Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4h0u_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 5.A OG1 ASP 9.A OD1 no hydrogen 3.089 N/A TYR 7.A OH MET 169.A O no hydrogen 2.383 N/A ASP 9.A N THR 5.A O no hydrogen 2.702 N/A LEU 10.A N PRO 6.A O no hydrogen 2.932 N/A LEU 11.A N TYR 7.A O no hydrogen 2.964 N/A ARG 12.A N GLU 8.A O no hydrogen 2.780 N/A ARG 12.A NH2 LEU 219.A O no hydrogen 2.941 N/A LYS 13.A N ASP 9.A O no hydrogen 2.896 N/A ILE 14.A N LEU 10.A O no hydrogen 2.778 N/A ALA 15.A N LEU 11.A O no hydrogen 2.964 N/A GLU 16.A N ARG 12.A O no hydrogen 2.801 N/A GLU 17.A N LYS 13.A O no hydrogen 2.757 N/A GLY 18.A N ILE 14.A O no hydrogen 2.752 N/A SER 19.A N SER 27.A O no hydrogen 2.728 N/A THR 26.A N ILE 207.A O no hydrogen 2.904 N/A THR 26.A OG1 ILE 14.A O no hydrogen 3.467 N/A SER 27.A N SER 19.A O no hydrogen 2.972 N/A LEU 28.A N CYS 205.A O no hydrogen 2.905 N/A GLY 30.A N GLY 203.A O no hydrogen 2.960 N/A GLN 31.A N GLY 202.A O no hydrogen 3.118 N/A GLN 32.A NE2 THR 201.A OG1 no hydrogen 2.727 N/A ILE 33.A N TRP 200.A O no hydrogen 2.743 N/A PHE 35.A N PHE 198.A O no hydrogen 2.892 N/A LEU 37.A N GLY 196.A O no hydrogen 3.113 N/A ASN 38.A N ASP 36.A OD1 no hydrogen 3.030 N/A GLU 39.A N ASP 36.A O no hydrogen 2.976 N/A GLY 40.A N LEU 37.A O no hydrogen 3.232 N/A PHE 41.A N PRO 227.A O no hydrogen 2.904 N/A LEU 43.A N PHE 41.A O no hydrogen 2.502 N/A THR 45.A OG1 ARG 224.A O no hydrogen 2.902 N/A THR 46.A OG1 GLU 8.A OE1 no hydrogen 2.638 N/A THR 46.A OG1 GLU 8.A OE2 no hydrogen 2.943 N/A LYS 47.A NZ PHE 170.A O no hydrogen 2.808 N/A VAL 49.A N TYR 250.A OH no hydrogen 3.052 N/A VAL 55.A N PHE 51.A O no hydrogen 2.866 N/A GLY 56.A N HIS 52.A O no hydrogen 2.900 N/A GLU 57.A N SER 53.A O no hydrogen 2.952 N/A LEU 58.A N VAL 54.A O no hydrogen 3.182 N/A LEU 59.A N VAL 55.A O no hydrogen 3.212 N/A TRP 60.A N GLY 56.A O no hydrogen 3.115 N/A TRP 60.A NE1 ASN 67.A O no hydrogen 2.933 N/A PHE 61.A N GLU 57.A O no hydrogen 2.824 N/A LEU 62.A N LEU 58.A O no hydrogen 2.936 N/A GLN 63.A N LEU 59.A O no hydrogen 2.990 N/A GLN 63.A N TRP 60.A O no hydrogen 3.258 N/A GLY 64.A N TRP 60.A O no hydrogen 3.301 N/A GLY 64.A N PHE 61.A O no hydrogen 2.813 N/A SER 66.A OG GLU 88.A OE2 no hydrogen 2.844 N/A ASN 67.A N ASP 65.A OD2 no hydrogen 2.912 N/A ASN 67.A ND2 ASP 86.A O no hydrogen 2.814 N/A ASN 67.A ND2 GLU 88.A OE1 no hydrogen 3.178 N/A ASN 67.A ND2 GLU 88.A OE2 no hydrogen 3.302 N/A VAL 68.A N GLY 87.A O no hydrogen 2.881 N/A LYS 69.A N ASN 67.A OD1 no hydrogen 3.065 N/A LYS 69.A NZ ASP 73.A OD2 no hydrogen 2.585 N/A LEU 71.A N VAL 68.A O no hydrogen 3.019 N/A GLN 72.A N VAL 68.A O no hydrogen 3.162 N/A GLN 72.A NE2 ASN 80.A OD1 no hydrogen 3.033 N/A ASP 73.A N LYS 69.A O no hydrogen 2.745 N/A ASN 74.A N LEU 71.A O no hydrogen 3.279 N/A ASN 75.A N GLN 72.A O no hydrogen 2.976 N/A ILE 76.A N LEU 71.A O no hydrogen 2.708 N/A ARG 77.A NH1 ASN 75.A OD1 no hydrogen 2.926 N/A TRP 79.A NE1 GLU 57.A OE2 no hydrogen 2.708 N/A ASN 80.A N ARG 77.A O no hydrogen 2.799 N/A TRP 82.A N TRP 79.A O no hydrogen 3.054 N/A ALA 83.A N ASN 80.A O no hydrogen 3.443 N/A ASP 84.A N GLU 88.A O no hydrogen 3.217 N/A ASP 86.A N ASP 84.A OD2 no hydrogen 2.733 N/A GLY 87.A N ASP 84.A O no hydrogen 2.973 N/A GLU 88.A N ASP 84.A OD2 no hydrogen 3.231 N/A VAL 92.A N GLY 90.A O no hydrogen 2.789 N/A VAL 95.A N VAL 92.A O no hydrogen 2.750 N/A GLN 96.A NE2 ASN 133.A OD1 no hydrogen 2.798 N/A TRP 97.A N TYR 93.A O no hydrogen 3.124 N/A ARG 98.A N GLY 94.A O no hydrogen 3.282 N/A ARG 98.A NE ASP 109.A OD1 no hydrogen 3.094 N/A ARG 98.A NE ASP 109.A OD2 no hydrogen 3.417 N/A ARG 98.A NH1 ASP 109.A OD2 no hydrogen 2.898 N/A ARG 98.A NH2 LEU 62.A O no hydrogen 2.690 N/A SER 99.A OG VAL 95.A O no hydrogen 2.939 N/A TRP 100.A N ILE 108.A O no hydrogen 3.185 N/A THR 102.A N ARG 106.A O no hydrogen 2.856 N/A THR 102.A OG1 ASP 104.A OD1 no hydrogen 2.664 N/A GLY 105.A N THR 102.A O no hydrogen 2.905 N/A ILE 108.A N TRP 100.A O no hydrogen 2.905 N/A GLN 110.A N TRP 97.A O no hydrogen 2.894 N/A GLN 110.A NE2 GLN 96.A O no hydrogen 2.775 N/A GLN 110.A NE2 SER 130.A O no hydrogen 2.751 N/A ILE 111.A N TRP 97.A O no hydrogen 3.222 N/A SER 112.A N ASP 109.A OD1 no hydrogen 3.077 N/A SER 112.A OG ASP 109.A OD2 no hydrogen 2.713 N/A GLY 113.A N ASP 109.A O no hydrogen 3.121 N/A ALA 114.A N GLN 110.A O no hydrogen 2.716 N/A LEU 115.A N ILE 111.A O no hydrogen 2.978 N/A GLU 116.A N SER 112.A O no hydrogen 2.721 N/A THR 117.A N GLY 113.A O no hydrogen 3.046 N/A THR 117.A OG1 ASN 121.A O no hydrogen 3.449 N/A THR 117.A OG1 ASN 127.A OD1 no hydrogen 3.470 N/A LEU 118.A N ALA 114.A O no hydrogen 2.807 N/A ARG 119.A N LEU 115.A O no hydrogen 2.929 N/A ARG 119.A NH2 GLN 190.A O no hydrogen 3.405 N/A ASN 120.A N GLU 116.A O no hydrogen 2.844 N/A ASN 121.A N THR 117.A O no hydrogen 2.662 N/A SER 124.A N ASN 121.A O no hydrogen 2.989 N/A ARG 126.A N SER 124.A OG no hydrogen 2.937 N/A ILE 128.A N ARG 126.A O no hydrogen 2.638 N/A VAL 129.A N PHE 149.A O no hydrogen 2.883 N/A SER 130.A N GLN 110.A OE1 no hydrogen 2.971 N/A ALA 131.A N LEU 147.A O no hydrogen 2.905 N/A TRP 132.A N SER 130.A OG no hydrogen 3.158 N/A ASN 133.A N ALA 131.A O no hydrogen 2.894 N/A SER 135.A OG GLU 136.A OE2 no hydrogen 3.529 N/A GLU 136.A N ASN 133.A O no hydrogen 2.778 N/A LEU 137.A N VAL 134.A O no hydrogen 3.233 N/A ASN 139.A N GLU 136.A O no hydrogen 3.044 N/A MET 140.A N LEU 137.A O no hydrogen 2.976 N/A ALA 141.A N LEU 89.A O no hydrogen 3.047 N/A CYS 145.A N TYR 93.A OH no hydrogen 2.739 N/A CYS 145.A SG SER 166.A O no hydrogen 3.079 N/A HIS 146.A ND1 TYR 180.A OH no hydrogen 2.632 N/A LEU 147.A N TYR 163.A O no hydrogen 3.188 N/A PHE 149.A N VAL 129.A O no hydrogen 2.890 N/A GLN 150.A N GLN 161.A O no hydrogen 2.851 N/A LEU 151.A N ASN 127.A O no hydrogen 3.072 N/A TYR 152.A N SER 159.A O no hydrogen 3.083 N/A ALA 154.A N LYS 157.A O no hydrogen 2.926 N/A LEU 158.A N GLU 194.A O no hydrogen 2.852 N/A SER 159.A N TYR 152.A O no hydrogen 2.660 N/A SER 159.A OG GLU 197.A O no hydrogen 3.349 N/A CYS 160.A N GLU 197.A O no hydrogen 2.963 N/A CYS 160.A SG GLN 150.A O no hydrogen 4.002 N/A GLN 161.A N GLN 150.A O no hydrogen 2.975 N/A LEU 162.A N ILE 199.A O no hydrogen 2.786 N/A TYR 163.A N LEU 148.A O no hydrogen 2.912 N/A GLN 164.A N THR 201.A O no hydrogen 2.914 N/A GLN 164.A NE2 SER 166.A O no hydrogen 2.956 N/A GLN 164.A NE2 ASN 176.A OD1 no hydrogen 3.167 N/A ARG 165.A N CYS 145.A O no hydrogen 3.085 N/A ARG 165.A NE PRO 144.A O no hydrogen 2.918 N/A ARG 165.A NH1 PRO 143.A O no hydrogen 3.365 N/A ALA 167.A N ASP 204.A O no hydrogen 2.893 N/A MET 169.A N HIS 206.A O no hydrogen 3.029 N/A LEU 171.A N ASP 168.A OD1 no hydrogen 3.144 N/A GLY 172.A N ASP 168.A O no hydrogen 2.993 N/A VAL 173.A N ASP 168.A O no hydrogen 2.968 N/A ASN 176.A N GLY 172.A O no hydrogen 3.017 N/A ILE 177.A N VAL 173.A O no hydrogen 2.984 N/A ALA 178.A N PRO 174.A O no hydrogen 3.184 N/A SER 179.A N PHE 175.A O no hydrogen 2.855 N/A TYR 180.A N ASN 176.A O no hydrogen 3.042 N/A TYR 180.A OH HIS 146.A ND1 no hydrogen 2.632 N/A ALA 181.A N ILE 177.A O no hydrogen 2.907 N/A LEU 182.A N ALA 178.A O no hydrogen 2.944 N/A LEU 183.A N SER 179.A O no hydrogen 2.848 N/A THR 184.A N TYR 180.A O no hydrogen 2.895 N/A HIS 185.A N ALA 181.A O no hydrogen 3.076 N/A MET 186.A N LEU 182.A O no hydrogen 3.076 N/A PHE 187.A N LEU 183.A O no hydrogen 3.097 N/A ALA 188.A N THR 184.A O no hydrogen 2.932 N/A GLN 189.A N HIS 185.A O no hydrogen 2.889 N/A GLN 189.A NE2 TYR 240.A OH no hydrogen 2.421 N/A GLN 190.A N MET 186.A O no hydrogen 3.209 N/A GLN 190.A NE2 ALA 234.A O no hydrogen 3.293 N/A GLN 190.A NE2 TYR 240.A OH no hydrogen 2.680 N/A ALA 191.A N PHE 187.A O no hydrogen 2.919 N/A GLY 192.A N GLN 189.A O no hydrogen 3.117 N/A LEU 193.A N ALA 188.A O no hydrogen 2.691 N/A GLU 194.A N GLY 156.A O no hydrogen 3.049 N/A GLY 196.A N LEU 158.A O no hydrogen 2.679 N/A GLU 197.A N SER 159.A OG no hydrogen 2.824 N/A PHE 198.A N PHE 35.A O no hydrogen 3.017 N/A ILE 199.A N CYS 160.A O no hydrogen 2.800 N/A TRP 200.A N ILE 33.A O no hydrogen 2.738 N/A TRP 200.A NE1 GLN 164.A OE1 no hydrogen 2.808 N/A THR 201.A N LEU 162.A O no hydrogen 2.876 N/A THR 201.A OG1 GLN 161.A OE1 no hydrogen 2.787 N/A GLY 202.A N GLN 31.A O no hydrogen 2.663 N/A GLY 203.A N GLN 164.A O no hydrogen 2.784 N/A ASP 204.A N ARG 165.A O no hydrogen 2.948 N/A CYS 205.A N LEU 28.A O no hydrogen 2.869 N/A CYS 205.A SG GLY 203.A O no hydrogen 3.200 N/A HIS 206.A N ALA 167.A O no hydrogen 3.067 N/A HIS 206.A ND1 ASP 204.A O no hydrogen 2.969 N/A HIS 206.A ND1 ASP 204.A OD2 no hydrogen 2.991 N/A ILE 207.A N THR 26.A O no hydrogen 2.841 N/A ASP 209.A N GLY 24.A O no hydrogen 2.946 N/A HIS 211.A N TYR 208.A O no hydrogen 3.267 N/A HIS 211.A NE2 LYS 259.A O no hydrogen 2.568 N/A LYS 212.A N ASP 209.A O no hydrogen 3.080 N/A LYS 212.A NZ GLU 213.A OE1 no hydrogen 2.929 N/A GLN 214.A NE2 ASN 210.A O no hydrogen 3.370 N/A VAL 215.A N HIS 211.A O no hydrogen 2.936 N/A ALA 216.A N LYS 212.A O no hydrogen 3.081 N/A GLU 217.A N GLU 213.A O no hydrogen 2.971 N/A GLN 218.A N GLN 214.A O no hydrogen 3.064 N/A GLN 218.A NE2 THR 46.A OG1 no hydrogen 3.130 N/A LEU 219.A N VAL 215.A O no hydrogen 2.805 N/A SER 220.A N ALA 216.A O no hydrogen 2.972 N/A SER 220.A N GLU 217.A O no hydrogen 3.154 N/A SER 220.A OG GLU 217.A O no hydrogen 3.000 N/A ARG 221.A N GLN 218.A O no hydrogen 3.118 N/A ARG 221.A NE GLU 217.A OE1 no hydrogen 2.952 N/A ARG 221.A NH1 THR 46.A O no hydrogen 3.313 N/A ARG 221.A NH1 PRO 254.A O no hydrogen 2.877 N/A ARG 221.A NH2 GLU 217.A OE1 no hydrogen 3.245 N/A ARG 224.A N THR 45.A OG1 no hydrogen 2.717 N/A ARG 224.A NH1 ASP 251.A O no hydrogen 2.785 N/A TYR 226.A OH PRO 4.A O no hydrogen 2.751 N/A THR 228.A N SER 248.A O no hydrogen 3.000 N/A GLU 230.A N THR 246.A O no hydrogen 3.023 N/A ASN 232.A N ASP 244.A O no hydrogen 2.981 N/A LYS 233.A NZ GLN 189.A O no hydrogen 3.426 N/A PHE 238.A N SER 236.A OG no hydrogen 3.095 N/A GLU 239.A N SER 236.A O no hydrogen 3.398 N/A SER 241.A N ASP 244.A OD2 no hydrogen 2.934 N/A SER 241.A OG ASP 244.A OD2 no hydrogen 3.104 N/A ASP 244.A N SER 241.A O no hydrogen 2.797 N/A ILE 245.A N PHE 242.A O no hydrogen 3.080 N/A THR 246.A N GLU 230.A O no hydrogen 3.256 N/A SER 248.A N THR 228.A O no hydrogen 2.984 N/A SER 248.A OG GLU 230.A OE1 no hydrogen 2.975 N/A SER 248.A OG GLU 230.A OE2 no hydrogen 3.202 N/A TYR 250.A OH LEU 44.A O no hydrogen 2.459 N/A HIS 253.A N THR 45.A O no hydrogen 3.083 N/A HIS 253.A NE2 GLU 222.A O no hydrogen 2.698 N/A