Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4h1x_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 3.A N THR 248.A O no hydrogen 2.792 N/A GLU 4.A N ASN 58.A O no hydrogen 2.933 N/A ILE 6.A N ILE 60.A O no hydrogen 2.756 N/A SER 7.A N VAL 41.A O no hydrogen 2.805 N/A SER 7.A OG ARG 8.A O no hydrogen 2.802 N/A ARG 8.A N TYR 62.A OH no hydrogen 3.032 N/A ARG 8.A NE GLU 9.A OE1 no hydrogen 2.831 N/A ARG 8.A NH2 GLU 9.A OE1 no hydrogen 3.240 N/A ARG 8.A NH2 GLU 9.A OE2 no hydrogen 3.200 N/A GLU 9.A N GLU 9.A OE1 no hydrogen 2.674 N/A SER 12.A N GLU 9.A O no hydrogen 3.099 N/A ARG 15.A N SER 12.A OG no hydrogen 3.109 N/A ARG 15.A NE ASP 34.A OD2 no hydrogen 3.009 N/A ARG 15.A NH1 ARG 8.A O no hydrogen 2.932 N/A ARG 15.A NH2 ASP 34.A OD2 no hydrogen 3.006 N/A GLY 16.A N SER 12.A O no hydrogen 3.009 N/A ALA 17.A N GLY 13.A O no hydrogen 2.964 N/A PHE 18.A N THR 14.A O no hydrogen 2.884 N/A THR 19.A N ARG 15.A O no hydrogen 2.924 N/A THR 19.A OG1 ARG 15.A O no hydrogen 2.891 N/A THR 19.A OG1 GLY 16.A O no hydrogen 3.248 N/A GLU 20.A N GLY 16.A O no hydrogen 3.032 N/A ILE 21.A N ALA 17.A O no hydrogen 2.854 N/A THR 22.A N PHE 18.A O no hydrogen 3.030 N/A THR 22.A OG1 PHE 18.A O no hydrogen 2.799 N/A THR 22.A OG1 THR 19.A O no hydrogen 3.420 N/A GLY 23.A N GLU 20.A O no hydrogen 3.173 N/A LEU 25.A N THR 19.A O no hydrogen 2.984 N/A LYS 26.A N ILE 33.A O no hydrogen 3.003 N/A LYS 26.A NZ GLY 23.A O no hydrogen 2.813 N/A ASP 28.A N LYS 31.A O no hydrogen 3.184 N/A LYS 32.A NZ GLU 20.A OE1 no hydrogen 3.400 N/A ILE 33.A N LYS 26.A O no hydrogen 2.744 N/A ASN 35.A N ILE 24.A O no hydrogen 2.890 N/A THR 36.A N ASP 34.A OD1 no hydrogen 2.995 N/A THR 36.A OG1 ASP 34.A OD1 no hydrogen 2.596 N/A ALA 37.A N PHE 243.A O no hydrogen 2.743 N/A ALA 40.A N ALA 37.A O no hydrogen 3.150 N/A VAL 41.A N VAL 5.A O no hydrogen 3.042 N/A GLN 43.A N SER 7.A O no hydrogen 2.933 N/A GLY 48.A N SER 45.A OG no hydrogen 3.092 N/A VAL 49.A N SER 45.A O no hydrogen 2.955 N/A LEU 50.A N THR 46.A O no hydrogen 2.976 N/A SER 51.A N GLU 47.A O no hydrogen 2.933 N/A ALA 52.A N GLY 48.A O no hydrogen 2.971 N/A VAL 53.A N VAL 49.A O no hydrogen 2.885 N/A GLN 54.A N LEU 50.A O no hydrogen 2.887 N/A GLY 55.A N SER 51.A O no hydrogen 2.857 N/A ASN 56.A N VAL 53.A O no hydrogen 3.379 N/A ASN 56.A ND2 ALA 52.A O no hydrogen 2.803 N/A ALA 59.A N ASN 56.A O no hydrogen 3.134 N/A ILE 60.A N GLU 4.A O no hydrogen 2.969 N/A GLY 61.A N VAL 225.A O no hydrogen 2.979 N/A ILE 63.A N ALA 223.A O no hydrogen 2.945 N/A SER 64.A OG.B ASP 220.A OD1 no hydrogen 3.139 N/A LEU 65.A N GLY 221.A O no hydrogen 2.770 N/A SER 67.A N SER 64.A O no hydrogen 3.005 N/A LEU 68.A N LEU 65.A O no hydrogen 3.129 N/A SER 71.A N THR 69.A OG1 no hydrogen 3.244 N/A SER 71.A OG.B THR 69.A OG1 no hydrogen 2.747 N/A VAL 72.A N THR 69.A O no hydrogen 3.418 N/A LYS 73.A N VAL 226.A O no hydrogen 2.841 N/A LYS 73.A NZ ASN 230.A O no hydrogen 2.745 N/A LYS 73.A NZ ALA 232.A O no hydrogen 2.942 N/A LEU 75.A N VAL 224.A O no hydrogen 2.767 N/A GLU 76.A N SER 233.A O no hydrogen 2.810 N/A ILE 77.A N VAL 80.A O no hydrogen 3.012 N/A ASP 78.A N VAL 235.A O no hydrogen 3.046 N/A VAL 80.A N ILE 77.A O no hydrogen 3.037 N/A THR 86.A N SER 83.A OG no hydrogen 3.378 N/A THR 86.A OG1 LYS 81.A O no hydrogen 2.680 N/A THR 86.A OG1 SER 83.A O no hydrogen 3.300 N/A VAL 87.A N SER 83.A O no hydrogen 2.929 N/A LEU 88.A N ARG 84.A O no hydrogen 2.958 N/A ASP 89.A N ASP 85.A O no hydrogen 3.063 N/A GLY 90.A N VAL 87.A O no hydrogen 3.114 N/A GLU 91.A N ASP 89.A OD1 no hydrogen 3.012 N/A TYR 92.A N THR 86.A O no hydrogen 2.880 N/A TYR 92.A OH ILE 222.A O no hydrogen 2.551 N/A GLN 95.A N PRO 93.A O no hydrogen 3.024 N/A GLN 95.A NE2 VAL 87.A O no hydrogen 2.923 N/A GLN 95.A NE2 TYR 92.A O no hydrogen 2.783 N/A ARG 96.A N ASP 220.A O no hydrogen 2.999 N/A ARG 96.A NE ASP 220.A OD2 no hydrogen 3.014 N/A ARG 96.A NH1 SER 157.A OG no hydrogen 2.993 N/A ARG 96.A NH2 SER 157.A OG no hydrogen 3.175 N/A ARG 96.A NH2 ASP 220.A OD2 no hydrogen 3.258 N/A PHE 98.A N ALA 218.A O no hydrogen 2.824 N/A ASN 99.A N VAL 200.A O no hydrogen 2.793 N/A ASN 99.A ND2 ARG 202.A O no hydrogen 3.031 N/A ILE 100.A N ASP 215.A O no hydrogen 2.980 N/A VAL 101.A N GLY 199.A O no hydrogen 2.803 N/A TRP 102.A N THR 213.A O no hydrogen 3.041 N/A ASN 105.A N SER 103.A OG no hydrogen 3.011 N/A LEU 106.A N SER 103.A O no hydrogen 3.048 N/A GLY 110.A N SER 107.A OG no hydrogen 2.953 N/A GLN 111.A N SER 107.A O no hydrogen 2.883 N/A ASP 112.A N LYS 108.A O no hydrogen 2.886 N/A PHE 113.A N LEU 109.A O no hydrogen 2.911 N/A ILE 114.A N GLY 110.A O no hydrogen 2.960 N/A SER 115.A N GLN 111.A O no hydrogen 2.934 N/A SER 115.A OG.A GLN 111.A O no hydrogen 3.025 N/A PHE 116.A N ASP 112.A O no hydrogen 3.010 N/A ILE 117.A N PHE 113.A O no hydrogen 2.952 N/A HIS 118.A N ILE 114.A O no hydrogen 2.912 N/A HIS 118.A NE2 ASP 215.A OD2 no hydrogen 2.686 N/A SER 119.A N PHE 116.A O no hydrogen 3.100 N/A SER 119.A OG PHE 116.A O no hydrogen 2.602 N/A LYS 120.A N THR 139.A O no hydrogen 2.920 N/A GLN 121.A NE2 GLU 171.A OE2.A no hydrogen 3.525 N/A GLN 121.A NE2 GLU 171.A OE2.B no hydrogen 2.737 N/A GLY 122.A N SER 119.A OG no hydrogen 3.035 N/A GLN 123.A N SER 119.A O no hydrogen 2.872 N/A GLN 123.A NE2 HIS 118.A O no hydrogen 3.616 N/A GLN 123.A NE2 GLU 137.A O no hydrogen 3.195 N/A GLN 124.A N LYS 120.A O no hydrogen 2.967 N/A GLN 124.A NE2 ASP 128.A OD1 no hydrogen 2.839 N/A VAL 125.A N GLN 121.A O no hydrogen 3.173 N/A VAL 126.A N GLY 122.A O no hydrogen 3.280 N/A THR 127.A N GLN 123.A O no hydrogen 3.068 N/A THR 127.A OG1.A GLN 123.A O no hydrogen 3.422 N/A THR 127.A OG1.A GLN 124.A O no hydrogen 3.372 N/A THR 127.A OG1.B GLN 123.A O no hydrogen 3.148 N/A ASP 128.A N GLN 124.A O no hydrogen 2.850 N/A ASN 129.A N VAL 125.A O no hydrogen 3.060 N/A ASN 129.A N VAL 126.A O no hydrogen 3.256 N/A ASN 129.A ND2 VAL 125.A O no hydrogen 2.861 N/A LYS 130.A N THR 127.A O no hydrogen 3.016 N/A PHE 131.A N VAL 126.A O no hydrogen 3.206 N/A ILE 132.A N LEU 219.A O no hydrogen 3.099 N/A LYS 135.A N GLU 133.A OE2 no hydrogen 3.054 N/A TYR 141.A OH ASP 112.A OD2 no hydrogen 2.684 N/A SER 143.A OG GLU 171.A O no hydrogen 2.604 N/A SER 143.A OG ASN 172.A OD1 no hydrogen 2.901 N/A HIS 145.A N SER 143.A OG no hydrogen 3.007 N/A LEU 146.A N ASN 172.A OD1 no hydrogen 3.233 N/A SER 147.A OG GLU 174.A O no hydrogen 3.232 N/A GLY 148.A N GLU 174.A O no hydrogen 3.413 N/A LEU 150.A N THR 176.A O no hydrogen 2.887 N/A SER 151.A N ASP 197.A OD2 no hydrogen 2.741 N/A VAL 152.A N ASP 178.A O no hydrogen 2.839 N/A VAL 153.A N ILE 198.A O no hydrogen 2.944 N/A GLY 154.A N THR 180.A O no hydrogen 2.860 N/A SER 155.A OG SER 201.A OG no hydrogen 2.681 N/A SER 157.A N SER 155.A OG no hydrogen 3.188 N/A VAL 158.A N SER 155.A O no hydrogen 3.223 N/A SER 159.A N THR 156.A O no hydrogen 3.263 N/A SER 159.A OG.A SER 155.A O no hydrogen 3.187 N/A SER 159.A OG.A THR 156.A O no hydrogen 3.474 N/A SER 159.A OG.A SER 181.A OG no hydrogen 2.476 N/A SER 159.A OG.B THR 156.A O no hydrogen 2.665 N/A LYS 163.A N SER 160.A O no hydrogen 3.166 N/A LEU 164.A N LEU 161.A O no hydrogen 3.014 N/A GLU 166.A N GLU 162.A O no hydrogen 2.886 N/A ALA 167.A N LYS 163.A O no hydrogen 3.102 N/A TYR 168.A N LEU 164.A O no hydrogen 2.951 N/A TYR 168.A OH ASP 112.A OD2 no hydrogen 2.539 N/A LYS 169.A N ALA 165.A O no hydrogen 2.873 N/A LYS 170.A N GLU 166.A O no hydrogen 3.124 N/A GLU 171.A N TYR 168.A O no hydrogen 3.043 N/A ASN 172.A N TYR 168.A O no hydrogen 2.843 N/A ASN 172.A ND2 TYR 141.A OH no hydrogen 2.931 N/A ASN 172.A ND2 TYR 168.A O no hydrogen 3.210 N/A VAL 175.A N ASN 172.A O no hydrogen 3.135 N/A THR 176.A N GLY 148.A O no hydrogen 2.933 N/A ASP 178.A N LEU 150.A O no hydrogen 2.896 N/A THR 180.A N VAL 152.A O no hydrogen 2.747 N/A SER 181.A OG SER 159.A OG.A no hydrogen 2.476 N/A ASN 182.A N GLY 154.A O no hydrogen 2.857 N/A GLY 183.A N ASN 182.A OD1 no hydrogen 2.840 N/A GLY 187.A N GLY 183.A O no hydrogen 3.048 N/A ILE 188.A N SER 184.A O no hydrogen 2.996 N/A THR 189.A N SER 185.A O no hydrogen 3.050 N/A THR 189.A OG1 SER 185.A O no hydrogen 3.169 N/A ALA 190.A N ALA 186.A O no hydrogen 2.940 N/A VAL 191.A N GLY 187.A O no hydrogen 3.069 N/A LYS 192.A N ILE 188.A O no hydrogen 3.070 N/A LYS 192.A NZ GLU 207.A O no hydrogen 3.207 N/A LYS 192.A NZ GLU 208.A O no hydrogen 2.993 N/A LYS 192.A NZ LYS 210.A O no hydrogen 3.292 N/A GLU 193.A N THR 189.A O no hydrogen 2.809 N/A LYS 194.A N VAL 191.A O no hydrogen 3.129 N/A THR 195.A N ALA 190.A O no hydrogen 2.883 N/A THR 195.A OG1 ALA 190.A O no hydrogen 3.416 N/A ALA 196.A N ALA 190.A O no hydrogen 3.217 N/A ASP 197.A N SER 151.A O no hydrogen 2.844 N/A ILE 198.A N SER 151.A O no hydrogen 3.239 N/A GLY 199.A N VAL 101.A O no hydrogen 2.849 N/A SER 201.A N SER 184.A OG no hydrogen 3.112 N/A SER 201.A OG SER 155.A OG no hydrogen 2.681 N/A ARG 202.A NH1 GLU 203.A O no hydrogen 3.156 N/A ARG 202.A NH1 GLU 208.A OE1 no hydrogen 2.724 N/A ARG 202.A NH1 GLU 208.A OE2 no hydrogen 3.399 N/A ARG 202.A NH2 GLU 208.A OE2 no hydrogen 2.858 N/A THR 205.A N GLU 208.A OE1 no hydrogen 2.912 N/A GLU 208.A N THR 205.A OG1 no hydrogen 3.047 N/A GLY 209.A N THR 205.A O no hydrogen 2.932 N/A LYS 210.A N GLU 207.A O no hydrogen 3.375 N/A SER 211.A OG LYS 210.A O no hydrogen 2.471 N/A LEU 212.A N GLY 209.A O no hydrogen 2.965 N/A THR 213.A N TRP 102.A O no hydrogen 2.933 N/A ASP 215.A N ILE 100.A O no hydrogen 2.921 N/A ILE 217.A N PHE 98.A O no hydrogen 2.881 N/A LEU 219.A N ILE 132.A O no hydrogen 2.803 N/A ASP 220.A N ARG 96.A O no hydrogen 2.873 N/A ILE 222.A N LEU 94.A O no hydrogen 2.903 N/A ALA 223.A N ILE 63.A O no hydrogen 2.796 N/A VAL 225.A N GLY 61.A O no hydrogen 2.843 N/A VAL 226.A N LYS 73.A O no hydrogen 2.870 N/A ASN 227.A ND2 VAL 53.A O no hydrogen 2.869 N/A ASN 227.A ND2 GLN 54.A O no hydrogen 2.902 N/A ASN 228.A ND2 LYS 70.A O no hydrogen 2.889 N/A ASP 229.A N ASN 227.A OD1 no hydrogen 2.937 N/A ASN 230.A N ASN 227.A O no hydrogen 3.015 N/A ALA 232.A N ASN 230.A OD1 no hydrogen 2.950 N/A VAL 235.A N GLU 76.A O no hydrogen 2.955 N/A SER 236.A N GLU 238.A OE1 no hydrogen 3.163 N/A GLU 238.A N SER 236.A OG no hydrogen 3.050 N/A LEU 239.A N SER 236.A O no hydrogen 2.869 N/A ASP 241.A N ALA 237.A O no hydrogen 2.940 N/A VAL 242.A N GLU 238.A O no hydrogen 2.794 N/A PHE 243.A N LEU 239.A O no hydrogen 3.057 N/A SER 244.A N ALA 240.A O no hydrogen 2.892 N/A SER 244.A OG ALA 240.A O no hydrogen 2.789 N/A SER 244.A OG ASP 241.A O no hydrogen 3.308 N/A GLY 245.A N VAL 242.A O no hydrogen 3.096 N/A LYS 246.A N ASP 241.A O no hydrogen 2.722 N/A LEU 247.A N ASP 241.A O no hydrogen 3.183 N/A THR 249.A OG1 ASP 251.A OD1 no hydrogen 2.865 N/A TRP 250.A N GLY 1.A O no hydrogen 2.956 N/A TRP 250.A NE1 ASN 58.A O no hydrogen 2.992 N/A LYS 252.A N THR 249.A O no hydrogen 3.320 N/A ILE 253.A N TRP 250.A O no hydrogen 2.904 N/A