Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4f49_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 2.A OG GLY 3.A O no hydrogen 3.294 N/A ARG 5.A N GLN 296.A OE1 no hydrogen 3.153 N/A LYS 6.A NZ VAL 128.A O no hydrogen 3.535 N/A LYS 6.A NZ GLU 287.A O no hydrogen 3.134 N/A LYS 6.A NZ GLU 292.A OE1 no hydrogen 2.425 N/A LYS 6.A NZ GLU 292.A OE2 no hydrogen 3.457 N/A GLN 9.A N ASN 113.A OD1 no hydrogen 2.799 N/A GLN 9.A NE2 LEU 152.A O no hydrogen 2.890 N/A SER 11.A OG GLU 15.A OE2 no hydrogen 2.473 N/A VAL 14.A N SER 11.A O no hydrogen 2.767 N/A GLU 15.A N SER 11.A O no hydrogen 3.146 N/A CYS 17.A N VAL 14.A O no hydrogen 3.013 N/A CYS 17.A SG LEU 13.A O no hydrogen 3.721 N/A ILE 18.A N GLU 15.A O no hydrogen 3.244 N/A VAL 19.A N GLY 30.A O no hydrogen 2.874 N/A ARG 20.A N SER 69.A O no hydrogen 2.902 N/A VAL 21.A N LEU 28.A O no hydrogen 2.863 N/A SER 22.A N SER 67.A O no hydrogen 2.862 N/A SER 22.A OG SER 67.A O no hydrogen 3.336 N/A TYR 23.A N ASN 26.A O no hydrogen 3.123 N/A ASN 26.A N TYR 23.A O no hydrogen 3.016 N/A ASN 26.A ND2 VAL 43.A O no hydrogen 2.872 N/A ASN 26.A ND2 ALA 45.A O no hydrogen 2.782 N/A LEU 28.A N VAL 21.A O no hydrogen 3.010 N/A ASN 29.A N CYS 145.A O no hydrogen 2.852 N/A ASN 29.A ND2 CYS 117.A O no hydrogen 2.940 N/A ASN 29.A ND2 GLY 143.A O no hydrogen 3.170 N/A ASN 29.A ND2 CYS 145.A O no hydrogen 2.971 N/A GLY 30.A N VAL 19.A O no hydrogen 2.844 N/A LEU 31.A N ILE 38.A O no hydrogen 2.891 N/A TRP 32.A N CYS 17.A O no hydrogen 2.727 N/A TRP 32.A NE1 GLN 93.A O no hydrogen 3.133 N/A LEU 33.A N GLU 36.A O no hydrogen 2.806 N/A GLY 34.A N THR 98.A OG1 no hydrogen 2.930 N/A GLU 36.A N LEU 33.A O no hydrogen 2.913 N/A VAL 37.A N LEU 89.A O no hydrogen 2.825 N/A ILE 38.A N LEU 31.A O no hydrogen 2.920 N/A CYS 39.A N LEU 87.A O no hydrogen 3.176 N/A CYS 39.A SG PRO 40.A O no hydrogen 3.568 N/A ARG 41.A N VAL 85.A O no hydrogen 2.968 N/A ARG 41.A NE ASP 187.A OD2 no hydrogen 2.637 N/A ARG 41.A NH2 ASP 187.A OD1 no hydrogen 3.097 N/A ARG 41.A NH2 ASP 187.A OD2 no hydrogen 3.544 N/A VAL 43.A N PRO 40.A O no hydrogen 3.322 N/A ILE 44.A N ARG 41.A O no hydrogen 3.095 N/A ALA 45.A N HIS 42.A O no hydrogen 3.096 N/A SER 46.A OG GLU 57.A OE1 no hydrogen 3.462 N/A THR 49.A N ASP 47.A OD1 no hydrogen 2.907 N/A THR 49.A OG1 ASP 47.A OD1 no hydrogen 2.781 N/A THR 49.A OG1 ASP 47.A OD2 no hydrogen 3.544 N/A ILE 52.A N GLN 188.A OE1 no hydrogen 2.860 N/A TYR 54.A OH ASP 187.A O no hydrogen 2.860 N/A ASN 56.A N ASN 53.A OD1 no hydrogen 3.195 N/A GLU 57.A N ASN 53.A O no hydrogen 3.072 N/A MET 58.A N TYR 54.A O no hydrogen 3.156 N/A SER 59.A OG ASN 56.A O no hydrogen 3.377 N/A SER 60.A OG ASN 56.A O no hydrogen 3.296 N/A SER 60.A OG GLU 57.A O no hydrogen 3.249 N/A VAL 61.A N MET 58.A O no hydrogen 3.012 N/A ARG 62.A N TYR 23.A OH no hydrogen 3.357 N/A ASN 65.A N ARG 62.A O no hydrogen 2.792 N/A ASN 65.A ND2 TYR 23.A OH no hydrogen 3.557 N/A PHE 66.A N LEU 63.A O no hydrogen 2.870 N/A SER 67.A N SER 22.A O no hydrogen 2.934 N/A SER 69.A N ARG 20.A O no hydrogen 2.959 N/A LYS 70.A N VAL 73.A O no hydrogen 2.830 N/A LYS 70.A NZ PRO 16.A O no hydrogen 2.794 N/A VAL 73.A N LYS 70.A O no hydrogen 2.614 N/A LEU 75.A N VAL 68.A O no hydrogen 2.949 N/A GLY 76.A N ASN 92.A OD1 no hydrogen 2.938 N/A VAL 78.A N LYS 90.A O no hydrogen 2.744 N/A SER 79.A N LYS 90.A O no hydrogen 3.321 N/A ARG 81.A N VAL 88.A O no hydrogen 2.848 N/A TYR 82.A OH TYR 54.A O no hydrogen 3.052 N/A LYS 83.A N ASN 86.A O no hydrogen 2.795 N/A LYS 83.A NZ PHE 177.A O no hydrogen 3.410 N/A VAL 85.A N GLY 179.A O no hydrogen 2.938 N/A ASN 86.A N LYS 83.A O no hydrogen 3.042 N/A ASN 86.A ND2 ASN 176.A O no hydrogen 2.900 N/A LEU 87.A N CYS 39.A O no hydrogen 2.736 N/A VAL 88.A N ARG 81.A O no hydrogen 2.748 N/A LEU 89.A N VAL 37.A O no hydrogen 2.897 N/A LYS 90.A N SER 79.A O no hydrogen 2.881 N/A LYS 90.A NZ ASP 35.A OD2 no hydrogen 3.121 N/A VAL 91.A N ASP 35.A O no hydrogen 2.860 N/A ASN 92.A N GLY 76.A O no hydrogen 2.827 N/A ASN 95.A N GLY 34.A O no hydrogen 2.913 N/A ASN 95.A ND2 PRO 16.A O no hydrogen 3.191 N/A ASN 95.A ND2 TRP 32.A O no hydrogen 2.889 N/A ASN 97.A N ASN 95.A OD1 no hydrogen 2.832 N/A THR 98.A N ASN 95.A O no hydrogen 3.034 N/A THR 98.A OG1 ASN 95.A O no hydrogen 2.762 N/A HIS 101.A ND1 PRO 99.A O no hydrogen 2.842 N/A LYS 102.A N LEU 157.A O no hydrogen 2.814 N/A LYS 104.A NZ GLU 153.A OE1 no hydrogen 2.446 N/A ILE 106.A N TYR 182.A OH no hydrogen 3.068 N/A LYS 107.A N GLU 110.A OE1 no hydrogen 2.904 N/A GLY 109.A N MET 130.A O no hydrogen 2.815 N/A GLU 110.A N LYS 107.A O no hydrogen 2.956 N/A SER 111.A OG GLU 287.A O no hydrogen 3.569 N/A SER 111.A OG GLU 292.A OE1 no hydrogen 3.454 N/A SER 111.A OG GLU 292.A OE2 no hydrogen 2.868 N/A PHE 112.A N VAL 128.A O no hydrogen 3.049 N/A ASN 113.A N TYR 150.A O no hydrogen 3.024 N/A ASN 113.A ND2 GLN 9.A OE1 no hydrogen 2.840 N/A ASN 113.A ND2 TYR 150.A O no hydrogen 2.914 N/A ILE 114.A N TYR 126.A O no hydrogen 2.957 N/A LEU 115.A N VAL 148.A O no hydrogen 2.930 N/A ALA 116.A N SER 124.A O no hydrogen 2.636 N/A CYS 117.A N SER 147.A OG no hydrogen 2.984 N/A CYS 117.A SG LEU 115.A O no hydrogen 3.574 N/A TYR 118.A N CYS 121.A O no hydrogen 3.023 N/A GLU 119.A N GLY 143.A O no hydrogen 3.062 N/A GLY 120.A N ASN 29.A OD1 no hydrogen 2.841 N/A CYS 121.A N TYR 118.A O no hydrogen 2.955 N/A CYS 121.A SG TYR 118.A O no hydrogen 3.662 N/A GLY 123.A N ALA 116.A O no hydrogen 2.818 N/A SER 124.A N ALA 116.A O no hydrogen 3.124 N/A TYR 126.A N ILE 114.A O no hydrogen 3.141 N/A VAL 128.A N PHE 112.A O no hydrogen 2.807 N/A ASN 129.A ND2 GLY 109.A O no hydrogen 2.860 N/A ASN 129.A ND2 SER 111.A OG no hydrogen 3.029 N/A MET 130.A N GLU 110.A O no hydrogen 2.947 N/A ARG 131.A N THR 135.A O no hydrogen 2.836 N/A ARG 131.A NE THR 135.A OG1 no hydrogen 3.324 N/A ARG 131.A NE GLU 194.A OE1 no hydrogen 2.871 N/A ARG 131.A NH1 GLU 194.A OE1 no hydrogen 3.307 N/A ARG 131.A NH1 GLU 194.A OE2 no hydrogen 3.473 N/A GLN 133.A NE2 SER 132.A OG no hydrogen 3.175 N/A GLY 134.A N ARG 131.A O no hydrogen 3.023 N/A THR 135.A OG1 GLU 194.A OE1 no hydrogen 2.586 N/A ILE 136.A N HIS 172.A O no hydrogen 2.964 N/A LYS 137.A NZ SER 171.A OG no hydrogen 3.075 N/A THR 144.A N ILE 141.A O no hydrogen 3.405 N/A THR 144.A OG1 ILE 141.A O no hydrogen 3.089 N/A CYS 145.A SG HIS 42.A NE2 no hydrogen 3.632 N/A CYS 145.A SG HIS 164.A O no hydrogen 2.994 N/A GLY 146.A N HIS 163.A O no hydrogen 2.809 N/A SER 147.A N THR 144.A O no hydrogen 3.013 N/A SER 147.A OG THR 144.A O no hydrogen 2.555 N/A VAL 148.A N LEU 115.A O no hydrogen 3.440 N/A GLY 149.A N TYR 161.A O no hydrogen 2.857 N/A TYR 150.A N ASN 113.A O no hydrogen 2.914 N/A TYR 150.A OH GLN 9.A O no hydrogen 2.753 N/A VAL 151.A N TYR 158.A O no hydrogen 2.865 N/A LEU 152.A N GLN 9.A OE1 no hydrogen 2.864 N/A GLU 153.A N ILE 156.A O no hydrogen 3.002 N/A ILE 156.A N GLU 153.A O no hydrogen 3.116 N/A TYR 158.A N VAL 151.A O no hydrogen 2.815 N/A PHE 159.A N LYS 102.A O no hydrogen 2.882 N/A VAL 160.A N GLY 149.A O no hydrogen 2.846 N/A TYR 161.A N GLY 149.A O no hydrogen 3.318 N/A TYR 161.A OH HIS 163.A ND1 no hydrogen 2.971 N/A MET 162.A N SER 175.A O no hydrogen 2.772 N/A HIS 163.A N SER 147.A O no hydrogen 3.032 N/A HIS 163.A ND1 TYR 161.A OH no hydrogen 2.971 N/A HIS 164.A N VAL 173.A O no hydrogen 3.057 N/A HIS 164.A NE2 ASN 86.A OD1 no hydrogen 3.307 N/A LEU 165.A N VAL 173.A O no hydrogen 3.056 N/A LEU 167.A N SER 171.A O no hydrogen 2.714 N/A ASN 169.A ND2 GLU 194.A OE2 no hydrogen 2.524 N/A GLY 170.A N LEU 167.A O no hydrogen 2.910 N/A SER 171.A N ASN 169.A OD1 no hydrogen 3.058 N/A SER 171.A OG ASN 169.A OD1 no hydrogen 3.154 N/A SER 171.A OG GLU 194.A OE2 no hydrogen 2.612 N/A HIS 172.A N ILE 136.A O no hydrogen 2.723 N/A HIS 172.A NE2 GLU 166.A OE1 no hydrogen 2.760 N/A VAL 173.A N LEU 165.A O no hydrogen 2.902 N/A SER 175.A N MET 162.A O no hydrogen 2.812 N/A SER 175.A OG ASN 86.A OD1 no hydrogen 2.741 N/A SER 175.A OG ASN 176.A O no hydrogen 2.889 N/A ASN 176.A N GLU 180.A O no hydrogen 3.061 N/A ASN 176.A ND2 SER 105.A OG no hydrogen 2.879 N/A ASN 176.A ND2 GLU 180.A OE1 no hydrogen 3.198 N/A GLU 178.A N ASN 176.A OD1 no hydrogen 3.008 N/A GLY 179.A N ASN 176.A O no hydrogen 3.220 N/A GLU 180.A N ASN 176.A OD1 no hydrogen 3.075 N/A TYR 182.A N GLY 174.A O no hydrogen 2.871 N/A TYR 182.A OH VAL 160.A O no hydrogen 2.722 N/A GLY 184.A N MET 181.A O no hydrogen 2.796 N/A TYR 185.A OH GLN 133.A O no hydrogen 3.255 N/A TYR 185.A OH GLU 194.A O no hydrogen 2.701 N/A GLU 186.A N GLN 192.A OE1 no hydrogen 3.048 N/A GLN 188.A NE2 ILE 52.A O no hydrogen 3.155 N/A GLN 192.A NE2 GLU 186.A O no hydrogen 3.254 N/A VAL 198.A N SER 132.A OG no hydrogen 3.048 N/A MET 199.A N SER 238.A O no hydrogen 2.772 N/A SER 200.A N ASP 286.A OD2 no hydrogen 3.039 N/A SER 201.A N THR 240.A OG1 no hydrogen 2.731 N/A SER 201.A OG TYR 230.A OH no hydrogen 2.662 N/A SER 201.A OG THR 240.A O no hydrogen 2.617 N/A ASN 203.A N SER 200.A OG no hydrogen 3.128 N/A ASN 203.A ND2 GLY 109.A O no hydrogen 3.048 N/A ASN 203.A ND2 ASP 286.A O no hydrogen 2.946 N/A VAL 204.A N SER 200.A O no hydrogen 2.954 N/A VAL 205.A N SER 201.A O no hydrogen 2.842 N/A ALA 206.A N ASP 202.A O no hydrogen 2.917 N/A PHE 207.A N ASN 203.A O no hydrogen 2.951 N/A LEU 208.A N VAL 204.A O no hydrogen 2.910 N/A TYR 209.A N VAL 205.A O no hydrogen 2.921 N/A TYR 209.A OH GLN 257.A O no hydrogen 2.687 N/A ALA 210.A N ALA 206.A O no hydrogen 3.046 N/A ALA 211.A N PHE 207.A O no hydrogen 3.051 N/A LEU 212.A N LEU 208.A O no hydrogen 3.031 N/A ILE 213.A N TYR 209.A O no hydrogen 2.856 N/A ASN 214.A N ALA 210.A O no hydrogen 3.121 N/A GLY 215.A N LEU 212.A O no hydrogen 2.882 N/A GLU 216.A N ALA 211.A O no hydrogen 3.009 N/A TRP 218.A NE1 THR 277.A O no hydrogen 2.680 N/A VAL 220.A N ARG 217.A O no hydrogen 3.032 N/A THR 221.A OG1 THR 223.A OG1 no hydrogen 2.975 N/A THR 223.A OG1 THR 221.A OG1 no hydrogen 2.975 N/A THR 223.A OG1 ASP 264.A OD2 no hydrogen 2.716 N/A MET 225.A N GLU 260.A O no hydrogen 3.046 N/A SER 229.A N SER 226.A OG no hydrogen 3.165 N/A TYR 230.A N SER 226.A O no hydrogen 2.811 N/A TYR 230.A OH SER 201.A OG no hydrogen 2.662 N/A ASN 231.A N LEU 227.A O no hydrogen 2.885 N/A ASN 231.A ND2 LEU 242.A O no hydrogen 3.031 N/A THR 232.A N GLU 228.A O no hydrogen 3.108 N/A THR 232.A OG1 GLU 228.A O no hydrogen 3.471 N/A TRP 233.A N SER 229.A O no hydrogen 3.031 N/A ALA 234.A N TYR 230.A O no hydrogen 2.852 N/A LYS 235.A N ASN 231.A O no hydrogen 3.166 N/A THR 236.A N TRP 233.A O no hydrogen 3.130 N/A THR 236.A OG1 TRP 233.A O no hydrogen 3.174 N/A THR 236.A OG1 ASN 237.A OD1 no hydrogen 3.110 N/A ASN 237.A N ALA 234.A O no hydrogen 3.064 N/A PHE 239.A N ALA 234.A O no hydrogen 3.158 N/A THR 240.A N MET 199.A O no hydrogen 2.911 N/A THR 240.A OG1 MET 199.A O no hydrogen 3.570 N/A LEU 242.A N ASN 231.A OD1 no hydrogen 2.751 N/A SER 244.A OG ASP 246.A OD2 no hydrogen 2.505 N/A ASP 246.A N SER 244.A OG no hydrogen 2.920 N/A PHE 248.A N THR 245.A O no hydrogen 3.171 N/A SER 249.A N ASP 246.A O no hydrogen 3.342 N/A SER 249.A OG ASP 246.A O no hydrogen 3.234 N/A ALA 252.A N PHE 248.A O no hydrogen 2.802 N/A ALA 253.A N SER 249.A O no hydrogen 2.827 N/A LYS 254.A N MET 250.A O no hydrogen 2.900 N/A THR 255.A N LEU 251.A O no hydrogen 2.967 N/A THR 255.A OG1 LEU 251.A O no hydrogen 2.691 N/A GLN 257.A N THR 255.A OG1 no hydrogen 3.343 N/A GLU 260.A N GLU 260.A OE2 no hydrogen 2.881 N/A LYS 261.A N SER 258.A O no hydrogen 2.878 N/A LYS 261.A N SER 258.A OG no hydrogen 3.307 N/A LEU 262.A N SER 258.A O no hydrogen 3.406 N/A LEU 263.A N VAL 259.A O no hydrogen 2.866 N/A ASP 264.A N GLU 260.A O no hydrogen 3.419 N/A SER 265.A N LYS 261.A O no hydrogen 3.173 N/A SER 265.A OG PHE 219.A O no hydrogen 2.750 N/A SER 265.A OG LYS 261.A O no hydrogen 3.356 N/A ILE 266.A N LEU 262.A O no hydrogen 3.049 N/A VAL 267.A N LEU 263.A O no hydrogen 3.280 N/A ARG 268.A N ASP 264.A O no hydrogen 3.013 N/A ARG 268.A NE ASP 264.A OD2 no hydrogen 2.760 N/A ARG 268.A NH1 PHE 219.A O no hydrogen 3.424 N/A ARG 268.A NH2 PHE 219.A O no hydrogen 2.842 N/A ARG 268.A NH2 ASP 264.A OD2 no hydrogen 3.230 N/A LEU 269.A N SER 265.A O no hydrogen 2.760 N/A ASN 270.A N ILE 266.A O no hydrogen 2.689 N/A LYS 271.A N ARG 268.A O no hydrogen 3.211 N/A GLY 272.A N LEU 269.A O no hydrogen 2.835 N/A ARG 276.A N PHE 273.A O no hydrogen 3.201 N/A ILE 278.A N TYR 281.A O no hydrogen 2.971 N/A LEU 279.A N GLU 216.A OE1 no hydrogen 2.704 N/A TYR 281.A N ILE 278.A O no hydrogen 2.906 N/A THR 289.A N GLU 292.A OE2 no hydrogen 2.907 N/A THR 289.A OG1 GLU 292.A OE2 no hydrogen 3.295 N/A GLU 292.A N THR 289.A OG1 no hydrogen 2.984 N/A VAL 293.A N THR 289.A O no hydrogen 3.071 N/A ILE 294.A N PRO 290.A O no hydrogen 2.957 N/A ARG 295.A N THR 291.A O no hydrogen 2.936 N/A GLN 296.A N GLU 292.A O no hydrogen 3.091 N/A GLN 296.A NE2 ARG 5.A O no hydrogen 2.759 N/A MET 297.A N VAL 293.A O no hydrogen 2.910 N/A TYR 298.A N ILE 294.A O no hydrogen 2.865 N/A GLY 299.A N ILE 294.A O no hydrogen 3.297 N/A GLY 299.A N ARG 295.A O no hydrogen 2.857 N/A