3.355 N/A PHE 145.A N LYS 158.A O no hydrogen 2.822 N/A LEU 146.A N GLY 95.A O no hydrogen 2.789 N/A GLN 147.A N CYS 156.A O no hydrogen 2.758 N/A SER 148.A N CYS 156.A O no hydrogen 3.285 N/A ASP 150.A N SER 148.A OG no hydrogen 2.974 N/A ASN 152.A N ASP 150.A OD2 no hydrogen 3.382 N/A ALA 153.A N ASP 150.A O no hydrogen 3.156 N/A CYS 156.A N ASP 119.A OD2 no hydrogen 2.695 N/A CYS 156.A SG ASP 150.A O no hydrogen 3.269 N/A ALA 157.A N ASP 119.A OD2 no hydrogen 2.989 N/A LYS 158.A N PHE 145.A O no hydrogen 2.743 N/A LYS 158.A NZ PRO 72.A O no hydrogen 2.614 N/A LYS 158.A NZ GLU 90.A OE2 no hydrogen 3.311 N/A VAL 159.A N ASN 73.A O no hydrogen 2.835 N/A ALA 160.A N ASN 143.A O no hydrogen 2.945 N/A SER 165.A N PHE 162.A O no hydrogen 3.429 N/A SER 165.A OG VAL 135.A O no hydrogen 2.694 N/A GLN 166.A N VAL 135.A O no hydrogen 2.702 N/A GLN 167.A NE2 PRO 132.A O no hydrogen 2.818 N/A HIS 170.A N SER 168.A OG no hydrogen 3.227 N/A VAL 172.A N TYR 194.A O no hydrogen 3.340 N/A LEU 176.A N THR 186.A O no hydrogen 3.058 N/A ASN 178.A ND2 GLN 180.A OE1 no hydrogen 2.852 N/A TRP 181.A N ASN 178.A O no hydrogen 3.131 N/A MET 182.A N PHE 179.A O no hydrogen 3.442 N/A GLU 185.A N GLU 185.A OE1 no hydrogen 2.892 N/A THR 186.A N ALA 183.A O no hydrogen 2.953 N/A THR 186.A OG1 ALA 183.A O no hydrogen 2.662 N/A TYR 194.A N VAL 172.A O no hydrogen 2.671 N/A TYR 194.A OH GLY 174.A O no hydrogen 2.814 N/A GLU 196.A N GLU 196.A OE2 no hydrogen 2.829 N/A LYS 197.A NZ ARG 263.A O no hydrogen 2.710 N/A ALA 198.A N THR 195.A O no hydrogen 3.356 N/A ASP 199.A N GLU 196.A O no hydrogen 2.965 N/A THR 200.A OG1 GLU 196.A O no hydrogen 3.560 N/A TYR 201.A N LYS 197.A O no hydrogen 3.092 N/A SER 202.A N ALA 198.A O no hydrogen 3.022 N/A SER 202.A OG TRP 181.A O no hydrogen 2.672 N/A SER 202.A OG ALA 198.A O no hydrogen 3.425 N/A PHE 203.A N ASP 199.A O no hydrogen 2.848 N/A ALA 204.A N THR 200.A O no hydrogen 3.342 N/A MET 205.A N TYR 201.A O no hydrogen 3.383 N/A ILE 206.A N SER 202.A O no hydrogen 3.090 N/A LEU 207.A N PHE 203.A O no hydrogen 2.790 N/A TYR 208.A N ALA 204.A O no hydrogen 2.960 N/A THR 209.A N MET 205.A O no hydrogen 3.085 N/A THR 209.A OG1 GLU 214.A O no hydrogen 2.815 N/A ILE 210.A N ILE 206.A O no hydrogen 3.100 N/A LEU 211.A N LEU 207.A O no hydrogen 3.092 N/A THR 212.A N TYR 208.A O no hydrogen 2.946 N/A THR 212.A OG1 TYR 208.A O no hydrogen 3.037 N/A GLY 213.A N THR 209.A O no hydrogen 2.723 N/A GLU 214.A N THR 212.A OG1 no hydrogen 3.099 N/A ASP 218.A N GLY 215.A O no hydrogen 3.179 N/A TYR 220.A N PHE 217.A O no hydrogen 3.038 N/A TYR 220.A OH ARG 237.A O no hydrogen 2.664 N/A PHE 227.A N GLY 223.A O no hydrogen 2.751 N/A ILE 228.A N LYS 224.A O no hydrogen 2.893 N/A ASN 229.A N ILE 225.A O no hydrogen 3.021 N/A MET 230.A N LYS 226.A O no hydrogen 3.023 N/A ILE 231.A N PHE 227.A O no hydrogen 3.145 N/A ARG 232.A N ILE 228.A O no hydrogen 2.982 N/A ARG 232.A NH1 PRO 184.A O no hydrogen 2.775 N/A ARG 232.A NH1 GLU 192.A OE1 no hydrogen 2.805 N/A ARG 232.A NH2 GLU 192.A OE1 no hydrogen 3.095 N/A GLU 233.A N ASN 229.A O no hydrogen 2.667 N/A GLU 234.A N MET 230.A O no hydrogen 3.029 N/A LEU 236.A N MET 230.A O no hydrogen 2.933 N/A ARG 237.A NE TRP 256.A O no hydrogen 2.773 N/A ARG 237.A NH1 TRP 256.A O no hydrogen 2.982 N/A ARG 237.A NH2 ILE 231.A O no hydrogen 3.073 N/A ARG 237.A NH2 LEU 236.A O no hydrogen 2.932 N/A THR 239.A N GLU 219.A OE2 no hydrogen 2.859 N/A THR 239.A OG1 GLU 219.A OE1 no hydrogen 2.570 N/A CYS 244.A N PRO 241.A O no hydrogen 3.271 N/A CYS 244.A SG PRO 245.A O no hydrogen 3.464 N/A ARG 247.A NE GLU 272.A OE1 no hydrogen 3.250 N/A ARG 247.A NH2 GLU 272.A OE1 no hydrogen 3.452 N/A ARG 247.A NH2 GLU 272.A OE2 no hydrogen 2.970 N/A ARG 249.A N PRO 245.A O no hydrogen 2.984 N/A ASN 250.A N PRO 246.A O no hydrogen 3.239 N/A VAL 251.A N ARG 247.A O no hydrogen 3.190 N/A ILE 252.A N LEU 248.A O no hydrogen 3.020 N/A GLU 253.A N ARG 249.A O no hydrogen 2.949 N/A LEU 254.A N ASN 250.A O no hydrogen 2.978 N/A CYS 255.A N VAL 251.A O no hydrogen 2.969 N/A CYS 255.A SG VAL 251.A O no hydrogen 3.158 N/A TRP 256.A N ILE 252.A O no hydrogen 3.052 N/A SER 257.A N LEU 254.A O no hydrogen 3.370 N/A SER 257.A OG GLU 253.A O no hydrogen 3.365 N/A SER 257.A OG LEU 254.A O no hydrogen 2.681 N/A LYS 262.A N ASP 259.A O no hydrogen 3.104 N/A ARG 263.A N PRO 260.A O no hydrogen 3.169 N/A ARG 263.A NE SER 257.A O no hydrogen 2.794 N/A ARG 263.A NH1 GLU 185.A OE2 no hydrogen 2.808 N/A ARG 263.A NH1 LYS 197.A O no hydrogen 2.952 N/A ARG 263.A NH2 GLU 185.A OE1 no hydrogen 2.848 N/A ARG 263.A NH2 GLU 185.A OE2 no hydrogen 3.544 N/A ARG 263.A NH2 SER 257.A O no hydrogen 3.026 N/A HIS 265.A ND1 SER 267.A OG no hydrogen 2.810 N/A SER 267.A N HIS 265.A ND1 no hydrogen 3.183 N/A SER 267.A OG HIS 265.A ND1 no hydrogen 2.810 N/A ILE 269.A N HIS 265.A O no hydrogen 3.277 N/A VAL 270.A N PHE 266.A O no hydrogen 2.892 N/A LYS 271.A N SER 267.A O no hydrogen 3.197 N/A LYS 271.A NZ.B GLU 275.A OE2 no hydrogen 2.766 N/A GLU 272.A N TYR 268.A O no hydrogen 2.923 N/A LEU 273.A N ILE 269.A O no hydrogen 2.946 N/A SER 274.A N VAL 270.A O no hydrogen 2.983 N/A SER 274.A OG VAL 270.A O no hydrogen 3.233 N/A SER 274.A OG LYS 271.A O no hydrogen 2.680 N/A GLU 275.A N GLU 272.A O no hydrogen 3.138 N/A LEU 276.A N LEU 273.A O no hydrogen 3.246 N/A