Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4gt4_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 5.A N VAL 70.A O no hydrogen 3.175 N/A ALA 9.A N SER 6.A O no hydrogen 3.263 N/A VAL 10.A N LEU 7.A O no hydrogen 3.192 N/A ARG 11.A N HIS 28.A O no hydrogen 2.901 N/A MET 13.A N LYS 26.A O no hydrogen 2.820 N/A LEU 16.A N VAL 24.A O no hydrogen 2.895 N/A GLY 17.A N VAL 24.A O no hydrogen 3.312 N/A GLU 18.A N PHE 160.A O.A no hydrogen 3.446 N/A GLU 18.A N PHE 160.A O.B no hydrogen 3.377 N/A ASP 19.A N GLY 22.A O no hydrogen 2.723 N/A GLY 22.A N ASP 19.A OD2 no hydrogen 2.940 N/A LYS 23.A NZ GLU 15.A OE1 no hydrogen 3.435 N/A VAL 24.A N GLY 17.A O no hydrogen 3.229 N/A TYR 25.A N ILE 36.A O no hydrogen 2.910 N/A LYS 26.A N GLU 14.A O no hydrogen 2.861 N/A GLY 27.A N VAL 34.A O no hydrogen 2.913 N/A HIS 28.A N ARG 11.A O no hydrogen 2.926 N/A LEU 29.A N GLN 32.A O no hydrogen 2.943 N/A PHE 30.A N ALA 9.A O no hydrogen 2.759 N/A GLN 32.A N LEU 29.A O no hydrogen 3.164 N/A VAL 34.A N GLY 27.A O no hydrogen 2.898 N/A ALA 35.A N PHE 81.A O no hydrogen 2.904 N/A ILE 36.A N TYR 25.A O no hydrogen 2.876 N/A LYS 37.A N MET 79.A O no hydrogen 2.884 N/A LYS 37.A NZ LEU 157.A O no hydrogen 3.265 N/A THR 38.A N LYS 23.A O no hydrogen 3.298 N/A THR 38.A OG1 LYS 23.A O no hydrogen 2.677 N/A LEU 39.A N LEU 77.A O no hydrogen 2.895 N/A LYS 40.A N PHE 21.A O no hydrogen 2.664 N/A GLU 47.A N GLY 44.A O no hydrogen 2.750 N/A PHE 49.A N LEU 45.A O no hydrogen 2.907 N/A ARG 50.A N ARG 46.A O no hydrogen 2.886 N/A HIS 51.A N GLU 47.A O no hydrogen 2.904 N/A GLU 52.A N GLU 48.A O no hydrogen 2.900 N/A ALA 53.A N PHE 49.A O no hydrogen 2.908 N/A MET 54.A N ARG 50.A O no hydrogen 2.905 N/A LEU 55.A N HIS 51.A O no hydrogen 2.902 N/A ARG 56.A N GLU 52.A O no hydrogen 2.899 N/A ARG 56.A NE GLU 52.A OE1 no hydrogen 2.446 N/A ARG 56.A NH2 GLU 52.A OE1 no hydrogen 3.048 N/A ALA 57.A N ALA 53.A O no hydrogen 2.908 N/A ARG 58.A N LEU 55.A O no hydrogen 3.320 N/A LEU 59.A N ARG 56.A O no hydrogen 3.288 N/A GLN 60.A N TYR 128.A OH no hydrogen 2.839 N/A ASN 63.A N HIS 61.A ND1 no hydrogen 3.050 N/A ASN 63.A ND2 GLN 121.A OE1 no hydrogen 3.023 N/A ASN 63.A ND2 VAL 152.A O no hydrogen 3.039 N/A VAL 64.A N HIS 61.A O no hydrogen 3.013 N/A VAL 65.A N ILE 154.A O no hydrogen 3.057 N/A LEU 68.A N ILE 80.A O no hydrogen 2.597 N/A GLY 69.A N ILE 80.A O no hydrogen 2.944 N/A VAL 70.A N LYS 3.A O no hydrogen 3.009 N/A VAL 71.A N SER 78.A O no hydrogen 2.894 N/A THR 72.A N GLU 4.A OE1 no hydrogen 2.814 N/A LYS 73.A N GLU 4.A OE1 no hydrogen 3.187 N/A SER 78.A N VAL 71.A O no hydrogen 2.922 N/A SER 78.A OG PRO 76.A O no hydrogen 3.424 N/A MET 79.A N LYS 37.A O no hydrogen 2.896 N/A ILE 80.A N GLY 69.A O no hydrogen 2.885 N/A PHE 81.A N ALA 35.A O no hydrogen 2.906 N/A SER 82.A N CYS 66.A O no hydrogen 3.025 N/A SER 82.A OG TYR 147.A OH no hydrogen 3.359 N/A TYR 83.A N ALA 33.A O no hydrogen 2.987 N/A CYS 84.A SG GLY 87.A O no hydrogen 3.251 N/A HIS 86.A NE2 ASP 148.A OD1 no hydrogen 2.522 N/A LEU 89.A N VAL 144.A O no hydrogen 2.693 N/A HIS 90.A N THR 141.A O no hydrogen 3.301 N/A GLU 91.A N ASP 88.A OD2 no hydrogen 2.984 N/A PHE 92.A N ASP 88.A O no hydrogen 3.294 N/A LEU 93.A N LEU 89.A O no hydrogen 2.905 N/A VAL 94.A N HIS 90.A O no hydrogen 2.896 N/A MET 95.A N GLU 91.A O no hydrogen 2.917 N/A ARG 96.A N LEU 93.A O no hydrogen 3.031 N/A ARG 96.A NE SER 108.A O no hydrogen 3.006 N/A ARG 96.A NE SER 108.A OG no hydrogen 3.222 N/A ARG 96.A NH1 PHE 92.A O no hydrogen 3.116 N/A ARG 96.A NH2 SER 108.A OG no hydrogen 2.759 N/A SER 97.A N VAL 94.A O no hydrogen 3.259 N/A HIS 99.A N SER 97.A OG no hydrogen 3.348 N/A VAL 102.A N SER 100.A OG no hydrogen 3.300 N/A LYS 107.A NZ THR 105.A O no hydrogen 3.208 N/A LYS 107.A NZ THR 105.A OG1 no hydrogen 3.169 N/A GLU 111.A N ASP 114.A OD2 no hydrogen 2.850 N/A ASP 114.A N GLU 111.A O no hydrogen 2.926 N/A HIS 117.A N PRO 113.A O no hydrogen 2.910 N/A LEU 118.A N ASP 114.A O no hydrogen 2.904 N/A VAL 119.A N PHE 115.A O no hydrogen 2.933 N/A ALA 120.A N VAL 116.A O no hydrogen 2.899 N/A GLN 121.A N HIS 117.A O no hydrogen 2.922 N/A GLN 121.A NE2 HIS 117.A O no hydrogen 3.674 N/A GLN 121.A NE2 LEU 150.A O no hydrogen 2.909 N/A ILE 122.A N LEU 118.A O no hydrogen 2.936 N/A ALA 123.A N VAL 119.A O no hydrogen 2.913 N/A ALA 124.A N ALA 120.A O no hydrogen 2.902 N/A GLY 125.A N GLN 121.A O no hydrogen 2.920 N/A MET 126.A N ILE 122.A O no hydrogen 2.918 N/A GLU 127.A N ALA 123.A O no hydrogen 2.896 N/A TYR 128.A N ALA 124.A O no hydrogen 2.927 N/A TYR 128.A OH ARG 58.A O no hydrogen 3.188 N/A LEU 129.A N GLY 125.A O no hydrogen 2.912 N/A SER 130.A N MET 126.A O no hydrogen 2.899 N/A SER 130.A OG MET 126.A O no hydrogen 3.078 N/A SER 130.A OG GLU 127.A O no hydrogen 2.951 N/A SER 131.A N GLU 127.A O no hydrogen 2.907 N/A SER 131.A OG GLU 127.A O no hydrogen 2.878 N/A HIS 132.A N TYR 128.A O no hydrogen 3.173 N/A HIS 132.A N LEU 129.A O no hydrogen 3.057 N/A HIS 132.A ND1 TYR 128.A O no hydrogen 3.027 N/A HIS 133.A N SER 130.A O no hydrogen 3.090 N/A VAL 134.A N LEU 129.A O no hydrogen 2.867 N/A HIS 136.A N ASP 197.A OD2 no hydrogen 3.013 N/A HIS 136.A NE2 SER 155.A O no hydrogen 2.837 N/A ASP 138.A N HIS 136.A ND1 no hydrogen 2.980 N/A THR 141.A N GLU 207.A OE1 no hydrogen 3.172 N/A THR 141.A OG1 GLU 207.A OE2 no hydrogen 2.589 N/A ARG 142.A NE TYR 168.A OH no hydrogen 2.833 N/A ARG 142.A NH2 TYR 168.A OH no hydrogen 3.303 N/A ASN 143.A N ALA 140.A O no hydrogen 2.907 N/A ASN 143.A ND2 ASP 138.A O no hydrogen 2.650 N/A VAL 144.A N THR 141.A O no hydrogen 3.075 N/A LEU 145.A N LYS 153.A O no hydrogen 2.886 N/A VAL 146.A N GLY 87.A O no hydrogen 3.178 N/A TYR 147.A N ASN 151.A O no hydrogen 2.624 N/A TYR 147.A OH SER 82.A OG no hydrogen 3.359 N/A ASN 151.A N ASP 148.A O no hydrogen 3.186 N/A ASN 151.A ND2 PRO 62.A O no hydrogen 3.312 N/A ASN 151.A ND2 GLN 121.A OE1 no hydrogen 3.070 N/A VAL 152.A N GLN 121.A OE1 no hydrogen 3.194 N/A LYS 153.A N LEU 145.A O no hydrogen 2.927 N/A LYS 153.A NZ PRO 62.A O no hydrogen 2.831 N/A LYS 153.A NZ ASN 151.A OD1 no hydrogen 3.103 N/A ILE 154.A N ASN 63.A O no hydrogen 2.797 N/A SER 155.A N ASN 143.A O no hydrogen 2.837 N/A PHE 160.A N.A GLU 18.A O no hydrogen 3.201 N/A PHE 160.A N.B GLU 18.A O no hydrogen 3.190 N/A ARG 161.A NE LEU 16.A O no hydrogen 3.391 N/A TYR 164.A N ARG 161.A O no hydrogen 3.122 N/A TYR 164.A OH ASP 88.A OD1 no hydrogen 2.618 N/A TYR 164.A OH GLU 91.A OE2 no hydrogen 3.210 N/A ALA 165.A N GLU 162.A O no hydrogen 2.913 N/A ASP 167.A N TYR 164.A O no hydrogen 2.908 N/A TYR 168.A N ALA 165.A O no hydrogen 3.191 N/A TYR 168.A OH ASP 138.A OD2 no hydrogen 2.355 N/A TYR 169.A N LEU 177.A O no hydrogen 2.836 N/A LYS 170.A NZ ASN 174.A OD1 no hydrogen 3.225 N/A LEU 171.A N TYR 169.A O no hydrogen 2.858 N/A LEU 177.A N TYR 169.A O no hydrogen 3.064 N/A ILE 179.A N LEU 177.A O no hydrogen 2.918 N/A ARG 180.A NH1 PRO 215.A O no hydrogen 3.032 N/A ARG 180.A NH1 TYR 216.A O no hydrogen 2.855 N/A ARG 180.A NH1 TYR 219.A O no hydrogen 3.370 N/A ARG 180.A NH2 TYR 219.A O no hydrogen 2.845 N/A ARG 180.A NH2 ASN 221.A OD1 no hydrogen 3.351 N/A TRP 181.A N PRO 178.A O no hydrogen 2.982 N/A TRP 181.A NE1 GLU 207.A OE1 no hydrogen 2.559 N/A MET 182.A N ILE 179.A O no hydrogen 3.052 N/A GLU 185.A N GLU 185.A OE1 no hydrogen 2.725 N/A ILE 187.A N ALA 183.A O no hydrogen 2.831 N/A MET 188.A N PRO 184.A O no hydrogen 2.900 N/A TYR 189.A N GLU 185.A O no hydrogen 2.914 N/A GLY 190.A N ALA 186.A O no hydrogen 2.706 N/A SER 193.A N SER 196.A OG no hydrogen 2.752 N/A SER 196.A OG SER 193.A O no hydrogen 2.830 N/A ASP 197.A N SER 193.A O no hydrogen 3.003 N/A ILE 198.A N ILE 194.A O no hydrogen 2.899 N/A TRP 199.A N ASP 195.A O no hydrogen 2.953 N/A SER 200.A N SER 196.A O no hydrogen 2.899 N/A SER 200.A OG TRP 181.A O no hydrogen 2.615 N/A SER 200.A OG SER 196.A O no hydrogen 2.943 N/A TYR 201.A N ASP 197.A O no hydrogen 2.883 N/A TYR 201.A OH VAL 119.A O no hydrogen 2.597 N/A GLY 202.A N ILE 198.A O no hydrogen 2.926 N/A VAL 203.A N TRP 199.A O no hydrogen 2.954 N/A VAL 204.A N SER 200.A O no hydrogen 2.886 N/A LEU 205.A N TYR 201.A O no hydrogen 2.895 N/A TRP 206.A N GLY 202.A O no hydrogen 2.950 N/A TRP 206.A NE1 PRO 235.A O no hydrogen 2.718 N/A GLU 207.A N VAL 203.A O no hydrogen 2.891 N/A VAL 208.A N VAL 204.A O no hydrogen 2.895 N/A PHE 209.A N LEU 205.A O no hydrogen 2.937 N/A SER 210.A N GLU 207.A O no hydrogen 2.980 N/A SER 210.A OG TRP 206.A O no hydrogen 2.730 N/A TYR 211.A N VAL 208.A O no hydrogen 3.301 N/A GLY 212.A N GLU 207.A O no hydrogen 2.791 N/A LEU 213.A N SER 210.A O no hydrogen 3.371 N/A GLN 214.A NE2 ALA 166.A O no hydrogen 3.361 N/A GLN 214.A NE2 ASP 167.A OD1 no hydrogen 2.862 N/A TYR 216.A OH GLN 232.A O no hydrogen 2.730 N/A TYR 219.A N TYR 216.A O no hydrogen 3.004 N/A ASP 223.A N SER 220.A OG no hydrogen 3.423 N/A VAL 224.A N SER 220.A O no hydrogen 2.854 N/A VAL 225.A N ASN 221.A O no hydrogen 2.909 N/A GLU 226.A N GLN 222.A O no hydrogen 2.922 N/A MET 227.A N ASP 223.A O no hydrogen 2.889 N/A ILE 228.A N VAL 224.A O no hydrogen 2.912 N/A ARG 229.A N VAL 225.A O no hydrogen 2.905 N/A ASN 230.A N GLU 226.A O no hydrogen 2.872 N/A ARG 231.A N ILE 228.A O no hydrogen 3.102 N/A GLN 232.A N MET 227.A O no hydrogen 2.624 N/A CYS 236.A SG PRO 237.A O no hydrogen 3.574 N/A CYS 236.A SG CYS 240.A O no hydrogen 4.019 N/A CYS 240.A N PRO 237.A O no hydrogen 3.231 N/A CYS 240.A SG PRO 241.A O no hydrogen 3.565 N/A VAL 244.A N PRO 241.A O no hydrogen 3.200 N/A TYR 245.A N PRO 241.A O no hydrogen 3.316 N/A TYR 245.A OH LEU 234.A O no hydrogen 2.726 N/A ALA 246.A N ALA 242.A O no hydrogen 2.908 N/A LEU 247.A N TRP 243.A O no hydrogen 2.913 N/A MET 248.A N VAL 244.A O no hydrogen 2.914 N/A ILE 249.A N TYR 245.A O no hydrogen 2.902 N/A GLU 250.A N ALA 246.A O no hydrogen 2.913 N/A CYS 251.A N LEU 247.A O no hydrogen 2.913 N/A CYS 251.A SG LEU 247.A O no hydrogen 3.324 N/A TRP 252.A N MET 248.A O no hydrogen 2.908 N/A TRP 252.A N ILE 249.A O no hydrogen 3.062 N/A PHE 255.A N ASN 253.A OD1 no hydrogen 2.729 N/A ARG 258.A N PHE 255.A O no hydrogen 3.095 N/A ARG 259.A N PRO 256.A O no hydrogen 3.410 N/A ARG 259.A NE ASN 253.A O no hydrogen 2.782 N/A ARG 259.A NH1 GLU 185.A OE2 no hydrogen 2.796 N/A ARG 259.A NH2 GLU 185.A OE1 no hydrogen 2.914 N/A ARG 259.A NH2 GLU 185.A OE2 no hydrogen 3.273 N/A ARG 259.A NH2 ASN 253.A O no hydrogen 3.127 N/A ARG 261.A NH1 ASP 195.A OD2 no hydrogen 3.056 N/A ARG 261.A NH1 ARG 259.A O no hydrogen 3.000 N/A ARG 261.A NH2 ASP 195.A OD2 no hydrogen 2.582 N/A ILE 265.A N ARG 261.A O no hydrogen 2.950 N/A HIS 266.A N PHE 262.A O no hydrogen 2.896 N/A HIS 266.A ND1 GLU 127.A OE1 no hydrogen 2.963 N/A SER 267.A N LYS 263.A O no hydrogen 2.922 N/A SER 267.A OG LYS 263.A O no hydrogen 3.065 N/A ARG 268.A N ASP 264.A O no hydrogen 2.899 N/A ARG 268.A NH1 GLU 250.A OE2 no hydrogen 3.096 N/A ARG 268.A NH2 GLU 250.A OE1 no hydrogen 2.536 N/A LEU 269.A N ILE 265.A O no hydrogen 2.902 N/A ARG 270.A N HIS 266.A O no hydrogen 2.905 N/A ALA 271.A N SER 267.A O no hydrogen 3.262 N/A TRP 272.A N LEU 269.A O no hydrogen 3.305 N/A