Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4g5x_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 3.A N GLU 18.A O no hydrogen 2.797 N/A TYR 4.A OH GLU 6.A OE2 no hydrogen 2.801 N/A HIS 5.A N VAL 16.A O no hydrogen 3.017 N/A LEU 7.A N ILE 14.A O no hydrogen 2.810 N/A THR 9.A N GLY 12.A O no hydrogen 2.962 N/A THR 9.A OG1 GLY 12.A O no hydrogen 2.837 N/A SER 10.A N GLU 85.A OE2 no hydrogen 2.786 N/A SER 10.A OG GLU 85.A OE1 no hydrogen 2.651 N/A SER 10.A OG GLU 85.A OE2 no hydrogen 3.453 N/A HIS 11.A N THR 9.A OG1 no hydrogen 3.025 N/A GLY 12.A N THR 9.A O no hydrogen 3.068 N/A ARG 13.A N THR 65.A OG1 no hydrogen 3.004 N/A ILE 14.A N LEU 7.A O no hydrogen 2.754 N/A ALA 15.A N SER 64.A OG no hydrogen 2.921 N/A VAL 16.A N HIS 5.A O no hydrogen 2.850 N/A ARG 17.A N ALA 55.A O no hydrogen 3.254 N/A ARG 17.A NH1 ALA 55.A O no hydrogen 3.106 N/A ARG 17.A NH1 ASP 57.A OD1 no hydrogen 2.882 N/A ARG 17.A NH1 ASP 57.A OD2 no hydrogen 3.457 N/A ARG 17.A NH2 ASP 57.A OD1 no hydrogen 3.298 N/A ARG 17.A NH2 ASP 57.A OD2 no hydrogen 2.846 N/A GLU 18.A N ASN 3.A O no hydrogen 2.857 N/A SER 19.A N VAL 53.A O no hydrogen 2.926 N/A SER 19.A OG GLY 48.A O no hydrogen 2.816 N/A SER 19.A OG TRP 51.A O no hydrogen 2.870 N/A GLY 23.A N LYS 50.A O no hydrogen 2.850 N/A LEU 26.A N ARG 52.A O no hydrogen 2.881 N/A LEU 27.A N VAL 96.A O no hydrogen 2.879 N/A MET 28.A N ILE 54.A O no hydrogen 2.848 N/A ILE 29.A N PHE 98.A O no hydrogen 2.800 N/A HIS 30.A ND1 GLY 31.A O no hydrogen 2.796 N/A ASN 32.A ND2 ALA 146.A O no hydrogen 2.917 N/A SER 33.A N HIS 61.A NE2 no hydrogen 3.103 N/A SER 33.A OG ASN 32.A OD1 no hydrogen 2.785 N/A SER 34.A N GLY 31.A O no hydrogen 3.070 N/A SER 34.A OG.A ASN 32.A O no hydrogen 3.502 N/A SER 34.A OG.B SER 35.A O no hydrogen 3.543 N/A SER 35.A OG.A ASP 57.A OD1 no hydrogen 2.859 N/A GLY 36.A N ASP 57.A OD1 no hydrogen 2.720 N/A ALA 37.A N SER 35.A OG.A no hydrogen 3.044 N/A ALA 37.A N SER 35.A OG.B no hydrogen 3.285 N/A ILE 38.A N SER 35.A O no hydrogen 2.993 N/A PHE 39.A N GLY 36.A O no hydrogen 3.068 N/A ALA 40.A N ALA 37.A O no hydrogen 3.159 N/A GLN 42.A N PHE 39.A O no hydrogen 2.937 N/A GLN 42.A NE2 PHE 250.A O no hydrogen 3.035 N/A GLN 42.A NE2 ASP 258.A OD1 no hydrogen 2.941 N/A LEU 43.A N PHE 39.A O no hydrogen 2.861 N/A GLU 44.A N ALA 40.A O no hydrogen 2.886 N/A GLY 48.A N GLN 42.A O no hydrogen 2.823 N/A LYS 49.A N GLY 45.A O no hydrogen 2.961 N/A LYS 49.A NZ GLU 46.A OE1 no hydrogen 3.532 N/A LYS 50.A N GLU 46.A O no hydrogen 3.313 N/A LYS 50.A N ILE 47.A O no hydrogen 3.262 N/A TRP 51.A N ILE 47.A O no hydrogen 2.862 N/A ARG 52.A N ALA 24.A O no hydrogen 3.227 N/A ARG 52.A NE GLU 18.A OE1 no hydrogen 2.913 N/A ARG 52.A NH2 GLU 18.A OE1 no hydrogen 3.083 N/A VAL 53.A N SER 19.A OG no hydrogen 2.965 N/A ILE 54.A N LEU 26.A O no hydrogen 2.773 N/A ALA 55.A N ARG 17.A O no hydrogen 2.805 N/A ASP 57.A N ALA 15.A O no hydrogen 2.904 N/A LEU 58.A N HIS 30.A NE2 no hydrogen 2.952 N/A GLY 60.A N THR 65.A O no hydrogen 2.886 N/A HIS 61.A N LEU 58.A O no hydrogen 2.928 N/A HIS 61.A ND1 PRO 59.A O no hydrogen 2.974 N/A LYS 63.A N ASP 57.A OD2 no hydrogen 2.794 N/A SER 64.A N HIS 61.A O no hydrogen 3.090 N/A SER 64.A OG ASP 57.A O no hydrogen 2.623 N/A THR 65.A N ARG 13.A O no hydrogen 2.965 N/A THR 65.A OG1 ASP 66.A O no hydrogen 3.083 N/A ALA 67.A N TYR 74.A OH no hydrogen 2.906 N/A ILE 68.A N HIS 11.A O no hydrogen 2.978 N/A ASP 71.A N ASP 69.A OD1 no hydrogen 3.091 N/A ARG 72.A N ASP 69.A O no hydrogen 2.967 N/A ARG 72.A NH1 SER 10.A OG no hydrogen 2.837 N/A ARG 72.A NH2 SER 10.A OG no hydrogen 3.136 N/A SER 73.A N ASP 69.A O no hydrogen 3.047 N/A SER 73.A OG ASP 69.A O no hydrogen 3.453 N/A TYR 74.A N PRO 70.A O no hydrogen 3.070 N/A TYR 74.A OH ASP 180.A OD2 no hydrogen 2.645 N/A SER 75.A N SER 73.A O no hydrogen 2.956 N/A GLU 77.A N GLU 77.A OE1 no hydrogen 2.726 N/A GLY 78.A N SER 75.A OG no hydrogen 2.827 N/A TYR 79.A N SER 75.A O no hydrogen 2.798 N/A ALA 80.A N MET 76.A O no hydrogen 3.100 N/A ASP 81.A N GLU 77.A O no hydrogen 2.917 N/A ALA 82.A N GLY 78.A O no hydrogen 2.977 N/A MET 83.A N TYR 79.A O no hydrogen 2.834 N/A THR 84.A N ALA 80.A O no hydrogen 2.970 N/A THR 84.A OG1 ALA 80.A O no hydrogen 2.768 N/A GLU 85.A N ASP 81.A O no hydrogen 2.970 N/A VAL 86.A N ALA 82.A O no hydrogen 2.911 N/A MET 87.A N MET 83.A O no hydrogen 2.954 N/A GLN 88.A N THR 84.A O no hydrogen 2.989 N/A GLN 89.A N GLU 85.A O no hydrogen 2.983 N/A GLN 89.A NE2 GLU 8.A O no hydrogen 3.060 N/A LEU 90.A N VAL 86.A O no hydrogen 2.864 N/A GLY 91.A N GLN 88.A O no hydrogen 3.011 N/A ILE 92.A N MET 87.A O no hydrogen 3.004 N/A ALA 95.A N TYR 114.A OH no hydrogen 3.091 N/A VAL 96.A N PRO 25.A O no hydrogen 3.043 N/A VAL 97.A N GLY 119.A O no hydrogen 2.874 N/A PHE 98.A N LEU 27.A O no hydrogen 2.773 N/A GLY 99.A N MET 121.A O no hydrogen 2.865 N/A TRP 100.A N ILE 29.A O no hydrogen 2.958 N/A TRP 100.A NE1 HIS 247.A O no hydrogen 2.814 N/A SER 101.A N THR 123.A O no hydrogen 2.725 N/A SER 101.A OG GLY 124.A O no hydrogen 3.462 N/A SER 101.A OG HIS 247.A NE2 no hydrogen 2.902 N/A GLY 103.A N TRP 100.A O no hydrogen 2.793 N/A GLY 104.A N SER 101.A O no hydrogen 2.796 N/A HIS 105.A N SER 101.A O no hydrogen 3.203 N/A HIS 105.A ND1 GLN 199.A OE1 no hydrogen 2.742 N/A ILE 106.A N LEU 102.A O no hydrogen 2.914 N/A GLY 107.A N GLY 103.A O no hydrogen 2.862 N/A ILE 108.A N GLY 104.A O no hydrogen 2.949 N/A GLU 109.A N.A HIS 105.A O no hydrogen 3.093 N/A GLU 109.A N.B HIS 105.A O no hydrogen 3.105 N/A MET 110.A N ILE 106.A O no hydrogen 2.884 N/A MET 110.A N GLY 107.A O no hydrogen 3.072 N/A ILE 111.A N ILE 108.A O no hydrogen 3.171 N/A ARG 113.A N MET 110.A O no hydrogen 2.983 N/A ARG 113.A NE ASP 81.A OD2.A no hydrogen 2.666 N/A ARG 113.A NH1 GLU 109.A O.A no hydrogen 2.791 N/A ARG 113.A NH1 GLU 109.A O.B no hydrogen 2.830 N/A ARG 113.A NH1 GLU 109.A OE1.A no hydrogen 2.750 N/A TYR 114.A OH ILE 92.A O no hydrogen 2.714 N/A MET 117.A N TYR 114.A O no hydrogen 3.095 N/A ARG 118.A N ALA 95.A O no hydrogen 3.066 N/A ARG 118.A NE ASP 94.A O no hydrogen 2.819 N/A ARG 118.A NH1 ASP 94.A O no hydrogen 3.451 N/A LEU 120.A N PRO 209.A O no hydrogen 2.990 N/A MET 121.A N VAL 97.A O no hydrogen 2.799 N/A ILE 122.A N ALA 211.A O no hydrogen 2.847 N/A THR 123.A N GLY 99.A O no hydrogen 3.092 N/A THR 123.A OG1 VAL 213.A O no hydrogen 2.809 N/A GLY 124.A N ASN 214.A OD1 no hydrogen 2.749 N/A THR 125.A OG1 SER 101.A O no hydrogen 2.871 N/A THR 125.A OG1 THR 123.A O no hydrogen 3.410 N/A ALA 129.A N GLU 132.A OE1 no hydrogen 2.968 N/A ARG 130.A NH1 SER 193.A O no hydrogen 2.906 N/A GLU 131.A N GLU 131.A OE1 no hydrogen 2.799 N/A GLU 132.A N ALA 129.A O no hydrogen 2.907 N/A GLN 135.A N GLU 132.A O no hydrogen 2.930 N/A GLY 136.A N GLU 132.A O no hydrogen 2.991 N/A PHE 137.A N VAL 133.A O no hydrogen 3.110 N/A LYS 138.A N PHE 220.A O no hydrogen 2.789 N/A LYS 138.A NZ.A GLU 222.A OE1 no hydrogen 2.877 N/A LYS 138.A NZ.B GLU 218.A O no hydrogen 2.830 N/A MET 143.A N GLY 140.A O no hydrogen 3.108 N/A LEU 145.A N ASP 142.A O no hydrogen 3.195 N/A ALA 146.A N MET 143.A O no hydrogen 3.290 N/A GLN 148.A N LEU 145.A O no hydrogen 3.126 N/A GLN 148.A NE2 ILE 150.A O no hydrogen 2.870 N/A SER 152.A OG ARG 154.A O no hydrogen 2.254 N/A SER 158.A OG ASP 142.A OD1 no hydrogen 2.602 N/A TYR 159.A OH ASN 32.A O no hydrogen 2.745 N/A ALA 160.A N VAL 156.A O no hydrogen 2.988 N/A ARG 161.A N GLU 157.A O no hydrogen 2.904 N/A ARG 161.A NE GLU 157.A OE2 no hydrogen 2.899 N/A ARG 161.A NH2 GLU 157.A OE2 no hydrogen 3.280 N/A SER 162.A N SER 158.A O no hydrogen 3.006 N/A SER 162.A OG SER 158.A O no hydrogen 2.985 N/A SER 162.A OG TYR 159.A O no hydrogen 3.096 N/A THR 163.A N TYR 159.A O no hydrogen 2.924 N/A THR 163.A OG1 TYR 159.A O no hydrogen 2.803 N/A CYS 164.A N ALA 160.A O no hydrogen 3.000 N/A CYS 164.A SG THR 163.A OG1 no hydrogen 3.741 N/A GLY 165.A N ARG 161.A O no hydrogen 3.046 N/A LEU 172.A N GLU 169.A O no hydrogen 2.925 N/A LEU 173.A N ALA 170.A O no hydrogen 2.860 N/A ILE 175.A N SER 171.A O no hydrogen 3.260 N/A VAL 176.A N LEU 172.A O no hydrogen 3.083 N/A ALA 177.A N LEU 173.A O no hydrogen 2.871 N/A ARG 178.A N ASP 174.A O no hydrogen 3.176 N/A ARG 178.A NE GLY 62.A O no hydrogen 2.859 N/A ARG 178.A NH1 ASP 66.A OD1 no hydrogen 2.886 N/A ARG 178.A NH1 ARG 178.A O no hydrogen 2.835 N/A ARG 178.A NH2 SER 64.A O no hydrogen 2.726 N/A ARG 178.A NH2 ASP 66.A OD1 no hydrogen 2.972 N/A THR 179.A N VAL 176.A O no hydrogen 3.303 N/A THR 179.A OG1 ILE 175.A O no hydrogen 3.420 N/A THR 179.A OG1 VAL 176.A O no hydrogen 3.254 N/A ASP 180.A N GLY 60.A O no hydrogen 2.971 N/A ARG 182.A N ASP 180.A OD1 no hydrogen 3.175 N/A ARG 182.A NE ASP 180.A OD1 no hydrogen 3.016 N/A ARG 182.A NE ASP 180.A OD2 no hydrogen 3.327 N/A ARG 182.A NH2 ASP 180.A OD2 no hydrogen 2.845 N/A ALA 183.A N ASP 180.A O no hydrogen 2.901 N/A ARG 184.A NE GLN 148.A O no hydrogen 2.791 N/A ARG 184.A NH1 SER 33.A OG no hydrogen 2.889 N/A ARG 184.A NH2 GLU 149.A O no hydrogen 2.936 N/A ARG 185.A N GLY 181.A O no hydrogen 3.285 N/A ARG 185.A NE GLU 149.A OE1 no hydrogen 2.664 N/A ARG 185.A NH2 GLU 149.A OE1 no hydrogen 3.027 N/A ILE 186.A N ARG 182.A O no hydrogen 2.948 N/A MET 187.A N ALA 183.A O no hydrogen 3.098 N/A PHE 188.A N ARG 184.A O no hydrogen 3.076 N/A GLU 189.A N ARG 185.A O no hydrogen 3.066 N/A LYS 190.A N ILE 186.A O no hydrogen 3.019 N/A PHE 191.A N MET 187.A O no hydrogen 2.963 N/A GLY 192.A N PHE 188.A O no hydrogen 3.110 N/A SER 193.A N GLU 189.A O no hydrogen 3.102 N/A SER 193.A N LYS 190.A O no hydrogen 3.270 N/A SER 193.A OG.A GLU 189.A O no hydrogen 3.201 N/A SER 193.A OG.B GLU 189.A O no hydrogen 2.932 N/A SER 193.A OG.B LYS 190.A O no hydrogen 3.000 N/A GLY 194.A N PHE 191.A O no hydrogen 3.107 N/A THR 195.A N LYS 190.A O no hydrogen 3.149 N/A THR 195.A OG1 GLU 77.A OE2 no hydrogen 2.554 N/A THR 195.A OG1 LYS 190.A O no hydrogen 3.388 N/A GLY 197.A N GLU 109.A OE1.B no hydrogen 3.357 N/A GLY 197.A N GLU 109.A OE2.A no hydrogen 2.749 N/A GLN 199.A NE2 GLU 109.A OE2.B no hydrogen 3.393 N/A ARG 200.A NE ASP 201.A OD1 no hydrogen 3.183 N/A ARG 200.A NH1 GLU 131.A OE2 no hydrogen 3.216 N/A ARG 200.A NH1 GLU 132.A OE2 no hydrogen 2.878 N/A ARG 200.A NH2 ASP 201.A OD1 no hydrogen 3.502 N/A ASP 201.A N ASN 198.A OD1 no hydrogen 3.126 N/A ILE 202.A N ASN 198.A O no hydrogen 2.927 N/A VAL 203.A N GLN 199.A O no hydrogen 3.104 N/A ALA 204.A N ARG 200.A O no hydrogen 3.176 N/A GLU 205.A N ASP 201.A O no hydrogen 3.142 N/A GLU 205.A N ILE 202.A O no hydrogen 3.316 N/A GLN 207.A NE2 GLU 205.A O no hydrogen 3.107 N/A ILE 210.A N ASN 233.A O no hydrogen 2.965 N/A ALA 211.A N LEU 120.A O no hydrogen 2.762 N/A VAL 213.A N ILE 122.A O no hydrogen 3.188 N/A ASN 214.A N HIS 240.A O no hydrogen 2.946 N/A ARG 216.A N ILE 242.A O no hydrogen 2.859 N/A ARG 216.A NE ASP 243.A OD1 no hydrogen 2.780 N/A ASP 217.A N ALA 245.A O no hydrogen 2.882 N/A GLU 218.A N GLY 215.A O no hydrogen 3.070 N/A PHE 220.A N GLU 218.A OE2 no hydrogen 2.870 N/A VAL 221.A N GLU 218.A OE2 no hydrogen 2.974 N/A GLU 222.A N GLY 136.A O no hydrogen 2.914 N/A VAL 226.A N GLU 222.A O no hydrogen 3.077 N/A SER 227.A N LEU 223.A O no hydrogen 2.926 N/A SER 227.A OG.A LEU 223.A O no hydrogen 3.544 N/A SER 227.A OG.A ASP 224.A O no hydrogen 2.863 N/A SER 227.A OG.B LEU 223.A O no hydrogen 2.726 N/A SER 227.A OG.B THR 239.A OG1 no hydrogen 3.294 N/A LYS 228.A N PHE 225.A O no hydrogen 2.900 N/A LYS 228.A NZ ASP 224.A OD1.A no hydrogen 3.283 N/A VAL 229.A N VAL 226.A O no hydrogen 3.216 N/A GLY 232.A N VAL 203.A O no hydrogen 2.910 N/A ASN 233.A ND2 GLN 207.A O no hydrogen 3.033 N/A TRP 235.A N ILE 210.A O no hydrogen 2.807 N/A TRP 235.A NE1 ASP 267.A OD2 no hydrogen 2.821 N/A GLY 237.A N LEU 234.A O no hydrogen 2.886 N/A THR 239.A OG1 SER 227.A OG.B no hydrogen 3.294 N/A HIS 240.A N VAL 212.A O no hydrogen 2.865 N/A ILE 242.A N ASN 214.A O no hydrogen 2.807 N/A GLY 246.A N GLU 252.A OE1 no hydrogen 2.813 N/A GLY 246.A N GLU 252.A OE2 no hydrogen 3.265 N/A HIS 247.A ND1 GLU 218.A OE1 no hydrogen 2.654 N/A HIS 247.A NE2 SER 101.A OG no hydrogen 2.902 N/A ALA 248.A N GLU 252.A OE1 no hydrogen 2.896 N/A ARG 251.A N ALA 248.A O no hydrogen 2.971 N/A ARG 251.A NH1 CYS 164.A O no hydrogen 2.963 N/A ARG 251.A NH1 GLY 165.A O no hydrogen 3.179 N/A ARG 251.A NH1 PRO 167.A O no hydrogen 2.931 N/A ARG 251.A NH2 PRO 167.A O no hydrogen 2.876 N/A GLU 252.A N ALA 248.A O no hydrogen 2.981 N/A ALA 253.A N PRO 249.A O no hydrogen 2.869 N/A PHE 257.A N ALA 253.A O no hydrogen 2.947 N/A ASP 258.A N PRO 254.A O no hydrogen 2.743 N/A ALA 259.A N ALA 255.A O no hydrogen 3.083 N/A TYR 260.A N GLU 256.A O no hydrogen 3.487 N/A LEU 261.A N PHE 257.A O no hydrogen 2.947 N/A ALA 262.A N ASP 258.A O no hydrogen 2.805 N/A ARG 263.A N ALA 259.A O no hydrogen 3.120 N/A ARG 263.A NE GLU 236.A OE2 no hydrogen 2.753 N/A ARG 263.A NH2 GLU 236.A OE1 no hydrogen 3.006 N/A ARG 263.A NH2 GLU 236.A OE2 no hydrogen 3.555 N/A PHE 264.A N TYR 260.A O no hydrogen 2.943 N/A ILE 265.A N LEU 261.A O no hydrogen 2.915 N/A ARG 266.A N ALA 262.A O no hydrogen 2.981 N/A ARG 266.A NE ASP 267.A OD1 no hydrogen 2.842 N/A ARG 266.A NH2 ASP 267.A OD1 no hydrogen 2.898 N/A ASP 267.A N ARG 263.A O no hydrogen 2.879 N/A CYS 268.A N PHE 264.A O no hydrogen 2.893 N/A CYS 268.A SG ARG 118.A O no hydrogen 3.424 N/A CYS 268.A SG PHE 264.A O no hydrogen 3.351 N/A THR 269.A N ARG 266.A O no hydrogen 3.289 N/A THR 269.A OG1 ILE 265.A O no hydrogen 2.682 N/A GLN 270.A N ARG 266.A O no hydrogen 2.715 N/A GLU 272.A N GLU 272.A OE1 no hydrogen 2.567 N/A