Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4fn9_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 6.A N GLU 169.A OE2 no hydrogen 3.246 N/A SER 7.A OG SER 4.A O no hydrogen 2.800 N/A ILE 8.A N SER 4.A O no hydrogen 3.100 N/A LEU 9.A N LEU 5.A O no hydrogen 2.874 N/A GLN 10.A N ILE 6.A O no hydrogen 3.087 N/A GLN 10.A NE2 GLN 133.A OE1 no hydrogen 2.483 N/A ALA 11.A N SER 7.A O no hydrogen 3.158 N/A ILE 12.A N ILE 8.A O no hydrogen 2.989 N/A GLU 13.A N GLN 10.A O no hydrogen 3.444 N/A GLU 15.A N GLU 15.A OE1 no hydrogen 2.755 N/A ALA 19.A N ASP 99.A OD1 no hydrogen 2.965 N/A GLY 20.A N ASP 99.A OD2 no hydrogen 2.613 N/A TYR 21.A N ASP 99.A OD2 no hydrogen 3.177 N/A ASP 22.A N TYR 31.A OH no hydrogen 3.267 N/A ASN 23.A ND2 ASP 99.A O no hydrogen 2.775 N/A THR 24.A OG1 ASP 22.A OD1 no hydrogen 2.405 N/A GLN 25.A N ASP 22.A O no hydrogen 3.199 N/A GLN 25.A NE2 ASP 22.A OD2 no hydrogen 2.734 N/A THR 28.A OG1 ASN 30.A OD1 no hydrogen 3.484 N/A THR 29.A OG1 GLN 109.A O no hydrogen 2.523 N/A TYR 31.A N THR 28.A OG1 no hydrogen 3.311 N/A LEU 32.A N THR 28.A O no hydrogen 2.822 N/A LEU 33.A N THR 29.A O no hydrogen 3.055 N/A SER 34.A N ASN 30.A O no hydrogen 2.865 N/A SER 34.A OG ASN 30.A O no hydrogen 2.463 N/A SER 35.A N TYR 31.A O no hydrogen 2.970 N/A SER 35.A OG TYR 31.A O no hydrogen 2.652 N/A LEU 36.A N LEU 32.A O no hydrogen 3.093 N/A ASN 37.A N LEU 33.A O no hydrogen 3.021 N/A ARG 38.A N SER 34.A O no hydrogen 3.031 N/A LEU 39.A N SER 35.A O no hydrogen 3.115 N/A ALA 40.A N LEU 36.A O no hydrogen 2.658 N/A GLU 41.A N ASN 37.A O no hydrogen 3.135 N/A GLU 41.A N ARG 38.A O no hydrogen 2.944 N/A LYS 42.A N ARG 38.A O no hydrogen 3.197 N/A LYS 42.A NZ TYR 18.A O no hydrogen 2.890 N/A GLN 43.A N LEU 39.A O no hydrogen 2.998 N/A GLN 43.A NE2 PHE 96.A O no hydrogen 3.558 N/A LEU 44.A N ALA 40.A O no hydrogen 2.849 N/A VAL 45.A N GLU 41.A O no hydrogen 3.197 N/A SER 46.A OG GLN 43.A O no hydrogen 3.001 N/A VAL 47.A N GLN 43.A O no hydrogen 2.780 N/A VAL 48.A N LEU 44.A O no hydrogen 3.248 N/A VAL 48.A N VAL 45.A O no hydrogen 3.217 N/A LYS 49.A N VAL 45.A O no hydrogen 3.148 N/A TRP 50.A N SER 46.A O no hydrogen 2.813 N/A ALA 51.A N VAL 47.A O no hydrogen 3.080 N/A LYS 52.A N VAL 48.A O no hydrogen 3.137 N/A LYS 52.A NZ GLN 65.A OE1 no hydrogen 2.907 N/A ALA 53.A N LYS 49.A O no hydrogen 3.146 N/A LEU 54.A N ALA 51.A O no hydrogen 3.126 N/A PHE 57.A N LEU 54.A O no hydrogen 3.044 N/A ARG 58.A NH1 LYS 52.A O no hydrogen 3.475 N/A LEU 60.A N PHE 57.A O no hydrogen 2.943 N/A HIS 61.A N SER 155.A OG no hydrogen 2.887 N/A ASP 63.A N HIS 61.A ND1 no hydrogen 3.087 N/A GLN 65.A N HIS 61.A O no hydrogen 3.031 N/A GLN 65.A NE2 LEU 60.A O no hydrogen 2.900 N/A MET 66.A N LEU 62.A O no hydrogen 3.255 N/A THR 67.A N ASP 63.A O no hydrogen 2.776 N/A THR 67.A OG1 ASP 63.A O no hydrogen 2.984 N/A LEU 68.A N ASP 64.A O no hydrogen 2.874 N/A ILE 69.A N GLN 65.A O no hydrogen 3.279 N/A GLN 70.A N MET 66.A O no hydrogen 3.193 N/A TYR 71.A N THR 67.A O no hydrogen 3.031 N/A SER 72.A N LEU 68.A O no hydrogen 2.934 N/A SER 72.A OG LEU 68.A O no hydrogen 2.865 N/A TRP 73.A N ILE 69.A O no hydrogen 2.765 N/A TRP 73.A NE1 GLN 234.A OE1 no hydrogen 2.890 N/A LEU 76.A N SER 72.A O no hydrogen 2.875 N/A MET 77.A N TRP 73.A O no hydrogen 3.244 N/A ALA 78.A N MET 74.A O no hydrogen 3.067 N/A PHE 79.A N GLY 75.A O no hydrogen 2.771 N/A ALA 80.A N LEU 76.A O no hydrogen 2.924 N/A MET 81.A N MET 77.A O no hydrogen 2.860 N/A GLY 82.A N ALA 78.A O no hydrogen 3.105 N/A TRP 83.A N PHE 79.A O no hydrogen 3.107 N/A ARG 84.A N ALA 80.A O no hydrogen 2.992 N/A ARG 84.A NE TYR 95.A O no hydrogen 3.026 N/A SER 85.A N MET 81.A O no hydrogen 2.849 N/A SER 85.A OG MET 81.A O no hydrogen 2.920 N/A SER 85.A OG MET 93.A O no hydrogen 3.199 N/A TYR 86.A N GLY 82.A O no hydrogen 3.041 N/A TYR 86.A OH VAL 131.A O no hydrogen 3.122 N/A LYS 87.A N TRP 83.A O no hydrogen 2.810 N/A HIS 88.A N ARG 84.A O no hydrogen 2.775 N/A HIS 88.A ND1 ARG 84.A O no hydrogen 3.147 N/A THR 89.A N SER 85.A O no hydrogen 3.160 N/A THR 89.A OG1 SER 85.A O no hydrogen 2.608 N/A THR 89.A OG1 MET 93.A O no hydrogen 2.967 N/A GLY 91.A N SER 85.A O no hydrogen 2.714 N/A GLN 92.A N THR 89.A O no hydrogen 3.048 N/A MET 93.A N THR 89.A OG1 no hydrogen 2.923 N/A LEU 94.A N PHE 102.A O no hydrogen 2.981 N/A TYR 95.A N SER 85.A OG no hydrogen 2.879 N/A ALA 97.A N LEU 100.A O no hydrogen 3.270 N/A LEU 100.A N ALA 97.A O no hydrogen 3.200 N/A PHE 102.A N LEU 94.A O no hydrogen 2.679 N/A ARG 106.A N ASN 103.A OD1 no hydrogen 3.148 N/A ARG 106.A NE ASP 27.A OD2 no hydrogen 3.126 N/A ARG 106.A NH1 ASN 23.A OD1 no hydrogen 3.102 N/A ARG 106.A NH1 ILE 101.A O no hydrogen 3.307 N/A ARG 106.A NH2 ASN 23.A OD1 no hydrogen 2.885 N/A MET 107.A N ASN 103.A O no hydrogen 3.124 N/A GLN 108.A N GLU 104.A O no hydrogen 3.101 N/A GLN 109.A N GLN 105.A O no hydrogen 3.010 N/A SER 110.A N ARG 106.A O no hydrogen 2.816 N/A SER 110.A OG MET 107.A O no hydrogen 2.418 N/A ALA 111.A N GLN 108.A O no hydrogen 3.335 N/A MET 112.A N SER 110.A OG no hydrogen 3.000 N/A TYR 113.A OH GLU 104.A OE2 no hydrogen 2.583 N/A LEU 115.A N MET 112.A O no hydrogen 2.561 N/A CYS 116.A N MET 112.A O no hydrogen 2.982 N/A CYS 116.A SG SER 110.A OG no hydrogen 3.692 N/A GLN 117.A N TYR 113.A O no hydrogen 2.960 N/A GLY 118.A N ASP 114.A O no hydrogen 3.212 N/A MET 119.A N LEU 115.A O no hydrogen 2.924 N/A GLN 120.A N CYS 116.A O no hydrogen 2.825 N/A GLN 120.A NE2 GLY 91.A O no hydrogen 3.672 N/A GLN 121.A N GLN 117.A O no hydrogen 2.818 N/A GLN 121.A N GLY 118.A O no hydrogen 3.219 N/A ILE 122.A N GLY 118.A O no hydrogen 3.222 N/A SER 123.A N MET 119.A O no hydrogen 3.276 N/A SER 123.A OG MET 119.A O no hydrogen 3.370 N/A SER 123.A OG GLN 120.A O no hydrogen 2.843 N/A GLN 124.A N GLN 120.A O no hydrogen 3.159 N/A GLN 124.A NE2 GLY 91.A O no hydrogen 3.292 N/A GLU 125.A N GLN 121.A O no hydrogen 3.190 N/A GLU 125.A N ILE 122.A O no hydrogen 3.041 N/A PHE 126.A N ILE 122.A O no hydrogen 3.231 N/A VAL 127.A N SER 123.A O no hydrogen 3.015 N/A ARG 128.A N GLN 124.A O no hydrogen 2.946 N/A LEU 129.A N GLU 125.A O no hydrogen 2.776 N/A GLN 130.A N VAL 127.A O no hydrogen 3.280 N/A GLN 130.A NE2 VAL 127.A O no hydrogen 2.805 N/A VAL 131.A N PHE 126.A O no hydrogen 3.326 N/A THR 132.A N GLU 135.A OE2 no hydrogen 2.871 N/A GLU 134.A N GLU 134.A OE1 no hydrogen 2.857 N/A GLU 135.A N THR 132.A OG1 no hydrogen 2.902 N/A PHE 136.A N THR 132.A O no hydrogen 2.830 N/A LEU 137.A N GLN 133.A O no hydrogen 3.038 N/A CYS 138.A N GLU 134.A O no hydrogen 3.205 N/A CYS 138.A SG GLU 134.A O no hydrogen 3.419 N/A MET 139.A N GLU 135.A O no hydrogen 3.032 N/A LYS 140.A N PHE 136.A O no hydrogen 3.018 N/A LYS 140.A NZ GLU 13.A OE1 no hydrogen 3.498 N/A ALA 141.A N LEU 137.A O no hydrogen 3.191 N/A ALA 141.A N CYS 138.A O no hydrogen 3.031 N/A LEU 142.A N CYS 138.A O no hydrogen 3.000 N/A LEU 143.A N MET 139.A O no hydrogen 2.812 N/A SER 146.A N LEU 143.A O no hydrogen 3.164 N/A SER 146.A OG LEU 142.A O no hydrogen 3.104 N/A VAL 148.A N LYS 244.A O no hydrogen 3.016 N/A LYS 150.A N MET 242.A O no hydrogen 2.440 N/A LYS 150.A NZ GLY 241.A O no hydrogen 3.070 N/A GLU 151.A N GLU 151.A OE1 no hydrogen 2.667 N/A GLY 152.A N PRO 149.A O no hydrogen 2.907 N/A LEU 153.A N GLN 156.A OE1 no hydrogen 3.198 N/A LYS 154.A N ASP 64.A OD1 no hydrogen 3.250 N/A LYS 154.A NZ ASP 63.A OD2 no hydrogen 2.657 N/A SER 155.A N ASP 64.A OD2 no hydrogen 3.139 N/A SER 155.A OG ASP 64.A OD2 no hydrogen 3.280 N/A SER 158.A OG ASN 59.A O no hydrogen 3.470 N/A MET 162.A N SER 158.A O no hydrogen 2.971 N/A ARG 163.A N PHE 159.A O no hydrogen 2.776 N/A ARG 163.A NH1 SER 146.A OG no hydrogen 2.891 N/A MET 164.A N ASP 160.A O no hydrogen 3.136 N/A MET 164.A N GLU 161.A O no hydrogen 2.992 N/A ASN 165.A N GLU 161.A O no hydrogen 3.106 N/A TYR 166.A N MET 162.A O no hydrogen 3.149 N/A TYR 166.A OH PRO 55.A O no hydrogen 2.496 N/A ILE 167.A N ARG 163.A O no hydrogen 3.252 N/A LYS 168.A N MET 164.A O no hydrogen 2.676 N/A GLU 169.A N ASN 165.A O no hydrogen 2.664 N/A LEU 170.A N TYR 166.A O no hydrogen 2.837 N/A ASN 171.A N ILE 167.A O no hydrogen 3.157 N/A ARG 172.A N LYS 168.A O no hydrogen 2.815 N/A ALA 173.A N GLU 169.A O no hydrogen 2.989 N/A ILE 174.A N LEU 170.A O no hydrogen 3.203 N/A ALA 175.A N ASN 171.A O no hydrogen 2.904 N/A LYS 176.A NZ GLU 134.A OE2 no hydrogen 2.725 N/A LYS 177.A N ILE 174.A O no hydrogen 3.435 N/A GLU 178.A N ALA 175.A O no hydrogen 2.885 N/A ASN 180.A N GLN 183.A OE1 no hydrogen 3.081 N/A ALA 182.A N ASN 180.A OD1 no hydrogen 3.053 N/A GLN 183.A N ASN 180.A OD1 no hydrogen 3.070 N/A ASN 184.A N ASN 180.A O no hydrogen 2.910 N/A TRP 185.A N SER 181.A O no hydrogen 2.857 N/A GLN 186.A N ALA 182.A O no hydrogen 3.054 N/A ARG 187.A N GLN 183.A O no hydrogen 2.734 N/A ARG 187.A NE GLU 135.A OE1 no hydrogen 2.850 N/A ARG 187.A NH1 LEU 129.A O no hydrogen 2.550 N/A ARG 187.A NH2 LEU 129.A O no hydrogen 3.166 N/A ARG 187.A NH2 GLN 130.A O no hydrogen 3.102 N/A ARG 187.A NH2 GLU 135.A OE1 no hydrogen 3.255 N/A ARG 187.A NH2 GLU 135.A OE2 no hydrogen 2.451 N/A PHE 188.A N ASN 184.A O no hydrogen 2.838 N/A TYR 189.A N TRP 185.A O no hydrogen 2.972 N/A GLN 190.A N GLN 186.A O no hydrogen 2.943 N/A LEU 191.A N ARG 187.A O no hydrogen 2.742 N/A THR 192.A N PHE 188.A O no hydrogen 3.187 N/A THR 192.A OG1 PHE 188.A O no hydrogen 2.994 N/A THR 192.A OG1 TYR 189.A O no hydrogen 2.871 N/A LYS 193.A N TYR 189.A O no hydrogen 2.902 N/A LYS 193.A NZ HIS 249.A O no hydrogen 3.292 N/A LEU 194.A N GLN 190.A O no hydrogen 3.128 N/A LEU 195.A N LEU 191.A O no hydrogen 2.855 N/A ASP 196.A N THR 192.A O no hydrogen 2.763 N/A SER 197.A N LYS 193.A O no hydrogen 3.120 N/A SER 197.A OG LEU 194.A O no hydrogen 2.886 N/A MET 198.A N LEU 195.A O no hydrogen 2.634 N/A HIS 199.A N ASP 196.A O no hydrogen 3.229 N/A HIS 199.A ND1 ASP 196.A O no hydrogen 2.990 N/A VAL 202.A N MET 198.A O no hydrogen 2.711 N/A GLY 203.A N HIS 199.A O no hydrogen 2.618 N/A GLY 204.A N ASP 200.A O no hydrogen 3.300 N/A LEU 205.A N LEU 201.A O no hydrogen 2.957 N/A LEU 206.A N VAL 202.A O no hydrogen 2.806 N/A GLN 207.A N GLY 203.A O no hydrogen 2.985 N/A PHE 208.A N GLY 204.A O no hydrogen 3.172 N/A CYS 209.A N LEU 205.A O no hydrogen 2.848 N/A PHE 210.A N LEU 206.A O no hydrogen 2.630 N/A TYR 211.A N GLN 207.A O no hydrogen 2.892 N/A THR 212.A N PHE 208.A O no hydrogen 3.030 N/A THR 212.A OG1 PHE 208.A O no hydrogen 3.033 N/A THR 212.A OG1 CYS 209.A O no hydrogen 2.852 N/A PHE 213.A N CYS 209.A O no hydrogen 2.867 N/A VAL 214.A N PHE 210.A O no hydrogen 3.054 N/A GLN 215.A N TYR 211.A O no hydrogen 2.995 N/A SER 216.A N PHE 213.A O no hydrogen 3.469 N/A SER 216.A OG PHE 213.A O no hydrogen 3.436 N/A GLN 217.A N GLN 217.A OE1 no hydrogen 3.292 N/A LEU 219.A N GLN 215.A O no hydrogen 2.663 N/A SER 220.A N GLN 217.A O no hydrogen 3.380 N/A VAL 221.A N SER 216.A O no hydrogen 3.234 N/A VAL 228.A N PRO 224.A O no hydrogen 3.117 N/A VAL 228.A N GLU 225.A O no hydrogen 2.724 N/A GLU 229.A N GLU 229.A OE1 no hydrogen 1.910 N/A ILE 231.A N LEU 227.A O no hydrogen 3.351 N/A SER 232.A N VAL 228.A O no hydrogen 2.749 N/A SER 232.A OG VAL 228.A O no hydrogen 3.100 N/A ALA 233.A N GLU 229.A O no hydrogen 2.738 N/A GLN 234.A N ILE 230.A O no hydrogen 2.916 N/A LEU 235.A N ILE 231.A O no hydrogen 2.776 N/A LYS 237.A NZ GLN 70.A OE1 no hydrogen 3.220 N/A VAL 238.A N GLN 234.A O no hydrogen 2.990 N/A LEU 239.A N LEU 235.A O no hydrogen 2.942 N/A ALA 240.A N PRO 236.A O no hydrogen 2.872 N/A GLY 241.A N VAL 238.A O no hydrogen 2.703 N/A MET 242.A N LYS 237.A O no hydrogen 2.941 N/A LYS 244.A N VAL 148.A O no hydrogen 2.620 N/A LEU 246.A N SER 146.A O no hydrogen 2.533 N/A PHE 248.A N ASP 196.A OD2 no hydrogen 2.385 N/A HIS 249.A N ASP 196.A OD2 no hydrogen 3.393 N/A LYS 250.A N HIS 249.A ND1 no hydrogen 3.054 N/A