Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4g5q_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 4.A N HIS 165.A O no hydrogen 2.764 N/A LYS 5.A N THR 189.A OG1 no hydrogen 2.828 N/A LYS 5.A NZ HIS 183.A O no hydrogen 2.779 N/A LYS 5.A NZ GLU 186.A O no hydrogen 2.643 N/A LEU 6.A N LYS 167.A O no hydrogen 2.745 N/A LEU 7.A N ALA 190.A O no hydrogen 3.156 N/A LEU 8.A N PHE 169.A O no hydrogen 2.951 N/A LEU 9.A N ILE 192.A O no hydrogen 3.042 N/A SER 14.A OG ALA 11.A O no hydrogen 2.703 N/A LYS 16.A NZ GLY 10.A O no hydrogen 2.658 N/A ILE 19.A N GLY 15.A O no hydrogen 2.986 N/A VAL 20.A N LYS 16.A O no hydrogen 3.228 N/A LYS 21.A N SER 17.A O no hydrogen 3.003 N/A LYS 21.A NZ LEU 145.A O no hydrogen 2.730 N/A LYS 21.A NZ THR 147.A O no hydrogen 2.987 N/A GLN 22.A N THR 18.A O no hydrogen 2.837 N/A GLN 22.A NE2 ALA 296.A O no hydrogen 2.529 N/A MET 23.A N ILE 19.A O no hydrogen 3.041 N/A LYS 24.A N VAL 20.A O no hydrogen 3.321 N/A LYS 24.A NZ GLU 35.A OE2 no hydrogen 3.332 N/A ILE 25.A N LYS 21.A O no hydrogen 3.044 N/A ILE 26.A N GLN 22.A O no hydrogen 2.768 N/A HIS 27.A N MET 23.A O no hydrogen 2.674 N/A GLU 28.A N MET 23.A O no hydrogen 3.270 N/A GLY 30.A N LYS 24.A O no hydrogen 3.044 N/A TYR 31.A N GLN 141.A OE1 no hydrogen 2.545 N/A SER 32.A N GLU 35.A OE1 no hydrogen 3.105 N/A SER 32.A OG GLU 35.A OE1 no hydrogen 3.291 N/A CYS 36.A N SER 32.A O no hydrogen 2.961 N/A CYS 36.A SG TYR 31.A O no hydrogen 3.905 N/A CYS 36.A SG SER 32.A O no hydrogen 3.841 N/A LYS 37.A N GLU 33.A O no hydrogen 3.106 N/A GLN 38.A N GLU 34.A O no hydrogen 3.142 N/A TYR 39.A N CYS 36.A O no hydrogen 3.219 N/A LYS 40.A N LYS 37.A O no hydrogen 3.131 N/A VAL 43.A N TYR 39.A O no hydrogen 2.771 N/A TYR 44.A N LYS 40.A O no hydrogen 3.027 N/A TYR 44.A OH ILE 132.A O no hydrogen 2.802 N/A SER 45.A N ALA 41.A O no hydrogen 2.876 N/A SER 45.A OG ALA 41.A O no hydrogen 3.048 N/A ASN 46.A N VAL 42.A O no hydrogen 2.860 N/A ASN 46.A ND2 ARG 148.A O no hydrogen 3.306 N/A THR 47.A N VAL 43.A O no hydrogen 3.081 N/A THR 47.A OG1 VAL 43.A O no hydrogen 2.620 N/A ILE 48.A N TYR 44.A O no hydrogen 2.937 N/A GLN 49.A N SER 45.A O no hydrogen 2.700 N/A SER 50.A N ASN 46.A O no hydrogen 2.761 N/A SER 50.A OG ASN 46.A O no hydrogen 2.821 N/A ILE 51.A N THR 47.A O no hydrogen 3.149 N/A ILE 52.A N ILE 48.A O no hydrogen 3.056 N/A ALA 53.A N GLN 49.A O no hydrogen 3.014 N/A ILE 54.A N SER 50.A O no hydrogen 3.301 N/A ILE 55.A N ILE 51.A O no hydrogen 2.921 N/A ARG 56.A N ILE 52.A O no hydrogen 2.766 N/A ALA 57.A N ALA 53.A O no hydrogen 3.045 N/A MET 58.A N ILE 54.A O no hydrogen 3.090 N/A MET 58.A N ILE 55.A O no hydrogen 2.992 N/A LEU 61.A N ALA 57.A O no hydrogen 2.892 N/A LYS 62.A N GLY 59.A O no hydrogen 3.097 N/A ILE 63.A N MET 58.A O no hydrogen 2.910 N/A GLY 66.A N ASP 103.A OD2 no hydrogen 2.714 N/A ASP 67.A N ASP 103.A OD1 no hydrogen 2.950 N/A ARG 70.A N ASP 67.A O no hydrogen 3.010 N/A ARG 70.A NE ASP 73.A OD2 no hydrogen 3.041 N/A ARG 70.A NH1 ASP 73.A OD2 no hydrogen 2.662 N/A ALA 71.A N SER 68.A O no hydrogen 3.284 N/A ASP 72.A N ALA 69.A O no hydrogen 3.286 N/A ALA 74.A N ARG 70.A O no hydrogen 2.987 N/A ARG 75.A N ALA 71.A O no hydrogen 3.099 N/A GLN 76.A N ASP 72.A O no hydrogen 2.756 N/A LEU 77.A N ASP 73.A O no hydrogen 2.640 N/A PHE 78.A N ALA 74.A O no hydrogen 3.504 N/A VAL 79.A N ARG 75.A O no hydrogen 3.457 N/A LEU 80.A N GLN 76.A O no hydrogen 2.956 N/A ALA 83.A N LEU 80.A O no hydrogen 2.561 N/A GLU 85.A N GLY 82.A O no hydrogen 2.999 N/A GLY 87.A N ALA 84.A O no hydrogen 3.041 N/A LEU 93.A N THR 90.A OG1 no hydrogen 2.997 N/A ALA 94.A N THR 90.A O no hydrogen 3.208 N/A GLY 95.A N ALA 91.A O no hydrogen 2.997 N/A VAL 96.A N GLU 92.A O no hydrogen 3.142 N/A ILE 97.A N LEU 93.A O no hydrogen 3.174 N/A LYS 98.A N ALA 94.A O no hydrogen 2.819 N/A ARG 99.A N GLY 95.A O no hydrogen 2.968 N/A LEU 100.A N VAL 96.A O no hydrogen 2.957 N/A TRP 101.A N ILE 97.A O no hydrogen 2.775 N/A TRP 101.A NE1 ASN 127.A OD1 no hydrogen 2.802 N/A LYS 102.A N LYS 98.A O no hydrogen 3.195 N/A ASP 103.A N LEU 100.A O no hydrogen 2.884 N/A GLY 105.A N ASP 103.A OD2 no hydrogen 2.719 N/A VAL 106.A N ASP 103.A OD2 no hydrogen 3.468 N/A GLN 107.A N ASP 103.A O no hydrogen 3.085 N/A GLN 107.A NE2 TRP 101.A O no hydrogen 2.668 N/A ALA 108.A N SER 104.A O no hydrogen 2.870 N/A CYS 109.A N GLY 105.A O no hydrogen 3.195 N/A CYS 109.A SG ILE 54.A O no hydrogen 3.568 N/A CYS 109.A SG TYR 116.A OH no hydrogen 3.600 N/A PHE 110.A N VAL 106.A O no hydrogen 2.801 N/A ASN 111.A N GLN 107.A O no hydrogen 2.798 N/A ARG 112.A N ALA 108.A O no hydrogen 3.185 N/A ARG 112.A N CYS 109.A O no hydrogen 3.005 N/A ARG 112.A NH1 GLU 115.A OE1 no hydrogen 2.582 N/A ARG 112.A NH1 GLU 115.A OE2 no hydrogen 3.248 N/A SER 113.A N PHE 110.A O no hydrogen 3.310 N/A ARG 114.A NE ASP 201.A O no hydrogen 2.756 N/A ARG 114.A NH1 ASP 201.A O no hydrogen 2.951 N/A GLU 115.A N ARG 112.A O no hydrogen 2.926 N/A TYR 116.A N SER 113.A O no hydrogen 3.277 N/A TYR 116.A OH CYS 109.A O no hydrogen 2.990 N/A ASN 119.A ND2 SER 50.A OG no hydrogen 2.837 N/A SER 121.A N ASN 119.A OD1 no hydrogen 2.968 N/A SER 121.A OG ARG 146.A O no hydrogen 2.647 N/A ALA 122.A N ASN 119.A O no hydrogen 3.296 N/A TYR 124.A OH ASP 143.A OD1 no hydrogen 2.542 N/A TYR 125.A N SER 121.A O no hydrogen 3.101 N/A TYR 125.A OH ASP 143.A O no hydrogen 2.666 N/A LEU 126.A N ALA 122.A O no hydrogen 2.940 N/A ASN 127.A N ALA 123.A O no hydrogen 3.054 N/A ASP 128.A N TYR 125.A O no hydrogen 3.042 N/A LEU 129.A N LEU 126.A O no hydrogen 3.315 N/A ARG 131.A NH1 ASP 143.A OD2 no hydrogen 2.644 N/A ARG 131.A NH2 ASP 128.A OD2 no hydrogen 3.117 N/A ARG 131.A NH2 ASP 143.A OD1 no hydrogen 2.740 N/A ARG 131.A NH2 ASP 143.A OD2 no hydrogen 3.246 N/A ILE 132.A N ASP 128.A O no hydrogen 3.242 N/A ALA 133.A N LEU 129.A O no hydrogen 2.789 N/A GLN 134.A NE2 ASP 130.A O no hydrogen 2.821 N/A TYR 137.A N GLN 134.A O no hydrogen 3.146 N/A TYR 137.A OH ASP 143.A OD2 no hydrogen 2.856 N/A THR 140.A N ASP 143.A OD2 no hydrogen 3.079 N/A GLN 142.A NE2 THR 297.A O no hydrogen 2.818 N/A ASP 143.A N THR 140.A OG1 no hydrogen 3.140 N/A VAL 144.A N THR 140.A O no hydrogen 2.986 N/A LEU 145.A N GLN 141.A O no hydrogen 2.968 N/A ARG 146.A N GLN 142.A O no hydrogen 3.257 N/A ARG 146.A N ASP 143.A O no hydrogen 3.052 N/A THR 147.A N VAL 144.A O no hydrogen 3.234 N/A THR 147.A OG1 VAL 144.A O no hydrogen 2.664 N/A ARG 148.A N ASN 46.A OD1 no hydrogen 2.707 N/A ARG 148.A NH1 GLU 13.A OE2 no hydrogen 2.544 N/A VAL 155.A N ASP 170.A O no hydrogen 3.055 N/A THR 157.A N MET 168.A O no hydrogen 2.927 N/A THR 157.A OG1 GLU 28.A OE2 no hydrogen 2.743 N/A PHE 159.A N PHE 166.A O no hydrogen 3.102 N/A PHE 161.A N LEU 164.A O no hydrogen 3.120 N/A LYS 162.A NZ ASP 307.A OD2 no hydrogen 3.210 N/A LYS 162.A NZ ASP 311.A OD1 no hydrogen 2.567 N/A HIS 165.A N ARG 2.A O no hydrogen 3.042 N/A PHE 166.A N PHE 159.A O no hydrogen 2.781 N/A LYS 167.A N VAL 4.A O no hydrogen 2.863 N/A MET 168.A N THR 157.A O no hydrogen 2.749 N/A PHE 169.A N LEU 6.A O no hydrogen 2.833 N/A ASP 170.A N VAL 155.A O no hydrogen 2.798 N/A TRP 181.A N GLU 177.A O no hydrogen 3.299 N/A ILE 182.A N ARG 178.A O no hydrogen 3.044 N/A HIS 183.A N LYS 179.A O no hydrogen 3.084 N/A HIS 183.A ND1 GLU 186.A OE1 no hydrogen 2.575 N/A CYS 184.A N LYS 180.A O no hydrogen 3.299 N/A CYS 184.A N TRP 181.A O no hydrogen 2.939 N/A CYS 184.A SG LYS 180.A O no hydrogen 3.607 N/A PHE 185.A N ILE 182.A O no hydrogen 3.099 N/A GLU 186.A N HIS 183.A O no hydrogen 2.822 N/A THR 189.A N LYS 5.A O no hydrogen 2.862 N/A THR 189.A OG1 LYS 5.A O no hydrogen 3.390 N/A ALA 190.A N LYS 5.A O no hydrogen 3.296 N/A ILE 191.A N SER 233.A O no hydrogen 2.896 N/A ILE 192.A N LEU 7.A O no hydrogen 2.829 N/A PHE 193.A N ILE 235.A O no hydrogen 2.956 N/A CYS 194.A N LEU 9.A O no hydrogen 2.782 N/A CYS 194.A SG ILE 192.A O no hydrogen 4.008 N/A VAL 195.A N PHE 237.A O no hydrogen 2.925 N/A LEU 197.A N ASN 239.A O no hydrogen 2.917 N/A ASP 199.A N ALA 196.A O no hydrogen 3.191 N/A TYR 200.A N LEU 197.A O no hydrogen 3.073 N/A TYR 200.A OH SER 251.A O no hydrogen 2.565 N/A LEU 202.A N ASP 199.A O no hydrogen 3.206 N/A VAL 203.A N ARG 114.A O no hydrogen 3.245 N/A ALA 205.A N GLU 208.A OE1 no hydrogen 2.944 N/A GLU 208.A N ALA 205.A O no hydrogen 3.152 N/A ASN 211.A ND2 CYS 256.A O no hydrogen 3.217 N/A ARG 212.A NH2 GLY 12.A O no hydrogen 3.434 N/A HIS 214.A N ASN 211.A OD1 no hydrogen 3.057 N/A HIS 214.A ND1 ASN 211.A OD1 no hydrogen 2.752 N/A GLU 215.A N ASN 211.A O no hydrogen 3.036 N/A SER 216.A N ARG 212.A O no hydrogen 2.898 N/A MET 217.A N MET 213.A O no hydrogen 2.872 N/A LYS 218.A N HIS 214.A O no hydrogen 2.860 N/A LEU 219.A N GLU 215.A O no hydrogen 3.094 N/A PHE 220.A N SER 216.A O no hydrogen 2.990 N/A ASP 221.A N MET 217.A O no hydrogen 2.696 N/A SER 222.A N LYS 218.A O no hydrogen 3.234 N/A SER 222.A N LEU 219.A O no hydrogen 3.173 N/A SER 222.A OG LEU 219.A O no hydrogen 3.150 N/A ILE 223.A N LEU 219.A O no hydrogen 3.071 N/A CYS 224.A N PHE 220.A O no hydrogen 2.883 N/A ASN 225.A N ASP 221.A O no hydrogen 3.205 N/A ASN 225.A ND2 ASP 221.A O no hydrogen 3.017 N/A ASN 225.A ND2 ASP 221.A OD1 no hydrogen 2.889 N/A ASN 225.A ND2 LEU 280.A O no hydrogen 2.900 N/A ASN 226.A N ILE 223.A O no hydrogen 3.146 N/A TRP 228.A N ASN 226.A OD1 no hydrogen 2.873 N/A PHE 229.A N ASN 226.A O no hydrogen 2.821 N/A THR 230.A OG1 LYS 227.A O no hydrogen 3.378 N/A THR 232.A N PHE 229.A O no hydrogen 2.759 N/A THR 232.A OG1 VAL 188.A O no hydrogen 3.386 N/A SER 233.A N THR 189.A O no hydrogen 3.124 N/A ILE 235.A N ILE 191.A O no hydrogen 2.887 N/A LEU 236.A N TYR 290.A O no hydrogen 2.890 N/A PHE 237.A N PHE 193.A O no hydrogen 2.745 N/A LEU 238.A N HIS 292.A O no hydrogen 2.932 N/A ASN 239.A N VAL 195.A O no hydrogen 2.733 N/A ASN 239.A ND2 SER 14.A O no hydrogen 2.872 N/A LYS 240.A NZ GLU 13.A O no hydrogen 2.908 N/A LYS 240.A NZ ASP 120.A OD2 no hydrogen 2.848 N/A LYS 241.A N THR 294.A O no hydrogen 3.272 N/A LYS 241.A NZ PHE 293.A O no hydrogen 3.478 N/A LYS 241.A NZ ASN 301.A OD1 no hydrogen 3.402 N/A LEU 243.A N ASP 242.A OD1 no hydrogen 2.901 N/A PHE 244.A N LYS 240.A O no hydrogen 2.938 N/A GLU 245.A N LYS 241.A O no hydrogen 2.965 N/A LYS 247.A N LEU 243.A O no hydrogen 3.026 N/A LYS 247.A NZ SER 198.A O no hydrogen 2.801 N/A LYS 247.A NZ ASP 201.A OD1 no hydrogen 2.512 N/A ILE 248.A N PHE 244.A O no hydrogen 3.050 N/A LYS 249.A NZ GLU 246.A OE2 no hydrogen 2.656 N/A LYS 250.A N LYS 247.A O no hydrogen 2.931 N/A SER 251.A N LYS 247.A O no hydrogen 2.750 N/A SER 251.A OG ASP 201.A OD2 no hydrogen 3.240 N/A LEU 253.A N ASN 264.A OD1 no hydrogen 3.003 N/A ILE 255.A N PRO 252.A O no hydrogen 3.146 N/A CYS 256.A N LEU 253.A O no hydrogen 2.880 N/A CYS 256.A SG ASN 211.A OD1 no hydrogen 3.949 N/A TYR 257.A N LEU 253.A O no hydrogen 2.884 N/A GLU 259.A N GLU 259.A OE1 no hydrogen 2.731 N/A TYR 260.A N TYR 257.A O no hydrogen 3.100 N/A TYR 260.A OH SER 263.A O no hydrogen 2.645 N/A SER 263.A OG GLU 268.A OE1 no hydrogen 2.682 N/A GLU 267.A N GLU 267.A OE1 no hydrogen 2.780 N/A GLU 268.A N THR 265.A OG1 no hydrogen 3.320 N/A ALA 269.A N THR 265.A O no hydrogen 3.027 N/A ALA 270.A N TYR 266.A O no hydrogen 3.035 N/A ALA 271.A N GLU 267.A O no hydrogen 3.122 N/A TYR 272.A N GLU 268.A O no hydrogen 3.058 N/A TYR 272.A OH GLU 259.A OE2 no hydrogen 2.778 N/A ILE 273.A N ALA 269.A O no hydrogen 2.979 N/A GLN 274.A N ALA 270.A O no hydrogen 3.143 N/A GLN 274.A NE2 GLU 278.A OE1 no hydrogen 3.335 N/A GLN 274.A NE2 GLU 278.A OE2 no hydrogen 2.898 N/A CYS 275.A N ALA 271.A O no hydrogen 3.246 N/A CYS 275.A SG.A ALA 271.A O no hydrogen 3.077 N/A CYS 275.A SG.B ASP 279.A OD1 no hydrogen 3.431 N/A CYS 275.A SG.B ASP 279.A OD2 no hydrogen 3.242 N/A GLN 276.A N TYR 272.A O no hydrogen 3.001 N/A GLN 276.A NE2 TYR 272.A O no hydrogen 3.096 N/A PHE 277.A N ILE 273.A O no hydrogen 3.018 N/A GLU 278.A N GLN 274.A O no hydrogen 2.832 N/A ASP 279.A N CYS 275.A O no hydrogen 2.812 N/A LEU 280.A N PHE 277.A O no hydrogen 2.756 N/A ASN 281.A N GLU 278.A O no hydrogen 3.245 N/A ASN 281.A ND2 LYS 287.A O no hydrogen 3.607 N/A LYS 282.A N ASN 225.A OD1 no hydrogen 2.862 N/A ARG 283.A N ASN 281.A OD1 no hydrogen 2.935 N/A THR 286.A N ARG 283.A O no hydrogen 2.933 N/A THR 286.A OG1 ARG 283.A O no hydrogen 3.073 N/A LYS 287.A NZ PHE 229.A O no hydrogen 3.317 N/A TYR 290.A N ILE 234.A O no hydrogen 3.022 N/A THR 291.A OG1 GLU 278.A OE2 no hydrogen 2.474 N/A HIS 292.A N LEU 236.A O no hydrogen 2.799 N/A THR 294.A N LEU 238.A O no hydrogen 2.957 N/A THR 294.A OG1 ASN 239.A OD1 no hydrogen 2.788 N/A CYS 295.A N ASN 301.A OD1 no hydrogen 2.941 N/A CYS 295.A SG ASP 242.A OD2 no hydrogen 3.556 N/A CYS 295.A SG THR 297.A OG1 no hydrogen 3.364 N/A ALA 296.A N ASN 239.A OD1 no hydrogen 2.797 N/A ASP 298.A N CYS 295.A O no hydrogen 3.036 N/A THR 299.A OG1 GLN 22.A OE1 no hydrogen 2.720 N/A ASN 301.A N ASP 298.A OD1 no hydrogen 3.357 N/A VAL 302.A N ASP 298.A O no hydrogen 3.101 N/A GLN 303.A N THR 299.A O no hydrogen 2.848 N/A PHE 304.A N LYS 300.A O no hydrogen 3.062 N/A VAL 305.A N ASN 301.A O no hydrogen 2.909 N/A PHE 306.A N VAL 302.A O no hydrogen 2.640 N/A ASP 307.A N GLN 303.A O no hydrogen 2.897 N/A ALA 308.A N PHE 304.A O no hydrogen 3.000 N/A VAL 309.A N VAL 305.A O no hydrogen 2.979 N/A THR 310.A N PHE 306.A O no hydrogen 2.831 N/A THR 310.A OG1 PHE 306.A O no hydrogen 2.969 N/A ASP 311.A N ASP 307.A O no hydrogen 3.024 N/A VAL 312.A N ALA 308.A O no hydrogen 3.257 N/A ILE 313.A N VAL 309.A O no hydrogen 3.212 N/A ILE 314.A N THR 310.A O no hydrogen 2.891 N/A LYS 315.A N ASP 311.A O no hydrogen 2.915 N/A ASN 316.A N VAL 312.A O no hydrogen 2.770 N/A ASN 317.A N ILE 313.A O no hydrogen 3.071 N/A LYS 319.A N ASN 316.A O no hydrogen 3.193 N/A