Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4gx5_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 5.A N GLN 1.A O no hydrogen 3.137 N/A LEU 6.A N ASN 2.A O no hydrogen 3.292 N/A LEU 7.A N LEU 3.A O no hydrogen 3.139 N/A LEU 8.A N LYS 4.A O no hydrogen 2.882 N/A TYR 9.A N VAL 5.A O no hydrogen 3.396 N/A TYR 9.A OH PHE 78.A O no hydrogen 2.369 N/A CYS 10.A N LEU 6.A O no hydrogen 3.046 N/A ALA 11.A N LEU 7.A O no hydrogen 3.140 N/A PHE 12.A N LEU 8.A O no hydrogen 3.229 N/A LEU 13.A N TYR 9.A O no hydrogen 3.117 N/A LEU 14.A N CYS 10.A O no hydrogen 2.993 N/A VAL 15.A N ALA 11.A O no hydrogen 3.056 N/A MET 16.A N PHE 12.A O no hydrogen 2.837 N/A LEU 17.A N LEU 13.A O no hydrogen 2.815 N/A LEU 18.A N LEU 14.A O no hydrogen 2.955 N/A ALA 19.A N VAL 15.A O no hydrogen 2.894 N/A TYR 20.A N MET 16.A O no hydrogen 2.996 N/A TYR 20.A OH SER 74.A OG no hydrogen 2.685 N/A ALA 21.A N LEU 17.A O no hydrogen 2.900 N/A SER 22.A N ALA 19.A O no hydrogen 2.929 N/A SER 22.A OG LEU 18.A O no hydrogen 3.174 N/A ILE 23.A N ALA 19.A O no hydrogen 2.874 N/A PHE 24.A N TYR 20.A O no hydrogen 2.782 N/A ARG 25.A NE TYR 36.A O no hydrogen 2.657 N/A ARG 25.A NH2 TYR 36.A O no hydrogen 3.148 N/A TYR 26.A N SER 22.A O no hydrogen 2.922 N/A LEU 27.A N ILE 23.A O no hydrogen 2.868 N/A MET 28.A N PHE 24.A O no hydrogen 2.881 N/A TRP 29.A N ARG 25.A O no hydrogen 3.425 N/A HIS 30.A N TYR 26.A O no hydrogen 2.681 N/A LEU 31.A N LEU 27.A O no hydrogen 2.452 N/A GLU 32.A N MET 28.A O no hydrogen 3.291 N/A ARG 34.A N MET 28.A O no hydrogen 2.730 N/A ARG 34.A NH1 TYR 36.A OH no hydrogen 3.229 N/A ARG 34.A NH1 THR 58.A O no hydrogen 2.868 N/A ARG 34.A NH2 THR 58.A O no hydrogen 2.894 N/A ALA 40.A N SER 37.A OG no hydrogen 3.185 N/A GLY 41.A N SER 37.A O no hydrogen 3.230 N/A ILE 42.A N PHE 38.A O no hydrogen 3.076 N/A TYR 43.A N MET 39.A O no hydrogen 2.740 N/A TYR 43.A OH ASP 56.A OD2 no hydrogen 2.996 N/A TRP 44.A N ALA 40.A O no hydrogen 2.704 N/A THR 45.A N GLY 41.A O no hydrogen 2.914 N/A THR 45.A OG1 GLY 41.A O no hydrogen 2.672 N/A ILE 46.A N ILE 42.A O no hydrogen 2.714 N/A THR 47.A N TYR 43.A O no hydrogen 3.059 N/A THR 47.A OG1 TYR 43.A O no hydrogen 3.114 N/A VAL 48.A N TRP 44.A O no hydrogen 2.815 N/A MET 49.A N THR 45.A O no hydrogen 3.073 N/A THR 50.A N ILE 46.A O no hydrogen 2.953 N/A THR 51.A N VAL 48.A O no hydrogen 2.888 N/A THR 51.A OG1 THR 50.A O no hydrogen 2.770 N/A GLY 53.A N THR 47.A O no hydrogen 3.101 N/A ILE 57.A N ASP 56.A OD1 no hydrogen 2.811 N/A GLU 60.A N GLU 32.A OE1 no hydrogen 2.557 N/A SER 61.A N GLU 32.A OE1 no hydrogen 2.668 N/A SER 61.A OG GLU 32.A OE1 no hydrogen 2.932 N/A GLY 64.A N SER 61.A OG no hydrogen 3.221 N/A TYR 65.A N SER 61.A O no hydrogen 2.967 N/A LEU 66.A N ASP 62.A O no hydrogen 2.940 N/A PHE 67.A N ALA 63.A O no hydrogen 3.154 N/A ALA 68.A N GLY 64.A O no hydrogen 3.040 N/A SER 69.A N TYR 65.A O no hydrogen 2.796 N/A SER 69.A OG TYR 65.A O no hydrogen 2.830 N/A ILE 70.A N LEU 66.A O no hydrogen 2.837 N/A VAL 71.A N PHE 67.A O no hydrogen 2.950 N/A THR 72.A N ALA 68.A O no hydrogen 2.827 N/A THR 72.A OG1 ALA 68.A O no hydrogen 3.328 N/A VAL 73.A N SER 69.A O no hydrogen 3.111 N/A SER 74.A N ILE 70.A O no hydrogen 3.002 N/A SER 74.A OG TYR 20.A OH no hydrogen 2.685 N/A SER 74.A OG ILE 70.A O no hydrogen 3.087 N/A GLY 75.A N VAL 71.A O no hydrogen 3.149 N/A GLY 75.A N THR 72.A O no hydrogen 3.060 N/A VAL 76.A N THR 72.A O no hydrogen 3.204 N/A ILE 77.A N VAL 73.A O no hydrogen 2.716 N/A PHE 78.A N SER 74.A O no hydrogen 3.265 N/A LEU 79.A N GLY 75.A O no hydrogen 2.851 N/A ILE 82.A N ILE 77.A O no hydrogen 3.423 N/A PHE 85.A N ILE 81.A O no hydrogen 2.993 N/A GLY 86.A N ILE 82.A O no hydrogen 2.528 N/A PHE 87.A N LEU 83.A O no hydrogen 3.173 N/A VAL 88.A N PRO 84.A O no hydrogen 3.003 N/A SER 89.A N PHE 85.A O no hydrogen 2.476 N/A MET 90.A N GLY 86.A O no hydrogen 3.176 N/A LEU 92.A N VAL 88.A O no hydrogen 2.585 N/A ILE 96.A N LEU 92.A O no hydrogen 3.336 N/A ILE 96.A N ALA 93.A O no hydrogen 3.165 N/A LEU 100.A N ILE 96.A O no hydrogen 2.637 N/A ARG 101.A N GLU 97.A O no hydrogen 3.258 N/A TYR 102.A OH GLU 153.A OE2 no hydrogen 2.426 N/A LEU 108.A N GLY 173.A O no hydrogen 2.923 N/A GLY 114.A N ALA 178.A O no hydrogen 3.093 N/A HIS 115.A NE2 LEU 174.A O no hydrogen 3.003 N/A ILE 116.A N LEU 138.A O no hydrogen 2.917 N/A LEU 117.A N SER 181.A O no hydrogen 2.968 N/A ILE 118.A N VAL 140.A O no hydrogen 2.754 N/A PHE 119.A N ILE 183.A O no hydrogen 2.860 N/A ASP 122.A N THR 125.A OG1 no hydrogen 2.904 N/A ILE 124.A N ASP 122.A OD1 no hydrogen 2.718 N/A THR 125.A OG1 ASP 122.A O no hydrogen 2.991 N/A ARG 126.A N ASP 122.A O no hydrogen 2.847 N/A ARG 126.A NH1 GLN 155.A OE1 no hydrogen 3.066 N/A ARG 126.A NH2 GLN 155.A OE1 no hydrogen 3.195 N/A THR 127.A N PRO 123.A O no hydrogen 3.159 N/A THR 127.A N ILE 124.A O no hydrogen 2.971 N/A THR 127.A OG1 PRO 123.A O no hydrogen 2.660 N/A THR 127.A OG1 GLU 343.A OE2 no hydrogen 3.488 N/A LEU 128.A N ILE 124.A O no hydrogen 2.770 N/A ILE 129.A N THR 125.A O no hydrogen 2.873 N/A ARG 130.A N ARG 126.A O no hydrogen 3.311 N/A LYS 131.A N THR 127.A O no hydrogen 3.204 N/A LEU 132.A N LEU 128.A O no hydrogen 3.171 N/A SER 134.A OG LYS 131.A O no hydrogen 2.460 N/A VAL 140.A N ILE 116.A O no hydrogen 3.370 N/A VAL 141.A N LYS 159.A O no hydrogen 3.112 N/A VAL 142.A N ILE 118.A O no hydrogen 3.013 N/A THR 143.A N VAL 161.A O no hydrogen 3.024 N/A THR 143.A OG1 GLN 148.A OE1 no hydrogen 2.715 N/A ASN 145.A N THR 143.A OG1 no hydrogen 2.886 N/A GLN 148.A N ASN 145.A O no hydrogen 3.208 N/A ALA 149.A N ASN 145.A O no hydrogen 3.065 N/A LEU 150.A N TYR 146.A O no hydrogen 3.221 N/A LEU 152.A N GLN 148.A O no hydrogen 3.204 N/A GLU 153.A N ALA 149.A O no hydrogen 3.072 N/A GLU 153.A N LEU 150.A O no hydrogen 3.194 N/A GLU 154.A N LEU 150.A O no hydrogen 3.248 N/A GLN 155.A N HIS 151.A O no hydrogen 3.295 N/A GLN 155.A NE2 GLN 155.A O no hydrogen 2.369 N/A VAL 161.A N VAL 141.A O no hydrogen 2.886 N/A TYR 162.A N THR 105.A O no hydrogen 2.999 N/A GLY 163.A N THR 143.A O no hydrogen 2.747 N/A SER 164.A OG THR 166.A OG1 no hydrogen 3.185 N/A THR 166.A OG1 SER 164.A OG no hydrogen 3.185 N/A HIS 169.A N ASP 167.A OD1 no hydrogen 2.986 N/A LEU 171.A N ASP 167.A O no hydrogen 3.192 N/A ALA 172.A N ALA 168.A O no hydrogen 2.859 N/A GLY 173.A N HIS 169.A O no hydrogen 3.239 N/A GLY 173.A N VAL 170.A O no hydrogen 3.089 N/A LEU 174.A N VAL 170.A O no hydrogen 3.194 N/A ARG 175.A N ALA 172.A O no hydrogen 3.291 N/A ARG 175.A NE LEU 108.A O no hydrogen 3.307 N/A ARG 175.A NE PRO 109.A O no hydrogen 3.070 N/A ARG 175.A NH1 LEU 108.A O no hydrogen 3.333 N/A ALA 178.A N ARG 175.A O no hydrogen 3.026 N/A ALA 179.A N VAL 176.A O no hydrogen 3.213 N/A ARG 180.A N HIS 115.A O no hydrogen 2.874 N/A ILE 182.A N PRO 205.A O no hydrogen 2.827 N/A ILE 183.A N LEU 117.A O no hydrogen 2.733 N/A ALA 184.A N ILE 207.A O no hydrogen 3.044 N/A ASN 185.A N PHE 119.A O no hydrogen 2.783 N/A ASN 185.A ND2 GLY 120.A O no hydrogen 3.123 N/A LEU 186.A N ASN 191.A OD1 no hydrogen 2.967 N/A ASP 190.A N SER 187.A OG no hydrogen 3.150 N/A ASN 191.A N SER 187.A O no hydrogen 2.657 N/A ASN 191.A ND2 VAL 209.A O no hydrogen 3.254 N/A ALA 192.A N ASP 188.A O no hydrogen 2.868 N/A ASN 193.A N PRO 189.A O no hydrogen 3.040 N/A LEU 194.A N ASP 190.A O no hydrogen 2.654 N/A CYS 195.A N ASN 191.A O no hydrogen 2.966 N/A CYS 195.A SG ASN 191.A O no hydrogen 3.369 N/A LEU 196.A N ALA 192.A O no hydrogen 3.069 N/A THR 197.A N ASN 193.A O no hydrogen 3.095 N/A THR 197.A OG1 THR 166.A O no hydrogen 3.568 N/A THR 197.A OG1 ASN 193.A O no hydrogen 2.592 N/A THR 197.A OG1 ASN 193.A OD1 no hydrogen 3.125 N/A VAL 198.A N LEU 194.A O no hydrogen 3.012 N/A ARG 199.A N CYS 195.A O no hydrogen 2.803 N/A ARG 199.A NH1 THR 204.A O no hydrogen 2.817 N/A ARG 199.A NH2 THR 204.A O no hydrogen 3.277 N/A SER 200.A N THR 197.A O no hydrogen 3.175 N/A SER 200.A OG THR 197.A O no hydrogen 2.414 N/A LEU 201.A N VAL 198.A O no hydrogen 2.940 N/A CYS 202.A N VAL 198.A O no hydrogen 2.797 N/A CYS 202.A SG VAL 176.A O no hydrogen 3.597 N/A CYS 202.A SG VAL 198.A O no hydrogen 3.629 N/A CYS 202.A SG THR 204.A OG1 no hydrogen 3.457 N/A GLN 203.A NE2 ARG 199.A O no hydrogen 3.509 N/A THR 204.A OG1 VAL 176.A O no hydrogen 2.697 N/A ILE 206.A N ASN 225.A OD1 no hydrogen 2.639 N/A ILE 207.A N ILE 182.A O no hydrogen 2.762 N/A ALA 208.A N GLN 226.A O no hydrogen 3.087 N/A VAL 209.A N ALA 184.A O no hydrogen 2.965 N/A VAL 210.A N VAL 228.A O no hydrogen 2.984 N/A LYS 211.A N ASP 188.A OD2 no hydrogen 3.162 N/A LYS 211.A NZ ASN 185.A OD1 no hydrogen 2.823 N/A GLU 212.A N ASP 188.A OD1 no hydrogen 3.356 N/A HIS 215.A N GLU 212.A O no hydrogen 2.772 N/A HIS 215.A ND1 ASP 188.A OD1 no hydrogen 2.595 N/A GLY 216.A N PRO 213.A O no hydrogen 3.258 N/A LEU 219.A N HIS 215.A O no hydrogen 3.277 N/A LEU 219.A N GLY 216.A O no hydrogen 3.344 N/A ARG 220.A N GLY 216.A O no hydrogen 3.409 N/A LEU 221.A N GLU 217.A O no hydrogen 3.104 N/A GLY 223.A N ARG 220.A O no hydrogen 3.081 N/A ALA 224.A N LEU 219.A O no hydrogen 3.036 N/A ASN 225.A N ILE 206.A O no hydrogen 2.924 N/A GLN 226.A N ILE 206.A O no hydrogen 3.435 N/A VAL 228.A N ALA 208.A O no hydrogen 2.931 N/A LEU 230.A N VAL 228.A O no hydrogen 2.977 N/A THR 231.A OG1 LYS 211.A O no hydrogen 2.959 N/A ILE 233.A N PRO 229.A O no hydrogen 3.208 N/A LEU 234.A N LEU 230.A O no hydrogen 3.036 N/A GLY 235.A N THR 231.A O no hydrogen 3.223 N/A ARG 236.A N ARG 232.A O no hydrogen 3.086 N/A TYR 237.A N ILE 233.A O no hydrogen 2.963 N/A LEU 238.A N LEU 234.A O no hydrogen 3.161 N/A LEU 238.A N GLY 235.A O no hydrogen 3.207 N/A GLY 239.A N GLY 235.A O no hydrogen 2.982 N/A ILE 240.A N ARG 236.A O no hydrogen 2.938 N/A THR 243.A OG1 GLY 239.A O no hydrogen 3.362 N/A THR 243.A OG1 ILE 240.A O no hydrogen 3.189 N/A THR 244.A N ILE 240.A O no hydrogen 3.081 N/A GLU 247.A N GLU 245.A OE1 no hydrogen 2.466 N/A LEU 248.A N SER 308.A OG no hydrogen 3.348 N/A ILE 249.A N PRO 271.A O no hydrogen 3.098 N/A PHE 250.A N GLY 309.A O no hydrogen 2.631 N/A ILE 251.A N ILE 273.A O no hydrogen 2.832 N/A ILE 252.A N ILE 311.A O no hydrogen 2.791 N/A GLY 253.A N ILE 275.A O no hydrogen 2.898 N/A HIS 254.A N ASP 276.A OD1 no hydrogen 2.507 N/A ARG 256.A NE GLU 212.A OE1 no hydrogen 3.028 N/A ARG 256.A NH2 GLU 212.A OE1 no hydrogen 2.966 N/A CYS 259.A N GLY 255.A O no hydrogen 3.328 N/A ALA 260.A N ARG 256.A O no hydrogen 2.937 N/A ALA 261.A N ILE 257.A O no hydrogen 2.625 N/A ALA 262.A N GLY 258.A O no hydrogen 2.957 N/A ALA 263.A N CYS 259.A O no hydrogen 2.855 N/A PHE 264.A N ALA 260.A O no hydrogen 2.866 N/A LEU 265.A N ALA 261.A O no hydrogen 2.910 N/A ARG 267.A N ALA 263.A O no hydrogen 3.231 N/A LYS 268.A N PHE 264.A O no hydrogen 3.454 N/A VAL 270.A N LEU 265.A O no hydrogen 2.902 N/A ILE 273.A N ILE 249.A O no hydrogen 3.003 N/A ILE 275.A N ILE 251.A O no hydrogen 3.022 N/A ASP 276.A N VAL 289.A O no hydrogen 3.086 N/A ARG 277.A N ASP 276.A OD2 no hydrogen 2.812 N/A CYS 283.A SG HIS 286.A ND1 no hydrogen 3.649 N/A VAL 289.A N LEU 274.A O no hydrogen 2.673 N/A GLY 291.A N ASP 276.A O no hydrogen 2.778 N/A THR 294.A N ASP 292.A OD1 no hydrogen 3.208 N/A THR 298.A OG1 ASP 292.A O no hydrogen 2.636 N/A THR 298.A OG1 VAL 295.A O no hydrogen 2.731 N/A ARG 300.A NH2 GLN 297.A OE1 no hydrogen 2.329 N/A GLN 301.A N GLN 297.A O no hydrogen 2.878 N/A GLY 303.A N ARG 300.A O no hydrogen 3.001 N/A ILE 304.A N LEU 299.A O no hydrogen 3.080 N/A SER 308.A N LEU 248.A O no hydrogen 2.646 N/A ILE 310.A N ARG 335.A O no hydrogen 2.998 N/A ILE 311.A N PHE 250.A O no hydrogen 2.581 N/A VAL 312.A N VAL 337.A O no hydrogen 2.780 N/A THR 313.A N ILE 252.A O no hydrogen 2.682 N/A THR 314.A N ASN 320.A OD1 no hydrogen 2.927 N/A THR 314.A OG1 ASN 320.A OD1 no hydrogen 2.971 N/A THR 319.A N ASP 316.A O no hydrogen 3.263 N/A THR 319.A OG1 ASP 316.A OD1 no hydrogen 2.818 N/A ASN 320.A N ASP 316.A O no hydrogen 3.020 N/A ASN 320.A ND2 THR 314.A O no hydrogen 2.959 N/A ASN 320.A ND2 ARG 339.A O no hydrogen 2.802 N/A ILE 321.A N ASP 317.A O no hydrogen 2.803 N/A PHE 322.A N SER 318.A O no hydrogen 3.245 N/A LEU 323.A N THR 319.A O no hydrogen 2.874 N/A LEU 323.A N ASN 320.A O no hydrogen 3.128 N/A THR 324.A N ASN 320.A O no hydrogen 2.859 N/A THR 324.A OG1 ASN 320.A O no hydrogen 2.719 N/A LEU 325.A N ILE 321.A O no hydrogen 2.711 N/A ALA 326.A N PHE 322.A O no hydrogen 3.228 N/A CYS 327.A N LEU 323.A O no hydrogen 2.550 N/A CYS 327.A SG LEU 323.A O no hydrogen 3.290 N/A ARG 328.A N THR 324.A O no hydrogen 3.065 N/A ARG 328.A NH1 ASP 355.A OD2 no hydrogen 3.365 N/A HIS 329.A N LEU 325.A O no hydrogen 3.401 N/A LEU 330.A N ALA 326.A O no hydrogen 3.174 N/A ARG 335.A NH1 ARG 241.A O no hydrogen 2.492 N/A ILE 336.A N ASP 355.A OD2 no hydrogen 3.343 N/A VAL 337.A N ILE 310.A O no hydrogen 2.910 N/A ALA 338.A N PHE 356.A O no hydrogen 3.186 N/A ARG 339.A NE ASN 341.A OD1 no hydrogen 2.849 N/A ARG 339.A NH2 ASN 341.A OD1 no hydrogen 2.793 N/A ALA 340.A N VAL 358.A O no hydrogen 2.954 N/A ASN 341.A N ASP 317.A OD2 no hydrogen 2.898 N/A GLY 342.A N ASP 317.A OD1 no hydrogen 2.974 N/A GLU 344.A N GLU 344.A OE1 no hydrogen 2.880 N/A ASN 345.A N GLY 342.A O no hydrogen 3.292 N/A ASN 345.A ND2 ASP 317.A OD1 no hydrogen 3.365 N/A GLN 348.A N ASN 345.A O no hydrogen 3.183 N/A LEU 349.A N ASN 345.A O no hydrogen 3.258 N/A LEU 349.A N VAL 346.A O no hydrogen 3.226 N/A TYR 350.A N VAL 346.A O no hydrogen 3.359 N/A ALA 351.A N ASP 347.A O no hydrogen 3.036 N/A ALA 352.A N LEU 349.A O no hydrogen 3.282 N/A GLY 353.A N LEU 349.A O no hydrogen 3.071 N/A ALA 354.A N LEU 349.A O no hydrogen 2.810 N/A ASP 355.A N ILE 336.A O no hydrogen 2.754 N/A VAL 357.A N TYR 350.A OH no hydrogen 3.148 N/A VAL 358.A N ALA 338.A O no hydrogen 3.066 N/A SER 359.A OG SER 362.A OG no hydrogen 2.809 N/A ASN 360.A N ALA 340.A O no hydrogen 2.650 N/A ALA 361.A N ASN 341.A O no hydrogen 3.324 N/A SER 362.A OG GLU 343.A OE1 no hydrogen 2.882 N/A SER 362.A OG SER 359.A OG no hydrogen 2.809 N/A VAL 363.A N SER 359.A O no hydrogen 3.097 N/A GLY 364.A N ASN 360.A O no hydrogen 2.866 N/A ALA 365.A N ALA 361.A O no hydrogen 2.969 N/A ASN 366.A N SER 362.A O no hydrogen 3.120 N/A ASN 366.A ND2 SER 362.A O no hydrogen 2.837 N/A ILE 367.A N VAL 363.A O no hydrogen 3.367 N/A ILE 367.A N GLY 364.A O no hydrogen 3.061 N/A LEU 368.A N GLY 364.A O no hydrogen 3.112 N/A GLY 369.A N ALA 365.A O no hydrogen 2.650 N/A ASN 370.A N ASN 366.A O no hydrogen 3.138 N/A LEU 371.A N ILE 367.A O no hydrogen 2.878 N/A LEU 372.A N GLY 369.A O no hydrogen 3.062 N/A GLU 373.A N GLY 369.A O no hydrogen 3.152 N/A HIS 374.A N ASN 370.A O no hydrogen 2.951 N/A LYS 375.A NZ LEU 372.A O no hydrogen 2.993 N/A