Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4fv0_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 4.A N GLN 7.A O no hydrogen 2.879 N/A GLN 7.A N VAL 4.A O no hydrogen 3.052 N/A PHE 9.A N GLU 2.A O no hydrogen 3.070 N/A ASP 10.A N TYR 92.A OH no hydrogen 3.182 N/A ARG 14.A NE ASP 34.A OD1 no hydrogen 3.056 N/A ARG 14.A NH2 ASP 34.A OD2 no hydrogen 3.212 N/A TYR 15.A OH ASP 78.A OD2 no hydrogen 2.667 N/A THR 16.A N TYR 33.A O no hydrogen 3.100 N/A THR 16.A OG1 ASN 17.A OD1 no hydrogen 3.063 N/A SER 19.A N SER 31.A O no hydrogen 3.109 N/A TYR 20.A OH GLU 23.A OE2 no hydrogen 3.306 N/A ILE 21.A N VAL 29.A O no hydrogen 2.905 N/A GLY 22.A N VAL 29.A O no hydrogen 3.292 N/A GLY 24.A N GLY 27.A O no hydrogen 2.694 N/A VAL 29.A N GLY 22.A O no hydrogen 2.991 N/A CYS 30.A N ILE 43.A O no hydrogen 2.925 N/A SER 31.A N SER 19.A O no hydrogen 2.838 N/A ALA 32.A N VAL 41.A O no hydrogen 2.910 N/A TYR 33.A N THR 16.A O no hydrogen 2.702 N/A ASP 34.A N VAL 39.A O no hydrogen 2.795 N/A ASN 35.A N ARG 14.A O no hydrogen 2.810 N/A ASN 35.A ND2 ARG 14.A O no hydrogen 2.748 N/A ASN 35.A ND2 THR 16.A OG1 no hydrogen 2.765 N/A VAL 36.A N ASP 34.A OD1 no hydrogen 2.872 N/A ASN 37.A N ASP 34.A OD1 no hydrogen 3.129 N/A LYS 38.A NZ ASN 35.A O no hydrogen 2.763 N/A ARG 40.A NH1 ASN 17.A O no hydrogen 3.001 N/A ARG 40.A NH2 ASN 17.A O no hydrogen 2.932 N/A ARG 40.A NH2 SER 31.A OG no hydrogen 2.740 N/A VAL 41.A N ALA 32.A O no hydrogen 2.763 N/A ALA 42.A N GLN 95.A O no hydrogen 2.807 N/A ILE 43.A N CYS 30.A O no hydrogen 2.726 N/A LYS 44.A N ILE 93.A O no hydrogen 2.964 N/A LYS 45.A N MET 28.A O no hydrogen 2.665 N/A LYS 45.A NZ VAL 8.A O no hydrogen 2.571 N/A ILE 46.A N VAL 91.A O no hydrogen 2.872 N/A SER 47.A OG ASP 90.A OD2 no hydrogen 2.608 N/A HIS 51.A N PRO 48.A O no hydrogen 3.337 N/A CYS 55.A N HIS 51.A O no hydrogen 3.111 N/A CYS 55.A SG PRO 48.A O no hydrogen 3.210 N/A CYS 55.A SG HIS 51.A O no hydrogen 3.487 N/A GLN 56.A N GLN 52.A O no hydrogen 2.985 N/A ARG 57.A N THR 53.A O no hydrogen 3.082 N/A THR 58.A N TYR 54.A O no hydrogen 3.123 N/A THR 58.A OG1 TYR 54.A O no hydrogen 2.709 N/A LEU 59.A N CYS 55.A O no hydrogen 2.943 N/A ARG 60.A N GLN 56.A O no hydrogen 2.909 N/A ARG 60.A NH1 ALA 159.A O no hydrogen 3.336 N/A GLU 61.A N ARG 57.A O no hydrogen 3.058 N/A ILE 62.A N THR 58.A O no hydrogen 2.917 N/A LYS 63.A N LEU 59.A O no hydrogen 2.842 N/A ILE 64.A N ARG 60.A O no hydrogen 3.030 N/A LEU 65.A N GLU 61.A O no hydrogen 2.983 N/A LEU 66.A N ILE 62.A O no hydrogen 3.014 N/A ARG 67.A N LYS 63.A O no hydrogen 3.136 N/A ARG 67.A N ILE 64.A O no hydrogen 3.079 N/A PHE 68.A N ILE 64.A O no hydrogen 2.886 N/A ARG 69.A N TYR 129.A OH no hydrogen 3.123 N/A ASN 72.A N HIS 70.A ND1 no hydrogen 2.933 N/A ASN 72.A ND2 LEU 152.A O no hydrogen 3.101 N/A ILE 73.A N HIS 70.A O no hydrogen 3.227 N/A ILE 74.A N ILE 154.A O no hydrogen 2.890 N/A ASN 77.A N VAL 94.A O no hydrogen 2.823 N/A ASN 77.A ND2 ASP 96.A OD1 no hydrogen 2.900 N/A ILE 80.A N TYR 92.A O no hydrogen 2.785 N/A ARG 81.A NE THR 334.A OG1 no hydrogen 2.929 N/A ARG 81.A NH1 ALA 82.A O no hydrogen 3.077 N/A ARG 81.A NH2 PHE 331.A O no hydrogen 2.758 N/A THR 84.A OG1 GLN 87.A OE1 no hydrogen 2.795 N/A GLU 86.A N GLU 86.A OE1 no hydrogen 2.842 N/A GLN 87.A N THR 84.A O no hydrogen 3.256 N/A GLN 87.A N THR 84.A OG1 no hydrogen 3.185 N/A MET 88.A N ILE 85.A O no hydrogen 3.309 N/A VAL 91.A N ILE 46.A O no hydrogen 2.935 N/A TYR 92.A N ILE 80.A O no hydrogen 2.774 N/A TYR 92.A OH ASP 10.A OD2 no hydrogen 2.979 N/A ILE 93.A N LYS 44.A O no hydrogen 2.956 N/A VAL 94.A N ASP 78.A O no hydrogen 2.791 N/A GLN 95.A N ALA 42.A O no hydrogen 2.915 N/A THR 100.A N LEU 147.A O no hydrogen 3.006 N/A THR 100.A OG1 ASP 101.A O no hydrogen 3.336 N/A LEU 102.A N LEU 145.A O no hydrogen 2.872 N/A LYS 104.A N ASP 101.A OD1 no hydrogen 2.956 N/A LEU 105.A N ASP 101.A O no hydrogen 3.096 N/A LEU 106.A N LEU 102.A O no hydrogen 2.882 N/A LYS 107.A N TYR 103.A O no hydrogen 3.248 N/A LYS 107.A N LYS 104.A O no hydrogen 3.237 N/A THR 108.A N LEU 105.A O no hydrogen 3.250 N/A THR 108.A OG1 LYS 104.A O no hydrogen 3.493 N/A GLN 109.A N LEU 105.A O no hydrogen 2.765 N/A SER 112.A OG HIS 115.A ND1 no hydrogen 2.728 N/A HIS 115.A N SER 112.A OG no hydrogen 3.152 N/A HIS 115.A ND1 SER 112.A OG no hydrogen 2.728 N/A ILE 116.A N SER 112.A O no hydrogen 3.062 N/A CYS 117.A N ASN 113.A O no hydrogen 2.934 N/A CYS 117.A SG TYR 299.A O no hydrogen 3.303 N/A TYR 118.A N ASP 114.A O no hydrogen 2.992 N/A PHE 119.A N HIS 115.A O no hydrogen 2.867 N/A LEU 120.A N ILE 116.A O no hydrogen 2.846 N/A TYR 121.A N CYS 117.A O no hydrogen 2.937 N/A TYR 121.A OH GLU 309.A OE2 no hydrogen 2.590 N/A GLN 122.A N TYR 118.A O no hydrogen 3.051 N/A GLN 122.A NE2 TYR 118.A O no hydrogen 3.472 N/A ILE 123.A N PHE 119.A O no hydrogen 2.965 N/A LEU 124.A N LEU 120.A O no hydrogen 3.056 N/A ARG 125.A N TYR 121.A O no hydrogen 2.843 N/A ARG 125.A NE ASP 308.A O no hydrogen 2.828 N/A ARG 125.A NH1 GLU 71.A OE2 no hydrogen 3.095 N/A ARG 125.A NH1 ASN 72.A OD1 no hydrogen 2.858 N/A ARG 125.A NH2 GLU 71.A OE2 no hydrogen 3.426 N/A ARG 125.A NH2 ASP 308.A O no hydrogen 2.883 N/A GLY 126.A N GLN 122.A O no hydrogen 2.985 N/A LEU 127.A N ILE 123.A O no hydrogen 2.787 N/A LYS 128.A N LEU 124.A O no hydrogen 2.761 N/A LYS 128.A NZ GLU 309.A O no hydrogen 2.727 N/A ILE 130.A N GLY 126.A O no hydrogen 3.211 N/A HIS 131.A N LEU 127.A O no hydrogen 2.977 N/A HIS 131.A NE2 ASP 198.A OD2 no hydrogen 2.762 N/A SER 132.A N LYS 128.A O no hydrogen 2.859 N/A SER 132.A OG LYS 128.A O no hydrogen 3.485 N/A SER 132.A OG TYR 129.A O no hydrogen 2.518 N/A ALA 133.A N TYR 129.A O no hydrogen 3.201 N/A ALA 133.A N ILE 130.A O no hydrogen 3.089 N/A ASN 134.A N HIS 131.A O no hydrogen 2.954 N/A ASN 134.A ND2 ALA 162.A O no hydrogen 3.643 N/A VAL 135.A N ILE 130.A O no hydrogen 3.185 N/A LEU 136.A N ARG 160.A O no hydrogen 2.733 N/A HIS 137.A N ASP 198.A OD2 no hydrogen 2.980 N/A ARG 138.A N ASP 198.A OD1 no hydrogen 2.879 N/A ARG 138.A NE GLY 192.A O no hydrogen 3.056 N/A ARG 138.A NH1 LEU 158.A O no hydrogen 2.756 N/A ARG 138.A NH2 LYS 191.A O no hydrogen 3.379 N/A ASP 139.A N HIS 137.A ND1 no hydrogen 2.945 N/A LYS 141.A NZ THR 178.A OG1 no hydrogen 2.745 N/A ASN 144.A N LYS 141.A O no hydrogen 2.907 N/A ASN 144.A ND2 ASP 139.A O no hydrogen 2.720 N/A LEU 145.A N PRO 142.A O no hydrogen 3.157 N/A LEU 146.A N LYS 153.A O no hydrogen 2.855 N/A LEU 147.A N THR 100.A O no hydrogen 2.819 N/A ASN 148.A N ASP 151.A O no hydrogen 3.042 N/A ASN 148.A ND2 ASP 151.A OD2 no hydrogen 2.793 N/A THR 149.A OG1 GLU 99.A OE1 no hydrogen 2.633 N/A THR 150.A N ASN 148.A OD1 no hydrogen 3.097 N/A THR 150.A OG1 ASN 148.A OD1 no hydrogen 3.080 N/A THR 150.A OG1 ASP 151.A OD2 no hydrogen 2.965 N/A LEU 152.A N GLN 122.A OE1 no hydrogen 2.795 N/A LYS 153.A N LEU 146.A O no hydrogen 2.777 N/A LYS 153.A NZ GLU 71.A O no hydrogen 2.863 N/A ILE 154.A N ASN 72.A O no hydrogen 2.787 N/A PHE 156.A N GLU 61.A OE2 no hydrogen 3.016 N/A GLY 157.A N ASP 155.A OD2 no hydrogen 3.381 N/A ALA 159.A N PHE 156.A O no hydrogen 3.206 N/A ARG 160.A N LEU 136.A O no hydrogen 3.053 N/A ALA 162.A N ASN 134.A O no hydrogen 2.817 N/A ASP 163.A N TYR 193.A O no hydrogen 2.844 N/A HIS 166.A N ASP 163.A O no hydrogen 3.241 N/A HIS 166.A ND1 ASP 163.A OD1 no hydrogen 2.818 N/A THR 169.A N ASN 189.A O no hydrogen 3.064 N/A THR 169.A OG1 THR 173.A OG1 no hydrogen 3.053 N/A THR 173.A OG1 THR 169.A OG1 no hydrogen 3.053 N/A THR 173.A OG1 GLY 170.A O no hydrogen 2.833 N/A THR 178.A N ASP 139.A OD2 no hydrogen 3.257 N/A THR 178.A OG1 ASP 139.A OD2 no hydrogen 2.875 N/A ARG 179.A NH1 GLY 218.A O no hydrogen 3.274 N/A TRP 180.A NE1 GLY 218.A O no hydrogen 2.852 N/A TYR 181.A N THR 178.A O no hydrogen 3.249 N/A TYR 181.A OH GLU 208.A OE1 no hydrogen 2.637 N/A TYR 181.A OH GLU 208.A OE2 no hydrogen 3.425 N/A ARG 182.A N ARG 179.A O no hydrogen 3.157 N/A ARG 182.A NE ALA 177.A O no hydrogen 2.793 N/A ARG 182.A NH2 ALA 177.A O no hydrogen 2.796 N/A GLU 185.A N GLU 185.A OE1 no hydrogen 2.855 N/A ILE 186.A N ALA 183.A O no hydrogen 3.076 N/A MET 187.A N PRO 184.A O no hydrogen 3.162 N/A LEU 188.A N GLU 185.A O no hydrogen 2.972 N/A ASN 189.A N GLU 185.A O no hydrogen 2.775 N/A SER 190.A N GLU 185.A O no hydrogen 2.916 N/A SER 190.A OG ASP 167.A OD1 no hydrogen 3.115 N/A SER 190.A OG ASP 167.A OD2 no hydrogen 2.682 N/A LYS 191.A N ASP 167.A O no hydrogen 2.787 N/A LYS 191.A NZ HIS 166.A O no hydrogen 3.438 N/A GLY 192.A N SER 190.A OG no hydrogen 3.136 N/A TYR 193.A N ASP 167.A OD1 no hydrogen 2.759 N/A THR 194.A OG1 SER 196.A OG no hydrogen 2.719 N/A LYS 195.A NZ HIS 131.A O no hydrogen 2.902 N/A SER 196.A OG THR 194.A OG1 no hydrogen 2.719 N/A ILE 197.A N THR 194.A O no hydrogen 3.127 N/A ASP 198.A N LYS 195.A O no hydrogen 3.075 N/A TRP 200.A N SER 196.A O no hydrogen 3.174 N/A SER 201.A N ILE 197.A O no hydrogen 3.340 N/A SER 201.A OG TYR 181.A O no hydrogen 2.884 N/A SER 201.A OG ILE 197.A O no hydrogen 3.290 N/A VAL 202.A N ASP 198.A O no hydrogen 2.998 N/A GLY 203.A N ILE 199.A O no hydrogen 2.977 N/A CYS 204.A N TRP 200.A O no hydrogen 3.045 N/A CYS 204.A SG TRP 180.A O no hydrogen 3.880 N/A CYS 204.A SG TRP 200.A O no hydrogen 3.493 N/A ILE 205.A N SER 201.A O no hydrogen 3.026 N/A LEU 206.A N VAL 202.A O no hydrogen 2.864 N/A ALA 207.A N GLY 203.A O no hydrogen 3.001 N/A GLU 208.A N CYS 204.A O no hydrogen 3.094 N/A MET 209.A N ILE 205.A O no hydrogen 2.882 N/A LEU 210.A N LEU 206.A O no hydrogen 3.046 N/A SER 211.A N ALA 207.A O no hydrogen 3.280 N/A SER 211.A OG ALA 207.A O no hydrogen 3.384 N/A ASN 212.A N GLU 208.A O no hydrogen 2.632 N/A ASN 212.A ND2 LEU 106.A O no hydrogen 2.763 N/A ASN 212.A ND2 GLN 109.A O no hydrogen 2.690 N/A GLY 218.A N PHE 216.A O no hydrogen 2.827 N/A LYS 219.A N ASP 223.A OD2 no hydrogen 2.715 N/A TYR 221.A OH THR 173.A O no hydrogen 2.508 N/A GLN 224.A N HIS 220.A O no hydrogen 2.930 N/A GLN 224.A NE2 PHE 216.A O no hydrogen 2.938 N/A ASN 226.A N LEU 222.A O no hydrogen 3.287 N/A HIS 227.A N ASP 223.A O no hydrogen 2.916 N/A ILE 228.A N GLN 224.A O no hydrogen 3.210 N/A LEU 229.A N LEU 225.A O no hydrogen 2.953 N/A GLY 230.A N ASN 226.A O no hydrogen 3.059 N/A ILE 231.A N ILE 228.A O no hydrogen 3.146 N/A LEU 232.A N ILE 228.A O no hydrogen 2.908 N/A GLY 233.A N LEU 229.A O no hydrogen 2.899 N/A SER 234.A N LYS 257.A O no hydrogen 2.757 N/A GLN 237.A NE2.B GLN 237.A O no hydrogen 3.501 N/A GLN 237.A NE2.B ASN 241.A OD1 no hydrogen 2.756 N/A ASP 239.A N SER 236.A OG no hydrogen 3.100 N/A LEU 240.A N SER 236.A O no hydrogen 2.958 N/A ASN 241.A N GLN 237.A O no hydrogen 2.891 N/A ALA 247.A N ASN 244.A OD1 no hydrogen 3.216 N/A ARG 248.A N ASN 244.A O no hydrogen 2.980 N/A ARG 248.A NE ILE 242.A O no hydrogen 2.738 N/A ARG 248.A NH2 ILE 242.A O no hydrogen 3.194 N/A ASN 249.A N LEU 245.A O no hydrogen 2.794 N/A TYR 250.A N LYS 246.A O no hydrogen 3.065 N/A LEU 251.A N ALA 247.A O no hydrogen 3.266 N/A LEU 252.A N ARG 248.A O no hydrogen 3.035 N/A SER 253.A N ASN 249.A O no hydrogen 3.020 N/A SER 253.A N TYR 250.A O no hydrogen 3.219 N/A SER 253.A OG TYR 250.A O no hydrogen 2.642 N/A LEU 254.A N LEU 251.A O no hydrogen 3.315 N/A LYS 257.A N SER 234.A OG no hydrogen 2.825 N/A LYS 259.A NZ ASP 278.A OD1 no hydrogen 3.491 N/A VAL 260.A N ILE 231.A O no hydrogen 2.823 N/A TRP 262.A NE1 ASP 278.A OD1 no hydrogen 2.863 N/A ARG 264.A N PRO 261.A O no hydrogen 3.052 N/A LEU 265.A N PRO 261.A O no hydrogen 3.282 N/A PHE 266.A N TRP 262.A O no hydrogen 2.826 N/A ALA 269.A N PHE 266.A O no hydrogen 3.237 N/A LYS 272.A N ASP 270.A OD2 no hydrogen 2.809 N/A ALA 273.A N ASP 270.A OD2 no hydrogen 3.379 N/A LEU 274.A N ASP 270.A O no hydrogen 3.209 N/A ASP 275.A N SER 271.A O no hydrogen 3.033 N/A LEU 276.A N LYS 272.A O no hydrogen 3.122 N/A LEU 277.A N ALA 273.A O no hydrogen 2.888 N/A ASP 278.A N LEU 274.A O no hydrogen 2.973 N/A LYS 279.A N ASP 275.A O no hydrogen 3.363 N/A LYS 279.A NZ ASP 275.A OD1 no hydrogen 3.038 N/A LYS 279.A NZ ASP 275.A OD2 no hydrogen 2.857 N/A MET 280.A N LEU 276.A O no hydrogen 2.996 N/A LEU 281.A N LEU 277.A O no hydrogen 2.773 N/A THR 282.A OG1 ASP 278.A O no hydrogen 2.967 N/A THR 282.A OG1 LYS 279.A O no hydrogen 3.111 N/A ASN 284.A ND2 ASP 239.A OD1 no hydrogen 2.914 N/A HIS 286.A N ASN 284.A OD1 no hydrogen 2.940 N/A LYS 287.A N ASN 284.A O no hydrogen 3.185 N/A LYS 287.A NZ ASP 239.A OD1 no hydrogen 2.837 N/A ARG 288.A N ASN 284.A O no hydrogen 3.077 N/A ARG 288.A NE THR 282.A O no hydrogen 2.811 N/A ARG 288.A NH1 GLU 185.A OE2 no hydrogen 2.803 N/A ARG 288.A NH1 SER 196.A O no hydrogen 3.025 N/A ARG 288.A NH2 GLU 185.A OE1 no hydrogen 2.800 N/A ARG 288.A NH2 GLU 185.A OE2 no hydrogen 3.522 N/A ARG 288.A NH2 THR 282.A O no hydrogen 2.993 N/A ARG 288.A NH2 PHE 283.A O no hydrogen 3.047 N/A ILE 289.A N LYS 279.A O no hydrogen 3.184 N/A GLU 290.A N GLN 293.A OE1 no hydrogen 2.887 N/A ALA 294.A N GLU 290.A O no hydrogen 3.006 N/A LEU 295.A N VAL 291.A O no hydrogen 3.025 N/A ALA 296.A N GLU 292.A O no hydrogen 3.178 N/A HIS 297.A N ALA 294.A O no hydrogen 3.141 N/A HIS 297.A NE2 ASP 275.A OD2 no hydrogen 2.606 N/A TYR 299.A N HIS 297.A ND1 no hydrogen 2.990 N/A TYR 299.A OH ASN 113.A OD1 no hydrogen 2.938 N/A LEU 300.A N HIS 297.A O no hydrogen 2.961 N/A GLU 301.A N PRO 298.A O no hydrogen 3.257 N/A TYR 303.A N LEU 300.A O no hydrogen 2.918 N/A TYR 304.A N LEU 300.A O no hydrogen 2.882 N/A ASP 305.A N GLU 309.A OE2 no hydrogen 2.887 N/A SER 307.A OG ASP 305.A OD1 no hydrogen 2.858 N/A ASP 308.A N ASP 305.A O no hydrogen 2.807 N/A GLU 309.A N PRO 306.A O no hydrogen 3.214 N/A ALA 312.A N SER 132.A OG no hydrogen 2.814 N/A PHE 316.A N ALA 133.A O no hydrogen 2.681 N/A LYS 323.A NZ GLU 324.A OE2 no hydrogen 3.079 N/A LEU 326.A N PRO 322.A O no hydrogen 2.995 N/A LYS 327.A N LYS 323.A O no hydrogen 2.776 N/A LYS 327.A NZ ILE 85.A O no hydrogen 2.802 N/A LYS 327.A NZ MET 88.A O no hydrogen 2.851 N/A GLU 328.A N GLU 324.A O no hydrogen 3.262 N/A LEU 329.A N LYS 325.A O no hydrogen 2.887 N/A ILE 330.A N LEU 326.A O no hydrogen 2.772 N/A PHE 331.A N LYS 327.A O no hydrogen 2.838 N/A GLU 332.A N GLU 328.A O no hydrogen 2.940 N/A GLU 333.A N LEU 329.A O no hydrogen 2.822 N/A THR 334.A N ILE 330.A O no hydrogen 3.057 N/A THR 334.A OG1 ILE 330.A O no hydrogen 2.911 N/A THR 334.A OG1 PHE 331.A O no hydrogen 3.109 N/A ALA 335.A N GLU 332.A O no hydrogen 3.349 N/A PHE 337.A N THR 334.A O no hydrogen 3.402 N/A GLN 338.A N ALA 335.A O no hydrogen 3.093 N/A GLN 338.A NE2 ARG 81.A O no hydrogen 3.265 N/A TYR 341.A N PRO 339.A O no hydrogen 2.977 N/A