Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4fh3_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): HIS 2.A NE2 HIS 234.A ND1 no hydrogen 2.925 N/A LYS 3.A N SER 1.A OG no hydrogen 3.236 N/A THR 6.A N HIS 2.A O no hydrogen 2.829 N/A THR 6.A OG1 HIS 2.A O no hydrogen 2.867 N/A THR 6.A OG1 SER 228.A OG no hydrogen 3.134 N/A LYS 7.A N LYS 3.A O no hydrogen 3.120 N/A PHE 8.A N GLU 4.A O no hydrogen 2.996 N/A CYS 9.A N PHE 5.A O no hydrogen 2.802 N/A CYS 9.A SG PHE 5.A O no hydrogen 3.259 N/A TYR 10.A N THR 6.A O no hydrogen 3.025 N/A GLU 11.A N LYS 7.A O no hydrogen 3.168 N/A VAL 12.A N PHE 8.A O no hydrogen 3.043 N/A TYR 13.A N CYS 9.A O no hydrogen 2.875 N/A ASN 14.A N TYR 10.A O no hydrogen 3.033 N/A GLU 15.A N GLU 11.A O no hydrogen 3.354 N/A GLU 15.A N VAL 12.A O no hydrogen 2.971 N/A ILE 16.A N VAL 12.A O no hydrogen 2.932 N/A ILE 16.A N TYR 13.A O no hydrogen 3.332 N/A LYS 17.A N TYR 13.A O no hydrogen 3.043 N/A LYS 17.A NZ ASN 14.A OD1 no hydrogen 3.115 N/A ILE 18.A N ALA 57.A O no hydrogen 3.097 N/A GLU 22.A N SER 19.A OG no hydrogen 3.038 N/A PHE 23.A N SER 19.A O no hydrogen 3.041 N/A LYS 24.A N ASP 20.A O no hydrogen 2.999 N/A GLU 25.A N LYS 21.A O no hydrogen 3.135 N/A LYS 26.A N GLU 22.A O no hydrogen 2.915 N/A ARG 27.A N PHE 23.A O no hydrogen 2.966 N/A ALA 28.A N LYS 24.A O no hydrogen 2.974 N/A ALA 29.A N GLU 25.A O no hydrogen 2.967 N/A LEU 30.A N LYS 26.A O no hydrogen 3.026 N/A ASP 31.A N ARG 27.A O no hydrogen 3.060 N/A THR 32.A N ALA 28.A O no hydrogen 3.108 N/A THR 32.A OG1 ALA 29.A O no hydrogen 2.970 N/A LEU 33.A N ALA 29.A O no hydrogen 2.916 N/A ARG 34.A N LEU 30.A O no hydrogen 2.886 N/A ARG 34.A NE LEU 46.A O no hydrogen 2.840 N/A ARG 34.A NH2 LEU 46.A O no hydrogen 2.964 N/A LEU 35.A N ASP 31.A O no hydrogen 3.177 N/A CYS 36.A N THR 32.A O no hydrogen 3.142 N/A CYS 36.A SG THR 32.A O no hydrogen 3.465 N/A LEU 37.A N LEU 33.A O no hydrogen 3.079 N/A LYS 38.A N ARG 34.A O no hydrogen 2.854 N/A LYS 38.A NZ PRO 42.A O no hydrogen 2.782 N/A ARG 39.A N LEU 35.A O no hydrogen 3.262 N/A ARG 39.A NE GLU 85.A OE2 no hydrogen 3.070 N/A ARG 39.A NH2 GLU 85.A OE2 no hydrogen 3.152 N/A ILE 40.A N LEU 37.A O no hydrogen 2.854 N/A SER 41.A N LEU 37.A O no hydrogen 2.779 N/A ALA 44.A N SER 41.A O no hydrogen 3.248 N/A GLU 45.A N LEU 68.A O no hydrogen 2.895 N/A VAL 47.A N CYS 66.A O no hydrogen 2.885 N/A PHE 49.A N ASP 64.A O no hydrogen 2.932 N/A GLY 50.A N THR 133.A OG1 no hydrogen 2.871 N/A SER 51.A OG.B SER 61.A OG no hydrogen 3.288 N/A GLU 53.A N GLY 50.A O no hydrogen 3.047 N/A SER 54.A N GLY 50.A O no hydrogen 2.997 N/A SER 54.A OG GLY 50.A O no hydrogen 3.401 N/A SER 54.A OG SER 51.A O no hydrogen 3.306 N/A LEU 56.A N SER 51.A O no hydrogen 2.883 N/A LYS 59.A N ILE 16.A O no hydrogen 2.955 N/A LYS 59.A NZ GLU 15.A O no hydrogen 2.793 N/A ASN 60.A N GLU 22.A OE2 no hydrogen 2.749 N/A SER 61.A N GLU 22.A OE1 no hydrogen 3.012 N/A SER 61.A OG SER 51.A OG.B no hydrogen 3.288 N/A SER 61.A OG ASP 62.A O no hydrogen 3.027 N/A MET 63.A N GLN 119.A O no hydrogen 3.017 N/A LEU 65.A N ASP 121.A O no hydrogen 2.798 N/A CYS 66.A N VAL 47.A O no hydrogen 2.735 N/A VAL 67.A N GLY 123.A O no hydrogen 2.773 N/A LEU 68.A N GLU 45.A O no hydrogen 2.703 N/A MET 69.A N ASN 125.A OD1 no hydrogen 3.111 N/A ARG 72.A N ASP 70.A OD2 no hydrogen 3.204 N/A VAL 73.A N ASP 70.A O no hydrogen 2.996 N/A THR 77.A N GLN 74.A O no hydrogen 3.340 N/A ALA 79.A N SER 75.A O no hydrogen 2.908 N/A LEU 80.A N ASP 76.A O no hydrogen 3.009 N/A GLN 81.A N THR 77.A O no hydrogen 3.081 N/A PHE 82.A N ILE 78.A O no hydrogen 2.695 N/A TYR 83.A N ALA 79.A O no hydrogen 2.797 N/A TYR 83.A OH GLY 93.A O no hydrogen 2.653 N/A GLU 84.A N LEU 80.A O no hydrogen 2.870 N/A GLU 85.A N GLN 81.A O no hydrogen 3.098 N/A LEU 86.A N PHE 82.A O no hydrogen 3.016 N/A ILE 87.A N TYR 83.A O no hydrogen 3.067 N/A ALA 88.A N GLU 84.A O no hydrogen 3.142 N/A GLU 89.A N GLU 85.A O no hydrogen 3.034 N/A GLU 89.A N LEU 86.A O no hydrogen 3.201 N/A GLY 90.A N ILE 87.A O no hydrogen 2.891 N/A PHE 91.A N LEU 86.A O no hydrogen 2.999 N/A GLU 92.A N SER 108.A O no hydrogen 3.002 N/A LYS 94.A N LYS 105.A O no hydrogen 2.890 N/A LEU 96.A N ILE 103.A O no hydrogen 2.956 N/A GLN 97.A NE2 ALA 99.A O no hydrogen 2.759 N/A ARG 98.A N ILE 101.A O no hydrogen 2.999 N/A ILE 101.A N ARG 98.A O no hydrogen 2.941 N/A ILE 103.A N LEU 96.A O no hydrogen 2.717 N/A ILE 104.A N ILE 122.A O no hydrogen 2.891 N/A LYS 105.A N LYS 94.A O no hydrogen 2.900 N/A LYS 105.A NZ ASP 121.A OD1 no hydrogen 3.335 N/A LEU 106.A N CYS 120.A O no hydrogen 2.751 N/A THR 107.A N GLU 92.A O no hydrogen 2.877 N/A THR 107.A OG1 GLU 92.A O no hydrogen 3.553 N/A SER 108.A OG ALA 116.A O no hydrogen 2.869 N/A ASP 109.A N GLY 115.A O no hydrogen 3.109 N/A THR 110.A N GLY 90.A O no hydrogen 3.062 N/A THR 110.A OG1 GLY 90.A O no hydrogen 2.833 N/A LYS 111.A N ASP 109.A OD1 no hydrogen 3.279 N/A LYS 111.A NZ GLU 89.A OE2 no hydrogen 3.219 N/A ASN 112.A N ASP 109.A OD1 no hydrogen 2.998 N/A ASN 112.A ND2 GLU 89.A O no hydrogen 2.896 N/A ASN 112.A ND2 ASP 109.A OD1 no hydrogen 3.043 N/A PHE 114.A N ASP 109.A OD2 no hydrogen 2.926 N/A CYS 120.A N LEU 106.A O no hydrogen 2.900 N/A ASP 121.A N MET 63.A O no hydrogen 2.963 N/A ILE 122.A N ILE 104.A O no hydrogen 2.677 N/A GLY 123.A N LEU 65.A O no hydrogen 2.870 N/A ASN 125.A N VAL 67.A O no hydrogen 2.760 N/A ASN 125.A ND2 MET 69.A O no hydrogen 3.386 N/A ARG 127.A NH2 ASN 125.A OD1 no hydrogen 2.999 N/A ALA 129.A N ASN 126.A OD1 no hydrogen 3.248 N/A HIS 131.A N ARG 127.A O no hydrogen 3.139 N/A ASN 132.A N LEU 128.A O no hydrogen 2.774 N/A THR 133.A N ALA 129.A O no hydrogen 3.083 N/A THR 133.A OG1 ALA 129.A O no hydrogen 2.858 N/A LEU 134.A N ILE 130.A O no hydrogen 2.959 N/A LEU 135.A N HIS 131.A O no hydrogen 3.088 N/A LEU 136.A N ASN 132.A O no hydrogen 3.180 N/A SER 137.A N THR 133.A O no hydrogen 2.761 N/A SER 137.A OG THR 133.A O no hydrogen 2.818 N/A SER 138.A N LEU 134.A O no hydrogen 2.947 N/A SER 138.A OG LEU 134.A O no hydrogen 3.141 N/A TYR 139.A N LEU 135.A O no hydrogen 3.063 N/A TYR 139.A OH PRO 193.A O no hydrogen 2.713 N/A THR 140.A N LEU 136.A O no hydrogen 2.965 N/A THR 140.A OG1 LEU 136.A O no hydrogen 2.897 N/A LYS 141.A N SER 137.A O no hydrogen 3.101 N/A LEU 142.A N SER 138.A O no hydrogen 3.044 N/A ASP 143.A N TYR 139.A O no hydrogen 3.324 N/A ARG 145.A N ASP 143.A OD2 no hydrogen 3.000 N/A ARG 145.A NE ASP 143.A OD2 no hydrogen 2.790 N/A ARG 145.A NH1 ASN 225.A O no hydrogen 2.989 N/A ARG 145.A NH1 SER 227.A O no hydrogen 2.947 N/A ARG 145.A NH2 ASP 143.A OD1 no hydrogen 2.810 N/A ARG 145.A NH2 ASP 143.A OD2 no hydrogen 3.520 N/A ARG 145.A NH2 ASN 225.A O no hydrogen 3.113 N/A LEU 146.A N ASP 143.A O no hydrogen 3.288 N/A LYS 147.A NZ TYR 13.A OH no hydrogen 3.014 N/A MET 149.A N ARG 145.A O no hydrogen 3.195 N/A VAL 150.A N LEU 146.A O no hydrogen 2.841 N/A LEU 151.A N LYS 147.A O no hydrogen 2.994 N/A LEU 152.A N PRO 148.A O no hydrogen 2.955 N/A VAL 153.A N MET 149.A O no hydrogen 2.982 N/A LYS 154.A N VAL 150.A O no hydrogen 2.883 N/A LYS 154.A NZ LEU 56.A O no hydrogen 2.984 N/A HIS 155.A N LEU 151.A O no hydrogen 2.887 N/A TRP 156.A N LEU 152.A O no hydrogen 2.829 N/A ALA 157.A N VAL 153.A O no hydrogen 2.830 N/A LYS 158.A N LYS 154.A O no hydrogen 2.985 N/A ARG 159.A N HIS 155.A O no hydrogen 2.946 N/A ARG 159.A NH1 PHE 320.A O no hydrogen 2.663 N/A LYS 160.A N TRP 156.A O no hydrogen 2.875 N/A LYS 160.A NZ SER 318.A O no hydrogen 2.882 N/A LYS 160.A NZ GLU 321.A O no hydrogen 2.803 N/A GLN 161.A N LYS 158.A O no hydrogen 3.130 N/A ILE 162.A N ALA 157.A O no hydrogen 2.954 N/A ASN 163.A ND2 LEU 170.A O no hydrogen 2.955 N/A ASN 163.A ND2 SER 172.A OG no hydrogen 3.221 N/A SER 164.A N THR 169.A OG1 no hydrogen 2.839 N/A PHE 167.A N SER 164.A O no hydrogen 2.887 N/A THR 169.A N SER 164.A O no hydrogen 3.068 N/A THR 169.A OG1 SER 164.A O no hydrogen 3.240 N/A LEU 170.A N ILE 162.A O no hydrogen 3.342 N/A SER 172.A OG ASN 163.A OD1 no hydrogen 3.460 N/A TYR 173.A OH ASP 276.A OD1 no hydrogen 2.454 N/A GLY 174.A N SER 171.A OG no hydrogen 2.967 N/A TYR 175.A N SER 171.A O no hydrogen 3.167 N/A TYR 175.A OH ILE 162.A O no hydrogen 2.649 N/A VAL 176.A N SER 172.A O no hydrogen 2.923 N/A LEU 177.A N TYR 173.A O no hydrogen 2.997 N/A MET 178.A N GLY 174.A O no hydrogen 2.946 N/A VAL 179.A N TYR 175.A O no hydrogen 2.984 N/A LEU 180.A N VAL 176.A O no hydrogen 2.948 N/A TYR 181.A N LEU 177.A O no hydrogen 2.839 N/A TYR 181.A OH GLY 258.A O no hydrogen 2.686 N/A TYR 182.A N MET 178.A O no hydrogen 3.137 N/A LEU 183.A N VAL 179.A O no hydrogen 2.947 N/A ILE 184.A N LEU 180.A O no hydrogen 2.864 N/A HIS 185.A N TYR 181.A O no hydrogen 2.848 N/A VAL 186.A N TYR 182.A O no hydrogen 3.101 N/A ILE 187.A N TYR 182.A O no hydrogen 3.020 N/A VAL 191.A N LEU 183.A O no hydrogen 2.917 N/A PHE 192.A N LEU 183.A O no hydrogen 3.323 N/A ASN 194.A ND2 HIS 185.A NE2 no hydrogen 2.997 N/A ASN 194.A ND2 PHE 253.A O no hydrogen 2.760 N/A LEU 195.A N TYR 139.A OH no hydrogen 2.991 N/A LEU 196.A N ASN 194.A OD1 no hydrogen 2.931 N/A LEU 197.A N ASN 194.A O no hydrogen 3.297 N/A LEU 197.A N ASN 194.A OD1 no hydrogen 3.140 N/A SER 198.A OG ASP 214.A OD1 no hydrogen 3.467 N/A LEU 200.A N SER 198.A OG no hydrogen 3.072 N/A LYS 201.A N SER 198.A O no hydrogen 3.108 N/A LYS 201.A NZ ASP 210.A OD1 no hydrogen 2.570 N/A LYS 204.A N ASP 210.A OD2 no hydrogen 3.020 N/A VAL 206.A N PHE 209.A O no hydrogen 2.881 N/A PHE 209.A N VAL 206.A O no hydrogen 3.029 N/A VAL 211.A N LYS 204.A O no hydrogen 2.803 N/A GLY 212.A N ASP 210.A OD2 no hydrogen 2.887 N/A ASP 214.A N LEU 195.A O no hydrogen 2.841 N/A LYS 216.A N ASP 214.A OD2 no hydrogen 3.208 N/A LEU 217.A N ASP 215.A O no hydrogen 2.915 N/A GLU 218.A N GLU 218.A OE2 no hydrogen 2.796 N/A ASP 219.A N LYS 216.A O no hydrogen 3.295 N/A ILE 220.A N LEU 217.A O no hydrogen 2.998 N/A SER 223.A OG PRO 190.A O no hydrogen 3.182 N/A SER 223.A OG ASN 225.A O no hydrogen 3.513 N/A ASN 225.A N SER 223.A OG no hydrogen 2.835 N/A ASN 225.A ND2 PRO 189.A O no hydrogen 2.733 N/A SER 227.A N ASN 225.A OD1 no hydrogen 3.016 N/A SER 227.A OG ASN 225.A OD1 no hydrogen 2.617 N/A SER 228.A OG THR 6.A OG1 no hydrogen 3.134 N/A SER 228.A OG SER 231.A OG.A no hydrogen 3.056 N/A GLY 230.A N THR 6.A OG1 no hydrogen 2.978 N/A SER 231.A N SER 228.A OG no hydrogen 3.167 N/A SER 231.A OG.A HIS 2.A ND1 no hydrogen 2.794 N/A SER 231.A OG.A SER 228.A OG no hydrogen 3.056 N/A LEU 232.A N SER 228.A O no hydrogen 2.968 N/A LEU 233.A N LEU 229.A O no hydrogen 3.020 N/A HIS 234.A N GLY 230.A O no hydrogen 3.067 N/A HIS 234.A ND1 HIS 2.A NE2 no hydrogen 2.925 N/A GLY 235.A N SER 231.A O no hydrogen 2.992 N/A PHE 236.A N LEU 232.A O no hydrogen 2.924 N/A PHE 237.A N LEU 233.A O no hydrogen 2.973 N/A ARG 238.A N HIS 234.A O no hydrogen 3.019 N/A PHE 239.A N GLY 235.A O no hydrogen 2.850 N/A TYR 240.A N PHE 236.A O no hydrogen 3.308 N/A TYR 240.A OH MET 178.A O no hydrogen 2.641 N/A ALA 241.A N PHE 237.A O no hydrogen 2.863 N/A TYR 242.A N ARG 238.A O no hydrogen 2.871 N/A LYS 243.A N PHE 239.A O no hydrogen 2.924 N/A PHE 244.A N PHE 239.A O no hydrogen 2.750 N/A GLU 248.A N GLU 245.A O no hydrogen 3.116 N/A LYS 249.A N GLU 245.A O no hydrogen 2.986 N/A LYS 249.A NZ GLU 245.A OE1 no hydrogen 3.470 N/A VAL 250.A N LEU 260.A O no hydrogen 2.757 N/A VAL 251.A N ALA 273.A O no hydrogen 2.908 N/A THR 252.A OG1 GLU 275.A OE1 no hydrogen 2.702 N/A ARG 254.A N THR 252.A OG1 no hydrogen 3.187 N/A ARG 254.A NE PRO 277.A O no hydrogen 2.933 N/A ARG 254.A NH2 ASP 210.A O no hydrogen 3.085 N/A ARG 254.A NH2 PRO 277.A O no hydrogen 2.762 N/A ARG 255.A NH1 GLU 264.A OE2 no hydrogen 3.254 N/A ARG 255.A NH2 GLU 264.A OE2 no hydrogen 2.750 N/A GLY 258.A N ARG 255.A O no hydrogen 3.057 N/A TYR 259.A N ASP 257.A OD2 no hydrogen 3.128 N/A THR 261.A N GLU 264.A OE1 no hydrogen 3.165 N/A THR 261.A OG1 GLU 264.A OE1 no hydrogen 3.230 N/A LYS 262.A N GLU 248.A O no hydrogen 2.797 N/A LYS 262.A NZ PRO 246.A O no hydrogen 2.828 N/A LYS 262.A NZ ARG 247.A O no hydrogen 3.428 N/A LYS 262.A NZ TYR 270.A O no hydrogen 2.653 N/A LYS 262.A NZ ILE 271.A O no hydrogen 3.125 N/A GLN 263.A N GLN 263.A OE1 no hydrogen 2.840 N/A GLU 264.A N THR 261.A OG1 no hydrogen 3.202 N/A LYS 265.A NZ GLU 275.A OE2 no hydrogen 2.757 N/A LYS 265.A NZ ILE 280.A O no hydrogen 2.755 N/A GLY 266.A N GLN 263.A O no hydrogen 2.992 N/A TRP 267.A N LYS 262.A O no hydrogen 2.713 N/A ILE 274.A N ASN 283.A OD1 no hydrogen 2.806 N/A GLU 275.A N VAL 251.A O no hydrogen 2.877 N/A ASP 276.A N HIS 282.A O no hydrogen 3.115 N/A HIS 282.A N GLU 279.A O no hydrogen 2.941 N/A ASN 283.A ND2 ARG 269.A O no hydrogen 2.997 N/A ASN 283.A ND2 LEU 272.A O no hydrogen 3.056 N/A VAL 284.A N ILE 274.A O no hydrogen 2.797 N/A GLY 285.A N ASN 283.A OD1 no hydrogen 2.967 N/A ARG 286.A N ASN 283.A O no hydrogen 3.100 N/A THR 287.A OG1 THR 169.A O no hydrogen 2.721 N/A VAL 288.A N GLY 285.A O no hydrogen 2.975 N/A SER 289.A N GLY 168.A O no hydrogen 2.917 N/A SER 289.A OG GLY 168.A O no hydrogen 3.434 N/A SER 289.A OG SER 291.A OG no hydrogen 3.320 N/A SER 291.A OG SER 289.A OG no hydrogen 3.320 N/A GLY 292.A N SER 289.A OG no hydrogen 3.031 N/A LEU 293.A N SER 289.A O no hydrogen 2.837 N/A TYR 294.A N SER 290.A O no hydrogen 3.031 N/A ARG 295.A N SER 291.A O no hydrogen 3.109 N/A ARG 295.A NH1 GLN 161.A O no hydrogen 2.964 N/A ILE 296.A N GLY 292.A O no hydrogen 2.976 N/A ARG 297.A N LEU 293.A O no hydrogen 2.866 N/A GLY 298.A N TYR 294.A O no hydrogen 2.859 N/A GLU 299.A N ARG 295.A O no hydrogen 2.792 N/A PHE 300.A N ILE 296.A O no hydrogen 2.926 N/A MET 301.A N ARG 297.A O no hydrogen 2.876 N/A ALA 302.A N GLY 298.A O no hydrogen 2.870 N/A ALA 303.A N GLU 299.A O no hydrogen 2.853 N/A SER 304.A N PHE 300.A O no hydrogen 3.014 N/A SER 304.A OG.A PHE 300.A O no hydrogen 3.032 N/A ARG 305.A N MET 301.A O no hydrogen 2.921 N/A LEU 306.A N ALA 302.A O no hydrogen 2.991 N/A LEU 307.A N ALA 303.A O no hydrogen 3.151 N/A ASN 308.A N ARG 305.A O no hydrogen 3.192 N/A SER 309.A N LEU 306.A O no hydrogen 3.144 N/A SER 311.A N SER 309.A OG no hydrogen 3.144 N/A TYR 316.A N ILE 314.A O no hydrogen 2.892 N/A SER 318.A N PRO 315.A O no hydrogen 2.964 N/A SER 318.A OG PRO 315.A O no hydrogen 2.841 N/A LEU 319.A N TYR 316.A O no hydrogen 2.979 N/A PHE 320.A N ASP 317.A O no hydrogen 3.001 N/A GLU 321.A N SER 318.A O no hydrogen 3.244 N/A ALA 323.A N ARG 159.A O no hydrogen 3.267 N/A