Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4gms_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): HIS 8.A ND1 HIS 9.A O no hydrogen 3.043 N/A VAL 11.A N ASN 313.A OD1 no hydrogen 2.882 N/A THR 15.A N VAL 27.A O no hydrogen 2.841 N/A VAL 17.A N ILE 25.A O no hydrogen 2.870 N/A THR 19.A N ASN 22.A O no hydrogen 2.722 N/A THR 19.A OG1 ASN 22.A O no hydrogen 3.560 N/A THR 21.A N THR 19.A OG1 no hydrogen 3.309 N/A ASN 22.A N THR 19.A O no hydrogen 3.466 N/A ILE 25.A N VAL 17.A O no hydrogen 2.933 N/A VAL 27.A N THR 15.A O no hydrogen 2.833 N/A THR 28.A N MET 311.A O no hydrogen 3.098 N/A THR 31.A N LEU 307.A O no hydrogen 2.791 N/A LEU 33.A N LEU 305.A O no hydrogen 2.994 N/A VAL 34.A N GLU 32.A OE2 no hydrogen 3.088 N/A GLN 35.A N PHE 285.A O no hydrogen 2.710 N/A GLN 35.A NE2 SER 37.A O no hydrogen 3.397 N/A SER 38.A OG SER 278.A O no hydrogen 2.815 N/A GLY 40.A N SER 38.A OG no hydrogen 3.223 N/A LYS 41.A N THR 39.A OG1 no hydrogen 3.427 N/A ILE 42.A N PRO 264.A O no hydrogen 2.893 N/A CYS 43.A N SER 278.A OG no hydrogen 2.899 N/A CYS 43.A SG SER 278.A OG no hydrogen 3.639 N/A ASN 44.A N GLY 266.A O no hydrogen 3.053 N/A ASN 45.A N CYS 268.A O no hydrogen 3.342 N/A HIS 47.A NE2 GLU 271.A O no hydrogen 3.226 N/A ARG 48.A N ASP 76.A OD2 no hydrogen 2.856 N/A LEU 50.A N LEU 77.A O no hydrogen 2.943 N/A GLY 52.A N VAL 79.A O no hydrogen 3.109 N/A ILE 53.A N ASP 51.A OD1 no hydrogen 2.830 N/A CYS 55.A N GLY 52.A O no hydrogen 2.868 N/A CYS 55.A SG HIS 66.A NE2 no hydrogen 3.925 N/A CYS 55.A SG HIS 66.A O no hydrogen 3.874 N/A LEU 57.A N GLU 80.A OE2 no hydrogen 2.881 N/A ASP 59.A N THR 56.A OG1 no hydrogen 3.300 N/A ALA 60.A N THR 56.A O no hydrogen 3.166 N/A LEU 61.A N LEU 57.A O no hydrogen 2.858 N/A LEU 62.A N ILE 58.A O no hydrogen 2.811 N/A GLY 63.A N ASP 59.A O no hydrogen 2.835 N/A ASP 64.A N ASP 59.A O no hydrogen 3.205 N/A HIS 66.A ND1 ASP 64.A OD1 no hydrogen 3.300 N/A CYS 67.A N ASP 64.A O no hydrogen 2.791 N/A ASP 68.A N PRO 65.A O no hydrogen 2.876 N/A PHE 70.A N CYS 67.A O no hydrogen 2.864 N/A GLN 71.A N ASP 68.A O no hydrogen 3.382 N/A GLN 71.A NE2 ASP 68.A OD1 no hydrogen 3.160 N/A GLN 71.A NE2 SER 140.A OG no hydrogen 3.143 N/A GLU 73.A N PHE 70.A O no hydrogen 3.171 N/A LYS 74.A N GLU 73.A OE1 no hydrogen 3.148 N/A TRP 75.A N GLY 107.A O no hydrogen 3.043 N/A TRP 75.A NE1 ALA 104.A O no hydrogen 3.207 N/A ASP 76.A N ARG 48.A O no hydrogen 2.795 N/A LEU 77.A N ARG 48.A O no hydrogen 2.974 N/A PHE 78.A N SER 257.A O no hydrogen 2.867 N/A VAL 79.A N LEU 50.A O no hydrogen 2.883 N/A GLU 80.A N MET 259.A O no hydrogen 2.860 N/A ARG 81.A NE ASP 51.A OD1 no hydrogen 2.960 N/A ARG 81.A NH1 SER 261.A O no hydrogen 2.683 N/A ARG 81.A NH1 ALA 263.A O no hydrogen 2.855 N/A ARG 81.A NH2 ASP 51.A OD2 no hydrogen 3.095 N/A ARG 81.A NH2 ALA 263.A O no hydrogen 3.165 N/A SER 82.A N ASP 262.A OD1 no hydrogen 3.204 N/A SER 82.A OG ASP 262.A OD1 no hydrogen 2.957 N/A SER 82.A OG ASP 262.A OD2 no hydrogen 2.707 N/A ALA 84.A N ARG 81.A O no hydrogen 3.461 N/A PHE 85.A N ASN 54.A O no hydrogen 3.048 N/A SER 86.A OG ASP 59.A OD1 no hydrogen 3.173 N/A SER 86.A OG ASP 59.A OD2 no hydrogen 2.787 N/A ASN 87.A N ASP 64.A OD2 no hydrogen 2.999 N/A TYR 89.A OH SER 219.A OG no hydrogen 2.772 N/A TYR 91.A OH ASP 59.A OD1 no hydrogen 2.666 N/A ASP 92.A N ILE 221.A O no hydrogen 2.839 N/A SER 98.A N ASP 95.A O no hydrogen 3.031 N/A SER 98.A OG ASP 95.A OD1 no hydrogen 2.893 N/A SER 98.A OG ASP 95.A OD2 no hydrogen 3.023 N/A LEU 99.A N ASP 95.A O no hydrogen 3.298 N/A ARG 100.A N TYR 96.A O no hydrogen 2.891 N/A ARG 100.A NE GLU 80.A OE1 no hydrogen 2.976 N/A ARG 100.A NH2 GLU 80.A OE1 no hydrogen 3.263 N/A SER 101.A N ALA 97.A O no hydrogen 2.833 N/A LEU 102.A N SER 98.A O no hydrogen 2.822 N/A VAL 103.A N LEU 99.A O no hydrogen 2.954 N/A ALA 104.A N ARG 100.A O no hydrogen 2.880 N/A SER 105.A N SER 101.A O no hydrogen 2.823 N/A SER 106.A N LEU 102.A O no hydrogen 2.887 N/A SER 106.A OG LYS 250.A O no hydrogen 3.511 N/A GLY 107.A N VAL 103.A O no hydrogen 2.973 N/A LEU 109.A N GLU 73.A O no hydrogen 2.781 N/A GLU 110.A N THR 108.A OG1 no hydrogen 3.201 N/A PHE 111.A N ASN 72.A OD1 no hydrogen 2.910 N/A ILE 112.A N TYR 248.A O no hydrogen 2.800 N/A GLU 114.A N ARG 246.A O no hydrogen 3.084 N/A THR 122.A N TYR 146.A O no hydrogen 2.697 N/A THR 122.A OG1 LYS 147.A O no hydrogen 2.782 N/A ASN 124.A N ASN 143.A OD1 no hydrogen 2.798 N/A GLY 125.A N TRP 144.A O no hydrogen 2.925 N/A SER 127.A N GLY 137.A O no hydrogen 2.780 N/A ALA 129.A N SER 127.A OG no hydrogen 2.892 N/A ARG 132.A NE ASP 68.A OD2 no hydrogen 3.159 N/A ARG 132.A NH1 PHE 138.A O no hydrogen 2.998 N/A ARG 132.A NH2 ASP 68.A OD2 no hydrogen 2.903 N/A ARG 132.A NH2 PHE 138.A O no hydrogen 3.245 N/A GLY 137.A N SER 127.A O no hydrogen 2.881 N/A SER 140.A N GLY 63.A O no hydrogen 3.057 N/A SER 140.A OG GLY 63.A O no hydrogen 3.498 N/A SER 140.A OG ASP 68.A OD1 no hydrogen 3.155 N/A ARG 141.A N LEU 62.A O no hydrogen 3.099 N/A LEU 142.A N PHE 139.A O no hydrogen 3.075 N/A ASN 143.A N ALA 244.A O no hydrogen 2.770 N/A ASN 143.A ND2 GLN 123.A OE1 no hydrogen 3.017 N/A TRP 144.A NE1 TYR 186.A OH no hydrogen 2.903 N/A TYR 146.A N THR 122.A O no hydrogen 2.965 N/A LYS 147.A N LEU 185.A O no hydrogen 2.917 N/A LYS 147.A NZ GLY 149.A O no hydrogen 2.987 N/A SER 148.A N THR 151.A O no hydrogen 3.010 N/A THR 151.A N SER 148.A O no hydrogen 3.385 N/A GLN 155.A N SER 238.A O no hydrogen 2.664 N/A GLN 155.A NE2 THR 119.A O no hydrogen 3.582 N/A VAL 157.A N ILE 236.A O no hydrogen 2.894 N/A MET 159.A N LEU 234.A O no hydrogen 2.823 N/A ASN 161.A N ASP 232.A O no hydrogen 3.144 N/A ASN 161.A ND2 SER 165.A O no hydrogen 3.116 N/A ASN 161.A ND2 VAL 228.A O no hydrogen 3.061 N/A ASP 163.A N ASN 161.A OD1 no hydrogen 2.790 N/A SER 165.A OG ASN 164.A OD1 no hydrogen 3.046 N/A LYS 167.A N VAL 228.A O no hydrogen 3.067 N/A LYS 167.A NZ GLU 114.A OE2 no hydrogen 3.059 N/A LYS 167.A NZ PRO 160.A O no hydrogen 3.115 N/A LEU 168.A N PHE 249.A O no hydrogen 2.999 N/A TYR 169.A N THR 226.A O no hydrogen 2.815 N/A TYR 169.A OH GLU 114.A OE1 no hydrogen 2.748 N/A TRP 171.A N TYR 224.A O no hydrogen 2.897 N/A GLY 172.A N ILE 243.A O no hydrogen 2.902 N/A VAL 173.A N SER 222.A O no hydrogen 2.801 N/A HIS 174.A N ASN 241.A O no hydrogen 2.843 N/A HIS 174.A NE2 TYR 89.A OH no hydrogen 3.047 N/A HIS 175.A N ARG 220.A O no hydrogen 2.765 N/A HIS 175.A NE2 SER 222.A OG no hydrogen 3.032 N/A SER 177.A N GLU 181.A OE1 no hydrogen 2.957 N/A SER 177.A OG GLU 181.A OE1 no hydrogen 2.839 N/A GLU 181.A N THR 178.A OG1 no hydrogen 3.091 N/A GLN 182.A N THR 178.A O no hydrogen 3.160 N/A GLN 182.A NE2 GLN 188.A O no hydrogen 3.005 N/A GLN 182.A NE2 ASN 241.A OD1 no hydrogen 2.751 N/A THR 183.A N ASP 179.A O no hydrogen 2.907 N/A THR 183.A OG1 ASP 179.A O no hydrogen 3.384 N/A THR 183.A OG1 LYS 180.A O no hydrogen 3.008 N/A ASN 184.A N LYS 180.A O no hydrogen 2.779 N/A LEU 185.A N GLU 181.A O no hydrogen 3.288 N/A LEU 185.A N GLN 182.A O no hydrogen 3.351 N/A TYR 186.A N GLN 182.A O no hydrogen 2.842 N/A TYR 186.A OH HIS 174.A ND1 no hydrogen 2.960 N/A VAL 187.A N THR 183.A O no hydrogen 2.884 N/A GLN 188.A NE2 TYR 152.A O no hydrogen 3.455 N/A GLN 188.A NE2 ASN 239.A O no hydrogen 2.665 N/A LYS 192.A N GLY 240.A O no hydrogen 2.968 N/A VAL 193.A N ILE 204.A O no hydrogen 2.928 N/A THR 194.A N ASN 237.A O no hydrogen 2.840 N/A THR 194.A OG1 THR 203.A OG1 no hydrogen 2.996 N/A VAL 195.A N GLN 202.A O no hydrogen 2.831 N/A SER 196.A N VAL 235.A O no hydrogen 2.834 N/A SER 196.A OG VAL 235.A O no hydrogen 3.439 N/A THR 197.A N SER 200.A O no hydrogen 2.855 N/A THR 197.A OG1 SER 200.A O no hydrogen 3.442 N/A THR 197.A OG1 SER 200.A OG no hydrogen 3.176 N/A LYS 198.A N ASP 232.A OD1 no hydrogen 2.903 N/A LYS 198.A NZ GLY 231.A O no hydrogen 2.968 N/A SER 200.A N THR 197.A OG1 no hydrogen 3.310 N/A SER 200.A OG THR 197.A OG1 no hydrogen 3.176 N/A GLN 202.A N VAL 195.A O no hydrogen 2.823 N/A THR 203.A OG1 THR 194.A OG1 no hydrogen 2.996 N/A ILE 204.A N VAL 193.A O no hydrogen 2.747 N/A ASN 207.A N HIS 175.A ND1 no hydrogen 2.929 N/A GLY 209.A N PRO 176.A O no hydrogen 3.077 N/A ARG 211.A N SER 218.A O no hydrogen 3.045 N/A ARG 211.A NH1 ASN 207.A O no hydrogen 3.381 N/A ARG 211.A NH2 ASN 207.A O no hydrogen 3.004 N/A VAL 214.A N LEU 217.A O no hydrogen 2.929 N/A ARG 215.A NE CYS 88.A O no hydrogen 2.667 N/A ARG 215.A NH2 CYS 88.A O no hydrogen 3.052 N/A LEU 217.A N VAL 214.A O no hydrogen 2.965 N/A SER 218.A OG ARG 211.A O no hydrogen 3.145 N/A SER 219.A OG TYR 89.A OH no hydrogen 2.772 N/A ARG 220.A N HIS 175.A O no hydrogen 2.902 N/A ARG 220.A NH1 PRO 212.A O no hydrogen 3.218 N/A ARG 220.A NH1 LEU 217.A O no hydrogen 3.415 N/A ARG 220.A NH1 SER 219.A O no hydrogen 3.119 N/A ARG 220.A NH2 PRO 212.A O no hydrogen 2.830 N/A ILE 221.A N PRO 90.A O no hydrogen 3.252 N/A SER 222.A N VAL 173.A O no hydrogen 2.838 N/A SER 222.A OG ASP 92.A OD1 no hydrogen 2.946 N/A SER 222.A OG HIS 175.A NE2 no hydrogen 3.032 N/A ILE 223.A N ASP 92.A O no hydrogen 2.868 N/A TYR 224.A N TRP 171.A O no hydrogen 2.790 N/A THR 226.A N TYR 169.A O no hydrogen 2.875 N/A THR 226.A OG1 GLN 202.A OE1 no hydrogen 3.194 N/A VAL 228.A N LYS 167.A O no hydrogen 2.978 N/A GLY 231.A N ASN 161.A O no hydrogen 3.047 N/A ASP 232.A N LYS 229.A O no hydrogen 2.930 N/A ILE 233.A N ASP 232.A OD1 no hydrogen 2.629 N/A LEU 234.A N MET 159.A O no hydrogen 2.911 N/A VAL 235.A N SER 196.A O no hydrogen 2.820 N/A ILE 236.A N VAL 157.A O no hydrogen 2.886 N/A ASN 237.A N THR 194.A O no hydrogen 2.847 N/A ASN 237.A ND2 ASN 156.A OD1 no hydrogen 3.350 N/A SER 238.A N GLN 155.A O no hydrogen 2.774 N/A SER 238.A OG LYS 192.A O no hydrogen 3.300 N/A ASN 239.A N LYS 192.A O no hydrogen 3.322 N/A GLY 240.A N SER 238.A OG no hydrogen 2.790 N/A ASN 241.A ND2 HIS 174.A O no hydrogen 2.878 N/A ASN 241.A ND2 GLN 182.A OE1 no hydrogen 3.048 N/A ILE 243.A N GLY 172.A O no hydrogen 2.840 N/A ALA 244.A N ASN 143.A O no hydrogen 2.833 N/A ARG 246.A NE LEU 142.A O no hydrogen 2.762 N/A ARG 246.A NH1 ASN 124.A OD1 no hydrogen 3.324 N/A ARG 246.A NH2 ASN 124.A OD1 no hydrogen 2.985 N/A ARG 246.A NH2 LEU 142.A O no hydrogen 3.081 N/A TYR 248.A N ILE 112.A O no hydrogen 2.861 N/A PHE 249.A N LEU 168.A O no hydrogen 2.977 N/A LYS 250.A N GLU 110.A O no hydrogen 2.949 N/A ARG 252.A N SER 106.A OG no hydrogen 3.044 N/A ARG 252.A NH2 GLU 110.A OE2 no hydrogen 3.563 N/A LYS 255.A NZ HIS 47.A ND1 no hydrogen 3.108 N/A SER 256.A OG TRP 75.A O no hydrogen 2.644 N/A SER 257.A N ASP 76.A O no hydrogen 2.761 N/A ILE 258.A N SER 257.A OG no hydrogen 2.741 N/A MET 259.A N PHE 78.A O no hydrogen 2.812 N/A SER 261.A N GLU 80.A O no hydrogen 3.257 N/A SER 261.A OG PRO 275.A O no hydrogen 2.920 N/A ALA 263.A N SER 261.A OG no hydrogen 2.880 N/A GLY 266.A N ILE 42.A O no hydrogen 2.982 N/A SER 269.A OG ASN 45.A O no hydrogen 3.514 N/A SER 270.A N ASN 45.A O no hydrogen 2.937 N/A SER 270.A OG CYS 272.A O no hydrogen 3.363 N/A SER 270.A OG ILE 279.A O no hydrogen 3.366 N/A CYS 272.A N SER 270.A OG no hydrogen 3.348 N/A ILE 273.A N TYR 293.A O no hydrogen 2.826 N/A THR 274.A N GLY 277.A O no hydrogen 2.874 N/A THR 274.A OG1 GLY 277.A O no hydrogen 2.783 N/A ASN 276.A N THR 274.A OG1 no hydrogen 2.968 N/A GLY 277.A N THR 274.A O no hydrogen 2.773 N/A SER 278.A N LYS 41.A O no hydrogen 2.926 N/A SER 278.A OG LYS 41.A O no hydrogen 3.453 N/A ILE 279.A N CYS 272.A O no hydrogen 3.046 N/A ASN 281.A ND2 ALA 295.A O no hydrogen 3.496 N/A LYS 283.A NZ GLN 35.A OE1 no hydrogen 3.172 N/A PHE 285.A N LEU 33.A O no hydrogen 3.068 N/A GLN 286.A N LYS 298.A O no hydrogen 2.887 N/A GLN 286.A NE2 ASN 289.A O no hydrogen 2.822 N/A ASN 287.A N GLN 35.A O no hydrogen 2.959 N/A ASN 287.A ND2 VAL 300.A O no hydrogen 3.069 N/A ASN 289.A N GLN 286.A OE1 no hydrogen 3.039 N/A ASN 289.A ND2 ASN 276.A OD1 no hydrogen 2.904 N/A ILE 291.A N ASN 289.A OD1 no hydrogen 2.734 N/A TYR 293.A N ILE 273.A O no hydrogen 2.836 N/A TYR 293.A OH LYS 255.A O no hydrogen 2.503 N/A ALA 295.A N GLU 271.A O no hydrogen 3.256 N/A CYS 296.A SG TYR 293.A O no hydrogen 3.476 N/A CYS 296.A SG GLY 294.A O no hydrogen 3.805 N/A LYS 298.A N PRO 284.A O no hydrogen 3.098 N/A VAL 300.A N GLN 286.A O no hydrogen 3.087 N/A GLN 302.A N GLN 302.A OE1 no hydrogen 2.569 N/A THR 304.A OG1 GLU 32.A OE1 no hydrogen 2.735 N/A THR 304.A OG1 GLU 32.A OE2 no hydrogen 3.248 N/A LEU 305.A N GLU 32.A OE2 no hydrogen 2.917 N/A LEU 307.A N THR 31.A O no hydrogen 2.843 N/A THR 309.A N ASN 29.A O no hydrogen 2.811 N/A ASN 313.A N GLU 26.A O no hydrogen 2.963 N/A ASN 313.A ND2 VAL 11.A O no hydrogen 3.050 N/A